 Chondrocytes
"Chondrocytes" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity. Polymorphic cells that form cartilage.
| Descriptor ID | D019902 |
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| MeSH Number(s) | A11.329.171
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| Concepts/Terms | Chondrocytes
- • Chondrocytes
- • Chondrocyte
Chondroblasts
- • Chondroblasts
- • Chondroblast
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Below are MeSH descriptors whose meaning is more general than "Chondrocytes". • Anatomy [A] Below are MeSH descriptors whose meaning is more specific than "Chondrocytes". • Chondrocytes This graph shows the total number of publications written about "Chondrocytes" by people in Harvard Catalyst Profiles by year, and whether "Chondrocytes" was a major or minor topic of these publication. In all years combined, a total of 448 publications were written by people in Profiles. Below are the publications written about "Chondrocytes" that have been cited the most by articles in Pubmed Central. - Olsen BR, Reginato AM, Wang W. Bone development. Annu Rev Cell Dev Biol. 2000; 16:191-220.
Cited: 36 times - Schipani E, Ryan HE, Didrickson S, Kobayashi T, Knight M, Johnson RS. Hypoxia in cartilage: HIF-1alpha is essential for chondrocyte growth arrest and survival. Genes Dev. 2001 Nov 1; 15(21):2865-76.
Cited: 34 times - Satokata I, Ma L, Ohshima H, Bei M, Woo I, Nishizawa K, Maeda T, Takano Y, Uchiyama M, Heaney S, Peters H, Tang Z, Maxson R, Maas R. Msx2 deficiency in mice causes pleiotropic defects in bone growth and ectodermal organ formation. Nat Genet. 2000 Apr; 24(4):391-5.
Cited: 33 times - Hartmann C, Tabin CJ. Wnt-14 plays a pivotal role in inducing synovial joint formation in the developing appendicular skeleton. Cell. 2001 Feb 9; 104(3):341-51.
Cited: 26 times - Long F, Zhang XM, Karp S, Yang Y, McMahon AP. Genetic manipulation of hedgehog signaling in the endochondral skeleton reveals a direct role in the regulation of chondrocyte proliferation. Development. 2001 Dec; 128(24):5099-108.
Cited: 24 times - Chung UI, Schipani E, McMahon AP, Kronenberg HM. Indian hedgehog couples chondrogenesis to osteogenesis in endochondral bone development. J Clin Invest. 2001 Feb; 107(3):295-304.
Cited: 22 times - Kisiday J, Jin M, Kurz B, Hung H, Semino C, Zhang S, Grodzinsky AJ. Self-assembling peptide hydrogel fosters chondrocyte extracellular matrix production and cell division: implications for cartilage tissue repair. Proc Natl Acad Sci U S A. 2002 Jul 23; 99(15):9996-10001.
Cited: 18 times - Hartmann C, Tabin CJ. Dual roles of Wnt signaling during chondrogenesis in the chicken limb. Development. 2000 Jul; 127(14):3141-59.
Cited: 17 times - Minina E, Wenzel HM, Kreschel C, Karp S, Gaffield W, McMahon AP, Vortkamp A. BMP and Ihh/PTHrP signaling interact to coordinate chondrocyte proliferation and differentiation. Development. 2001 Nov; 128(22):4523-34.
Cited: 15 times - Zelzer E, Glotzer DJ, Hartmann C, Thomas D, Fukai N, Soker S, Olsen BR. Tissue specific regulation of VEGF expression during bone development requires Cbfa1/Runx2. Mech Dev. 2001 Aug; 106(1-2):97-106.
Cited: 15 times
Below are the most recent publications written about "Chondrocytes" by people in Profiles - von Keudell A, Gomoll AH, Bryant T, Minas T. Spontaneous osteonecrosis of the knee treated with autologous chondrocyte implantation, autologous bone-grafting, and osteotomy: a report of two cases with follow-up of seven and nine years. J Bone Joint Surg Am. 2011 Dec 21; 93(24):e149.
- Miller RE, Kopesky PW, Grodzinsky AJ. Growth factor delivery through self-assembling peptide scaffolds. Clin Orthop Relat Res. 2011 Oct; 469(10):2716-24.
- Yoo JJ, Bichara DA, Zhao X, Randolph MA, Gill TJ. Implant-assisted meniscal repair in vivo using a chondrocyte-seeded flexible PLGA scaffold. J Biomed Mater Res A. 2011 Oct; 99(1):102-8.
- Kishi S, Abe H, Akiyama H, Tominaga T, Murakami T, Mima A, Nagai K, Kishi F, Matsuura M, Matsubara T, Iehara N, Ueda O, Fukushima N, Jishage K, Doi T. SOX9 protein induces a chondrogenic phenotype of mesangial cells and contributes to advanced diabetic nephropathy. J Biol Chem. 2011 Sep 16; 286(37):32162-9.
