Gilbert, Gary
eCommons Login: GEG1
first name: Gary
last name: Gilbert
coauthor of: Sage, Peter
coauthor of: Lutskiy, Maxim
coauthor of: Wagner, Denisa
full name: Gary Eugene Gilbert, M.D.
has faculty rank: Associate Professor
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person in primary position: Associate Professor of Medicine
similar to: Ewenstein, Bruce
similar to: Croteau, Stacy
similar to: Stowell, Sean
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similar to: Springer, Timothy
type: Agent
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selected publications: Authorship 1669826
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selected publications: Authorship 1070968
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selected publications: Authorship 448895
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selected publications: Authorship 152122
selected publications: Authorship 239109
selected publications: Authorship 594864
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selected publications: Authorship 109834
selected publications: Authorship 143139
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selected publications: Authorship 451795
selected publications: Authorship 527275
selected publications: Authorship 32464
selected publications: Authorship 33903
selected publications: Authorship 88116
selected publications: Authorship 380201
selected publications: Authorship 52021
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selected publications: Authorship 361362
selected publications: Authorship 152297

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Unsaturated phospholipid acyl chains are required to constitute membrane binding sites for factor VIII.
PubMed Identifier: 9753438
author list: Gilbert GE, Arena AA
published in: Biochemistry
information resource reference: Unsaturated phospholipid acyl chains are required to constitute membrane binding sites for factor VIII. Biochemistry. 1998 Sep 29; 37(39):13526-35.
journal title abbreviation: Biochemistry
publication date: 1998-09-29T00:00:00
year: 1998
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1045259
type: Authorship
author rank in publication: 13
linked author: Gilbert, Gary
linked information resource: A microengineered vascularized bleeding model that integrates the principal components of hemostasis.

A microengineered vascularized bleeding model that integrates the principal components of hemostasis.
PubMed Identifier: 29410404
author list: Sakurai Y, Hardy ET, Ahn B, Tran R, Fay ME, Ciciliano JC, Mannino RG, Myers DR, Qiu Y, Carden MA, Baldwin WH, Meeks SL, Gilbert GE, Jobe SM, Lam WA
published in: Nature communications
information resource reference: A microengineered vascularized bleeding model that integrates the principal components of hemostasis. Nat Commun. 2018 02 06; 9(1):509.
journal title abbreviation: Nat Commun
publication date: 2018-02-06T00:00:00
year: 2018
type: Academic Article
type: Article
type: Document
type: Information Resource

PADGEM protein: a receptor that mediates the interaction of activated platelets with neutrophils and monocytes.
PubMed Identifier: 2478294
author list: Larsen E, Celi A, Gilbert GE, Furie BC, Erban JK, Bonfanti R, Wagner DD, Furie B
published in: Cell
information resource reference: PADGEM protein: a receptor that mediates the interaction of activated platelets with neutrophils and monocytes. Cell. 1989 Oct 20; 59(2):305-12.
journal title abbreviation: Cell
publication date: 1989-10-20T00:00:00
year: 1989
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1070968
type: Authorship
author rank in publication: 1
linked author: Gilbert, Gary
linked information resource: The evolving understanding of factor VIII binding sites and implications for the treatment of hemophilia A.

The evolving understanding of factor VIII binding sites and implications for the treatment of hemophilia A.
PubMed Identifier: 29866493
author list: Gilbert GE
published in: Blood reviews
information resource reference: The evolving understanding of factor VIII binding sites and implications for the treatment of hemophilia A. Blood Rev. 2019 01; 33:1-5.
journal title abbreviation: Blood Rev
publication date: 2018-05-24T00:00:00
year: 2018
type: Academic Article
type: Article
type: Document
type: Information Resource

Lysine 5 and phenylalanine 9 of the factor IX omega-loop interact with phosphatidylserine in a membrane-mimetic environment.
PubMed Identifier: 15581349
author list: Grant MA, Baikeev RF, Gilbert GE, Rigby AC
published in: Biochemistry
information resource reference: Lysine 5 and phenylalanine 9 of the factor IX omega-loop interact with phosphatidylserine in a membrane-mimetic environment. Biochemistry. 2004 Dec 14; 43(49):15367-78.
journal title abbreviation: Biochemistry
publication date: 2004-12-14T00:00:00
year: 2004
type: Academic Article
type: Article
type: Document
type: Information Resource

Factor VIII C1 domain residues Lys 2092 and Phe 2093 contribute to membrane binding and cofactor activity.
PubMed Identifier: 19687511
author list: Meems H, Meijer AB, Cullinan DB, Mertens K, Gilbert GE
published in: Blood
information resource reference: Factor VIII C1 domain residues Lys 2092 and Phe 2093 contribute to membrane binding and cofactor activity. Blood. 2009 Oct 29; 114(18):3938-46.
journal title abbreviation: Blood
publication date: 2009-08-17T00:00:00
year: 2009
type: Academic Article
type: Article
type: Document
type: Information Resource

Phosphatidylethanolamine induces high affinity binding sites for factor VIII on membranes containing phosphatidyl-L-serine.
PubMed Identifier: 7629178
author list: Gilbert GE, Arena AA
published in: The Journal of biological chemistry
information resource reference: Phosphatidylethanolamine induces high affinity binding sites for factor VIII on membranes containing phosphatidyl-L-serine. J Biol Chem. 1995 Aug 04; 270(31):18500-5.
journal title abbreviation: J Biol Chem
publication date: 1995-08-04T00:00:00
year: 1995
type: Academic Article
type: Article
type: Document
type: Information Resource

Lactadherin blocks thrombosis and hemostasis in vivo: correlation with platelet phosphatidylserine exposure.
PubMed Identifier: 18485093
author list: Shi J, Pipe SW, Rasmussen JT, Heegaard CW, Gilbert GE
published in: Journal of thrombosis and haemostasis : JTH
information resource reference: Lactadherin blocks thrombosis and hemostasis in vivo: correlation with platelet phosphatidylserine exposure. J Thromb Haemost. 2008 Jul; 6(7):1167-74.
journal title abbreviation: J Thromb Haemost
publication date: 2008-07-01T00:00:00
year: 2008
type: Academic Article
type: Article
type: Document
type: Information Resource

Phosphatidylserine exposure and procoagulant activity in acute promyelocytic leukemia.
PubMed Identifier: 20102487
author list: Zhou J, Shi J, Hou J, Cao F, Zhang Y, Rasmussen JT, Heegaard CW, Gilbert GE
published in: Journal of thrombosis and haemostasis : JTH
information resource reference: Phosphatidylserine exposure and procoagulant activity in acute promyelocytic leukemia. J Thromb Haemost. 2010 Apr; 8(4):773-82.
journal title abbreviation: J Thromb Haemost
publication date: 2010-01-21T00:00:00
year: 2010
type: Academic Article
type: Article
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Authorship 111484
type: Authorship
author rank in publication: 3
linked author: Gilbert, Gary
linked information resource: Bovine lactadherin as a calcium-independent imaging agent of phosphatidylserine expressed on the surface of apoptotic HeLa cells.

