Mitsialis, S. Alex
eCommons Login: SM24
first name: S. Alex
last name: Mitsialis
coauthor of: Kourembanas, Stella
coauthor of: Vitali, Sally Ann
coauthor of: Sun, Ye
coauthor of: Perrella, Mark
coauthor of: Liu, Xiaoli
full name: S. Alex Mitsialis, Ph.D.
has faculty rank: Assistant Professor
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photo: https://connects.catalyst.harvard.edu/Profiles/profile/Modules/CustomViewPersonGeneralInfo/PhotoHandler.ashx
Person ID: 84549
person in primary position: Assistant Professor of Pediatrics
physical neighbor: Chen, Bing
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similar to: Kourembanas, Stella
similar to: Fauza, Dario
similar to: Weissleder, Ralph
similar to: Aikawa, Elena
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selected publications: Authorship 1845121
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selected publications: Authorship 791291
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selected publications: Authorship 133262
selected publications: Authorship 34230
selected publications: Authorship 303304
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selected publications: Authorship 560571
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selected publications: Authorship 197477
selected publications: Authorship 303043
selected publications: Authorship 584173
selected publications: Authorship 610067

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An avian tumor virus promoter directs expression of plasmid genes in Escherichia coli.
PubMed Identifier: 6282693
author list: Mitsialis SA, Young JF, Palese P, Guntaka RV
published in: Gene
information resource reference: An avian tumor virus promoter directs expression of plasmid genes in Escherichia coli. Gene. 1981 Dec; 16(1-3):217-25.
journal title abbreviation: Gene
publication date: 1981-12-01T00:00:00
year: 1981
type: Academic Article
type: Article
type: Document
type: Information Resource

Studies on the developmentally regulated expression and amplification of insect chorion genes.
PubMed Identifier: 3868492
author list: Kafatos FC, Mitsialis SA, Spoerel N, Mariani B, Lingappa JR, Delidakis C
published in: Cold Spring Harbor symposia on quantitative biology
information resource reference: Studies on the developmentally regulated expression and amplification of insect chorion genes. Cold Spring Harb Symp Quant Biol. 1985; 50:537-47.
journal title abbreviation: Cold Spring Harb Symp Quant Biol
publication date: 1985-01-01T00:00:00
year: 1985
type: Academic Article
type: Article
type: Document
type: Information Resource

Mutation of murine adenylate kinase 7 underlies a primary ciliary dyskinesia phenotype.
PubMed Identifier: 18776131
author list: Fernandez-Gonzalez A, Kourembanas S, Wyatt TA, Mitsialis SA
published in: American journal of respiratory cell and molecular biology
information resource reference: Mutation of murine adenylate kinase 7 underlies a primary ciliary dyskinesia phenotype. Am J Respir Cell Mol Biol. 2009 Mar; 40(3):305-13.
journal title abbreviation: Am J Respir Cell Mol Biol
publication date: 2008-09-05T00:00:00
year: 2008
type: Academic Article
type: Article
type: Document
type: Information Resource

Mesenchymal stromal cells expressing heme oxygenase-1 reverse pulmonary hypertension.
PubMed Identifier: 20957739
author list: Liang OD, Mitsialis SA, Chang MS, Vergadi E, Lee C, Aslam M, Fernandez-Gonzalez A, Liu X, Baveja R, Kourembanas S
published in: Stem cells (Dayton, Ohio)
information resource reference: Mesenchymal stromal cells expressing heme oxygenase-1 reverse pulmonary hypertension. Stem Cells. 2011 Jan; 29(1):99-107.
journal title abbreviation: Stem Cells
publication date: 2011-01-01T00:00:00
year: 2011
type: Academic Article
type: Article
type: Document
type: Information Resource

Regulatory elements controlling chorion gene expression are conserved between flies and moths.
PubMed Identifier: 2413366
author list: Mitsialis SA, Kafatos FC
published in: Nature
information resource reference: Regulatory elements controlling chorion gene expression are conserved between flies and moths. Nature. 1985 Oct 3-9; 317(6036):453-6.
journal title abbreviation: Nature
publication date: 1985-10-01T00:00:00
year: 1985
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1061189
type: Authorship
author rank in publication: 8
linked author: Mitsialis, S. Alex
linked information resource: PPAR? agonist pioglitazone reverses pulmonary hypertension and prevents right heart failure via fatty acid oxidation.

PPAR? agonist pioglitazone reverses pulmonary hypertension and prevents right heart failure via fatty acid oxidation.
PubMed Identifier: 29695452
author list: Legchenko E, Chouvarine P, Borchert P, Fernandez-Gonzalez A, Snay E, Meier M, Maegel L, Mitsialis SA, Rog-Zielinska EA, Kourembanas S, Jonigk D, Hansmann G
published in: Science translational medicine
information resource reference: PPAR? agonist pioglitazone reverses pulmonary hypertension and prevents right heart failure via fatty acid oxidation. Sci Transl Med. 2018 04 25; 10(438).
journal title abbreviation: Sci Transl Med
publication date: 2018-04-25T00:00:00
year: 2018
type: Academic Article
type: Article
type: Document
type: Information Resource

Studies on the structure and organization of avian sarcoma proviruses in the rat XC cell line.
PubMed Identifier: 6310031
author list: Mitsialis SA, Katz RA, Svoboda J, Guntaka RV
published in: The Journal of general virology
information resource reference: Studies on the structure and organization of avian sarcoma proviruses in the rat XC cell line. J Gen Virol. 1983 Sep; 64 (Pt 9):1885-93.
journal title abbreviation: J Gen Virol
publication date: 1983-09-01T00:00:00
year: 1983
type: Academic Article
type: Article
type: Document
type: Information Resource

Hypoxia regulates bone morphogenetic protein signaling through C-terminal-binding protein 1.
PubMed Identifier: 16840720
author list: Wu X, Chang MS, Mitsialis SA, Kourembanas S
published in: Circulation research
information resource reference: Hypoxia regulates bone morphogenetic protein signaling through C-terminal-binding protein 1. Circ Res. 2006 Aug 04; 99(3):240-7.
journal title abbreviation: Circ Res
publication date: 2006-07-13T00:00:00
year: 2006
type: Academic Article
type: Article
type: Document
type: Information Resource

A short 5'-flanking DNA region is sufficient for developmentally correct expression of moth chorion genes in Drosophila.
PubMed Identifier: 3120180
author list: Mitsialis SA, Spoerel N, Leviten M, Kafatos FC
published in: Proceedings of the National Academy of Sciences of the United States of America
information resource reference: A short 5'-flanking DNA region is sufficient for developmentally correct expression of moth chorion genes in Drosophila. Proc Natl Acad Sci U S A. 1987 Nov; 84(22):7987-91.
journal title abbreviation: Proc Natl Acad Sci U S A
publication date: 1987-11-01T00:00:00
year: 1987
type: Academic Article
type: Article
type: Document
type: Information Resource

HO-1 mediated cardiac protection in chronic hypoxia: Role of carbon monoxide and bilirubin
author list: Vitali S, Mitsialis SA, Christou H, Kluger M, Liu X, Kourembanas S
information resource reference: HO-1 mediated cardiac protection in chronic hypoxia: Role of carbon monoxide and bilirubin. 2005.
publication date: 2005-01-01T00:00:00
year: 2005
type: Academic Article
type: Article
type: Document
type: Information Resource

Studies on transcriptional control elements within the retroviral long terminal repeat
author list: S. Alex Mitsialis
published in: Studies on transcriptional control elements within the retroviral long terminal repeat.
information resource reference: Studies on transcriptional control elements within the retroviral long terminal repeat. 1983.
publication date: 1983-01-01T00:00:00
year: 1983
type: Academic Article
type: Article
type: Document
type: Information Resource

Developmental control and evolution in the chorion gene families of insects.
PubMed Identifier: 3324698
author list: Kafatos FC, Spoerel N, Mitsialis SA, Nguyen HT, Romano C, Lingappa JR, Mariani BD, Rodakis GC, Lecanidou R, Tsitilou SG
published in: Advances in genetics
information resource reference: Developmental control and evolution in the chorion gene families of insects. Adv Genet. 1987; 24:223-42.
journal title abbreviation: Adv Genet
publication date: 1987-01-01T00:00:00
year: 1987
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1090712
type: Authorship
author rank in publication: 4
linked author: Mitsialis, S. Alex
linked information resource: Macrophage Immunomodulation: The Gatekeeper for Mesenchymal Stem Cell Derived-Exosomes in Pulmonary Arterial Hypertension?

Macrophage Immunomodulation: The Gatekeeper for Mesenchymal Stem Cell Derived-Exosomes in Pulmonary Arterial Hypertension?
PubMed Identifier: 30150544
author list: Willis GR, Fernandez-Gonzalez A, Reis M, Mitsialis SA, Kourembanas S
published in: International journal of molecular sciences
information resource reference: Macrophage Immunomodulation: The Gatekeeper for Mesenchymal Stem Cell Derived-Exosomes in Pulmonary Arterial Hypertension? Int J Mol Sci. 2018 Aug 27; 19(9).
journal title abbreviation: Int J Mol Sci
publication date: 2018-08-27T00:00:00
year: 2018
type: Academic Article
type: Article
type: Document
type: Information Resource

Bone marrow derived mesenchymal stem cells expressing human heme oxygenase-1 (HO-1)reverse hypoxic pulmonary hypertension in HO-1 null mice
author list: Liang OD, Mitsialis SA, Kourembanas S
published in: American Thoracic Society International Conference Proceedings
information resource reference: Bone marrow derived mesenchymal stem cells expressing human heme oxygenase-1 (HO-1)reverse hypoxic pulmonary hypertension in HO-1 null mice. American Thoracic Society International Conference Proceedings. 2006; (3):A25.
publication date: 2006-01-01T00:00:00
year: 2006
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 102717
type: Authorship
author rank in publication: 1
linked author: Mitsialis, S. Alex
linked information resource: An upstream regulatory domain of avian tumor virus long terminal repeat is required for the expression of a procaryotic neomycin gene in eucaryotic cells.

