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A Framework for Ethical Payment to Research Participants.
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Proceedings of the Association of American Physicians
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On Scarcity and the Value of Clinical Trials.
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Proceedings of the National Academy of Sciences of the United States of America
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Therapeutic innovation & regulatory science
Truth in Advertising: Disclosure of Participant Payment in Research Recruitment Materials. Ther Innov Regul Sci. 2018 05; 52(3):268-274.
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Rapamycin inhibits clonal expansion and adipogenic differentiation of 3T3-L1 cells.
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Analysis of CD4 and CD2 receptor function.
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The treatment of sickle cell anemia with induced hyponatremia. Blood Cells. 1982; 8(2):329-35.
The treatment of sickle cell anemia with induced hyponatremia.
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Identification of a physical interaction between calcineurin and nuclear factor of activated T cells (NFATp).
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Assessment of a shortened informed consent form for pediatric research: a pilot study. Pediatr Res. 2018 10; 84(4):516-519.
Assessment of a shortened informed consent form for pediatric research: a pilot study.
Balsari S, Fortenko A, Blaya JA, Gropper A, Jayaram M, Matthan R, Sahasranam R, Shankar M, Sarbadhikari SN, Bierer BE, Mandl KD, Mehendale S, Khanna T
Reimagining Health Data Exchange: An Application Programming Interface-Enabled Roadmap for India. J Med Internet Res. 2018 07 13; 20(7):e10725.
Reimagining Health Data Exchange: An Application Programming Interface-Enabled Roadmap for India.
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The role of functional cell surface antigens in T cell activation. Year Immunol. 1986; 2:39-59.
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Separable portions of the CD2 cytoplasmic domain involved in signaling and ligand avidity regulation. J Exp Med. 1993 Nov 01; 178(5):1831-6.
Separable portions of the CD2 cytoplasmic domain involved in signaling and ligand avidity regulation.
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Localization of the FK506-binding protein, FKBP 13, to the lumen of the endoplasmic reticulum. Biochem J. 1993 Sep 01; 294 ( Pt 2):511-5.
Localization of the FK506-binding protein, FKBP 13, to the lumen of the endoplasmic reticulum.
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Q-T prolongation and torsades de pointes ventricular tachycardia produced by the tetracyclic antidepressant agent maprotiline. Am J Cardiol. 1983 Mar 01; 51(5):904-6.
Q-T prolongation and torsades de pointes ventricular tachycardia produced by the tetracyclic antidepressant agent maprotiline.
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T-lymphocyte activation: the biology and function of CD2 and CD4. Immunol Rev. 1989 Oct; 111:267-94.
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Public Engagement, Notice-and-Comment Rulemaking, and the Common Rule. IRB. 2017 Jan-Feb; 39(1):17-9.
Public Engagement, Notice-and-Comment Rulemaking, and the Common Rule.
Bierer BE, Greenstein JL, Sleckman B, Ratnofsky S, Peterson A, Seed B, Burakoff SJ
Annals of the New York Academy of Sciences
Functional analysis of CD2, CD4, and CD8 in T-cell activation. Ann N Y Acad Sci. 1988; 532:199-206.
Functional analysis of CD2, CD4, and CD8 in T-cell activation.
Mentzer SJ, Remold-O'Donnell E, Crimmins MA, Bierer BE, Rosen FS, Burakoff SJ
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Bierer BE, Li R, Seltzer J, Sleeper LA, Frank E, Knirsch C, Aldinger CE, Levine RJ, Massaro J, Shah A, Barnes M, Snapinn S, Wittes J
Responsibilities of Data Monitoring Committees: Consensus Recommendations. Ther Innov Regul Sci. 2016 Sep; 50(5):648-659.
Responsibilities of Data Monitoring Committees: Consensus Recommendations.
Cell-mediated immunity. Immunol Ser. 1993; 58:187-212.
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Leveling the Joint Task Force Core Competencies for Clinical Research Professionals. Ther Innov Regul Sci. 2018 Oct 18; 2168479018799291.
Leveling the Joint Task Force Core Competencies for Clinical Research Professionals.
Fruman DA, Klee CB, Bierer BE, Burakoff SJ
Calcineurin phosphatase activity in T lymphocytes is inhibited by FK 506 and cyclosporin A. Proc Natl Acad Sci U S A. 1992 May 01; 89(9):3686-90.
Calcineurin phosphatase activity in T lymphocytes is inhibited by FK 506 and cyclosporin A.
Progress in clinical and biological research
Biology of cyclosporin A and FK506. Prog Clin Biol Res. 1994; 390:203-23.
Collins TL, Hahn WC, Bierer BE, Burakoff SJ
Current topics in microbiology and immunology
CD4, CD8 and CD2 in T cell adhesion and signaling. Curr Top Microbiol Immunol. 1993; 184:223-33.
CD4, CD8 and CD2 in T cell adhesion and signaling.
Fay JW, Wingard JR, Antin JH, Collins RH, Piñeiro LA, Blazar BR, Saral R, Bierer BE, Przepiorka D, Fitzsimmons WE, Maher RM, Weisdorf DJ
FK506 (Tacrolimus) monotherapy for prevention of graft-versus-host disease after histocompatible sibling allogenic bone marrow transplantation. Blood. 1996 Apr 15; 87(8):3514-9.
FK506 (Tacrolimus) monotherapy for prevention of graft-versus-host disease after histocompatible sibling allogenic bone marrow transplantation.
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Synergistic T cell activation via the physiological ligands for CD2 and the T cell receptor. J Exp Med. 1988 Sep 01; 168(3):1145-56.
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Identification and characterization of an immunophilin expressed during the clonal expansion phase of adipocyte differentiation.
Hutchcroft JE, Slavik JM, Lin H, Watanabe T, Bierer BE
Uncoupling activation-dependent HS1 phosphorylation from nuclear factor of activated T cells transcriptional activation in Jurkat T cells: differential signaling through CD3 and the costimulatory receptors CD2 and CD28. J Immunol. 1998 Nov 01; 161(9):4506-12.
Uncoupling activation-dependent HS1 phosphorylation from nuclear factor of activated T cells transcriptional activation in Jurkat T cells: differential signaling through CD3 and the costimulatory receptors CD2 and CD28.
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CD80 and CD86 are not equivalent in their ability to induce the tyrosine phosphorylation of CD28.
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CD59 costimulation of T cell activation. CD58 dependence and requirement for glycosylation. J Immunol. 1994 Sep 15; 153(6):2444-56.
CD59 costimulation of T cell activation. CD58 dependence and requirement for glycosylation.
Cross-linking CD28 leads to activation of 70-kDa S6 kinase. Eur J Immunol. 1994 Oct; 24(10):2364-8.
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T cell adhesion, avidity regulation and signaling: a molecular analysis of CD2.
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Inhibition of calcineurin phosphatase activity in adult bone marrow transplant patients treated with cyclosporine A. Blood. 1994 Dec 01; 84(11):3974-9.
Inhibition of calcineurin phosphatase activity in adult bone marrow transplant patients treated with cyclosporine A.
Wheeler C, Strawderman M, Ayash L, Churchill WH, Bierer BE, Elias A, Gilliland DG, Antman K, Guinan EC, Eder JP
Journal of clinical oncology : official journal of the American Society of Clinical Oncology
Prognostic factors for treatment outcome in autotransplantation of intermediate-grade and high-grade non-Hodgkin's lymphoma with cyclophosphamide, carmustine, and etoposide. J Clin Oncol. 1993 Jun; 11(6):1085-91.
Prognostic factors for treatment outcome in autotransplantation of intermediate-grade and high-grade non-Hodgkin's lymphoma with cyclophosphamide, carmustine, and etoposide.
Bierer BE, Strauss DH, White SA, Zarin DA
Universal Funder Responsibilities That Advance Social Value. Am J Bioeth. 2018 Nov; 18(11):30-32.
Universal Funder Responsibilities That Advance Social Value.
Hahn WC, Menzin E, Saito T, Germain RN, Bierer BE
The complete sequences of plasmids pFNeo and pMH-Neo: convenient expression vectors for high-level expression of eukaryotic genes in hematopoietic cell lines. Gene. 1993 May 30; 127(2):267-8.
The complete sequences of plasmids pFNeo and pMH-Neo: convenient expression vectors for high-level expression of eukaryotic genes in hematopoietic cell lines.
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Phorbol ester treatment inhibits phosphatidylinositol 3-kinase activation by, and association with, CD28, a T-lymphocyte surface receptor. Proc Natl Acad Sci U S A. 1995 Sep 12; 92(19):8808-12.
Phorbol ester treatment inhibits phosphatidylinositol 3-kinase activation by, and association with, CD28, a T-lymphocyte surface receptor.
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A role for calcineurin in degranulation of murine cytotoxic T lymphocytes. J Immunol. 1993 Apr 01; 150(7):2591-8.
A role for calcineurin in degranulation of murine cytotoxic T lymphocytes.
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Signal transduction pathways involved in T cell receptor-induced regulation of CD2 avidity for CD58.
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Characterization of HTLV-I in vivo infected T cell clones. IL-2-independent growth of nontransformed T cells. J Immunol. 1992 May 15; 148(10):3256-63.
Characterization of HTLV-I in vivo infected T cell clones. IL-2-independent growth of nontransformed T cells.
Krangel MS, Bierer BE, Devlin P, Clabby M, Strominger JL, McLean J, Brenner MB
T3 glycoprotein is functional although structurally distinct on human T-cell receptor gamma T lymphocytes. Proc Natl Acad Sci U S A. 1987 Jun; 84(11):3817-21.
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The Revised and Final Common Rule: An Unfinished Story. IRB. 2017 Nov-Dec; 39(6):6-10.
The Revised and Final Common Rule: An Unfinished Story.
Collins TL, Kassner PD, Bierer BE, Burakoff SJ
Adhesion receptors in lymphocyte activation. Curr Opin Immunol. 1994 Jun; 6(3):385-93.
Adhesion receptors in lymphocyte activation.
Vardeny O, Hernandez AF, Cohen LW, Franklin A, Baqai M, Palmer S, Bierer BE, Cobb N
Transitioning to the National Institutes of Health single institutional review board model: Piloting the use of the Streamlined, Multi-site, Accelerated Resources for Trials IRB Reliance. Clin Trials. 2019 06; 16(3):290-296.
Transitioning to the National Institutes of Health single institutional review board model: Piloting the use of the Streamlined, Multi-site, Accelerated Resources for Trials IRB Reliance.
