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 Tissue Engineering
"Tissue Engineering" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity. Generating tissue in vitro for clinical applications, such as replacing wounded tissues or impaired organs. The use of TISSUE SCAFFOLDING enables the generation of complex multi-layered tissues and tissue structures.
| Descriptor ID | D023822 |
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| MeSH Number(s) | E05.200.249.750
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| Concepts/Terms | Tissue Engineering
- • Tissue Engineering
- • Engineering, Tissue
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Below are MeSH descriptors whose meaning is more general than "Tissue Engineering". • Analytical, Diagnostic and Therapeutic Techniques and Equipment [E] Below are MeSH descriptors whose meaning is related to "Tissue Engineering". • Culture TechniquesBelow are MeSH descriptors whose meaning is more specific than "Tissue Engineering". • Tissue Engineering This graph shows the total number of publications written about "Tissue Engineering" by people in Harvard Catalyst Profiles by year, and whether "Tissue Engineering" was a major or minor topic of these publication. In all years combined, a total of 721 publications were written by people in Profiles. Below are the publications written about "Tissue Engineering" that have been cited the most by articles in Pubmed Central. - Langer R, Tirrell DA. Designing materials for biology and medicine. Nature. 2004 Apr 1; 428(6982):487-92.
Cited: 27 times - Li WJ, Laurencin CT, Caterson EJ, Tuan RS, Ko FK. Electrospun nanofibrous structure: a novel scaffold for tissue engineering. J Biomed Mater Res. 2002 Jun 15; 60(4):613-21.
Cited: 17 times - Khademhosseini A, Langer R, Borenstein J, Vacanti JP. Microscale technologies for tissue engineering and biology. Proc Natl Acad Sci U S A. 2006 Feb 21; 103(8):2480-7.
Cited: 16 times - Levenberg S, Rouwkema J, Macdonald M, Garfein ES, Kohane DS, Darland DC, Marini R, van Blitterswijk CA, Mulligan RC, D'Amore PA, Langer R. Engineering vascularized skeletal muscle tissue. Nat Biotechnol. 2005 Jul; 23(7):879-84.
Cited: 13 times - Koike N, Fukumura D, Gralla O, Au P, Schechner JS, Jain RK. Tissue engineering: creation of long-lasting blood vessels. Nature. 2004 Mar 11; 428(6979):138-9.
Cited: 13 times - Zimmermann WH, Melnychenko I, Wasmeier G, Didié M, Naito H, Nixdorff U, Hess A, Budinsky L, Brune K, Michaelis B, Dhein S, Schwoerer A, Ehmke H, Eschenhagen T. Engineered heart tissue grafts improve systolic and diastolic function in infarcted rat hearts. Nat Med. 2006 Apr; 12(4):452-8.
Cited: 11 times - Davis ME, Hsieh PC, Takahashi T, Song Q, Zhang S, Kamm RD, Grodzinsky AJ, Anversa P, Lee RT. Local myocardial insulin-like growth factor 1 (IGF-1) delivery with biotinylated peptide nanofibers improves cell therapy for myocardial infarction. Proc Natl Acad Sci U S A. 2006 May 23; 103(21):8155-60.
Cited: 10 times - Rabkin-Aikawa E, Farber M, Aikawa M, Schoen FJ. Dynamic and reversible changes of interstitial cell phenotype during remodeling of cardiac valves. J Heart Valve Dis. 2004 Sep; 13(5):841-7.
Cited: 10 times - Yoshimoto H, Shin YM, Terai H, Vacanti JP. A biodegradable nanofiber scaffold by electrospinning and its potential for bone tissue engineering. Biomaterials. 2003 May; 24(12):2077-82.
Cited: 10 times - Aikawa E, Whittaker P, Farber M, Mendelson K, Padera RF, Aikawa M, Schoen FJ. Human semilunar cardiac valve remodeling by activated cells from fetus to adult: implications for postnatal adaptation, pathology, and tissue engineering. Circulation. 2006 Mar 14; 113(10):1344-52.
Cited: 9 times
Below are the most recent publications written about "Tissue Engineering" by people in Profiles - Miller RE, Kopesky PW, Grodzinsky AJ. Growth factor delivery through self-assembling peptide scaffolds. Clin Orthop Relat Res. 2011 Oct; 469(10):2716-24.
- Toh WS, Lee EH, Cao T. Potential of human embryonic stem cells in cartilage tissue engineering and regenerative medicine. Stem Cell Rev. 2011 Sep; 7(3):544-59.
