Ho J, Mahajan J, Taylor M, Byers A, Arauz P, Kwon YM
Metallosis in cemented titanium alloy total knee arthroplasty without apparent metal-on-metal articulation. Knee. 2018 Aug; 25(4):728-731.
Metallosis in cemented titanium alloy total knee arthroplasty without apparent metal-on-metal articulation.
In-vivo analysis of sliding distance and cross-shear in Bi-cruciate retaining total knee arthroplasty. J Biomech. 2018 08 22; 77:8-15.
In-vivo analysis of sliding distance and cross-shear in Bi-cruciate retaining total knee arthroplasty.
Manalo JPM, Castillo T, Hennessy D, Peng Y, Schurko B, Kwon YM
Preoperative opioid medication use negatively affect health related quality of life after total knee arthroplasty. Knee. 2018 Oct; 25(5):946-951.
Preoperative opioid medication use negatively affect health related quality of life after total knee arthroplasty.
Assistant Professor of Orthopedic Surgery
Professor of Orthopedic Surgery, Emeritus
Associate Professor of Orthopedic Surgery
Instructor in Orthopedic Surgery, Part-time
Alan Gerry Professor of Orthopedic Surgery, Emeritus
Edith M. Ashley Professor of Orthopedic Surgery, Emeritus
Klemt C, Simeone FJ, Melnic CM, Tirumala V, Xiong L, Kwon YM
MARS MRI assessment of fatty degeneration of the gluteal muscles in patients with THA: reliability and accuracy of commonly used classification systems. Skeletal Radiol. 2021 Apr; 50(4):665-672.
MARS MRI assessment of fatty degeneration of the gluteal muscles in patients with THA: reliability and accuracy of commonly used classification systems.
Klemt C, Limmahakhun S, Bounajem G, Melnic CM, Harvey MJ, Kwon YM
Archives of orthopaedic and trauma surgery
Outcome of revision surgery for adverse local tissue reactions in patients with recalled total hip arthroplasty. Arch Orthop Trauma Surg. 2022 Oct; 142(10):2577-2583.
Outcome of revision surgery for adverse local tissue reactions in patients with recalled total hip arthroplasty.
Klemt C, Uzosike AC, Harvey MJ, Laurencin S, Habibi Y, Kwon YM
Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA
Neural network models accurately predict discharge disposition after revision total knee arthroplasty? Knee Surg Sports Traumatol Arthrosc. 2022 Aug; 30(8):2591-2599.
Neural network models accurately predict discharge disposition after revision total knee arthroplasty?
Klemt C, Laurencin S, Uzosike AC, Burns JC, Costales TG, Yeo I, Habibi Y, Kwon YM
Machine learning models accurately predict recurrent infection following revision total knee arthroplasty for periprosthetic joint infection. Knee Surg Sports Traumatol Arthrosc. 2022 Aug; 30(8):2582-2590.
Machine learning models accurately predict recurrent infection following revision total knee arthroplasty for periprosthetic joint infection.
Klemt C, Harvey MJ, Robinson MG, Esposito JG, Yeo I, Kwon YM
Machine learning algorithms predict extended postoperative opioid use in primary total knee arthroplasty. Knee Surg Sports Traumatol Arthrosc. 2022 Aug; 30(8):2573-2581.
Machine learning algorithms predict extended postoperative opioid use in primary total knee arthroplasty.
Metal Articulations as a Source of Total Hip Arthroplasty Pain. J Arthroplasty. 2022 08; 37(8):1483-1487.
Metal Articulations as a Source of Total Hip Arthroplasty Pain.
Cohen-Levy WB, Klemt C, Tirumala V, Burns JC, Barghi A, Habibi Y, Kwon YM
Artificial neural networks for the prediction of transfusion rates in primary total hip arthroplasty. Arch Orthop Trauma Surg. 2023 Mar; 143(3):1643-1650.
Artificial neural networks for the prediction of transfusion rates in primary total hip arthroplasty.