Mongan Institute's Health Policy Center - MIHPC
Harvard T.H. Chan School of Public Health
Assistant Professor of Medicine, Part-time
Scientific Merit Predicates Ethical Review of Clinical Research. Ethics Hum Res. 2019 05; 41(3):29-32.
Scientific Merit Predicates Ethical Review of Clinical Research.
Parker B. Francis Distinguished Professor of Medicine
Social Media as an Ethical Tool for Retention in Clinical Trials. Am J Bioeth. 2019 06; 19(6):62-64.
Social Media as an Ethical Tool for Retention in Clinical Trials.
Credit data generators for data reuse. Nature. 2019 06; 570(7759):30-32.
Protecting Pregnant Women With Substance Use Disorders and Their Neonates Participating in Research. JAMA. 2019 Aug 20; 322(7):609-610.
Protecting Pregnant Women With Substance Use Disorders and Their Neonates Participating in Research.
Gelinas L, Crawford B, Kelman A, Bierer BE
Relocation of study participants for rare and ultra-rare disease trials: Ethics and operations. Contemp Clin Trials. 2019 09; 84:105812.
Relocation of study participants for rare and ultra-rare disease trials: Ethics and operations.
Aldinger CE, Ligibel J, Shin IH, Denninger JW, Bierer BE
Journal of clinical and translational science
Returning aggregate results of clinical trials: Empirical data of patient preferences. J Clin Transl Sci. 2018 Dec; 2(6):356-362.
Returning aggregate results of clinical trials: Empirical data of patient preferences.
Witte E, Winkler SJ, Myerson J, Kirby A, Biggers J, Do JM, Roth MT, Gateman AK, Cagliero E, Bierer BE
Development of a plain-language library of educational resources for research participants. J Clin Transl Sci. 2018 Feb; 2(1):27-30.
Development of a plain-language library of educational resources for research participants.
Cobb N, Witte E, Cervone M, Kirby A, MacFadden D, Nadler L, Bierer BE
The SMART IRB platform: A national resource for IRB review for multisite studies. J Clin Transl Sci. 2019 Aug; 3(4):129-139.
The SMART IRB platform: A national resource for IRB review for multisite studies.
The Journal of law, medicine & ethics : a journal of the American Society of Law, Medicine & Ethics
Research Subject Injury Compensation: The Ongoing Search for Fairness, Consistency and Clarity. J Law Med Ethics. 2019 12; 47(4):748-750.
Research Subject Injury Compensation: The Ongoing Search for Fairness, Consistency and Clarity.
Issues in the registration of database studies. J Clin Epidemiol. 2020 05; 121:29-31.
Issues in the registration of database studies.
Innovative statistical methodologies to subgroup analysis in clinical trials
Sonstein SA, Namenek Brouwer RJ, Gluck W, Robert Kolb H, Aldinger C, Bierer BE, Thomas Jones C
Leveling the Joint Task Force Core Competencies for Clinical Research Professionals. Ther Innov Regul Sci. 2020 01; 54(1):1-20.
Economic vulnerability and payment for research participation. Clin Trials. 2020 06; 17(3):264-272.
Economic vulnerability and payment for research participation.
Statham EE, White SA, Sonwane B, Bierer BE
Primed to comply: Individual participant data sharing statements on ClinicalTrials.gov. PLoS One. 2020; 15(2):e0226143.
Primed to comply: Individual participant data sharing statements on ClinicalTrials.gov.
Sim I, Stebbins M, Bierer BE, Butte AJ, Drazen J, Dzau V, Hernandez AF, Krumholz HM, Lo B, Munos B, Perakslis E, Rockhold F, Ross JS, Terry SF, Yamamoto KR, Zarin DA, Li R
Time for NIH to lead on data sharing. Science. 2020 03 20; 367(6484):1308-1309.
Peloquin D, DiMaio M, Bierer B, Barnes M
European journal of human genetics : EJHG
Disruptive and avoidable: GDPR challenges to secondary research uses of data. Eur J Hum Genet. 2020 06; 28(6):697-705.
Disruptive and avoidable: GDPR challenges to secondary research uses of data.
Innovation in biosafety oversight: The Harvard Catalyst Common Reciprocal IBC Reliance Authorization Agreement. J Clin Transl Sci. 2020 Apr; 4(2):90-95.
Innovation in biosafety oversight: The Harvard Catalyst Common Reciprocal IBC Reliance Authorization Agreement.
Holthaus K, Goldberg D, Connelly C, Corning B, Nascimento C, Witte E, Bierer BE
Facilitating collaborative animal research: The development and implementation of a Master Reciprocal Institutional Agreement for Animal Care and Use. J Clin Transl Sci. 2020 Apr; 4(2):96-101.
Facilitating collaborative animal research: The development and implementation of a Master Reciprocal Institutional Agreement for Animal Care and Use.
Committing to the Inclusion of Diverse Populations in Clinical Research. Ther Innov Regul Sci. 2020 07; 54(4):922-924.
Committing to the Inclusion of Diverse Populations in Clinical Research.
Ogburn EL, Bierer BE, Brookmeyer R, Choirat C, Dean NE, De Gruttola V, Ellenberg SS, Halloran ME, Hanley DF, Lee JK, Wang R, Scharfstein DO
Aggregating data from COVID-19 trials. Science. 2020 06 12; 368(6496):1198-1199.
Bovenberg J, Peloquin D, Bierer B, Barnes M, Knoppers BM
How to fix the GDPR's frustration of global biomedical research. Science. 2020 10 02; 370(6512):40-42.
How to fix the GDPR's frustration of global biomedical research.
Asch DA, Joffe S, Bierer BE, Greene SM, Lieu TA, Platt JE, Whicher D, Ahmed M, Platt R
Rethinking ethical oversight in the era of the learning health system. Healthc (Amst). 2020 Dec; 8(4):100462.
Rethinking ethical oversight in the era of the learning health system.
Bierer BE, White SA, Barnes JM, Gelinas L
Ethical Challenges in Clinical Research During the COVID-19 Pandemic. J Bioeth Inq. 2020 Dec; 17(4):717-722.
Ethical Challenges in Clinical Research During the COVID-19 Pandemic.
Raising standards for global data-sharing-Response. Science. 2021 01 08; 371(6525):134-135.
Raising standards for global data-sharing-Response.
Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research
Real-World Evidence: Understanding Sources of Variability Through Empirical Analysis. Value Health. 2021 01; 24(1):116-117.
Real-World Evidence: Understanding Sources of Variability Through Empirical Analysis.
Global Cooperation to Promote Clinical Research in Children
Meyer MN, Gelinas L, Bierer BE, Hull SC, Joffe S, Magnus D, Mohapatra S, Sharp RR, Spector-Bagdady K, Sugarman J, Wilfond BS, Lynch HF
An ethics framework for consolidating and prioritizing COVID-19 clinical trials. Clin Trials. 2021 04; 18(2):226-233.
An ethics framework for consolidating and prioritizing COVID-19 clinical trials.
Shamsoddin E, DeTora LM, Tovani-Palone MR, Bierer BE
Dental Care in Times of the COVID-19 Pandemic: A Review. Med Sci (Basel). 2021 02 19; 9(1).
Dental Care in Times of the COVID-19 Pandemic: A Review.
Justice, diversity, and research ethics review. Science. 2021 Mar 19; 371(6535):1209-1211.
Justice, diversity, and research ethics review.
Kasozi KI, Laudisoit A, Osuwat LO, Batiha GE, Al Omairi NE, Aigbogun E, Ninsiima HI, Usman IM, DeTora LM, MacLeod ET, Nalugo H, Crawley FP, Bierer BE, Mwandah DC, Kato CD, Kiyimba K, Ayikobua ET, Lillian L, Matama K, Nelly Mak SC, Onanyang D, Pius T, Nalumenya DP, Ssebuufu R, Rugambwa NO, Musoke GH, Bardosh K, Ochieng JJ, Ssempijja F, Kyamanywa P, Tumwine G, Alzahrani KJ, Welburn SC
A Descriptive-Multivariate Analysis of Community Knowledge, Confidence, and Trust in COVID-19 Clinical Trials among Healthcare Workers in Uganda. Vaccines (Basel). 2021 Mar 12; 9(3).
A Descriptive-Multivariate Analysis of Community Knowledge, Confidence, and Trust in COVID-19 Clinical Trials among Healthcare Workers in Uganda.
Gelinas L, Morrell W, White SA, Bierer BE
Online Research Participant Communication: Balancing Benefits and Risks. Ethics Hum Res. 2021 Jul; 43(4):2-10.
Online Research Participant Communication: Balancing Benefits and Risks.
Navigating the ethics of remote research data collection. Clin Trials. 2021 10; 18(5):606-614.
Navigating the ethics of remote research data collection.
Bierer BE, White SA, Gelinas L, Strauss DH
Fair payment and just benefits to enhance diversity in clinical research. J Clin Transl Sci. 2021; 5(1):e159.
Fair payment and just benefits to enhance diversity in clinical research.
Evaluating the frequency of English language requirements in clinical trial eligibility criteria: A systematic analysis using ClinicalTrials.gov. PLoS Med. 2021 09; 18(9):e1003758.
Evaluating the frequency of English language requirements in clinical trial eligibility criteria: A systematic analysis using ClinicalTrials.gov.
Kassis SB, White SA, Myers L, Trudeau C, Bierer BE
Advancing Health Literacy in Clinical Research: Clear Communications for Every Participant. NAM Perspect. 2019; 2019.
Advancing Health Literacy in Clinical Research: Clear Communications for Every Participant.
South A, Joharatnam-Hogan N, Purvis C, James EC, Diaz-Montana C, Cragg WJ, Tweed C, Macnair A, Sydes MR, Snowdon C, Gillies K, Isaacs T, Bierer BE, Copas AJ
Testing approaches to sharing trial results with participants: The Show RESPECT cluster randomised, factorial, mixed methods trial. PLoS Med. 2021 10; 18(10):e1003798.
Testing approaches to sharing trial results with participants: The Show RESPECT cluster randomised, factorial, mixed methods trial.
Seykora A, Coleman C, Rosenfeld SJ, Bierer BE, Lynch HF
Steps toward a System of IRB Precedent: Piloting Approaches to Summarizing IRB Decisions for Future Use. Ethics Hum Res. 2021 Nov; 43(6):2-18.
