Effect of inhaled nitric oxide on right heart function during exercise. Submitted. 2004.
Effect of inhaled nitric oxide on right heart function during exercise
J.J. Tolle, MD, D.M. Systrom, MD, J.C. Wain, MD, L.C. Ginns, MD. Massachusetts General Hospita, Harvard Medical School, Boston, MA
Exercise Limitation Differs in Recipients of Lung Transplantation from Living vs. Deceased Donors in Cystic Fibrosis. Am J Respir Crit Care Med. 2006.
Exercise Limitation Differs in Recipients of Lung Transplantation from Living vs. Deceased Donors in Cystic Fibrosis
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Pulmonary haemodynamics and mortality in chronic hypersensitivity pneumonitis. Eur Respir J. 2018 06; 51(6).
Pulmonary haemodynamics and mortality in chronic hypersensitivity pneumonitis.
Deep vein thrombosis and pulmonary thromboembolism. In: Fishman, Hoffman, Klausner, Thaler, eds. Medicine. 4th ed. Philadelphia: JB Lippincpott Co. 1996; 109-15.
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Pulmonary hypertension roundtable: identifying the key issues in exercise testing
Baggish AL, Fulco CS, Muza S, Rock PB, Beidleman B, Cymerman A, Yared K, Fagenholz P, Systrom D, Wood MJ, Weyman AE, Picard MH, Harris NS
The impact of moderate-altitude staging on pulmonary arterial hemodynamics after ascent to high altitude. High Alt Med Biol. 2010; 11(2):139-45.
The impact of moderate-altitude staging on pulmonary arterial hemodynamics after ascent to high altitude.
McCabe C, Oliveira RKF, Rahaghi F, Faria-Urbina M, Howard L, Axell RG, Priest AN, Waxman AB, Systrom DM
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Right ventriculo-arterial uncoupling and impaired contractile reserve in obese patients with unexplained exercise intolerance.
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Pulmonary vascular response patterns during exercise in left ventricular systolic dysfunction predict exercise capacity and outcomes.
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A novel G15762A mutation in the mitochondrial cytochrome b gene
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Fleischman A, Makimura H, Stanley TL, McCarthy MA, Kron M, Sun N, Chuzi S, Hrovat MI, Systrom DM, Grinspoon SK
The Journal of clinical endocrinology and metabolism
Skeletal muscle phosphocreatine recovery after submaximal exercise in children and young and middle-aged adults. J Clin Endocrinol Metab. 2010 Sep; 95(9):E69-74.
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Case records of the Massachusetts General Hospital. Case 19-2005. A 17-year-old girl with respiratory distress and hemiparesis after surviving a tsunami.
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Maron BA, Cockrill BA, Waxman AB, Systrom DM
The invasive cardiopulmonary exercise test. Circulation. 2013 Mar 12; 127(10):1157-64.
The invasive cardiopulmonary exercise test.
In: Progress In Respiratory Research: Clinical Exercise Testing. ed: Weisman IM, Zeballos RJ.
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Systrom DM, Montes De Oca M, Fessler HE, Schols A
COPD: Extrapulmonary manifestation. 2004; 169:A770.
Ventilatory control and skeletal muscle pHi during recovery from exercise in the human. Submitted. 2004.
Ventilatory control and skeletal muscle pHi during recovery from exercise in the human
Lewis GD, Shah R, Shahzad K, Camuso JM, Pappagianopoulos PP, Hung J, Tawakol A, Gerszten RE, Systrom DM, Bloch KD, Semigran MJ
Sildenafil improves exercise capacity and quality of life in patients with systolic heart failure and secondary pulmonary hypertension. Circulation. 2007 Oct 02; 116(14):1555-62.
Sildenafil improves exercise capacity and quality of life in patients with systolic heart failure and secondary pulmonary hypertension.
Tolle JJ, Waxman AB, Van Horn TL, Pappagianopoulos PP, Systrom DM
Exercise-induced pulmonary arterial hypertension. Circulation. 2008 Nov 18; 118(21):2183-9.
Exercise-induced pulmonary arterial hypertension.
Lewis GD, Lachmann J, Camuso J, Lepore JJ, Shin J, Martinovic ME, Systrom DM, Bloch KD, Semigran MJ
Sildenafil improves exercise hemodynamics and oxygen uptake in patients with systolic heart failure. Circulation. 2007 Jan 02; 115(1):59-66.
Sildenafil improves exercise hemodynamics and oxygen uptake in patients with systolic heart failure.
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Case records of the Massachusetts General Hospital
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Case Records of the Massachusetts General Hospital
J.J. Tolle, MD, A.B. Waxman, MD. D.M. Systrom, MD. Massachusetts General Hospital, Harvard Medical School, Boston, MA
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Exercise-Induced Pulmonary Arterial Hypertension
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Herlihy JP, Venegas JG, Systrom DM, Greene RE, McKusick KA, Wain JC, Ginns LC
American journal of respiratory and critical care medicine
Expiratory flow pattern following single-lung transplantation in emphysema. Am J Respir Crit Care Med. 1994 Dec; 150(6 Pt 1):1684-9.
Expiratory flow pattern following single-lung transplantation in emphysema.
Larson DE, Hesslink RL, Hrovat MI, Fishman RS, Systrom DM
Journal of applied physiology (Bethesda, Md. : 1985)
Dietary effects on exercising muscle metabolism and performance by 31P-MRS. J Appl Physiol (1985). 1994 Sep; 77(3):1108-15.
Dietary effects on exercising muscle metabolism and performance by 31P-MRS.
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Salahi F, Systrom D, DiCola V, Boucher C, Hand R, Kanarek DJ, Harthorne J.W
Cardiopulmonary exercise testing in DDD compared to VVI pacing modes. AM J Noninvas Cardiol. 1987; 1:244-50.
Cardiopulmonary exercise testing in DDD compared to VVI pacing modes
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Lewis GD, Farrell L, Wood MJ, Martinovic M, Arany Z, Rowe GC, Souza A, Cheng S, McCabe EL, Yang E, Shi X, Deo R, Roth FP, Asnani A, Rhee EP, Systrom DM, Semigran MJ, Vasan RS, Carr SA, Wang TJ, Sabatine MS, Clish CB, Gerszten RE
Metabolic signatures of exercise in human plasma. Sci Transl Med. 2010 May 26; 2(33):33ra37.
Metabolic signatures of exercise in human plasma.
Murphy RM, Shah RV, Malhotra R, Pappagianopoulos PP, Hough SS, Systrom DM, Semigran MJ, Lewis GD
Exercise oscillatory ventilation in systolic heart failure: an indicator of impaired hemodynamic response to exercise. Circulation. 2011 Sep 27; 124(13):1442-51.
Exercise oscillatory ventilation in systolic heart failure: an indicator of impaired hemodynamic response to exercise.
J.J. Tolle, MD, A.B. Waxman, MD, PhD, D.M. Systrom, MD, Boston, MA
Abnormal Systemic O2 Extraction During Incremental Exercise in Pulmonary Hypertension. Am J Respir Crit Care Med. 2005; A498.
