Golub Family Professor of Stem Cell and Regenerative Biology
The HMG I proteins: dynamic roles in gene activation, development, and tumorigenesis. Immunol Res. 2001; 24(1):13-29.
The HMG I proteins: dynamic roles in gene activation, development, and tumorigenesis.
Arlotta P, Curci G, Perazzoli CA, Santori L
[Reconstruction of severe loss of mandibular bone substance using metal prostheses]. Minerva Stomatol. 1980 Nov-Dec; 29(6):515-26.
[Reconstruction of severe loss of mandibular bone substance using metal prostheses].
[A case of mixed tumor of the palate]. Acta Biol Med Ger. 1976 Jul-Sep; 2(3):34.
Farahany NA, Greely HT, Hyman S, Koch C, Grady C, Pa?ca SP, Sestan N, Arlotta P, Bernat JL, Ting J, Lunshof JE, Iyer EPR, Hyun I, Capestany BH, Church GM, Huang H, Song H
The ethics of experimenting with human brain tissue. Nature. 2018 04; 556(7702):429-432.
The ethics of experimenting with human brain tissue.
Cell replacement therapies for nervous system regeneration. Dev Neurobiol. 2012 Feb; 72(2):145-52.
Cell replacement therapies for nervous system regeneration.
Arlotta P, Curci G, Morelli-Coghi A, Pizzoni D
Rassegna internazionale di stomatologia pratica
[Treatment of fracture of the zygomatic arch by means of metallic osteosynthesis]. Rass Int Stomatol Prat. 1972 Nov-Dec; 23(6):189-203.
[Treatment of fracture of the zygomatic arch by means of metallic osteosynthesis].
BioEssays : news and reviews in molecular, cellular and developmental biology
Untangling the cortex: Advances in understanding specification and differentiation of corticospinal motor neurons. Bioessays. 2010 Mar; 32(3):197-206.
Untangling the cortex: Advances in understanding specification and differentiation of corticospinal motor neurons.
Nehme R, Zuccaro E, Ghosh SD, Li C, Sherwood JL, Pietilainen O, Barrett LE, Limone F, Worringer KA, Kommineni S, Zang Y, Cacchiarelli D, Meissner A, Adolfsson R, Haggarty S, Madison J, Muller M, Arlotta P, Fu Z, Feng G, Eggan K
Combining NGN2 Programming with Developmental Patterning Generates Human Excitatory Neurons with NMDAR-Mediated Synaptic Transmission. Cell Rep. 2018 05 22; 23(8):2509-2523.
Combining NGN2 Programming with Developmental Patterning Generates Human Excitatory Neurons with NMDAR-Mediated Synaptic Transmission.
Studying the Brain in a Dish: 3D Cell Culture Models of Human Brain Development and Disease. Curr Top Dev Biol. 2018; 129:99-122.
Studying the Brain in a Dish: 3D Cell Culture Models of Human Brain Development and Disease.
Arlotta P, Molyneaux BJ, Jabaudon D, Yoshida Y, Macklis JD
The Journal of neuroscience : the official journal of the Society for Neuroscience
Ctip2 controls the differentiation of medium spiny neurons and the establishment of the cellular architecture of the striatum. J Neurosci. 2008 Jan 16; 28(3):622-32.
Ctip2 controls the differentiation of medium spiny neurons and the establishment of the cellular architecture of the striatum.
[Gingival hyperplasia due to sodium diphenylhydantoinate]. Riv Ital Stomatol. 1951 Feb; 6(2):180-7.
[Gingival hyperplasia due to sodium diphenylhydantoinate].
ARLOTTA, PAOLA ;SCHINDER, ALEJANDRO FABIAN
Molecular principles of neuronal maturation and integration in the adult and aging brain
[Solitary plasmacytoma of the mandible]. Rass Int Stomatol Prat. 1972 Sep-Oct; 23(5):153-61.
[Solitary plasmacytoma of the mandible].
Developmental Controls are Re-Expressed during Induction of Neurogenesis in the Neocortex of Young Adult Mice. Front Neurosci. 2012; 6:12.
Developmental Controls are Re-Expressed during Induction of Neurogenesis in the Neocortex of Young Adult Mice.
A sip of GABA for the cerebral cortex. Neuron. 2013 Jan 09; 77(1):1-3.
Catapano LA, Arlotta P, Cage TA, Macklis JD
Stage-specific and opposing roles of BDNF, NT-3 and bFGF in differentiation of purified callosal projection neurons toward cellular repair of complex circuitry. Eur J Neurosci. 2004 May; 19(9):2421-34.
Stage-specific and opposing roles of BDNF, NT-3 and bFGF in differentiation of purified callosal projection neurons toward cellular repair of complex circuitry.
Grampa G, Bestetti-Bosisio M, Bergamini F, Arlotta P
A case of Burkitt's tumor in Italy. Pathol Eur. 1970; 5(4):470-84.
