Bierer, Barbara
completed student projects: Determining the Optimal Pathway for Clinical Trial Management at Montefiore/Einstein
eCommons Login: BEB2
first name: Barbara
last name: Bierer
coauthor of: Witte, Elizabeth
coauthor of: Ligibel, Jennifer
coauthor of: Hahn, William
coauthor of: Ne'eman, Ari
coauthor of: Lu, Weidong
full name: Barbara Emily Bierer, M.D.
has faculty rank: Full Professor
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Person ID: 82143
person in primary position: Professor of Medicine (Pediatrics)
physical neighbor: Gupta, Neil
physical neighbor: Palazuelos, Daniel
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similar to: Drazen, Jeffrey
similar to: Rubin, Eric
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similar to: Bourgeois, Florence
similar to: Iezzoni, Lisa
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selected publications: Authorship 1795584
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Molecular and biological actions of cyclosporin A and FK506 on T cell development and function.
PubMed Identifier: 10155542
author list: Holländer GA, Bierer BE, Burakoff SJ
published in: Transfusion science
information resource reference: Molecular and biological actions of cyclosporin A and FK506 on T cell development and function. Transfus Sci. 1994 Sep; 15(3):207-20.
journal title abbreviation: Transfus Sci
publication date: 1994-09-01T00:00:00
year: 1994
type: Academic Article
type: Article
type: Document
type: Information Resource

The actin cytoskeleton, membrane lipid microdomains, and T cell signal transduction.
PubMed Identifier: 11293114
author list: Morley SC, Bierer BE
published in: Advances in immunology
information resource reference: The actin cytoskeleton, membrane lipid microdomains, and T cell signal transduction. Adv Immunol. 2001; 77:1-43.
journal title abbreviation: Adv Immunol
publication date: 2001-01-01T00:00:00
year: 2001
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1047099
type: Authorship
author rank in publication: 5
linked author: Bierer, Barbara
linked information resource: A Framework for Ethical Payment to Research Participants.

A Framework for Ethical Payment to Research Participants.
PubMed Identifier: 29466147
author list: Gelinas L, Largent EA, Cohen IG, Kornetsky S, Bierer BE, Fernandez Lynch H
published in: The New England journal of medicine
information resource reference: A Framework for Ethical Payment to Research Participants. N Engl J Med. 2018 02 22; 378(8):766-771.
journal title abbreviation: N Engl J Med
publication date: 2018-02-22T00:00:00
year: 2018
type: Academic Article
type: Article
type: Document
type: Information Resource

Partial deletions of the cytoplasmic domain of CD2 result in a partial defect in signal transduction.
PubMed Identifier: 1967272
author list: Bierer BE, Bogart RE, Burakoff SJ
published in: Journal of immunology (Baltimore, Md. : 1950)
information resource reference: Partial deletions of the cytoplasmic domain of CD2 result in a partial defect in signal transduction. J Immunol. 1990 Feb 01; 144(3):785-9.
journal title abbreviation: J Immunol
publication date: 1990-02-01T00:00:00
year: 1990
type: Academic Article
type: Article
type: Document
type: Information Resource

Expression of CD5 regulates responsiveness to IL-1.
PubMed Identifier: 2460534
author list: Nishimura Y, Bierer BE, Burakoff SJ
published in: Journal of immunology (Baltimore, Md. : 1950)
information resource reference: Expression of CD5 regulates responsiveness to IL-1. J Immunol. 1988 Nov 15; 141(10):3438-44.
journal title abbreviation: J Immunol
publication date: 1988-11-15T00:00:00
year: 1988
type: Academic Article
type: Article
type: Document
type: Information Resource

Characterization of a mutant calcineurin A alpha gene expressed by EL4 lymphoma cells.
PubMed Identifier: 7791792
author list: Fruman DA, Pai SY, Burakoff SJ, Bierer BE
published in: Molecular and cellular biology
information resource reference: Characterization of a mutant calcineurin A alpha gene expressed by EL4 lymphoma cells. Mol Cell Biol. 1995 Jul; 15(7):3857-63.
journal title abbreviation: Mol Cell Biol
publication date: 1995-07-01T00:00:00
year: 1995
type: Academic Article
type: Article
type: Document
type: Information Resource

Mechanisms of action of immunosuppressive agents: cyclosporin A, FK506, and rapamycin.
PubMed Identifier: 8630742
author list: Bierer BE
published in: Proceedings of the Association of American Physicians
information resource reference: Mechanisms of action of immunosuppressive agents: cyclosporin A, FK506, and rapamycin. Proc Assoc Am Physicians. 1995 Apr; 107(1):28-40.
journal title abbreviation: Proc Assoc Am Physicians
publication date: 1995-04-01T00:00:00
year: 1995
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1056159
type: Authorship
author rank in publication: 3
linked author: Bierer, Barbara
linked information resource: On Scarcity and the Value of Clinical Trials.

On Scarcity and the Value of Clinical Trials.
PubMed Identifier: 29621470
author list: Gelinas L, Lynch HF, Bierer BE, Cohen IG
published in: The American journal of bioethics : AJOB
information resource reference: On Scarcity and the Value of Clinical Trials. Am J Bioeth. 2018 04; 18(4):71-73.
journal title abbreviation: Am J Bioeth
publication date: 2018-04-01T00:00:00
year: 2018
type: Academic Article
type: Article
type: Document
type: Information Resource

Two distinct signal transmission pathways in T lymphocytes are inhibited by complexes formed between an immunophilin and either FK506 or rapamycin.
PubMed Identifier: 2123553
author list: Bierer BE, Mattila PS, Standaert RF, Herzenberg LA, Burakoff SJ, Crabtree G, Schreiber SL
published in: Proceedings of the National Academy of Sciences of the United States of America
information resource reference: Two distinct signal transmission pathways in T lymphocytes are inhibited by complexes formed between an immunophilin and either FK506 or rapamycin. Proc Natl Acad Sci U S A. 1990 Dec; 87(23):9231-5.
journal title abbreviation: Proc Natl Acad Sci U S A
publication date: 1990-12-01T00:00:00
year: 1990
type: Academic Article
type: Article
type: Document
type: Information Resource

Identification of novel targets of immunosuppressive agents by cDNA-based microarray analysis.
PubMed Identifier: 11694517
author list: Cristillo AD, Bierer BE
published in: The Journal of biological chemistry
information resource reference: Identification of novel targets of immunosuppressive agents by cDNA-based microarray analysis. J Biol Chem. 2002 Feb 08; 277(6):4465-76.
journal title abbreviation: J Biol Chem
publication date: 2001-11-01T00:00:00
year: 2001
type: Academic Article
type: Article
type: Document
type: Information Resource

Inhibition of actin polymerization enhances commitment to and execution of apoptosis induced by withdrawal of trophic support.
PubMed Identifier: 12616543
author list: Celeste Morley S, Sun GP, Bierer BE
published in: Journal of cellular biochemistry
information resource reference: Inhibition of actin polymerization enhances commitment to and execution of apoptosis induced by withdrawal of trophic support. J Cell Biochem. 2003 Apr 01; 88(5):1066-76.
journal title abbreviation: J Cell Biochem
publication date: 2003-04-01T00:00:00
year: 2003
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1061605
type: Authorship
author rank in publication: 1
linked author: Bierer, Barbara
linked information resource: Revised 'Common Rule' Shapes Protections For Research Participants.

Revised 'Common Rule' Shapes Protections For Research Participants.
PubMed Identifier: 28461343
author list: Bierer BE, Barnes M, Lynch HF
published in: Health affairs (Project Hope)
information resource reference: Revised 'Common Rule' Shapes Protections For Research Participants. Health Aff (Millwood). 2017 05 01; 36(5):784-788.
journal title abbreviation: Health Aff (Millwood)
publication date: 2017-05-01T00:00:00
year: 2017
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1063240
type: Authorship
author rank in publication: 6
linked author: Bierer, Barbara
linked information resource: Truth in Advertising: Disclosure of Participant Payment in Research Recruitment Materials.

Truth in Advertising: Disclosure of Participant Payment in Research Recruitment Materials.
PubMed Identifier: 29714586
author list: Gelinas L, Lynch HF, Largent EA, Shachar C, Cohen IG, Bierer BE
published in: Therapeutic innovation & regulatory science
information resource reference: Truth in Advertising: Disclosure of Participant Payment in Research Recruitment Materials. Ther Innov Regul Sci. 2018 05; 52(3):268-274.
journal title abbreviation: Ther Innov Regul Sci
publication date: 2018-04-08T00:00:00
year: 2018
type: Academic Article
type: Article
type: Document
type: Information Resource

Rapamycin inhibits clonal expansion and adipogenic differentiation of 3T3-L1 cells.
PubMed Identifier: 7479942
author list: Yeh WC, Bierer BE, McKnight SL
published in: Proceedings of the National Academy of Sciences of the United States of America
information resource reference: Rapamycin inhibits clonal expansion and adipogenic differentiation of 3T3-L1 cells. Proc Natl Acad Sci U S A. 1995 Nov 21; 92(24):11086-90.
journal title abbreviation: Proc Natl Acad Sci U S A
publication date: 1995-11-21T00:00:00
year: 1995
type: Academic Article
type: Article
type: Document
type: Information Resource

The complex of FK506-binding protein 12 and FK506 inhibits calcineurin phosphatase activity and IgE activation-induced cytokine transcripts, but not exocytosis, in mouse mast cells.
PubMed Identifier: 7530743
author list: Fruman DA, Bierer BE, Benes JE, Burakoff SJ, Austen KF, Katz HR
published in: Journal of immunology (Baltimore, Md. : 1950)
information resource reference: The complex of FK506-binding protein 12 and FK506 inhibits calcineurin phosphatase activity and IgE activation-induced cytokine transcripts, but not exocytosis, in mouse mast cells. J Immunol. 1995 Feb 15; 154(4):1846-51.
journal title abbreviation: J Immunol
publication date: 1995-02-15T00:00:00
year: 1995
type: Academic Article
type: Article
type: Document
type: Information Resource

Differential chemokine expression profiles in human peripheral blood T lymphocytes: dependence on T-cell coreceptor and calcineurin signaling.
PubMed Identifier: 12393716
author list: Cristillo AD, Macri MJ, Bierer BE
published in: Blood
information resource reference: Differential chemokine expression profiles in human peripheral blood T lymphocytes: dependence on T-cell coreceptor and calcineurin signaling. Blood. 2003 Jan 01; 101(1):216-25.
journal title abbreviation: Blood
publication date: 2002-08-15T00:00:00
year: 2002
type: Academic Article
type: Article
type: Document
type: Information Resource

Analysis of CD4 and CD2 receptor function.
PubMed Identifier: 2908352
author list: Goldman SJ, Bierer BE, Burakoff SJ
published in: Princess Takamatsu symposia
information resource reference: Analysis of CD4 and CD2 receptor function. Princess Takamatsu Symp. 1988; 19:149-60.
journal title abbreviation: Princess Takamatsu Symp
publication date: 1988-01-01T00:00:00
year: 1988
type: Academic Article
type: Article
type: Document
type: Information Resource

Expression of human interleukin-3 (multi-CSF) is restricted to human lymphocytes and T-cell tumor lines.
PubMed Identifier: 2645952
author list: Niemeyer CM, Sieff CA, Mathey-Prevot B, Wimperis JZ, Bierer BE, Clark SC, Nathan DG
published in: Blood
information resource reference: Expression of human interleukin-3 (multi-CSF) is restricted to human lymphocytes and T-cell tumor lines. Blood. 1989 Mar; 73(4):945-51.
journal title abbreviation: Blood
publication date: 1989-03-01T00:00:00
year: 1989
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1074048
type: Authorship
author rank in publication: 1
linked author: Bierer, Barbara
linked information resource: Isolation and Differentiation of Stem and Progenitor Cells.

Isolation and Differentiation of Stem and Progenitor Cells.
PubMed Identifier: 29921114
author list: Bierer BE
published in: Current protocols in immunology
information resource reference: Isolation and Differentiation of Stem and Progenitor Cells. Curr Protoc Immunol. 2005 Apr; 66(1):1.
journal title abbreviation: Curr Protoc Immunol
publication date: 2005-04-01T00:00:00
year: 2005
type: Academic Article
type: Article
type: Document
type: Information Resource

The treatment of sickle cell anemia with induced hyponatremia.
PubMed Identifier: 7159756
author list: Rosa RM, Bierer BE, Bunn HF, Epstein FH
published in: Blood cells
information resource reference: The treatment of sickle cell anemia with induced hyponatremia. Blood Cells. 1982; 8(2):329-35.
journal title abbreviation: Blood Cells
publication date: 1982-01-01T00:00:00
year: 1982
type: Academic Article
type: Article
type: Document
type: Information Resource

Identification of a physical interaction between calcineurin and nuclear factor of activated T cells (NFATp).
PubMed Identifier: 8576111
author list: Wesselborg S, Fruman DA, Sagoo JK, Bierer BE, Burakoff SJ
published in: The Journal of biological chemistry
information resource reference: Identification of a physical interaction between calcineurin and nuclear factor of activated T cells (NFATp). J Biol Chem. 1996 Jan 19; 271(3):1274-7.
journal title abbreviation: J Biol Chem
publication date: 1996-01-19T00:00:00
year: 1996
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1077701
type: Authorship
author rank in publication: 2
linked author: Bierer, Barbara
linked information resource: Assessment of a shortened informed consent form for pediatric research: a pilot study.

Assessment of a shortened informed consent form for pediatric research: a pilot study.
PubMed Identifier: 29967521
author list: Murray PD, Bierer BE, Hirschfeld S, Klein AK, Davis JM
published in: Pediatric research
information resource reference: Assessment of a shortened informed consent form for pediatric research: a pilot study. Pediatr Res. 2018 10; 84(4):516-519.
journal title abbreviation: Pediatr Res
publication date: 2018-05-18T00:00:00
year: 2018
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 117085
type: Authorship
author rank in publication: 2
linked author: Bierer, Barbara
linked information resource: Cell-mediated immunity.

Authorship 1082559
type: Authorship
author rank in publication: 10
linked author: Bierer, Barbara
linked information resource: Reimagining Health Data Exchange: An Application Programming Interface-Enabled Roadmap for India.

Reimagining Health Data Exchange: An Application Programming Interface-Enabled Roadmap for India.
PubMed Identifier: 30006325
author list: Balsari S, Fortenko A, Blaya JA, Gropper A, Jayaram M, Matthan R, Sahasranam R, Shankar M, Sarbadhikari SN, Bierer BE, Mandl KD, Mehendale S, Khanna T
published in: Journal of medical Internet research
information resource reference: Reimagining Health Data Exchange: An Application Programming Interface-Enabled Roadmap for India. J Med Internet Res. 2018 07 13; 20(7):e10725.
journal title abbreviation: J Med Internet Res
publication date: 2018-07-13T00:00:00
year: 2018
type: Academic Article
type: Article
type: Document
type: Information Resource

The role of functional cell surface antigens in T cell activation.
PubMed Identifier: 2953146
author list: Bierer BE, Mentzer SJ, Greenstein JL, Burakoff SJ
published in: The Year in immunology
information resource reference: The role of functional cell surface antigens in T cell activation. Year Immunol. 1986; 2:39-59.
journal title abbreviation: Year Immunol
publication date: 1986-01-01T00:00:00
year: 1986
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 119766
type: Authorship
author rank in publication: 5
linked author: Bierer, Barbara
linked information resource: https://connects.catalyst.harvard.edu/Profiles/profile/783405

Separable portions of the CD2 cytoplasmic domain involved in signaling and ligand avidity regulation.
PubMed Identifier: 7901319
author list: Hahn WC, Bierer BE
published in: The Journal of experimental medicine
information resource reference: Separable portions of the CD2 cytoplasmic domain involved in signaling and ligand avidity regulation. J Exp Med. 1993 Nov 01; 178(5):1831-6.
journal title abbreviation: J Exp Med
publication date: 1993-11-01T00:00:00
year: 1993
type: Academic Article
type: Article
type: Document
type: Information Resource

Localization of the FK506-binding protein, FKBP 13, to the lumen of the endoplasmic reticulum.
PubMed Identifier: 8373365
author list: Nigam SK, Jin YJ, Jin MJ, Bush KT, Bierer BE, Burakoff SJ
published in: The Biochemical journal
information resource reference: Localization of the FK506-binding protein, FKBP 13, to the lumen of the endoplasmic reticulum. Biochem J. 1993 Sep 01; 294 ( Pt 2):511-5.
journal title abbreviation: Biochem J
publication date: 1993-09-01T00:00:00
year: 1993
type: Academic Article
type: Article
type: Document
type: Information Resource

A large proportion of T lymphocytes lack CD5 expression after bone marrow transplantation.
PubMed Identifier: 2467708
author list: Bierer BE, Burakoff SJ, Smith BR
published in: Blood
information resource reference: A large proportion of T lymphocytes lack CD5 expression after bone marrow transplantation. Blood. 1989 Apr; 73(5):1359-66.
journal title abbreviation: Blood
publication date: 1989-04-01T00:00:00
year: 1989
type: Academic Article
type: Article
type: Document
type: Information Resource

Q-T prolongation and torsades de pointes ventricular tachycardia produced by the tetracyclic antidepressant agent maprotiline.
PubMed Identifier: 6829452
author list: Herrmann HC, Kaplan LM, Bierer BE
published in: The American journal of cardiology
information resource reference: Q-T prolongation and torsades de pointes ventricular tachycardia produced by the tetracyclic antidepressant agent maprotiline. Am J Cardiol. 1983 Mar 01; 51(5):904-6.
journal title abbreviation: Am J Cardiol
publication date: 1983-03-01T00:00:00
year: 1983
type: Academic Article
type: Article
type: Document
type: Information Resource

Expression of the T-cell surface molecule CD2 and an epitope-loss CD2 mutant to define the role of lymphocyte function-associated antigen 3 (LFA-3) in T-cell activation.
PubMed Identifier: 2448792
author list: Bierer BE, Peterson A, Barbosa J, Seed B, Burakoff SJ
published in: Proceedings of the National Academy of Sciences of the United States of America
information resource reference: Expression of the T-cell surface molecule CD2 and an epitope-loss CD2 mutant to define the role of lymphocyte function-associated antigen 3 (LFA-3) in T-cell activation. Proc Natl Acad Sci U S A. 1988 Feb; 85(4):1194-8.
journal title abbreviation: Proc Natl Acad Sci U S A
publication date: 1988-02-01T00:00:00
year: 1988
type: Academic Article
type: Article
type: Document
type: Information Resource

T-lymphocyte activation: the biology and function of CD2 and CD4.
PubMed Identifier: 2483402
author list: Bierer BE, Burakoff SJ
published in: Immunological reviews
information resource reference: T-lymphocyte activation: the biology and function of CD2 and CD4. Immunol Rev. 1989 Oct; 111:267-94.
journal title abbreviation: Immunol Rev
publication date: 1989-10-01T00:00:00
year: 1989
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1090434
type: Authorship
author rank in publication: 3
linked author: Bierer, Barbara
linked information resource: Public Engagement, Notice-and-Comment Rulemaking, and the Common Rule.

Public Engagement, Notice-and-Comment Rulemaking, and the Common Rule.
PubMed Identifier: 30148327
author list: Lynch HF, Cohen IG, Bierer BE
published in: IRB
information resource reference: Public Engagement, Notice-and-Comment Rulemaking, and the Common Rule. IRB. 2017 Jan-Feb; 39(1):17-9.
journal title abbreviation: IRB
publication date: 2017-01-01T00:00:00
year: 2017
type: Academic Article
type: Article
type: Document
type: Information Resource

Functional analysis of CD2, CD4, and CD8 in T-cell activation.
PubMed Identifier: 3052208
author list: Bierer BE, Greenstein JL, Sleckman B, Ratnofsky S, Peterson A, Seed B, Burakoff SJ
published in: Annals of the New York Academy of Sciences
information resource reference: Functional analysis of CD2, CD4, and CD8 in T-cell activation. Ann N Y Acad Sci. 1988; 532:199-206.
journal title abbreviation: Ann N Y Acad Sci
publication date: 1988-01-01T00:00:00
year: 1988
type: Academic Article
type: Article
type: Document
type: Information Resource

Sialophorin, a surface sialoglycoprotein defective in the Wiskott-Aldrich syndrome, is involved in human T lymphocyte proliferation.
PubMed Identifier: 3572301
author list: Mentzer SJ, Remold-O'Donnell E, Crimmins MA, Bierer BE, Rosen FS, Burakoff SJ
published in: The Journal of experimental medicine
information resource reference: Sialophorin, a surface sialoglycoprotein defective in the Wiskott-Aldrich syndrome, is involved in human T lymphocyte proliferation. J Exp Med. 1987 May 01; 165(5):1383-92.
journal title abbreviation: J Exp Med
publication date: 1987-05-01T00:00:00
year: 1987
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1092517
type: Authorship
author rank in publication: 1
linked author: Bierer, Barbara
linked information resource: Responsibilities of Data Monitoring Committees: Consensus Recommendations.