Bovine lactadherin as a calcium-independent imaging agent of phosphatidylserine expressed on the surface of apoptotic HeLa cells.
PubMed Identifier: 19546474
author list: Waehrens LN, Heegaard CW, Gilbert GE, Rasmussen JT
published in: The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society
information resource reference: Bovine lactadherin as a calcium-independent imaging agent of phosphatidylserine expressed on the surface of apoptotic HeLa cells. J Histochem Cytochem. 2009 Oct; 57(10):907-14.
journal title abbreviation: J Histochem Cytochem
publication date: 2009-06-22T00:00:00
year: 2009
type: Academic Article
type: Article
type: Document
type: Information Resource

Daunorubicin induces procoagulant response through phosphatidylserine exposure in red blood cells.
PubMed Identifier: 19800661
author list: Zhou J, Zheng Y, Shi J, Lu C, Hou J, Yu H, Qiao X, Qi S, Gilbert GE
published in: Thrombosis research
information resource reference: Daunorubicin induces procoagulant response through phosphatidylserine exposure in red blood cells. Thromb Res. 2010 Feb; 125(2):178-83.
journal title abbreviation: Thromb Res
publication date: 2009-10-02T00:00:00
year: 2009
type: Academic Article
type: Article
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Authorship 109834
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author rank in publication: 2
linked author: Gilbert, Gary
linked information resource: Lactadherin inhibits enzyme complexes of blood coagulation by competing for phospholipid-binding sites.

Phosphatidylserines
MeSH DescriptorUI: D010718
MeSH semantic group name: Chemicals & Drugs
number of authors: 114
number of publications: 188
uniqueness weight: 0.888547
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Factor VIII
MeSH DescriptorUI: D005169
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number of authors: 171
number of publications: 365
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Factor V
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number of authors: 94
number of publications: 168
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Milk Proteins
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number of publications: 162
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Phospholipids
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number of publications: 776
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Emeritus
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Medicine
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Brigham and Women's Hospital
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Lutskiy, Maxim
eCommons Login: ML9
first name: Maxim
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full name: Maxim I Lutskiy, M.D.
has faculty rank: Instructor
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Person ID: 17619
person in primary position: Instructor in Pediatrics
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Springer, Timothy
eCommons Login: TAS3
first name: Timothy
last name: Springer
full name: Timothy Alan Springer, Ph.D.
has faculty rank: Full Professor
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Person ID: 14719
person in primary position: Latham Family Professor of Biological Chemistry and Molecular Pharmacology
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Croteau, Stacy
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first name: Stacy
last name: Croteau
full name: Stacy Emily Croteau, M.D.
has faculty rank: Assistant Professor
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Person ID: 84283
person in primary position: Assistant Professor of Pediatrics
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Michelson, Alan
eCommons Login: ADM22
first name: Alan
last name: Michelson
full name: Alan D Michelson, M.B.,B.S.
has faculty rank: Full Professor
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Person ID: 43322
person in primary position: Professor of Pediatrics and Medicine, Emeritus
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Authorship 129545
type: Authorship
author rank in publication: 5
linked author: Gilbert, Gary
linked information resource: WASP plays a novel role in regulating platelet responses dependent on alphaIIbbeta3 integrin outside-in signalling.

Ewenstein, Bruce
eCommons Login: BME3
first name: Bruce
last name: Ewenstein
full name: Bruce M. Ewenstein, M.D.,Ph.D.
has faculty rank: Lecturer
Person ID: 598
person in primary position: Lecturer on Pediatrics, Part-time
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preferred title: Lecturer on Pediatrics, Part-time

Wagner, Denisa
eCommons Login: DDW1
first name: Denisa
last name: Wagner
full name: Denisa D. Wagner, Ph.D.
has faculty rank: Full Professor
latitude: 42.33849900000000
longitude: -71.10446000000000
Person ID: 52822
person in primary position: Professor of Pediatrics
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preferred title: Professor of Pediatrics

Sage, Peter
eCommons Login: PTS6
first name: Peter
last name: Sage
full name: Peter The Sage, Ph.D.
has faculty rank: Associate Professor
latitude: 42.33837200000000
longitude: -71.10326900000000
Person ID: 58487
person in primary position: Associate Professor of Medicine
type: Agent
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preferred title: Associate Professor of Medicine

selected publications
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Authorship 143139
type: Authorship
author rank in publication: 1
linked author: Gilbert, Gary
linked information resource: Four hydrophobic amino acids of the factor VIII C2 domain are constituents of both the membrane-binding and von Willebrand factor-binding motifs.

Authorship 152297
type: Authorship
author rank in publication: 1
linked author: Gilbert, Gary
linked information resource: Specific membrane binding of factor VIII is mediated by O-phospho-L-serine, a moiety of phosphatidylserine.

Associate Professor of Medicine
is primary position: true
position in department: Medicine
position in division: VA Med Centers
sort order: 1
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HR job title: Associate Professor of Medicine
position in organization: Veterans Affairs Boston Healthcare System

Authorship 182962
type: Authorship
author rank in publication: 4
linked author: Gilbert, Gary
linked information resource: PADGEM-dependent adhesion of platelets to monocytes and neutrophils is mediated by a lineage-specific carbohydrate, LNF III (CD15).

Authorship 1250491
type: Authorship
author rank in publication: 7
linked author: Gilbert, Gary
linked information resource: Unexpected enhancement of FVIII immunogenicity by endothelial expression in lentivirus-transduced and transgenic mice.

Unexpected enhancement of FVIII immunogenicity by endothelial expression in lentivirus-transduced and transgenic mice.
PubMed Identifier: 32453842
author list: Shi Q, Carman CV, Chen Y, Sage PT, Xue F, Liang XM, Gilbert GE
published in: Blood advances
information resource reference: Unexpected enhancement of FVIII immunogenicity by endothelial expression in lentivirus-transduced and transgenic mice. Blood Adv. 2020 05 26; 4(10):2272-2285.
journal title abbreviation: Blood Adv
publication date: 2020-05-26T00:00:00
year: 2020
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1254528
type: Authorship
author rank in publication: 4
linked author: Gilbert, Gary
linked information resource: Discordance between platelet-supported and vesicle-supported factor VIII activity in the presence of anti-C2 domain inhibitory antibodies.

Discordance between platelet-supported and vesicle-supported factor VIII activity in the presence of anti-C2 domain inhibitory antibodies.
PubMed Identifier: 32558078
author list: Chatterjee M, Meeks S, Novakovic VA, Gilbert GE
published in: Journal of thrombosis and haemostasis : JTH
information resource reference: Discordance between platelet-supported and vesicle-supported factor VIII activity in the presence of anti-C2 domain inhibitory antibodies. J Thromb Haemost. 2020 12; 18(12):3184-3193.
journal title abbreviation: J Thromb Haemost
publication date: 2020-10-21T00:00:00
year: 2020
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1261933
type: Authorship
author rank in publication: 2
linked author: Gilbert, Gary
linked information resource: Procoagulant activities of skeletal and cardiac muscle myosin depend on contaminating phospholipid.