Steps toward a System of IRB Precedent: Piloting Approaches to Summarizing IRB Decisions for Future Use.
Demystifying Schrems II for the cross-border transfer of clinical research data. J Law Biosci. 2021 Jul-Dec; 8(2):lsab032.
Demystifying Schrems II for the cross-border transfer of clinical research data.
Bierer BE, Ne'eman A, DeCormier Plosky W, Strauss DH, Silverman BC, Stein MA
Integrating Supported Decision-Making into the Clinical Research Process. Am J Bioeth. 2021 11; 21(11):32-35.
Integrating Supported Decision-Making into the Clinical Research Process.
Tse T, White S, Gelinas L, Morrell W, Bierer B, Zarin DA
Characterization of Informed Consent Forms Posted on ClinicalTrials.gov. JAMA Netw Open. 2021 11 01; 4(11):e2135146.
Characterization of Informed Consent Forms Posted on ClinicalTrials.gov.
Spector-Bagdady K, Lynch HF, Bierer BE, Gelinas L, Hull SC, Magnus D, Meyer MN, Sharp RR, Sugarman J, Wilfond BS, Yearby R, Mohapatra S
Allocation of Opportunities to Participate in Clinical Trials during the Covid-19 Pandemic and Other Public Health Emergencies. Hastings Cent Rep. 2022 01; 52(1):51-58.
Allocation of Opportunities to Participate in Clinical Trials during the Covid-19 Pandemic and Other Public Health Emergencies.
Sonstein SA, Kim LP, Ichhpurani N, Padbidri R, White SA, Aldinger CE, Bierer BE
Incorporating Competencies Related to Project Management into the Joint Taskforce Core Competency Framework for Clinical Research Professionals. Ther Innov Regul Sci. 2022 03; 56(2):206-211.
Incorporating Competencies Related to Project Management into the Joint Taskforce Core Competency Framework for Clinical Research Professionals.
Di Stefano L, Ogburn EL, Ram M, Scharfstein DO, Li T, Khanal P, Baksh SN, McBee N, Gruber J, Gildea MR, Clark MR, Goldenberg NA, Bennani Y, Brown SM, Buckel WR, Clement ME, Mulligan MJ, O'Halloran JA, Rauseo AM, Self WH, Semler MW, Seto T, Stout JE, Ulrich RJ, Victory J, Bierer BE, Hanley DF, Freilich D
medRxiv : the preprint server for health sciences
Hydroxychloroquine/chloroquine for the treatment of hospitalized patients with COVID-19: An individual participant data meta-analysis. medRxiv. 2022 Aug 16.
Hydroxychloroquine/chloroquine for the treatment of hospitalized patients with COVID-19: An individual participant data meta-analysis.
Applying Civil Rights Law to Clinical Research: Title VI's Equal Access Mandate. J Law Med Ethics. 2022; 50(1):101-108.
Applying Civil Rights Law to Clinical Research: Title VI's Equal Access Mandate.
Sonstein SA, Samuels E, Aldinger C, White SA, Bierer BE
Self-assessed Competencies of Clinical Research Professionals and Recommendations for Further Education and Training. Ther Innov Regul Sci. 2022 07; 56(4):607-615.
Self-assessed Competencies of Clinical Research Professionals and Recommendations for Further Education and Training.
Friesen P, Gelinas L, Kirby A, Strauss DH, Bierer BE
IRBs and the Protection-Inclusion Dilemma: Finding a Balance. Am J Bioeth. 2023 06; 23(6):75-88.
IRBs and the Protection-Inclusion Dilemma: Finding a Balance.
Bierer BE, Meloney LG, Ahmed HR, White SA
Advancing the inclusion of underrepresented women in clinical research. Cell Rep Med. 2022 04 19; 3(4):100553.
Advancing the inclusion of underrepresented women in clinical research.
Strategies to optimize inclusion of women in multi-national clinical trials. Contemp Clin Trials. 2022 06; 117:106770.
Strategies to optimize inclusion of women in multi-national clinical trials.
Shachar C, Gerke S, Morrell W, Kirby A, Cohen IG, Bierer BE
When Is a Change Significant? The Update Problem of Apps in Medical and Behavioral Research. Ethics Hum Res. 2022 May; 44(3):2-11.
When Is a Change Significant? The Update Problem of Apps in Medical and Behavioral Research.
Kruse GR, Pelton-Cairns L, Taveras EM, Dargon-Hart S, Gundersen DA, Lee RM, Bierer BE, Lawlor E, LaRocque RC, Marcus JL, Davies ME, Emmons KM
Implementing expanded COVID-19 testing in Massachusetts community health centers through community partnerships: Protocol for an interrupted time series and stepped wedge study design. Contemp Clin Trials. 2022 07; 118:106783.
Implementing expanded COVID-19 testing in Massachusetts community health centers through community partnerships: Protocol for an interrupted time series and stepped wedge study design.
Baedorf Kassis S, Lu W, White SA, Shin IH, Park SH, Jeong YJ, Yao C, Ligibel J, Bierer BE
BMC complementary medicine and therapies
Developing and implementing a self-monitoring toolkit for a coordinated multinational randomized acupuncture trial. BMC Complement Med Ther. 2022 Jun 17; 22(1):161.
Developing and implementing a self-monitoring toolkit for a coordinated multinational randomized acupuncture trial.
Developing a consensus-driven, plain-language clinical research glossary for study participants and the clinical research community. J Clin Transl Sci. 2022; 6(1):e50.
Developing a consensus-driven, plain-language clinical research glossary for study participants and the clinical research community.
Crown W, Dahabreh IJ, Li X, Toh S, Bierer B
Can Observational Analyses of Routinely Collected Data Emulate Randomized Trials? Design and Feasibility of the Observational Patient Evidence for Regulatory Approval Science and Understanding Disease Project. Value Health. 2023 02; 26(2):176-184.
Can Observational Analyses of Routinely Collected Data Emulate Randomized Trials? Design and Feasibility of the Observational Patient Evidence for Regulatory Approval Science and Understanding Disease Project.
Silverman BC, Ne'eman A, Strauss DH, DeCormier Plosky W, Francis LP, Stein MA, Bierer BE
Supported decision-making can advance clinical research participation for people with disabilities. Nat Med. 2022 11; 28(11):2250-2253.
Supported decision-making can advance clinical research participation for people with disabilities.
Hydroxychloroquine/chloroquine for the treatment of hospitalized patients with COVID-19: An individual participant data meta-analysis. PLoS One. 2022; 17(9):e0273526.
Lu W, Giobbie-Hurder A, Tanasijevic A, Baedorf Kassis S, Park SH, Jeong YJ, Shin IH, Yao C, Jung HJ, Zhu Z, Bao C, Yang EM, Bierer BE, Ligibel JA
Acupuncture for hot flashes in hormone receptor-positive breast cancer, a coordinated multinational study: Rationale and design of the study protocol. Contemp Clin Trials. 2022 10; 121:106885.
Acupuncture for hot flashes in hormone receptor-positive breast cancer, a coordinated multinational study: Rationale and design of the study protocol.
DeCormier Plosky W, Ne'eman A, Silverman BC, Strauss DH, Francis LP, Stein MA, Bierer BE
Excluding People With Disabilities From Clinical Research: Eligibility Criteria Lack Clarity And Justification. Health Aff (Millwood). 2022 10; 41(10):1423-1432.
Excluding People With Disabilities From Clinical Research: Eligibility Criteria Lack Clarity And Justification.
An Externalist, Process-Based Approach to Supported Decision-Making. Am J Bioeth. 2022 10; 22(10):55-58.
An Externalist, Process-Based Approach to Supported Decision-Making.
Gelinas L, Strauss DH, Chen Y, Ahmed HR, Kirby A, Friesen P, Bierer BE
Journal of empirical research on human research ethics : JERHRE
Protecting the Vulnerable and Including the Under-Represented: IRB Practices and Attitudes. J Empir Res Hum Res Ethics. 2023 Feb-Apr; 18(1-2):58-68.
Protecting the Vulnerable and Including the Under-Represented: IRB Practices and Attitudes.
Morrell W, Gelinas L, Zarin D, Bierer BE
Ensuring the Scientific Value and Feasibility of Clinical Trials: A Qualitative Interview Study. AJOB Empir Bioeth. 2023 Apr-Jun; 14(2):99-110.
Ensuring the Scientific Value and Feasibility of Clinical Trials: A Qualitative Interview Study.
Joffe S, Allen AJ, Davis JM, Koppelman E, Kornetsky SZ, Ku GMV, Miller VA, Preston J, Shah LD, Bierer BE
Establishing a global regulatory floor for children's decisions about participation in clinical research. Pediatr Res. 2023 08; 94(2):462-465.
Establishing a global regulatory floor for children's decisions about participation in clinical research.
Green JM, Goodman P, Kirby A, Cobb N, Bierer BE
Implementation of single IRB review for multisite human subjects research: Persistent challenges and possible solutions. J Clin Transl Sci. 2023; 7(1):e99.
Implementation of single IRB review for multisite human subjects research: Persistent challenges and possible solutions.
Gelinas L, Hutchinson N, Zarin DA, Bierer BE
How to limit uninformative trials: Results from a Delphi working group. Med. 2023 04 14; 4(4):226-232.
How to limit uninformative trials: Results from a Delphi working group.
Data visualization explorer: A tool for participant representation in pivotal trials of FDA-approved medicinal products. Patterns (N Y). 2023 May 12; 4(5):100713.
Data visualization explorer: A tool for participant representation in pivotal trials of FDA-approved medicinal products.
Terms and conditions apply: an ethical analysis of mobile health user agreements in research. J Law Biosci. 2023 Jul-Dec; 10(2):lsad021.
Terms and conditions apply: an ethical analysis of mobile health user agreements in research.
Hutchinson N, Gelinas L, Zarin D, Bierer BE
Disclosure of Possible Trial Termination to Participants of Interventional Clinical Trials. JAMA. 2023 04 04; 329(13):1116-1117.
Disclosure of Possible Trial Termination to Participants of Interventional Clinical Trials.
Shen FX, Baum ML, Martinez-Martin N, Miner AS, Abraham M, Brownstein CA, Cortez N, Evans BJ, Germine LT, Glahn DC, Grady C, Holm IA, Hurley EA, Kimble S, Lázaro-Muñoz G, Leary K, Marks M, Monette PJ, Onnela JP, O'Rourke PP, Rauch SL, Shachar C, Sen S, Vahia I, Vassy JL, Baker JT, Bierer BE, Silverman BC
Returning Individual Research Results from Digital Phenotyping in Psychiatry. Am J Bioeth. 2024 Feb; 24(2):69-90.