Responsibilities of Data Monitoring Committees: Consensus Recommendations.
PubMed Identifier: 30231760
author list: Bierer BE, Li R, Seltzer J, Sleeper LA, Frank E, Knirsch C, Aldinger CE, Levine RJ, Massaro J, Shah A, Barnes M, Snapinn S, Wittes J
published in: Therapeutic innovation & regulatory science
information resource reference: Responsibilities of Data Monitoring Committees: Consensus Recommendations. Ther Innov Regul Sci. 2016 Sep; 50(5):648-659.
journal title abbreviation: Ther Innov Regul Sci
publication date: 2016-07-10T00:00:00
year: 2016
type: Academic Article
type: Article
type: Document
type: Information Resource

Cell-mediated immunity.
PubMed Identifier: 8424973
author list: Goust JM, Bierer B
published in: Immunology series
information resource reference: Cell-mediated immunity. Immunol Ser. 1993; 58:187-212.
journal title abbreviation: Immunol Ser
publication date: 1993-01-01T00:00:00
year: 1993
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1106970
type: Authorship
author rank in publication: 6
linked author: Bierer, Barbara
linked information resource: Leveling the Joint Task Force Core Competencies for Clinical Research Professionals.

Leveling the Joint Task Force Core Competencies for Clinical Research Professionals.
PubMed Identifier: 30336683
author list: Sonstein SA, Namenek Brower RJ, Gluck W, Kolb HR, Aldinger C, Bierer BE, Jones CT
published in: Therapeutic innovation & regulatory science
information resource reference: Leveling the Joint Task Force Core Competencies for Clinical Research Professionals. Ther Innov Regul Sci. 2018 Oct 18; 2168479018799291.
journal title abbreviation: Ther Innov Regul Sci
publication date: 2018-10-18T00:00:00
year: 2018
type: Academic Article
type: Article
type: Document
type: Information Resource

Calcineurin phosphatase activity in T lymphocytes is inhibited by FK 506 and cyclosporin A.
PubMed Identifier: 1373887
author list: Fruman DA, Klee CB, Bierer BE, Burakoff SJ
published in: Proceedings of the National Academy of Sciences of the United States of America
information resource reference: Calcineurin phosphatase activity in T lymphocytes is inhibited by FK 506 and cyclosporin A. Proc Natl Acad Sci U S A. 1992 May 01; 89(9):3686-90.
journal title abbreviation: Proc Natl Acad Sci U S A
publication date: 1992-05-01T00:00:00
year: 1992
type: Academic Article
type: Article
type: Document
type: Information Resource

Biology of cyclosporin A and FK506.
PubMed Identifier: 7536944
author list: Bierer BE
published in: Progress in clinical and biological research
information resource reference: Biology of cyclosporin A and FK506. Prog Clin Biol Res. 1994; 390:203-23.
journal title abbreviation: Prog Clin Biol Res
publication date: 1994-01-01T00:00:00
year: 1994
type: Academic Article
type: Article
type: Document
type: Information Resource

CD4, CD8 and CD2 in T cell adhesion and signaling.
PubMed Identifier: 7906216
author list: Collins TL, Hahn WC, Bierer BE, Burakoff SJ
published in: Current topics in microbiology and immunology
information resource reference: CD4, CD8 and CD2 in T cell adhesion and signaling. Curr Top Microbiol Immunol. 1993; 184:223-33.
journal title abbreviation: Curr Top Microbiol Immunol
publication date: 1993-01-01T00:00:00
year: 1993
type: Academic Article
type: Article
type: Document
type: Information Resource

FK506 (Tacrolimus) monotherapy for prevention of graft-versus-host disease after histocompatible sibling allogenic bone marrow transplantation.
PubMed Identifier: 8605372
author list: Fay JW, Wingard JR, Antin JH, Collins RH, Piñeiro LA, Blazar BR, Saral R, Bierer BE, Przepiorka D, Fitzsimmons WE, Maher RM, Weisdorf DJ
published in: Blood
information resource reference: FK506 (Tacrolimus) monotherapy for prevention of graft-versus-host disease after histocompatible sibling allogenic bone marrow transplantation. Blood. 1996 Apr 15; 87(8):3514-9.
journal title abbreviation: Blood
publication date: 1996-04-15T00:00:00
year: 1996
type: Academic Article
type: Article
type: Document
type: Information Resource

Synergistic T cell activation via the physiological ligands for CD2 and the T cell receptor.
PubMed Identifier: 2459290
author list: Bierer BE, Peterson A, Gorga JC, Herrmann SH, Burakoff SJ
published in: The Journal of experimental medicine
information resource reference: Synergistic T cell activation via the physiological ligands for CD2 and the T cell receptor. J Exp Med. 1988 Sep 01; 168(3):1145-56.
journal title abbreviation: J Exp Med
publication date: 1988-09-01T00:00:00
year: 1988
type: Academic Article
type: Article
type: Document
type: Information Resource

Identification and characterization of an immunophilin expressed during the clonal expansion phase of adipocyte differentiation.
PubMed Identifier: 7479941
author list: Yeh WC, Li TK, Bierer BE, McKnight SL
published in: Proceedings of the National Academy of Sciences of the United States of America
information resource reference: Identification and characterization of an immunophilin expressed during the clonal expansion phase of adipocyte differentiation. Proc Natl Acad Sci U S A. 1995 Nov 21; 92(24):11081-5.
journal title abbreviation: Proc Natl Acad Sci U S A
publication date: 1995-11-21T00:00:00
year: 1995
type: Academic Article
type: Article
type: Document
type: Information Resource

https://connects.catalyst.harvard.edu/Profiles/profile/1130805
PubMed Identifier: 9794375
author list: Hutchcroft JE, Slavik JM, Lin H, Watanabe T, Bierer BE
published in: Journal of immunology (Baltimore, Md. : 1950)
information resource reference: Uncoupling activation-dependent HS1 phosphorylation from nuclear factor of activated T cells transcriptional activation in Jurkat T cells: differential signaling through CD3 and the costimulatory receptors CD2 and CD28. J Immunol. 1998 Nov 01; 161(9):4506-12.
journal title abbreviation: J Immunol
publication date: 1998-11-01T00:00:00
year: 1998
type: Academic Article
type: Article
type: Document
type: Information Resource
label: Uncoupling activation-dependent HS1 phosphorylation from nuclear factor of activated T cells transcriptional activation in Jurkat T cells: differential signaling through CD3 and the costimulatory receptors CD2 and CD28.

CD80 and CD86 are not equivalent in their ability to induce the tyrosine phosphorylation of CD28.
PubMed Identifier: 9915850
author list: Slavik JM, Hutchcroft JE, Bierer BE
published in: The Journal of biological chemistry
information resource reference: CD80 and CD86 are not equivalent in their ability to induce the tyrosine phosphorylation of CD28. J Biol Chem. 1999 Jan 29; 274(5):3116-24.
journal title abbreviation: J Biol Chem
publication date: 1999-01-29T00:00:00
year: 1999
type: Academic Article
type: Article
type: Document
type: Information Resource

CD59 costimulation of T cell activation. CD58 dependence and requirement for glycosylation.
PubMed Identifier: 7521361
author list: Menu E, Tsai BC, Bothwell AL, Sims PJ, Bierer BE
published in: Journal of immunology (Baltimore, Md. : 1950)
information resource reference: CD59 costimulation of T cell activation. CD58 dependence and requirement for glycosylation. J Immunol. 1994 Sep 15; 153(6):2444-56.
journal title abbreviation: J Immunol
publication date: 1994-09-15T00:00:00
year: 1994
type: Academic Article
type: Article
type: Document
type: Information Resource

Cross-linking CD28 leads to activation of 70-kDa S6 kinase.
PubMed Identifier: 7523138
author list: Pai SY, Calvo V, Wood M, Bierer BE
published in: European journal of immunology
information resource reference: Cross-linking CD28 leads to activation of 70-kDa S6 kinase. Eur J Immunol. 1994 Oct; 24(10):2364-8.
journal title abbreviation: Eur J Immunol
publication date: 1994-10-01T00:00:00
year: 1994
type: Academic Article
type: Article
type: Document
type: Information Resource

T cell adhesion, avidity regulation and signaling: a molecular analysis of CD2.
PubMed Identifier: 7693022
author list: Bierer BE, Hahn WC
published in: Seminars in immunology
information resource reference: T cell adhesion, avidity regulation and signaling: a molecular analysis of CD2. Semin Immunol. 1993 Aug; 5(4):249-61.
journal title abbreviation: Semin Immunol
publication date: 1993-08-01T00:00:00
year: 1993
type: Academic Article
type: Article
type: Document
type: Information Resource

Inhibition of calcineurin phosphatase activity in adult bone marrow transplant patients treated with cyclosporine A.
PubMed Identifier: 7949153
author list: Pai SY, Fruman DA, Leong T, Neuberg D, Rosano TG, McGarigle C, Antin JH, Bierer BE
published in: Blood
information resource reference: Inhibition of calcineurin phosphatase activity in adult bone marrow transplant patients treated with cyclosporine A. Blood. 1994 Dec 01; 84(11):3974-9.
journal title abbreviation: Blood
publication date: 1994-12-01T00:00:00
year: 1994
type: Academic Article
type: Article
type: Document
type: Information Resource

Prognostic factors for treatment outcome in autotransplantation of intermediate-grade and high-grade non-Hodgkin's lymphoma with cyclophosphamide, carmustine, and etoposide.
PubMed Identifier: 8099120
author list: Wheeler C, Strawderman M, Ayash L, Churchill WH, Bierer BE, Elias A, Gilliland DG, Antman K, Guinan EC, Eder JP
published in: Journal of clinical oncology : official journal of the American Society of Clinical Oncology
information resource reference: Prognostic factors for treatment outcome in autotransplantation of intermediate-grade and high-grade non-Hodgkin's lymphoma with cyclophosphamide, carmustine, and etoposide. J Clin Oncol. 1993 Jun; 11(6):1085-91.
journal title abbreviation: J Clin Oncol
publication date: 1993-06-01T00:00:00
year: 1993
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1116089
type: Authorship
author rank in publication: 1
linked author: Bierer, Barbara
linked information resource: Universal Funder Responsibilities That Advance Social Value.

Universal Funder Responsibilities That Advance Social Value.
PubMed Identifier: 30475185
author list: Bierer BE, Strauss DH, White SA, Zarin DA
published in: The American journal of bioethics : AJOB
information resource reference: Universal Funder Responsibilities That Advance Social Value. Am J Bioeth. 2018 Nov; 18(11):30-32.
journal title abbreviation: Am J Bioeth
publication date: 2018-11-01T00:00:00
year: 2018
type: Academic Article
type: Article
type: Document
type: Information Resource

The complete sequences of plasmids pFNeo and pMH-Neo: convenient expression vectors for high-level expression of eukaryotic genes in hematopoietic cell lines.
PubMed Identifier: 8500769
author list: Hahn WC, Menzin E, Saito T, Germain RN, Bierer BE
published in: Gene
information resource reference: The complete sequences of plasmids pFNeo and pMH-Neo: convenient expression vectors for high-level expression of eukaryotic genes in hematopoietic cell lines. Gene. 1993 May 30; 127(2):267-8.
journal title abbreviation: Gene
publication date: 1993-05-30T00:00:00
year: 1993
type: Academic Article
type: Article
type: Document
type: Information Resource

Phorbol ester treatment inhibits phosphatidylinositol 3-kinase activation by, and association with, CD28, a T-lymphocyte surface receptor.
PubMed Identifier: 7568022
author list: Hutchcroft JE, Franklin DP, Tsai B, Harrison-Findik D, Varticovski L, Bierer BE
published in: Proceedings of the National Academy of Sciences of the United States of America
information resource reference: Phorbol ester treatment inhibits phosphatidylinositol 3-kinase activation by, and association with, CD28, a T-lymphocyte surface receptor. Proc Natl Acad Sci U S A. 1995 Sep 12; 92(19):8808-12.
journal title abbreviation: Proc Natl Acad Sci U S A
publication date: 1995-09-12T00:00:00
year: 1995
type: Academic Article
type: Article
type: Document
type: Information Resource

A role for calcineurin in degranulation of murine cytotoxic T lymphocytes.
PubMed Identifier: 7681074
author list: Dutz JP, Fruman DA, Burakoff SJ, Bierer BE
published in: Journal of immunology (Baltimore, Md. : 1950)
information resource reference: A role for calcineurin in degranulation of murine cytotoxic T lymphocytes. J Immunol. 1993 Apr 01; 150(7):2591-8.
journal title abbreviation: J Immunol
publication date: 1993-04-01T00:00:00
year: 1993
type: Academic Article
type: Article
type: Document
type: Information Resource

Signal transduction pathways involved in T cell receptor-induced regulation of CD2 avidity for CD58.
PubMed Identifier: 7681075
author list: Hahn WC, Burakoff SJ, Bierer BE
published in: Journal of immunology (Baltimore, Md. : 1950)
information resource reference: Signal transduction pathways involved in T cell receptor-induced regulation of CD2 avidity for CD58. J Immunol. 1993 Apr 01; 150(7):2607-19.
journal title abbreviation: J Immunol
publication date: 1993-04-01T00:00:00
year: 1993
type: Academic Article
type: Article
type: Document
type: Information Resource

Characterization of HTLV-I in vivo infected T cell clones. IL-2-independent growth of nontransformed T cells.
PubMed Identifier: 1374452
author list: Höllsberg P, Wucherpfennig KW, Ausubel LJ, Calvo V, Bierer BE, Hafler DA
published in: Journal of immunology (Baltimore, Md. : 1950)
information resource reference: Characterization of HTLV-I in vivo infected T cell clones. IL-2-independent growth of nontransformed T cells. J Immunol. 1992 May 15; 148(10):3256-63.
journal title abbreviation: J Immunol
publication date: 1992-05-15T00:00:00
year: 1992
type: Academic Article
type: Article
type: Document
type: Information Resource

T3 glycoprotein is functional although structurally distinct on human T-cell receptor gamma T lymphocytes.
PubMed Identifier: 3108880
author list: Krangel MS, Bierer BE, Devlin P, Clabby M, Strominger JL, McLean J, Brenner MB
published in: Proceedings of the National Academy of Sciences of the United States of America
information resource reference: T3 glycoprotein is functional although structurally distinct on human T-cell receptor gamma T lymphocytes. Proc Natl Acad Sci U S A. 1987 Jun; 84(11):3817-21.
journal title abbreviation: Proc Natl Acad Sci U S A
publication date: 1987-06-01T00:00:00
year: 1987
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1129004
type: Authorship
author rank in publication: 1
linked author: Bierer, Barbara
linked information resource: The Revised and Final Common Rule: An Unfinished Story.

The Revised and Final Common Rule: An Unfinished Story.
PubMed Identifier: 30707525
author list: Bierer BE
published in: IRB
information resource reference: The Revised and Final Common Rule: An Unfinished Story. IRB. 2017 Nov-Dec; 39(6):6-10.
journal title abbreviation: IRB
publication date: 2017-11-01T00:00:00
year: 2017
type: Academic Article
type: Article
type: Document
type: Information Resource

Adhesion receptors in lymphocyte activation.
PubMed Identifier: 7917106
author list: Collins TL, Kassner PD, Bierer BE, Burakoff SJ
published in: Current opinion in immunology
information resource reference: Adhesion receptors in lymphocyte activation. Curr Opin Immunol. 1994 Jun; 6(3):385-93.
journal title abbreviation: Curr Opin Immunol
publication date: 1994-06-01T00:00:00
year: 1994
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1138945
type: Authorship
author rank in publication: 7
linked author: Bierer, Barbara
linked information resource: Transitioning to the National Institutes of Health single institutional review board model: Piloting the use of the Streamlined, Multi-site, Accelerated Resources for Trials IRB Reliance.

Transitioning to the National Institutes of Health single institutional review board model: Piloting the use of the Streamlined, Multi-site, Accelerated Resources for Trials IRB Reliance.
PubMed Identifier: 30866676
author list: Vardeny O, Hernandez AF, Cohen LW, Franklin A, Baqai M, Palmer S, Bierer BE, Cobb N
published in: Clinical trials (London, England)
information resource reference: Transitioning to the National Institutes of Health single institutional review board model: Piloting the use of the Streamlined, Multi-site, Accelerated Resources for Trials IRB Reliance. Clin Trials. 2019 06; 16(3):290-296.
journal title abbreviation: Clin Trials
publication date: 2019-03-13T00:00:00
year: 2019
type: Academic Article
type: Article
type: Document
type: Information Resource

Scientific Misconduct
MeSH DescriptorUI: D015871
MeSH semantic group name: Concepts & Ideas
MeSH semantic group name: Phenomena
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number of publications: 84
uniqueness weight: 0.902506
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Clinical Trials as Topic
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Authorship 131560
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linked information resource: The adenomatous polyposis coli-binding protein EB1 is associated with cytoplasmic and spindle microtubules.

Authorship 131686
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linked author: Bierer, Barbara
linked information resource: Interleukin 2 stimulation of p70 S6 kinase activity is inhibited by the immunosuppressant rapamycin.

Mongan Institute's Health Policy Center - MIHPC
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Ethics Committees, Research
MeSH DescriptorUI: D028744
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number of publications: 209
uniqueness weight: 0.864618
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Authorship 115318
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linked author: Bierer, Barbara
linked information resource: The role of functional cell surface antigens in T cell activation.

Harvard Catalyst
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Member
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Biomedical Research
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MeSH semantic group name: Procedures
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Information Dissemination
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uniqueness weight: 0.537771
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Health Policy and Management
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Medicine
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Pediatrics
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Radiology
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Rheumatology
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Infectious Disease
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Oncology
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Pulmonary
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Division of Global Health Equity
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Beth Israel Deaconess Medical Center
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Brigham and Women's Hospital
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Boston Children's Hospital
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Dana-Farber Cancer Institute
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Harvard T.H. Chan School of Public Health
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Massachusetts General Hospital
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Gupta, Neil
eCommons Login: NG34
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last name: Gupta
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Hahn, William
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Rohloff, Peter
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Authorship 1156444
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linked information resource: Scientific Merit Predicates Ethical Review of Clinical Research.

Scientific Merit Predicates Ethical Review of Clinical Research.
PubMed Identifier: 31108574
author list: Bierer BE, Gelinas L
published in: Ethics & human research
information resource reference: Scientific Merit Predicates Ethical Review of Clinical Research. Ethics Hum Res. 2019 05; 41(3):29-32.
journal title abbreviation: Ethics Hum Res
publication date: 2019-05-01T00:00:00
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Iezzoni, Lisa
eCommons Login: LII2
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Drazen, Jeffrey
eCommons Login: JMD5
first name: Jeffrey
last name: Drazen
full name: Jeffrey Mark Drazen, M.D.
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latitude: 42.33520000000000
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Bourgeois, Florence
eCommons Login: FTB1
first name: Florence
last name: Bourgeois
full name: Florence Tanya Bourgeois, M.D.
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Authorship 1157714
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linked information resource: Social Media as an Ethical Tool for Retention in Clinical Trials.

Social Media as an Ethical Tool for Retention in Clinical Trials.
PubMed Identifier: 31135316
author list: Gelinas L, Bierer BE
published in: The American journal of bioethics : AJOB
information resource reference: Social Media as an Ethical Tool for Retention in Clinical Trials. Am J Bioeth. 2019 06; 19(6):62-64.
journal title abbreviation: Am J Bioeth
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Selig, Sara
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Tsokos, George
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Authorship 1159558
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linked information resource: Credit data generators for data reuse.

Credit data generators for data reuse.
PubMed Identifier: 31164773
author list: Pierce HH, Dev A, Statham E, Bierer BE
published in: Nature
information resource reference: Credit data generators for data reuse. Nature. 2019 06; 570(7759):30-32.
journal title abbreviation: Nature
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Ligibel, Jennifer
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Palazuelos, Daniel
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Lu, Weidong
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Weintraub, Rebecca
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Rubin, Eric
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linked information resource: Protecting Pregnant Women With Substance Use Disorders and Their Neonates Participating in Research.

Protecting Pregnant Women With Substance Use Disorders and Their Neonates Participating in Research.
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linked information resource: Relocation of study participants for rare and ultra-rare disease trials: Ethics and operations.

Relocation of study participants for rare and ultra-rare disease trials: Ethics and operations.
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linked information resource: Returning aggregate results of clinical trials: Empirical data of patient preferences.

Returning aggregate results of clinical trials: Empirical data of patient preferences.
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linked information resource: CD80 and CD86 are not equivalent in their ability to induce the tyrosine phosphorylation of CD28.

Authorship 1201488
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linked information resource: The SMART IRB platform: A national resource for IRB review for multisite studies.

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linked information resource: Development of a plain-language library of educational resources for research participants.

Development of a plain-language library of educational resources for research participants.
PubMed Identifier: 31660216
author list: Witte E, Winkler SJ, Myerson J, Kirby A, Biggers J, Do JM, Roth MT, Gateman AK, Cagliero E, Bierer BE
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The SMART IRB platform: A national resource for IRB review for multisite studies.
PubMed Identifier: 31660237
author list: Cobb N, Witte E, Cervone M, Kirby A, MacFadden D, Nadler L, Bierer BE
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linked information resource: A role for calcineurin in degranulation of murine cytotoxic T lymphocytes.

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linked information resource: Functional CD2 mutants unable to bind to, or be stimulated by, LFA-3.

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William Rosenberg Professor of Medicine
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Authorship 126745
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linked information resource: T cell regulation of p62(dok) (Dok1) association with Crk-L.

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linked information resource: Issues in the registration of database studies.

Authorship 1220339
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linked information resource: Research Subject Injury Compensation: The Ongoing Search for Fairness, Consistency and Clarity.