Zhang F, Cong L, Lodato S, Kosuri S, Church GM, Arlotta P
Efficient construction of sequence-specific TAL effectors for modulating mammalian transcription. Nat Biotechnol. 2011 Feb; 29(2):149-53.
Efficient construction of sequence-specific TAL effectors for modulating mammalian transcription.
Annals of the New York Academy of Sciences
Induction of adult neurogenesis: molecular manipulation of neural precursors in situ. Ann N Y Acad Sci. 2003 Jun; 991:229-36.
Induction of adult neurogenesis: molecular manipulation of neural precursors in situ.
[Transalveolar route in novocaine analgesia with gelatin sponge in periodontitis]. Minerva Stomatol. 1953 May-Jun; 2(3):141-3.
[Transalveolar route in novocaine analgesia with gelatin sponge in periodontitis].
[Surgical therapy of submandibular sialolithiasis]. Odontostomatol Implantoprotesi. 1975 Jan-Mar; (1):78-81.
[Surgical therapy of submandibular sialolithiasis].
Chau K, Arlotta P, Patel UA, Crane-Robinson C, Manfioletti G, Ono SJ
A novel downstream positive regulatory element mediating transcription of the human high mobility group (HMG) I-C gene. FEBS Lett. 1999 Sep 03; 457(3):429-36.
A novel downstream positive regulatory element mediating transcription of the human high mobility group (HMG) I-C gene.
Molecular development of corticospinal motor neuron circuitry. Novartis Found Symp. 2007; 288:3-15; discussion 15-20, 96-8.
Molecular development of corticospinal motor neuron circuitry.
Professor of Stem Cell and Regenerative Biology
Cell diversity in the human cerebral cortex: from the embryo to brain organoids. Curr Opin Neurobiol. 2019 06; 56:194-198.
Cell diversity in the human cerebral cortex: from the embryo to brain organoids.
Adam Y, Kim JJ, Lou S, Zhao Y, Xie ME, Brinks D, Wu H, Mostajo-Radji MA, Kheifets S, Parot V, Chettih S, Williams KJ, Gmeiner B, Farhi SL, Madisen L, Buchanan EK, Kinsella I, Zhou D, Paninski L, Harvey CD, Zeng H, Arlotta P, Campbell RE, Cohen AE
Voltage imaging and optogenetics reveal behaviour-dependent changes in hippocampal dynamics. Nature. 2019 05; 569(7756):413-417.
Voltage imaging and optogenetics reveal behaviour-dependent changes in hippocampal dynamics.
Jeffrey Daniel Macklis, Dipl.ScNat, Dr.Sc.Tech, M.D.
Max and Anne Wien Professor of Stem Cell and Regenerative Biology
Bullard Professor of Pediatrics and Neurology
Zonouzi M, Berger D, Jokhi V, Kedaigle A, Lichtman J, Arlotta P
Individual Oligodendrocytes Show Bias for Inhibitory Axons in the Neocortex. Cell Rep. 2019 06 04; 27(10):2799-2808.e3.
Individual Oligodendrocytes Show Bias for Inhibitory Axons in the Neocortex.
Velasco S, Kedaigle AJ, Simmons SK, Nash A, Rocha M, Quadrato G, Paulsen B, Nguyen L, Adiconis X, Regev A, Levin JZ, Arlotta P
Individual brain organoids reproducibly form cell diversity of the human cerebral cortex. Nature. 2019 06; 570(7762):523-527.
Individual brain organoids reproducibly form cell diversity of the human cerebral cortex.
John B. Penney, Jr. Professor of Neurology
Bradley John Molyneaux, M.D., M.D.,Ph.D.
Caroline Shields Walker Professor of Medicine
Amamoto R, Zuccaro E, Curry NC, Khurana S, Chen HH, Cepko CL, Arlotta P
FIN-Seq: transcriptional profiling of specific cell types from frozen archived tissue of the human central nervous system. Nucleic Acids Res. 2020 01 10; 48(1):e4.
FIN-Seq: transcriptional profiling of specific cell types from frozen archived tissue of the human central nervous system.
Harris JM, Wang AY, Boulanger-Weill J, Santoriello C, Foianini S, Lichtman JW, Zon LI, Arlotta P
Long-Range Optogenetic Control of Axon Guidance Overcomes Developmental Boundaries and Defects. Dev Cell. 2020 06 08; 53(5):577-588.e7.
Long-Range Optogenetic Control of Axon Guidance Overcomes Developmental Boundaries and Defects.
3D Brain Organoids: Studying Brain Development and Disease Outside the Embryo. Annu Rev Neurosci. 2020 07 08; 43:375-389.
3D Brain Organoids: Studying Brain Development and Disease Outside the Embryo.
Jin X, Simmons SK, Guo A, Shetty AS, Ko M, Nguyen L, Jokhi V, Robinson E, Oyler P, Curry N, Deangeli G, Lodato S, Levin JZ, Regev A, Zhang F, Arlotta P
In vivo Perturb-Seq reveals neuronal and glial abnormalities associated with autism risk genes. Science. 2020 11 27; 370(6520).