Procoagulant activities of skeletal and cardiac muscle myosin depend on contaminating phospholipid.
PubMed Identifier: 32604409
author list: Novakovic VA, Gilbert GE
published in: Blood
information resource reference: Procoagulant activities of skeletal and cardiac muscle myosin depend on contaminating phospholipid. Blood. 2020 11 19; 136(21):2469-2472.
journal title abbreviation: Blood
publication date: 2020-11-19T00:00:00
year: 2020
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 152122
type: Authorship
author rank in publication: 4
linked author: Gilbert, Gary
linked information resource: Lactadherin binds selectively to membranes containing phosphatidyl-L-serine and increased curvature.

Authorship 163711
type: Authorship
author rank in publication: 2
linked author: Gilbert, Gary
linked information resource: Role of the liver in regulating numbers of circulating neutrophils.

Stowell, Sean
eCommons Login: ses224
first name: Sean
last name: Stowell
full name: Sean R. Stowell, M.D.
has faculty rank: Full Professor
Person ID: 193107
person in primary position: Professor of Pathology
type: Agent
type: Person
preferred title: Professor of Pathology

BCMP
type: Department
type: Organization

Authorship 1350099
type: Authorship
author rank in publication: 2
linked author: Gilbert, Gary
linked information resource: Factor V mutation illuminates the dominant anticoagulant role and importance of an unidentified platelet modifier.

Factor V mutation illuminates the dominant anticoagulant role and importance of an unidentified platelet modifier.
PubMed Identifier: 33880872
author list: Ahnström J, Gilbert GE
published in: Journal of thrombosis and haemostasis : JTH
information resource reference: Factor V mutation illuminates the dominant anticoagulant role and importance of an unidentified platelet modifier. J Thromb Haemost. 2021 05; 19(5):1168-1170.
journal title abbreviation: J Thromb Haemost
publication date: 2021-05-01T00:00:00
year: 2021
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 149962
type: Authorship
author rank in publication: 2
linked author: Gilbert, Gary
linked information resource: Membrane phosphatidylserine regulates surface charge and protein localization.

Authorship 1359151
type: Authorship
author rank in publication: 1
linked author: Gilbert, Gary
linked information resource: Factor VIII-antibody structure and membrane binding.

Factor VIII-antibody structure and membrane binding.
PubMed Identifier: 34042979
author list: Gilbert GE
published in: Blood
information resource reference: Factor VIII-antibody structure and membrane binding. Blood. 2021 05 27; 137(21):2866-2868.
journal title abbreviation: Blood
publication date: 2021-05-27T00:00:00
year: 2021
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 202696
type: Authorship
author rank in publication: 5
linked author: Gilbert, Gary
linked information resource: Amphipathic helices support function of blood coagulation factor IXa.

Authorship 322422
type: Authorship
author rank in publication: 4
linked author: Gilbert, Gary
linked information resource: Membrane binding kinetics of factor VIII indicate a complex binding process.

Authorship 1466039
type: Authorship
author rank in publication: 8
linked author: Gilbert, Gary
linked information resource: Membrane curvature and PS localize coagulation proteins to filopodia and retraction fibers of endothelial cells.

Membrane curvature and PS localize coagulation proteins to filopodia and retraction fibers of endothelial cells.
PubMed Identifier: 35849711
author list: Carman CV, Nikova DN, Sakurai Y, Shi J, Novakovic VA, Rasmussen JT, Lam WA, Gilbert GE
published in: Blood advances
information resource reference: Membrane curvature and PS localize coagulation proteins to filopodia and retraction fibers of endothelial cells. Blood Adv. 2023 01 10; 7(1):60-72.
journal title abbreviation: Blood Adv
publication date: 2023-01-10T00:00:00
year: 2023
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 160172
type: Authorship
author rank in publication: 5
linked author: Gilbert, Gary
linked information resource: Lactadherin blocks thrombosis and hemostasis in vivo: correlation with platelet phosphatidylserine exposure.

Authorship 199715
type: Authorship
author rank in publication: 3
linked author: Gilbert, Gary
linked information resource: Lysine 5 and phenylalanine 9 of the factor IX omega-loop interact with phosphatidylserine in a membrane-mimetic environment.

Authorship 425800
type: Authorship
author rank in publication: 9
linked author: Gilbert, Gary
linked information resource: Daunorubicin induces procoagulant response through phosphatidylserine exposure in red blood cells.

Authorship 239109
type: Authorship
author rank in publication: 3
linked author: Gilbert, Gary
linked information resource: Fibrin stimulates platelets to increase factor VIIIa binding site expression.

Authorship 1669826
type: Authorship
author rank in publication: 1
linked author: Gilbert, Gary
linked information resource: Unexpected bleeding with platelet phosphatidylserine exposure defect: new kindred motivates rethinking Scott syndrome.

Unexpected bleeding with platelet phosphatidylserine exposure defect: new kindred motivates rethinking Scott syndrome.
PubMed Identifier: 39048266
author list: Gilbert GE
published in: Journal of thrombosis and haemostasis : JTH
information resource reference: Unexpected bleeding with platelet phosphatidylserine exposure defect: new kindred motivates rethinking Scott syndrome. J Thromb Haemost. 2024 Aug; 22(8):2147-2149.
journal title abbreviation: J Thromb Haemost
publication date: 2024-08-01T00:00:00
year: 2024
type: Academic Article
type: Article
type: Document
type: Information Resource

Associate Professor of Medicine
is primary position: true
position in department: Medicine
position in division: Renal
sort order: 1
type: Position
HR job title: Associate Professor of Medicine
position in organization: Brigham and Women's Hospital

Authorship 660273
type: Authorship
author rank in publication: 6
linked author: Gilbert, Gary
linked information resource: Membrane-binding properties of the Factor VIII C2 domain.

Authorship 650361
type: Authorship
author rank in publication: 1
linked author: Gilbert, Gary
linked information resource: Conservative mutations in the C2 domains of factor VIII and factor V alter phospholipid binding and cofactor activity.

Authorship 640777
type: Authorship
author rank in publication: 4
linked author: Gilbert, Gary
linked information resource: Lactadherin binds to phosphatidylserine-containing vesicles in a two-step mechanism sensitive to vesicle size and composition.

Authorship 651446
type: Authorship
author rank in publication: 10
linked author: Gilbert, Gary
linked information resource: Daunorubicin induces procoagulant activity of cultured endothelial cells through phosphatidylserine exposure and microparticles release.

Authorship 654442
type: Authorship
author rank in publication: 5
linked author: Gilbert, Gary
linked information resource: A membrane-interactive surface on the factor VIII C1 domain cooperates with the C2 domain for cofactor function.

Authorship 646768
type: Authorship
author rank in publication: 1
linked author: Gilbert, Gary
linked information resource: Curbing an inhibitor for hemostasis.

Authorship 655482
type: Authorship
author rank in publication: 9
linked author: Gilbert, Gary
linked information resource: Phagocytosis by macrophages and endothelial cells inhibits procoagulant and fibrinolytic activity of acute promyelocytic leukemia cells.

Authorship 643058
type: Authorship
author rank in publication: 6
linked author: Gilbert, Gary
linked information resource: Backbone resonance assignments of the C2 domain of coagulation factor VIII.