In vivo Kinematics Analysis of total knee arthroplasty: Artificial Neural Network Approach 1/1/2022
Recent total knee arthroplasty (TKA) designs preserve or retain both the anterior and posterior cruciate ligaments (ACL and PCL) in order to enhance more physiological tibiofemoral kinematics and maintain proprioception. These implants include newly introduced non-modular femoral design of Bi-Cruciate Retaining (BCR) Total Knee Arthroplasty. Although preservation of the anterior and posterior cruciate ligament is thought to be necessary to achieve more normal kinematics, the effect of the ACL and PCL on knee joint kinematics after bicruciate-retaining knee arthroplasties may differ from that in the native knee as the articular surface in the tibiofemoral joint is altered following these knee arthroplasties. However, in vivo kinematics including six degrees of freedom (6DOF) and tibiofemoral articular contact motion of the knee in patients with ACL-PCL retaining knee arthroplasties has not been previously quantified. The research goal is quantification and comparison of 3 TKA designs (Cruciate Retaining (CR), Posterior Cruciate Substituting (PS) TKA, Bi-Cruciate Retaining (BCR) Total Knee Arthroplasty surgical system) in comparison with wellfunctioning contralateral knee in restoring normal in vivo knee kinematics during functional activity using validated Dual Fluoroscope Imaging System. In addition, machine learning (artificial neural network) will be utilized to assess the predictive values of in vivo kinematics. The responsibilities of the student at the Orthopaedic Bioengineering Lab, Massachusetts General Hospital will include quantitative investigation of the in vivo hip and knee biomechanics of patients with total joint replacements. Specifically, the research fellow will process CT and MRI images of patients to construct novel 3D anatomic models of the hip and knee and examine the optimal surgical implantation of joint replacements. This includes data gathering, analysis, and preparation of abstracts/manuscripts as well as presentation at national professional meeting. The student will work with a multidisciplinary team of engineers, surgeons in conducting human joint kinematics and kinetics evaluation using imaging and motion analysis techniques as machine learning (artificial neural network) will be utilized to assess the predictive values of in vivo kinematics. .
Klemt C, Cohen-Levy WB, Robinson MG, Burns JC, Alpaugh K, Yeo I, Kwon YM
Can machine learning models predict failure of revision total hip arthroplasty? Arch Orthop Trauma Surg. 2023 Jun; 143(6):2805-2812.
Can machine learning models predict failure of revision total hip arthroplasty?
Klemt C, Uzosike AC, Esposito JG, Harvey MJ, Yeo I, Subih M, Kwon YM
The utility of machine learning algorithms for the prediction of patient-reported outcome measures following primary hip and knee total joint arthroplasty. Arch Orthop Trauma Surg. 2023 Apr; 143(4):2235-2245.
The utility of machine learning algorithms for the prediction of patient-reported outcome measures following primary hip and knee total joint arthroplasty.
Yeo I, Klemt C, Melnic CM, Pattavina MH, De Oliveira BMC, Kwon YM
Predicting surgical operative time in primary total knee arthroplasty utilizing machine learning models. Arch Orthop Trauma Surg. 2023 Jun; 143(6):3299-3307.
Predicting surgical operative time in primary total knee arthroplasty utilizing machine learning models.
Klemt C, Tirumala V, Habibi Y, Buddhiraju A, Chen TL, Kwon YM
The utilization of artificial neural networks for the prediction of 90-day unplanned readmissions following total knee arthroplasty. Arch Orthop Trauma Surg. 2023 Jun; 143(6):3279-3289.
The utilization of artificial neural networks for the prediction of 90-day unplanned readmissions following total knee arthroplasty.
Chen TL, Buddhiraju A, Seo HH, Shimizu MR, Bacevich BM, Kwon YM
Can machine learning models predict prolonged length of hospital stay following primary total knee arthroplasty based on a national patient cohort data? Arch Orthop Trauma Surg. 2023 Dec; 143(12):7185-7193.
Can machine learning models predict prolonged length of hospital stay following primary total knee arthroplasty based on a national patient cohort data?
Buddhiraju A, Chen TL, Shimizu M, Seo HH, Esposito JG, Kwon YM
Do preoperative PROMIS scores independently predict 90-day readmission following primary total knee arthroplasty? Arch Orthop Trauma Surg. 2024 Feb; 144(2):861-867.
Do preoperative PROMIS scores independently predict 90-day readmission following primary total knee arthroplasty?
Chen TL, Shimizu MR, Buddhiraju A, Seo HH, Subih MA, Chen SF, Kwon YM
Medical & biological engineering & computing
Predicting 30-day unplanned hospital readmission after revision total knee arthroplasty: machine learning model analysis of a national patient cohort. Med Biol Eng Comput. 2024 Jul; 62(7):2073-2086.
Predicting 30-day unplanned hospital readmission after revision total knee arthroplasty: machine learning model analysis of a national patient cohort.
Buddhiraju A, Shimizu MR, Seo HH, Chen TL, RezazadehSaatlou M, Huang Z, Kwon YM
Generalizability of machine learning models predicting 30-day unplanned readmission after primary total knee arthroplasty using a nationally representative database. Med Biol Eng Comput. 2024 Aug; 62(8):2333-2341.