Research Subject Injury Compensation: The Ongoing Search for Fairness, Consistency and Clarity.
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Issues in the registration of database studies.
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Innovative statistical methodologies to subgroup analysis in clinical trials
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principal investigator name: BIERER, BARBARA E
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linked information resource: Leveling the Joint Task Force Core Competencies for Clinical Research Professionals.

Leveling the Joint Task Force Core Competencies for Clinical Research Professionals.
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linked information resource: Economic vulnerability and payment for research participation.

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linked information resource: Primed to comply: Individual participant data sharing statements on ClinicalTrials.gov.

Economic vulnerability and payment for research participation.
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Primed to comply: Individual participant data sharing statements on ClinicalTrials.gov.
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linked information resource: Time for NIH to lead on data sharing.

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linked information resource: Disruptive and avoidable: GDPR challenges to secondary research uses of data.

Time for NIH to lead on data sharing.
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Disruptive and avoidable: GDPR challenges to secondary research uses of data.
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information resource reference: Disruptive and avoidable: GDPR challenges to secondary research uses of data. Eur J Hum Genet. 2020 06; 28(6):697-705.
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linked information resource: Association of p59(fyn) with the T lymphocyte costimulatory receptor CD2. Binding of the Fyn Src homology (SH) 3 domain is regulated by the Fyn SH2 domain.

Innovation in biosafety oversight: The Harvard Catalyst Common Reciprocal IBC Reliance Authorization Agreement.
PubMed Identifier: 32313697
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information resource reference: Innovation in biosafety oversight: The Harvard Catalyst Common Reciprocal IBC Reliance Authorization Agreement. J Clin Transl Sci. 2020 Apr; 4(2):90-95.
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Facilitating collaborative animal research: The development and implementation of a Master Reciprocal Institutional Agreement for Animal Care and Use.
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author list: Holthaus K, Goldberg D, Connelly C, Corning B, Nascimento C, Witte E, Bierer BE
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information resource reference: Facilitating collaborative animal research: The development and implementation of a Master Reciprocal Institutional Agreement for Animal Care and Use. J Clin Transl Sci. 2020 Apr; 4(2):96-101.
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linked information resource: Facilitating collaborative animal research: The development and implementation of a Master Reciprocal Institutional Agreement for Animal Care and Use.

Authorship 1240578
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linked information resource: Innovation in biosafety oversight: The Harvard Catalyst Common Reciprocal IBC Reliance Authorization Agreement.

Authorship 205566
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linked information resource: Mechanisms of immunosuppression by FK506. Preservation of T cell transmembrane signal transduction.

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linked information resource: Aggregating data from COVID-19 trials.

Authorship 1255097
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linked information resource: Committing to the Inclusion of Diverse Populations in Clinical Research.

Committing to the Inclusion of Diverse Populations in Clinical Research.
PubMed Identifier: 32557312
author list: Ahmed HR, Strauss DH, Bierer BE
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Aggregating data from COVID-19 trials.
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linked information resource: Intracellular mediators regulate CD2 lateral diffusion and cytoplasmic Ca2+ mobilization upon CD2-mediated T cell activation.

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linked information resource: Patient-reported safety and quality of care in outpatient oncology.

Authorship 1292573
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linked information resource: How to fix the GDPR's frustration of global biomedical research.

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linked information resource: Rethinking ethical oversight in the era of the learning health system.

How to fix the GDPR's frustration of global biomedical research.
PubMed Identifier: 33004505
author list: Bovenberg J, Peloquin D, Bierer B, Barnes M, Knoppers BM
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Rethinking ethical oversight in the era of the learning health system.
PubMed Identifier: 32992106
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linked information resource: Inhibition of actin polymerization enhances commitment to and execution of apoptosis induced by withdrawal of trophic support.

Authorship 1302367
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linked information resource: Ethical Challenges in Clinical Research During the COVID-19 Pandemic.

Ethical Challenges in Clinical Research During the COVID-19 Pandemic.
PubMed Identifier: 33169251
author list: Bierer BE, White SA, Barnes JM, Gelinas L
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linked information resource: Raising standards for global data-sharing-Response.

Raising standards for global data-sharing-Response.
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information resource reference: Raising standards for global data-sharing-Response. Science. 2021 01 08; 371(6525):134-135.
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linked information resource: Real-World Evidence: Understanding Sources of Variability Through Empirical Analysis.

Real-World Evidence: Understanding Sources of Variability Through Empirical Analysis.
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information resource reference: Real-World Evidence: Understanding Sources of Variability Through Empirical Analysis. Value Health. 2021 01; 24(1):116-117.
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Global Cooperation to Promote Clinical Research in Children
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principal investigator name: BIERER, BARBARA E
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linked information resource: An ethics framework for consolidating and prioritizing COVID-19 clinical trials.

An ethics framework for consolidating and prioritizing COVID-19 clinical trials.
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information resource reference: An ethics framework for consolidating and prioritizing COVID-19 clinical trials. Clin Trials. 2021 04; 18(2):226-233.
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linked information resource: Dental Care in Times of the COVID-19 Pandemic: A Review.

Dental Care in Times of the COVID-19 Pandemic: A Review.
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information resource reference: Dental Care in Times of the COVID-19 Pandemic: A Review. Med Sci (Basel). 2021 02 19; 9(1).
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Justice, diversity, and research ethics review.
PubMed Identifier: 33737478
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information resource reference: Justice, diversity, and research ethics review. Science. 2021 Mar 19; 371(6535):1209-1211.
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linked information resource: Humoral hypercalcemia of malignancy. Release of a prostaglandin-stimulating bone-resorbing factor in vitro by human transitional-cell carcinoma cells.

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linked information resource: A Descriptive-Multivariate Analysis of Community Knowledge, Confidence, and Trust in COVID-19 Clinical Trials among Healthcare Workers in Uganda.

A Descriptive-Multivariate Analysis of Community Knowledge, Confidence, and Trust in COVID-19 Clinical Trials among Healthcare Workers in Uganda.
PubMed Identifier: 33809269
author list: Kasozi KI, Laudisoit A, Osuwat LO, Batiha GE, Al Omairi NE, Aigbogun E, Ninsiima HI, Usman IM, DeTora LM, MacLeod ET, Nalugo H, Crawley FP, Bierer BE, Mwandah DC, Kato CD, Kiyimba K, Ayikobua ET, Lillian L, Matama K, Nelly Mak SC, Onanyang D, Pius T, Nalumenya DP, Ssebuufu R, Rugambwa NO, Musoke GH, Bardosh K, Ochieng JJ, Ssempijja F, Kyamanywa P, Tumwine G, Alzahrani KJ, Welburn SC
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Authorship 1372064
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Online Research Participant Communication: Balancing Benefits and Risks.
PubMed Identifier: 34196504
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Navigating the ethics of remote research data collection.
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linked information resource: Advancing Health Literacy in Clinical Research: Clear Communications for Every Participant.

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linked information resource: Evaluating the frequency of English language requirements in clinical trial eligibility criteria: A systematic analysis using ClinicalTrials.gov.

Fair payment and just benefits to enhance diversity in clinical research.
PubMed Identifier: 34527298
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Evaluating the frequency of English language requirements in clinical trial eligibility criteria: A systematic analysis using ClinicalTrials.gov.
PubMed Identifier: 34520467
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information resource reference: Evaluating the frequency of English language requirements in clinical trial eligibility criteria: A systematic analysis using ClinicalTrials.gov. PLoS Med. 2021 09; 18(9):e1003758.
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Advancing Health Literacy in Clinical Research: Clear Communications for Every Participant.
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linked information resource: Testing approaches to sharing trial results with participants: The Show RESPECT cluster randomised, factorial, mixed methods trial.

Testing approaches to sharing trial results with participants: The Show RESPECT cluster randomised, factorial, mixed methods trial.
PubMed Identifier: 34606495
author list: South A, Joharatnam-Hogan N, Purvis C, James EC, Diaz-Montana C, Cragg WJ, Tweed C, Macnair A, Sydes MR, Snowdon C, Gillies K, Isaacs T, Bierer BE, Copas AJ
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Steps toward a System of IRB Precedent: Piloting Approaches to Summarizing IRB Decisions for Future Use.
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linked information resource: Integrating Supported Decision-Making into the Clinical Research Process.

Demystifying Schrems II for the cross-border transfer of clinical research data.
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Integrating Supported Decision-Making into the Clinical Research Process.
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Authorship 1412785
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linked information resource: Characterization of Informed Consent Forms Posted on ClinicalTrials.gov.

Characterization of Informed Consent Forms Posted on ClinicalTrials.gov.
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linked information resource: Allocation of Opportunities to Participate in Clinical Trials during the Covid-19 Pandemic and Other Public Health Emergencies.

Allocation of Opportunities to Participate in Clinical Trials during the Covid-19 Pandemic and Other Public Health Emergencies.
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linked information resource: Incorporating Competencies Related to Project Management into the Joint Taskforce Core Competency Framework for Clinical Research Professionals.

Incorporating Competencies Related to Project Management into the Joint Taskforce Core Competency Framework for Clinical Research Professionals.
PubMed Identifier: 34988928
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Hydroxychloroquine/chloroquine for the treatment of hospitalized patients with COVID-19: An individual participant data meta-analysis.
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linked information resource: Hydroxychloroquine/chloroquine for the treatment of hospitalized patients with COVID-19: An individual participant data meta-analysis.

Authorship 216559
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linked information resource: Correlation of calcineurin phosphatase activity and programmed cell death in murine T cell hybridomas.

Authorship 259444
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linked information resource: Two distinct signal transmission pathways in T lymphocytes are inhibited by complexes formed between an immunophilin and either FK506 or rapamycin.

Authorship 1440063
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linked information resource: Applying Civil Rights Law to Clinical Research: Title VI's Equal Access Mandate.

Authorship 1439587
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linked information resource: Self-assessed Competencies of Clinical Research Professionals and Recommendations for Further Education and Training.

Applying Civil Rights Law to Clinical Research: Title VI's Equal Access Mandate.
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Self-assessed Competencies of Clinical Research Professionals and Recommendations for Further Education and Training.
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linked information resource: IRBs and the Protection-Inclusion Dilemma: Finding a Balance.

Authorship 1447667
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linked information resource: Strategies to optimize inclusion of women in multi-national clinical trials.

Authorship 1446271
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linked information resource: Advancing the inclusion of underrepresented women in clinical research.

IRBs and the Protection-Inclusion Dilemma: Finding a Balance.
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Advancing the inclusion of underrepresented women in clinical research.
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Strategies to optimize inclusion of women in multi-national clinical trials.
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Authorship 1450704
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linked information resource: When Is a Change Significant? The Update Problem of Apps in Medical and Behavioral Research.

Authorship 1451161
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linked information resource: Implementing expanded COVID-19 testing in Massachusetts community health centers through community partnerships: Protocol for an interrupted time series and stepped wedge study design.

When Is a Change Significant? The Update Problem of Apps in Medical and Behavioral Research.
PubMed Identifier: 35543261
author list: Shachar C, Gerke S, Morrell W, Kirby A, Cohen IG, Bierer BE
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information resource reference: When Is a Change Significant? The Update Problem of Apps in Medical and Behavioral Research. Ethics Hum Res. 2022 May; 44(3):2-11.
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Implementing expanded COVID-19 testing in Massachusetts community health centers through community partnerships: Protocol for an interrupted time series and stepped wedge study design.
PubMed Identifier: 35533978
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information resource reference: Implementing expanded COVID-19 testing in Massachusetts community health centers through community partnerships: Protocol for an interrupted time series and stepped wedge study design. Contemp Clin Trials. 2022 07; 118:106783.
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first name: Elizabeth
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Authorship 377497
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linked information resource: The effect of desferrithiocin, an oral iron chelator, on T-cell function.

Authorship 1460578
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linked information resource: Developing a consensus-driven, plain-language clinical research glossary for study participants and the clinical research community.

Authorship 1459251
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linked information resource: Developing and implementing a self-monitoring toolkit for a coordinated multinational randomized acupuncture trial.

Developing and implementing a self-monitoring toolkit for a coordinated multinational randomized acupuncture trial.
PubMed Identifier: 35715806
author list: Baedorf Kassis S, Lu W, White SA, Shin IH, Park SH, Jeong YJ, Yao C, Ligibel J, Bierer BE
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Developing a consensus-driven, plain-language clinical research glossary for study participants and the clinical research community.
PubMed Identifier: 35651963
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Authorship 41203
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Authorship 1500091
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linked information resource: An Externalist, Process-Based Approach to Supported Decision-Making.

Authorship 1493083
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Authorship 1501170
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linked information resource: Excluding People With Disabilities From Clinical Research: Eligibility Criteria Lack Clarity And Justification.

Authorship 1494444
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linked information resource: Acupuncture for hot flashes in hormone receptor-positive breast cancer, a coordinated multinational study: Rationale and design of the study protocol.

Authorship 1493742
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linked information resource: Supported decision-making can advance clinical research participation for people with disabilities.

Authorship 1500718
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linked information resource: Hydroxychloroquine/chloroquine for the treatment of hospitalized patients with COVID-19: An individual participant data meta-analysis.

https://connects.catalyst.harvard.edu/Profiles/profile/203395823
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Supported decision-making can advance clinical research participation for people with disabilities.
PubMed Identifier: 36271167
author list: Silverman BC, Ne'eman A, Strauss DH, DeCormier Plosky W, Francis LP, Stein MA, Bierer BE
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information resource reference: Supported decision-making can advance clinical research participation for people with disabilities. Nat Med. 2022 11; 28(11):2250-2253.
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Hydroxychloroquine/chloroquine for the treatment of hospitalized patients with COVID-19: An individual participant data meta-analysis.
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information resource reference: Hydroxychloroquine/chloroquine for the treatment of hospitalized patients with COVID-19: An individual participant data meta-analysis. PLoS One. 2022; 17(9):e0273526.
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Acupuncture for hot flashes in hormone receptor-positive breast cancer, a coordinated multinational study: Rationale and design of the study protocol.
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information resource reference: Acupuncture for hot flashes in hormone receptor-positive breast cancer, a coordinated multinational study: Rationale and design of the study protocol. Contemp Clin Trials. 2022 10; 121:106885.
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Excluding People With Disabilities From Clinical Research: Eligibility Criteria Lack Clarity And Justification.
PubMed Identifier: 36190895
author list: DeCormier Plosky W, Ne'eman A, Silverman BC, Strauss DH, Francis LP, Stein MA, Bierer BE
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An Externalist, Process-Based Approach to Supported Decision-Making.
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Authorship 443068
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Authorship 456828
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linked information resource: The involvement of the proto-oncogene p120 c-Cbl and ZAP-70 in CD2-mediated T cell activation.

Authorship 1509468
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linked information resource: Protecting the Vulnerable and Including the Under-Represented: IRB Practices and Attitudes.

Protecting the Vulnerable and Including the Under-Represented: IRB Practices and Attitudes.
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linked information resource: Ensuring the Scientific Value and Feasibility of Clinical Trials: A Qualitative Interview Study.

Ensuring the Scientific Value and Feasibility of Clinical Trials: A Qualitative Interview Study.
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linked information resource: Structural organization of the genes encoding human and murine FK506-binding protein (FKBP) 13 and comparison to FKBP1.

Authorship 1522016
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linked information resource: Establishing a global regulatory floor for children's decisions about participation in clinical research.

Establishing a global regulatory floor for children's decisions about participation in clinical research.
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linked information resource: Treatment of chronic graft-versus-host disease with clofazimine.

Authorship 1563216
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linked information resource: Data sharing in the context of community-engaged research partnerships.

Authorship 1572264
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linked information resource: Implementation of single IRB review for multisite human subjects research: Persistent challenges and possible solutions.

Authorship 1561646
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Authorship 1558014
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linked information resource: Terms and conditions apply: an ethical analysis of mobile health user agreements in research.

Authorship 1562995
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author rank in publication: 4
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linked information resource: How to limit uninformative trials: Results from a Delphi working group.

Authorship 1557264
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author rank in publication: 27
linked author: Bierer, Barbara
linked information resource: Returning Individual Research Results from Digital Phenotyping in Psychiatry.

Authorship 1570672
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linked information resource: Data visualization explorer: A tool for participant representation in pivotal trials of FDA-approved medicinal products.

Authorship 1571998
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linked information resource: Losartan in hospitalized patients with COVID-19 in North America: An individual participant data meta-analysis.

Implementation of single IRB review for multisite human subjects research: Persistent challenges and possible solutions.
PubMed Identifier: 37250991
author list: Green JM, Goodman P, Kirby A, Cobb N, Bierer BE
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How to limit uninformative trials: Results from a Delphi working group.
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author list: Gelinas L, Hutchinson N, Zarin DA, Bierer BE
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Data visualization explorer: A tool for participant representation in pivotal trials of FDA-approved medicinal products.
PubMed Identifier: 37223273
author list: Carmeli AB, Meloney L, Bierer BE
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information resource reference: Data visualization explorer: A tool for participant representation in pivotal trials of FDA-approved medicinal products. Patterns (N Y). 2023 May 12; 4(5):100713.
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Terms and conditions apply: an ethical analysis of mobile health user agreements in research.
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author list: Gelinas L, Morrell W, Bierer BE
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information resource reference: Terms and conditions apply: an ethical analysis of mobile health user agreements in research. J Law Biosci. 2023 Jul-Dec; 10(2):lsad021.
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Disclosure of Possible Trial Termination to Participants of Interventional Clinical Trials.
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information resource reference: Disclosure of Possible Trial Termination to Participants of Interventional Clinical Trials. JAMA. 2023 04 04; 329(13):1116-1117.
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Returning Individual Research Results from Digital Phenotyping in Psychiatry.
PubMed Identifier: 37155651
author list: Shen FX, Baum ML, Martinez-Martin N, Miner AS, Abraham M, Brownstein CA, Cortez N, Evans BJ, Germine LT, Glahn DC, Grady C, Holm IA, Hurley EA, Kimble S, Lázaro-Muñoz G, Leary K, Marks M, Monette PJ, Onnela JP, O'Rourke PP, Rauch SL, Shachar C, Sen S, Vahia I, Vassy JL, Baker JT, Bierer BE, Silverman BC
published in: The American journal of bioethics : AJOB
information resource reference: Returning Individual Research Results from Digital Phenotyping in Psychiatry. Am J Bioeth. 2024 Feb; 24(2):69-90.
journal title abbreviation: Am J Bioeth
publication date: 2023-05-08T00:00:00
year: 2023
type: Academic Article
type: Article
type: Document
type: Information Resource

Data sharing in the context of community-engaged research partnerships.
PubMed Identifier: 37062144
author list: Emmons KM, Mendez S, Lee RM, Erani D, Mascioli L, Abreu M, Adams S, Daly J, Bierer BE
published in: Social science & medicine (1982)
information resource reference: Data sharing in the context of community-engaged research partnerships. Soc Sci Med. 2023 05; 325:115895.
journal title abbreviation: Soc Sci Med
publication date: 2023-04-11T00:00:00
year: 2023
type: Academic Article
type: Article
type: Document
type: Information Resource

Losartan in hospitalized patients with COVID-19 in North America: An individual participant data meta-analysis.
PubMed Identifier: 37335665
author list: Di Stefano L, Ram M, Scharfstein DO, Li T, Khanal P, Baksh SN, McBee N, Bengtson CD, Gadomski A, Geriak M, Puskarich MA, Salathe MA, Schutte AE, Tignanelli CJ, Victory J, Bierer BE, Hanley DF, Freilich DA
published in: Medicine
information resource reference: Losartan in hospitalized patients with COVID-19 in North America: An individual participant data meta-analysis. Medicine (Baltimore). 2023 Jun 09; 102(23):e33904.
journal title abbreviation: Medicine (Baltimore)
publication date: 2023-06-09T00:00:00
year: 2023
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 283157
type: Authorship
author rank in publication: 4
linked author: Bierer, Barbara
linked information resource: Characterization of a mutant calcineurin A alpha gene expressed by EL4 lymphoma cells.

Authorship 234841
type: Authorship
author rank in publication: 14
linked author: Bierer, Barbara
linked information resource: High-dose cyclophosphamide, carmustine, and etoposide with autologous transplantation in Hodgkin's disease: a prognostic model for treatment outcomes.

Authorship 1590315
type: Authorship
author rank in publication: 1
linked author: Bierer, Barbara
linked information resource: The Unresolved Challenge of Triage.

Authorship 1590543
type: Authorship
author rank in publication: 5
linked author: Bierer, Barbara
linked information resource: Acknowledging Complexity and Reimagining IRBs: A Reply to Discussions of the Protection-Inclusion Dilemma.

Authorship 1582795
type: Authorship
author rank in publication: 6
linked author: Bierer, Barbara
linked information resource: Characterization of key information sections in informed consent forms posted on ClinicalTrials.gov.

Authorship 1593527
type: Authorship
author rank in publication: 3
linked author: Bierer, Barbara
linked information resource: Enhancing diversity of clinical trial populations in multiple sclerosis.

Authorship 1584562
type: Authorship
author rank in publication: 3
linked author: Bierer, Barbara
linked information resource: Review of diversity, equity, and inclusion by ethics committees: A Delphi consensus statement.

Authorship 1582958
type: Authorship
author rank in publication: 3
linked author: Bierer, Barbara
linked information resource: Site staff perspectives on communicating trial results to participants: Cost and feasibility results from the Show RESPECT cluster randomised, factorial, mixed-methods trial.