Phagocytosis by macrophages and endothelial cells inhibits procoagulant and fibrinolytic activity of acute promyelocytic leukemia cells.
PubMed Identifier: 22138513
author list: Xie R, Gao C, Li W, Zhu J, Novakovic V, Wang J, Ma R, Zhou J, Gilbert GE, Shi J
published in: Blood
information resource reference: Phagocytosis by macrophages and endothelial cells inhibits procoagulant and fibrinolytic activity of acute promyelocytic leukemia cells. Blood. 2012 Mar 08; 119(10):2325-34.
journal title abbreviation: Blood
publication date: 2011-12-02T00:00:00
year: 2011
type: Academic Article
type: Article
type: Document
type: Information Resource

Lactadherin binds to phosphatidylserine-containing vesicles in a two-step mechanism sensitive to vesicle size and composition.
PubMed Identifier: 21920348
author list: Otzen DE, Blans K, Wang H, Gilbert GE, Rasmussen JT
published in: Biochimica et biophysica acta
information resource reference: Lactadherin binds to phosphatidylserine-containing vesicles in a two-step mechanism sensitive to vesicle size and composition. Biochim Biophys Acta. 2012 Apr; 1818(4):1019-27.
journal title abbreviation: Biochim Biophys Acta
publication date: 2011-09-02T00:00:00
year: 2011
type: Academic Article
type: Article
type: Document
type: Information Resource

Backbone resonance assignments of the C2 domain of coagulation factor VIII.
PubMed Identifier: 22392338
author list: Nuzzio KM, Cullinan DB, Novakovic VA, Boettcher JM, Rienstra CM, Gilbert GE, Baleja JD
published in: Biomolecular NMR assignments
information resource reference: Backbone resonance assignments of the C2 domain of coagulation factor VIII. Biomol NMR Assign. 2013 Apr; 7(1):31-4.
journal title abbreviation: Biomol NMR Assign
publication date: 2012-03-06T00:00:00
year: 2012
type: Academic Article
type: Article
type: Document
type: Information Resource

Endothelial cell phagocytosis of senescent neutrophils decreases procoagulant activity.
PubMed Identifier: 23571768
author list: Gao C, Xie R, Li W, Zhou J, Liu S, Cao F, Liu Y, Ma R, Si Y, Liu Y, Bi Y, Gilbert GE, Shi J
published in: Thrombosis and haemostasis
information resource reference: Endothelial cell phagocytosis of senescent neutrophils decreases procoagulant activity. Thromb Haemost. 2013 Jun; 109(6):1079-90.
journal title abbreviation: Thromb Haemost
publication date: 2013-04-04T00:00:00
year: 2013
type: Academic Article
type: Article
type: Document
type: Information Resource

A membrane-interactive surface on the factor VIII C1 domain cooperates with the C2 domain for cofactor function.
PubMed Identifier: 21156843
author list: Lü J, Pipe SW, Miao H, Jacquemin M, Gilbert GE
published in: Blood
information resource reference: A membrane-interactive surface on the factor VIII C1 domain cooperates with the C2 domain for cofactor function. Blood. 2011 Mar 17; 117(11):3181-9.
journal title abbreviation: Blood
publication date: 2010-12-14T00:00:00
year: 2010
type: Academic Article
type: Article
type: Document
type: Information Resource

Curbing an inhibitor for hemostasis.
PubMed Identifier: 21596863
author list: Gilbert GE, Mast AE
published in: Blood
information resource reference: Curbing an inhibitor for hemostasis. Blood. 2011 May 19; 117(20):5277-8.
journal title abbreviation: Blood
publication date: 2011-05-19T00:00:00
year: 2011
type: Academic Article
type: Article
type: Document
type: Information Resource

Membrane-binding properties of the Factor VIII C2 domain.
PubMed Identifier: 21210768
author list: Novakovic VA, Cullinan DB, Wakabayashi H, Fay PJ, Baleja JD, Gilbert GE
published in: The Biochemical journal
information resource reference: Membrane-binding properties of the Factor VIII C2 domain. Biochem J. 2011 Apr 01; 435(1):187-96.
journal title abbreviation: Biochem J
publication date: 2011-04-01T00:00:00
year: 2011
type: Academic Article
type: Article
type: Document
type: Information Resource

Daunorubicin induces procoagulant activity of cultured endothelial cells through phosphatidylserine exposure and microparticles release.
PubMed Identifier: 20886178
author list: Fu Y, Zhou J, Li H, Cao F, Su Y, Fan S, Li Y, Wang S, Li L, Gilbert GE, Shi J
published in: Thrombosis and haemostasis
information resource reference: Daunorubicin induces procoagulant activity of cultured endothelial cells through phosphatidylserine exposure and microparticles release. Thromb Haemost. 2010 Dec; 104(6):1235-41.
journal title abbreviation: Thromb Haemost
publication date: 2010-09-30T00:00:00
year: 2010
type: Academic Article
type: Article
type: Document
type: Information Resource

Conservative mutations in the C2 domains of factor VIII and factor V alter phospholipid binding and cofactor activity.
PubMed Identifier: 22613792
author list: Gilbert GE, Novakovic VA, Kaufman RJ, Miao H, Pipe SW
published in: Blood
information resource reference: Conservative mutations in the C2 domains of factor VIII and factor V alter phospholipid binding and cofactor activity. Blood. 2012 Aug 30; 120(9):1923-32.
journal title abbreviation: Blood
publication date: 2012-05-21T00:00:00
year: 2012
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 578763
type: Authorship
linked author: Gilbert, Gary
linked information resource: Use of lactadherin as an anticoagulant

Authorship 691593
type: Authorship
author rank in publication: 4
linked author: Gilbert, Gary
linked information resource: Lactadherin inhibits secretory phospholipase A2 activity on pre-apoptotic leukemia cells.

Lactadherin inhibits secretory phospholipase A2 activity on pre-apoptotic leukemia cells.
PubMed Identifier: 24194865
author list: Nyegaard S, Novakovic VA, Rasmussen JT, Gilbert GE
published in: PloS one
information resource reference: Lactadherin inhibits secretory phospholipase A2 activity on pre-apoptotic leukemia cells. PLoS One. 2013; 8(10):e77143.
journal title abbreviation: PLoS One
publication date: 2013-10-23T00:00:00
year: 2013
type: Academic Article
type: Article
type: Document
type: Information Resource

Professor of Pediatrics and Medicine, Emeritus
is primary position: true
position in department: Emeritus
position in division: https://connects.catalyst.harvard.edu/Profiles/profile/1229413
sort order: 1
type: Position
HR job title: Professor of Pediatrics and Medicine, Emeritus
position in organization: Harvard Medical School

Authorship 699298
type: Authorship
author rank in publication: 1
linked author: Gilbert, Gary
linked information resource: Factor VIII inhibitor epitopes and an enigma.

Factor VIII inhibitor epitopes and an enigma.
PubMed Identifier: 24357711
author list: Gilbert GE
published in: Blood
information resource reference: Factor VIII inhibitor epitopes and an enigma. Blood. 2013 Dec 19; 122(26):4160-1.
journal title abbreviation: Blood
publication date: 2013-12-19T00:00:00
year: 2013
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 251452
type: Authorship
author rank in publication: 5
linked author: Gilbert, Gary
linked information resource: Crystal structure of lactadherin C2 domain at 1.7A resolution with mutational and computational analyses of its membrane-binding motif.