Returning Individual Research Results from Digital Phenotyping in Psychiatry.
Emmons KM, Mendez S, Lee RM, Erani D, Mascioli L, Abreu M, Adams S, Daly J, Bierer BE
Data sharing in the context of community-engaged research partnerships. Soc Sci Med. 2023 05; 325:115895.
Data sharing in the context of community-engaged research partnerships.
Di Stefano L, Ram M, Scharfstein DO, Li T, Khanal P, Baksh SN, McBee N, Bengtson CD, Gadomski A, Geriak M, Puskarich MA, Salathe MA, Schutte AE, Tignanelli CJ, Victory J, Bierer BE, Hanley DF, Freilich DA
Losartan in hospitalized patients with COVID-19 in North America: An individual participant data meta-analysis. Medicine (Baltimore). 2023 Jun 09; 102(23):e33904.
Losartan in hospitalized patients with COVID-19 in North America: An individual participant data meta-analysis.
South A, Bailey J, Bierer BE, Burnett E, Cragg WJ, Diaz-Montana C, Gillies K, Isaacs T, Joharatnam-Hogan N, Snowdon C, Sydes MR, Copas AJ
Site staff perspectives on communicating trial results to participants: Cost and feasibility results from the Show RESPECT cluster randomised, factorial, mixed-methods trial. Clin Trials. 2023 12; 20(6):649-660.
Site staff perspectives on communicating trial results to participants: Cost and feasibility results from the Show RESPECT cluster randomised, factorial, mixed-methods trial.
Marrie RA, Chataway J, Bierer BE, Finlayson M, Martinez-Lapiscina EH, Panagoulias J, Sormani MP, Williams MJ, Amezcua L
Multiple sclerosis (Houndmills, Basingstoke, England)
Enhancing diversity of clinical trial populations in multiple sclerosis. Mult Scler. 2023 08; 29(9):1174-1185.
Enhancing diversity of clinical trial populations in multiple sclerosis.
Review of diversity, equity, and inclusion by ethics committees: A Delphi consensus statement. Med. 2023 08 11; 4(8):497-504.
Review of diversity, equity, and inclusion by ethics committees: A Delphi consensus statement.
The Unresolved Challenge of Triage. JAMA Netw Open. 2023 08 01; 6(8):e2329676.
Acknowledging Complexity and Reimagining IRBs: A Reply to Discussions of the Protection-Inclusion Dilemma. Am J Bioeth. 2023 09; 23(9):W1-W8.
Acknowledging Complexity and Reimagining IRBs: A Reply to Discussions of the Protection-Inclusion Dilemma.
Defining "recklessness" in research misconduct proceedings. Account Res. 2025 02; 32(2):120-142.
Defining "recklessness" in research misconduct proceedings.
Gelinas L, Morrell W, Tse T, Glazier A, Zarin DA, Bierer BE
Characterization of key information sections in informed consent forms posted on ClinicalTrials.gov. J Clin Transl Sci. 2023; 7(1):e185.
Characterization of key information sections in informed consent forms posted on ClinicalTrials.gov.
Deprioritization of Ongoing Clinical Trials. Ethics Hum Res. 2023 Sep-Oct; 45(5):27-33.
Deprioritization of Ongoing Clinical Trials.
Sonstein SA, Silva H, Jones CT, Bierer BE
Education and training of clinical research professionals and the evolution of the Joint Task Force for Clinical Trial Competency. Front Pharmacol. 2024; 15:1291675.
Education and training of clinical research professionals and the evolution of the Joint Task Force for Clinical Trial Competency.
Ethical Considerations in Decentralized Clinical Trials. J Bioeth Inq. 2023 12; 20(4):711-718.
Ethical Considerations in Decentralized Clinical Trials.
Wright K, DeCormier Plosky W, Ahmed HR, White SA, Bierer BE
First, do no harm: a global perspective on diversity and inclusion in clinical trials. Nat Rev Drug Discov. 2024 07; 23(7):481-482.
First, do no harm: a global perspective on diversity and inclusion in clinical trials.
Torres CH, Kassis SB, Sayeed S, Bierer BE, Emmons KM
A Federally Qualified Health Center-led Ethics & Equity Framework & Workflow Checklist: An Invited Commentary in Response to a Relational Public Health Framing of FQHCs During COVID-19. J Law Med Ethics. 2024; 52(1):41-44.
A Federally Qualified Health Center-led Ethics & Equity Framework & Workflow Checklist: An Invited Commentary in Response to a Relational Public Health Framing of FQHCs During COVID-19.
Sofi-Mahmudi A, Shamsoddin E, DeTora LM, Bierer BE, Ekmekci PE, Folayan MO, Lii CS, Tovani-Palone MR, Crawley FP
An investigation into gender distributions in scholarly publications among dental faculty members in Iran. PLoS One. 2024; 19(6):e0300698.
An investigation into gender distributions in scholarly publications among dental faculty members in Iran.
Proposed Increases in Government Authority Over Research Misconduct Proceedings. JAMA. 2024 07 16; 332(3):193-194.
Proposed Increases in Government Authority Over Research Misconduct Proceedings.
Lu W, Giobbie-Hurder A, Tanasijevic A, Kassis SB, Park SH, Jeong YJ, Shin IH, Yao C, Jung HJ, Zhu Z, Bao C, Bao T, Yang E, Bierer BE, Ligibel JA
Acupuncture for hot flashes in hormone receptor-positive breast cancer: A pooled analysis of individual patient data from parallel randomized trials. Cancer. 2024 Sep 15; 130(18):3219-3228.
Acupuncture for hot flashes in hormone receptor-positive breast cancer: A pooled analysis of individual patient data from parallel randomized trials.
Assistant Professor of Health Policy and Management
South A, Snowdon C, Burnett E, Bierer BE, Gillies K, Isaacs T, Sydes MR
The SHOW RESPECT adaptable framework of considerations for planning how to share trial results with participants, based on qualitative findings from trial participants and site staff. Trials. 2024 Jul 10; 25(1):467.
The SHOW RESPECT adaptable framework of considerations for planning how to share trial results with participants, based on qualitative findings from trial participants and site staff.
Jones CT, Johnson E, Bierer BE, Snyder DC, Smith HA, Akuffo E, Sonstein S
Editorial: Building the clinical research workforce: challenges, capacities and competencies. Front Pharmacol. 2024; 15:1446908.
Editorial: Building the clinical research workforce: challenges, capacities and competencies.
The PubPeer conundrum: Administrative challenges in research misconduct proceedings. Account Res. 2025 Nov; 32(8):1369-1387.
The PubPeer conundrum: Administrative challenges in research misconduct proceedings.
The Promise and Perils of Diversity Action Plans for Clinical Trials. JAMA. 2024 Dec 03; 332(21):1787-1788.
The Promise and Perils of Diversity Action Plans for Clinical Trials.
Biomedical innovation in academic institutions: mitigating conflict of interest. Sci Transl Med. 2011 Sep 14; 3(100):100cm26.
Biomedical innovation in academic institutions: mitigating conflict of interest.
The Journal of bone and joint surgery. American volume
The Role of Institutional Review Boards in Improving the Inclusion of Sex and Gender as Variables in Clinical Research. J Bone Joint Surg Am. 2024 Sep 18; 106(18):1718-1722.
The Role of Institutional Review Boards in Improving the Inclusion of Sex and Gender as Variables in Clinical Research.
Declaration of Helsinki-Revisions for the 21st Century. JAMA. 2025 Jan 07; 333(1):18-19.
Declaration of Helsinki-Revisions for the 21st Century.
Bierer BE, Koppelman E, Croker AK, Hosseinzadeh S, Hovinga C, Joffe S, McMillan G, Nelson R, Bucci-Rechtweg C
Engaging children and adolescents in the design and conduct of paediatric research. Front Pediatr. 2024; 12:1481754.
Engaging children and adolescents in the design and conduct of paediatric research.
Kuaban A, Croker AK, Keefer J, Valentino LA, Bierer BE, Boateng S, DiMichele D, Fogarty P, Gibson CM, Hood AM, Hubbard L, Isgrò A, Knobe K, Lake L, Martin I, Reid M, Roberts JC, Tomlinson W, Tunji-Ajayi L, Van Spall HGC, Voltz-Girolt C, Wheeler AP, Mast AE, Seremetis S
The roadmap to integrate diversity, equity, and inclusion in hematology clinical trials: an American Society of Hematology initiative. Blood Adv. 2025 Feb 25; 9(4):687-695.
The roadmap to integrate diversity, equity, and inclusion in hematology clinical trials: an American Society of Hematology initiative.
Determining the Optimal Pathway for Clinical Trial Management at Montefiore/Einstein
Muthukumar AV, Shah KM, Glynn RJ, Bierer BE
Persistent exclusion of non-English speakers in Pediatric research: a national analysis using ClinicalTrials.gov. Pediatr Res. 2025 Sep; 98(3):839-843.
Persistent exclusion of non-English speakers in Pediatric research: a national analysis using ClinicalTrials.gov.
Mello MM, Francer JK, Wilenzick M, Teden P, Bierer BE, Barnes M
Preparing for responsible sharing of clinical trial data. N Engl J Med. 2013 Oct 24; 369(17):1651-8.
Preparing for responsible sharing of clinical trial data.
Jaffe N, Caron M, Walsh L, Bierer B, Barnes M
Defamation Claims Arising from Research Misconduct Cases: Best Practices for Institutions. J Law Med Ethics. 2025 Apr 21; 1-8.
Defamation Claims Arising from Research Misconduct Cases: Best Practices for Institutions.
Anderson AM, Martin RA, DeCormier Plosky W, Ned L, Swenor BK, Bailie J, Mathias K, Maggo JK, Omino MA, Russell AM, Lawson AMM, Brown AE, Bierer BE, Shariq S, Mwifadhi M, Deane KHO, Philip S, Shepherd V, Walsh NE, McHugh GA
A global call to action for disability inclusion in health research. Nat Med. 2025 May; 31(5):1399-1403.
A global call to action for disability inclusion in health research.