Abnormal Systemic O2 Extraction During Incremental Exercise in Pulmonary Hypertension
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P.L. Gordan, MD, J.J. Tolle, MD, P.P. Pappagianopoulos, D.M. Systrom, MD. Pulmonary and Critical Care Unit. Massachusetts General Hospital, Harvard Medical School, Boston, MA
Skeletal Muscle Ventilatory Chemoreflex during Exercise with Repetitive Partial Circulatory Occlusion. Am J Respir Crit Care Med. 2006.
Skeletal Muscle Ventilatory Chemoreflex during Exercise with Repetitive Partial Circulatory Occlusion
Systrom DM, Kao A, Sheridan R, Cash S, Ryan E, Ferrara S
A 17-year-old girl with respiratory distress and hemiparesis after surviving a tsunami. N Engl J Med. 2005; 352:2628-36.
A 17-year-old girl with respiratory distress and hemiparesis after surviving a tsunami
The skeletal muscle chemoreflex in exercise ventilatory control. In: Kent Pandolf, Nobuakira Takeda and Pawan K. Singal, ed. Adaptation Biology and Medicine. Narosa Publishing House. 1999; 2:236-45.
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Case records of the Massachusetts General Hospital. Case 9-2005. A 67-year-old man with acute respiratory failure.
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Skeletal muscle mitochodrial dysfunction in pulmonary arterial hypertension. Am j Respir Crit Care Med. 2008; 177:A293.
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Oelberg DA, Systrom DM, Markowitz DH, Zorb SL, Wright C, Wain JC, Ginns LC
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation
Exercise performance in cystic fibrosis before and after bilateral lung transplantation. J Heart Lung Transplant. 1998 Nov; 17(11):1104-12.
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Abnormal transpulmonary metabolite flux in exercise induced pulmonary arterial hypertension. Am J Respir Crit Care Med. 2009; 179:A4131.
Abnormal transpulmonary metabolite flux in exercise induced pulmonary arterial hypertension
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Determinants of abnormal maximum oxygen uptake following lung transplantation for chronic obstructive pulmonary disease
Acute Asthma Algorithm. The standard reference in the MGH EW for diagnosing and treating acute asthma. Commissioned by MGH Emergency Dept. Utilized in ongoing multicenter trial. 1988.
Acute Asthma Algorithm. The standard reference in the MGH EW for diagnosing and treating acute asthma. Commissioned by MGH Emergency Dept. Utilized in ongoing multicenter trial
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The respiratory system. In: Strauss RH, ed. Sports Medicine. 2d Edition. Philadelphia
Gregory D. Lewis, Laurie Farrell, Amanda Souza, Maryann Martinovic, David M. Systrom, Marc J. Semigran, Malissa J. Wood, Steven A. Carr, Marc S. Sabatine, Clary B. Clish, and Robert E. Gerszten
Novel Metabolic Signatures of Human Exercise Performance. TBA. 2010.
Novel Metabolic Signatures of Human Exercise Performance
Platz E, Merz A, Silverman M, Lewis E, Groarke JD, Waxman A, Systrom D
Association between lung ultrasound findings and invasive exercise haemodynamics in patients with undifferentiated dyspnoea. ESC Heart Fail. 2019 02; 6(1):202-207.
Association between lung ultrasound findings and invasive exercise haemodynamics in patients with undifferentiated dyspnoea.
A.V. LaRaia, MD, G.D. Lewis, MD, P.P. Pappagianopoulos, M.D., M.I. Hrovat, PhD., C. Farrar, PhD, D.M. Systrom, MD, Boston, MA
Relationship Between Respiratory Drive and Skeletal Muscle pHi During Exercise by 31PMRS. Am J Respir Crit Care Med. 2006; A2001.
Relationship Between Respiratory Drive and Skeletal Muscle pHi During Exercise by 31PMRS
J.J. Tolle, MD, A.B. Waxman, MD, D.M. Systrom, MD. Massachusetts General Hospital, Harvard Medical School, Boston, MA
Abnormal Systemic O2 Extraction During Incremental Exercise in Pulmonary Arterial Hypertension. Am J Respir Crit Care Med. 2006.
Abnormal Systemic O2 Extraction During Incremental Exercise in Pulmonary Arterial Hypertension
An elevated breathing reserve index at the lactate threshold is a predictor of mortality in patients with cystic fibrosis awaiting lung transplantation. Am J Respir Crit Care Med. 2002 Jun 15; 165(12):1629-33.
An elevated breathing reserve index at the lactate threshold is a predictor of mortality in patients with cystic fibrosis awaiting lung transplantation.
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Disorders of ventilatory control. In: Bradstetter R, ed. Pulmonary medicine: problems in primary care
Systrom DM, Kao A, Sheridan R, Cash S, Ryan E, Ferrara S.
A 17-year old girl with respiratory distress and hemiparesis after survivng a tsunami. N Engl J Med. 2005; 352:2628-36.
A 17-year old girl with respiratory distress and hemiparesis after survivng a tsunami
Diagnosis of pulmonary vascular limit to exercise by cardiopulmonary exercise testing. J Heart Lung Transplant. 2004 Jan; 23(1):88-95.
Diagnosis of pulmonary vascular limit to exercise by cardiopulmonary exercise testing.
Fleischman A, Johnsen S, Systrom DM, Hrovat M, Farrar CT, Frontera W, Fitch K, Thomas BJ, Torriani M, Côté HC, Grinspoon SK
American journal of physiology. Endocrinology and metabolism
Effects of a nucleoside reverse transcriptase inhibitor, stavudine, on glucose disposal and mitochondrial function in muscle of healthy adults. Am J Physiol Endocrinol Metab. 2007 Jun; 292(6):E1666-73.
Effects of a nucleoside reverse transcriptase inhibitor, stavudine, on glucose disposal and mitochondrial function in muscle of healthy adults.
Asthma. In: Fishman, Hoffman, Klausner, Thaler, eds. Medicine. Philadelphia: JB Lippincott Co. 1996; 91-6.
Asthma. In: Fishman, Hoffman, Klausner, Thaler, eds. Medicine. 2004; 97-104.
Kohli P, Kelly VJ, Kehl EG, Rodriguez-Lopez J, Hibbert KA, Kone M, Systrom DM, Waxman AB, Venegas JG, Channick R, Winkler T, Harris RS
Perfusion Imaging Distinguishes Exercise Pulmonary Arterial Hypertension at Rest. Am J Respir Crit Care Med. 2019 06 01; 199(11):1438-1441.
Perfusion Imaging Distinguishes Exercise Pulmonary Arterial Hypertension at Rest.
Harvard T.H. Chan School of Public Health
Singh I, Oliveira RKF, Naeije R, Rahaghi FN, Oldham WM, Systrom DM, Waxman AB
Pulmonary Vascular Distensibility and Early Pulmonary Vascular Remodeling in Pulmonary Hypertension. Chest. 2019 10; 156(4):724-732.
Pulmonary Vascular Distensibility and Early Pulmonary Vascular Remodeling in Pulmonary Hypertension.
Singh I, Rahaghi FN, Naeije R, Oliveira RKF, Systrom DM, Waxman AB
Right Ventricular-Arterial Uncoupling During Exercise in Heart Failure With Preserved Ejection Fraction: Role of Pulmonary Vascular Dysfunction. Chest. 2019 11; 156(5):933-943.