In vivo Perturb-Seq reveals neuronal and glial abnormalities associated with autism risk genes.
Albanese A, Swaney JM, Yun DH, Evans NB, Antonucci JM, Velasco S, Sohn CH, Arlotta P, Gehrke L, Chung K
Multiscale 3D phenotyping of human cerebral organoids. Sci Rep. 2020 12 08; 10(1):21487.
Multiscale 3D phenotyping of human cerebral organoids.
Stickels RR, Murray E, Kumar P, Li J, Marshall JL, Di Bella DJ, Arlotta P, Macosko EZ, Chen F
Highly sensitive spatial transcriptomics at near-cellular resolution with Slide-seqV2. Nat Biotechnol. 2021 03; 39(3):313-319.
Highly sensitive spatial transcriptomics at near-cellular resolution with Slide-seqV2.
Yang SM, Michel K, Jokhi V, Nedivi E, Arlotta P
Neuron class-specific responses govern adaptive myelin remodeling in the neocortex. Science. 2020 12 18; 370(6523).
Neuron class-specific responses govern adaptive myelin remodeling in the neocortex.
High throughput assaying of circuit activity and connectivity in brain organoids
Di Bella DJ, Habibi E, Stickels RR, Scalia G, Brown J, Yadollahpour P, Yang SM, Abbate C, Biancalani T, Macosko EZ, Chen F, Regev A, Arlotta P
Molecular logic of cellular diversification in the mouse cerebral cortex. Nature. 2021 07; 595(7868):554-559.
Molecular logic of cellular diversification in the mouse cerebral cortex.
Author Correction: Molecular logic of cellular diversification in the mouse cerebral cortex. Nature. 2021 Aug; 596(7873):E11.
Author Correction: Molecular logic of cellular diversification in the mouse cerebral cortex.
Matho KS, Huilgol D, Galbavy W, He M, Kim G, An X, Lu J, Wu P, Di Bella DJ, Shetty AS, Palaniswamy R, Hatfield J, Raudales R, Narasimhan A, Gamache E, Levine JM, Tucciarone J, Szelenyi E, Harris JA, Mitra PP, Osten P, Arlotta P, Huang ZJ
Genetic dissection of the glutamatergic neuron system in cerebral cortex. Nature. 2021 10; 598(7879):182-187.
Genetic dissection of the glutamatergic neuron system in cerebral cortex.
Optogenetic axon guidance in embryonic zebrafish. STAR Protoc. 2021 12 17; 2(4):100947.
Optogenetic axon guidance in embryonic zebrafish.
Paulsen B, Velasco S, Kedaigle AJ, Pigoni M, Quadrato G, Deo AJ, Adiconis X, Uzquiano A, Sartore R, Yang SM, Simmons SK, Symvoulidis P, Kim K, Tsafou K, Podury A, Abbate C, Tucewicz A, Smith SN, Albanese A, Barrett L, Sanjana NE, Shi X, Chung K, Lage K, Boyden ES, Regev A, Levin JZ, Arlotta P
Autism genes converge on asynchronous development of shared neuron classes. Nature. 2022 02; 602(7896):268-273.
Autism genes converge on asynchronous development of shared neuron classes.
Current opinion in genetics & development
Brain organoids: the quest to decipher human-specific features of brain development. Curr Opin Genet Dev. 2022 08; 75:101955.
Brain organoids: the quest to decipher human-specific features of brain development.
Arlotta P, Chen F, Lodato S, Margrie TW, Nowakowski TJ, Pederson T, Rico B
Dissecting cellular diversity of cortical GABAergic cells across multiple modalities: A turning point in neuronal taxonomy. Fac Rev. 2022; 11:13.
Dissecting cellular diversity of cortical GABAergic cells across multiple modalities: A turning point in neuronal taxonomy.
Uzquiano A, Kedaigle AJ, Pigoni M, Paulsen B, Adiconis X, Kim K, Faits T, Nagaraja S, Antón-Bolaños N, Gerhardinger C, Tucewicz A, Murray E, Jin X, Buenrostro J, Chen F, Velasco S, Regev A, Levin JZ, Arlotta P
Proper acquisition of cell class identity in organoids allows definition of fate specification programs of the human cerebral cortex. Cell. 2022 09 29; 185(20):3770-3788.e27.
Proper acquisition of cell class identity in organoids allows definition of fate specification programs of the human cerebral cortex.
Hyun I, Scharf-Deering JC, Sullivan S, Aach JD, Arlotta P, Baum ML, Church GM, Goldenberg A, Greely HT, Khoshakhlagh P, Kohman RE, Lopes M, Lowenthal C, Lu A, Ng AHM, Pasca SP, Paulsen B, Pigoni M, Scott CT, Silbersweig DA, Skylar-Scott MA, Truog RD, Lunshof JE
How collaboration between bioethicists and neuroscientists can advance research. Nat Neurosci. 2022 11; 25(11):1399-1401.