Barksdale EKS, Selig W, DeCormier Plosky W, Miller E, McDonough K, Backler C, George E, Fleury ME, Taylor MJ, Pankevich DE, Murphy J, Hermann K, Davis LA, DeCotiis G, Gonzalez-Cerimele C, Cook C, Shaw S, Gelinas L, Dornsife DL, Bierer BE, Gerber DE
Financial Toxicity in Cancer Clinical Trials: An Issue in Need of Clarity and Solutions. J Clin Oncol. 2025 Jul 10; 43(20):2231-2238.
Financial Toxicity in Cancer Clinical Trials: An Issue in Need of Clarity and Solutions.
Thornton L, Cohen D, Barnes M, Bierer BE
Managing Multi-Institutional Jurisdiction in Cases of Research Misconduct. J Law Med Ethics. 2025 Apr 28; 1-6.
Managing Multi-Institutional Jurisdiction in Cases of Research Misconduct.
Benefits that Offset Research Risks and Burdens are Qualitatively Different. Am J Bioeth. 2025 May; 25(5):78-80.
Benefits that Offset Research Risks and Burdens are Qualitatively Different.
Nguyen E, Appiah D, Ne'eman A, Shi M, Bierer BE, DeCormier Plosky W, Resnik DB
An Analysis of Institutional Review Board Policies for Enrollment of Adults with Impaired or Uncertain Decision-Making Capacity. J Empir Res Hum Res Ethics. 2025 Jul; 20(3):123-130.
An Analysis of Institutional Review Board Policies for Enrollment of Adults with Impaired or Uncertain Decision-Making Capacity.
Byiringiro S, Garcia JK, Farrell N, Ogungbe B, Barsha RAA, Miller HN, Whitaker E, Wang P, Rosa WE, Bierer BE, Himmelfarb CR, Michos ED, De Lombaert K, Berdichesky M, Busque S, Palaniappan L, Lewis E, Rodriguez F, Valantine H
Advocating for collaboration among key partners to promote diversity in clinical studies amid policy challenges in the United States of America. Trials. 2025 Apr 02; 26(1):117.
Advocating for collaboration among key partners to promote diversity in clinical studies amid policy challenges in the United States of America.
Albert-Rozenberg D, Peloquin D, Liss J, Hanson E, Bierer BE
Assessing Federal Policies to Reduce Economic Barriers to Clinical Trial Enrollment. J Law Med Ethics. 2025 May 23; 1-10.
Assessing Federal Policies to Reduce Economic Barriers to Clinical Trial Enrollment.
Harvard Catalyst | The Clinical Translational Science Center IND/IDE Consult Service: providing an IND/IDE consult service in a decentralized network of academic healthcare centers. Clin Transl Sci. 2014 Apr; 7(2):150-5.
Harvard Catalyst | The Clinical Translational Science Center IND/IDE Consult Service: providing an IND/IDE consult service in a decentralized network of academic healthcare centers.
Walsh L, Caron M, Lye CT, Barnes M, Bierer BE
Maintaining the Integrity of the Biomedical Research Record Through Timely, Appropriate Corrective Action. J Law Med Ethics. 2025; 53(3):486-490.
Maintaining the Integrity of the Biomedical Research Record Through Timely, Appropriate Corrective Action.
Zhang J, Bierer BE, Van Spall HGC, Liu Y, Bai X, Thabane L, Lip GYH, Sun X, Moher D, Li G
Practice of data sharing plans in clinical trial registrations and concordance between registered and published data sharing plans: a cross-sectional study. BMC Med. 2025 Sep 01; 23(1):510.
Practice of data sharing plans in clinical trial registrations and concordance between registered and published data sharing plans: a cross-sectional study.
Lye CT, Caron MM, Walsh L, Bierer BE, Barnes M
Disparate data retention standards in biomedical research. Account Res. 2026 May; 33(4):2543884.
Disparate data retention standards in biomedical research.
Hutchinson N, Otterman LS, Bain PA, Koppelman E, Bierer BE
International journal of technology assessment in health care
A scoping review of challenges in pediatric health technology assessments with a focus on pharmaceutical interventions. Int J Technol Assess Health Care. 2025 Oct 16; 41(1):e79.
A scoping review of challenges in pediatric health technology assessments with a focus on pharmaceutical interventions.
Chapman CR, Glazier A, Berbic E, Bierer BE
Characteristics of long-term follow-up studies for gene therapies registered on ClinicalTrials.gov. Gene Ther. 2025 Oct 22.
Characteristics of long-term follow-up studies for gene therapies registered on ClinicalTrials.gov.
Chapman CR, Shaikh M, Glazier A, Creamer A, Bierer BE
Ethical, Legal, and Social Issues (ELSI) in Human Somatic Gene Therapy Clinical Research: A Scoping Review. Hum Gene Ther. 2025 Nov; 36(21-22):1387-1404.
Ethical, Legal, and Social Issues (ELSI) in Human Somatic Gene Therapy Clinical Research: A Scoping Review.
Glazier A, DeCormier Plosky W, Bierer BE
Disclosure of Pregnancy-Related Privacy Risks in Clinical Research Post-Dobbs. NEJM Evid. 2026 Mar; 5(3):EVIDra2500239.
Disclosure of Pregnancy-Related Privacy Risks in Clinical Research Post-Dobbs.
Research misconduct involving noncompliance in human subjects research supported by the public health service: reconciling separate regulatory systems. Hastings Cent Rep. 2014 Jul-Aug; 44(4 Spec No):S2-26.
Research misconduct involving noncompliance in human subjects research supported by the public health service: reconciling separate regulatory systems.
Winkler SJ, Cagliero E, Witte E, Bierer BE
A distributed model: redefining a robust research subject advocacy program at the Harvard Clinical and Translational Science Center. Clin Transl Sci. 2014 Aug; 7(4):329-35.
A distributed model: redefining a robust research subject advocacy program at the Harvard Clinical and Translational Science Center.
The Harvard Catalyst Common Reciprocal IRB Reliance Agreement: an innovative approach to multisite IRB review and oversight. Clin Transl Sci. 2015 Feb; 8(1):57-66.
The Harvard Catalyst Common Reciprocal IRB Reliance Agreement: an innovative approach to multisite IRB review and oversight.
Compliance with results reporting at ClinicalTrials.gov. N Engl J Med. 2015 06 11; 372(24):2370.
Compliance with results reporting at ClinicalTrials.gov.
Borus JF, Alexander EK, Bierer BE, Bringhurst FR, Clark C, Klanica KE, Stewart EC, Friedman LS
Academic medicine : journal of the Association of American Medical Colleges
The Education Review Board: A Mechanism for Managing Potential Conflicts of Interest in Medical Education. Acad Med. 2015 Dec; 90(12):1611-7.
The Education Review Board: A Mechanism for Managing Potential Conflicts of Interest in Medical Education.
Confronting Biospecimen Exceptionalism in Proposed Revisions to the Common Rule. Hastings Cent Rep. 2016 Jan-Feb; 46(1):4-5.
Confronting Biospecimen Exceptionalism in Proposed Revisions to the Common Rule.
Standards for Clinical Research: Keeping Pace With the Technology of the Future. Circulation. 2016 Mar 01; 133(9):823-5.
Standards for Clinical Research: Keeping Pace With the Technology of the Future.
Li RH, Wacholtz MC, Barnes M, Boggs L, Callery-D'Amico S, Davis A, Digilova A, Forster D, Heffernan K, Luthin M, Lynch HF, McNair L, Miller JE, Murphy J, Van Campen L, Wilenzick M, Wolf D, Woolston C, Aldinger C, Bierer BE
Incorporating ethical principles into clinical research protocols: a tool for protocol writers and ethics committees. J Med Ethics. 2016 Apr; 42(4):229-34.
Incorporating ethical principles into clinical research protocols: a tool for protocol writers and ethics committees.
A Global, Neutral Platform for Sharing Trial Data. N Engl J Med. 2016 Jun 23; 374(25):2411-3.
A Global, Neutral Platform for Sharing Trial Data.
MECHANISMS OF IMMUNOSUPPRESSION BY FK506
Short-Term Research Education Program to Increase Diversity in Health-Related Res
Cellular and Molecular Studies of Bone Marrow Transplant
Centers For Clinical Research on TransplantaTION
INTERACTION OF CD-2 WITH LFA-3 IN T CELL ACTIVATION
Short-Term Training in Cardiovascular Research
Sagoo JK, Fruman DA, Wesselborg S, Walsh CT, Bierer BE
Competitive inhibition of calcineurin phosphatase activity by its autoinhibitory domain. Biochem J. 1996 Dec 15; 320 ( Pt 3):879-84.
Competitive inhibition of calcineurin phosphatase activity by its autoinhibitory domain.
Interleukin 2 stimulation of p70 S6 kinase activity is inhibited by the immunosuppressant rapamycin. Proc Natl Acad Sci U S A. 1992 Aug 15; 89(16):7571-5.
Interleukin 2 stimulation of p70 S6 kinase activity is inhibited by the immunosuppressant rapamycin.
Calcium- and FK506-independent interaction between the immunophilin FKBP51 and calcineurin. J Cell Biochem. 2002; 84(3):460-71.
Calcium- and FK506-independent interaction between the immunophilin FKBP51 and calcineurin.
Lehmann LE, Guinan EC, Halpern SL, Donovan MJ, Bierer BE, Parsons SK
Isolated testicular relapse in an adolescent 5 years following allogeneic bone marrow transplantation for acute myelogenous leukemia. Bone Marrow Transplant. 1997 Apr; 19(8):849-51.
Isolated testicular relapse in an adolescent 5 years following allogeneic bone marrow transplantation for acute myelogenous leukemia.
Fruman DA, Mather PE, Burakoff SJ, Bierer BE
Correlation of calcineurin phosphatase activity and programmed cell death in murine T cell hybridomas. Eur J Immunol. 1992 Oct; 22(10):2513-7.
Correlation of calcineurin phosphatase activity and programmed cell death in murine T cell hybridomas.
When clinical trials compete: prioritising study recruitment. J Med Ethics. 2017 12; 43(12):803-809.
When clinical trials compete: prioritising study recruitment.
Hahn WC, Rosenstein Y, Calvo V, Burakoff SJ, Bierer BE
A distinct cytoplasmic domain of CD2 regulates ligand avidity and T-cell responsiveness to antigen. Proc Natl Acad Sci U S A. 1992 Aug 01; 89(15):7179-83.
A distinct cytoplasmic domain of CD2 regulates ligand avidity and T-cell responsiveness to antigen.