Authorship 1587420
type: Authorship
author rank in publication: 4
linked author: Bierer, Barbara
linked information resource: Defining "recklessness" in research misconduct proceedings.

Site staff perspectives on communicating trial results to participants: Cost and feasibility results from the Show RESPECT cluster randomised, factorial, mixed-methods trial.
PubMed Identifier: 37515519
author list: South A, Bailey J, Bierer BE, Burnett E, Cragg WJ, Diaz-Montana C, Gillies K, Isaacs T, Joharatnam-Hogan N, Snowdon C, Sydes MR, Copas AJ
published in: Clinical trials (London, England)
information resource reference: Site staff perspectives on communicating trial results to participants: Cost and feasibility results from the Show RESPECT cluster randomised, factorial, mixed-methods trial. Clin Trials. 2023 12; 20(6):649-660.
journal title abbreviation: Clin Trials
publication date: 2023-07-29T00:00:00
year: 2023
type: Academic Article
type: Article
type: Document
type: Information Resource

Enhancing diversity of clinical trial populations in multiple sclerosis.
PubMed Identifier: 37555490
author list: Marrie RA, Chataway J, Bierer BE, Finlayson M, Martinez-Lapiscina EH, Panagoulias J, Sormani MP, Williams MJ, Amezcua L
published in: Multiple sclerosis (Houndmills, Basingstoke, England)
information resource reference: Enhancing diversity of clinical trial populations in multiple sclerosis. Mult Scler. 2023 08; 29(9):1174-1185.
journal title abbreviation: Mult Scler
publication date: 2023-08-01T00:00:00
year: 2023
type: Academic Article
type: Article
type: Document
type: Information Resource

Review of diversity, equity, and inclusion by ethics committees: A Delphi consensus statement.
PubMed Identifier: 37572650
author list: Meloney LG, Ahmed H, Bierer BE
published in: Med (New York, N.Y.)
information resource reference: Review of diversity, equity, and inclusion by ethics committees: A Delphi consensus statement. Med. 2023 08 11; 4(8):497-504.
journal title abbreviation: Med
publication date: 2023-08-11T00:00:00
year: 2023
type: Academic Article
type: Article
type: Document
type: Information Resource

The Unresolved Challenge of Triage.
PubMed Identifier: 37642969
author list: Bierer BE, Truog RD
published in: JAMA network open
information resource reference: The Unresolved Challenge of Triage. JAMA Netw Open. 2023 08 01; 6(8):e2329676.
journal title abbreviation: JAMA Netw Open
publication date: 2023-08-01T00:00:00
year: 2023
type: Academic Article
type: Article
type: Document
type: Information Resource

Acknowledging Complexity and Reimagining IRBs: A Reply to Discussions of the Protection-Inclusion Dilemma.
PubMed Identifier: 37647484
author list: Friesen P, Gelinas L, Kirby A, Strauss DH, Bierer BE
published in: The American journal of bioethics : AJOB
information resource reference: Acknowledging Complexity and Reimagining IRBs: A Reply to Discussions of the Protection-Inclusion Dilemma. Am J Bioeth. 2023 09; 23(9):W1-W8.
journal title abbreviation: Am J Bioeth
publication date: 2023-09-01T00:00:00
year: 2023
type: Academic Article
type: Article
type: Document
type: Information Resource

Defining "recklessness" in research misconduct proceedings.
PubMed Identifier: 37694962
author list: Caron MM, Dohan SB, Barnes M, Bierer BE
published in: Accountability in research
information resource reference: Defining "recklessness" in research misconduct proceedings. Account Res. 2025 02; 32(2):120-142.
journal title abbreviation: Account Res
publication date: 2023-09-18T00:00:00
year: 2023
type: Academic Article
type: Article
type: Document
type: Information Resource

Characterization of key information sections in informed consent forms posted on ClinicalTrials.gov.
PubMed Identifier: 37745937
author list: Gelinas L, Morrell W, Tse T, Glazier A, Zarin DA, Bierer BE
published in: Journal of clinical and translational science
information resource reference: Characterization of key information sections in informed consent forms posted on ClinicalTrials.gov. J Clin Transl Sci. 2023; 7(1):e185.
journal title abbreviation: J Clin Transl Sci
publication date: 2023-08-14T00:00:00
year: 2023
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1594747
type: Authorship
author rank in publication: 1
linked author: Bierer, Barbara
linked information resource: Deprioritization of Ongoing Clinical Trials.

Deprioritization of Ongoing Clinical Trials.
PubMed Identifier: 37777980
author list: Bierer BE, Zarin DA, Gelinas L
published in: Ethics & human research
information resource reference: Deprioritization of Ongoing Clinical Trials. Ethics Hum Res. 2023 Sep-Oct; 45(5):27-33.
journal title abbreviation: Ethics Hum Res
publication date: 2023-09-01T00:00:00
year: 2023
type: Academic Article
type: Article
type: Document
type: Information Resource

Associate Professor of Medicine
is primary position: true
position in department: Medicine
position in division: Division of Global Health Equity
sort order: 1
type: Position
HR job title: Associate Professor of Medicine
position in organization: Brigham and Women's Hospital

Authorship 190536
type: Authorship
author rank in publication: 2
linked author: Bierer, Barbara
linked information resource: Molecular and biological actions of cyclosporin A and FK506 on T cell development and function.

Authorship 49591
type: Authorship
author rank in publication: 8
linked author: Bierer, Barbara
linked information resource: Bone marrow transplantation for therapy-related myelodysplasia: comparison with primary myelodysplasia.

Authorship 540684
type: Authorship
author rank in publication: 5
linked author: Bierer, Barbara
linked information resource: Failure of gelsolin overexpression to regulate lymphocyte apoptosis.

Authorship 552684
type: Authorship
author rank in publication: 4
linked author: Bierer, Barbara
linked information resource: Interaction of CD2 with its ligand lymphocyte function-associated antigen-3 induces adenosine 3',5'-cyclic monophosphate production in T lymphocytes.

Authorship 1625269
type: Authorship
author rank in publication: 4
linked author: Bierer, Barbara
linked information resource: Education and training of clinical research professionals and the evolution of the Joint Task Force for Clinical Trial Competency.

Education and training of clinical research professionals and the evolution of the Joint Task Force for Clinical Trial Competency.
PubMed Identifier: 38303986
author list: Sonstein SA, Silva H, Jones CT, Bierer BE
published in: Frontiers in pharmacology
information resource reference: Education and training of clinical research professionals and the evolution of the Joint Task Force for Clinical Trial Competency. Front Pharmacol. 2024; 15:1291675.
journal title abbreviation: Front Pharmacol
publication date: 2024-01-18T00:00:00
year: 2024
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 217133
type: Authorship
author rank in publication: 1
linked author: Bierer, Barbara
linked information resource: FK 506 and rapamycin: molecular probes of T-lymphocyte activation.

Authorship 1630381
type: Authorship
author rank in publication: 1
linked author: Bierer, Barbara
linked information resource: Ethical Considerations in Decentralized Clinical Trials.

Ethical Considerations in Decentralized Clinical Trials.
PubMed Identifier: 38427177
author list: Bierer BE, White SA
published in: Journal of bioethical inquiry
information resource reference: Ethical Considerations in Decentralized Clinical Trials. J Bioeth Inq. 2023 12; 20(4):711-718.
journal title abbreviation: J Bioeth Inq
publication date: 2024-03-01T00:00:00
year: 2024
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 532281
type: Authorship
author rank in publication: 1
linked author: Bierer, Barbara
linked information resource: T cell adhesion, avidity regulation and signaling: a molecular analysis of CD2.

Authorship 1647048
type: Authorship
author rank in publication: 5
linked author: Bierer, Barbara
linked information resource: First, do no harm: a global perspective on diversity and inclusion in clinical trials.

Authorship 1653823
type: Authorship
author rank in publication: 4
linked author: Bierer, Barbara
linked information resource: A Federally Qualified Health Center-led Ethics & Equity Framework & Workflow Checklist: An Invited Commentary in Response to a Relational Public Health Framing of FQHCs During COVID-19.

First, do no harm: a global perspective on diversity and inclusion in clinical trials.
PubMed Identifier: 38720005
author list: Wright K, DeCormier Plosky W, Ahmed HR, White SA, Bierer BE
published in: Nature reviews. Drug discovery
information resource reference: First, do no harm: a global perspective on diversity and inclusion in clinical trials. Nat Rev Drug Discov. 2024 07; 23(7):481-482.
journal title abbreviation: Nat Rev Drug Discov
publication date: 2024-07-01T00:00:00
year: 2024
type: Academic Article
type: Article
type: Document
type: Information Resource

A Federally Qualified Health Center-led Ethics & Equity Framework & Workflow Checklist: An Invited Commentary in Response to a Relational Public Health Framing of FQHCs During COVID-19.
PubMed Identifier: 38818590
author list: Torres CH, Kassis SB, Sayeed S, Bierer BE, Emmons KM
published in: The Journal of law, medicine & ethics : a journal of the American Society of Law, Medicine & Ethics
information resource reference: A Federally Qualified Health Center-led Ethics & Equity Framework & Workflow Checklist: An Invited Commentary in Response to a Relational Public Health Framing of FQHCs During COVID-19. J Law Med Ethics. 2024; 52(1):41-44.
journal title abbreviation: J Law Med Ethics
publication date: 2024-05-31T00:00:00
year: 2024
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1660194
type: Authorship
author rank in publication: 3
linked author: Bierer, Barbara
linked information resource: Proposed Increases in Government Authority Over Research Misconduct Proceedings.

Authorship 1657929
type: Authorship
author rank in publication: 14
linked author: Bierer, Barbara
linked information resource: Acupuncture for hot flashes in hormone receptor-positive breast cancer: A pooled analysis of individual patient data from parallel randomized trials.

Authorship 1658314
type: Authorship
author rank in publication: 4
linked author: Bierer, Barbara
linked information resource: An investigation into gender distributions in scholarly publications among dental faculty members in Iran.

Authorship 343269
type: Authorship
author rank in publication: 2
linked author: Bierer, Barbara
linked information resource: T cell receptor activation of a ribosomal S6 kinase activity.

An investigation into gender distributions in scholarly publications among dental faculty members in Iran.
PubMed Identifier: 38935641
author list: Sofi-Mahmudi A, Shamsoddin E, DeTora LM, Bierer BE, Ekmekci PE, Folayan MO, Lii CS, Tovani-Palone MR, Crawley FP
published in: PloS one
information resource reference: An investigation into gender distributions in scholarly publications among dental faculty members in Iran. PLoS One. 2024; 19(6):e0300698.
journal title abbreviation: PLoS One
publication date: 2024-06-27T00:00:00
year: 2024
type: Academic Article
type: Article
type: Document
type: Information Resource

Proposed Increases in Government Authority Over Research Misconduct Proceedings.
PubMed Identifier: 38900488
author list: Caron MM, Barnes M, Bierer BE
published in: JAMA
information resource reference: Proposed Increases in Government Authority Over Research Misconduct Proceedings. JAMA. 2024 07 16; 332(3):193-194.
journal title abbreviation: JAMA
publication date: 2024-07-16T00:00:00
year: 2024
type: Academic Article
type: Article
type: Document
type: Information Resource

Acupuncture for hot flashes in hormone receptor-positive breast cancer: A pooled analysis of individual patient data from parallel randomized trials.
PubMed Identifier: 38924035
author list: Lu W, Giobbie-Hurder A, Tanasijevic A, Kassis SB, Park SH, Jeong YJ, Shin IH, Yao C, Jung HJ, Zhu Z, Bao C, Bao T, Yang E, Bierer BE, Ligibel JA
published in: Cancer
information resource reference: Acupuncture for hot flashes in hormone receptor-positive breast cancer: A pooled analysis of individual patient data from parallel randomized trials. Cancer. 2024 Sep 15; 130(18):3219-3228.
journal title abbreviation: Cancer
publication date: 2024-06-24T00:00:00
year: 2024
type: Academic Article
type: Article
type: Document
type: Information Resource

Instructor in Medicine
is primary position: true
position in department: Medicine
position in division: Oncology
sort order: 1
type: Position
HR job title: Instructor in Medicine
position in organization: Dana-Farber Cancer Institute

Ne'eman, Ari
eCommons Login: AN240
first name: Ari
last name: Ne'eman
full name: Ari Ne'eman, Ph.D.
has faculty rank: Assistant Professor
photo: https://connects.catalyst.harvard.edu/Profiles/profile/Modules/CustomViewPersonGeneralInfo/PhotoHandler.ashx
Person ID: 185637
person in primary position: Assistant Professor of Health Policy and Management
type: Agent
type: Person
preferred title: Assistant Professor of Health Policy and Management

Authorship 1665522
type: Authorship
author rank in publication: 4
linked author: Bierer, Barbara
linked information resource: The SHOW RESPECT adaptable framework of considerations for planning how to share trial results with participants, based on qualitative findings from trial participants and site staff.

The SHOW RESPECT adaptable framework of considerations for planning how to share trial results with participants, based on qualitative findings from trial participants and site staff.
PubMed Identifier: 38982441
author list: South A, Snowdon C, Burnett E, Bierer BE, Gillies K, Isaacs T, Sydes MR
published in: Trials
information resource reference: The SHOW RESPECT adaptable framework of considerations for planning how to share trial results with participants, based on qualitative findings from trial participants and site staff. Trials. 2024 Jul 10; 25(1):467.
journal title abbreviation: Trials
publication date: 2024-07-10T00:00:00
year: 2024
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 377103
type: Authorship
author rank in publication: 5
linked author: Bierer, Barbara
linked information resource: Prognostic factors for treatment outcome in autotransplantation of intermediate-grade and high-grade non-Hodgkin's lymphoma with cyclophosphamide, carmustine, and etoposide.

Authorship 173881
type: Authorship
author rank in publication: 5
linked author: Bierer, Barbara
linked information resource: Activation of 70-kDa S6 kinase, induced by the cytokines interleukin-3 and erythropoietin and inhibited by rapamycin, is not an absolute requirement for cell proliferation.

Authorship 1668974
type: Authorship
author rank in publication: 3
linked author: Bierer, Barbara
linked information resource: Editorial: Building the clinical research workforce: challenges, capacities and competencies.

Editorial: Building the clinical research workforce: challenges, capacities and competencies.
PubMed Identifier: 39081959
author list: Jones CT, Johnson E, Bierer BE, Snyder DC, Smith HA, Akuffo E, Sonstein S
published in: Frontiers in pharmacology
information resource reference: Editorial: Building the clinical research workforce: challenges, capacities and competencies. Front Pharmacol. 2024; 15:1446908.
journal title abbreviation: Front Pharmacol
publication date: 2024-07-16T00:00:00
year: 2024
type: Academic Article
type: Article
type: Document
type: Information Resource

Instructor in Medicine
is primary position: true
position in department: Medicine
position in division: Division of Global Health Equity
sort order: 1
type: Position
HR job title: Instructor in Medicine
position in organization: Brigham and Women's Hospital

Professor of Medicine (Pediatrics)
is primary position: true
position in department: Medicine
position in division: Division of Global Health Equity
sort order: 1
type: Position
HR job title: Professor of Medicine (Pediatrics)
position in organization: Brigham and Women's Hospital

Associate Professor of Medicine
is primary position: true
position in department: Medicine
position in division: Division of Global Health Equity
sort order: 1
type: Position
HR job title: Associate Professor of Medicine
position in organization: Brigham and Women's Hospital

Clinical Fellow in Radiology
is primary position: true
position in department: Radiology
position in division: https://connects.catalyst.harvard.edu/Profiles/profile/1229413
sort order: 1
type: Position
HR job title: Clinical Fellow in Radiology
position in organization: Beth Israel Deaconess Medical Center

Authorship 30588
type: Authorship
author rank in publication: 2
linked author: Bierer, Barbara
linked information resource: Depletion of bone marrow T-lymphocytes with an anti-CD5 monoclonal immunotoxin (ST-1 immunotoxin): effective prophylaxis for graft-versus-host disease.

Authorship 328204
type: Authorship
author rank in publication: 2
linked author: Bierer, Barbara
linked information resource: A study of induced hyponatremia in the prevention and treatment of sickle-cell crisis.

Authorship 1683446
type: Authorship
author rank in publication: 3
linked author: Bierer, Barbara
linked information resource: The PubPeer conundrum: Administrative challenges in research misconduct proceedings.

The PubPeer conundrum: Administrative challenges in research misconduct proceedings.
PubMed Identifier: 39138003
author list: Caron MM, Lye CT, Bierer BE, Barnes M
published in: Accountability in research
information resource reference: The PubPeer conundrum: Administrative challenges in research misconduct proceedings. Account Res. 2025 Nov; 32(8):1369-1387.
journal title abbreviation: Account Res
publication date: 2024-08-13T00:00:00
year: 2024
type: Academic Article
type: Article
type: Document
type: Information Resource

The Promise and Perils of Diversity Action Plans for Clinical Trials.
PubMed Identifier: 39302826
author list: Varma T, Bierer BE, Hantel A
published in: JAMA
information resource reference: The Promise and Perils of Diversity Action Plans for Clinical Trials. JAMA. 2024 Dec 03; 332(21):1787-1788.
journal title abbreviation: JAMA
publication date: 2024-12-03T00:00:00
year: 2024
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 347531
type: Authorship
author rank in publication: 3
linked author: Bierer, Barbara
linked information resource: CD4, CD8 and CD2 in T cell adhesion and signaling.

Authorship 642729
type: Authorship
author rank in publication: 2
linked author: Bierer, Barbara
linked information resource: Biomedical innovation in academic institutions: mitigating conflict of interest.

Biomedical innovation in academic institutions: mitigating conflict of interest.
PubMed Identifier: 21918104
author list: Nelsen LL, Bierer BE
published in: Science translational medicine
information resource reference: Biomedical innovation in academic institutions: mitigating conflict of interest. Sci Transl Med. 2011 Sep 14; 3(100):100cm26.
journal title abbreviation: Sci Transl Med
publication date: 2011-09-14T00:00:00
year: 2011
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1699799
type: Authorship
author rank in publication: 1
linked author: Bierer, Barbara
linked information resource: The Role of Institutional Review Boards in Improving the Inclusion of Sex and Gender as Variables in Clinical Research.

Authorship 1696245
type: Authorship
author rank in publication: 2
linked author: Bierer, Barbara
linked information resource: The Promise and Perils of Diversity Action Plans for Clinical Trials.

Authorship 1696065
type: Authorship
author rank in publication: 1
linked author: Bierer, Barbara
linked information resource: Declaration of Helsinki-Revisions for the 21st Century.

The Role of Institutional Review Boards in Improving the Inclusion of Sex and Gender as Variables in Clinical Research.
PubMed Identifier: 39298659
author list: Bierer BE
published in: The Journal of bone and joint surgery. American volume
information resource reference: The Role of Institutional Review Boards in Improving the Inclusion of Sex and Gender as Variables in Clinical Research. J Bone Joint Surg Am. 2024 Sep 18; 106(18):1718-1722.
journal title abbreviation: J Bone Joint Surg Am
publication date: 2024-08-01T00:00:00
year: 2024
type: Academic Article
type: Article
type: Document
type: Information Resource

Declaration of Helsinki-Revisions for the 21st Century.
PubMed Identifier: 39425949
author list: Bierer BE
published in: JAMA
information resource reference: Declaration of Helsinki-Revisions for the 21st Century. JAMA. 2025 Jan 07; 333(1):18-19.
journal title abbreviation: JAMA
publication date: 2025-01-07T00:00:00
year: 2025
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 199502
type: Authorship
author rank in publication: 3
linked author: Bierer, Barbara
linked information resource: CD28/CTLA-4 and CD80/CD86 families: signaling and function.

Authorship 1708595
type: Authorship
author rank in publication: 1
linked author: Bierer, Barbara
linked information resource: Engaging children and adolescents in the design and conduct of paediatric research.

Engaging children and adolescents in the design and conduct of paediatric research.
PubMed Identifier: 39600960
author list: Bierer BE, Koppelman E, Croker AK, Hosseinzadeh S, Hovinga C, Joffe S, McMillan G, Nelson R, Bucci-Rechtweg C
published in: Frontiers in pediatrics
information resource reference: Engaging children and adolescents in the design and conduct of paediatric research. Front Pediatr. 2024; 12:1481754.
journal title abbreviation: Front Pediatr
publication date: 2024-11-12T00:00:00
year: 2024
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 515303
type: Authorship
author rank in publication: 3
linked author: Bierer, Barbara
linked information resource: Adhesion receptors in lymphocyte activation.

Authorship 546817
type: Authorship
author rank in publication: 5
linked author: Bierer, Barbara
linked information resource: Tacrolimus (FK506) in allogeneic bone marrow transplantation for severe aplastic anemia following orthotopic liver transplantation.

The roadmap to integrate diversity, equity, and inclusion in hematology clinical trials: an American Society of Hematology initiative.
PubMed Identifier: 39652409
author list: Kuaban A, Croker AK, Keefer J, Valentino LA, Bierer BE, Boateng S, DiMichele D, Fogarty P, Gibson CM, Hood AM, Hubbard L, Isgrò A, Knobe K, Lake L, Martin I, Reid M, Roberts JC, Tomlinson W, Tunji-Ajayi L, Van Spall HGC, Voltz-Girolt C, Wheeler AP, Mast AE, Seremetis S
published in: Blood advances
information resource reference: The roadmap to integrate diversity, equity, and inclusion in hematology clinical trials: an American Society of Hematology initiative. Blood Adv. 2025 Feb 25; 9(4):687-695.
journal title abbreviation: Blood Adv
publication date: 2025-02-25T00:00:00
year: 2025
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 203390
type: Authorship
author rank in publication: 3
linked author: Bierer, Barbara
linked information resource: Immunosuppressants FK506 and rapamycin function as reversal agents of the multidrug resistance phenotype.