Regulation of Macro-phage Inflammatory Protein – 2 (MIP-2) gene expression by hypoxia
author list: Zampetaki A, Mitsialis, SA, Pfeilschifter, J, and Kourembanas, S.
published in: Am. J. Respir. Crit. Care Med
information resource reference: Regulation of Macro-phage Inflammatory Protein – 2 (MIP-2) gene expression by hypoxia. Am. J. Respir. Crit. Care Med. 2002; A546.
publication date: 2002-01-01T00:00:00
year: 2002
type: Academic Article
type: Article
type: Document
type: Information Resource

Restriction endonuclease and nucleotide sequence analyses of molecularly cloned unintegrated avian tumor virus DNA: structure of large terminal repeats in circle junctions.
PubMed Identifier: 6283156
author list: Katz RA, Omer CA, Weis JH, Mitsialis SA, Faras AJ, Guntaka RV
published in: Journal of virology
information resource reference: Restriction endonuclease and nucleotide sequence analyses of molecularly cloned unintegrated avian tumor virus DNA: structure of large terminal repeats in circle junctions. J Virol. 1982 Apr; 42(1):346-51.
journal title abbreviation: J Virol
publication date: 1982-04-01T00:00:00
year: 1982
type: Academic Article
type: Article
type: Document
type: Information Resource

An upstream regulatory domain of avian tumor virus long terminal repeat is required for the expression of a procaryotic neomycin gene in eucaryotic cells.
PubMed Identifier: 6318077
author list: Mitsialis SA, Caplan S, Guntaka RV
published in: Molecular and cellular biology
information resource reference: An upstream regulatory domain of avian tumor virus long terminal repeat is required for the expression of a procaryotic neomycin gene in eucaryotic cells. Mol Cell Biol. 1983 Nov; 3(11):1975-84.
journal title abbreviation: Mol Cell Biol
publication date: 1983-11-01T00:00:00
year: 1983
type: Academic Article
type: Article
type: Document
type: Information Resource

Cloning of avian tumor virus DNA fragments in plasmid pBR322: evidence for efficient transcription in E. coli from a virus-coded promoter.
PubMed Identifier: 7011902
author list: Guntaka RV, Mitsialis SA
published in: Gene
information resource reference: Cloning of avian tumor virus DNA fragments in plasmid pBR322: evidence for efficient transcription in E. coli from a virus-coded promoter. Gene. 1980 Dec; 12(1-2):113-21.
journal title abbreviation: Gene
publication date: 1980-12-01T00:00:00
year: 1980
type: Academic Article
type: Article
type: Document
type: Information Resource

Targeted expression of heme oxygenase-1 and pulmonary responses to hypoxia
author list: Kourembanas S, Minamino T, Christou H, Hsieh C-M, Liu Y, Dhawan V, Atwater L, Abraham NG, Perella MA and Mitsialis SA.
published in: Heme Oxygenase in Biology and Medicine
information resource reference: Targeted expression of heme oxygenase-1 and pulmonary responses to hypoxia. Heme Oxygenase in Biology and Medicine. 2002; 193-204.
publication date: 2002-01-01T00:00:00
year: 2002
type: Academic Article
type: Article
type: Document
type: Information Resource

Regulation of heme oxygenase-1 (HO-1) gene expression in vascular smooth muscle cells by extracellular acidosis
author list: Christou, H, Mitsialis, SA, Kourembanas, S.
published in: Pediatric Research
information resource reference: Regulation of heme oxygenase-1 (HO-1) gene expression in vascular smooth muscle cells by extracellular acidosis. Pediatric Research. 2003; 53(4):A3220.
publication date: 2003-01-01T00:00:00
year: 2003
type: Academic Article
type: Article
type: Document
type: Information Resource

Mechanisms of heme oxygenase-1-mediated cardiac and pulmonary vascular protection in chronic hypoxia: roles of carbon monoxide and bilirubin.
PubMed Identifier: 16373841
author list: Vitali SH, Mitsialis SA, Christou H, Fernandez-Gonzalez A, Liu X, Kourembanas S
published in: Chest
information resource reference: Mechanisms of heme oxygenase-1-mediated cardiac and pulmonary vascular protection in chronic hypoxia: roles of carbon monoxide and bilirubin. Chest. 2005 Dec; 128(6 Suppl):578S-579S.
journal title abbreviation: Chest
publication date: 2005-12-01T00:00:00
year: 2005
type: Academic Article
type: Article
type: Document
type: Information Resource

Binding of Escherichia coli RNA polymerase to a specific site located near the 3'-end of the avaian sarcoma virus genome.
PubMed Identifier: 6249369
author list: Guntaka RV, Rao PY, Katz RA, Mitsialis SA
published in: Biochimica et biophysica acta
information resource reference: Binding of Escherichia coli RNA polymerase to a specific site located near the 3'-end of the avaian sarcoma virus genome. Biochim Biophys Acta. 1980 May 30; 607(3):457-69.
journal title abbreviation: Biochim Biophys Acta
publication date: 1980-05-30T00:00:00
year: 1980
type: Academic Article
type: Article
type: Document
type: Information Resource

Studies on the methylation of avian sarcoma proviruses in permissive and non-permissive cells.
PubMed Identifier: 6300293
author list: Katz RA, Mitsialis SA, Guntaka RV
published in: The Journal of general virology
information resource reference: Studies on the methylation of avian sarcoma proviruses in permissive and non-permissive cells. J Gen Virol. 1983 Feb; 64 (Pt 2):429-35.
journal title abbreviation: J Gen Virol
publication date: 1983-02-01T00:00:00
year: 1983
type: Academic Article
type: Article
type: Document
type: Information Resource

Effect of heme oxygenase-1 overexpression in two models of lung inflammation.
PubMed Identifier: 12709566
author list: Zampetaki A, Minamino T, Mitsialis SA, Kourembanas S
published in: Experimental biology and medicine (Maywood, N.J.)
information resource reference: Effect of heme oxygenase-1 overexpression in two models of lung inflammation. Exp Biol Med (Maywood). 2003 May; 228(5):442-6.
journal title abbreviation: Exp Biol Med (Maywood)
publication date: 2003-05-01T00:00:00
year: 2003
type: Academic Article
type: Article
type: Document
type: Information Resource

Extracellular acidosis induces heme oxygenase-1 expression in vascular smooth muscle cells.
PubMed Identifier: 15681695
author list: Christou H, Bailey N, Kluger MS, Mitsialis SA, Kourembanas S
published in: American journal of physiology. Heart and circulatory physiology
information resource reference: Extracellular acidosis induces heme oxygenase-1 expression in vascular smooth muscle cells. Am J Physiol Heart Circ Physiol. 2005 Jun; 288(6):H2647-52.
journal title abbreviation: Am J Physiol Heart Circ Physiol
publication date: 2005-01-28T00:00:00
year: 2005
type: Academic Article
type: Article
type: Document
type: Information Resource

Divergent cardiopulmonary actions of heme oxygenase enzymatic products in chronic hypoxia.
PubMed Identifier: 19543386
author list: Vitali SH, Mitsialis SA, Liang OD, Liu X, Fernandez-Gonzalez A, Christou H, Wu X, McGowan FX, Kourembanas S
published in: PloS one
information resource reference: Divergent cardiopulmonary actions of heme oxygenase enzymatic products in chronic hypoxia. PLoS One. 2009 Jun 19; 4(6):e5978.
journal title abbreviation: PLoS One
publication date: 2009-06-19T00:00:00
year: 2009
type: Academic Article
type: Article
type: Document
type: Information Resource

Heme Oxygenase-1 (HO-1) overexpression prevents fibrosis and iron deposition in developmental lung injury
author list: Fernandez-Gonzalez A, Naghshineh S, Mitsialis SA, Kourembanas S.
published in: American Thoracic Society International Conference Proceedings
information resource reference: Heme Oxygenase-1 (HO-1) overexpression prevents fibrosis and iron deposition in developmental lung injury. American Thoracic Society International Conference Proceedings. 2006; (3):A254.
publication date: 2006-01-01T00:00:00
year: 2006
type: Academic Article
type: Article
type: Document
type: Information Resource

Herbimycin and geldanamycin inhibit the hypoxic induction of the vascular endothelial growth factor (VEGF) in pulmonary artery endothelial cells
author list: Brodsky D, Mitsialis SA, Minamino T and Kourembanas S
published in: Pediatric Research 2000
information resource reference: Herbimycin and geldanamycin inhibit the hypoxic induction of the vascular endothelial growth factor (VEGF) in pulmonary artery endothelial cells. Pediatric Research 2000. 2000; 47(4):A380.
publication date: 2000-01-01T00:00:00
year: 2000
type: Academic Article
type: Article
type: Document
type: Information Resource

Hyperoxia
MeSH DescriptorUI: D018496
MeSH semantic group name: Disorders
number of authors: 152
number of publications: 261
uniqueness weight: 0.826937
type: Concept

Mesenchymal Stem Cells
MeSH DescriptorUI: D044982
MeSH semantic group name: Anatomy
number of authors: 715
number of publications: 1759
uniqueness weight: 0.463832
type: Concept

Hypertension, Pulmonary
MeSH DescriptorUI: D006976
MeSH semantic group name: Disorders
number of authors: 631
number of publications: 1730
uniqueness weight: 0.440851
type: Concept

Bronchopulmonary Dysplasia
MeSH DescriptorUI: D001997
MeSH semantic group name: Disorders
number of authors: 155
number of publications: 379
uniqueness weight: 0.719203
type: Concept

Authorship 120565
type: Authorship
author rank in publication: 2
linked author: Mitsialis, S. Alex
linked information resource: Hypoxia induces macrophage inflammatory protein-2 (MIP-2) gene expression in murine macrophages via NF-kappaB: the prominent role of p42/ p44 and PI3 kinase pathways.

Exosomes
MeSH DescriptorUI: D055354
MeSH semantic group name: Anatomy
number of authors: 268
number of publications: 453
uniqueness weight: 0.690804
type: Concept

Authorship 1151982
type: Authorship
author rank in publication: 11
linked author: Mitsialis, S. Alex
linked information resource: Defining mesenchymal stromal cell (MSC)-derived small extracellular vesicles for therapeutic applications.