Gelinas L, Pierce R, Winkler S, Cohen IG, Lynch HF, Bierer BE
Using Social Media as a Research Recruitment Tool: Ethical Issues and Recommendations. Am J Bioeth. 2017 Mar; 17(3):3-14.
Using Social Media as a Research Recruitment Tool: Ethical Issues and Recommendations.
Ouyang Y, Virasch N, Hao P, Aubrey MT, Mukerjee N, Bierer BE, Freed BM
The Journal of allergy and clinical immunology
Suppression of human IL-1beta, IL-2, IFN-gamma, and TNF-alpha production by cigarette smoke extracts. J Allergy Clin Immunol. 2000 Aug; 106(2):280-7.
Suppression of human IL-1beta, IL-2, IFN-gamma, and TNF-alpha production by cigarette smoke extracts.
T cell receptors: adhesion and signaling. Adv Cancer Res. 1991; 56:49-76.
T cell receptors: adhesion and signaling.
Cancedda C, Riviello R, Wilson K, Scott KW, Tuteja M, Barrow JR, Hedt-Gauthier B, Bukhman G, Scott J, Milner D, Raviola G, Weissman B, Smith S, Nuthulaganti T, McClain CD, Bierer BE, Farmer PE, Becker AE, Binagwaho A, Rhatigan J, Golan DE
Building Workforce Capacity Abroad While Strengthening Global Health Programs at Home: Participation of Seven Harvard-Affiliated Institutions in a Health Professional Training Initiative in Rwanda. Acad Med. 2017 05; 92(5):649-658.
Building Workforce Capacity Abroad While Strengthening Global Health Programs at Home: Participation of Seven Harvard-Affiliated Institutions in a Health Professional Training Initiative in Rwanda.
Antin JH, Bierer BE, Smith BR, Guinan EC, Provost MM, Ferrara J, Macklis RM, Tarbell NJ, Blythman H, Bouloux C
Depletion of bone marrow T-lymphocytes with an anti-CD5 monoclonal immunotoxin (ST-1 immunotoxin): effective prophylaxis for graft-versus-host disease. Prog Clin Biol Res. 1990; 333:207-15.
Depletion of bone marrow T-lymphocytes with an anti-CD5 monoclonal immunotoxin (ST-1 immunotoxin): effective prophylaxis for graft-versus-host disease.
Kivens WJ, Hunt SW, Mobley JL, Zell T, Dell CL, Bierer BE, Shimizu Y
Identification of a proline-rich sequence in the CD2 cytoplasmic domain critical for regulation of integrin-mediated adhesion and activation of phosphoinositide 3-kinase. Mol Cell Biol. 1998 Sep; 18(9):5291-307.
Identification of a proline-rich sequence in the CD2 cytoplasmic domain critical for regulation of integrin-mediated adhesion and activation of phosphoinositide 3-kinase.
Jin YJ, Albers MW, Lane WS, Bierer BE, Schreiber SL, Burakoff SJ
Molecular cloning of a membrane-associated human FK506- and rapamycin-binding protein, FKBP-13. Proc Natl Acad Sci U S A. 1991 Aug 01; 88(15):6677-81.
Molecular cloning of a membrane-associated human FK506- and rapamycin-binding protein, FKBP-13.
Bierer BE, Jin YJ, Fruman DA, Calvo V, Burakoff SJ
FK 506 and rapamycin: molecular probes of T-lymphocyte activation. Transplant Proc. 1991 Dec; 23(6):2850-5.
FK 506 and rapamycin: molecular probes of T-lymphocyte activation.
Institutions as an ethical locus of research prioritisation. J Med Ethics. 2017 12; 43(12):816-818.
Institutions as an ethical locus of research prioritisation.
Morley SC, Sung J, Sun GP, Martelli MP, Bunnell SC, Bierer BE
Gelsolin overexpression alters actin dynamics and tyrosine phosphorylation of lipid raft-associated proteins in Jurkat T cells. Mol Immunol. 2007 Mar; 44(9):2469-80.
Gelsolin overexpression alters actin dynamics and tyrosine phosphorylation of lipid raft-associated proteins in Jurkat T cells.
Data Authorship as an Incentive to Data Sharing. N Engl J Med. 2017 04 27; 376(17):1684-1687.
Data Authorship as an Incentive to Data Sharing.
Dunussi-Joannopoulos K, Dranoff G, Weinstein HJ, Ferrara JL, Bierer BE, Croop JM
Gene immunotherapy in murine acute myeloid leukemia: granulocyte-macrophage colony-stimulating factor tumor cell vaccines elicit more potent antitumor immunity compared with B7 family and other cytokine vaccines. Blood. 1998 Jan 01; 91(1):222-30.
Gene immunotherapy in murine acute myeloid leukemia: granulocyte-macrophage colony-stimulating factor tumor cell vaccines elicit more potent antitumor immunity compared with B7 family and other cytokine vaccines.
Cristillo AD, Xiao X, Campbell-Malone R, Dimitrov DS, Bierer BE
Differences between CEM and human peripheral blood T lymphocytes in cAMP-dependent HIV viral fusion and CXCR4 expression. Exp Mol Pathol. 2002 Aug; 73(1):9-18.
Differences between CEM and human peripheral blood T lymphocytes in cAMP-dependent HIV viral fusion and CXCR4 expression.
Martelli MP, Lin H, Zhang W, Samelson LE, Bierer BE
Signaling via LAT (linker for T-cell activation) and Syk/ZAP70 is required for ERK activation and NFAT transcriptional activation following CD2 stimulation. Blood. 2000 Sep 15; 96(6):2181-90.
Signaling via LAT (linker for T-cell activation) and Syk/ZAP70 is required for ERK activation and NFAT transcriptional activation following CD2 stimulation.
Gelinas L, Pierce R, Winkler S, Cohen G, Lynch HF, Bierer BE
Nonexceptionalism, Research Risks, and Social Media: Response to Open Peer Commentaries on "Using Social Media as a Research Recruitment Tool: Ethical Issues and Recommendations". Am J Bioeth. 2017 05; 17(5):W1-W3.
Nonexceptionalism, Research Risks, and Social Media: Response to Open Peer Commentaries on "Using Social Media as a Research Recruitment Tool: Ethical Issues and Recommendations".
Trede NS, Warwick AB, Rosoff PM, Rohrer R, Bierer BE, Guinan E
Tacrolimus (FK506) in allogeneic bone marrow transplantation for severe aplastic anemia following orthotopic liver transplantation. Bone Marrow Transplant. 1997 Aug; 20(3):257-60.
Tacrolimus (FK506) in allogeneic bone marrow transplantation for severe aplastic anemia following orthotopic liver transplantation.
Ballen KK, Gilliland DG, Guinan EC, Hsieh CC, Parsons SK, Rimm IJ, Ferrara JL, Bierer BE, Weinstein HJ, Antin JH
Bone marrow transplantation for therapy-related myelodysplasia: comparison with primary myelodysplasia. Bone Marrow Transplant. 1997 Nov; 20(9):737-43.
Bone marrow transplantation for therapy-related myelodysplasia: comparison with primary myelodysplasia.
T cell regulation of p62(dok) (Dok1) association with Crk-L. J Biol Chem. 2001 Dec 07; 276(49):45654-61.
T cell regulation of p62(dok) (Dok1) association with Crk-L.
Hahn WC, Rosenstein Y, Burakoff SJ, Bierer BE
Interaction of CD2 with its ligand lymphocyte function-associated antigen-3 induces adenosine 3',5'-cyclic monophosphate production in T lymphocytes. J Immunol. 1991 Jul 01; 147(1):14-21.
Interaction of CD2 with its ligand lymphocyte function-associated antigen-3 induces adenosine 3',5'-cyclic monophosphate production in T lymphocytes.
Cristillo AD, Nie L, Macri MJ, Bierer BE
Cloning and characterization of N4WBP5A, an inducible, cyclosporine-sensitive, Nedd4-binding protein in human T lymphocytes. J Biol Chem. 2003 Sep 05; 278(36):34587-97.
Cloning and characterization of N4WBP5A, an inducible, cyclosporine-sensitive, Nedd4-binding protein in human T lymphocytes.
Posey SC, Martelli MP, Azuma T, Kwiatkowski DJ, Bierer BE
Failure of gelsolin overexpression to regulate lymphocyte apoptosis. Blood. 2000 Jun 01; 95(11):3483-8.
Failure of gelsolin overexpression to regulate lymphocyte apoptosis.
The involvement of the proto-oncogene p120 c-Cbl and ZAP-70 in CD2-mediated T cell activation. Int Immunol. 2001 Jan; 13(1):13-22.
The involvement of the proto-oncogene p120 c-Cbl and ZAP-70 in CD2-mediated T cell activation.
T cell signal transduction and the role of CD7 in costimulation. Immunol Res. 2001; 24(1):31-52.
T cell signal transduction and the role of CD7 in costimulation.
Winston DJ, Antin JH, Wolff SN, Bierer BE, Small T, Miller KB, Linker C, Kaizer H, Lazarus HM, Petersen FB, Cowan MJ, Ho WG, Wingard JR, Schiller GJ, Territo MC, Jiao J, Petrarca MA, Tonetta SA
A multicenter, randomized, double-blind comparison of different doses of intravenous immunoglobulin for prevention of graft-versus-host disease and infection after allogeneic bone marrow transplantation. Bone Marrow Transplant. 2001 Jul; 28(2):187-96.
A multicenter, randomized, double-blind comparison of different doses of intravenous immunoglobulin for prevention of graft-versus-host disease and infection after allogeneic bone marrow transplantation.
Cristillo AD, Highbarger HC, Dewar RL, Dimitrov DS, Golding H, Bierer BE
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Up-regulation of HIV coreceptor CXCR4 expression in human T lymphocytes is mediated in part by a cAMP-responsive element. FASEB J. 2002 Mar; 16(3):354-64.
Up-regulation of HIV coreceptor CXCR4 expression in human T lymphocytes is mediated in part by a cAMP-responsive element.
Wheeler C, Eickhoff C, Elias A, Ibrahim J, Ayash L, McCauley M, Mauch P, Schwartz G, Eder JP, Mazanet R, Ferrara J, Rimm IJ, Guinan E, Bierer B, Gilliland G, Churchill WH, Ault K, Parsons S, Antman K, Schnipper L, Tepler I, Gaynes L, Frei E, Kadin M, Antin J
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation
High-dose cyclophosphamide, carmustine, and etoposide with autologous transplantation in Hodgkin's disease: a prognostic model for treatment outcomes. Biol Blood Marrow Transplant. 1997 Jun; 3(2):98-106.