- Idelevich A, Rais Y, Monsonego-Ornan E. Bone Gla protein increases HIF-1alpha-dependent glucose metabolism and induces cartilage and vascular calcification. Arterioscler Thromb Vasc Biol. 2011 Sep; 31(9):e55-71.
- Idelevich A, Kerschnitzki M, Shahar R, Monsonego-Ornan E. 1,25(OH)2D3 alters growth plate maturation and bone architecture in young rats with normal renal function. PLoS One. 2011; 6(6):e20772.
- Seriwatanachai D, Densmore MJ, Sato T, Correa D, Neff L, Baron R, Lanske B. Deletion of Zfp521 rescues the growth plate phenotype in a mouse model of Jansen metaphyseal chondrodysplasia. FASEB J. 2011 Sep; 25(9):3057-67.
- Dougherty SS, Santangelo KS, Bertone AL. Evaluation of the ability of two transfection reagents to deliver small interfering RNA molecules to equine and guinea pig cartilage in vitro. Am J Vet Res. 2011 Jun; 72(6):813-9.
- Rolauffs B, Rothdiener M, Bahrs C, Badke A, Weise K, Kuettner KE, Kurz B, Aurich M, Grodzinsky AJ, Aicher WK. Onset of preclinical osteoarthritis: the angular spatial organization permits early diagnosis. Arthritis Rheum. 2011 Jun; 63(6):1637-47.
- Nakamura Y, Inloes JB, Katagiri T, Kobayashi T. Chondrocyte-specific microRNA-140 regulates endochondral bone development and targets Dnpep to modulate bone morphogenetic protein signaling. Mol Cell Biol. 2011 Jul; 31(14):3019-28.
Below are the earliest publications written about "Chondrocytes" by people in Profiles - Breinan HA, Minas T, Hsu HP, Nehrer S, Sledge CB, Spector M. Effect of cultured autologous chondrocytes on repair of chondral defects in a canine model. J Bone Joint Surg Am. 1997 Oct; 79(10):1439-51.
- Kokenyesi R, Silbert JE. Immortalized, cloned mouse chondrocytic cells (MC615) produce three different matrix proteoglycans with core-protein-specific chondroitin/dermatan sulphate structures. Biochem J. 1997 Nov 1; 327 ( Pt 3):831-9.
- Toma CD, Schaffer JL, Meazzini MC, Zurakowski D, Nah HD, Gerstenfeld LC. Developmental restriction of embryonic calvarial cell populations as characterized by their in vitro potential for chondrogenic differentiation. J Bone Miner Res. 1997 Dec; 12(12):2024-39.
- Cao Y, Rodriguez A, Vacanti M, Ibarra C, Arevalo C, Vacanti CA. Comparative study of the use of poly(glycolic acid), calcium alginate and pluronics in the engineering of autologous porcine cartilage. J Biomater Sci Polym Ed. 1998; 9(5):475-87.
- Buckwalter JA, Mankin HJ. Articular cartilage: tissue design and chondrocyte-matrix interactions. Instr Course Lect. 1998; 47:477-86.
- Peretti GM, Randolph MA, Caruso EM, Rossetti F, Zaleske DJ. Bonding of cartilage matrices with cultured chondrocytes: an experimental model. J Orthop Res. 1998 Jan; 16(1):89-95.
- Quinn TM, Grodzinsky AJ, Buschmann MD, Kim YJ, Hunziker EB. Mechanical compression alters proteoglycan deposition and matrix deformation around individual cells in cartilage explants. J Cell Sci. 1998 Mar; 111 ( Pt 5):573-83.
- Sims CD, Butler PE, Cao YL, Casanova R, Randolph MA, Black A, Vacanti CA, Yaremchuk MJ. Tissue engineered neocartilage using plasma derived polymer substrates and chondrocytes. Plast Reconstr Surg. 1998 May; 101(6):1580-5.
- Quinn TM, Grodzinsky AJ, Hunziker EB, Sandy JD. Effects of injurious compression on matrix turnover around individual cells in calf articular cartilage explants. J Orthop Res. 1998 Jul; 16(4):490-9.
- Hecht JT, Deere M, Putnam E, Cole W, Vertel B, Chen H, Lawler J. Characterization of cartilage oligomeric matrix protein (COMP) in human normal and pseudoachondroplasia musculoskeletal tissues. Matrix Biol. 1998 Aug; 17(4):269-78.
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People  People who have written about this concept. - Grodzinsky, Alan
- Spector, Myron
- Kronenberg, Henry
- Glowacki, Julie
- Vacanti, Charles
- Yaremchuk, Michael
- Demay, Marie
- Eavey, Roland
- Kobayashi, Tatsuya
- Randolph, Mark
Similar Concepts Other topics written about by people who have written about this concept. Top Journals Top journals in which articles about this concept have been published.
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