Authorship 1715262
type: Authorship
author rank in publication: 5
linked author: Bierer, Barbara
linked information resource: The roadmap to integrate diversity, equity, and inclusion in hematology clinical trials: an American Society of Hematology initiative.

Determining the Optimal Pathway for Clinical Trial Management at Montefiore/Einstein
end date: 2013-08-08T00:00:00
start date: 2013-06-13T00:00:00
type: Mentoring - Completed Student Project
overview: Summer

Authorship 1724394
type: Authorship
author rank in publication: 4
linked author: Bierer, Barbara
linked information resource: Persistent exclusion of non-English speakers in Pediatric research: a national analysis using ClinicalTrials.gov.

Persistent exclusion of non-English speakers in Pediatric research: a national analysis using ClinicalTrials.gov.
PubMed Identifier: 39843774
author list: Muthukumar AV, Shah KM, Glynn RJ, Bierer BE
published in: Pediatric research
information resource reference: Persistent exclusion of non-English speakers in Pediatric research: a national analysis using ClinicalTrials.gov. Pediatr Res. 2025 Sep; 98(3):839-843.
journal title abbreviation: Pediatr Res
publication date: 2025-01-22T00:00:00
year: 2025
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 681483
type: Authorship
author rank in publication: 5
linked author: Bierer, Barbara
linked information resource: Preparing for responsible sharing of clinical trial data.

Preparing for responsible sharing of clinical trial data.
PubMed Identifier: 24144394
author list: Mello MM, Francer JK, Wilenzick M, Teden P, Bierer BE, Barnes M
published in: The New England journal of medicine
information resource reference: Preparing for responsible sharing of clinical trial data. N Engl J Med. 2013 Oct 24; 369(17):1651-8.
journal title abbreviation: N Engl J Med
publication date: 2013-10-21T00:00:00
year: 2013
type: Academic Article
type: Article
type: Document
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Authorship 164933
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Defamation Claims Arising from Research Misconduct Cases: Best Practices for Institutions.
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A global call to action for disability inclusion in health research.
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Financial Toxicity in Cancer Clinical Trials: An Issue in Need of Clarity and Solutions.
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Managing Multi-Institutional Jurisdiction in Cases of Research Misconduct.
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Benefits that Offset Research Risks and Burdens are Qualitatively Different.
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An Analysis of Institutional Review Board Policies for Enrollment of Adults with Impaired or Uncertain Decision-Making Capacity.
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Advocating for collaboration among key partners to promote diversity in clinical studies amid policy challenges in the United States of America.
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Assessing Federal Policies to Reduce Economic Barriers to Clinical Trial Enrollment.
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Authorship 46488
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linked information resource: Mechanisms of action of immunosuppressive agents: cyclosporin A, FK506, and rapamycin.

Authorship 234863
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linked information resource: The biologic roles of CD2, CD4, and CD8 in T-cell activation.

Authorship 207698
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linked information resource: T-lymphocyte coactivator molecules.

Authorship 727848
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linked information resource: Harvard Catalyst | The Clinical Translational Science Center IND/IDE Consult Service: providing an IND/IDE consult service in a decentralized network of academic healthcare centers.

Harvard Catalyst | The Clinical Translational Science Center IND/IDE Consult Service: providing an IND/IDE consult service in a decentralized network of academic healthcare centers.
PubMed Identifier: 24455986
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Authorship 1795584
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Authorship 1812923
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Authorship 1827768
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Maintaining the Integrity of the Biomedical Research Record Through Timely, Appropriate Corrective Action.
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Practice of data sharing plans in clinical trial registrations and concordance between registered and published data sharing plans: a cross-sectional study.
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Disparate data retention standards in biomedical research.
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A scoping review of challenges in pediatric health technology assessments with a focus on pharmaceutical interventions.
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Characteristics of long-term follow-up studies for gene therapies registered on ClinicalTrials.gov.
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Ethical, Legal, and Social Issues (ELSI) in Human Somatic Gene Therapy Clinical Research: A Scoping Review.
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Disclosure of Pregnancy-Related Privacy Risks in Clinical Research Post-Dobbs.
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Parker B. Francis Distinguished Professor of Medicine
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Assistant Professor of Health Policy and Management
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Associate Professor of Pediatrics
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Authorship 750199
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linked information resource: Research misconduct involving noncompliance in human subjects research supported by the public health service: reconciling separate regulatory systems.

Authorship 751399
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linked information resource: A distributed model: redefining a robust research subject advocacy program at the Harvard Clinical and Translational Science Center.

Research misconduct involving noncompliance in human subjects research supported by the public health service: reconciling separate regulatory systems.
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author list: Bierer BE, Barnes M
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A distributed model: redefining a robust research subject advocacy program at the Harvard Clinical and Translational Science Center.
PubMed Identifier: 24841488
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linked information resource: Identification and characterization of an immunophilin expressed during the clonal expansion phase of adipocyte differentiation.

Authorship 376607
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linked information resource: Ex vivo rapamycin generates donor Th2 cells that potently inhibit graft-versus-host disease and graft-versus-tumor effects via an IL-4-dependent mechanism.

Authorship 361934
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linked information resource: Separable portions of the CD2 cytoplasmic domain involved in signaling and ligand avidity regulation.

Authorship 46901
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linked information resource: T3 glycoprotein is functional although structurally distinct on human T-cell receptor gamma T lymphocytes.

Authorship 499422
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linked information resource: Phorbol ester treatment inhibits phosphatidylinositol 3-kinase activation by, and association with, CD28, a T-lymphocyte surface receptor.

Authorship 53275
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linked information resource: Recombinant human interleukin-1 receptor antagonist in the treatment of steroid-resistant graft-versus-host disease.

Authorship 553274
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linked information resource: Activation-dependent phosphorylation of the T-lymphocyte surface receptor CD28 and associated proteins.

Authorship 301752
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linked information resource: Competitive inhibition of calcineurin phosphatase activity by its autoinhibitory domain.

Authorship 517144
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linked information resource: Biology of cyclosporin A and FK506.

Authorship 338834
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linked information resource: Expression and function of a CD5 cDNA in human and murine T cells.

Authorship 478053
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linked information resource: CD28 engagement promotes actin polymerization through the activation of the small Rho GTPase Cdc42 in human T cells.

Authorship 219474
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Authorship 359770
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linked information resource: Localization of the FK506-binding protein, FKBP 13, to the lumen of the endoplasmic reticulum.

Authorship 531983
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Authorship 229676
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linked information resource: T-lymphocyte activation: the biology and function of CD2 and CD4.

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Authorship 48268
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linked information resource: Selective depletion of bone marrow T lymphocytes with anti-CD5 monoclonal antibodies: effective prophylaxis for graft-versus-host disease in patients with hematologic malignancies.

Authorship 530317
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linked information resource: The interaction of CD2 with its LFA-3 ligand expressed by autologous erythrocytes results in enhancement of B cell responses.

Authorship 560155
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linked author: Bierer, Barbara
linked information resource: Suppression of human IL-1beta, IL-2, IFN-gamma, and TNF-alpha production by cigarette smoke extracts.

Authorship 298687
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linked information resource: Enhancement of T-cell activation by the CD43 molecule whose expression is defective in Wiskott-Aldrich syndrome.

Authorship 76277
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linked information resource: Expression of the T-cell surface molecule CD2 and an epitope-loss CD2 mutant to define the role of lymphocyte function-associated antigen 3 (LFA-3) in T-cell activation.

Authorship 29065
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linked information resource: CD43, a molecule defective in Wiskott-Aldrich syndrome, binds ICAM-1.

Authorship 334569
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linked information resource: Inhibition of calcineurin phosphatase activity in adult bone marrow transplant patients treated with cyclosporine A.

Authorship 26921
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linked information resource: Lateral mobility of class I histocompatibility antigens in B lymphoblastoid cell membranes: modulation by cross-linking and effect of cell density.

Authorship 359910
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linked information resource: Cloning and characterization of N4WBP5A, an inducible, cyclosporine-sensitive, Nedd4-binding protein in human T lymphocytes.

Authorship 210803
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linked information resource: Cross-linking CD28 leads to activation of 70-kDa S6 kinase.

Authorship 272653
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author rank in publication: 1
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linked information resource: T cell adhesion molecules.

Authorship 357856
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linked information resource: Rapamycin-induced inhibition of the 70-kilodalton S6 protein kinase.

Authorship 339907
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linked information resource: T cell signal transduction and the role of CD7 in costimulation.

Authorship 570558
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linked information resource: Signaling through CD28/CTLA-4 family receptors: puzzling participation of phosphatidylinositol-3 kinase.

Authorship 575602
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linked information resource: Regulation of CXCR4 expression in human T lymphocytes by calcium and calcineurin.

Authorship 273284
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linked information resource: Interaction of CD2 with its ligand, LFA-3, in human T cell proliferation.

Authorship 283028
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linked information resource: FK506 binding protein 12 mediates sensitivity to both FK506 and rapamycin in murine mast cells.

Authorship 346220
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linked author: Bierer, Barbara
linked information resource: Signaling via LAT (linker for T-cell activation) and Syk/ZAP70 is required for ERK activation and NFAT transcriptional activation following CD2 stimulation.

Authorship 144763
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linked information resource: Abnormal cytolytic activity of lymphocyte function-associated antigen-1-deficient human cytolytic T lymphocyte clones.

Authorship 148786
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linked information resource: Association of CD2 with tubulin. Evidence for a role of the cytoskeleton in T cell activation.

Authorship 264244
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linked information resource: Differential chemokine expression profiles in human peripheral blood T lymphocytes: dependence on T-cell coreceptor and calcineurin signaling.

Authorship 291947
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linked author: Bierer, Barbara
linked information resource: Overlapping but nonidentical binding sites on CD2 for CD58 and a second ligand CD59.

Authorship 404109
type: Authorship
author rank in publication: 1
linked author: Bierer, Barbara
linked information resource: Cyclosporin A, FK506, and rapamycin: binding to immunophilins and biological action.

Authorship 4329
type: Authorship
author rank in publication: 1
linked author: Bierer, Barbara
linked information resource: Regulation of cytotoxic T lymphocyte-mediated graft rejection following bone marrow transplantation.

Authorship 52526
type: Authorship
author rank in publication: 2
linked author: Bierer, Barbara
linked information resource: The complex of FK506-binding protein 12 and FK506 inhibits calcineurin phosphatase activity and IgE activation-induced cytokine transcripts, but not exocytosis, in mouse mast cells.

Authorship 547049
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author rank in publication: 2
linked author: Bierer, Barbara
linked information resource: Actin stabilization by jasplakinolide enhances apoptosis induced by cytokine deprivation.

Authorship 156720
type: Authorship
author rank in publication: 2
linked author: Bierer, Barbara
linked information resource: Prevention and treatment of sickle cell crisis by induced hyponatremia.

Authorship 418990
type: Authorship
author rank in publication: 6
linked author: Bierer, Barbara
linked information resource: Up-regulation of HIV coreceptor CXCR4 expression in human T lymphocytes is mediated in part by a cAMP-responsive element.

Authorship 788950
type: Authorship
author rank in publication: 3
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linked information resource: Compliance with results reporting at ClinicalTrials.gov.

Authorship 787039
type: Authorship
author rank in publication: 3
linked author: Bierer, Barbara
linked information resource: The Harvard Catalyst Common Reciprocal IRB Reliance Agreement: an innovative approach to multisite IRB review and oversight.

The Harvard Catalyst Common Reciprocal IRB Reliance Agreement: an innovative approach to multisite IRB review and oversight.
PubMed Identifier: 25196592
author list: Winkler SJ, Witte E, Bierer BE
published in: Clinical and translational science
information resource reference: The Harvard Catalyst Common Reciprocal IRB Reliance Agreement: an innovative approach to multisite IRB review and oversight. Clin Transl Sci. 2015 Feb; 8(1):57-66.
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publication date: 2014-09-08T00:00:00
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type: Academic Article
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Compliance with results reporting at ClinicalTrials.gov.
PubMed Identifier: 26061854
author list: Hallinan ZP, Getz KA, Bierer BE
published in: The New England journal of medicine
information resource reference: Compliance with results reporting at ClinicalTrials.gov. N Engl J Med. 2015 06 11; 372(24):2370.
journal title abbreviation: N Engl J Med
publication date: 2015-06-11T00:00:00
year: 2015
type: Academic Article
type: Article
type: Document
type: Information Resource

Informatics
type: Division
type: Organization

Authorship 74660
type: Authorship
author rank in publication: 2
linked author: Bierer, Barbara
linked information resource: Analysis of CD4 and CD2 receptor function.

Authorship 548034
type: Authorship
author rank in publication: 3
linked author: Bierer, Barbara
linked information resource: Signal transduction pathways involved in T cell receptor-induced regulation of CD2 avidity for CD58.

Authorship 375284
type: Authorship
author rank in publication: 4
linked author: Bierer, Barbara
linked information resource: Calcium- and FK506-independent interaction between the immunophilin FKBP51 and calcineurin.

Authorship 28880
type: Authorship
author rank in publication: 1
linked author: Bierer, Barbara
linked information resource: T cell receptors: adhesion and signaling.

Authorship 283210
type: Authorship
author rank in publication: 5
linked author: Bierer, Barbara
linked information resource: The APC-associated protein EB1 associates with components of the dynactin complex and cytoplasmic dynein intermediate chain.

Authorship 288559
type: Authorship
author rank in publication: 5
linked author: Bierer, Barbara
linked information resource: Expression of human interleukin-3 (multi-CSF) is restricted to human lymphocytes and T-cell tumor lines.

Authorship 29314
type: Authorship
author rank in publication: 1
linked author: Bierer, Barbara
linked information resource: Partial deletions of the cytoplasmic domain of CD2 result in a partial defect in signal transduction.

Authorship 356343
type: Authorship
author rank in publication: 3
linked author: Bierer, Barbara
linked information resource: Disruption of T cell development and repertoire selection by calcineurin inhibition in vivo.

Authorship 359855
type: Authorship
author rank in publication: 6
linked author: Bierer, Barbara
linked information resource: Gelsolin overexpression alters actin dynamics and tyrosine phosphorylation of lipid raft-associated proteins in Jurkat T cells.

Authorship 360567
type: Authorship
author rank in publication: 3
linked author: Bierer, Barbara
linked information resource: Differential phosphorylation of the T lymphocyte costimulatory receptor CD28. Activation-dependent changes and regulation by protein kinase C.

Authorship 369656
type: Authorship
author rank in publication: 3
linked author: Bierer, Barbara
linked information resource: Calcineurin phosphatase activity in T lymphocytes is inhibited by FK 506 and cyclosporin A.

Authorship 527243
type: Authorship
author rank in publication: 4
linked author: Bierer, Barbara
linked information resource: Molecular cloning of a membrane-associated human FK506- and rapamycin-binding protein, FKBP-13.

Authorship 399438
type: Authorship
author rank in publication: 1
linked author: Bierer, Barbara
linked information resource: The effect of the immunosuppressant FK-506 on alternate pathways of T cell activation.

Authorship 848103
type: Authorship
author rank in publication: 3
linked author: Bierer, Barbara
linked information resource: The Education Review Board: A Mechanism for Managing Potential Conflicts of Interest in Medical Education.

The Education Review Board: A Mechanism for Managing Potential Conflicts of Interest in Medical Education.
PubMed Identifier: 26083402
author list: Borus JF, Alexander EK, Bierer BE, Bringhurst FR, Clark C, Klanica KE, Stewart EC, Friedman LS
published in: Academic medicine : journal of the Association of American Medical Colleges
information resource reference: The Education Review Board: A Mechanism for Managing Potential Conflicts of Interest in Medical Education. Acad Med. 2015 Dec; 90(12):1611-7.
journal title abbreviation: Acad Med
publication date: 2015-12-01T00:00:00
year: 2015
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 467469
type: Authorship
author rank in publication: 2
linked author: Bierer, Barbara
linked information resource: Rapamycin inhibits clonal expansion and adipogenic differentiation of 3T3-L1 cells.

Authorship 486068
type: Authorship
author rank in publication: 5
linked author: Bierer, Barbara
linked information resource: Differences between CEM and human peripheral blood T lymphocytes in cAMP-dependent HIV viral fusion and CXCR4 expression.

Authorship 51711
type: Authorship
author rank in publication: 10
linked author: Bierer, Barbara
linked information resource: Enhancing safety reporting in adult ambulatory oncology with a clinician champion: a practice innovation.

Authorship 858471
type: Authorship
author rank in publication: 2
linked author: Bierer, Barbara
linked information resource: Confronting Biospecimen Exceptionalism in Proposed Revisions to the Common Rule.

Confronting Biospecimen Exceptionalism in Proposed Revisions to the Common Rule.
PubMed Identifier: 26786034
author list: Lynch HF, Bierer BE, Cohen IG
published in: The Hastings Center report
information resource reference: Confronting Biospecimen Exceptionalism in Proposed Revisions to the Common Rule. Hastings Cent Rep. 2016 Jan-Feb; 46(1):4-5.
journal title abbreviation: Hastings Cent Rep
publication date: 2016-01-01T00:00:00
year: 2016
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 866643
type: Authorship
author rank in publication: 2
linked author: Bierer, Barbara
linked information resource: Standards for Clinical Research: Keeping Pace With the Technology of the Future.

Authorship 93805
type: Authorship
author rank in publication: 2
linked author: Bierer, Barbara
linked information resource: Expression of CD5 regulates responsiveness to IL-1.

Standards for Clinical Research: Keeping Pace With the Technology of the Future.
PubMed Identifier: 26927004
author list: Antman EM, Bierer BE
published in: Circulation
information resource reference: Standards for Clinical Research: Keeping Pace With the Technology of the Future. Circulation. 2016 Mar 01; 133(9):823-5.
journal title abbreviation: Circulation
publication date: 2016-03-01T00:00:00
year: 2016
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 68059
type: Authorship
author rank in publication: 1
linked author: Bierer, Barbara
linked information resource: Probing immunosuppressant action with a nonnatural immunophilin ligand.

Authorship 872950
type: Authorship
author rank in publication: 20
linked author: Bierer, Barbara
linked information resource: Incorporating ethical principles into clinical research protocols: a tool for protocol writers and ethics committees.

Incorporating ethical principles into clinical research protocols: a tool for protocol writers and ethics committees.
PubMed Identifier: 26811365
author list: Li RH, Wacholtz MC, Barnes M, Boggs L, Callery-D'Amico S, Davis A, Digilova A, Forster D, Heffernan K, Luthin M, Lynch HF, McNair L, Miller JE, Murphy J, Van Campen L, Wilenzick M, Wolf D, Woolston C, Aldinger C, Bierer BE
published in: Journal of medical ethics
information resource reference: Incorporating ethical principles into clinical research protocols: a tool for protocol writers and ethics committees. J Med Ethics. 2016 Apr; 42(4):229-34.
journal title abbreviation: J Med Ethics
publication date: 2016-01-25T00:00:00
year: 2016
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 444988
type: Authorship
author rank in publication: 3
linked author: Bierer, Barbara
linked information resource: Q-T prolongation and torsades de pointes ventricular tachycardia produced by the tetracyclic antidepressant agent maprotiline.

Authorship 464127
type: Authorship
author rank in publication: 5
linked author: Bierer, Barbara
linked information resource: Characterization of HTLV-I in vivo infected T cell clones. IL-2-independent growth of nontransformed T cells.

Authorship 82268
type: Authorship
author rank in publication: 1
linked author: Bierer, Barbara
linked information resource: Cyclosporin A and FK506: molecular mechanisms of immunosuppression and probes for transplantation biology.

Authorship 888253
type: Authorship
author rank in publication: 1
linked author: Bierer, Barbara
linked information resource: A Global, Neutral Platform for Sharing Trial Data.

A Global, Neutral Platform for Sharing Trial Data.
PubMed Identifier: 27168194
author list: Bierer BE, Li R, Barnes M, Sim I
published in: The New England journal of medicine
information resource reference: A Global, Neutral Platform for Sharing Trial Data. N Engl J Med. 2016 Jun 23; 374(25):2411-3.
journal title abbreviation: N Engl J Med
publication date: 2016-05-11T00:00:00
year: 2016
type: Academic Article
type: Article
type: Document
type: Information Resource

Assistant Professor
sort order: 2
type: Faculty Rank

Associate Professor
sort order: 1
type: Faculty Rank

Fellow or Post Doc
sort order: 6
type: Faculty Rank

Full Professor
sort order: 0
type: Faculty Rank

Instructor
sort order: 4
type: Faculty Rank

Authorship 94554
type: Authorship
author rank in publication: 1
linked author: Bierer, Barbara
linked information resource: Synergistic T cell activation via the physiological ligands for CD2 and the T cell receptor.

Authorship 94201
type: Authorship
author rank in publication: 4
linked author: Bierer, Barbara
linked information resource: Yeast Bim1p promotes the G1-specific dynamics of microtubules.