Defining mesenchymal stromal cell (MSC)-derived small extracellular vesicles for therapeutic applications.
PubMed Identifier: 31069028
author list: Witwer KW, Van Balkom BWM, Bruno S, Choo A, Dominici M, Gimona M, Hill AF, De Kleijn D, Koh M, Lai RC, Mitsialis SA, Ortiz LA, Rohde E, Asada T, Toh WS, Weiss DJ, Zheng L, Giebel B, Lim SK
published in: Journal of extracellular vesicles
information resource reference: Defining mesenchymal stromal cell (MSC)-derived small extracellular vesicles for therapeutic applications. J Extracell Vesicles. 2019; 8(1):1609206.
journal title abbreviation: J Extracell Vesicles
publication date: 2019-04-29T00:00:00
year: 2019
type: Academic Article
type: Article
type: Document
type: Information Resource

Anaesthesia
type: Department
type: Organization

Medicine
type: Department
type: Organization

Neurology
type: Department
type: Organization

Ophthalmology
type: Department
type: Organization

Pediatrics
type: Department
type: Organization

Radiology
type: Department
type: Organization

Surgery
type: Department
type: Organization

Cardiology
type: Division
type: Organization

Molecular Medicine
type: Division
type: Organization

Genetics
type: Division
type: Organization

Infectious Disease
type: Division
type: Organization

Pulmonary
type: Division
type: Organization

Brigham and Women's Hospital
type: Organization

Boston Children's Hospital
type: Organization

Massachusetts General Hospital
type: Organization

Chen, Bing
eCommons Login: BC9
first name: Bing
last name: Chen
full name: Bing Chen, Ph.D.
has faculty rank: Full Professor
latitude: 42.33790000000000
longitude: -71.10590000000000
Person ID: 17396
person in primary position: Rosalind Franklin, PhD Professor of Pediatrics
type: Agent
type: Person
preferred title: Rosalind Franklin, PhD Professor of Pediatrics

Aikawa, Elena
eCommons Login: ER4
first name: Elena
last name: Aikawa
full name: Elena Aikawa, M.D., Ph.D.
has faculty rank: Full Professor
latitude: 42.33837200000000
longitude: -71.10326900000000
photo: https://connects.catalyst.harvard.edu/Profiles/profile/Modules/CustomViewPersonGeneralInfo/PhotoHandler.ashx
Person ID: 79704
person in primary position: Professor of Medicine
type: Agent
type: Person
preferred title: Professor of Medicine

Gussoni, Emanuela
eCommons Login: EG9
first name: Emanuela
last name: Gussoni
full name: Emanuela Gussoni, Ph.D.
has faculty rank: Associate Professor
latitude: 42.33790000000000
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Breakefield, Xandra
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Liu, Xiaoli
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Sun, Ye
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Choe, Hyeryun
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Park, Pyong
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Perrella, Mark
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Kunkel, Louis
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Weissleder, Ralph
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Kourembanas, Stella
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Vitali, Sally Ann
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Fauza, Dario
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Mesenchymal stromal cell exosomes prevent and revert experimental pulmonary fibrosis through modulation of monocyte phenotypes.
PubMed Identifier: 31581150
author list: Mansouri N, Willis GR, Fernandez-Gonzalez A, Reis M, Nassiri S, Mitsialis SA, Kourembanas S
published in: JCI insight
information resource reference: Mesenchymal stromal cell exosomes prevent and revert experimental pulmonary fibrosis through modulation of monocyte phenotypes. JCI Insight. 2019 11 01; 4(21).
journal title abbreviation: JCI Insight
publication date: 2019-11-01T00:00:00
year: 2019
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1201471
type: Authorship
author rank in publication: 6
linked author: Mitsialis, S. Alex
linked information resource: Mesenchymal stromal cell exosomes prevent and revert experimental pulmonary fibrosis through modulation of monocyte phenotypes.

Authorship 1201189
type: Authorship
author rank in publication: 6
linked author: Mitsialis, S. Alex
linked information resource: Heme oxygenase-1 dampens the macrophage sterile inflammasome response and regulates its components in the hypoxic lung.

Heme oxygenase-1 dampens the macrophage sterile inflammasome response and regulates its components in the hypoxic lung.
PubMed Identifier: 31664855
author list: Vitali SH, Fernandez-Gonzalez A, Nadkarni J, Kwong A, Rose C, Mitsialis SA, Kourembanas S
published in: American journal of physiology. Lung cellular and molecular physiology
information resource reference: Heme oxygenase-1 dampens the macrophage sterile inflammasome response and regulates its components in the hypoxic lung. Am J Physiol Lung Cell Mol Physiol. 2020 01 01; 318(1):L125-L134.
journal title abbreviation: Am J Physiol Lung Cell Mol Physiol
publication date: 2019-10-30T00:00:00
year: 2019
type: Academic Article
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Professor of Neurology
is primary position: true
position in department: Neurology
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HR job title: Professor of Neurology
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Authorship 1208026
type: Authorship
author rank in publication: 1
linked author: Mitsialis, S. Alex
linked information resource: The Unsettling Ambiguity of Therapeutic Extracellular Vesicles from Mesenchymal Stromal Cells.

The Unsettling Ambiguity of Therapeutic Extracellular Vesicles from Mesenchymal Stromal Cells.
PubMed Identifier: 31805239
author list: Mitsialis SA
published in: American journal of respiratory cell and molecular biology
information resource reference: The Unsettling Ambiguity of Therapeutic Extracellular Vesicles from Mesenchymal Stromal Cells. Am J Respir Cell Mol Biol. 2020 05; 62(5):539-540.
journal title abbreviation: Am J Respir Cell Mol Biol
publication date: 2020-05-01T00:00:00
year: 2020
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 133262
type: Authorship
author rank in publication: 8
linked author: Mitsialis, S. Alex
linked information resource: Improved pulmonary vascular reactivity and decreased hypertrophic remodeling during nonhypercapnic acidosis in experimental pulmonary hypertension.

Authorship 197477
type: Authorship
author rank in publication: 3
linked author: Mitsialis, S. Alex
linked information resource: The role of heme oxygenase-1 in pulmonary disease.

Authorship 1248228
type: Authorship
author rank in publication: 16
linked author: Mitsialis, S. Alex
linked information resource: https://connects.catalyst.harvard.edu/Profiles/profile/153504439

https://connects.catalyst.harvard.edu/Profiles/profile/153504439
PubMed Identifier: 32425691
author list: Börger V, Weiss DJ, Anderson JD, Borràs FE, Bussolati B, Carter DRF, Dominici M, Falcón-Pérez JM, Gimona M, Hill AF, Hoffman AM, de Kleijn D, Levine BL, Lim R, Lötvall J, Mitsialis SA, Monguió-Tortajada M, Muraca M, Nieuwland R, Nowocin A, O'Driscoll L, Ortiz LA, Phinney DG, Reischl I, Rohde E, Sanzenbacher R, Théry C, Toh WS, Witwer KW, Lim SK, Giebel B
published in: Cytotherapy
information resource reference: International Society for Extracellular Vesicles and International Society for Cell and Gene Therapy statement on extracellular vesicles from mesenchymal stromal cells and other cells: considerations for potential therapeutic agents to suppress coronavirus disease-19. Cytotherapy. 2020 09; 22(9):482-485.
journal title abbreviation: Cytotherapy
publication date: 2020-05-16T00:00:00
year: 2020
type: Academic Article
type: Article
type: Document
type: Information Resource
label: International Society for Extracellular Vesicles and International Society for Cell and Gene Therapy statement on extracellular vesicles from mesenchymal stromal cells and other cells: considerations for potential therapeutic agents to suppress coronavirus disease-19.

Authorship 132547
type: Authorship
author rank in publication: 3
linked author: Mitsialis, S. Alex
linked information resource: Isolation and characterization of cDNA clones encoding human liver glutamate dehydrogenase: evidence for a small gene family.

Authorship 1284659
type: Authorship
author rank in publication: 8
linked author: Mitsialis, S. Alex
linked information resource: Mesenchymal stromal cell-derived small extracellular vesicles restore lung architecture and improve exercise capacity in a model of neonatal hyperoxia-induced lung injury.

Mesenchymal stromal cell-derived small extracellular vesicles restore lung architecture and improve exercise capacity in a model of neonatal hyperoxia-induced lung injury.
PubMed Identifier: 32939235
author list: Willis GR, Fernandez-Gonzalez A, Reis M, Yeung V, Liu X, Ericsson M, Andrews NA, Mitsialis SA, Kourembanas S
published in: Journal of extracellular vesicles
information resource reference: Mesenchymal stromal cell-derived small extracellular vesicles restore lung architecture and improve exercise capacity in a model of neonatal hyperoxia-induced lung injury. J Extracell Vesicles. 2020 Jul 13; 9(1):1790874.
journal title abbreviation: J Extracell Vesicles
publication date: 2020-07-13T00:00:00
year: 2020
type: Academic Article
type: Article
type: Document
type: Information Resource

Mesenchymal stromal cell-derived extracellular vesicle therapy prevents preeclamptic physiology through intrauterine immunomodulation†.
PubMed Identifier: 33112369
author list: Taglauer ES, Fernandez-Gonzalez A, Willis GR, Reis M, Yeung V, Liu X, Mitsialis SA, Kourembanas S
published in: Biology of reproduction
information resource reference: Mesenchymal stromal cell-derived extracellular vesicle therapy prevents preeclamptic physiology through intrauterine immunomodulation†. Biol Reprod. 2021 02 11; 104(2):457-467.
journal title abbreviation: Biol Reprod
publication date: 2021-02-11T00:00:00
year: 2021
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1299708
type: Authorship
author rank in publication: 7
linked author: Mitsialis, S. Alex
linked information resource: Mesenchymal stromal cell-derived extracellular vesicle therapy prevents preeclamptic physiology through intrauterine immunomodulation†.