Authorship 718902
type: Authorship
author rank in publication: 12
linked author: Gilbert, Gary
linked information resource: Endothelial cell phagocytosis of senescent neutrophils decreases procoagulant activity.

Authorship 88116
type: Authorship
author rank in publication: 1
linked author: Gilbert, Gary
linked information resource: Partial activation of the factor VIIIa-factor IXa enzyme complex by dihexanoic phosphatidylserine at submicellar concentrations.

Authorship 99137
type: Authorship
author rank in publication: 2
linked author: Gilbert, Gary
linked information resource: Some factor VIII inhibitor antibodies recognize a common epitope corresponding to C2 domain amino acids 2248 through 2312, which overlap a phospholipid-binding site.

Instructor in Pediatrics
is primary position: true
position in department: Pediatrics
position in division: Allergy/Immunology
sort order: 1
type: Position
HR job title: Instructor in Pediatrics
position in organization: Massachusetts General Hospital

Authorship 32464
type: Authorship
author rank in publication: 4
linked author: Gilbert, Gary
linked information resource: Binding of factor VIII to von willebrand factor is enabled by cleavage of the von Willebrand factor propeptide and enhanced by formation of disulfide-linked multimers.

Authorship 33903
type: Authorship
author rank in publication: 3
linked author: Gilbert, Gary
linked information resource: Structure and topography of the membrane-binding C2 domain of factor VIII in the presence of dodecylphosphocholine micelles.

Authorship 743195
type: Authorship
author rank in publication: 4
linked author: Gilbert, Gary
linked information resource: Changes in the Factor VIII C2 domain upon membrane binding determined by hydrogen-deuterium exchange MS.

Changes in the Factor VIII C2 domain upon membrane binding determined by hydrogen-deuterium exchange MS.
PubMed Identifier: 24814520
author list: Pantazatos D, Gessner CR, Woods VL, Gilbert GE
published in: The Biochemical journal
information resource reference: Changes in the Factor VIII C2 domain upon membrane binding determined by hydrogen-deuterium exchange MS. Biochem J. 2014 Aug 01; 461(3):443-51.
journal title abbreviation: Biochem J
publication date: 2014-08-01T00:00:00
year: 2014
type: Academic Article
type: Article
type: Document
type: Information Resource

Professor of Pathology
is primary position: true
position in department: Pathology
position in division: https://connects.catalyst.harvard.edu/Profiles/profile/1229413
sort order: 1
type: Position
HR job title: Professor of Pathology
position in organization: Brigham and Women's Hospital

Latham Family Professor of Biological Chemistry and Molecular Pharmacology
is primary position: true
position in department: BCMP
position in division: https://connects.catalyst.harvard.edu/Profiles/profile/1229413
sort order: 1
type: Position
HR job title: Latham Family Professor of Biological Chemistry and Molecular Pharmacology
position in organization: Boston Children's Hospital

Lecturer on Pediatrics, Part-time
is primary position: true
position in department: Pediatrics
position in division: Hematology/Oncology
sort order: 1
type: Position
HR job title: Lecturer on Pediatrics, Part-time
position in organization: Boston Children's Hospital

Professor of Pediatrics
is primary position: true
position in department: Pediatrics
position in division: Hematology/Oncology
sort order: 1
type: Position
HR job title: Professor of Pediatrics
position in organization: Boston Children's Hospital

Assistant Professor of Pediatrics
is primary position: true
position in department: Pediatrics
position in division: Hematology/Oncology
sort order: 1
type: Position
HR job title: Assistant Professor of Pediatrics
position in organization: Boston Children's Hospital

Authorship 376109
type: Authorship
author rank in publication: 7
linked author: Gilbert, Gary
linked information resource: Procoagulant activity and phosphatidylserine of amniotic fluid cells.

Authorship 361362
type: Authorship
author rank in publication: 1
linked author: Gilbert, Gary
linked information resource: Membrane-binding peptide from the C2 domain of factor VIII forms an amphipathic structure as determined by NMR spectroscopy.

Authorship 451795
type: Authorship
author rank in publication: 3
linked author: Gilbert, Gary
linked information resource: Collagen-bound von Willebrand factor has reduced affinity for factor VIII.

Authorship 527275
type: Authorship
author rank in publication: 1
linked author: Gilbert, Gary
linked information resource: Unsaturated phospholipid acyl chains are required to constitute membrane binding sites for factor VIII.

Authorship 169151
type: Authorship
author rank in publication: 1
linked author: Gilbert, Gary
linked information resource: Platelet-derived microparticles express high affinity receptors for factor VIII.

Authorship 91025
type: Authorship
author rank in publication: 1
linked author: Gilbert, Gary
linked information resource: Binding of human factor VIII to phospholipid vesicles.

Authorship 448895
type: Authorship
author rank in publication: 1
linked author: Gilbert, Gary
linked information resource: Where does von Willebrand factor go?

Authorship 192571
type: Authorship
author rank in publication: 3
linked author: Gilbert, Gary
linked information resource: PADGEM protein: a receptor that mediates the interaction of activated platelets with neutrophils and monocytes.

Authorship 235962
type: Authorship
author rank in publication: 5
linked author: Gilbert, Gary
linked information resource: Factor VIII C1 domain residues Lys 2092 and Phe 2093 contribute to membrane binding and cofactor activity.

Authorship 340652
type: Authorship
author rank in publication: 1
linked author: Gilbert, Gary
linked information resource: Specificity of phosphatidylserine-containing membrane binding sites for factor VIII. Studies with model membranes supported by glass microspheres (lipospheres).

Authorship 569050
type: Authorship
author rank in publication: 6
linked author: Gilbert, Gary
linked information resource: Lactadherin detects early phosphatidylserine exposure on immortalized leukemia cells undergoing programmed cell death.

Authorship 834107
type: Authorship
author rank in publication: 1
linked author: Gilbert, Gary
linked information resource: Platelet binding sites for factor VIII in relation to fibrin and phosphatidylserine.

Platelet binding sites for factor VIII in relation to fibrin and phosphatidylserine.
PubMed Identifier: 26162408
author list: Gilbert GE, Novakovic VA, Shi J, Rasmussen J, Pipe SW
published in: Blood
information resource reference: Platelet binding sites for factor VIII in relation to fibrin and phosphatidylserine. Blood. 2015 Sep 03; 126(10):1237-44.
journal title abbreviation: Blood
publication date: 2015-07-10T00:00:00
year: 2015
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 72729
type: Authorship
author rank in publication: 1
linked author: Gilbert, Gary
linked information resource: Use of microsphere-supported phospholipid membranes for analysis of protein-lipid interactions.

Authorship 847360
type: Authorship
author rank in publication: 16
linked author: Gilbert, Gary
linked information resource: Thrombotic Role of Blood and Endothelial Cells in Uremia through Phosphatidylserine Exposure and Microparticle Release.