How collaboration between bioethicists and neuroscientists can advance research.
Yuan W, Ma S, Brown JR, Kim K, Murek V, Trastulla L, Meissner A, Lodato S, Shetty AS, Levin JZ, Buenrostro JD, Ziller MJ, Arlotta P
Temporally divergent regulatory mechanisms govern neuronal diversification and maturation in the mouse and marmoset neocortex. Nat Neurosci. 2022 08; 25(8):1049-1058.
Temporally divergent regulatory mechanisms govern neuronal diversification and maturation in the mouse and marmoset neocortex.
Cable J, Arlotta P, Parker KK, Hughes AJ, Goodwin K, Mummery CL, Kamm RD, Engle SJ, Tagle DA, Boj SF, Stanton AE, Morishita Y, Kemp ML, Norfleet DA, May EE, Lu A, Bashir R, Feinberg AW, Hull SM, Gonzalez AL, Blatchley MR, Montserrat Pulido N, Morizane R, McDevitt TC, Mishra D, Mulero-Russe A
Engineering multicellular living systems-a Keystone Symposia report. Ann N Y Acad Sci. 2022 12; 1518(1):183-195.
Engineering multicellular living systems-a Keystone Symposia report.
Pa?ca SP, Arlotta P, Bateup HS, Camp JG, Cappello S, Gage FH, Knoblich JA, Kriegstein AR, Lancaster MA, Ming GL, Muotri AR, Park IH, Reiner O, Song H, Studer L, Temple S, Testa G, Treutlein B, Vaccarino FM
A nomenclature consensus for nervous system organoids and assembloids. Nature. 2022 09; 609(7929):907-910.
A nomenclature consensus for nervous system organoids and assembloids.
Stogsdill JA, Kim K, Binan L, Farhi SL, Levin JZ, Arlotta P
Pyramidal neuron subtype diversity governs microglia states in the neocortex. Nature. 2022 08; 608(7924):750-756.
Pyramidal neuron subtype diversity governs microglia states in the neocortex.
Susan Solomon. Cell Stem Cell. 2022 Dec 01; 29(12):1619-1620.
Susan L. Solomon (1951-2022): Advocate, Innovator, Catalyst. Stem Cell Reports. 2022 12 13; 17(12):2579-2581.
Susan L. Solomon (1951-2022): Advocate, Innovator, Catalyst.
Neural Organoids and the Quest to Understand and Treat Psychiatric Disease. Biol Psychiatry. 2023 04 01; 93(7):588-589.
Neural Organoids and the Quest to Understand and Treat Psychiatric Disease.
Pigoni M, Uzquiano A, Paulsen B, Kedaigle AJ, Yang SM, Symvoulidis P, Adiconis X, Velasco S, Sartore R, Kim K, Tucewicz A, Tropp SY, Tsafou K, Jin X, Barrett L, Chen F, Boyden ES, Regev A, Levin JZ, Arlotta P
Cell-type specific defects in PTEN-mutant cortical organoids converge on abnormal circuit activity. Hum Mol Genet. 2023 09 05; 32(18):2773-2786.
Cell-type specific defects in PTEN-mutant cortical organoids converge on abnormal circuit activity.
A family portrait of human brain cells. Science. 2023 10 13; 382(6667):168-169.
Waichman TV, Vercesi ML, Berardino AA, Beckel MS, Giacomini D, Rasetto NB, Herrero M, Di Bella DJ, Arlotta P, Schinder AF, Chernomoretz A
scX: A user-friendly tool for scRNA-seq exploration. ArXiv. 2024 Mar 07.
scX: A user-friendly tool for scRNA-seq exploration.
Rasetto NB, Giacomini D, Berardino AA, Waichman TV, Beckel MS, Di Bella DJ, Brown J, Davies-Sala MG, Gerhardinger C, Lie DC, Arlotta P, Chernomoretz A, Schinder AF
bioRxiv : the preprint server for biology
Transcriptional dynamics orchestrating the development and integration of neurons born in the adult hippocampus. bioRxiv. 2024 Jan 11.
Transcriptional dynamics orchestrating the development and integration of neurons born in the adult hippocampus.
scX: a user-friendly tool for scRNAseq exploration. Bioinform Adv. 2024; 4(1):vbae062.
scX: a user-friendly tool for scRNAseq exploration.
Ostrem BEL, Domínguez-Iturza N, Stogsdill JA, Faits T, Kim K, Levin JZ, Arlotta P
Fetal brain response to maternal inflammation requires microglia. Development. 2024 05 15; 151(10).
Fetal brain response to maternal inflammation requires microglia.
Di Bella DJ, Domínguez-Iturza N, Brown JR, Arlotta P
Making Ramón y Cajal proud: Development of cell identity and diversity in the cerebral cortex. Neuron. 2024 Jul 03; 112(13):2091-2111.