High-dose cyclophosphamide, carmustine, and etoposide with autologous transplantation in Hodgkin's disease: a prognostic model for treatment outcomes.
Molecular cloning of a 25-kDa high affinity rapamycin binding protein, FKBP25. J Biol Chem. 1992 Jun 05; 267(16):10942-5.
Molecular cloning of a 25-kDa high affinity rapamycin binding protein, FKBP25.
Actin stabilization by jasplakinolide enhances apoptosis induced by cytokine deprivation. J Biol Chem. 1999 Feb 12; 274(7):4259-65.
Actin stabilization by jasplakinolide enhances apoptosis induced by cytokine deprivation.
CD28/CTLA-4 and CD80/CD86 families: signaling and function. Immunol Res. 1999; 19(1):1-24.
CD28/CTLA-4 and CD80/CD86 families: signaling and function.
Virella G, Rugeles MT, Hyman B, La Via M, Goust JM, Frankis M, Bierer BE
The interaction of CD2 with its LFA-3 ligand expressed by autologous erythrocytes results in enhancement of B cell responses. Cell Immunol. 1988 Oct 15; 116(2):308-19.
The interaction of CD2 with its LFA-3 ligand expressed by autologous erythrocytes results in enhancement of B cell responses.
T-lymphocyte coactivator molecules. Curr Opin Hematol. 2001 Jan; 8(1):5-11.
Weingart SN, Price J, Duncombe D, Connor M, Conley K, Conlin GJ, Sullivan AM, Powell M, Ponte PR, Bierer BE
Enhancing safety reporting in adult ambulatory oncology with a clinician champion: a practice innovation. J Nurs Care Qual. 2009 Jul-Sep; 24(3):203-10.
Enhancing safety reporting in adult ambulatory oncology with a clinician champion: a practice innovation.
Park JK, Rosenstein YJ, Remold-O'Donnell E, Bierer BE, Rosen FS, Burakoff SJ
Enhancement of T-cell activation by the CD43 molecule whose expression is defective in Wiskott-Aldrich syndrome. Nature. 1991 Apr 25; 350(6320):706-9.
Enhancement of T-cell activation by the CD43 molecule whose expression is defective in Wiskott-Aldrich syndrome.
Kaye RE, Fruman DA, Bierer BE, Albers MW, Zydowsky LD, Ho SI, Jin YJ, Castells MC, Schreiber SL, Walsh CT
Effects of cyclosporin A and FK506 on Fc epsilon receptor type I-initiated increases in cytokine mRNA in mouse bone marrow-derived progenitor mast cells: resistance to FK506 is associated with a deficiency in FK506-binding protein FKBP12. Proc Natl Acad Sci U S A. 1992 Sep 15; 89(18):8542-6.
Effects of cyclosporin A and FK506 on Fc epsilon receptor type I-initiated increases in cytokine mRNA in mouse bone marrow-derived progenitor mast cells: resistance to FK506 is associated with a deficiency in FK506-binding protein FKBP12.
Lin H, Hutchcroft JE, Andoniou CE, Kamoun M, Band H, Bierer BE
Association of p59(fyn) with the T lymphocyte costimulatory receptor CD2. Binding of the Fyn Src homology (SH) 3 domain is regulated by the Fyn SH2 domain. J Biol Chem. 1998 Jul 31; 273(31):19914-21.
Association of p59(fyn) with the T lymphocyte costimulatory receptor CD2. Binding of the Fyn Src homology (SH) 3 domain is regulated by the Fyn SH2 domain.
Berrueta L, Tirnauer JS, Schuyler SC, Pellman D, Bierer BE
The APC-associated protein EB1 associates with components of the dynactin complex and cytoplasmic dynein intermediate chain. Curr Biol. 1999 Apr 22; 9(8):425-8.
The APC-associated protein EB1 associates with components of the dynactin complex and cytoplasmic dynein intermediate chain.
Tirnauer JS, O'Toole E, Berrueta L, Bierer BE, Pellman D
Yeast Bim1p promotes the G1-specific dynamics of microtubules. J Cell Biol. 1999 May 31; 145(5):993-1007.
Yeast Bim1p promotes the G1-specific dynamics of microtubules.
The effect of desferrithiocin, an oral iron chelator, on T-cell function. Blood. 1990 Nov 15; 76(10):2052-9.
The effect of desferrithiocin, an oral iron chelator, on T-cell function.
Regulation of CXCR4 expression in human T lymphocytes by calcium and calcineurin. Mol Immunol. 2003 Dec; 40(8):539-53.
Regulation of CXCR4 expression in human T lymphocytes by calcium and calcineurin.
Lee SJ, Wegner SA, McGarigle CJ, Bierer BE, Antin JH
Treatment of chronic graft-versus-host disease with clofazimine. Blood. 1997 Apr 01; 89(7):2298-302.
Treatment of chronic graft-versus-host disease with clofazimine.
Bierer BE, Nishimura Y, Burakoff SJ, Smith BR
Phenotypic and functional characterization of human cytolytic T cells lacking expression of CD5. J Clin Invest. 1988 May; 81(5):1390-7.
Phenotypic and functional characterization of human cytolytic T cells lacking expression of CD5.
Bierer BE, Somers PK, Wandless TJ, Burakoff SJ, Schreiber SL
Probing immunosuppressant action with a nonnatural immunophilin ligand. Science. 1990 Oct 26; 250(4980):556-9.
Probing immunosuppressant action with a nonnatural immunophilin ligand.
The effect of the immunosuppressant FK-506 on alternate pathways of T cell activation. Eur J Immunol. 1991 Feb; 21(2):439-45.
The effect of the immunosuppressant FK-506 on alternate pathways of T cell activation.
Bierer BE, Golan DE, Brown CS, Herrmann SH, Burakoff SJ
A monoclonal antibody to LFA-3, the CD2 ligand, specifically immobilizes major histocompatibility complex proteins. Eur J Immunol. 1989 Apr; 19(4):661-5.
A monoclonal antibody to LFA-3, the CD2 ligand, specifically immobilizes major histocompatibility complex proteins.
Rosa RM, Bierer B, Thomas R, Stoff JS, Kruskall M, Robinson S, Bunn HF, Epstein FH
Transactions of the Association of American Physicians
Prevention and treatment of sickle cell crisis by induced hyponatremia. Trans Assoc Am Physicians. 1980; 93:164-74.
Prevention and treatment of sickle cell crisis by induced hyponatremia.
Antin JH, Weinstein HJ, Guinan EC, McCarthy P, Bierer BE, Gilliland DG, Parsons SK, Ballen KK, Rimm IJ, Falzarano G
Recombinant human interleukin-1 receptor antagonist in the treatment of steroid-resistant graft-versus-host disease. Blood. 1994 Aug 15; 84(4):1342-8.
Recombinant human interleukin-1 receptor antagonist in the treatment of steroid-resistant graft-versus-host disease.
Signaling through CD28/CTLA-4 family receptors: puzzling participation of phosphatidylinositol-3 kinase. J Immunol. 1996 Jun 01; 156(11):4071-4.
Signaling through CD28/CTLA-4 family receptors: puzzling participation of phosphatidylinositol-3 kinase.
Weingart SN, Price J, Duncombe D, Connor M, Sommer K, Conley KA, Bierer BE, Ponte PR
Joint Commission journal on quality and patient safety
Patient-reported safety and quality of care in outpatient oncology. Jt Comm J Qual Patient Saf. 2007 Feb; 33(2):83-94.
Patient-reported safety and quality of care in outpatient oncology.
Bierer BE, Sleckman BP, Ratnofsky SE, Burakoff SJ
The biologic roles of CD2, CD4, and CD8 in T-cell activation. Annu Rev Immunol. 1989; 7:579-99.
The biologic roles of CD2, CD4, and CD8 in T-cell activation.
Immunosuppressants FK506 and rapamycin function as reversal agents of the multidrug resistance phenotype. Blood. 1992 Sep 15; 80(6):1528-36.
Immunosuppressants FK506 and rapamycin function as reversal agents of the multidrug resistance phenotype.
Data Authorship as an Incentive to Data Sharing. N Engl J Med. 2017 07 27; 377(4):402.
Saks MJ, Albright T, Bohan TL, Bierer BE, Bowers CM, Bush MA, Bush PJ, Casadevall A, Cole SA, Denton MB, Diamond SS, Dioso-Villa R, Epstein J, Faigman D, Faigman L, Fienberg SE, Garrett BL, Giannelli PC, Greely HT, Imwinkelried E, Jamieson A, Kafadar K, Kassirer JP, Koehler J', Korn D, Mnookin J, Morrison AB, Murphy E, Peerwani N, Peterson JL, Risinger DM, Sensabaugh GF, Spiegelman C, Stern H, Thompson WC, Wayman JL, Zabell S, Zumwalt RE
Forensic bitemark identification: weak foundations, exaggerated claims. J Law Biosci. 2016 Dec; 3(3):538-575.
Forensic bitemark identification: weak foundations, exaggerated claims.
Nichols L, Brako L, Rivera SM, Tahmassian A, Jones MF, Pierce HH, Bierer BE
What do revised U.S. rules mean for human research? Science. 2017 Aug 18; 357(6352):650-651.
What do revised U.S. rules mean for human research?
Rosa RM, Bierer BE, Thomas R, Stoff JS, Kruskall M, Robinson S, Bunn HF, Epstein FH
A study of induced hyponatremia in the prevention and treatment of sickle-cell crisis. N Engl J Med. 1980 Nov 13; 303(20):1138-43.
A study of induced hyponatremia in the prevention and treatment of sickle-cell crisis.
Bierer BE, Holländer G, Fruman D, Burakoff SJ
Cyclosporin A and FK506: molecular mechanisms of immunosuppression and probes for transplantation biology. Curr Opin Immunol. 1993 Oct; 5(5):763-73.
Cyclosporin A and FK506: molecular mechanisms of immunosuppression and probes for transplantation biology.
Intracellular mediators regulate CD2 lateral diffusion and cytoplasmic Ca2+ mobilization upon CD2-mediated T cell activation. Biophys J. 1995 Feb; 68(2):459-70.