MECHANISMS OF IMMUNOSUPPRESSION BY FK506
end date: 1997-12-31
principal investigator name: BIERER, BARBARA E
start date: 1993-01-01
type: Grant
sponsor award id: R01AI032514

Short-Term Research Education Program to Increase Diversity in Health-Related Res
end date: 2018-02-28
principal investigator name: LEWIS, ELDRIN F
start date: 2012-08-01
type: Grant
sponsor award id: R25HL115510

General Clinical Research Center
end date: 2010-03-31
principal investigator name: GOTTLIEB, GARY L
start date: 1984-12-01
type: Grant
sponsor award id: M01RR002635

CD2 AND T-CELL ADHESION AND ACTIVATION
end date: 1999-06-30
principal investigator name: BIERER, BARBARA E
start date: 1989-07-01
type: Grant
sponsor award id: R01AI028554

Immune Tolerance and Autoimmunity
end date: 2012-07-31
principal investigator name: ABBAS, ABUL K.
start date: 1993-09-30
type: Grant
sponsor award id: P01AI035297

Cellular and Molecular Studies of Bone Marrow Transplant
end date: 2021-08-31
principal investigator name: FERRARA, JAMES L. M.
start date: 1985-09-30
type: Grant
sponsor award id: P01CA039542

Centers For Clinical Research on TransplantaTION
end date: 2001-09-30
principal investigator name: GUINAN, EVA C
start date: 1996-09-30
type: Grant
sponsor award id: N01HB067133

INTERACTION OF CD-2 WITH LFA-3 IN T CELL ACTIVATION
end date: 1994-06-30
principal investigator name: BIERER, BARBARA E
start date: 1989-07-01
type: Grant
sponsor award id: R29AI028554

Short-Term Training in Cardiovascular Research
end date: 2015-03-31
principal investigator name: BIERER, BARBARA E
start date: 2009-04-01
type: Grant
sponsor award id: R25HL096364

Principal Investigator
type: Researcher Role
researcher role of: Bierer, Barbara
contributes to: Short-Term Research Education Program to Increase Diversity in Health-Related Res

Principal Investigator
type: Researcher Role
researcher role of: Bierer, Barbara
contributes to: CD2 AND T-CELL ADHESION AND ACTIVATION

Principal Investigator
type: Researcher Role
researcher role of: Bierer, Barbara
contributes to: MECHANISMS OF IMMUNOSUPPRESSION BY FK506

Co-Principal Investigator
type: Researcher Role
researcher role of: Bierer, Barbara
contributes to: Immune Tolerance and Autoimmunity

Co-Principal Investigator
type: Researcher Role
researcher role of: Bierer, Barbara
contributes to: Cellular and Molecular Studies of Bone Marrow Transplant

Principal Investigator
type: Researcher Role
researcher role of: Bierer, Barbara
contributes to: Short-Term Training in Cardiovascular Research

Co-Principal Investigator
type: Researcher Role
researcher role of: Bierer, Barbara
contributes to: General Clinical Research Center

Principal Investigator
type: Researcher Role
researcher role of: Bierer, Barbara
contributes to: INTERACTION OF CD-2 WITH LFA-3 IN T CELL ACTIVATION

Co-Principal Investigator
type: Researcher Role
researcher role of: Bierer, Barbara
contributes to: Centers For Clinical Research on TransplantaTION

Authorship 3731
type: Authorship
author rank in publication: 3
linked author: Bierer, Barbara
linked information resource: Molecular cloning of a 25-kDa high affinity rapamycin binding protein, FKBP25.

Authorship 202754
type: Authorship
author rank in publication: 5
linked author: Bierer, Barbara
linked information resource: A distinct cytoplasmic domain of CD2 regulates ligand avidity and T-cell responsiveness to antigen.

Authorship 273237
type: Authorship
author rank in publication: 4
linked author: Bierer, Barbara
linked information resource: Sialophorin, a surface sialoglycoprotein defective in the Wiskott-Aldrich syndrome, is involved in human T lymphocyte proliferation.

Authorship 543200
type: Authorship
author rank in publication: 1
linked author: Bierer, Barbara
linked information resource: A large proportion of T lymphocytes lack CD5 expression after bone marrow transplantation.

Competitive inhibition of calcineurin phosphatase activity by its autoinhibitory domain.
PubMed Identifier: 9003375
author list: Sagoo JK, Fruman DA, Wesselborg S, Walsh CT, Bierer BE
published in: The Biochemical journal
information resource reference: Competitive inhibition of calcineurin phosphatase activity by its autoinhibitory domain. Biochem J. 1996 Dec 15; 320 ( Pt 3):879-84.
journal title abbreviation: Biochem J
publication date: 1996-12-15T00:00:00
year: 1996
type: Academic Article
type: Article
type: Document
type: Information Resource

Interleukin 2 stimulation of p70 S6 kinase activity is inhibited by the immunosuppressant rapamycin.
PubMed Identifier: 1380162
author list: Calvo V, Crews CM, Vik TA, Bierer BE
published in: Proceedings of the National Academy of Sciences of the United States of America
information resource reference: Interleukin 2 stimulation of p70 S6 kinase activity is inhibited by the immunosuppressant rapamycin. Proc Natl Acad Sci U S A. 1992 Aug 15; 89(16):7571-5.
journal title abbreviation: Proc Natl Acad Sci U S A
publication date: 1992-08-15T00:00:00
year: 1992
type: Academic Article
type: Article
type: Document
type: Information Resource

Calcium- and FK506-independent interaction between the immunophilin FKBP51 and calcineurin.
PubMed Identifier: 11813252
author list: Li TK, Baksh S, Cristillo AD, Bierer BE
published in: Journal of cellular biochemistry
information resource reference: Calcium- and FK506-independent interaction between the immunophilin FKBP51 and calcineurin. J Cell Biochem. 2002; 84(3):460-71.
journal title abbreviation: J Cell Biochem
publication date: 2002-01-01T00:00:00
year: 2002
type: Academic Article
type: Article
type: Document
type: Information Resource

Isolated testicular relapse in an adolescent 5 years following allogeneic bone marrow transplantation for acute myelogenous leukemia.
PubMed Identifier: 9134181
author list: Lehmann LE, Guinan EC, Halpern SL, Donovan MJ, Bierer BE, Parsons SK
published in: Bone marrow transplantation
information resource reference: Isolated testicular relapse in an adolescent 5 years following allogeneic bone marrow transplantation for acute myelogenous leukemia. Bone Marrow Transplant. 1997 Apr; 19(8):849-51.
journal title abbreviation: Bone Marrow Transplant
publication date: 1997-04-01T00:00:00
year: 1997
type: Academic Article
type: Article
type: Document
type: Information Resource

Correlation of calcineurin phosphatase activity and programmed cell death in murine T cell hybridomas.
PubMed Identifier: 1382988
author list: Fruman DA, Mather PE, Burakoff SJ, Bierer BE
published in: European journal of immunology
information resource reference: Correlation of calcineurin phosphatase activity and programmed cell death in murine T cell hybridomas. Eur J Immunol. 1992 Oct; 22(10):2513-7.
journal title abbreviation: Eur J Immunol
publication date: 1992-10-01T00:00:00
year: 1992
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 966493
type: Authorship
author rank in publication: 3
linked author: Bierer, Barbara
linked information resource: When clinical trials compete: prioritising study recruitment.

When clinical trials compete: prioritising study recruitment.
PubMed Identifier: 28108613
author list: Gelinas L, Lynch HF, Bierer BE, Cohen IG
published in: Journal of medical ethics
information resource reference: When clinical trials compete: prioritising study recruitment. J Med Ethics. 2017 12; 43(12):803-809.
journal title abbreviation: J Med Ethics
publication date: 2017-01-20T00:00:00
year: 2017
type: Academic Article
type: Article
type: Document
type: Information Resource

A distinct cytoplasmic domain of CD2 regulates ligand avidity and T-cell responsiveness to antigen.
PubMed Identifier: 1353888
author list: Hahn WC, Rosenstein Y, Calvo V, Burakoff SJ, Bierer BE
published in: Proceedings of the National Academy of Sciences of the United States of America
information resource reference: A distinct cytoplasmic domain of CD2 regulates ligand avidity and T-cell responsiveness to antigen. Proc Natl Acad Sci U S A. 1992 Aug 01; 89(15):7179-83.
journal title abbreviation: Proc Natl Acad Sci U S A
publication date: 1992-08-01T00:00:00
year: 1992
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 967279
type: Authorship
author rank in publication: 6
linked author: Bierer, Barbara
linked information resource: Using Social Media as a Research Recruitment Tool: Ethical Issues and Recommendations.

Using Social Media as a Research Recruitment Tool: Ethical Issues and Recommendations.
PubMed Identifier: 28207365
author list: Gelinas L, Pierce R, Winkler S, Cohen IG, Lynch HF, Bierer BE
published in: The American journal of bioethics : AJOB
information resource reference: Using Social Media as a Research Recruitment Tool: Ethical Issues and Recommendations. Am J Bioeth. 2017 Mar; 17(3):3-14.
journal title abbreviation: Am J Bioeth
publication date: 2017-03-01T00:00:00
year: 2017
type: Academic Article
type: Article
type: Document
type: Information Resource

Suppression of human IL-1beta, IL-2, IFN-gamma, and TNF-alpha production by cigarette smoke extracts.
PubMed Identifier: 10932071
author list: Ouyang Y, Virasch N, Hao P, Aubrey MT, Mukerjee N, Bierer BE, Freed BM
published in: The Journal of allergy and clinical immunology
information resource reference: Suppression of human IL-1beta, IL-2, IFN-gamma, and TNF-alpha production by cigarette smoke extracts. J Allergy Clin Immunol. 2000 Aug; 106(2):280-7.
journal title abbreviation: J Allergy Clin Immunol
publication date: 2000-08-01T00:00:00
year: 2000
type: Academic Article
type: Article
type: Document
type: Information Resource

T cell receptors: adhesion and signaling.
PubMed Identifier: 2028842
author list: Bierer BE, Burakoff SJ
published in: Advances in cancer research
information resource reference: T cell receptors: adhesion and signaling. Adv Cancer Res. 1991; 56:49-76.
journal title abbreviation: Adv Cancer Res
publication date: 1991-01-01T00:00:00
year: 1991
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 972965
type: Authorship
author rank in publication: 16
linked author: Bierer, Barbara
linked information resource: Building Workforce Capacity Abroad While Strengthening Global Health Programs at Home: Participation of Seven Harvard-Affiliated Institutions in a Health Professional Training Initiative in Rwanda.

Building Workforce Capacity Abroad While Strengthening Global Health Programs at Home: Participation of Seven Harvard-Affiliated Institutions in a Health Professional Training Initiative in Rwanda.
PubMed Identifier: 28328735
author list: Cancedda C, Riviello R, Wilson K, Scott KW, Tuteja M, Barrow JR, Hedt-Gauthier B, Bukhman G, Scott J, Milner D, Raviola G, Weissman B, Smith S, Nuthulaganti T, McClain CD, Bierer BE, Farmer PE, Becker AE, Binagwaho A, Rhatigan J, Golan DE
published in: Academic medicine : journal of the Association of American Medical Colleges
information resource reference: Building Workforce Capacity Abroad While Strengthening Global Health Programs at Home: Participation of Seven Harvard-Affiliated Institutions in a Health Professional Training Initiative in Rwanda. Acad Med. 2017 05; 92(5):649-658.
journal title abbreviation: Acad Med
publication date: 2017-05-01T00:00:00
year: 2017
type: Academic Article
type: Article
type: Document
type: Information Resource

Depletion of bone marrow T-lymphocytes with an anti-CD5 monoclonal immunotoxin (ST-1 immunotoxin): effective prophylaxis for graft-versus-host disease.
PubMed Identifier: 1689852
author list: Antin JH, Bierer BE, Smith BR, Guinan EC, Provost MM, Ferrara J, Macklis RM, Tarbell NJ, Blythman H, Bouloux C
published in: Progress in clinical and biological research
information resource reference: Depletion of bone marrow T-lymphocytes with an anti-CD5 monoclonal immunotoxin (ST-1 immunotoxin): effective prophylaxis for graft-versus-host disease. Prog Clin Biol Res. 1990; 333:207-15.
journal title abbreviation: Prog Clin Biol Res
publication date: 1990-01-01T00:00:00
year: 1990
type: Academic Article
type: Article
type: Document
type: Information Resource

Identification of a proline-rich sequence in the CD2 cytoplasmic domain critical for regulation of integrin-mediated adhesion and activation of phosphoinositide 3-kinase.
PubMed Identifier: 9710614
author list: Kivens WJ, Hunt SW, Mobley JL, Zell T, Dell CL, Bierer BE, Shimizu Y
published in: Molecular and cellular biology
information resource reference: Identification of a proline-rich sequence in the CD2 cytoplasmic domain critical for regulation of integrin-mediated adhesion and activation of phosphoinositide 3-kinase. Mol Cell Biol. 1998 Sep; 18(9):5291-307.
journal title abbreviation: Mol Cell Biol
publication date: 1998-09-01T00:00:00
year: 1998
type: Academic Article
type: Article
type: Document
type: Information Resource

Molecular cloning of a membrane-associated human FK506- and rapamycin-binding protein, FKBP-13.
PubMed Identifier: 1713687
author list: Jin YJ, Albers MW, Lane WS, Bierer BE, Schreiber SL, Burakoff SJ
published in: Proceedings of the National Academy of Sciences of the United States of America
information resource reference: Molecular cloning of a membrane-associated human FK506- and rapamycin-binding protein, FKBP-13. Proc Natl Acad Sci U S A. 1991 Aug 01; 88(15):6677-81.
journal title abbreviation: Proc Natl Acad Sci U S A
publication date: 1991-08-01T00:00:00
year: 1991
type: Academic Article
type: Article
type: Document
type: Information Resource

FK 506 and rapamycin: molecular probes of T-lymphocyte activation.
PubMed Identifier: 1721296
author list: Bierer BE, Jin YJ, Fruman DA, Calvo V, Burakoff SJ
published in: Transplantation proceedings
information resource reference: FK 506 and rapamycin: molecular probes of T-lymphocyte activation. Transplant Proc. 1991 Dec; 23(6):2850-5.
journal title abbreviation: Transplant Proc
publication date: 1991-12-01T00:00:00
year: 1991
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 975242
type: Authorship
author rank in publication: 3
linked author: Bierer, Barbara
linked information resource: Institutions as an ethical locus of research prioritisation.

Institutions as an ethical locus of research prioritisation.
PubMed Identifier: 28385733
author list: Gelinas L, Lynch HF, Bierer B, Cohen IG
published in: Journal of medical ethics
information resource reference: Institutions as an ethical locus of research prioritisation. J Med Ethics. 2017 12; 43(12):816-818.
journal title abbreviation: J Med Ethics
publication date: 2017-04-06T00:00:00
year: 2017
type: Academic Article
type: Article
type: Document
type: Information Resource

Gelsolin overexpression alters actin dynamics and tyrosine phosphorylation of lipid raft-associated proteins in Jurkat T cells.
PubMed Identifier: 17178161
author list: Morley SC, Sung J, Sun GP, Martelli MP, Bunnell SC, Bierer BE
published in: Molecular immunology
information resource reference: Gelsolin overexpression alters actin dynamics and tyrosine phosphorylation of lipid raft-associated proteins in Jurkat T cells. Mol Immunol. 2007 Mar; 44(9):2469-80.
journal title abbreviation: Mol Immunol
publication date: 2006-12-18T00:00:00
year: 2006
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 977011
type: Authorship
author rank in publication: 1
linked author: Bierer, Barbara
linked information resource: Data Authorship as an Incentive to Data Sharing.

Data Authorship as an Incentive to Data Sharing.
PubMed Identifier: 28402238
author list: Bierer BE, Crosas M, Pierce HH
published in: The New England journal of medicine
information resource reference: Data Authorship as an Incentive to Data Sharing. N Engl J Med. 2017 04 27; 376(17):1684-1687.
journal title abbreviation: N Engl J Med
publication date: 2017-03-29T00:00:00
year: 2017
type: Academic Article
type: Article
type: Document
type: Information Resource

https://connects.catalyst.harvard.edu/Profiles/profile/783405
PubMed Identifier: 9414288
author list: Dunussi-Joannopoulos K, Dranoff G, Weinstein HJ, Ferrara JL, Bierer BE, Croop JM
published in: Blood
information resource reference: Gene immunotherapy in murine acute myeloid leukemia: granulocyte-macrophage colony-stimulating factor tumor cell vaccines elicit more potent antitumor immunity compared with B7 family and other cytokine vaccines. Blood. 1998 Jan 01; 91(1):222-30.
journal title abbreviation: Blood
publication date: 1998-01-01T00:00:00
year: 1998
type: Academic Article
type: Article
type: Document
type: Information Resource
label: Gene immunotherapy in murine acute myeloid leukemia: granulocyte-macrophage colony-stimulating factor tumor cell vaccines elicit more potent antitumor immunity compared with B7 family and other cytokine vaccines.

Differences between CEM and human peripheral blood T lymphocytes in cAMP-dependent HIV viral fusion and CXCR4 expression.
PubMed Identifier: 12127049
author list: Cristillo AD, Xiao X, Campbell-Malone R, Dimitrov DS, Bierer BE
published in: Experimental and molecular pathology
information resource reference: Differences between CEM and human peripheral blood T lymphocytes in cAMP-dependent HIV viral fusion and CXCR4 expression. Exp Mol Pathol. 2002 Aug; 73(1):9-18.
journal title abbreviation: Exp Mol Pathol
publication date: 2002-08-01T00:00:00
year: 2002
type: Academic Article
type: Article
type: Document
type: Information Resource

Signaling via LAT (linker for T-cell activation) and Syk/ZAP70 is required for ERK activation and NFAT transcriptional activation following CD2 stimulation.
PubMed Identifier: 10979964
author list: Martelli MP, Lin H, Zhang W, Samelson LE, Bierer BE
published in: Blood
information resource reference: Signaling via LAT (linker for T-cell activation) and Syk/ZAP70 is required for ERK activation and NFAT transcriptional activation following CD2 stimulation. Blood. 2000 Sep 15; 96(6):2181-90.
journal title abbreviation: Blood
publication date: 2000-09-15T00:00:00
year: 2000
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 977983
type: Authorship
author rank in publication: 6
linked author: Bierer, Barbara
linked information resource: Nonexceptionalism, Research Risks, and Social Media: Response to Open Peer Commentaries on "Using Social Media as a Research Recruitment Tool: Ethical Issues and Recommendations".