Making Ramón y Cajal proud: Development of cell identity and diversity in the cerebral cortex.
Antón-Bolaños N, Faravelli I, Faits T, Andreadis S, Kastli R, Trattaro S, Adiconis X, Wei A, Sampath Kumar A, Di Bella DJ, Tegtmeyer M, Nehme R, Levin JZ, Regev A, Arlotta P
Brain Chimeroids reveal individual susceptibility to neurotoxic triggers. Nature. 2024 07; 631(8019):142-149.
Brain Chimeroids reveal individual susceptibility to neurotoxic triggers.
Transcriptional dynamics orchestrating the development and integration of neurons born in the adult hippocampus. Sci Adv. 2024 07 19; 10(29):eadp6039.
The quest for myelin in the adult brain. Nat Cell Biol. 2013 Jun; 15(6):572-5.
The quest for myelin in the adult brain.
Mangena V, Chanoch-Myers R, Sartore R, Paulsen B, Gritsch S, Weisman H, Hara T, Breakefield XO, Breyne K, Regev A, Chung K, Arlotta P, Tirosh I, Suvà ML
Glioblastoma Cortical Organoids Recapitulate Cell-State Heterogeneity and Intercellular Transfer. Cancer Discov. 2025 Feb 07; 15(2):299-315.
Glioblastoma Cortical Organoids Recapitulate Cell-State Heterogeneity and Intercellular Transfer.
Pa?ca SP, Arlotta P, Bateup HS, Camp JG, Cappello S, Gage FH, Knoblich JA, Kriegstein AR, Lancaster MA, Ming GL, Novarino G, Okano H, Parmar M, Park IH, Reiner O, Song H, Studer L, Takahashi J, Temple S, Testa G, Treutlein B, Vaccarino FM, Vanderhaeghen P, Young-Pearse T
A framework for neural organoids, assembloids and transplantation studies. Nature. 2025 03; 639(8054):315-320.
A framework for neural organoids, assembloids and transplantation studies.
Sauvageau M, Goff LA, Lodato S, Bonev B, Groff AF, Gerhardinger C, Sanchez-Gomez DB, Hacisuleyman E, Li E, Spence M, Liapis SC, Mallard W, Morse M, Swerdel MR, D'Ecclessis MF, Moore JC, Lai V, Gong G, Yancopoulos GD, Frendewey D, Kellis M, Hart RP, Valenzuela DM, Arlotta P, Rinn JL
Multiple knockout mouse models reveal lincRNAs are required for life and brain development. Elife. 2013 Dec 31; 2:e01749.
Multiple knockout mouse models reveal lincRNAs are required for life and brain development.
Fiorenzano A, Sozzi E, Kastli R, Iazzetta MR, Bruzelius A, Arlotta P, Parmar M
Advances, challenges, and opportunities of human midbrain organoids for modelling of the dopaminergic system. EMBO J. 2025 Aug; 44(15):4181-4195.
Advances, challenges, and opportunities of human midbrain organoids for modelling of the dopaminergic system.
Faravelli I, Antón-Bolaños N, Brown JR, Arlotta P
Annual review of genomics and human genetics
Brain Organoids: Tools for Understanding the Uniqueness and Individual Variability of the Human Brain. Annu Rev Genomics Hum Genet. 2025 08; 26(1):299-320.
Brain Organoids: Tools for Understanding the Uniqueness and Individual Variability of the Human Brain.
Pa?ca SP, Arlotta P, Campbell P, Charo A, Evans JH, Farahany N, Gage FH, Godfrey-Smith P, Hyun I, Kriegstein AR, Melloni L, Ming GL, Moreno JD, Sugarman J, Temple S, Testa G, Greely HT
The need for a global effort to attend to human neural organoid and assembloid research. Science. 2025 Nov 06; 390(6773):574-577.
The need for a global effort to attend to human neural organoid and assembloid research.
Faravelli I, Antón-Bolaños N, Wei A, Faits T, Sampath Kumar A, Andreadis S, Kastli R, Montero Crespo M, Steiger M, Leible D, Zhang E, An B, Meirovitch Y, Silwal S, Yang SM, Kovacsovics A, Adiconis X, Kretzmer H, Levin JZ, Boyden ES, Lichtman J, Regev A, Meissner A, Arlotta P
Human brain organoids record the passage of time over multiple years in culture. bioRxiv. 2025 Oct 02.
Human brain organoids record the passage of time over multiple years in culture.
Tomassy GS, Berger DR, Chen HH, Kasthuri N, Hayworth KJ, Vercelli A, Seung HS, Lichtman JW, Arlotta P
Distinct profiles of myelin distribution along single axons of pyramidal neurons in the neocortex. Science. 2014 Apr 18; 344(6181):319-24.
Distinct profiles of myelin distribution along single axons of pyramidal neurons in the neocortex.