Thrombotic Role of Blood and Endothelial Cells in Uremia through Phosphatidylserine Exposure and Microparticle Release.
PubMed Identifier: 26580207
author list: Gao C, Xie R, Yu C, Ma R, Dong W, Meng H, Zhang Y, Si Y, Zhang Z, Novakovic V, Zhang Y, Kou J, Bi Y, Li B, Xie R, Gilbert GE, Zhou J, Shi J
published in: PloS one
information resource reference: Thrombotic Role of Blood and Endothelial Cells in Uremia through Phosphatidylserine Exposure and Microparticle Release. PLoS One. 2015; 10(11):e0142835.
journal title abbreviation: PLoS One
publication date: 2015-11-16T00:00:00
year: 2015
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 371880
type: Authorship
author rank in publication: 1
linked author: Gilbert, Gary
linked information resource: Phosphatidylethanolamine induces high affinity binding sites for factor VIII on membranes containing phosphatidyl-L-serine.

Assistant Professor
sort order: 2
type: Faculty Rank

Associate Professor
sort order: 1
type: Faculty Rank

Full Professor
sort order: 0
type: Faculty Rank

Instructor
sort order: 4
type: Faculty Rank

Lecturer
sort order: 3
type: Faculty Rank

Authorship 52021
type: Authorship
author rank in publication: 1
linked author: Gilbert, Gary
linked information resource: Activation of the factor VIIIa-factor IXa enzyme complex of blood coagulation by membranes containing phosphatidyl-L-serine.

Authorship 594864
type: Authorship
linked author: Gilbert, Gary
linked information resource: Method, composition, and kit for detecting phosphatidylserine(PS) on cell membranes

PLATELET PROTEINS ASSOCIATED WITH PLATELET ACTIVATION
end date: 1900-01-01
principal investigator name: GILBERT, GARY E
start date: 1986-07-01
type: Grant
sponsor award id: F32HL007440

Endothelial topography, phosphatidylserine, and procoagulant activity
end date: 2025-03-31
principal investigator name: GILBERT, GARY E
start date: 2012-01-01
type: Grant
sponsor award id: I01BX001352

FUNCTION OF FACTOR VIII ON THE PLATELET MEMBRANE
end date: 2003-05-31
principal investigator name: GILBERT, GARY E
start date: 1998-06-01
type: Grant
sponsor award id: R01HL057867

MEMBRANE PROTEINS IN BLOOD COAGULATION
end date: 2005-08-31
principal investigator name: FURIE, BARBARA C
start date: 1989-04-01
type: Grant
sponsor award id: P01HL042443

COORDINATE FUNCTION OF ENZYME COMPLEXES IN HEMOSTASIS
end date: 1996-04-30
principal investigator name: GILBERT, GARY E
start date: 1991-05-01
type: Grant
sponsor award id: K08HL002587

Co-Principal Investigator
type: Researcher Role
researcher role of: Gilbert, Gary
contributes to: MEMBRANE PROTEINS IN BLOOD COAGULATION

Principal Investigator
type: Researcher Role
researcher role of: Gilbert, Gary
contributes to: PLATELET PROTEINS ASSOCIATED WITH PLATELET ACTIVATION

Principal Investigator
type: Researcher Role
researcher role of: Gilbert, Gary
contributes to: FUNCTION OF FACTOR VIII ON THE PLATELET MEMBRANE

Principal Investigator
type: Researcher Role
researcher role of: Gilbert, Gary
contributes to: COORDINATE FUNCTION OF ENZYME COMPLEXES IN HEMOSTASIS

Principal Investigator
type: Researcher Role
researcher role of: Gilbert, Gary
contributes to: Endothelial topography, phosphatidylserine, and procoagulant activity

Authorship 71350
type: Authorship
author rank in publication: 8
linked author: Gilbert, Gary
linked information resource: Phosphatidylserine exposure and procoagulant activity in acute promyelocytic leukemia.

Authorship 380201
type: Authorship
author rank in publication: 3
linked author: Gilbert, Gary
linked information resource: Slowed release of thrombin-cleaved factor VIII from von Willebrand factor by a monoclonal and a human antibody is a novel mechanism for factor VIII inhibition.

Authorship 954349
type: Authorship
author rank in publication: 1
linked author: Gilbert, Gary
linked information resource: Inhibitory antibodies against factor VIII C1 domain.

Inhibitory antibodies against factor VIII C1 domain.
PubMed Identifier: 28157676
author list: Gilbert GE
published in: Blood
information resource reference: Inhibitory antibodies against factor VIII C1 domain. Blood. 2016 10 20; 128(16):2001-2002.
journal title abbreviation: Blood
publication date: 2016-10-20T00:00:00
year: 2016
type: Academic Article
type: Article
type: Document
type: Information Resource

Slowed release of thrombin-cleaved factor VIII from von Willebrand factor by a monoclonal and a human antibody is a novel mechanism for factor VIII inhibition.
PubMed Identifier: 8910322
author list: Saenko EL, Shima M, Gilbert GE, Scandella D
published in: The Journal of biological chemistry
information resource reference: Slowed release of thrombin-cleaved factor VIII from von Willebrand factor by a monoclonal and a human antibody is a novel mechanism for factor VIII inhibition. J Biol Chem. 1996 Nov 01; 271(44):27424-31.
journal title abbreviation: J Biol Chem
publication date: 1996-11-01T00:00:00
year: 1996
type: Academic Article
type: Article
type: Document
type: Information Resource

Partial activation of the factor VIIIa-factor IXa enzyme complex by dihexanoic phosphatidylserine at submicellar concentrations.
PubMed Identifier: 9271508
author list: Gilbert GE, Arena AA
published in: Biochemistry
information resource reference: Partial activation of the factor VIIIa-factor IXa enzyme complex by dihexanoic phosphatidylserine at submicellar concentrations. Biochemistry. 1997 Sep 02; 36(35):10768-76.
journal title abbreviation: Biochemistry
publication date: 1997-09-02T00:00:00
year: 1997
type: Academic Article
type: Article
type: Document
type: Information Resource

Role of the liver in regulating numbers of circulating neutrophils.
PubMed Identifier: 11493474
author list: Shi J, Gilbert GE, Kokubo Y, Ohashi T
published in: Blood
information resource reference: Role of the liver in regulating numbers of circulating neutrophils. Blood. 2001 Aug 15; 98(4):1226-30.
journal title abbreviation: Blood
publication date: 2001-08-15T00:00:00
year: 2001
type: Academic Article
type: Article
type: Document
type: Information Resource

Four hydrophobic amino acids of the factor VIII C2 domain are constituents of both the membrane-binding and von Willebrand factor-binding motifs.
PubMed Identifier: 11698391
author list: Gilbert GE, Kaufman RJ, Arena AA, Miao H, Pipe SW
published in: The Journal of biological chemistry
information resource reference: Four hydrophobic amino acids of the factor VIII C2 domain are constituents of both the membrane-binding and von Willebrand factor-binding motifs. J Biol Chem. 2002 Feb 22; 277(8):6374-81.
journal title abbreviation: J Biol Chem
publication date: 2001-11-06T00:00:00
year: 2001
type: Academic Article
type: Article
type: Document
type: Information Resource

Amphipathic helices support function of blood coagulation factor IXa.
PubMed Identifier: 11009614
author list: Blostein MD, Rigby AC, Furie BC, Furie B, Gilbert GE
published in: Biochemistry
information resource reference: Amphipathic helices support function of blood coagulation factor IXa. Biochemistry. 2000 Oct 03; 39(39):12000-6.
journal title abbreviation: Biochemistry
publication date: 2000-10-03T00:00:00
year: 2000
type: Academic Article
type: Article
type: Document
type: Information Resource