Authorship 1345134
type: Authorship
author rank in publication: 6
linked author: Mitsialis, S. Alex
linked information resource: Therapeutic Effects of Mesenchymal Stromal Cell-Derived Small Extracellular Vesicles in Oxygen-Induced Multi-Organ Disease: A Developmental Perspective.

Therapeutic Effects of Mesenchymal Stromal Cell-Derived Small Extracellular Vesicles in Oxygen-Induced Multi-Organ Disease: A Developmental Perspective.
PubMed Identifier: 33796534
author list: Fernandez-Gonzalez A, Willis GR, Yeung V, Reis M, Liu X, Mitsialis SA, Kourembanas S
published in: Frontiers in cell and developmental biology
information resource reference: Therapeutic Effects of Mesenchymal Stromal Cell-Derived Small Extracellular Vesicles in Oxygen-Induced Multi-Organ Disease: A Developmental Perspective. Front Cell Dev Biol. 2021; 9:647025.
journal title abbreviation: Front Cell Dev Biol
publication date: 2021-03-16T00:00:00
year: 2021
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 145970
type: Authorship
author rank in publication: 4
linked author: Mitsialis, S. Alex
linked information resource: Extracellular acidosis induces heme oxygenase-1 expression in vascular smooth muscle cells.

Authorship 162358
type: Authorship
author rank in publication: 3
linked author: Mitsialis, S. Alex
linked information resource: Modification of avian sarcoma proviral DNA sequences in nonpermissive XC cells but not in permissive chicken cells.

Authorship 1352415
type: Authorship
author rank in publication: 12
linked author: Mitsialis, S. Alex
linked information resource: Mesenchymal Stromal Cell-Derived Extracellular Vesicles Restore Thymic Architecture and T Cell Function Disrupted by Neonatal Hyperoxia.

Mesenchymal Stromal Cell-Derived Extracellular Vesicles Restore Thymic Architecture and T Cell Function Disrupted by Neonatal Hyperoxia.
PubMed Identifier: 33936055
author list: Reis M, Willis GR, Fernandez-Gonzalez A, Yeung V, Taglauer E, Magaletta M, Parsons T, Derr A, Liu X, Maehr R, Kourembanas S, Mitsialis SA
published in: Frontiers in immunology
information resource reference: Mesenchymal Stromal Cell-Derived Extracellular Vesicles Restore Thymic Architecture and T Cell Function Disrupted by Neonatal Hyperoxia. Front Immunol. 2021; 12:640595.
journal title abbreviation: Front Immunol
publication date: 2021-04-15T00:00:00
year: 2021
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 254255
type: Authorship
author rank in publication: 1
linked author: Mitsialis, S. Alex
linked information resource: A short 5'-flanking DNA region is sufficient for developmentally correct expression of moth chorion genes in Drosophila.

Authorship 174318
type: Authorship
author rank in publication: 2
linked author: Mitsialis, S. Alex
linked information resource: Retinoic acid alters the expression of pattern-related genes in the developing rat lung.

Authorship 1381680
type: Authorship
author rank in publication: 14
linked author: Mitsialis, S. Alex
linked information resource: Mesenchymal stromal cell-derived syndecan-2 regulates the immune response during sepsis to foster bacterial clearance and resolution of inflammation.

Mesenchymal stromal cell-derived syndecan-2 regulates the immune response during sepsis to foster bacterial clearance and resolution of inflammation.
PubMed Identifier: 34355516
author list: Han J, Shi Y, Willis G, Imani J, Kwon MY, Li G, Ayaub E, Ghanta S, Ng J, Hwang N, Tsoyi K, El-Chemaly S, Kourembanas S, Mitsialis SA, Rosas IO, Liu X, Perrella MA
published in: The FEBS journal
information resource reference: Mesenchymal stromal cell-derived syndecan-2 regulates the immune response during sepsis to foster bacterial clearance and resolution of inflammation. FEBS J. 2022 01; 289(2):417-435.
journal title abbreviation: FEBS J
publication date: 2021-08-15T00:00:00
year: 2021
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1389673
type: Authorship
author rank in publication: 10
linked author: Mitsialis, S. Alex
linked information resource: Intratracheal transplantation of trophoblast stem cells attenuates acute lung injury in mice.

Intratracheal transplantation of trophoblast stem cells attenuates acute lung injury in mice.
PubMed Identifier: 34461993
author list: Han J, Li G, Hou M, Ng J, Kwon MY, Xiong K, Liang X, Taglauer E, Shi Y, Mitsialis SA, Kourembanas S, El-Chemaly S, Lederer JA, Rosas IO, Perrella MA, Liu X
published in: Stem cell research & therapy
information resource reference: Intratracheal transplantation of trophoblast stem cells attenuates acute lung injury in mice. Stem Cell Res Ther. 2021 08 30; 12(1):487.
journal title abbreviation: Stem Cell Res Ther
publication date: 2021-08-30T00:00:00
year: 2021
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1400433
type: Authorship
author rank in publication: 8
linked author: Mitsialis, S. Alex
linked information resource: Antenatal Mesenchymal Stromal Cell Extracellular Vesicle Therapy Prevents Preeclamptic Lung Injury in Mice.

Antenatal Mesenchymal Stromal Cell Extracellular Vesicle Therapy Prevents Preeclamptic Lung Injury in Mice.
PubMed Identifier: 34614384
author list: Taglauer ES, Fernandez-Gonzalez A, Willis GR, Reis M, Yeung V, Liu X, Prince LS, Mitsialis SA, Kourembanas S
published in: American journal of respiratory cell and molecular biology
information resource reference: Antenatal Mesenchymal Stromal Cell Extracellular Vesicle Therapy Prevents Preeclamptic Lung Injury in Mice. Am J Respir Cell Mol Biol. 2022 01; 66(1):86-95.
journal title abbreviation: Am J Respir Cell Mol Biol
publication date: 2022-01-01T00:00:00
year: 2022
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1405644
type: Authorship
author rank in publication: 10
linked author: Mitsialis, S. Alex
linked information resource: Extracellular Vesicles Protect the Neonatal Lung from Hyperoxic Injury through the Epigenetic and Transcriptomic Reprogramming of Myeloid Cells.

Extracellular Vesicles Protect the Neonatal Lung from Hyperoxic Injury through the Epigenetic and Transcriptomic Reprogramming of Myeloid Cells.
PubMed Identifier: 34699335
author list: Willis GR, Reis M, Gheinani AH, Fernandez-Gonzalez A, Taglauer ES, Yeung V, Liu X, Ericsson M, Haas E, Mitsialis SA, Kourembanas S
published in: American journal of respiratory and critical care medicine
information resource reference: Extracellular Vesicles Protect the Neonatal Lung from Hyperoxic Injury through the Epigenetic and Transcriptomic Reprogramming of Myeloid Cells. Am J Respir Crit Care Med. 2021 12 15; 204(12):1418-1432.
journal title abbreviation: Am J Respir Crit Care Med
publication date: 2021-12-15T00:00:00
year: 2021
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1418161
type: Authorship
author rank in publication: 7
linked author: Mitsialis, S. Alex
linked information resource: Antenatal mesenchymal stromal cell extracellular vesicle treatment preserves lung development in a model of bronchopulmonary dysplasia due to chorioamnionitis.

Antenatal mesenchymal stromal cell extracellular vesicle treatment preserves lung development in a model of bronchopulmonary dysplasia due to chorioamnionitis.
PubMed Identifier: 34878940
author list: Abele AN, Taglauer ES, Almeda M, Wilson N, Abikoye A, Seedorf GJ, Mitsialis SA, Kourembanas S, Abman SH
published in: American journal of physiology. Lung cellular and molecular physiology
information resource reference: Antenatal mesenchymal stromal cell extracellular vesicle treatment preserves lung development in a model of bronchopulmonary dysplasia due to chorioamnionitis. Am J Physiol Lung Cell Mol Physiol. 2022 02 01; 322(2):L179-L190.
journal title abbreviation: Am J Physiol Lung Cell Mol Physiol
publication date: 2021-12-08T00:00:00
year: 2021
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1479643
type: Authorship
linked author: Mitsialis, S. Alex
linked information resource: Mesenchymal Stromal/Stem Cell Extracellular Vesicles and Perinatal Injury: One Formula for Many Diseases.

Mesenchymal Stromal/Stem Cell Extracellular Vesicles and Perinatal Injury: One Formula for Many Diseases.
PubMed Identifier: 36044737
author list: Delavogia E, Ntentakis DP, Cortinas JA, Fernandez-Gonzalez A, Alex Mitsialis S, Kourembanas S
published in: Stem cells (Dayton, Ohio)
information resource reference: Mesenchymal Stromal/Stem Cell Extracellular Vesicles and Perinatal Injury: One Formula for Many Diseases. Stem Cells. 2022 11 29; 40(11):991-1007.
journal title abbreviation: Stem Cells
publication date: 2022-11-29T00:00:00
year: 2022
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 197993
type: Authorship
author rank in publication: 2
linked author: Mitsialis, S. Alex
linked information resource: Studies on the methylation of avian sarcoma proviruses in permissive and non-permissive cells.

Assistant Professor of Medicine
is primary position: true
position in department: Medicine
position in division: Pulmonary
sort order: 1
type: Position
HR job title: Assistant Professor of Medicine
position in organization: Brigham and Women's Hospital

Authorship 1552254
type: Authorship
author rank in publication: 4
linked author: Mitsialis, S. Alex
linked information resource: Harnessing the therapeutic potential of the stem cell secretome in neonatal diseases.

Harnessing the therapeutic potential of the stem cell secretome in neonatal diseases.
PubMed Identifier: 36990921
author list: Tung S, Delavogia E, Fernandez-Gonzalez A, Mitsialis SA, Kourembanas S
published in: Seminars in perinatology
information resource reference: Harnessing the therapeutic potential of the stem cell secretome in neonatal diseases. Semin Perinatol. 2023 04; 47(3):151730.
journal title abbreviation: Semin Perinatol
publication date: 2023-03-12T00:00:00
year: 2023
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1584729
type: Authorship
author rank in publication: 10
linked author: Mitsialis, S. Alex
linked information resource: Immunoregulatory macrophages modify local pulmonary immunity and ameliorate hypoxic-pulmonary hypertension.