Lodato S, Molyneaux BJ, Zuccaro E, Goff LA, Chen HH, Yuan W, Meleski A, Takahashi E, Mahony S, Rinn JL, Gifford DK, Arlotta P
Gene co-regulation by Fezf2 selects neurotransmitter identity and connectivity of corticospinal neurons. Nat Neurosci. 2014 Aug; 17(8):1046-54.
Gene co-regulation by Fezf2 selects neurotransmitter identity and connectivity of corticospinal neurons.
Molyneaux BJ, Goff LA, Brettler AC, Chen HH, Hrvatin S, Rinn JL, Arlotta P
DeCoN: genome-wide analysis of in vivo transcriptional dynamics during pyramidal neuron fate selection in neocortex. Neuron. 2015 Jan 21; 85(2):275-288.
DeCoN: genome-wide analysis of in vivo transcriptional dynamics during pyramidal neuron fate selection in neocortex.
Cerebral cortex assembly: generating and reprogramming projection neuron diversity. Trends Neurosci. 2015 Feb; 38(2):117-25.
Cerebral cortex assembly: generating and reprogramming projection neuron diversity.
Goff LA, Groff AF, Sauvageau M, Trayes-Gibson Z, Sanchez-Gomez DB, Morse M, Martin RD, Elcavage LE, Liapis SC, Gonzalez-Celeiro M, Plana O, Li E, Gerhardinger C, Tomassy GS, Arlotta P, Rinn JL
Proceedings of the National Academy of Sciences of the United States of America
Spatiotemporal expression and transcriptional perturbations by long noncoding RNAs in the mouse brain. Proc Natl Acad Sci U S A. 2015 Jun 02; 112(22):6855-62.
Spatiotemporal expression and transcriptional perturbations by long noncoding RNAs in the mouse brain.
Wiley interdisciplinary reviews. Developmental biology
Building blocks of the cerebral cortex: from development to the dish. Wiley Interdiscip Rev Dev Biol. 2015 Sep-Oct; 4(5):529-44.
Building blocks of the cerebral cortex: from development to the dish.
Ye Z, Mostajo-Radji MA, Brown JR, Rouaux C, Tomassy GS, Hensch TK, Arlotta P
Instructing Perisomatic Inhibition by Direct Lineage Reprogramming of Neocortical Projection Neurons. Neuron. 2015 Nov 04; 88(3):475-83.
Instructing Perisomatic Inhibition by Direct Lineage Reprogramming of Neocortical Projection Neurons.
Diversity Matters: A Revised Guide to Myelination. Trends Cell Biol. 2016 Feb; 26(2):135-147.
Diversity Matters: A Revised Guide to Myelination.
Development-inspired reprogramming of the mammalian central nervous system. Science. 2014 Jan 31; 343(6170):1239882.
Development-inspired reprogramming of the mammalian central nervous system.
Brains in metamorphosis: reprogramming cell identity within the central nervous system. Curr Opin Neurobiol. 2014 Aug; 27:208-14.
Brains in metamorphosis: reprogramming cell identity within the central nervous system.
Reshaping the brain: direct lineage conversion in the nervous system. F1000Prime Rep. 2013 Sep 02; 5:33.
Reshaping the brain: direct lineage conversion in the nervous system.
Smith KA, Arlotta P, Watt FM, Solomon SL
Seven actionable strategies for advancing women in science, engineering, and medicine. Cell Stem Cell. 2015 Mar 05; 16(3):221-4.
Seven actionable strategies for advancing women in science, engineering, and medicine.
Annual review of cell and developmental biology
Generating neuronal diversity in the mammalian cerebral cortex. Annu Rev Cell Dev Biol. 2015; 31:699-720.
Generating neuronal diversity in the mammalian cerebral cortex.
Homeotic Transformations of Neuronal Cell Identities. Trends Neurosci. 2015 Dec; 38(12):751-762.
Homeotic Transformations of Neuronal Cell Identities.
Seq-ing the cortex one neuron at a time. Nat Neurosci. 2016 Feb; 19(2):179-81.
Seq-ing the cortex one neuron at a time.
Stressed out? Healing Tips for Newly Reprogrammed Neurons. Cell Stem Cell. 2016 Mar 03; 18(3):297-9.
Stressed out? Healing Tips for Newly Reprogrammed Neurons.
Amamoto R, Huerta VG, Takahashi E, Dai G, Grant AK, Fu Z, Arlotta P
Adult axolotls can regenerate original neuronal diversity in response to brain injury. Elife. 2016 05 09; 5.
Adult axolotls can regenerate original neuronal diversity in response to brain injury.
Genetic targeting of cortical pyramidal neuron subtypes
Projection neuron control over interneuron positioning into neocortical circuitry
Functional Roles of Long Noncoding RNAs During Neuronal Development
Fate specification of corticospinal neurons by cell autonomous signaling
Genome-wide Light-inducible Tuning of Transcriptional Network Dynamic
Novel epigenetic mechanisms in neuronal development and cognitive function
The promises and challenges of human brain organoids as models of neuropsychiatric disease. Nat Med. 2016 11; 22(11):1220-1228.