Right Ventricular-Arterial Uncoupling During Exercise in Heart Failure With Preserved Ejection Fraction: Role of Pulmonary Vascular Dysfunction.
Associate Professor of Emergency Medicine
Adjunct Professor of Environmental Health
Singh I, Rahaghi FN, Naeije R, Oliveira RKF, Vanderpool RR, Waxman AB, Systrom DM
Dynamic right ventricular-pulmonary arterial uncoupling during maximum incremental exercise in exercise pulmonary hypertension and pulmonary arterial hypertension. Pulm Circ. 2019 Jul-Sep; 9(3):2045894019862435.
Dynamic right ventricular-pulmonary arterial uncoupling during maximum incremental exercise in exercise pulmonary hypertension and pulmonary arterial hypertension.
Fatigue, Sleep, and Autoimmune and Related Disorders. Front Immunol. 2019; 10:1827.
Fatigue, Sleep, and Autoimmune and Related Disorders.
Melamed KH, Santos M, Oliveira RKF, Urbina MF, Felsenstein D, Opotowsky AR, Waxman AB, Systrom DM
Unexplained exertional intolerance associated with impaired systemic oxygen extraction. Eur J Appl Physiol. 2019 Oct; 119(10):2375-2389.
Unexplained exertional intolerance associated with impaired systemic oxygen extraction.
Sanders JL, Han Y, Urbina MF, Systrom DM, Waxman AB
Metabolomics of exercise pulmonary hypertension are intermediate between controls and patients with pulmonary arterial hypertension. Pulm Circ. 2019 Oct-Dec; 9(4):2045894019882623.
Metabolomics of exercise pulmonary hypertension are intermediate between controls and patients with pulmonary arterial hypertension.
Tang WHW, Wilcox JD, Jacob MS, Rosenzweig EB, Borlaug BA, Frantz RP, Hassoun PM, Hemnes AR, Hill NS, Horn EM, Singh HS, Systrom DM, Tedford RJ, Vanderpool RR, Waxman AB, Xiao L, Leopold JA, Rischard FP
Comprehensive Diagnostic Evaluation of Cardiovascular Physiology in Patients With Pulmonary Vascular Disease: Insights From the PVDOMICS Program. Circ Heart Fail. 2020 03; 13(3):e006363.
Comprehensive Diagnostic Evaluation of Cardiovascular Physiology in Patients With Pulmonary Vascular Disease: Insights From the PVDOMICS Program.
Oliveira RKF, Waxman AB, Hoover PJ, Dellaripa PF, Systrom DM
Pulmonary Vascular and Right Ventricular Burden During Exercise in Interstitial Lung Disease. Chest. 2020 07; 158(1):350-358.
Pulmonary Vascular and Right Ventricular Burden During Exercise in Interstitial Lung Disease.
Joseph P, Oliveira RKF, Eslam RB, Agarwal M, Waxman AB, Systrom DM
Fick principle and exercise pulmonary hemodynamic determinants of the six-minute walk distance in pulmonary hypertension. Pulm Circ. 2020 Jul-Sep; 10(3):2045894020957576.
Fick principle and exercise pulmonary hemodynamic determinants of the six-minute walk distance in pulmonary hypertension.
Singh I, Oliveira RKF, Naeije R, Oldham WM, Faria-Urbina M, Waxman AB, Systrom DM
Systemic vascular distensibility relates to exercise capacity in connective tissue disease. Rheumatology (Oxford). 2021 03 02; 60(3):1429-1434.
Systemic vascular distensibility relates to exercise capacity in connective tissue disease.
Singh I, Oliveira RKF, Heerdt P, Brown MB, Faria-Urbina M, Waxman AB, Systrom DM
Dynamic right ventricular function response to incremental exercise in pulmonary hypertension. Pulm Circ. 2020 Jul-Sep; 10(3):2045894020950187.
Dynamic right ventricular function response to incremental exercise in pulmonary hypertension.
Singh I, Oliveira RKF, Heerdt PM, Pari R, Systrom DM, Waxman AB
Sex-Related Differences in Dynamic Right Ventricular-Pulmonary Vascular Coupling in Heart Failure With Preserved Ejection Fraction. Chest. 2021 06; 159(6):2402-2416.
Sex-Related Differences in Dynamic Right Ventricular-Pulmonary Vascular Coupling in Heart Failure With Preserved Ejection Fraction.
Messina CMS, Ferreira EVM, Singh I, Fonseca AXC, Ramos RP, Nery LE, Systrom DM, Oliveira RKF, Ota-Arakaki JS
Impact of right ventricular work and pulmonary arterial compliance on peak exercise oxygen uptake in idiopathic pulmonary arterial hypertension. Int J Cardiol. 2021 05 15; 331:230-235.
Impact of right ventricular work and pulmonary arterial compliance on peak exercise oxygen uptake in idiopathic pulmonary arterial hypertension.
The Role of Exercise Testing in Pulmonary Vascular Disease: Diagnosis and Management. Clin Chest Med. 2021 03; 42(1):113-123.
The Role of Exercise Testing in Pulmonary Vascular Disease: Diagnosis and Management.
Joseph P, Arevalo C, Oliveira RKF, Faria-Urbina M, Felsenstein D, Oaklander AL, Systrom DM
Insights From Invasive Cardiopulmonary Exercise Testing of Patients With Myalgic Encephalomyelitis/Chronic Fatigue Syndrome. Chest. 2021 08; 160(2):642-651.
Insights From Invasive Cardiopulmonary Exercise Testing of Patients With Myalgic Encephalomyelitis/Chronic Fatigue Syndrome.
Vernino S, Bourne KM, Stiles LE, Grubb BP, Fedorowski A, Stewart JM, Arnold AC, Pace LA, Axelsson J, Boris JR, Moak JP, Goodman BP, Chémali KR, Chung TH, Goldstein DS, Diedrich A, Miglis MG, Cortez MM, Miller AJ, Freeman R, Biaggioni I, Rowe PC, Sheldon RS, Shibao CA, Systrom DM, Cook GA, Doherty TA, Abdallah HI, Darbari A, Raj SR
Autonomic neuroscience : basic & clinical
Postural orthostatic tachycardia syndrome (POTS): State of the science and clinical care from a 2019 National Institutes of Health Expert Consensus Meeting - Part 1. Auton Neurosci. 2021 11; 235:102828.
Postural orthostatic tachycardia syndrome (POTS): State of the science and clinical care from a 2019 National Institutes of Health Expert Consensus Meeting - Part 1.
Raj SR, Bourne KM, Stiles LE, Miglis MG, Cortez MM, Miller AJ, Freeman R, Biaggioni I, Rowe PC, Sheldon RS, Shibao CA, Diedrich A, Systrom DM, Cook GA, Doherty TA, Abdallah HI, Grubb BP, Fedorowski A, Stewart JM, Arnold AC, Pace LA, Axelsson J, Boris JR, Moak JP, Goodman BP, Chémali KR, Chung TH, Goldstein DS, Darbari A, Vernino S
Postural orthostatic tachycardia syndrome (POTS): Priorities for POTS care and research from a 2019 National Institutes of Health Expert Consensus Meeting - Part 2. Auton Neurosci. 2021 11; 235:102836.