Generalizability of machine learning models predicting 30-day unplanned readmission after primary total knee arthroplasty using a nationally representative database.
Shimizu MR, Buddhiraju A, Kwon OJ, Chen TLW, Kerluku J, Kwon YM
Are social determinants of health associated with an increased length of hospitalization after revision total hip and knee arthroplasty? A comparison study of social deprivation indices. Arch Orthop Trauma Surg. 2024 Jul; 144(7):3045-3052.
Are social determinants of health associated with an increased length of hospitalization after revision total hip and knee arthroplasty? A comparison study of social deprivation indices.
Chen TL, RezazadehSaatlou M, Buddhiraju A, Seo HH, Shimizu MR, Kwon YM
Predicting extended hospital stay following revision total hip arthroplasty: a machine learning model analysis based on the ACS-NSQIP database. Arch Orthop Trauma Surg. 2024 Sep; 144(9):4411-4420.
Predicting extended hospital stay following revision total hip arthroplasty: a machine learning model analysis based on the ACS-NSQIP database.
Mittal A, Buddhiraju A, Abdullah Subih M, Lin-Wei Chen T, Shimizu M, Hojoon Seo H, Rezazadehsaatlou M, Xiao P, Kwon YM
International journal of medical informatics
Predicting prolonged length of stay following revision total knee arthroplasty: A national database analysis using machine learning models. Int J Med Inform. 2024 Dec; 192:105634.
Predicting prolonged length of stay following revision total knee arthroplasty: A national database analysis using machine learning models.
Buddhiraju A, Shimizu MR, Chen TL, Seo HH, Bacevich BM, Xiao P, Kwon YM
Comparing prediction accuracy for 30-day readmission following primary total knee arthroplasty: the ACS-NSQIP risk calculator versus a novel artificial neural network model. Knee Surg Relat Res. 2025 Jan 13; 37(1):3.
Comparing prediction accuracy for 30-day readmission following primary total knee arthroplasty: the ACS-NSQIP risk calculator versus a novel artificial neural network model.
Chen TL, Buddhiraju A, Bacevich BM, Seo HH, Shimizu MR, Kwon YM
Predicting 30-day reoperation following primary total knee arthroplasty: machine learning model outperforms the ACS risk calculator. Med Biol Eng Comput. 2025 Apr; 63(4):1131-1141.
Predicting 30-day reoperation following primary total knee arthroplasty: machine learning model outperforms the ACS risk calculator.
Salimy MS, Buddhiraju A, Chen TL, Mittal A, Xiao P, Kwon YM
Machine learning to predict periprosthetic joint infections following primary total hip arthroplasty using a national database. Arch Orthop Trauma Surg. 2025 Jan 17; 145(1):131.
Machine learning to predict periprosthetic joint infections following primary total hip arthroplasty using a national database.
Huang Z, Buddhiraju A, Chen TL, RezazadehSaatlou M, Chen SF, Bacevich BM, Xiao P, Kwon YM
Orthopaedics & traumatology, surgery & research : OTSR
Machine learning models based on a national-scale cohort accurately identify patients at high risk of deep vein thrombosis following primary total hip arthroplasty. Orthop Traumatol Surg Res. 2025 Jun; 111(4):104238.
Machine learning models based on a national-scale cohort accurately identify patients at high risk of deep vein thrombosis following primary total hip arthroplasty.
Knee motion symmetry was not restored in patients with unilateral bi-cruciate retaining total knee arthroplasty-in vivo three-dimensional kinematic analysis. Int Orthop. 2018 12; 42(12):2817-2823.
Knee motion symmetry was not restored in patients with unilateral bi-cruciate retaining total knee arthroplasty-in vivo three-dimensional kinematic analysis.
Klemt C, Tirumala V, Barghi A, Cohen-Levy WB, Robinson MG, Kwon YM
Artificial intelligence algorithms accurately predict prolonged length of stay following revision total knee arthroplasty. Knee Surg Sports Traumatol Arthrosc. 2022 Aug; 30(8):2556-2564.
Artificial intelligence algorithms accurately predict prolonged length of stay following revision total knee arthroplasty.
Klemt C, Chen W, Bounajem G, Tirumala V, Xiong L, Kwon YM
Outcome and risk factors of failures associated with revision total hip arthroplasty for recurrent dislocation. Arch Orthop Trauma Surg. 2022 Aug; 142(8):1801-1807.