The promises and challenges of human brain organoids as models of neuropsychiatric disease.
Editorial overview: Developmental neuroscience 2017. Curr Opin Neurobiol. 2017 02; 42:A1-A4.
Editorial overview: Developmental neuroscience 2017.
[Trichloroethylene in dentin hyperesthesia]. Riv Ital Stomatol. 1951 Sep; 6(9):916-20.
[Trichloroethylene in dentin hyperesthesia].
Star-cross'd neurons: astroglial effects on neural repair in the adult mammalian CNS. Trends Neurosci. 2004 May; 27(5):238-40.
Star-cross'd neurons: astroglial effects on neural repair in the adult mammalian CNS.
Fedoseyeva EV, Boisgérault F, Anosova NG, Wollish WS, Arlotta P, Jensen PE, Ono SJ, Benichou G
Journal of immunology (Baltimore, Md. : 1950)
CD4+ T cell responses to self- and mutated p53 determinants during tumorigenesis in mice. J Immunol. 2000 Jun 01; 164(11):5641-51.
CD4+ T cell responses to self- and mutated p53 determinants during tumorigenesis in mice.
Molyneaux BJ, Arlotta P, Menezes JR, Macklis JD
Neuronal subtype specification in the cerebral cortex. Nat Rev Neurosci. 2007 Jun; 8(6):427-37.
Neuronal subtype specification in the cerebral cortex.
Conditional knock-out of beta-catenin in postnatal-born dentate gyrus granule neurons results in dendritic malformation. J Neurosci. 2007 Dec 26; 27(52):14317-25.
Conditional knock-out of beta-catenin in postnatal-born dentate gyrus granule neurons results in dendritic malformation.
Arlotta P, Rustighi A, Mantovani F, Manfioletti G, Giancotti V, Tell G, Damante G
High mobility group I proteins interfere with the homeodomains binding to DNA. J Biol Chem. 1997 Nov 21; 272(47):29904-10.
High mobility group I proteins interfere with the homeodomains binding to DNA.
[Clinico-statistical study of tumors of the upper jaw]. Riv Ital Stomatol. 1954 May; 9(5):539-50.
[Clinico-statistical study of tumors of the upper jaw].
Tomassy GS, Lodato S, Trayes-Gibson Z, Arlotta P
Development and regeneration of projection neuron subtypes of the cerebral cortex. Sci Prog. 2010; 93(Pt 2):151-69.
Development and regeneration of projection neuron subtypes of the cerebral cortex.
Quadrato G, Nguyen T, Macosko EZ, Sherwood JL, Min Yang S, Berger DR, Maria N, Scholvin J, Goldman M, Kinney JP, Boyden ES, Lichtman JW, Williams ZM, McCarroll SA, Arlotta P
Cell diversity and network dynamics in photosensitive human brain organoids. Nature. 2017 05 04; 545(7652):48-53.
Cell diversity and network dynamics in photosensitive human brain organoids.
Emsley JG, Mitchell BD, Magavi SS, Arlotta P, Macklis JD
NeuroRx : the journal of the American Society for Experimental NeuroTherapeutics
The repair of complex neuronal circuitry by transplanted and endogenous precursors. NeuroRx. 2004 Oct; 1(4):452-71.
The repair of complex neuronal circuitry by transplanted and endogenous precursors.
Lai T, Jabaudon D, Molyneaux BJ, Azim E, Arlotta P, Menezes JR, Macklis JD
SOX5 controls the sequential generation of distinct corticofugal neuron subtypes. Neuron. 2008 Jan 24; 57(2):232-47.
SOX5 controls the sequential generation of distinct corticofugal neuron subtypes.
Mitchell BD, Emsley JG, Magavi SS, Arlotta P, Macklis JD
Constitutive and induced neurogenesis in the adult mammalian brain: manipulation of endogenous precursors toward CNS repair. Dev Neurosci. 2004 Mar-Aug; 26(2-4):101-17.
Constitutive and induced neurogenesis in the adult mammalian brain: manipulation of endogenous precursors toward CNS repair.
Programming and reprogramming neuronal subtypes in the central nervous system. Dev Neurobiol. 2012 Jul; 72(7):1085-98.
Programming and reprogramming neuronal subtypes in the central nervous system.
Lodato S, Tomassy GS, De Leonibus E, Uzcategui YG, Andolfi G, Armentano M, Touzot A, Gaztelu JM, Arlotta P, Menendez de la Prida L, Studer M
Loss of COUP-TFI alters the balance between caudal ganglionic eminence- and medial ganglionic eminence-derived cortical interneurons and results in resistance to epilepsy. J Neurosci. 2011 Mar 23; 31(12):4650-62.
Loss of COUP-TFI alters the balance between caudal ganglionic eminence- and medial ganglionic eminence-derived cortical interneurons and results in resistance to epilepsy.