Fibrin stimulates platelets to increase factor VIIIa binding site expression.
PubMed Identifier: 15456493
author list: Phillips JE, Lord ST, Gilbert GE
published in: Journal of thrombosis and haemostasis : JTH
information resource reference: Fibrin stimulates platelets to increase factor VIIIa binding site expression. J Thromb Haemost. 2004 Oct; 2(10):1806-15.
journal title abbreviation: J Thromb Haemost
publication date: 2004-10-01T00:00:00
year: 2004
type: Academic Article
type: Article
type: Document
type: Information Resource

Binding of human factor VIII to phospholipid vesicles.
PubMed Identifier: 2104832
author list: Gilbert GE, Furie BC, Furie B
published in: The Journal of biological chemistry
information resource reference: Binding of human factor VIII to phospholipid vesicles. J Biol Chem. 1990 Jan 15; 265(2):815-22.
journal title abbreviation: J Biol Chem
publication date: 1990-01-15T00:00:00
year: 1990
type: Academic Article
type: Article
type: Document
type: Information Resource

Binding of factor VIII to von willebrand factor is enabled by cleavage of the von Willebrand factor propeptide and enhanced by formation of disulfide-linked multimers.
PubMed Identifier: 9657753
author list: Bendetowicz AV, Morris JA, Wise RJ, Gilbert GE, Kaufman RJ
published in: Blood
information resource reference: Binding of factor VIII to von willebrand factor is enabled by cleavage of the von Willebrand factor propeptide and enhanced by formation of disulfide-linked multimers. Blood. 1998 Jul 15; 92(2):529-38.
journal title abbreviation: Blood
publication date: 1998-07-15T00:00:00
year: 1998
type: Academic Article
type: Article
type: Document
type: Information Resource

Lactadherin inhibits enzyme complexes of blood coagulation by competing for phospholipid-binding sites.
PubMed Identifier: 12517809
author list: Shi J, Gilbert GE
published in: Blood
information resource reference: Lactadherin inhibits enzyme complexes of blood coagulation by competing for phospholipid-binding sites. Blood. 2003 Apr 01; 101(7):2628-36.
journal title abbreviation: Blood
publication date: 2002-11-27T00:00:00
year: 2002
type: Academic Article
type: Article
type: Document
type: Information Resource

Where does von Willebrand factor go?
PubMed Identifier: 18725568
author list: Gilbert GE
published in: Blood
information resource reference: Where does von Willebrand factor go? Blood. 2008 Sep 01; 112(5):1549-50.
journal title abbreviation: Blood
publication date: 2008-09-01T00:00:00
year: 2008
type: Academic Article
type: Article
type: Document
type: Information Resource

Lactadherin binds selectively to membranes containing phosphatidyl-L-serine and increased curvature.
PubMed Identifier: 15533308
author list: Shi J, Heegaard CW, Rasmussen JT, Gilbert GE
published in: Biochimica et biophysica acta
information resource reference: Lactadherin binds selectively to membranes containing phosphatidyl-L-serine and increased curvature. Biochim Biophys Acta. 2004 Nov 17; 1667(1):82-90.
journal title abbreviation: Biochim Biophys Acta
publication date: 2004-11-17T00:00:00
year: 2004
type: Academic Article
type: Article
type: Document
type: Information Resource

Procoagulant activity and phosphatidylserine of amniotic fluid cells.
PubMed Identifier: 19404537
author list: Zhou J, Liu S, Ma M, Hou J, Yu H, Lu C, Gilbert GE, Shi J
published in: Thrombosis and haemostasis
information resource reference: Procoagulant activity and phosphatidylserine of amniotic fluid cells. Thromb Haemost. 2009 May; 101(5):845-51.
journal title abbreviation: Thromb Haemost
publication date: 2009-05-01T00:00:00
year: 2009
type: Academic Article
type: Article
type: Document
type: Information Resource

150 S Huntington Ave
type: Address
address line 1: V.A. Medical Center - Boston
address line 2: 9th Floor, Rm 9D-136
address line 3: 150 S Huntington Ave
city: Jamaica Plain
postal code: 02130
state or province: MA

Membrane binding kinetics of factor VIII indicate a complex binding process.
PubMed Identifier: 8473326
author list: Bardelle C, Furie B, Furie BC, Gilbert GE
published in: The Journal of biological chemistry
information resource reference: Membrane binding kinetics of factor VIII indicate a complex binding process. J Biol Chem. 1993 Apr 25; 268(12):8815-24.
journal title abbreviation: J Biol Chem
publication date: 1993-04-25T00:00:00
year: 1993
type: Academic Article
type: Article
type: Document
type: Information Resource

Lactadherin detects early phosphatidylserine exposure on immortalized leukemia cells undergoing programmed cell death.
PubMed Identifier: 17123296
author list: Shi J, Shi Y, Waehrens LN, Rasmussen JT, Heegaard CW, Gilbert GE
published in: Cytometry. Part A : the journal of the International Society for Analytical Cytology
information resource reference: Lactadherin detects early phosphatidylserine exposure on immortalized leukemia cells undergoing programmed cell death. Cytometry A. 2006 Dec 01; 69(12):1193-201.
journal title abbreviation: Cytometry A
publication date: 2006-12-01T00:00:00
year: 2006
type: Academic Article
type: Article
type: Document
type: Information Resource

Crystal structure of lactadherin C2 domain at 1.7A resolution with mutational and computational analyses of its membrane-binding motif.
PubMed Identifier: 18160406
author list: Shao C, Novakovic VA, Head JF, Seaton BA, Gilbert GE
published in: The Journal of biological chemistry
information resource reference: Crystal structure of lactadherin C2 domain at 1.7A resolution with mutational and computational analyses of its membrane-binding motif. J Biol Chem. 2008 Mar 14; 283(11):7230-41.
journal title abbreviation: J Biol Chem
publication date: 2007-12-26T00:00:00
year: 2007
type: Academic Article
type: Article
type: Document
type: Information Resource

WASP plays a novel role in regulating platelet responses dependent on alphaIIbbeta3 integrin outside-in signalling.
PubMed Identifier: 19863535
author list: Shcherbina A, Cooley J, Lutskiy MI, Benarafa C, Gilbert GE, Remold-O'Donnell E
published in: British journal of haematology
information resource reference: WASP plays a novel role in regulating platelet responses dependent on alphaIIbbeta3 integrin outside-in signalling. Br J Haematol. 2010 Feb; 148(3):416-27.
journal title abbreviation: Br J Haematol
publication date: 2009-10-27T00:00:00
year: 2009
type: Academic Article
type: Article
type: Document
type: Information Resource

Structure and topography of the membrane-binding C2 domain of factor VIII in the presence of dodecylphosphocholine micelles.
PubMed Identifier: 9601086
author list: Veeraraghavan S, Baleja JD, Gilbert GE
published in: The Biochemical journal
information resource reference: Structure and topography of the membrane-binding C2 domain of factor VIII in the presence of dodecylphosphocholine micelles. Biochem J. 1998 Jun 01; 332 ( Pt 2):549-55.
journal title abbreviation: Biochem J
publication date: 1998-06-01T00:00:00
year: 1998
type: Academic Article
type: Article
type: Document
type: Information Resource