- Chen AA, Thomas DK, Ong LL, Schwartz RE, Golub TR, Bhatia SN. Humanized mice with ectopic artificial liver tissues. Proc Natl Acad Sci U S A. 2011 Jul 19; 108(29):11842-7.
- Nguyen LH, Kudva AK, Saxena NS, Roy K. Engineering articular cartilage with spatially-varying matrix composition and mechanical properties from a single stem cell population using a multi-layered hydrogel. Biomaterials. 2011 Oct; 32(29):6946-52.
- Burns-Hernandez LU, Greenberg JE. Harvard-MIT Division of Health Sciences and Technology. IEEE Pulse. 2011 Jul-Aug; 2(4):68-9.
- Duailibi MT, Duailibi SE, Duailibi Neto EF, Negreiros RM, Jorge WA, Ferreira LM, Vacanti JP, Yelick PC. Tooth tissue engineering: optimal dental stem cell harvest based on tooth development. Artif Organs. 2011 Jul; 35(7):E129-35.
- Ivkovic A, Marijanovic I, Hudetz D, Porter RM, Pecina M, Evans CH. Regenerative medicine and tissue engineering in orthopaedic surgery. Front Biosci (Elite Ed). 2011; 3:923-44.
- Gauvin R, Khademhosseini A. Microscale technologies and modular approaches for tissue engineering: moving toward the fabrication of complex functional structures. ACS Nano. 2011 Jun 28; 5(6):4258-64.
- Kang Y, Kim S, Khademhosseini A, Yang Y. Creation of bony microenvironment with CaP and cell-derived ECM to enhance human bone-marrow MSC behavior and delivery of BMP-2. Biomaterials. 2011 Sep; 32(26):6119-30.
- Sharma NS, Nagrath D, Yarmush ML. Metabolic profiling based quantitative evaluation of hepatocellular metabolism in presence of adipocyte derived extracellular matrix. PLoS One. 2011; 6(5):e20137.
Below are the earliest publications written about "Tissue Engineering" by people in Profiles - Hadlock TA, Vacanti JP, Cheney ML. Tissue engineering in facial plastic and reconstructive surgery. Facial Plast Surg. 1998; 14(3):197-203.
- Vacanti JP. Clinical implications of tissue engineering. Harv Dent Bull. 1998; 7(2):20-2.
- Chaikof EL. Engineering and material considerations in islet cell transplantation. Annu Rev Biomed Eng. 1999; 1:103-27.
- Saxena AK, Willital GH, Vacanti JP. Vascularized three-dimensional skeletal muscle tissue-engineering. Biomed Mater Eng. 2001; 11(4):275-81.
- Stock UA, Mayer JE. Tissue engineering of cardiac valves on the basis of PGA/PLA Co-polymers. J Long Term Eff Med Implants. 2001; 11(3-4):249-60.
- Hasirci V, Berthiaume F, Bondre SP, Gresser JD, Trantolo DJ, Toner M, Wise DL. Expression of liver-specific functions by rat hepatocytes seeded in treated poly(lactic-co-glycolic) acid biodegradable foams. Tissue Eng. 2001 Aug; 7(4):385-94.
- Murray MM, Spector M. The migration of cells from the ruptured human anterior cruciate ligament into collagen-glycosaminoglycan regeneration templates in vitro. Biomaterials. 2001 Sep; 22(17):2393-402.
- De Filippo RE, Bauer SB. New surgical techniques in pediatric urology. Curr Opin Urol. 2001 Nov; 11(6):591-6.
- Kaviani A, Perry TE, Dzakovic A, Jennings RW, Ziegler MM, Fauza DO. The amniotic fluid as a source of cells for fetal tissue engineering. J Pediatr Surg. 2001 Nov; 36(11):1662-5.
- Nasseri BA, Ogawa K, Vacanti JP. Tissue engineering: an evolving 21st-century science to provide biologic replacement for reconstruction and transplantation. Surgery. 2001 Nov; 130(5):781-4.
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People  People who have written about this concept. - Vacanti, Joseph
- Khademhosseini, Ali
- Langer, Robert
- Spector, Myron
- Fauza, Dario
- Yarmush, Martin
- Vacanti, Charles
- Mayer, John
- Grodzinsky, Alan
- Demirci, Utkan
Similar Concepts Other topics written about by people who have written about this concept. Top Journals Top journals in which articles about this concept have been published.
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