Intracellular mediators regulate CD2 lateral diffusion and cytoplasmic Ca2+ mobilization upon CD2-mediated T cell activation.
EB1 proteins regulate microtubule dynamics, cell polarity, and chromosome stability. J Cell Biol. 2000 May 15; 149(4):761-6.
EB1 proteins regulate microtubule dynamics, cell polarity, and chromosome stability.
Salazar-Fontana LI, Barr V, Samelson LE, Bierer BE
CD28 engagement promotes actin polymerization through the activation of the small Rho GTPase Cdc42 in human T cells. J Immunol. 2003 Sep 01; 171(5):2225-32.
CD28 engagement promotes actin polymerization through the activation of the small Rho GTPase Cdc42 in human T cells.
Immunophilins in protein folding and immunosuppression. FASEB J. 1994 Apr 01; 8(6):391-400.
Immunophilins in protein folding and immunosuppression.
Mechanisms of immunosuppression by FK506. Preservation of T cell transmembrane signal transduction. Transplantation. 1990 Jun; 49(6):1168-70.
Mechanisms of immunosuppression by FK506. Preservation of T cell transmembrane signal transduction.
Functional CD2 mutants unable to bind to, or be stimulated by, LFA-3. J Immunol. 1990 Feb 15; 144(4):1215-20.
Functional CD2 mutants unable to bind to, or be stimulated by, LFA-3.
Foley JE, Jung U, Miera A, Borenstein T, Mariotti J, Eckhaus M, Bierer BE, Fowler DH
Ex vivo rapamycin generates donor Th2 cells that potently inhibit graft-versus-host disease and graft-versus-tumor effects via an IL-4-dependent mechanism. J Immunol. 2005 Nov 01; 175(9):5732-43.
Ex vivo rapamycin generates donor Th2 cells that potently inhibit graft-versus-host disease and graft-versus-tumor effects via an IL-4-dependent mechanism.
T cell adhesion molecules. FASEB J. 1988 Jul; 2(10):2584-90.
Bierer BE, Emerson SG, Antin J, Maziarz R, Rappeport JM, Smith BR, Burakoff SJ
Regulation of cytotoxic T lymphocyte-mediated graft rejection following bone marrow transplantation. Transplantation. 1988 Dec; 46(6):835-9.
Regulation of cytotoxic T lymphocyte-mediated graft rejection following bone marrow transplantation.
Mentzer SJ, Bierer BE, Anderson DC, Springer TA, Burakoff SJ
Abnormal cytolytic activity of lymphocyte function-associated antigen-1-deficient human cytolytic T lymphocyte clones. J Clin Invest. 1986 Nov; 78(5):1387-91.
Abnormal cytolytic activity of lymphocyte function-associated antigen-1-deficient human cytolytic T lymphocyte clones.
Antin JH, Bierer BE, Smith BR, Ferrara J, Guinan EC, Sieff C, Golan DE, Macklis RM, Tarbell NJ, Lynch E
Selective depletion of bone marrow T lymphocytes with anti-CD5 monoclonal antibodies: effective prophylaxis for graft-versus-host disease in patients with hematologic malignancies. Blood. 1991 Oct 15; 78(8):2139-49.
Selective depletion of bone marrow T lymphocytes with anti-CD5 monoclonal antibodies: effective prophylaxis for graft-versus-host disease in patients with hematologic malignancies.
Bierer BE, Barbosa J, Herrmann S, Burakoff SJ
Interaction of CD2 with its ligand, LFA-3, in human T cell proliferation. J Immunol. 1988 May 15; 140(10):3358-63.
Interaction of CD2 with its ligand, LFA-3, in human T cell proliferation.
Cyclosporin A, FK506, and rapamycin: binding to immunophilins and biological action. Chem Immunol. 1994; 59:128-55.
Cyclosporin A, FK506, and rapamycin: binding to immunophilins and biological action.
Association of CD2 with tubulin. Evidence for a role of the cytoskeleton in T cell activation. J Biol Chem. 1993 Mar 05; 268(7):4979-88.
Association of CD2 with tubulin. Evidence for a role of the cytoskeleton in T cell activation.
Nishimura Y, Bierer BE, Jones WK, Jones NH, Strominger JL, Burakoff SJ
Expression and function of a CD5 cDNA in human and murine T cells. Eur J Immunol. 1988 May; 18(5):747-53.
Expression and function of a CD5 cDNA in human and murine T cells.
Ohmann C, Banzi R, Canham S, Battaglia S, Matei M, Ariyo C, Becnel L, Bierer B, Bowers S, Clivio L, Dias M, Druml C, Faure H, Fenner M, Galvez J, Ghersi D, Gluud C, Groves T, Houston P, Karam G, Kalra D, Knowles RL, Krleža-Jeric K, Kubiak C, Kuchinke W, Kush R, Lukkarinen A, Marques PS, Newbigging A, O'Callaghan J, Ravaud P, Schlünder I, Shanahan D, Sitter H, Spalding D, Tudur-Smith C, van Reusel P, van Veen EB, Visser GR, Wilson J, Demotes-Mainard J
Sharing and reuse of individual participant data from clinical trials: principles and recommendations. BMJ Open. 2017 Dec 14; 7(12):e018647.
Sharing and reuse of individual participant data from clinical trials: principles and recommendations.
Bierer BE, Herrmann SH, Brown CS, Burakoff SJ, Golan DE
Lateral mobility of class I histocompatibility antigens in B lymphoblastoid cell membranes: modulation by cross-linking and effect of cell density. J Cell Biol. 1987 Sep; 105(3):1147-52.
Lateral mobility of class I histocompatibility antigens in B lymphoblastoid cell membranes: modulation by cross-linking and effect of cell density.
Activation-dependent phosphorylation of the T-lymphocyte surface receptor CD28 and associated proteins. Proc Natl Acad Sci U S A. 1994 Apr 12; 91(8):3260-4.
Activation-dependent phosphorylation of the T-lymphocyte surface receptor CD28 and associated proteins.
Differential phosphorylation of the T lymphocyte costimulatory receptor CD28. Activation-dependent changes and regulation by protein kinase C. J Biol Chem. 1996 Jun 07; 271(23):13362-70.
Differential phosphorylation of the T lymphocyte costimulatory receptor CD28. Activation-dependent changes and regulation by protein kinase C.
Hendrickson BA, Zhang W, Craig RJ, Jin YJ, Bierer BE, Burakoff S, DiLella AG
Structural organization of the genes encoding human and murine FK506-binding protein (FKBP) 13 and comparison to FKBP1. Gene. 1993 Dec 08; 134(2):271-5.
Structural organization of the genes encoding human and murine FK506-binding protein (FKBP) 13 and comparison to FKBP1.
Calvo V, Wood M, Gjertson C, Vik T, Bierer BE
Activation of 70-kDa S6 kinase, induced by the cytokines interleukin-3 and erythropoietin and inhibited by rapamycin, is not an absolute requirement for cell proliferation. Eur J Immunol. 1994 Nov; 24(11):2664-71.
Activation of 70-kDa S6 kinase, induced by the cytokines interleukin-3 and erythropoietin and inhibited by rapamycin, is not an absolute requirement for cell proliferation.
Venipuncture Procedures: Sources of Human Peripheral Blood Cells, Serum, and Plasma. Curr Protoc Immunol. 2017 Aug 01; 118:A.3F.1-A.3F.5.
Venipuncture Procedures: Sources of Human Peripheral Blood Cells, Serum, and Plasma.
Universal Precautions: Necessary Safety Procedures When Handling Human Blood, Body Fluids, and Specimens. Curr Protoc Immunol. 2017 Aug 01; 118:A.3P.1-A.3P.3.
Universal Precautions: Necessary Safety Procedures When Handling Human Blood, Body Fluids, and Specimens.
Bringhurst FR, Bierer BE, Godeau F, Neyhard N, Varner V, Segre GV
Humoral hypercalcemia of malignancy. Release of a prostaglandin-stimulating bone-resorbing factor in vitro by human transitional-cell carcinoma cells. J Clin Invest. 1986 Feb; 77(2):456-64.
Humoral hypercalcemia of malignancy. Release of a prostaglandin-stimulating bone-resorbing factor in vitro by human transitional-cell carcinoma cells.
Berrueta L, Kraeft SK, Tirnauer JS, Schuyler SC, Chen LB, Hill DE, Pellman D, Bierer BE
The adenomatous polyposis coli-binding protein EB1 is associated with cytoplasmic and spindle microtubules. Proc Natl Acad Sci U S A. 1998 Sep 01; 95(18):10596-601.
The adenomatous polyposis coli-binding protein EB1 is associated with cytoplasmic and spindle microtubules.
Price DJ, Grove JR, Calvo V, Avruch J, Bierer BE
Rapamycin-induced inhibition of the 70-kilodalton S6 protein kinase. Science. 1992 Aug 14; 257(5072):973-7.
Rapamycin-induced inhibition of the 70-kilodalton S6 protein kinase.
T cell receptor activation of a ribosomal S6 kinase activity. Eur J Immunol. 1992 Feb; 22(2):457-62.
T cell receptor activation of a ribosomal S6 kinase activity.
Rosenstein Y, Park JK, Hahn WC, Rosen FS, Bierer BE, Burakoff SJ
CD43, a molecule defective in Wiskott-Aldrich syndrome, binds ICAM-1. Nature. 1991 Nov 21; 354(6350):233-5.
CD43, a molecule defective in Wiskott-Aldrich syndrome, binds ICAM-1.
Holländer GA, Fruman DA, Bierer BE, Burakoff SJ
Disruption of T cell development and repertoire selection by calcineurin inhibition in vivo. Transplantation. 1994 Nov 15; 58(9):1037-43.
Disruption of T cell development and repertoire selection by calcineurin inhibition in vivo.
Fruman DA, Wood MA, Gjertson CK, Katz HR, Burakoff SJ, Bierer BE
FK506 binding protein 12 mediates sensitivity to both FK506 and rapamycin in murine mast cells. Eur J Immunol. 1995 Feb; 25(2):563-71.
FK506 binding protein 12 mediates sensitivity to both FK506 and rapamycin in murine mast cells.
Hahn WC, Menu E, Bothwell AL, Sims PJ, Bierer BE
Overlapping but nonidentical binding sites on CD2 for CD58 and a second ligand CD59. Science. 1992 Jun 26; 256(5065):1805-7.
Overlapping but nonidentical binding sites on CD2 for CD58 and a second ligand CD59.