Nonexceptionalism, Research Risks, and Social Media: Response to Open Peer Commentaries on "Using Social Media as a Research Recruitment Tool: Ethical Issues and Recommendations".
PubMed Identifier: 28430072
author list: Gelinas L, Pierce R, Winkler S, Cohen G, Lynch HF, Bierer BE
published in: The American journal of bioethics : AJOB
information resource reference: Nonexceptionalism, Research Risks, and Social Media: Response to Open Peer Commentaries on "Using Social Media as a Research Recruitment Tool: Ethical Issues and Recommendations". Am J Bioeth. 2017 05; 17(5):W1-W3.
journal title abbreviation: Am J Bioeth
publication date: 2017-05-01T00:00:00
year: 2017
type: Academic Article
type: Article
type: Document
type: Information Resource

Tacrolimus (FK506) in allogeneic bone marrow transplantation for severe aplastic anemia following orthotopic liver transplantation.
PubMed Identifier: 9257897
author list: Trede NS, Warwick AB, Rosoff PM, Rohrer R, Bierer BE, Guinan E
published in: Bone marrow transplantation
information resource reference: Tacrolimus (FK506) in allogeneic bone marrow transplantation for severe aplastic anemia following orthotopic liver transplantation. Bone Marrow Transplant. 1997 Aug; 20(3):257-60.
journal title abbreviation: Bone Marrow Transplant
publication date: 1997-08-01T00:00:00
year: 1997
type: Academic Article
type: Article
type: Document
type: Information Resource

Bone marrow transplantation for therapy-related myelodysplasia: comparison with primary myelodysplasia.
PubMed Identifier: 9384475
author list: Ballen KK, Gilliland DG, Guinan EC, Hsieh CC, Parsons SK, Rimm IJ, Ferrara JL, Bierer BE, Weinstein HJ, Antin JH
published in: Bone marrow transplantation
information resource reference: Bone marrow transplantation for therapy-related myelodysplasia: comparison with primary myelodysplasia. Bone Marrow Transplant. 1997 Nov; 20(9):737-43.
journal title abbreviation: Bone Marrow Transplant
publication date: 1997-11-01T00:00:00
year: 1997
type: Academic Article
type: Article
type: Document
type: Information Resource

T cell regulation of p62(dok) (Dok1) association with Crk-L.
PubMed Identifier: 11553620
author list: Martelli MP, Boomer J, Bu M, Bierer BE
published in: The Journal of biological chemistry
information resource reference: T cell regulation of p62(dok) (Dok1) association with Crk-L. J Biol Chem. 2001 Dec 07; 276(49):45654-61.
journal title abbreviation: J Biol Chem
publication date: 2001-09-11T00:00:00
year: 2001
type: Academic Article
type: Article
type: Document
type: Information Resource

Interaction of CD2 with its ligand lymphocyte function-associated antigen-3 induces adenosine 3',5'-cyclic monophosphate production in T lymphocytes.
PubMed Identifier: 1711070
author list: Hahn WC, Rosenstein Y, Burakoff SJ, Bierer BE
published in: Journal of immunology (Baltimore, Md. : 1950)
information resource reference: Interaction of CD2 with its ligand lymphocyte function-associated antigen-3 induces adenosine 3',5'-cyclic monophosphate production in T lymphocytes. J Immunol. 1991 Jul 01; 147(1):14-21.
journal title abbreviation: J Immunol
publication date: 1991-07-01T00:00:00
year: 1991
type: Academic Article
type: Article
type: Document
type: Information Resource

Cloning and characterization of N4WBP5A, an inducible, cyclosporine-sensitive, Nedd4-binding protein in human T lymphocytes.
PubMed Identifier: 12796489
author list: Cristillo AD, Nie L, Macri MJ, Bierer BE
published in: The Journal of biological chemistry
information resource reference: Cloning and characterization of N4WBP5A, an inducible, cyclosporine-sensitive, Nedd4-binding protein in human T lymphocytes. J Biol Chem. 2003 Sep 05; 278(36):34587-97.
journal title abbreviation: J Biol Chem
publication date: 2003-06-09T00:00:00
year: 2003
type: Academic Article
type: Article
type: Document
type: Information Resource

Failure of gelsolin overexpression to regulate lymphocyte apoptosis.
PubMed Identifier: 10828033
author list: Posey SC, Martelli MP, Azuma T, Kwiatkowski DJ, Bierer BE
published in: Blood
information resource reference: Failure of gelsolin overexpression to regulate lymphocyte apoptosis. Blood. 2000 Jun 01; 95(11):3483-8.
journal title abbreviation: Blood
publication date: 2000-06-01T00:00:00
year: 2000
type: Academic Article
type: Article
type: Document
type: Information Resource

The involvement of the proto-oncogene p120 c-Cbl and ZAP-70 in CD2-mediated T cell activation.
PubMed Identifier: 11133830
author list: Lin H, Martelli MP, Bierer BE
published in: International immunology
information resource reference: The involvement of the proto-oncogene p120 c-Cbl and ZAP-70 in CD2-mediated T cell activation. Int Immunol. 2001 Jan; 13(1):13-22.
journal title abbreviation: Int Immunol
publication date: 2001-01-01T00:00:00
year: 2001
type: Academic Article
type: Article
type: Document
type: Information Resource

T cell signal transduction and the role of CD7 in costimulation.
PubMed Identifier: 11485208
author list: Stillwell R, Bierer BE
published in: Immunologic research
information resource reference: T cell signal transduction and the role of CD7 in costimulation. Immunol Res. 2001; 24(1):31-52.
journal title abbreviation: Immunol Res
publication date: 2001-01-01T00:00:00
year: 2001
type: Academic Article
type: Article
type: Document
type: Information Resource

https://connects.catalyst.harvard.edu/Profiles/profile/807973
PubMed Identifier: 11509937
author list: Winston DJ, Antin JH, Wolff SN, Bierer BE, Small T, Miller KB, Linker C, Kaizer H, Lazarus HM, Petersen FB, Cowan MJ, Ho WG, Wingard JR, Schiller GJ, Territo MC, Jiao J, Petrarca MA, Tonetta SA
published in: Bone marrow transplantation
information resource reference: A multicenter, randomized, double-blind comparison of different doses of intravenous immunoglobulin for prevention of graft-versus-host disease and infection after allogeneic bone marrow transplantation. Bone Marrow Transplant. 2001 Jul; 28(2):187-96.
journal title abbreviation: Bone Marrow Transplant
publication date: 2001-07-01T00:00:00
year: 2001
type: Academic Article
type: Article
type: Document
type: Information Resource
label: A multicenter, randomized, double-blind comparison of different doses of intravenous immunoglobulin for prevention of graft-versus-host disease and infection after allogeneic bone marrow transplantation.

Up-regulation of HIV coreceptor CXCR4 expression in human T lymphocytes is mediated in part by a cAMP-responsive element.
PubMed Identifier: 11874984
author list: Cristillo AD, Highbarger HC, Dewar RL, Dimitrov DS, Golding H, Bierer BE
published in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology
information resource reference: Up-regulation of HIV coreceptor CXCR4 expression in human T lymphocytes is mediated in part by a cAMP-responsive element. FASEB J. 2002 Mar; 16(3):354-64.
journal title abbreviation: FASEB J
publication date: 2002-03-01T00:00:00
year: 2002
type: Academic Article
type: Article
type: Document
type: Information Resource

High-dose cyclophosphamide, carmustine, and etoposide with autologous transplantation in Hodgkin's disease: a prognostic model for treatment outcomes.
PubMed Identifier: 9267670
author list: Wheeler C, Eickhoff C, Elias A, Ibrahim J, Ayash L, McCauley M, Mauch P, Schwartz G, Eder JP, Mazanet R, Ferrara J, Rimm IJ, Guinan E, Bierer B, Gilliland G, Churchill WH, Ault K, Parsons S, Antman K, Schnipper L, Tepler I, Gaynes L, Frei E, Kadin M, Antin J
published in: Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation
information resource reference: High-dose cyclophosphamide, carmustine, and etoposide with autologous transplantation in Hodgkin's disease: a prognostic model for treatment outcomes. Biol Blood Marrow Transplant. 1997 Jun; 3(2):98-106.
journal title abbreviation: Biol Blood Marrow Transplant
publication date: 1997-06-01T00:00:00
year: 1997
type: Academic Article
type: Article
type: Document
type: Information Resource

Molecular cloning of a 25-kDa high affinity rapamycin binding protein, FKBP25.
PubMed Identifier: 1375932
author list: Jin YJ, Burakoff SJ, Bierer BE
published in: The Journal of biological chemistry
information resource reference: Molecular cloning of a 25-kDa high affinity rapamycin binding protein, FKBP25. J Biol Chem. 1992 Jun 05; 267(16):10942-5.
journal title abbreviation: J Biol Chem
publication date: 1992-06-05T00:00:00
year: 1992
type: Academic Article
type: Article
type: Document
type: Information Resource

Actin stabilization by jasplakinolide enhances apoptosis induced by cytokine deprivation.
PubMed Identifier: 9933626
author list: Posey SC, Bierer BE
published in: The Journal of biological chemistry
information resource reference: Actin stabilization by jasplakinolide enhances apoptosis induced by cytokine deprivation. J Biol Chem. 1999 Feb 12; 274(7):4259-65.
journal title abbreviation: J Biol Chem
publication date: 1999-02-12T00:00:00
year: 1999
type: Academic Article
type: Article
type: Document
type: Information Resource

CD28/CTLA-4 and CD80/CD86 families: signaling and function.
PubMed Identifier: 10374692
author list: Slavik JM, Hutchcroft JE, Bierer BE
published in: Immunologic research
information resource reference: CD28/CTLA-4 and CD80/CD86 families: signaling and function. Immunol Res. 1999; 19(1):1-24.
journal title abbreviation: Immunol Res
publication date: 1999-01-01T00:00:00
year: 1999
type: Academic Article
type: Article
type: Document
type: Information Resource

The interaction of CD2 with its LFA-3 ligand expressed by autologous erythrocytes results in enhancement of B cell responses.
PubMed Identifier: 2460248
author list: Virella G, Rugeles MT, Hyman B, La Via M, Goust JM, Frankis M, Bierer BE
published in: Cellular immunology
information resource reference: The interaction of CD2 with its LFA-3 ligand expressed by autologous erythrocytes results in enhancement of B cell responses. Cell Immunol. 1988 Oct 15; 116(2):308-19.
journal title abbreviation: Cell Immunol
publication date: 1988-10-15T00:00:00
year: 1988
type: Academic Article
type: Article
type: Document
type: Information Resource

T-lymphocyte coactivator molecules.
PubMed Identifier: 11138627
author list: Salazar-Fontana LI, Bierer BE
published in: Current opinion in hematology
information resource reference: T-lymphocyte coactivator molecules. Curr Opin Hematol. 2001 Jan; 8(1):5-11.
journal title abbreviation: Curr Opin Hematol
publication date: 2001-01-01T00:00:00
year: 2001
type: Academic Article
type: Article
type: Document
type: Information Resource

Enhancing safety reporting in adult ambulatory oncology with a clinician champion: a practice innovation.
PubMed Identifier: 19525761
author list: Weingart SN, Price J, Duncombe D, Connor M, Conley K, Conlin GJ, Sullivan AM, Powell M, Ponte PR, Bierer BE
published in: Journal of nursing care quality
information resource reference: Enhancing safety reporting in adult ambulatory oncology with a clinician champion: a practice innovation. J Nurs Care Qual. 2009 Jul-Sep; 24(3):203-10.
journal title abbreviation: J Nurs Care Qual
publication date: 2009-07-01T00:00:00
year: 2009
type: Academic Article
type: Article
type: Document
type: Information Resource

Enhancement of T-cell activation by the CD43 molecule whose expression is defective in Wiskott-Aldrich syndrome.
PubMed Identifier: 2023632
author list: Park JK, Rosenstein YJ, Remold-O'Donnell E, Bierer BE, Rosen FS, Burakoff SJ
published in: Nature
information resource reference: Enhancement of T-cell activation by the CD43 molecule whose expression is defective in Wiskott-Aldrich syndrome. Nature. 1991 Apr 25; 350(6320):706-9.
journal title abbreviation: Nature
publication date: 1991-04-25T00:00:00
year: 1991
type: Academic Article
type: Article
type: Document
type: Information Resource

https://connects.catalyst.harvard.edu/Profiles/profile/825741
PubMed Identifier: 1382293
author list: Kaye RE, Fruman DA, Bierer BE, Albers MW, Zydowsky LD, Ho SI, Jin YJ, Castells MC, Schreiber SL, Walsh CT
published in: Proceedings of the National Academy of Sciences of the United States of America
information resource reference: Effects of cyclosporin A and FK506 on Fc epsilon receptor type I-initiated increases in cytokine mRNA in mouse bone marrow-derived progenitor mast cells: resistance to FK506 is associated with a deficiency in FK506-binding protein FKBP12. Proc Natl Acad Sci U S A. 1992 Sep 15; 89(18):8542-6.
journal title abbreviation: Proc Natl Acad Sci U S A
publication date: 1992-09-15T00:00:00
year: 1992
type: Academic Article
type: Article
type: Document
type: Information Resource
label: Effects of cyclosporin A and FK506 on Fc epsilon receptor type I-initiated increases in cytokine mRNA in mouse bone marrow-derived progenitor mast cells: resistance to FK506 is associated with a deficiency in FK506-binding protein FKBP12.

Association of p59(fyn) with the T lymphocyte costimulatory receptor CD2. Binding of the Fyn Src homology (SH) 3 domain is regulated by the Fyn SH2 domain.
PubMed Identifier: 9677430
author list: Lin H, Hutchcroft JE, Andoniou CE, Kamoun M, Band H, Bierer BE
published in: The Journal of biological chemistry
information resource reference: Association of p59(fyn) with the T lymphocyte costimulatory receptor CD2. Binding of the Fyn Src homology (SH) 3 domain is regulated by the Fyn SH2 domain. J Biol Chem. 1998 Jul 31; 273(31):19914-21.
journal title abbreviation: J Biol Chem
publication date: 1998-07-31T00:00:00
year: 1998
type: Academic Article
type: Article
type: Document
type: Information Resource

The APC-associated protein EB1 associates with components of the dynactin complex and cytoplasmic dynein intermediate chain.
PubMed Identifier: 10226031
author list: Berrueta L, Tirnauer JS, Schuyler SC, Pellman D, Bierer BE
published in: Current biology : CB
information resource reference: The APC-associated protein EB1 associates with components of the dynactin complex and cytoplasmic dynein intermediate chain. Curr Biol. 1999 Apr 22; 9(8):425-8.
journal title abbreviation: Curr Biol
publication date: 1999-04-22T00:00:00
year: 1999
type: Academic Article
type: Article
type: Document
type: Information Resource

Yeast Bim1p promotes the G1-specific dynamics of microtubules.
PubMed Identifier: 10352017
author list: Tirnauer JS, O'Toole E, Berrueta L, Bierer BE, Pellman D
published in: The Journal of cell biology
information resource reference: Yeast Bim1p promotes the G1-specific dynamics of microtubules. J Cell Biol. 1999 May 31; 145(5):993-1007.
journal title abbreviation: J Cell Biol
publication date: 1999-05-31T00:00:00
year: 1999
type: Academic Article
type: Article
type: Document
type: Information Resource

The effect of desferrithiocin, an oral iron chelator, on T-cell function.
PubMed Identifier: 2242426
author list: Bierer BE, Nathan DG
published in: Blood
information resource reference: The effect of desferrithiocin, an oral iron chelator, on T-cell function. Blood. 1990 Nov 15; 76(10):2052-9.
journal title abbreviation: Blood
publication date: 1990-11-15T00:00:00
year: 1990
type: Academic Article
type: Article
type: Document
type: Information Resource

Regulation of CXCR4 expression in human T lymphocytes by calcium and calcineurin.
PubMed Identifier: 14563373
author list: Cristillo AD, Bierer BE
published in: Molecular immunology
information resource reference: Regulation of CXCR4 expression in human T lymphocytes by calcium and calcineurin. Mol Immunol. 2003 Dec; 40(8):539-53.
journal title abbreviation: Mol Immunol
publication date: 2003-12-01T00:00:00
year: 2003
type: Academic Article
type: Article
type: Document
type: Information Resource

Treatment of chronic graft-versus-host disease with clofazimine.
PubMed Identifier: 9116272
author list: Lee SJ, Wegner SA, McGarigle CJ, Bierer BE, Antin JH
published in: Blood
information resource reference: Treatment of chronic graft-versus-host disease with clofazimine. Blood. 1997 Apr 01; 89(7):2298-302.
journal title abbreviation: Blood
publication date: 1997-04-01T00:00:00
year: 1997
type: Academic Article
type: Article
type: Document
type: Information Resource

Phenotypic and functional characterization of human cytolytic T cells lacking expression of CD5.
PubMed Identifier: 2452832
author list: Bierer BE, Nishimura Y, Burakoff SJ, Smith BR
published in: The Journal of clinical investigation
information resource reference: Phenotypic and functional characterization of human cytolytic T cells lacking expression of CD5. J Clin Invest. 1988 May; 81(5):1390-7.
journal title abbreviation: J Clin Invest
publication date: 1988-05-01T00:00:00
year: 1988
type: Academic Article
type: Article
type: Document
type: Information Resource

Probing immunosuppressant action with a nonnatural immunophilin ligand.
PubMed Identifier: 1700475
author list: Bierer BE, Somers PK, Wandless TJ, Burakoff SJ, Schreiber SL
published in: Science (New York, N.Y.)
information resource reference: Probing immunosuppressant action with a nonnatural immunophilin ligand. Science. 1990 Oct 26; 250(4980):556-9.
journal title abbreviation: Science
publication date: 1990-10-26T00:00:00
year: 1990
type: Academic Article
type: Article
type: Document
type: Information Resource

The effect of the immunosuppressant FK-506 on alternate pathways of T cell activation.
PubMed Identifier: 1705513
author list: Bierer BE, Schreiber SL, Burakoff SJ
published in: European journal of immunology
information resource reference: The effect of the immunosuppressant FK-506 on alternate pathways of T cell activation. Eur J Immunol. 1991 Feb; 21(2):439-45.
journal title abbreviation: Eur J Immunol
publication date: 1991-02-01T00:00:00
year: 1991
type: Academic Article
type: Article
type: Document
type: Information Resource

A monoclonal antibody to LFA-3, the CD2 ligand, specifically immobilizes major histocompatibility complex proteins.
PubMed Identifier: 2471647
author list: Bierer BE, Golan DE, Brown CS, Herrmann SH, Burakoff SJ
published in: European journal of immunology
information resource reference: A monoclonal antibody to LFA-3, the CD2 ligand, specifically immobilizes major histocompatibility complex proteins. Eur J Immunol. 1989 Apr; 19(4):661-5.
journal title abbreviation: Eur J Immunol
publication date: 1989-04-01T00:00:00
year: 1989
type: Academic Article
type: Article
type: Document
type: Information Resource

Prevention and treatment of sickle cell crisis by induced hyponatremia.
PubMed Identifier: 7245573
author list: Rosa RM, Bierer B, Thomas R, Stoff JS, Kruskall M, Robinson S, Bunn HF, Epstein FH
published in: Transactions of the Association of American Physicians
information resource reference: Prevention and treatment of sickle cell crisis by induced hyponatremia. Trans Assoc Am Physicians. 1980; 93:164-74.
journal title abbreviation: Trans Assoc Am Physicians
publication date: 1980-01-01T00:00:00
year: 1980
type: Academic Article
type: Article
type: Document
type: Information Resource

Recombinant human interleukin-1 receptor antagonist in the treatment of steroid-resistant graft-versus-host disease.
PubMed Identifier: 8049450
author list: Antin JH, Weinstein HJ, Guinan EC, McCarthy P, Bierer BE, Gilliland DG, Parsons SK, Ballen KK, Rimm IJ, Falzarano G
published in: Blood
information resource reference: Recombinant human interleukin-1 receptor antagonist in the treatment of steroid-resistant graft-versus-host disease. Blood. 1994 Aug 15; 84(4):1342-8.
journal title abbreviation: Blood
publication date: 1994-08-15T00:00:00
year: 1994
type: Academic Article
type: Article
type: Document
type: Information Resource

Signaling through CD28/CTLA-4 family receptors: puzzling participation of phosphatidylinositol-3 kinase.
PubMed Identifier: 8666770
author list: Hutchcroft JE, Bierer BE
published in: Journal of immunology (Baltimore, Md. : 1950)
information resource reference: Signaling through CD28/CTLA-4 family receptors: puzzling participation of phosphatidylinositol-3 kinase. J Immunol. 1996 Jun 01; 156(11):4071-4.
journal title abbreviation: J Immunol
publication date: 1996-06-01T00:00:00
year: 1996
type: Academic Article
type: Article
type: Document
type: Information Resource

Patient-reported safety and quality of care in outpatient oncology.
PubMed Identifier: 17370919
author list: Weingart SN, Price J, Duncombe D, Connor M, Sommer K, Conley KA, Bierer BE, Ponte PR
published in: Joint Commission journal on quality and patient safety
information resource reference: Patient-reported safety and quality of care in outpatient oncology. Jt Comm J Qual Patient Saf. 2007 Feb; 33(2):83-94.
journal title abbreviation: Jt Comm J Qual Patient Saf
publication date: 2007-02-01T00:00:00
year: 2007
type: Academic Article
type: Article
type: Document
type: Information Resource

The biologic roles of CD2, CD4, and CD8 in T-cell activation.
PubMed Identifier: 2653377
author list: Bierer BE, Sleckman BP, Ratnofsky SE, Burakoff SJ
published in: Annual review of immunology
information resource reference: The biologic roles of CD2, CD4, and CD8 in T-cell activation. Annu Rev Immunol. 1989; 7:579-99.
journal title abbreviation: Annu Rev Immunol
publication date: 1989-01-01T00:00:00
year: 1989
type: Academic Article
type: Article
type: Document
type: Information Resource

Immunosuppressants FK506 and rapamycin function as reversal agents of the multidrug resistance phenotype.
PubMed Identifier: 1381629
author list: Arceci RJ, Stieglitz K, Bierer BE
published in: Blood
information resource reference: Immunosuppressants FK506 and rapamycin function as reversal agents of the multidrug resistance phenotype. Blood. 1992 Sep 15; 80(6):1528-36.
journal title abbreviation: Blood
publication date: 1992-09-15T00:00:00
year: 1992
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1006725
type: Authorship
author rank in publication: 7
linked author: Bierer, Barbara
linked information resource: What do revised U.S. rules mean for human research?

Authorship 1001386
type: Authorship
author rank in publication: 4
linked author: Bierer, Barbara
linked information resource: Forensic bitemark identification: weak foundations, exaggerated claims.

Authorship 1001294
type: Authorship
author rank in publication: 1
linked author: Bierer, Barbara
linked information resource: Data Authorship as an Incentive to Data Sharing.