Postural orthostatic tachycardia syndrome (POTS): Priorities for POTS care and research from a 2019 National Institutes of Health Expert Consensus Meeting - Part 2.
Singh I, Joseph P, Heerdt PM, Cullinan M, Lutchmansingh DD, Gulati M, Possick JD, Systrom DM, Waxman AB
Persistent Exertional Intolerance After COVID-19: Insights From Invasive Cardiopulmonary Exercise Testing. Chest. 2022 01; 161(1):54-63.
Persistent Exertional Intolerance After COVID-19: Insights From Invasive Cardiopulmonary Exercise Testing.
Yazdi D, Sridaran S, Smith S, Centen C, Patel S, Wilson E, Gillon L, Kapur S, Tracy JA, Lewine K, Systrom DM, MacRae CA
Journal of the American Heart Association
Noninvasive Scale Measurement of Stroke Volume and Cardiac Output Compared With the Direct Fick Method: A Feasibility Study. J Am Heart Assoc. 2021 12 21; 10(24):e021893.
Noninvasive Scale Measurement of Stroke Volume and Cardiac Output Compared With the Direct Fick Method: A Feasibility Study.
Novak P, Mukerji SS, Alabsi HS, Systrom D, Marciano SP, Felsenstein D, Mullally WJ, Pilgrim DM
Multisystem Involvement in Post-Acute Sequelae of Coronavirus Disease 19. Ann Neurol. 2022 03; 91(3):367-379.
Multisystem Involvement in Post-Acute Sequelae of Coronavirus Disease 19.
Joseph P, Pari R, Miller S, Warren A, Stovall MC, Squires J, Chang CJ, Xiao W, Waxman AB, Systrom DM
Neurovascular Dysregulation and Acute Exercise Intolerance in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: A Randomized, Placebo-Controlled Trial of Pyridostigmine. Chest. 2022 11; 162(5):1116-1126.
Neurovascular Dysregulation and Acute Exercise Intolerance in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: A Randomized, Placebo-Controlled Trial of Pyridostigmine.
Rao P, Peritz DC, Systrom D, Lewine K, Cornwell WK, Hsu JJ
Orthostatic and Exercise Intolerance in Recreational and Competitive Athletes With Long COVID. JACC Case Rep. 2022 Sep 07; 4(17):1119-1123.
Orthostatic and Exercise Intolerance in Recreational and Competitive Athletes With Long COVID.
Novak P, Giannetti MP, Weller E, Hamilton MJ, Mukerji SS, Alabsi HS, Systrom D, Marciano SP, Felsenstein D, Mullally WJ, Pilgrim DM, Castells M
Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology
Network autonomic analysis of post-acute sequelae of COVID-19 and postural tachycardia syndrome. Neurol Sci. 2022 Dec; 43(12):6627-6638.
Network autonomic analysis of post-acute sequelae of COVID-19 and postural tachycardia syndrome.
Winkler T, Kohli P, Kelly VJ, Kehl EG, Witkin AS, Rodriguez-Lopez JM, Hibbert KA, Kone MT, Systrom DM, Waxman AB, Venegas JG, Channick RN, Harris RS
Perfusion imaging heterogeneity during NO inhalation distinguishes pulmonary arterial hypertension (PAH) from healthy subjects and has potential as an imaging biomarker. Respir Res. 2022 Dec 01; 23(1):325.
Perfusion imaging heterogeneity during NO inhalation distinguishes pulmonary arterial hypertension (PAH) from healthy subjects and has potential as an imaging biomarker.
Hammerness P, Zusman R, Systrom D, Surman C, Baggish A, Schillinger M, Shelley-Abrahamson R, Wilens TE
The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry
A cardiopulmonary study of lisdexamfetamine in adults with attention-deficit/hyperactivity disorder. World J Biol Psychiatry. 2013 May; 14(4):299-306.
A cardiopulmonary study of lisdexamfetamine in adults with attention-deficit/hyperactivity disorder.
Joseph P, Singh I, Oliveira R, Capone CA, Mullen MP, Cook DB, Stovall MC, Squires J, Madsen K, Waxman AB, Systrom DM
Exercise Pathophysiology in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome and Postacute Sequelae of SARS-CoV-2: More in Common Than Not? Chest. 2023 09; 164(3):717-726.
Exercise Pathophysiology in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome and Postacute Sequelae of SARS-CoV-2: More in Common Than Not?
Slavin MD, Bailey HM, Hickey EJ, Vasudevan A, Ledingham A, Tannenbaum L, Bateman L, Kaufman DL, Peterson DL, Ruhoy IS, Systrom DM, Felsenstein D, Kazis LE
Myalgic Encephalomyelitis-Chronic Fatigue Syndrome Common Data Element item content analysis. PLoS One. 2023; 18(9):e0291364.
Myalgic Encephalomyelitis-Chronic Fatigue Syndrome Common Data Element item content analysis.
Khurshid S, Churchill TW, Diamant N, Di Achille P, Reeder C, Singh P, Friedman SF, Wasfy MM, Alba GA, Maron BA, Systrom DM, Wertheim BM, Ellinor PT, Ho JE, Baggish AL, Batra P, Lubitz SA, Guseh JS
European journal of preventive cardiology
Deep learned representations of the resting 12-lead electrocardiogram to predict at peak exercise. Eur J Prev Cardiol. 2024 Jan 25; 31(2):252-262.
Deep learned representations of the resting 12-lead electrocardiogram to predict at peak exercise.
Novak P, Systrom DM, Marciano SP, Knief A, Felsenstein D, Giannetti MP, Hamilton MJ, Nicoloro-SantaBarbara J, Saco TV, Castells M, Farhad K, Pilgrim DM, Mullally WJ
Mismatch between subjective and objective dysautonomia. Sci Rep. 2024 01 30; 14(1):2513.
Mismatch between subjective and objective dysautonomia.
Waxman AB, Systrom DM, Manimaran S, de Oliveira Pena J, Lu J, Rischard FP
SPECTRA Phase 2b Study: Impact of Sotatercept on Exercise Tolerance and Right Ventricular Function in Pulmonary Arterial Hypertension. Circ Heart Fail. 2024 May; 17(5):e011227.
SPECTRA Phase 2b Study: Impact of Sotatercept on Exercise Tolerance and Right Ventricular Function in Pulmonary Arterial Hypertension.
Pulmonary congestion in patients with pulmonary arterial hypertension? New insights from lung ultrasound. Eur J Heart Fail. 2024 Apr; 26(4):825-828.
Pulmonary congestion in patients with pulmonary arterial hypertension? New insights from lung ultrasound.
Kovacs G, Humbert M, Avian A, Lewis GD, Ulrich S, Vonk Noordegraaf A, Souza R, Galiè N, Malhotra R, Saxer S, Grünig E, Egenlauf B, Ewert R, Heine A, Tedford RJ, Houston BA, Kasperowicz K, Kurzyna M, Rosenkranz S, Herkenrath S, Barbera JA, Blanco I, Oliveira RKF, Andersen M, Savale L, Systrom D, Maron BA, Tello K, Condliffe R, Mak S, Baratto C, Hsu S, D'Alto M, McCabe C, Herve P, Olschewski H
Prognostic relevance of exercise pulmonary hypertension: results of the multicentre PEX-NET Clinical Research Collaboration. Eur Respir J. 2024 Dec; 64(6).