Immunoregulatory macrophages modify local pulmonary immunity and ameliorate hypoxic-pulmonary hypertension.
PubMed Identifier: 37577587
author list: Fernandez-Gonzalez A, Mukhia A, Nadkarni J, Willis GR, Reis M, Zhumka K, Vitali S, Liu X, Galls A, Mitsialis SA, Kourembanas S
published in: bioRxiv : the preprint server for biology
information resource reference: Immunoregulatory macrophages modify local pulmonary immunity and ameliorate hypoxic-pulmonary hypertension. bioRxiv. 2023 Aug 02.
journal title abbreviation: bioRxiv
publication date: 2023-08-02T00:00:00
year: 2023
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 452033
type: Authorship
author rank in publication: 2
linked author: Mitsialis, S. Alex
linked information resource: Exosomes mediate the cytoprotective action of mesenchymal stromal cells on hypoxia-induced pulmonary hypertension.

Professor of Medicine
is primary position: true
position in department: Medicine
position in division: Cardiology
sort order: 1
type: Position
HR job title: Professor of Medicine
position in organization: Brigham and Women's Hospital

Authorship 1637779
type: Authorship
author rank in publication: 11
linked author: Mitsialis, S. Alex
linked information resource: Photoreceptors inhibit pathological retinal angiogenesis through transcriptional regulation of Adam17 via c-Fos.

Authorship 1639817
type: Authorship
author rank in publication: 10
linked author: Mitsialis, S. Alex
linked information resource: SOCS3 regulates pathological retinal angiogenesis through modulating SPP1 expression in microglia and macrophages.

Photoreceptors inhibit pathological retinal angiogenesis through transcriptional regulation of Adam17 via c-Fos.
PubMed Identifier: 38483712
author list: Wang X, Wang T, Kaneko S, Kriukov E, Lam E, Szczepan M, Chen J, Gregg A, Wang X, Fernandez-Gonzalez A, Mitsialis SA, Kourembanas S, Baranov P, Sun Y
published in: Angiogenesis
information resource reference: Photoreceptors inhibit pathological retinal angiogenesis through transcriptional regulation of Adam17 via c-Fos. Angiogenesis. 2024 Aug; 27(3):379-395.
journal title abbreviation: Angiogenesis
publication date: 2024-03-14T00:00:00
year: 2024
type: Academic Article
type: Article
type: Document
type: Information Resource

SOCS3 regulates pathological retinal angiogenesis through modulating SPP1 expression in microglia and macrophages.
PubMed Identifier: 38504518
author list: Wang T, Kaneko S, Kriukov E, Alvarez D, Lam E, Wang Y, La Manna S, Marasco D, Fernandez-Gonzalez A, Mitsialis SA, Kourembanas S, Stahl A, Chen M, Xu H, Baranov P, Cai G, von Andrian UH, Sun Y
published in: Molecular therapy : the journal of the American Society of Gene Therapy
information resource reference: SOCS3 regulates pathological retinal angiogenesis through modulating SPP1 expression in microglia and macrophages. Mol Ther. 2024 May 01; 32(5):1425-1444.
journal title abbreviation: Mol Ther
publication date: 2024-03-19T00:00:00
year: 2024
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1641830
type: Authorship
author rank in publication: 21
linked author: Mitsialis, S. Alex
linked information resource: Mesenchymal stromal cell extracellular vesicles improve lung development in mechanically ventilated preterm lambs.

Mesenchymal stromal cell extracellular vesicles improve lung development in mechanically ventilated preterm lambs.
PubMed Identifier: 38563994
author list: Albertine KH, Rebentisch A, Dawson E, Van Boerum J, Major E, Štipka J, Foreman H, Headden D, Vordos Z, Beck E, Wang Z, Yang H, Yu B, Dahl MJ, Null DM, Bizzotto D, Veneroni C, Lavizzari A, Dellacà RL, Delavogia E, Mitsialis SA, Kourembanas S
published in: American journal of physiology. Lung cellular and molecular physiology
information resource reference: Mesenchymal stromal cell extracellular vesicles improve lung development in mechanically ventilated preterm lambs. Am J Physiol Lung Cell Mol Physiol. 2024 Jun 01; 326(6):L770-L785.
journal title abbreviation: Am J Physiol Lung Cell Mol Physiol
publication date: 2024-04-02T00:00:00
year: 2024
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 599639
type: Authorship
linked author: Mitsialis, S. Alex
linked information resource: Heme Oxygenase and pulmonary responses to hypoxia

Authorship 303043
type: Authorship
author rank in publication: 3
linked author: Mitsialis, S. Alex
linked information resource: Hypoxia regulates bone morphogenetic protein signaling through C-terminal-binding protein 1.

Associate Professor of Medicine
is primary position: true
position in department: Medicine
position in division: Pulmonary
sort order: 1
type: Position
HR job title: Associate Professor of Medicine
position in organization: Brigham and Women's Hospital

Thrall Family Professor of Radiology
is primary position: true
position in department: Radiology
position in division: https://connects.catalyst.harvard.edu/Profiles/profile/1229413
sort order: 1
type: Position
HR job title: Thrall Family Professor of Radiology
position in organization: Massachusetts General Hospital

Authorship 651168
type: Authorship
author rank in publication: 5
linked author: Mitsialis, S. Alex
linked information resource: Endothelial indoleamine 2,3-dioxygenase protects against development of pulmonary hypertension.

Endothelial indoleamine 2,3-dioxygenase protects against development of pulmonary hypertension.
PubMed Identifier: 23822766
author list: Xiao Y, Christou H, Liu L, Visner G, Mitsialis SA, Kourembanas S, Liu H
published in: American journal of respiratory and critical care medicine
information resource reference: Endothelial indoleamine 2,3-dioxygenase protects against development of pulmonary hypertension. Am J Respir Crit Care Med. 2013 Aug 15; 188(4):482-91.
journal title abbreviation: Am J Respir Crit Care Med
publication date: 2013-08-15T00:00:00
year: 2013
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1695946
type: Authorship
author rank in publication: 10
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linked information resource: Immunoregulatory Macrophages Modify Local Pulmonary Immunity and Ameliorate Hypoxic Pulmonary Hypertension.

Immunoregulatory Macrophages Modify Local Pulmonary Immunity and Ameliorate Hypoxic Pulmonary Hypertension.
PubMed Identifier: 39387119
author list: Fernandez-Gonzalez A, Mukhia A, Nadkarni J, Willis GR, Reis M, Zhumka K, Vitali S, Liu X, Galls A, Mitsialis SA, Kourembanas S
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Authorship 63070
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linked information resource: Restriction endonuclease and nucleotide sequence analyses of molecularly cloned unintegrated avian tumor virus DNA: structure of large terminal repeats in circle junctions.

Authorship 604433
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linked information resource: Regulation of heme oxygenase-1 (HO-1) gene expression in vascular smooth muscle cells by extracellular acidosis

Authorship 219120
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linked information resource: Regulatory elements controlling chorion gene expression are conserved between flies and moths.

Authorship 1845121
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linked information resource: Mouse radial spoke 3 is a metabolic and regulatory hub in cilia.

Authorship 1844306
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linked information resource: The cryo-EM structure of mouse radial spoke 3 reveals a unique metabolic and regulatory hub in cilia.

The cryo-EM structure of mouse radial spoke 3 reveals a unique metabolic and regulatory hub in cilia.
PubMed Identifier: 40475651
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Mouse radial spoke 3 is a metabolic and regulatory hub in cilia.
PubMed Identifier: 40579595
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Newborn Medicine
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Authorship 351992
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linked author: Mitsialis, S. Alex
linked information resource: Mesenchymal stem cell-mediated reversal of bronchopulmonary dysplasia and associated pulmonary hypertension.

Authorship 34230
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linked information resource: Early macrophage recruitment and alternative activation are critical for the later development of hypoxia-induced pulmonary hypertension.

Professor of Pediatrics
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Assistant Professor of Anaesthesia
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Rosalind Franklin, PhD Professor of Pediatrics
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Professor of Pediatrics
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Associate Professor of Surgery
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Associate Professor of Ophthalmology
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position in division: https://connects.catalyst.harvard.edu/Profiles/profile/1229413
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Clement A. Smith Professor of Pediatrics
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Assistant Professor of Pediatrics
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Associate Professor of Pediatrics
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position in division: Genetics
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Professor of Pediatrics
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position in division: Genetics
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Authorship 324446
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author rank in publication: 10
linked author: Mitsialis, S. Alex
linked information resource: Absence of cyclooxygenase-2 exacerbates hypoxia-induced pulmonary hypertension and enhances contractility of vascular smooth muscle cells.

Authorship 755981
type: Authorship
author rank in publication: 9
linked author: Mitsialis, S. Alex
linked information resource: An Argonaute 2 switch regulates circulating miR-210 to coordinate hypoxic adaptation across cells.

An Argonaute 2 switch regulates circulating miR-210 to coordinate hypoxic adaptation across cells.
PubMed Identifier: 24983771
author list: Hale A, Lee C, Annis S, Min PK, Pande R, Creager MA, Julian CG, Moore LG, Mitsialis SA, Hwang SJ, Kourembanas S, Chan SY
published in: Biochimica et biophysica acta
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Authorship 85801
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linked information resource: Transgenic regulation of moth chorion gene promoters in Drosophila: tissue, temporal, and quantitative control of four bidirectional promoters.

Authorship 582297
type: Authorship
linked author: Mitsialis, S. Alex
linked information resource: Studies on transcriptional control elements within the retroviral long terminal repeat

Authorship 599092
type: Authorship
linked author: Mitsialis, S. Alex
linked information resource: HO-1 mediated cardiac protection in chronic hypoxia: Role of carbon monoxide and bilirubin

Authorship 60602
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linked author: Mitsialis, S. Alex
linked information resource: Regulation of renal rK1-kallikrein in spontaneously hypertensive rats.