Platelet-derived microparticles express high affinity receptors for factor VIII.
PubMed Identifier: 1654328
author list: Gilbert GE, Sims PJ, Wiedmer T, Furie B, Furie BC, Shattil SJ
published in: The Journal of biological chemistry
information resource reference: Platelet-derived microparticles express high affinity receptors for factor VIII. J Biol Chem. 1991 Sep 15; 266(26):17261-8.
journal title abbreviation: J Biol Chem
publication date: 1991-09-15T00:00:00
year: 1991
type: Academic Article
type: Article
type: Document
type: Information Resource

Method, composition, and kit for detecting phosphatidylserine(PS) on cell membranes
author list: Gary E Gilbert Jialan Shi Christian W. Heegaard Jan T Rasmussen
published in: Method, composition, and kit for detecting phosphatidylserine(PS) on cell membranes
information resource reference: Method, composition, and kit for detecting phosphatidylserine(PS) on cell membranes. 2004.
publication date: 2004-06-24T00:00:00
year: 2004
type: Academic Article
type: Article
type: Document
type: Information Resource

Some factor VIII inhibitor antibodies recognize a common epitope corresponding to C2 domain amino acids 2248 through 2312, which overlap a phospholipid-binding site.
PubMed Identifier: 7544643
author list: Scandella D, Gilbert GE, Shima M, Nakai H, Eagleson C, Felch M, Prescott R, Rajalakshmi KJ, Hoyer LW, Saenko E
published in: Blood
information resource reference: Some factor VIII inhibitor antibodies recognize a common epitope corresponding to C2 domain amino acids 2248 through 2312, which overlap a phospholipid-binding site. Blood. 1995 Sep 01; 86(5):1811-9.
journal title abbreviation: Blood
publication date: 1995-09-01T00:00:00
year: 1995
type: Academic Article
type: Article
type: Document
type: Information Resource

Membrane-binding peptide from the C2 domain of factor VIII forms an amphipathic structure as determined by NMR spectroscopy.
PubMed Identifier: 7893714
author list: Gilbert GE, Baleja JD
published in: Biochemistry
information resource reference: Membrane-binding peptide from the C2 domain of factor VIII forms an amphipathic structure as determined by NMR spectroscopy. Biochemistry. 1995 Mar 07; 34(9):3022-31.
journal title abbreviation: Biochemistry
publication date: 1995-03-07T00:00:00
year: 1995
type: Academic Article
type: Article
type: Document
type: Information Resource

Collagen-bound von Willebrand factor has reduced affinity for factor VIII.
PubMed Identifier: 10212199
author list: Bendetowicz AV, Wise RJ, Gilbert GE
published in: The Journal of biological chemistry
information resource reference: Collagen-bound von Willebrand factor has reduced affinity for factor VIII. J Biol Chem. 1999 Apr 30; 274(18):12300-7.
journal title abbreviation: J Biol Chem
publication date: 1999-04-30T00:00:00
year: 1999
type: Academic Article
type: Article
type: Document
type: Information Resource

Membrane phosphatidylserine regulates surface charge and protein localization.
PubMed Identifier: 18187657
author list: Yeung T, Gilbert GE, Shi J, Silvius J, Kapus A, Grinstein S
published in: Science (New York, N.Y.)
information resource reference: Membrane phosphatidylserine regulates surface charge and protein localization. Science. 2008 Jan 11; 319(5860):210-3.
journal title abbreviation: Science
publication date: 2008-01-11T00:00:00
year: 2008
type: Academic Article
type: Article
type: Document
type: Information Resource

PADGEM-dependent adhesion of platelets to monocytes and neutrophils is mediated by a lineage-specific carbohydrate, LNF III (CD15).
PubMed Identifier: 1699666
author list: Larsen E, Palabrica T, Sajer S, Gilbert GE, Wagner DD, Furie BC, Furie B
published in: Cell
information resource reference: PADGEM-dependent adhesion of platelets to monocytes and neutrophils is mediated by a lineage-specific carbohydrate, LNF III (CD15). Cell. 1990 Nov 02; 63(3):467-74.
journal title abbreviation: Cell
publication date: 1990-11-02T00:00:00
year: 1990
type: Academic Article
type: Article
type: Document
type: Information Resource

Use of microsphere-supported phospholipid membranes for analysis of protein-lipid interactions.
PubMed Identifier: 18770819
author list: Gilbert GE
published in: Current protocols in cytometry
information resource reference: Use of microsphere-supported phospholipid membranes for analysis of protein-lipid interactions. Curr Protoc Cytom. 2005 Nov; Chapter 13:Unit13.3.
journal title abbreviation: Curr Protoc Cytom
publication date: 2005-11-01T00:00:00
year: 2005
type: Academic Article
type: Article
type: Document
type: Information Resource

Specific membrane binding of factor VIII is mediated by O-phospho-L-serine, a moiety of phosphatidylserine.
PubMed Identifier: 8373765
author list: Gilbert GE, Drinkwater D
published in: Biochemistry
information resource reference: Specific membrane binding of factor VIII is mediated by O-phospho-L-serine, a moiety of phosphatidylserine. Biochemistry. 1993 Sep 21; 32(37):9577-85.
journal title abbreviation: Biochemistry
publication date: 1993-09-21T00:00:00
year: 1993
type: Academic Article
type: Article
type: Document
type: Information Resource

Activation of the factor VIIIa-factor IXa enzyme complex of blood coagulation by membranes containing phosphatidyl-L-serine.
PubMed Identifier: 8626656
author list: Gilbert GE, Arena AA
published in: The Journal of biological chemistry
information resource reference: Activation of the factor VIIIa-factor IXa enzyme complex of blood coagulation by membranes containing phosphatidyl-L-serine. J Biol Chem. 1996 May 10; 271(19):11120-5.
journal title abbreviation: J Biol Chem
publication date: 1996-05-10T00:00:00
year: 1996
type: Academic Article
type: Article
type: Document
type: Information Resource

Use of lactadherin as an anticoagulant
author list: Gary E Gilbert Jialan Shi
published in: Use of lactadherin as an anticoagulant
information resource reference: Use of lactadherin as an anticoagulant. 2003.
publication date: 2003-06-24T00:00:00
year: 2003
type: Academic Article
type: Article
type: Document
type: Information Resource

Specificity of phosphatidylserine-containing membrane binding sites for factor VIII. Studies with model membranes supported by glass microspheres (lipospheres).
PubMed Identifier: 1639816
author list: Gilbert GE, Drinkwater D, Barter S, Clouse SB
published in: The Journal of biological chemistry
information resource reference: Specificity of phosphatidylserine-containing membrane binding sites for factor VIII. Studies with model membranes supported by glass microspheres (lipospheres). J Biol Chem. 1992 Aug 05; 267(22):15861-8.
journal title abbreviation: J Biol Chem
publication date: 1992-08-05T00:00:00
year: 1992
type: Academic Article
type: Article
type: Document
type: Information Resource