Prognostic relevance of exercise pulmonary hypertension: results of the multicentre PEX-NET Clinical Research Collaboration.
Novak P, Systrom DM, Witte A, Marciano SP
Orthostatic intolerance with tachycardia (postural tachycardia syndrome) and without (hypocapnic cerebral hypoperfusion) represent a spectrum of the same disorder. Front Neurol. 2024; 15:1476918.
Orthostatic intolerance with tachycardia (postural tachycardia syndrome) and without (hypocapnic cerebral hypoperfusion) represent a spectrum of the same disorder.
Harder EM, Rahaghi FN, Leopold JA, Systrom DM, Washko GR, Waxman AB
Vasoreactivity and inhaled treprostinil response in interstitial lung disease pulmonary hypertension. ERJ Open Res. 2024 Nov; 10(6).
Vasoreactivity and inhaled treprostinil response in interstitial lung disease pulmonary hypertension.
Novak P, Systrom DM, Marciano SP, Witte A, Warren A, Felsenstein D, Giannetti MP, Hamilton MJ, Nicoloro-SantaBarbara J, Castells M, Farhad K, Pilgrim DM, Mullally WJ, Fishman MC, Milunsky JM, Milunsky A, Krier J
Hypermobile Ehlers-Danlos Syndrome: Cerebrovascular, Autonomic and Neuropathic Features. Am J Med Open. 2025 Dec; 14:100111.
Hypermobile Ehlers-Danlos Syndrome: Cerebrovascular, Autonomic and Neuropathic Features.
Boerrigter BG, Waxman AB, Westerhof N, Vonk-Noordegraaf A, Systrom DM
Measuring central pulmonary pressures during exercise in COPD: how to cope with respiratory effects. Eur Respir J. 2014 May; 43(5):1316-25.
Measuring central pulmonary pressures during exercise in COPD: how to cope with respiratory effects.
Chowdhury MA, Squires J, Systrom DM, Waxman AB
Impact of patient positioning on hemodynamic assessment: A comparison of supine and upright right heart catheterization. Physiol Rep. 2025 Oct; 13(20):e70632.
Impact of patient positioning on hemodynamic assessment: A comparison of supine and upright right heart catheterization.
Ghanbari F, Rodriguez J, Morales MA, Ngo LH, Tsao CW, Robbins JM, Gopal DM, Systrom DM, Waxman AB, Manning WJ, Nezafat R
Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance
Exercise cardiovascular magnetic resonance myocardial dynamic index: A non-invasive imaging marker associated with cardiac dyspnea. J Cardiovasc Magn Reson. 2025 Winter; 27(2):101981.
Exercise cardiovascular magnetic resonance myocardial dynamic index: A non-invasive imaging marker associated with cardiac dyspnea.
Novak P, Systrom DM, Witte A, Marciano SP, Felsenstein D, Milunsky JM, Milunsky A, Krier J, Fishman MC
Shared autonomic phenotype of long COVID and myalgic encephalomyelitis/chronic fatigue syndrome. PLoS One. 2026; 21(1):e0341278.
Shared autonomic phenotype of long COVID and myalgic encephalomyelitis/chronic fatigue syndrome.
Charlton BT, Janssen K, Systrom DM, Putrino D, Wüst RC
Post-exertional malaise and the myth of cardiac deconditioning: rethinking the pathophysiology of long covid. Br J Sports Med. 2026 Mar 31; 60(8):600-601.
Post-exertional malaise and the myth of cardiac deconditioning: rethinking the pathophysiology of long covid.
Waxman AB, Babu A, Badagliacca R, Ferreira E, George P, Guazzi M, Howard L, Kim D, Kovacs G, Kubba S, Langleben D, McCabe C, Menezes T, Oliveira R, Orfanos S, Singh I, Systrom D, Tedford R, Vanderpool R, Vizza CD, Rischard FP
Knowledge Gaps and Controversies on Cardiopulmonary Exercise Testing in the Assessment of Pulmonary Vascular Disease: An Official Statement of the Pulmonary Vascular Research Institute Exercise and Right Ventricular Function Task Force. Pulm Circ. 2026 Jan; 16(1):e70240.
Knowledge Gaps and Controversies on Cardiopulmonary Exercise Testing in the Assessment of Pulmonary Vascular Disease: An Official Statement of the Pulmonary Vascular Research Institute Exercise and Right Ventricular Function Task Force.
Opotowsky AR, Landzberg MJ, Earing MG, Wu FM, Triedman JK, Casey A, Ericson DA, Systrom D, Paridon SM, Rhodes J
American journal of physiology. Heart and circulatory physiology
Abnormal spirometry after the Fontan procedure is common and associated with impaired aerobic capacity. Am J Physiol Heart Circ Physiol. 2014 Jul 01; 307(1):H110-7.
Abnormal spirometry after the Fontan procedure is common and associated with impaired aerobic capacity.
McCormack SE, McCarthy MA, Harrington SG, Farilla L, Hrovat MI, Systrom DM, Thomas BJ, Torriani M, McInnis K, Grinspoon SK, Fleischman A
Effects of exercise and lifestyle modification on fitness, insulin resistance, skeletal muscle oxidative phosphorylation and intramyocellular lipid content in obese children and adolescents. Pediatr Obes. 2014 Aug; 9(4):281-91.
Effects of exercise and lifestyle modification on fitness, insulin resistance, skeletal muscle oxidative phosphorylation and intramyocellular lipid content in obese children and adolescents.
Opotowsky AR, Halpern D, Kulik TJ, Systrom DM, Wu F
Inadequate venous return as a primary cause for Fontan circulatory limitation. J Heart Lung Transplant. 2014 Nov; 33(11):1194-6.
Inadequate venous return as a primary cause for Fontan circulatory limitation.
Santos M, Systrom D, Epstein SE, John A, Ruiz G, Landzberg MJ, Opotowsky AR
Impaired exercise capacity following atrial septal defect closure: an invasive study of the right heart and pulmonary circulation. Pulm Circ. 2014 Dec; 4(4):630-7.
Impaired exercise capacity following atrial septal defect closure: an invasive study of the right heart and pulmonary circulation.
Nathan AS, Loukas B, Moko L, Wu F, Rhodes J, Rathod RH, Systrom DM, Ubeda Tikkanen A, Shafer K, Lewis GD, Landzberg MJ, Opotowsky AR
Exercise oscillatory ventilation in patients with Fontan physiology. Circ Heart Fail. 2015 Mar; 8(2):304-11.
Exercise oscillatory ventilation in patients with Fontan physiology.
Santos M, Opotowsky AR, Shah AM, Tracy J, Waxman AB, Systrom DM
Central cardiac limit to aerobic capacity in patients with exertional pulmonary venous hypertension: implications for heart failure with preserved ejection fraction. Circ Heart Fail. 2015 Mar; 8(2):278-85.
Central cardiac limit to aerobic capacity in patients with exertional pulmonary venous hypertension: implications for heart failure with preserved ejection fraction.