Direct lineage reprogramming of post-mitotic callosal neurons into corticofugal neurons in vivo. Nat Cell Biol. 2013 Feb; 15(2):214-21.
Direct lineage reprogramming of post-mitotic callosal neurons into corticofugal neurons in vivo.
Kim J, Hughes EG, Shetty AS, Arlotta P, Goff LA, Bergles DE, Brown SP
Changes in the Excitability of Neocortical Neurons in a Mouse Model of Amyotrophic Lateral Sclerosis Are Not Specific to Corticospinal Neurons and Are Modulated by Advancing Disease. J Neurosci. 2017 09 13; 37(37):9037-9053.
Changes in the Excitability of Neocortical Neurons in a Mouse Model of Amyotrophic Lateral Sclerosis Are Not Specific to Corticospinal Neurons and Are Modulated by Advancing Disease.
Molyneaux BJ, Arlotta P, Fame RM, MacDonald JL, MacQuarrie KL, Macklis JD
Novel subtype-specific genes identify distinct subpopulations of callosal projection neurons. J Neurosci. 2009 Sep 30; 29(39):12343-54.
Novel subtype-specific genes identify distinct subpopulations of callosal projection neurons.
Genetic neuroscience: How human genes and alleles shape neuronal phenotypes
A Comprehensive Center for Mouse Brain Cell Atlas
[Xylocaine in use at the Milan Dental Clinic]. Riv Ital Stomatol. 1951 Nov; 6(11):1187-91.
[Xylocaine in use at the Milan Dental Clinic].
Arlotta P, Molyneaux BJ, Chen J, Inoue J, Kominami R, Macklis JD
Neuronal subtype-specific genes that control corticospinal motor neuron development in vivo. Neuron. 2005 Jan 20; 45(2):207-21.
Neuronal subtype-specific genes that control corticospinal motor neuron development in vivo.
Arlotta P, Tai AK, Manfioletti G, Clifford C, Jay G, Ono SJ
Transgenic mice expressing a truncated form of the high mobility group I-C protein develop adiposity and an abnormally high prevalence of lipomas. J Biol Chem. 2000 May 12; 275(19):14394-400.
Transgenic mice expressing a truncated form of the high mobility group I-C protein develop adiposity and an abnormally high prevalence of lipomas.
Fractures of the zygomatic complex. Br J Oral Surg. 1967 Mar; 4(3):192-3.
Arlotta P, Miyazaki D, Copeland NG, Gilbert DJ, Jenkins NA, Ono SJ
Murine NFX.1: isolation and characterization of its messenger RNA, mapping of its chromosomal location and assessment of its developmental expression. Immunology. 2002 Jun; 106(2):173-81.
Murine NFX.1: isolation and characterization of its messenger RNA, mapping of its chromosomal location and assessment of its developmental expression.
Cappello S, Böhringer CR, Bergami M, Conzelmann KK, Ghanem A, Tomassy GS, Arlotta P, Mainardi M, Allegra M, Caleo M, van Hengel J, Brakebusch C, Götz M
A radial glia-specific role of RhoA in double cortex formation. Neuron. 2012 Mar 08; 73(5):911-24.
A radial glia-specific role of RhoA in double cortex formation.
Present and future of modeling human brain development in 3D organoids. Curr Opin Cell Biol. 2017 12; 49:47-52.
Present and future of modeling human brain development in 3D organoids.
Organoids required! A new path to understanding human brain development and disease. Nat Methods. 2018 01 03; 15(1):27-29.
Organoids required! A new path to understanding human brain development and disease.
Fezf2 directs the differentiation of corticofugal neurons from striatal progenitors in vivo. Nat Neurosci. 2010 Nov; 13(11):1345-7.
Fezf2 directs the differentiation of corticofugal neurons from striatal progenitors in vivo.
Lodato S, Rouaux C, Quast KB, Jantrachotechatchawan C, Studer M, Hensch TK, Arlotta P
Excitatory projection neuron subtypes control the distribution of local inhibitory interneurons in the cerebral cortex. Neuron. 2011 Feb 24; 69(4):763-79.
Excitatory projection neuron subtypes control the distribution of local inhibitory interneurons in the cerebral cortex.
Modeling ASD-linked genetic mutations in 3D human brain organoids
Molecular manipulation of neural precursors in situ: induction of adult cortical neurogenesis. Exp Gerontol. 2003 Jan-Feb; 38(1-2):173-82.
Molecular manipulation of neural precursors in situ: induction of adult cortical neurogenesis.
Archeo-cell biology: carbon dating is not just for pots and dinosaurs. Cell. 2005 Jul 15; 122(1):4-6.
Archeo-cell biology: carbon dating is not just for pots and dinosaurs.
Molyneaux BJ, Arlotta P, Hirata T, Hibi M, Macklis JD
Fezl is required for the birth and specification of corticospinal motor neurons. Neuron. 2005 Sep 15; 47(6):817-31.
Fezl is required for the birth and specification of corticospinal motor neurons.