Data Authorship as an Incentive to Data Sharing.
PubMed Identifier: 28745980
author list: Bierer BE, Crosas M, Pierce HH
published in: The New England journal of medicine
information resource reference: Data Authorship as an Incentive to Data Sharing. N Engl J Med. 2017 07 27; 377(4):402.
journal title abbreviation: N Engl J Med
publication date: 2017-07-27T00:00:00
year: 2017
type: Academic Article
type: Article
type: Document
type: Information Resource

Forensic bitemark identification: weak foundations, exaggerated claims.
PubMed Identifier: 28852538
author list: Saks MJ, Albright T, Bohan TL, Bierer BE, Bowers CM, Bush MA, Bush PJ, Casadevall A, Cole SA, Denton MB, Diamond SS, Dioso-Villa R, Epstein J, Faigman D, Faigman L, Fienberg SE, Garrett BL, Giannelli PC, Greely HT, Imwinkelried E, Jamieson A, Kafadar K, Kassirer JP, Koehler J', Korn D, Mnookin J, Morrison AB, Murphy E, Peerwani N, Peterson JL, Risinger DM, Sensabaugh GF, Spiegelman C, Stern H, Thompson WC, Wayman JL, Zabell S, Zumwalt RE
published in: Journal of law and the biosciences
information resource reference: Forensic bitemark identification: weak foundations, exaggerated claims. J Law Biosci. 2016 Dec; 3(3):538-575.
journal title abbreviation: J Law Biosci
publication date: 2016-11-23T00:00:00
year: 2016
type: Academic Article
type: Article
type: Document
type: Information Resource

What do revised U.S. rules mean for human research?
PubMed Identifier: 28818933
author list: Nichols L, Brako L, Rivera SM, Tahmassian A, Jones MF, Pierce HH, Bierer BE
published in: Science (New York, N.Y.)
information resource reference: What do revised U.S. rules mean for human research? Science. 2017 Aug 18; 357(6352):650-651.
journal title abbreviation: Science
publication date: 2017-08-18T00:00:00
year: 2017
type: Academic Article
type: Article
type: Document
type: Information Resource

A study of induced hyponatremia in the prevention and treatment of sickle-cell crisis.
PubMed Identifier: 6999348
author list: Rosa RM, Bierer BE, Thomas R, Stoff JS, Kruskall M, Robinson S, Bunn HF, Epstein FH
published in: The New England journal of medicine
information resource reference: A study of induced hyponatremia in the prevention and treatment of sickle-cell crisis. N Engl J Med. 1980 Nov 13; 303(20):1138-43.
journal title abbreviation: N Engl J Med
publication date: 1980-11-13T00:00:00
year: 1980
type: Academic Article
type: Article
type: Document
type: Information Resource

Cyclosporin A and FK506: molecular mechanisms of immunosuppression and probes for transplantation biology.
PubMed Identifier: 7694595
author list: Bierer BE, Holländer G, Fruman D, Burakoff SJ
published in: Current opinion in immunology
information resource reference: Cyclosporin A and FK506: molecular mechanisms of immunosuppression and probes for transplantation biology. Curr Opin Immunol. 1993 Oct; 5(5):763-73.
journal title abbreviation: Curr Opin Immunol
publication date: 1993-10-01T00:00:00
year: 1993
type: Academic Article
type: Article
type: Document
type: Information Resource

Intracellular mediators regulate CD2 lateral diffusion and cytoplasmic Ca2+ mobilization upon CD2-mediated T cell activation.
PubMed Identifier: 7696499
author list: Liu SJ, Hahn WC, Bierer BE, Golan DE
published in: Biophysical journal
information resource reference: Intracellular mediators regulate CD2 lateral diffusion and cytoplasmic Ca2+ mobilization upon CD2-mediated T cell activation. Biophys J. 1995 Feb; 68(2):459-70.
journal title abbreviation: Biophys J
publication date: 1995-02-01T00:00:00
year: 1995
type: Academic Article
type: Article
type: Document
type: Information Resource

EB1 proteins regulate microtubule dynamics, cell polarity, and chromosome stability.
PubMed Identifier: 10811817
author list: Tirnauer JS, Bierer BE
published in: The Journal of cell biology
information resource reference: EB1 proteins regulate microtubule dynamics, cell polarity, and chromosome stability. J Cell Biol. 2000 May 15; 149(4):761-6.
journal title abbreviation: J Cell Biol
publication date: 2000-05-15T00:00:00
year: 2000
type: Academic Article
type: Article
type: Document
type: Information Resource

CD28 engagement promotes actin polymerization through the activation of the small Rho GTPase Cdc42 in human T cells.
PubMed Identifier: 12928366
author list: Salazar-Fontana LI, Barr V, Samelson LE, Bierer BE
published in: Journal of immunology (Baltimore, Md. : 1950)
information resource reference: CD28 engagement promotes actin polymerization through the activation of the small Rho GTPase Cdc42 in human T cells. J Immunol. 2003 Sep 01; 171(5):2225-32.
journal title abbreviation: J Immunol
publication date: 2003-09-01T00:00:00
year: 2003
type: Academic Article
type: Article
type: Document
type: Information Resource

Immunophilins in protein folding and immunosuppression.
PubMed Identifier: 7513288
author list: Fruman DA, Burakoff SJ, Bierer BE
published in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology
information resource reference: Immunophilins in protein folding and immunosuppression. FASEB J. 1994 Apr 01; 8(6):391-400.
journal title abbreviation: FASEB J
publication date: 1994-04-01T00:00:00
year: 1994
type: Academic Article
type: Article
type: Document
type: Information Resource

Mechanisms of immunosuppression by FK506. Preservation of T cell transmembrane signal transduction.
PubMed Identifier: 1694317
author list: Bierer BE, Schreiber SL, Burakoff SJ
published in: Transplantation
information resource reference: Mechanisms of immunosuppression by FK506. Preservation of T cell transmembrane signal transduction. Transplantation. 1990 Jun; 49(6):1168-70.
journal title abbreviation: Transplantation
publication date: 1990-06-01T00:00:00
year: 1990
type: Academic Article
type: Article
type: Document
type: Information Resource

Functional CD2 mutants unable to bind to, or be stimulated by, LFA-3.
PubMed Identifier: 1689346
author list: Wolff HL, Burakoff SJ, Bierer BE
published in: Journal of immunology (Baltimore, Md. : 1950)
information resource reference: Functional CD2 mutants unable to bind to, or be stimulated by, LFA-3. J Immunol. 1990 Feb 15; 144(4):1215-20.
journal title abbreviation: J Immunol
publication date: 1990-02-15T00:00:00
year: 1990
type: Academic Article
type: Article
type: Document
type: Information Resource

Ex vivo rapamycin generates donor Th2 cells that potently inhibit graft-versus-host disease and graft-versus-tumor effects via an IL-4-dependent mechanism.
PubMed Identifier: 16237064
author list: Foley JE, Jung U, Miera A, Borenstein T, Mariotti J, Eckhaus M, Bierer BE, Fowler DH
published in: Journal of immunology (Baltimore, Md. : 1950)
information resource reference: Ex vivo rapamycin generates donor Th2 cells that potently inhibit graft-versus-host disease and graft-versus-tumor effects via an IL-4-dependent mechanism. J Immunol. 2005 Nov 01; 175(9):5732-43.
journal title abbreviation: J Immunol
publication date: 2005-11-01T00:00:00
year: 2005
type: Academic Article
type: Article
type: Document
type: Information Resource

T cell adhesion molecules.
PubMed Identifier: 2838364
author list: Bierer BE, Burakoff SJ
published in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology
information resource reference: T cell adhesion molecules. FASEB J. 1988 Jul; 2(10):2584-90.
journal title abbreviation: FASEB J
publication date: 1988-07-01T00:00:00
year: 1988
type: Academic Article
type: Article
type: Document
type: Information Resource

Regulation of cytotoxic T lymphocyte-mediated graft rejection following bone marrow transplantation.
PubMed Identifier: 3061078
author list: Bierer BE, Emerson SG, Antin J, Maziarz R, Rappeport JM, Smith BR, Burakoff SJ
published in: Transplantation
information resource reference: Regulation of cytotoxic T lymphocyte-mediated graft rejection following bone marrow transplantation. Transplantation. 1988 Dec; 46(6):835-9.
journal title abbreviation: Transplantation
publication date: 1988-12-01T00:00:00
year: 1988
type: Academic Article
type: Article
type: Document
type: Information Resource

Abnormal cytolytic activity of lymphocyte function-associated antigen-1-deficient human cytolytic T lymphocyte clones.
PubMed Identifier: 3534001
author list: Mentzer SJ, Bierer BE, Anderson DC, Springer TA, Burakoff SJ
published in: The Journal of clinical investigation
information resource reference: Abnormal cytolytic activity of lymphocyte function-associated antigen-1-deficient human cytolytic T lymphocyte clones. J Clin Invest. 1986 Nov; 78(5):1387-91.
journal title abbreviation: J Clin Invest
publication date: 1986-11-01T00:00:00
year: 1986
type: Academic Article
type: Article
type: Document
type: Information Resource

Selective depletion of bone marrow T lymphocytes with anti-CD5 monoclonal antibodies: effective prophylaxis for graft-versus-host disease in patients with hematologic malignancies.
PubMed Identifier: 1717080
author list: Antin JH, Bierer BE, Smith BR, Ferrara J, Guinan EC, Sieff C, Golan DE, Macklis RM, Tarbell NJ, Lynch E
published in: Blood
information resource reference: Selective depletion of bone marrow T lymphocytes with anti-CD5 monoclonal antibodies: effective prophylaxis for graft-versus-host disease in patients with hematologic malignancies. Blood. 1991 Oct 15; 78(8):2139-49.
journal title abbreviation: Blood
publication date: 1991-10-15T00:00:00
year: 1991
type: Academic Article
type: Article
type: Document
type: Information Resource

Interaction of CD2 with its ligand, LFA-3, in human T cell proliferation.
PubMed Identifier: 2834437
author list: Bierer BE, Barbosa J, Herrmann S, Burakoff SJ
published in: Journal of immunology (Baltimore, Md. : 1950)
information resource reference: Interaction of CD2 with its ligand, LFA-3, in human T cell proliferation. J Immunol. 1988 May 15; 140(10):3358-63.
journal title abbreviation: J Immunol
publication date: 1988-05-15T00:00:00
year: 1988
type: Academic Article
type: Article
type: Document
type: Information Resource

Cyclosporin A, FK506, and rapamycin: binding to immunophilins and biological action.
PubMed Identifier: 7524531
author list: Bierer BE
published in: Chemical immunology
information resource reference: Cyclosporin A, FK506, and rapamycin: binding to immunophilins and biological action. Chem Immunol. 1994; 59:128-55.
journal title abbreviation: Chem Immunol
publication date: 1994-01-01T00:00:00
year: 1994
type: Academic Article
type: Article
type: Document
type: Information Resource

Association of CD2 with tubulin. Evidence for a role of the cytoskeleton in T cell activation.
PubMed Identifier: 8095265
author list: Offringa R, Bierer BE
published in: The Journal of biological chemistry
information resource reference: Association of CD2 with tubulin. Evidence for a role of the cytoskeleton in T cell activation. J Biol Chem. 1993 Mar 05; 268(7):4979-88.
journal title abbreviation: J Biol Chem
publication date: 1993-03-05T00:00:00
year: 1993
type: Academic Article
type: Article
type: Document
type: Information Resource

75 Francis St
type: Address
address line 1: Brigham and Women'
address line 2: Thorn 1403-C
address line 3: 75 Francis St
city: Boston
postal code: 02115
state or province: MA

Expression and function of a CD5 cDNA in human and murine T cells.
PubMed Identifier: 2454193
author list: Nishimura Y, Bierer BE, Jones WK, Jones NH, Strominger JL, Burakoff SJ
published in: European journal of immunology
information resource reference: Expression and function of a CD5 cDNA in human and murine T cells. Eur J Immunol. 1988 May; 18(5):747-53.
journal title abbreviation: Eur J Immunol
publication date: 1988-05-01T00:00:00
year: 1988
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1032852
type: Authorship
author rank in publication: 8
linked author: Bierer, Barbara
linked information resource: Sharing and reuse of individual participant data from clinical trials: principles and recommendations.

Sharing and reuse of individual participant data from clinical trials: principles and recommendations.
PubMed Identifier: 29247106
author list: Ohmann C, Banzi R, Canham S, Battaglia S, Matei M, Ariyo C, Becnel L, Bierer B, Bowers S, Clivio L, Dias M, Druml C, Faure H, Fenner M, Galvez J, Ghersi D, Gluud C, Groves T, Houston P, Karam G, Kalra D, Knowles RL, Krleža-Jeric K, Kubiak C, Kuchinke W, Kush R, Lukkarinen A, Marques PS, Newbigging A, O'Callaghan J, Ravaud P, Schlünder I, Shanahan D, Sitter H, Spalding D, Tudur-Smith C, van Reusel P, van Veen EB, Visser GR, Wilson J, Demotes-Mainard J
published in: BMJ open
information resource reference: Sharing and reuse of individual participant data from clinical trials: principles and recommendations. BMJ Open. 2017 Dec 14; 7(12):e018647.
journal title abbreviation: BMJ Open
publication date: 2017-12-14T00:00:00
year: 2017
type: Academic Article
type: Article
type: Document
type: Information Resource

Lateral mobility of class I histocompatibility antigens in B lymphoblastoid cell membranes: modulation by cross-linking and effect of cell density.
PubMed Identifier: 3115995
author list: Bierer BE, Herrmann SH, Brown CS, Burakoff SJ, Golan DE
published in: The Journal of cell biology
information resource reference: Lateral mobility of class I histocompatibility antigens in B lymphoblastoid cell membranes: modulation by cross-linking and effect of cell density. J Cell Biol. 1987 Sep; 105(3):1147-52.
journal title abbreviation: J Cell Biol
publication date: 1987-09-01T00:00:00
year: 1987
type: Academic Article
type: Article
type: Document
type: Information Resource

Activation-dependent phosphorylation of the T-lymphocyte surface receptor CD28 and associated proteins.
PubMed Identifier: 7512728
author list: Hutchcroft JE, Bierer BE
published in: Proceedings of the National Academy of Sciences of the United States of America
information resource reference: Activation-dependent phosphorylation of the T-lymphocyte surface receptor CD28 and associated proteins. Proc Natl Acad Sci U S A. 1994 Apr 12; 91(8):3260-4.
journal title abbreviation: Proc Natl Acad Sci U S A
publication date: 1994-04-12T00:00:00
year: 1994
type: Academic Article
type: Article
type: Document
type: Information Resource

Differential phosphorylation of the T lymphocyte costimulatory receptor CD28. Activation-dependent changes and regulation by protein kinase C.
PubMed Identifier: 8662792
author list: Hutchcroft JE, Tsai B, Bierer BE
published in: The Journal of biological chemistry
information resource reference: Differential phosphorylation of the T lymphocyte costimulatory receptor CD28. Activation-dependent changes and regulation by protein kinase C. J Biol Chem. 1996 Jun 07; 271(23):13362-70.
journal title abbreviation: J Biol Chem
publication date: 1996-06-07T00:00:00
year: 1996
type: Academic Article
type: Article
type: Document
type: Information Resource

Structural organization of the genes encoding human and murine FK506-binding protein (FKBP) 13 and comparison to FKBP1.
PubMed Identifier: 7505249
author list: Hendrickson BA, Zhang W, Craig RJ, Jin YJ, Bierer BE, Burakoff S, DiLella AG
published in: Gene
information resource reference: Structural organization of the genes encoding human and murine FK506-binding protein (FKBP) 13 and comparison to FKBP1. Gene. 1993 Dec 08; 134(2):271-5.
journal title abbreviation: Gene
publication date: 1993-12-08T00:00:00
year: 1993
type: Academic Article
type: Article
type: Document
type: Information Resource

Activation of 70-kDa S6 kinase, induced by the cytokines interleukin-3 and erythropoietin and inhibited by rapamycin, is not an absolute requirement for cell proliferation.
PubMed Identifier: 7957559
author list: Calvo V, Wood M, Gjertson C, Vik T, Bierer BE
published in: European journal of immunology
information resource reference: Activation of 70-kDa S6 kinase, induced by the cytokines interleukin-3 and erythropoietin and inhibited by rapamycin, is not an absolute requirement for cell proliferation. Eur J Immunol. 1994 Nov; 24(11):2664-71.
journal title abbreviation: Eur J Immunol
publication date: 1994-11-01T00:00:00
year: 1994
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1042013
type: Authorship
author rank in publication: 1
linked author: Bierer, Barbara
linked information resource: Venipuncture Procedures: Sources of Human Peripheral Blood Cells, Serum, and Plasma.

Authorship 1042143
type: Authorship
author rank in publication: 1
linked author: Bierer, Barbara
linked information resource: Universal Precautions: Necessary Safety Procedures When Handling Human Blood, Body Fluids, and Specimens.

Venipuncture Procedures: Sources of Human Peripheral Blood Cells, Serum, and Plasma.
PubMed Identifier: 28762484
author list: Bierer BE, Strober W
published in: Current protocols in immunology
information resource reference: Venipuncture Procedures: Sources of Human Peripheral Blood Cells, Serum, and Plasma. Curr Protoc Immunol. 2017 Aug 01; 118:A.3F.1-A.3F.5.
journal title abbreviation: Curr Protoc Immunol
publication date: 2017-08-01T00:00:00
year: 2017
type: Academic Article
type: Article
type: Document
type: Information Resource

Universal Precautions: Necessary Safety Procedures When Handling Human Blood, Body Fluids, and Specimens.
PubMed Identifier: 28762486
author list: Bierer BE
published in: Current protocols in immunology
information resource reference: Universal Precautions: Necessary Safety Procedures When Handling Human Blood, Body Fluids, and Specimens. Curr Protoc Immunol. 2017 Aug 01; 118:A.3P.1-A.3P.3.
journal title abbreviation: Curr Protoc Immunol
publication date: 2017-08-01T00:00:00
year: 2017
type: Academic Article
type: Article
type: Document
type: Information Resource

Humoral hypercalcemia of malignancy. Release of a prostaglandin-stimulating bone-resorbing factor in vitro by human transitional-cell carcinoma cells.
PubMed Identifier: 3003159
author list: Bringhurst FR, Bierer BE, Godeau F, Neyhard N, Varner V, Segre GV
published in: The Journal of clinical investigation
information resource reference: Humoral hypercalcemia of malignancy. Release of a prostaglandin-stimulating bone-resorbing factor in vitro by human transitional-cell carcinoma cells. J Clin Invest. 1986 Feb; 77(2):456-64.
journal title abbreviation: J Clin Invest
publication date: 1986-02-01T00:00:00
year: 1986
type: Academic Article
type: Article
type: Document
type: Information Resource

The adenomatous polyposis coli-binding protein EB1 is associated with cytoplasmic and spindle microtubules.
PubMed Identifier: 9724749
author list: Berrueta L, Kraeft SK, Tirnauer JS, Schuyler SC, Chen LB, Hill DE, Pellman D, Bierer BE
published in: Proceedings of the National Academy of Sciences of the United States of America
information resource reference: The adenomatous polyposis coli-binding protein EB1 is associated with cytoplasmic and spindle microtubules. Proc Natl Acad Sci U S A. 1998 Sep 01; 95(18):10596-601.
journal title abbreviation: Proc Natl Acad Sci U S A
publication date: 1998-09-01T00:00:00
year: 1998
type: Academic Article
type: Article
type: Document
type: Information Resource

Rapamycin-induced inhibition of the 70-kilodalton S6 protein kinase.
PubMed Identifier: 1380182
author list: Price DJ, Grove JR, Calvo V, Avruch J, Bierer BE
published in: Science (New York, N.Y.)
information resource reference: Rapamycin-induced inhibition of the 70-kilodalton S6 protein kinase. Science. 1992 Aug 14; 257(5072):973-7.
journal title abbreviation: Science
publication date: 1992-08-14T00:00:00
year: 1992
type: Academic Article
type: Article
type: Document
type: Information Resource

T cell receptor activation of a ribosomal S6 kinase activity.
PubMed Identifier: 1537381
author list: Calvo V, Bierer BE, Vik TA
published in: European journal of immunology
information resource reference: T cell receptor activation of a ribosomal S6 kinase activity. Eur J Immunol. 1992 Feb; 22(2):457-62.
journal title abbreviation: Eur J Immunol
publication date: 1992-02-01T00:00:00
year: 1992
type: Academic Article
type: Article
type: Document
type: Information Resource

CD43, a molecule defective in Wiskott-Aldrich syndrome, binds ICAM-1.
PubMed Identifier: 1683685
author list: Rosenstein Y, Park JK, Hahn WC, Rosen FS, Bierer BE, Burakoff SJ
published in: Nature
information resource reference: CD43, a molecule defective in Wiskott-Aldrich syndrome, binds ICAM-1. Nature. 1991 Nov 21; 354(6350):233-5.
journal title abbreviation: Nature
publication date: 1991-11-21T00:00:00
year: 1991
type: Academic Article
type: Article
type: Document
type: Information Resource

Disruption of T cell development and repertoire selection by calcineurin inhibition in vivo.
PubMed Identifier: 7526495
author list: Holländer GA, Fruman DA, Bierer BE, Burakoff SJ
published in: Transplantation
information resource reference: Disruption of T cell development and repertoire selection by calcineurin inhibition in vivo. Transplantation. 1994 Nov 15; 58(9):1037-43.
journal title abbreviation: Transplantation
publication date: 1994-11-15T00:00:00
year: 1994
type: Academic Article
type: Article
type: Document
type: Information Resource

FK506 binding protein 12 mediates sensitivity to both FK506 and rapamycin in murine mast cells.
PubMed Identifier: 7533090
author list: Fruman DA, Wood MA, Gjertson CK, Katz HR, Burakoff SJ, Bierer BE
published in: European journal of immunology
information resource reference: FK506 binding protein 12 mediates sensitivity to both FK506 and rapamycin in murine mast cells. Eur J Immunol. 1995 Feb; 25(2):563-71.
journal title abbreviation: Eur J Immunol
publication date: 1995-02-01T00:00:00
year: 1995
type: Academic Article
type: Article
type: Document
type: Information Resource

Overlapping but nonidentical binding sites on CD2 for CD58 and a second ligand CD59.
PubMed Identifier: 1377404
author list: Hahn WC, Menu E, Bothwell AL, Sims PJ, Bierer BE
published in: Science (New York, N.Y.)
information resource reference: Overlapping but nonidentical binding sites on CD2 for CD58 and a second ligand CD59. Science. 1992 Jun 26; 256(5065):1805-7.
journal title abbreviation: Science
publication date: 1992-06-26T00:00:00
year: 1992
type: Academic Article
type: Article
type: Document
type: Information Resource