Authorship 618435
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linked information resource: Regulation of Macro-phage Inflammatory Protein – 2 (MIP-2) gene expression by hypoxia

Authorship 89007
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author rank in publication: 4
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linked information resource: Mutation of murine adenylate kinase 7 underlies a primary ciliary dyskinesia phenotype.

Authorship 206501
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author rank in publication: 1
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linked information resource: An avian tumor virus promoter directs expression of plasmid genes in Escherichia coli.

Authorship 218301
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author rank in publication: 7
linked author: Mitsialis, S. Alex
linked information resource: DNA binding and heteromerization of the Drosophila transcription factor chorion factor 1/ultraspiracle.

Authorship 428214
type: Authorship
author rank in publication: 1
linked author: Mitsialis, S. Alex
linked information resource: Localization of active promoters for eucaryotic RNA polymerase II in the long terminal repeat of avian sarcoma virus DNA.

Authorship 472800
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linked author: Mitsialis, S. Alex
linked information resource: Developmental control and evolution in the chorion gene families of insects.

Authorship 584173
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linked information resource: Heme Oxygenase-1 (HO-1) overexpression prevents fibrosis and iron deposition in developmental lung injury

Authorship 611695
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linked information resource: Bone marrow derived mesenchymal stem cells expressing human heme oxygenase-1 (HO-1)reverse hypoxic pulmonary hypertension in HO-1 null mice

Authorship 337069
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linked information resource: Binding of Escherichia coli RNA polymerase to a specific site located near the 3'-end of the avaian sarcoma virus genome.

Authorship 3214
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author rank in publication: 2
linked author: Mitsialis, S. Alex
linked information resource: Studies on the developmentally regulated expression and amplification of insect chorion genes.

Authorship 556086
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linked information resource: Studies on the structure and organization of avian sarcoma proviruses in the rat XC cell line.

Authorship 571974
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author rank in publication: 8
linked author: Mitsialis, S. Alex
linked information resource: Targeted expression of heme oxygenase-1 prevents the pulmonary inflammatory and vascular responses to hypoxia.

Authorship 791291
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author rank in publication: 6
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linked information resource: The Sugen 5416/hypoxia mouse model of pulmonary hypertension revisited: long-term follow-up.

The Sugen 5416/hypoxia mouse model of pulmonary hypertension revisited: long-term follow-up.
PubMed Identifier: 25610598
author list: Vitali SH, Hansmann G, Rose C, Fernandez-Gonzalez A, Scheid A, Mitsialis SA, Kourembanas S
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Authorship 303304
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linked author: Mitsialis, S. Alex
linked information resource: Mesenchymal stromal cells expressing heme oxygenase-1 reverse pulmonary hypertension.

Authorship 335650
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linked author: Mitsialis, S. Alex
linked information resource: Carbon monoxide controls the proliferation of hypoxic vascular smooth muscle cells.

Authorship 472626
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linked author: Mitsialis, S. Alex
linked information resource: Effect of heme oxygenase-1 overexpression in two models of lung inflammation.

Authorship 481539
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linked author: Mitsialis, S. Alex
linked information resource: Mechanisms of heme oxygenase-1-mediated cardiac and pulmonary vascular protection in chronic hypoxia: roles of carbon monoxide and bilirubin.

Authorship 371885
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author rank in publication: 3
linked author: Mitsialis, S. Alex
linked information resource: Retinoic acid induces changes in the pattern of airway branching and alters epithelial cell differentiation in the developing lung in vitro.

Authorship 843048
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author rank in publication: 9
linked author: Mitsialis, S. Alex
linked information resource: https://connects.catalyst.harvard.edu/Profiles/profile/62065677

https://connects.catalyst.harvard.edu/Profiles/profile/62065677
PubMed Identifier: 26378259
author list: Cruz FF, Borg ZD, Goodwin M, Sokocevic D, Wagner DE, Coffey A, Antunes M, Robinson KL, Mitsialis SA, Kourembanas S, Thane K, Hoffman AM, McKenna DH, Rocco PR, Weiss DJ
published in: Stem cells translational medicine
information resource reference: Systemic Administration of Human Bone Marrow-Derived Mesenchymal Stromal Cell Extracellular Vesicles Ameliorates Aspergillus Hyphal Extract-Induced Allergic Airway Inflammation in Immunocompetent Mice. Stem Cells Transl Med. 2015 Nov; 4(11):1302-16.
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Authorship 610067
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linked information resource: Exacerbation of hypoxia-induced pulmonary hypertension and vascular remodeling in COX-2 deficient mice

Authorship 614868
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linked author: Mitsialis, S. Alex
linked information resource: Developmental control and evolution in the chorion gene families of insects

Authorship 875552
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author rank in publication: 1
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linked information resource: Stem cell-based therapies for the newborn lung and brain: Possibilities and challenges.

Stem cell-based therapies for the newborn lung and brain: Possibilities and challenges.
PubMed Identifier: 26778234
author list: Mitsialis SA, Kourembanas S
published in: Seminars in perinatology
information resource reference: Stem cell-based therapies for the newborn lung and brain: Possibilities and challenges. Semin Perinatol. 2016 Apr; 40(3):138-51.
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type: Document
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Authorship 496832
type: Authorship
author rank in publication: 2
linked author: Mitsialis, S. Alex
linked information resource: Hypoxia extends the life span of vascular smooth muscle cells through telomerase activation.

Authorship 587995
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linked author: Mitsialis, S. Alex
linked information resource: Hypoxic responses of vascular cells

Authorship 8904
type: Authorship
author rank in publication: 6
linked author: Mitsialis, S. Alex
linked information resource: Structural characterization and specificity of expression of E2F-5: a new member of the E2F family of transcription factors.

Assistant Professor
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Associate Professor
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Full Professor
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Authorship 620367
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linked author: Mitsialis, S. Alex
linked information resource: Transgenic mice overexpressing Heme Oxygenase - 1 (HO-1) in the lung are protected from development of hypoxia-induced pulmonary hypertension: Evidence of anti inflammatory effects of HO-1

Authorship 623606
type: Authorship
linked author: Mitsialis, S. Alex
linked information resource: Targeted expression of heme oxygenase-1 and pulmonary responses to hypoxia

Authorship 626742
type: Authorship
linked author: Mitsialis, S. Alex
linked information resource: Herbimycin and geldanamycin inhibit the hypoxic induction of the vascular endothelial growth factor (VEGF) in pulmonary artery endothelial cells

Authorship 509551
type: Authorship
author rank in publication: 2
linked author: Mitsialis, S. Alex
linked information resource: Cloning of avian tumor virus DNA fragments in plasmid pBR322: evidence for efficient transcription in E. coli from a virus-coded promoter.

Authorship 560571
type: Authorship
author rank in publication: 2
linked author: Mitsialis, S. Alex
linked information resource: Divergent cardiopulmonary actions of heme oxygenase enzymatic products in chronic hypoxia.

Authorship 507334
type: Authorship
author rank in publication: 4
linked author: Mitsialis, S. Alex
linked information resource: Ultraspiracle, a Drosophila retinoic X receptor alpha homologue, can mobilize the human thyroid hormone receptor to transactivate a human promoter.

Authorship 581052
type: Authorship
linked author: Mitsialis, S. Alex
linked information resource: Mechanisms of HO-1 cytopro-tection in hypoxic pulmonary hypertension

Authorship 582504
type: Authorship
linked author: Mitsialis, S. Alex
linked information resource: Extracellular acidosis induces Heme Oxygenase - 1 (HO-1) gene expression in vascular smooth muscle cells

Authorship 51549
type: Authorship
author rank in publication: 6
linked author: Mitsialis, S. Alex
linked information resource: Bone marrow stromal cells attenuate lung injury in a murine model of neonatal chronic lung disease.

Authorship 590740
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linked author: Mitsialis, S. Alex
linked information resource: Evolution of Structural Genes and Regulatory Elements for the Insect Chorion. In: () 1987; Vol. 8, pp

Authorship 611760
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linked author: Mitsialis, S. Alex
linked information resource: Heme Oxygenase-1 overexpression decreases alveolar remodeling and iron deposition in developmental lung injury

Authorship 609660
type: Authorship
linked author: Mitsialis, S. Alex
linked information resource: Bone-marrow derived mesenchymal stem cells expressing human HO-1 reverse hypoxic pulmonary hypertension in HO-1 null mice