White K, Lu Y, Annis S, Hale AE, Chau BN, Dahlman JE, Hemann C, Opotowsky AR, Vargas SO, Rosas I, Perrella MA, Osorio JC, Haley KJ, Graham BB, Kumar R, Saggar R, Saggar R, Wallace WD, Ross DJ, Khan OF, Bader A, Gochuico BR, Matar M, Polach K, Johannessen NM, Prosser HM, Anderson DG, Langer R, Zweier JL, Bindoff LA, Systrom D, Waxman AB, Jin RC, Chan SY
Genetic and hypoxic alterations of the microRNA-210-ISCU1/2 axis promote iron-sulfur deficiency and pulmonary hypertension. EMBO Mol Med. 2015 Jun; 7(6):695-713.
Genetic and hypoxic alterations of the microRNA-210-ISCU1/2 axis promote iron-sulfur deficiency and pulmonary hypertension.
Santos M, Rivero J, McCullough SD, West E, Opotowsky AR, Waxman AB, Systrom DM, Shah AM
E/e' Ratio in Patients With Unexplained Dyspnea: Lack of Accuracy in Estimating Left Ventricular Filling Pressure. Circ Heart Fail. 2015 Jul; 8(4):749-56.
E/e' Ratio in Patients With Unexplained Dyspnea: Lack of Accuracy in Estimating Left Ventricular Filling Pressure.
Oliveira RK, Agarwal M, Tracy JA, Karin AL, Opotowsky AR, Waxman AB, Systrom DM
Age-related upper limits of normal for maximum upright exercise pulmonary haemodynamics. Eur Respir J. 2016 Apr; 47(4):1179-88.
Age-related upper limits of normal for maximum upright exercise pulmonary haemodynamics.
Berry NC, Manyoo A, Oldham WM, Stephens TE, Goldstein RH, Waxman AB, Tracy JA, Leary PJ, Leopold JA, Kinlay S, Opotowsky AR, Systrom DM, Maron BA
Protocol for exercise hemodynamic assessment: performing an invasive cardiopulmonary exercise test in clinical practice. Pulm Circ. 2015 Dec; 5(4):610-8.
Protocol for exercise hemodynamic assessment: performing an invasive cardiopulmonary exercise test in clinical practice.
Oldham WM, Lewis GD, Opotowsky AR, Waxman AB, Systrom DM
Unexplained exertional dyspnea caused by low ventricular filling pressures: results from clinical invasive cardiopulmonary exercise testing. Pulm Circ. 2016 Mar; 6(1):55-62.
Unexplained exertional dyspnea caused by low ventricular filling pressures: results from clinical invasive cardiopulmonary exercise testing.
Oliveira RK, Waxman AB, Agarwal M, Badr Eslam R, Systrom DM
Pulmonary haemodynamics during recovery from maximum incremental cycling exercise. Eur Respir J. 2016 07; 48(1):158-67.
Pulmonary haemodynamics during recovery from maximum incremental cycling exercise.
Dyspnea and an Arteriovenous Fistula. Ann Am Thorac Soc. 2016 Aug; 13(8):1419-23.
Biering-Sørensen T, Santos M, Rivero J, McCullough SD, West E, Opotowsky AR, Waxman AB, Systrom DM, Shah AM
Left ventricular deformation at rest predicts exercise-induced elevation in pulmonary artery wedge pressure in patients with unexplained dyspnoea. Eur J Heart Fail. 2017 01; 19(1):101-110.
Left ventricular deformation at rest predicts exercise-induced elevation in pulmonary artery wedge pressure in patients with unexplained dyspnoea.
van Riel AC, Systrom DM, Oliveira RK, Landzberg MJ, Mulder BJ, Bouma BJ, Maron BA, Shah AM, Waxman AB, Opotowsky AR
Journal of the American College of Cardiology
Development of a Right Ventricular Outflow Tract Gradient During Upright Exercise: A Hemodynamic Observation. J Am Coll Cardiol. 2017 02 07; 69(5):595-597.
Development of a Right Ventricular Outflow Tract Gradient During Upright Exercise: A Hemodynamic Observation.
Systrom DM, Pappagianopoulos P, Fishman RS, Wain JC, Ginns LC
Determinants of abnormal maximum oxygen uptake after lung transplantation for chronic obstructive pulmonary disease. J Heart Lung Transplant. 1998 Dec; 17(12):1220-30.
Determinants of abnormal maximum oxygen uptake after lung transplantation for chronic obstructive pulmonary disease.
Carbon dioxide pressure-concentration relationship in arterial and mixed venous blood. J Appl Physiol (1985). 2001 Nov; 91(5):2413; author reply 2413-4.
Carbon dioxide pressure-concentration relationship in arterial and mixed venous blood.
Systrom DM, Hrovat M, Oelberg D, Kazemi H
Advances in experimental medicine and biology
Skeletal muscle chemoreflex in exercise ventilatory control. Adv Exp Med Biol. 2001; 499:343-8.
Skeletal muscle chemoreflex in exercise ventilatory control.
Medoff BD, Oelberg DA, Kanarek DJ, Systrom DM
Breathing reserve at the lactate threshold to differentiate a pulmonary mechanical from cardiovascular limit to exercise. Chest. 1998 Apr; 113(4):913-8.
Breathing reserve at the lactate threshold to differentiate a pulmonary mechanical from cardiovascular limit to exercise.
Tikkanen AU, Rhodes J, Landzberg M, Bhatt A, Systrom DM, Waxman A, Moko L, Bradley R, Crouter S, Opotowsky A
PM & R : the journal of injury, function, and rehabilitation
Poster 26 A Randomized Trial of Cardiac Rehabilitation for Adolescents and Adults with Congenital Heart Disease. PM R. 2016 Sep; 8(9S):S169.
Poster 26 A Randomized Trial of Cardiac Rehabilitation for Adolescents and Adults with Congenital Heart Disease.
Andreu AL, Bruno C, Shanske S, Shtilbans A, Hirano M, Krishna S, Hayward L, Systrom DS, Brown RH, DiMauro S
Missense mutation in the mtDNA cytochrome b gene in a patient with myopathy. Neurology. 1998 Nov; 51(5):1444-7.
Missense mutation in the mtDNA cytochrome b gene in a patient with myopathy.
Systrom DM, Fragoso CV, Kanarek DJ, Kazemi H
Ammonium ion and the anaerobic threshold in man. Chest. 1991 May; 99(5):1197-202.
Ammonium ion and the anaerobic threshold in man.
Evans AB, Al-Himyary AJ, Hrovat MI, Pappagianopoulos P, Wain JC, Ginns LC, Systrom DM
Abnormal skeletal muscle oxidative capacity after lung transplantation by 31P-MRS. Am J Respir Crit Care Med. 1997 Feb; 155(2):615-21.
Abnormal skeletal muscle oxidative capacity after lung transplantation by 31P-MRS.
Oelberg DA, Medoff BD, Markowitz DH, Pappagianopoulos PP, Ginns LC, Systrom DM
European journal of applied physiology and occupational physiology
Systemic oxygen extraction during incremental exercise in patients with severe chronic obstructive pulmonary disease. Eur J Appl Physiol Occup Physiol. 1998 Aug; 78(3):201-7.