Outcome and risk factors of failures associated with revision total hip arthroplasty for recurrent dislocation.
van den Kieboom J, Tirumala V, Xiong L, Klemt C, Kwon YM
Periprosthetic joint infection is the main reason for failure in patients following periprosthetic fracture treated with revision arthroplasty. Arch Orthop Trauma Surg. 2022 Dec; 142(12):3565-3574.
Periprosthetic joint infection is the main reason for failure in patients following periprosthetic fracture treated with revision arthroplasty.
Klemt C, Tirumala V, Smith EJ, Xiong L, Kwon YM
Complete blood platelet and lymphocyte ratios increase diagnostic accuracy of periprosthetic joint infection following total hip arthroplasty. Arch Orthop Trauma Surg. 2023 Mar; 143(3):1441-1449.
Complete blood platelet and lymphocyte ratios increase diagnostic accuracy of periprosthetic joint infection following total hip arthroplasty.
Three-dimensional in vivo difference between native acetabular version and acetabular component version influences iliopsoas impingement after total hip arthroplasty. Int Orthop. 2016 Sep; 40(9):1807-12.
Three-dimensional in vivo difference between native acetabular version and acetabular component version influences iliopsoas impingement after total hip arthroplasty.
Metal-on-metal total hip arthroplasty: risk factors for pseudotumours and clinical systematic evaluation. Int Orthop. 2017 05; 41(5):885-892.
Metal-on-metal total hip arthroplasty: risk factors for pseudotumours and clinical systematic evaluation.
In-vivo 3-Dimensional gait symmetry analysis in patients with bilateral total hip arthroplasty. J Biomech. 2018 08 22; 77:131-137.
In-vivo 3-Dimensional gait symmetry analysis in patients with bilateral total hip arthroplasty.
Tirumala V, Klemt C, van den Kieboom J, Xiong L, Kwon YM
Comparison of patient reported outcome measures after single versus two-stage revision for chronic infection of total hip arthroplasty: a retrospective propensity score matched cohort study. Arch Orthop Trauma Surg. 2021 Oct; 141(10):1789-1796.
Comparison of patient reported outcome measures after single versus two-stage revision for chronic infection of total hip arthroplasty: a retrospective propensity score matched cohort study.
Asymmetrical tibial polyethylene geometry-cruciate retaining total knee arthroplasty does not fully restore in-vivo articular contact kinematics during strenuous activities. Knee Surg Sports Traumatol Arthrosc. 2022 Feb; 30(2):652-660.
Asymmetrical tibial polyethylene geometry-cruciate retaining total knee arthroplasty does not fully restore in-vivo articular contact kinematics during strenuous activities.
Tsai TY, Li JS, Wang S, Scarborough D, Kwon YM
In-vivo 6 degrees-of-freedom kinematics of metal-on-polyethylene total hip arthroplasty during gait. J Biomech. 2014 May 07; 47(7):1572-6.
In-vivo 6 degrees-of-freedom kinematics of metal-on-polyethylene total hip arthroplasty during gait.
Does component alignment affect gait symmetry in unilateral total hip arthroplasty patients? Clin Biomech (Bristol). 2015 Oct; 30(8):802-7.
Does component alignment affect gait symmetry in unilateral total hip arthroplasty patients?
The effect of femoral neck osteotomy on femoral component position of a primary cementless total hip arthroplasty. Int Orthop. 2015 Dec; 39(12):2315-21.
The effect of femoral neck osteotomy on femoral component position of a primary cementless total hip arthroplasty.
Tsai TY, Dimitriou D, Hosseini A, Liow MHL, Torriani M, Li G, Kwon YM
Assessment of accuracy and precision of 3D reconstruction of unicompartmental knee arthroplasty in upright position using biplanar radiography. Med Eng Phys. 2016 07; 38(7):633-638.
Assessment of accuracy and precision of 3D reconstruction of unicompartmental knee arthroplasty in upright position using biplanar radiography.
Kwon YM, Khormaee S, Liow MH, Tsai TY, Freiberg AA, Rubash HE
The Journal of bone and joint surgery. American volume
Asymptomatic Pseudotumors in Patients with Taper Corrosion of a Dual-Taper Modular Femoral Stem: MARS-MRI and Metal Ion Study. J Bone Joint Surg Am. 2016 Oct 19; 98(20):1735-1740.
Asymptomatic Pseudotumors in Patients with Taper Corrosion of a Dual-Taper Modular Femoral Stem: MARS-MRI and Metal Ion Study.