DNA binding and heteromerization of the Drosophila transcription factor chorion factor 1/ultraspiracle.
PubMed Identifier: 1280827
author list: Christianson AM, King DL, Hatzivassiliou E, Casas JE, Hallenbeck PL, Nikodem VM, Mitsialis SA, Kafatos FC
published in: Proceedings of the National Academy of Sciences of the United States of America
information resource reference: DNA binding and heteromerization of the Drosophila transcription factor chorion factor 1/ultraspiracle. Proc Natl Acad Sci U S A. 1992 Dec 01; 89(23):11503-7.
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Retinoic acid alters the expression of pattern-related genes in the developing rat lung.
PubMed Identifier: 8875075
author list: Cardoso WV, Mitsialis SA, Brody JS, Williams MC
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information resource reference: Retinoic acid alters the expression of pattern-related genes in the developing rat lung. Dev Dyn. 1996 Sep; 207(1):47-59.
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Carbon monoxide controls the proliferation of hypoxic vascular smooth muscle cells.
PubMed Identifier: 9407056
author list: Morita T, Mitsialis SA, Koike H, Liu Y, Kourembanas S
published in: The Journal of biological chemistry
information resource reference: Carbon monoxide controls the proliferation of hypoxic vascular smooth muscle cells. J Biol Chem. 1997 Dec 26; 272(52):32804-9.
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300 Longwood Ave
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postal code: 02115
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Targeted expression of heme oxygenase-1 prevents the pulmonary inflammatory and vascular responses to hypoxia.
PubMed Identifier: 11447290
author list: Minamino T, Christou H, Hsieh CM, Liu Y, Dhawan V, Abraham NG, Perrella MA, Mitsialis SA, Kourembanas S
published in: Proceedings of the National Academy of Sciences of the United States of America
information resource reference: Targeted expression of heme oxygenase-1 prevents the pulmonary inflammatory and vascular responses to hypoxia. Proc Natl Acad Sci U S A. 2001 Jul 17; 98(15):8798-803.
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Exosomes mediate the cytoprotective action of mesenchymal stromal cells on hypoxia-induced pulmonary hypertension.
PubMed Identifier: 23114789
author list: Lee C, Mitsialis SA, Aslam M, Vitali SH, Vergadi E, Konstantinou G, Sdrimas K, Fernandez-Gonzalez A, Kourembanas S
published in: Circulation
information resource reference: Exosomes mediate the cytoprotective action of mesenchymal stromal cells on hypoxia-induced pulmonary hypertension. Circulation. 2012 Nov 27; 126(22):2601-11.
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Evolution of Structural Genes and Regulatory Elements for the Insect Chorion. In: () 1987; Vol. 8, pp
author list: Kafatos, F.C., S.A. Mitsialis, H.T. Nguyen, N. Spoerel, S.G. Tsitilou and G.D. Mazur.
published in: Development as an Evolutionary Process, R. Raff and E.C. Raff, eds.
information resource reference: Evolution of Structural Genes and Regulatory Elements for the Insect Chorion. In: () 1987; Vol. 8, pp. Development as an Evolutionary Process, R. Raff and E.C. Raff, eds. 1987; 161-178.
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Absence of cyclooxygenase-2 exacerbates hypoxia-induced pulmonary hypertension and enhances contractility of vascular smooth muscle cells.
PubMed Identifier: 18391113
author list: Fredenburgh LE, Liang OD, Macias AA, Polte TR, Liu X, Riascos DF, Chung SW, Schissel SL, Ingber DE, Mitsialis SA, Kourembanas S, Perrella MA
published in: Circulation
information resource reference: Absence of cyclooxygenase-2 exacerbates hypoxia-induced pulmonary hypertension and enhances contractility of vascular smooth muscle cells. Circulation. 2008 Apr 22; 117(16):2114-22.
journal title abbreviation: Circulation
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type: Academic Article
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Hypoxic responses of vascular cells
author list: Kourembanas S, Morita, T, Christou, H., Liu, Y., Koike, H., Brodsky, D., Arthur, V. and S. A. Mitsialis.
published in: Chest
information resource reference: Hypoxic responses of vascular cells. Chest. 1998; 25S-28S.
publication date: 1998-01-01T00:00:00
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type: Academic Article
type: Article
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The role of heme oxygenase-1 in pulmonary disease.
PubMed Identifier: 16980551
author list: Fredenburgh LE, Perrella MA, Mitsialis SA
published in: American journal of respiratory cell and molecular biology
information resource reference: The role of heme oxygenase-1 in pulmonary disease. Am J Respir Cell Mol Biol. 2007 Feb; 36(2):158-65.
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publication date: 2006-09-15T00:00:00
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type: Academic Article
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Bone marrow stromal cells attenuate lung injury in a murine model of neonatal chronic lung disease.
PubMed Identifier: 19713447
author list: Aslam M, Baveja R, Liang OD, Fernandez-Gonzalez A, Lee C, Mitsialis SA, Kourembanas S
published in: American journal of respiratory and critical care medicine
information resource reference: Bone marrow stromal cells attenuate lung injury in a murine model of neonatal chronic lung disease. Am J Respir Crit Care Med. 2009 Dec 01; 180(11):1122-30.
journal title abbreviation: Am J Respir Crit Care Med
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type: Academic Article
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Regulation of renal rK1-kallikrein in spontaneously hypertensive rats.
PubMed Identifier: 7686678
author list: Goud HD, Oza NB, Mitsialis SA, Levinsky NG
published in: Renal physiology and biochemistry
information resource reference: Regulation of renal rK1-kallikrein in spontaneously hypertensive rats. Ren Physiol Biochem. 1993 May-Jun; 16(3):125-30.
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type: Academic Article
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Structural characterization and specificity of expression of E2F-5: a new member of the E2F family of transcription factors.
PubMed Identifier: 8589754
author list: Itoh A, Levinson SF, Morita T, Kourembanas S, Brody JS, Mitsialis SA
published in: Cellular & molecular biology research
information resource reference: Structural characterization and specificity of expression of E2F-5: a new member of the E2F family of transcription factors. Cell Mol Biol Res. 1995; 41(3):147-54.
journal title abbreviation: Cell Mol Biol Res
publication date: 1995-01-01T00:00:00
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type: Academic Article
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Heme Oxygenase-1 overexpression decreases alveolar remodeling and iron deposition in developmental lung injury
author list: Fernandez-Gonzalez A, Naghshineh S, Mitsialis SA, Kourembanas S.
information resource reference: Heme Oxygenase-1 overexpression decreases alveolar remodeling and iron deposition in developmental lung injury. 2005.
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type: Academic Article
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Extracellular acidosis induces Heme Oxygenase - 1 (HO-1) gene expression in vascular smooth muscle cells
author list: Christou H, Minamino T, Mitsialis SA and Kourembanas S
published in: Pediatric Research
information resource reference: Extracellular acidosis induces Heme Oxygenase - 1 (HO-1) gene expression in vascular smooth muscle cells. Pediatric Research. 2000; 47(4):A386.
publication date: 2000-01-01T00:00:00
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Authorship 1006737
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linked information resource: Therapeutic Applications of Extracellular Vesicles: Perspectives from Newborn Medicine.

Authorship 1006252
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linked author: Mitsialis, S. Alex
linked information resource: Mesenchymal Stromal Cell Exosomes Ameliorate Experimental Bronchopulmonary Dysplasia and Restore Lung Function through Macrophage Immunomodulation.

Therapeutic Applications of Extracellular Vesicles: Perspectives from Newborn Medicine.
PubMed Identifier: 28828676
author list: Willis GR, Kourembanas S, Mitsialis SA
published in: Methods in molecular biology (Clifton, N.J.)
information resource reference: Therapeutic Applications of Extracellular Vesicles: Perspectives from Newborn Medicine. Methods Mol Biol. 2017; 1660:409-432.
journal title abbreviation: Methods Mol Biol
publication date: 2017-01-01T00:00:00
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type: Academic Article
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Mesenchymal Stromal Cell Exosomes Ameliorate Experimental Bronchopulmonary Dysplasia and Restore Lung Function through Macrophage Immunomodulation.
PubMed Identifier: 28853608
author list: Willis GR, Fernandez-Gonzalez A, Anastas J, Vitali SH, Liu X, Ericsson M, Kwong A, Mitsialis SA, Kourembanas S
published in: American journal of respiratory and critical care medicine
information resource reference: Mesenchymal Stromal Cell Exosomes Ameliorate Experimental Bronchopulmonary Dysplasia and Restore Lung Function through Macrophage Immunomodulation. Am J Respir Crit Care Med. 2018 01 01; 197(1):104-116.
journal title abbreviation: Am J Respir Crit Care Med
publication date: 2018-01-01T00:00:00
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type: Academic Article
type: Article
type: Document
type: Information Resource

Modification of avian sarcoma proviral DNA sequences in nonpermissive XC cells but not in permissive chicken cells.
PubMed Identifier: 6246282
author list: Guntaka RV, Rao PY, Mitsialis SA, Katz R
published in: Journal of virology
information resource reference: Modification of avian sarcoma proviral DNA sequences in nonpermissive XC cells but not in permissive chicken cells. J Virol. 1980 May; 34(2):569-72.
journal title abbreviation: J Virol
publication date: 1980-05-01T00:00:00
year: 1980
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1016137
type: Authorship
author rank in publication: 2
linked author: Mitsialis, S. Alex
linked information resource: "Good things come in small packages": application of exosome-based therapeutics in neonatal lung injury.

"Good things come in small packages": application of exosome-based therapeutics in neonatal lung injury.
PubMed Identifier: 28985201
author list: Willis GR, Mitsialis SA, Kourembanas S
published in: Pediatric research
information resource reference: "Good things come in small packages": application of exosome-based therapeutics in neonatal lung injury. Pediatr Res. 2018 01; 83(1-2):298-307.
journal title abbreviation: Pediatr Res
publication date: 2017-11-22T00:00:00
year: 2017
type: Academic Article
type: Article
type: Document
type: Information Resource

Localization of active promoters for eucaryotic RNA polymerase II in the long terminal repeat of avian sarcoma virus DNA.
PubMed Identifier: 6306447
author list: Mitsialis SA, Manley JL, Guntaka RV
published in: Molecular and cellular biology
information resource reference: Localization of active promoters for eucaryotic RNA polymerase II in the long terminal repeat of avian sarcoma virus DNA. Mol Cell Biol. 1983 May; 3(5):811-8.
journal title abbreviation: Mol Cell Biol
publication date: 1983-05-01T00:00:00
year: 1983
type: Academic Article
type: Article
type: Document
type: Information Resource

Retinoic acid induces changes in the pattern of airway branching and alters epithelial cell differentiation in the developing lung in vitro.
PubMed Identifier: 7742011
author list: Cardoso WV, Williams MC, Mitsialis SA, Joyce-Brady M, Rishi AK, Brody JS
published in: American journal of respiratory cell and molecular biology
information resource reference: Retinoic acid induces changes in the pattern of airway branching and alters epithelial cell differentiation in the developing lung in vitro. Am J Respir Cell Mol Biol. 1995 May; 12(5):464-76.
journal title abbreviation: Am J Respir Cell Mol Biol
publication date: 1995-05-01T00:00:00
year: 1995
type: Academic Article
type: Article
type: Document
type: Information Resource

Hypoxia induces macrophage inflammatory protein-2 (MIP-2) gene expression in murine macrophages via NF-kappaB: the prominent role of p42/ p44 and PI3 kinase pathways.
PubMed Identifier: 15132979
author list: Zampetaki A, Mitsialis SA, Pfeilschifter J, Kourembanas S
published in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology
information resource reference: Hypoxia induces macrophage inflammatory protein-2 (MIP-2) gene expression in murine macrophages via NF-kappaB: the prominent role of p42/ p44 and PI3 kinase pathways. FASEB J. 2004 Jul; 18(10):1090-2.
journal title abbreviation: FASEB J
publication date: 2004-05-07T00:00:00
year: 2004
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1022060
type: Authorship
author rank in publication: 3
linked author: Mitsialis, S. Alex
linked information resource: Toward Exosome-Based Therapeutics: Isolation, Heterogeneity, and Fit-for-Purpose Potency.