Systemic oxygen extraction during incremental exercise in patients with severe chronic obstructive pulmonary disease.
van Riel AC, Opotowsky AR, Santos M, Rivero JM, Dhimitri A, Mulder BJ, Bouma BJ, Landzberg MJ, Waxman AB, Systrom DM, Shah AM
Accuracy of Echocardiography to Estimate Pulmonary Artery Pressures With Exercise: A Simultaneous Invasive-Noninvasive Comparison. Circ Cardiovasc Imaging. 2017 Apr; 10(4).
Accuracy of Echocardiography to Estimate Pulmonary Artery Pressures With Exercise: A Simultaneous Invasive-Noninvasive Comparison.
Journal of cardiothoracic and vascular anesthesia
Preoperative cardiopulmonary exercise testing: determining the limit to exercise and predicting outcome after thoracotomy. J Cardiothorac Vasc Anesth. 1991 Dec; 5(6):614-26.
Preoperative cardiopulmonary exercise testing: determining the limit to exercise and predicting outcome after thoracotomy.
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Improvement in exercise capacity after nocturnal positive pressure ventilation and tracheostomy in a postpoliomyelitis patient. Chest. 1992 Jan; 101(1):254-7.
Improvement in exercise capacity after nocturnal positive pressure ventilation and tracheostomy in a postpoliomyelitis patient.
Huang W, Resch S, Oliveira RK, Cockrill BA, Systrom DM, Waxman AB
Invasive cardiopulmonary exercise testing in the evaluation of unexplained dyspnea: Insights from a multidisciplinary dyspnea center. Eur J Prev Cardiol. 2017 07; 24(11):1190-1199.
Invasive cardiopulmonary exercise testing in the evaluation of unexplained dyspnea: Insights from a multidisciplinary dyspnea center.
Oelberg DA, Evans AB, Hrovat MI, Pappagianopoulos PP, Patz S, Systrom DM
Skeletal muscle chemoreflex and pHi in exercise ventilatory control. J Appl Physiol (1985). 1998 Feb; 84(2):676-82.
Skeletal muscle chemoreflex and pHi in exercise ventilatory control.
Fleischman A, Kron M, Systrom DM, Hrovat M, Grinspoon SK
Mitochondrial function and insulin resistance in overweight and normal-weight children. J Clin Endocrinol Metab. 2009 Dec; 94(12):4923-30.
Mitochondrial function and insulin resistance in overweight and normal-weight children.
Segrera SA, Lawler L, Opotowsky AR, Systrom D, Waxman AB
Open label study of ambrisentan in patients with exercise pulmonary hypertension. Pulm Circ. 2017 Apr-Jun; 7(2):531-538.
Open label study of ambrisentan in patients with exercise pulmonary hypertension.
Smoller JW, Pollack MH, Systrom D, Kradin RL
Sertraline effects on dyspnea in patients with obstructive airways disease. Psychosomatics. 1998 Jan-Feb; 39(1):24-9.
Sertraline effects on dyspnea in patients with obstructive airways disease.
van Riel ACMJ, Systrom DM, Oliveira RKF, Landzberg MJ, Mulder BJM, Bouma BJ, Maron BA, Shah AM, Waxman AB, Opotowsky AR
Hemodynamic and metabolic characteristics associated with development of a right ventricular outflow tract pressure gradient during upright exercise. PLoS One. 2017; 12(6):e0179053.
Hemodynamic and metabolic characteristics associated with development of a right ventricular outflow tract pressure gradient during upright exercise.
Systrom DM, Kanarek DJ, Kohler SJ, Kazemi H
31P nuclear magnetic resonance spectroscopy study of the anaerobic threshold in humans. J Appl Physiol (1985). 1990 May; 68(5):2060-6.
31P nuclear magnetic resonance spectroscopy study of the anaerobic threshold in humans.
Makimura H, Stanley TL, Sun N, Hrovat MI, Systrom DM, Grinspoon SK
The association of growth hormone parameters with skeletal muscle phosphocreatine recovery in adult men. J Clin Endocrinol Metab. 2011 Mar; 96(3):817-23.
The association of growth hormone parameters with skeletal muscle phosphocreatine recovery in adult men.
Skeletal Muscle Ventilatory Chemoreflex during Exercise with Repetitive Partial Circulatory Occlusion. Am J Respir Crit Care Med. 2007; 175:4396.
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Lewis GD, Shah RV, Pappagianopolas PP, Systrom DM, Semigran MJ
Determinants of ventilatory efficiency in heart failure: the role of right ventricular performance and pulmonary vascular tone. Circ Heart Fail. 2008 Nov; 1(4):227-33.
Determinants of ventilatory efficiency in heart failure: the role of right ventricular performance and pulmonary vascular tone.
McCormack SE, McCarthy MA, Farilla L, Hrovat MI, Systrom DM, Grinspoon SK, Fleischman A
Skeletal muscle mitochondrial function is associated with longitudinal growth velocity in children and adolescents. J Clin Endocrinol Metab. 2011 Oct; 96(10):E1612-8.
Skeletal muscle mitochondrial function is associated with longitudinal growth velocity in children and adolescents.
Central respiratory effects of glutamine synthesis inhibition in dogs. J Appl Physiol (1985). 1988 Sep; 65(3):1099-109.
Central respiratory effects of glutamine synthesis inhibition in dogs.
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Skeletal muscle chemoreflex in exercise ventilatory control
Case records of the Massachusetts General Hospital. N Engl J Med. 1995; 332:1700-7.
Spengler CM, Banzett RB, Systrom DM, Shannon DC, Shea SA
Respiratory sensations during heavy exercise in subjects without respiratory chemosensitivity. Respir Physiol. 1998 Oct; 114(1):65-74.
Respiratory sensations during heavy exercise in subjects without respiratory chemosensitivity.
Oliveira RKF, Faria-Urbina M, Maron BA, Santos M, Waxman AB, Systrom DM
Functional impact of exercise pulmonary hypertension in patients with borderline resting pulmonary arterial pressure. Pulm Circ. 2017 Jul-Sep; 7(3):654-665.
Functional impact of exercise pulmonary hypertension in patients with borderline resting pulmonary arterial pressure.
Guazzi M, Bandera F, Ozemek C, Systrom D, Arena R
Cardiopulmonary Exercise Testing: What Is its Value? J Am Coll Cardiol. 2017 Sep 26; 70(13):1618-1636.
Cardiopulmonary Exercise Testing: What Is its Value?
Makimura H, Stanley TL, Sun N, Connelly JM, Hemphill LC, Hrovat MI, Systrom DM, Grinspoon SK
Increased skeletal muscle phosphocreatine recovery after sub-maximal exercise is associated with increased carotid intima-media thickness. Atherosclerosis. 2011 Mar; 215(1):214-7.
Increased skeletal muscle phosphocreatine recovery after sub-maximal exercise is associated with increased carotid intima-media thickness.
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Hemoptysis. In: Fishman, Hoffman, Klausner Thaler, eds. Medicine. Philadelphia: JB Lippincott Co. 1996; 83-5.
Non-invasively measured cardiac output augmentation predicts prognosis in advanced heart failure. Submitted. 2004.
Non-invasively measured cardiac output augmentation predicts prognosis in advanced heart failure
Hemnes AR, Beck GJ, Newman JH, Abidov A, Aldred MA, Barnard J, Berman Rosenzweig E, Borlaug BA, Chung WK, Comhair SAA, Erzurum SC, Frantz RP, Gray MP, Grunig G, Hassoun PM, Hill NS, Horn EM, Hu B, Lempel JK, Maron BA, Mathai SC, Olman MA, Rischard FP, Systrom DM, Tang WHW, Waxman AB, Xiao L, Yuan JX, Leopold JA
PVDOMICS: A Multi-Center Study to Improve Understanding of Pulmonary Vascular Disease Through Phenomics. Circ Res. 2017 10 27; 121(10):1136-1139.
PVDOMICS: A Multi-Center Study to Improve Understanding of Pulmonary Vascular Disease Through Phenomics.
Baggish AL, Hale A, Weiner RB, Lewis GD, Systrom D, Wang F, Wang TJ, Chan SY
Dynamic regulation of circulating microRNA during acute exhaustive exercise and sustained aerobic exercise training. J Physiol. 2011 Aug 15; 589(Pt 16):3983-94.
Dynamic regulation of circulating microRNA during acute exhaustive exercise and sustained aerobic exercise training.
Skeletal muscle dysfunction in chronic obstructive pulmonary disease. Am J Respir Crit Care Med. 1999; 159:S1-S40.
Skeletal muscle dysfunction in chronic obstructive pulmonary disease
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Case Records of the Massachusetts General Hospital. N Engl J Med. 1989; 321:375-85.
LaRaia AV, Lewis GD, Pappagianopoulos PP, Hrovat MI, Farrar C, Systrom DM
Relationship between Respiratory Drive and Skeletal Muscle pHi during Exercise by 31PMRS. Am J Respir Crit Care Med. 2006; A200.
Relationship between Respiratory Drive and Skeletal Muscle pHi during Exercise by 31PMRS
Pulmonary function tests. In; Fishman, Hoffman, Klausner Thaler, eds. Medicine. 4th ed. Philadelphia: JB Lippincpott Co. 1996; 87-9.
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Huang W, Oliveira RKF, Lei H, Systrom DM, Waxman AB
Pulmonary Vascular Resistance During Exercise Predicts Long-Term Outcomes in Heart Failure With Preserved Ejection Fraction. J Card Fail. 2018 Mar; 24(3):169-176.
Pulmonary Vascular Resistance During Exercise Predicts Long-Term Outcomes in Heart Failure With Preserved Ejection Fraction.
Saggar R, Lewis GD, Systrom DM, Champion HC, Naeije R, Saggar R
Pulmonary vascular responses to exercise: a haemodynamic observation. Eur Respir J. 2012 Feb; 39(2):231-4.
Pulmonary vascular responses to exercise: a haemodynamic observation.
Medicine and science in sports and exercise
Impaired systemic oxygen extraction at maximum exercise in pulmonary hypertension. Med Sci Sports Exerc. 2008 Jan; 40(1):3-8.
Impaired systemic oxygen extraction at maximum exercise in pulmonary hypertension.
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Deep vein thrombosis and pulmonary thromboembolism. In: Fishman, Hoffman, Klausner, Thaler, eds. Medicine. Philadlephia: JB Lippincott Co. 1996; 109-15.
Blumenstock DA, Systrom D, Hales C, Alpern H, Kazemi H
Pulmonary function of haplotype-matched and mismatched allografts in dogs treated with total-body irradiation, autologous marrow transplantation, methotrexate, and donor blood. Transplantation. 1988 Oct; 46(4):496-501.
Pulmonary function of haplotype-matched and mismatched allografts in dogs treated with total-body irradiation, autologous marrow transplantation, methotrexate, and donor blood.
Lweis GD, Shin J, Systrom DM, Bloch KD, Semigran MJ
The emerging role of PDE5 inhibition in heart failure. BMC Pharmacology. 2007; 7:S10.
The emerging role of PDE5 inhibition in heart failure
Faria-Urbina M, Oliveira RKF, Segrera SA, Lawler L, Waxman AB, Systrom DM
Impaired systemic oxygen extraction in treated exercise pulmonary hypertension: a new engine in an old car? Pulm Circ. 2018 Jan-Mar; 8(1):2045893218755325.
Impaired systemic oxygen extraction in treated exercise pulmonary hypertension: a new engine in an old car?
Fleischman A, Johnsen S, Systrom DM, Hrovat H. Farrar C. Frontera W, Fitch K. Thomas BJ, Torriani M, Cote HCF, Grinspoon SK.
Alterations in Insulin Sensitivity and Mitochondria by a Nucleoside Reverse Transcriptase Inhibitor in Healthy Adults. Am J Physiol. 2007; 292(6):E1666-73.
Alterations in Insulin Sensitivity and Mitochondria by a Nucleoside Reverse Transcriptase Inhibitor in Healthy Adults
Lung abcess: pathogenesis, diagnosis and treatment. Curr Clin Tpo Infect Dis. 1998; 18:252-73.
Lung abcess: pathogenesis, diagnosis and treatment
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D.A. Oelberg, MD, A.L. Abraham, MD, D.L. Prisco, MD, P.M. DiLauro, RN, J.J. Chronakos, MD, D.M. Systrom, MD, Danbury, CT, Boston, MA
Improved Exercise Performance in Patients With COPD Using Partially Ischemic Leg Training. Am J Respir Crit Care Med. 2006; A220.
Improved Exercise Performance in Patients With COPD Using Partially Ischemic Leg Training
A man with acute respiratory failure. N Engl J Med. 2005; 352:1238-46.
Asthma Critical Pathway. Guidelines for in patient asthma management and treatment at MGH. Commissioned by MGH Medical Administration. Utilized throughout MGH. 1997.
Asthma Critical Pathway. Guidelines for in patient asthma management and treatment at MGH. Commissioned by MGH Medical Administration. Utilized throughout MGH
Ventilatory control and skeletal muscle pHi during recovery from exercise in the human. 2007; Submitted.
A man with acute respiratory failure. N Engl J Med. 2005; 1238-46.
Non-invasively measured cardiac output augmentation predicts prognosis in advanced heart failure. 2007; Submitted.
Current clinical topics in infectious diseases
Lung abscess: pathogenesis, diagnosis and treatment. Curr Clin Top Infect Dis. 1998; 18:252-73.
Lung abscess: pathogenesis, diagnosis and treatment.
Oelberg DA, Kacmarek RM, Pappagianopoulos PP, Ginns LC, Systrom DM
Ventilatory and cardiovascular responses to inspired He-O2 during exercise in chronic obstructive pulmonary disease. Am J Respir Crit Care Med. 1998 Dec; 158(6):1876-82.
Ventilatory and cardiovascular responses to inspired He-O2 during exercise in chronic obstructive pulmonary disease.
Szekely LA, Oelberg DA, Wright C, Johnson DC, Wain J, Trotman-Dickenson B, Shepard JA, Kanarek DJ, Systrom D, Ginns LC
Preoperative predictors of operative morbidity and mortality in COPD patients undergoing bilateral lung volume reduction surgery. Chest. 1997 Mar; 111(3):550-8.
Preoperative predictors of operative morbidity and mortality in COPD patients undergoing bilateral lung volume reduction surgery.
The role of the DLCO in monitoring alveolar proteinosis. J Respir Dis. 1990; 11:671.
The role of the DLCO in monitoring alveolar proteinosis
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