Toward Exosome-Based Therapeutics: Isolation, Heterogeneity, and Fit-for-Purpose Potency.
PubMed Identifier: 29062835
author list: Willis GR, Kourembanas S, Mitsialis SA
published in: Frontiers in cardiovascular medicine
information resource reference: Toward Exosome-Based Therapeutics: Isolation, Heterogeneity, and Fit-for-Purpose Potency. Front Cardiovasc Med. 2017; 4:63.
journal title abbreviation: Front Cardiovasc Med
publication date: 2017-10-09T00:00:00
year: 2017
type: Academic Article
type: Article
type: Document
type: Information Resource

Mechanisms of HO-1 cytopro-tection in hypoxic pulmonary hypertension
author list: Vitali, S., Mitsialis, S. A., Christou, H., Kourembanas, S.
published in: Pediatric Research
information resource reference: Mechanisms of HO-1 cytopro-tection in hypoxic pulmonary hypertension. Pediatric Research. 2004; 55(4):A2638.
publication date: 2004-01-01T00:00:00
year: 2004
type: Academic Article
type: Article
type: Document
type: Information Resource

Hypoxia extends the life span of vascular smooth muscle cells through telomerase activation.
PubMed Identifier: 11313459
author list: Minamino T, Mitsialis SA, Kourembanas S
published in: Molecular and cellular biology
information resource reference: Hypoxia extends the life span of vascular smooth muscle cells through telomerase activation. Mol Cell Biol. 2001 May; 21(10):3336-42.
journal title abbreviation: Mol Cell Biol
publication date: 2001-05-01T00:00:00
year: 2001
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1028159
type: Authorship
author rank in publication: 1
linked author: Mitsialis, S. Alex
linked information resource: Reply to Muraca et al.: Exosome Treatment of Bronchopulmonary Dysplasia: How Pure Should Your Exosome Preparation Be?

Reply to Muraca et al.: Exosome Treatment of Bronchopulmonary Dysplasia: How Pure Should Your Exosome Preparation Be?
PubMed Identifier: 29160730
author list: Mitsialis SA, Willis GR, Fernandez-Gonzalez A, Kourembanas S
published in: American journal of respiratory and critical care medicine
information resource reference: Reply to Muraca et al.: Exosome Treatment of Bronchopulmonary Dysplasia: How Pure Should Your Exosome Preparation Be? Am J Respir Crit Care Med. 2018 04 01; 197(7):970.
journal title abbreviation: Am J Respir Crit Care Med
publication date: 2018-04-01T00:00:00
year: 2018
type: Academic Article
type: Article
type: Document
type: Information Resource

Isolation and characterization of cDNA clones encoding human liver glutamate dehydrogenase: evidence for a small gene family.
PubMed Identifier: 3368458
author list: Mavrothalassitis G, Tzimagiorgis G, Mitsialis A, Zannis V, Plaitakis A, Papamatheakis J, Moschonas N
published in: Proceedings of the National Academy of Sciences of the United States of America
information resource reference: Isolation and characterization of cDNA clones encoding human liver glutamate dehydrogenase: evidence for a small gene family. Proc Natl Acad Sci U S A. 1988 May; 85(10):3494-8.
journal title abbreviation: Proc Natl Acad Sci U S A
publication date: 1988-05-01T00:00:00
year: 1988
type: Academic Article
type: Article
type: Document
type: Information Resource

Improved pulmonary vascular reactivity and decreased hypertrophic remodeling during nonhypercapnic acidosis in experimental pulmonary hypertension.
PubMed Identifier: 22287610
author list: Christou H, Reslan OM, Mam V, Tanbe AF, Vitali SH, Touma M, Arons E, Mitsialis SA, Kourembanas S, Khalil RA
published in: American journal of physiology. Lung cellular and molecular physiology
information resource reference: Improved pulmonary vascular reactivity and decreased hypertrophic remodeling during nonhypercapnic acidosis in experimental pulmonary hypertension. Am J Physiol Lung Cell Mol Physiol. 2012 May 01; 302(9):L875-90.
journal title abbreviation: Am J Physiol Lung Cell Mol Physiol
publication date: 2012-01-27T00:00:00
year: 2012
type: Academic Article
type: Article
type: Document
type: Information Resource

Developmental control and evolution in the chorion gene families of insects
author list: Kafatos, F.C., N. Spoerel, S.A. Mitsialis, H.T. Nguyen, C. Romano, J.R. Lingappa, B.D. Mariani, G.C. Rodakis, R. Lecanidou and S.G. Tsitilou.
published in: Advances in Genetics, J.G. Scandalios, ed.
information resource reference: Developmental control and evolution in the chorion gene families of insects. Advances in Genetics, J.G. Scandalios, ed. 1987; 223-242.
publication date: 1987-01-01T00:00:00
year: 1987
type: Academic Article
type: Article
type: Document
type: Information Resource

Heme Oxygenase and pulmonary responses to hypoxia
author list: Kourembanas S, Minamino T, Christou H, Hsieh C-M, Liu Y, Dhawan V, Lynch L, Abra-ham NG, Perella MA and Mitsialis SA.
published in: Acta Hematologica
information resource reference: Heme Oxygenase and pulmonary responses to hypoxia. Acta Hematologica. 2000; (103(1)):A276.
publication date: 2000-01-01T00:00:00
year: 2000
type: Academic Article
type: Article
type: Document
type: Information Resource

Bone-marrow derived mesenchymal stem cells expressing human HO-1 reverse hypoxic pulmonary hypertension in HO-1 null mice
author list: Liang O, Mitsialis SA, Kourembanas S
information resource reference: Bone-marrow derived mesenchymal stem cells expressing human HO-1 reverse hypoxic pulmonary hypertension in HO-1 null mice . 2005.
publication date: 2005-01-01T00:00:00
year: 2005
type: Academic Article
type: Article
type: Document
type: Information Resource

Transgenic regulation of moth chorion gene promoters in Drosophila: tissue, temporal, and quantitative control of four bidirectional promoters.
PubMed Identifier: 2559211
author list: Mitsialis SA, Veletza S, Kafatos FC
published in: Journal of molecular evolution
information resource reference: Transgenic regulation of moth chorion gene promoters in Drosophila: tissue, temporal, and quantitative control of four bidirectional promoters. J Mol Evol. 1989 Dec; 29(6):486-95.
journal title abbreviation: J Mol Evol
publication date: 1989-12-01T00:00:00
year: 1989
type: Academic Article
type: Article
type: Document
type: Information Resource

Transgenic mice overexpressing Heme Oxygenase - 1 (HO-1) in the lung are protected from development of hypoxia-induced pulmonary hypertension: Evidence of anti inflammatory effects of HO-1
author list: Christou H, Minamino T, Hsie C-M, Liu Y, Lynch L, Mitsialis SA, Perella MA, and Kourembanas S
published in: Pediatric Research
information resource reference: Transgenic mice overexpressing Heme Oxygenase - 1 (HO-1) in the lung are protected from development of hypoxia-induced pulmonary hypertension: Evidence of anti inflammatory effects of HO-1. Pediatric Research. 2000; 47(4):A385.
publication date: 2000-01-01T00:00:00
year: 2000
type: Academic Article
type: Article
type: Document
type: Information Resource

Early macrophage recruitment and alternative activation are critical for the later development of hypoxia-induced pulmonary hypertension.
PubMed Identifier: 21518986
author list: Vergadi E, Chang MS, Lee C, Liang OD, Liu X, Fernandez-Gonzalez A, Mitsialis SA, Kourembanas S
published in: Circulation
information resource reference: Early macrophage recruitment and alternative activation are critical for the later development of hypoxia-induced pulmonary hypertension. Circulation. 2011 May 10; 123(18):1986-95.
journal title abbreviation: Circulation
publication date: 2011-04-25T00:00:00
year: 2011
type: Academic Article
type: Article
type: Document
type: Information Resource

Mesenchymal stem cell-mediated reversal of bronchopulmonary dysplasia and associated pulmonary hypertension.
PubMed Identifier: 22837858
author list: Hansmann G, Fernandez-Gonzalez A, Aslam M, Vitali SH, Martin T, Mitsialis SA, Kourembanas S
published in: Pulmonary circulation
information resource reference: Mesenchymal stem cell-mediated reversal of bronchopulmonary dysplasia and associated pulmonary hypertension. Pulm Circ. 2012 Apr-Jun; 2(2):170-81.
journal title abbreviation: Pulm Circ
publication date: 2012-04-01T00:00:00
year: 2012
type: Academic Article
type: Article
type: Document
type: Information Resource

Exacerbation of hypoxia-induced pulmonary hypertension and vascular remodeling in COX-2 deficient mice
author list: Fredenburgh LE, Liang OD, Macias AA, Mitsialis SA, Kourembanas S , Perrella MA.
published in: American Thoracic Society International Conference Proceedings
information resource reference: Exacerbation of hypoxia-induced pulmonary hypertension and vascular remodeling in COX-2 deficient mice. American Thoracic Society International Conference Proceedings. 2006; (3):A278.
publication date: 2006-01-01T00:00:00
year: 2006
type: Academic Article
type: Article
type: Document
type: Information Resource

Ultraspiracle, a Drosophila retinoic X receptor alpha homologue, can mobilize the human thyroid hormone receptor to transactivate a human promoter.
PubMed Identifier: 9230055
author list: Hatzivassiliou E, Cardot P, Zannis VI, Mitsialis SA
published in: Biochemistry
information resource reference: Ultraspiracle, a Drosophila retinoic X receptor alpha homologue, can mobilize the human thyroid hormone receptor to transactivate a human promoter. Biochemistry. 1997 Jul 29; 36(30):9221-31.
journal title abbreviation: Biochemistry
publication date: 1997-07-29T00:00:00
year: 1997
type: Academic Article
type: Article
type: Document
type: Information Resource