Wild Edible Plants: Promoting Dietary Diversity in Poor Communities of Lebanon
Wild Edible Plants: Promoting Dietary Diversity in Poor Communities of Lebanon. 2007.
Fahed AC, El-Hage-Sleiman AK, Farhat TI, Nemer GM
Diet, genetics, and disease: a focus on the middle East and north Africa region. J Nutr Metab. 2012; 2012:109037.
Diet, genetics, and disease: a focus on the middle East and north Africa region.
Fahed AC, Safa RM, Haddad FF, Bitar FF, Andary RR, Arabi MT, Azar ST, Nemer G
Homozygous familial hypercholesterolemia in Lebanon: a genotype/phenotype correlation. Mol Genet Metab. 2011 Feb; 102(2):181-8.
Homozygous familial hypercholesterolemia in Lebanon: a genotype/phenotype correlation.
Shibbani K, Fahed AC, Al-Shaar L, Arabi M, Nemer G, Bitar F, Majdalani M
Primary carnitine deficiency: novel mutations and insights into the cardiac phenotype. Clin Genet. 2014 Feb; 85(2):127-37.
Primary carnitine deficiency: novel mutations and insights into the cardiac phenotype.
Krishnamurthy Y, Stefanescu Schmidt AC, Bittner DO, Scholtz JE, Bui A, Reddy R, Youniss MA, Donohoe K, Flannery LD, Fahed AC, Ghoshhajra BB, DeFaria Yeh D, Bhatt AB
Subclinical Burden of Coronary Artery Calcium in Patients With Coarctation of the Aorta. Am J Cardiol. 2019 01 15; 123(2):323-328.
Subclinical Burden of Coronary Artery Calcium in Patients With Coarctation of the Aorta.
Hariri H, Kurban M, Al-Haddad C, Fahed AC, Poladian S, Khalil A, Abbas O, Arabi M, Bitar F, Nemer G
Degenerated hair follicle cells and partial loss of sebaceous and eccrine glands in a familial case of axenfeld-rieger syndrome: An emerging role for the FOXC1/NFATC1 genetic axis. J Dermatol Sci. 2018 Dec; 92(3):237-244.
Degenerated hair follicle cells and partial loss of sebaceous and eccrine glands in a familial case of axenfeld-rieger syndrome: An emerging role for the FOXC1/NFATC1 genetic axis.
Familial hypercholesterolemia: the lipids or the genes? Nutr Metab (Lond). 2011 Apr 22; 8(1):23.
Familial hypercholesterolemia: the lipids or the genes?
Translational Medicine in the Era of Big Data and Machine Learning. Circ Res. 2018 11 09; 123(11):1202-1204.
Translational Medicine in the Era of Big Data and Machine Learning.
Steven E. Seltzer, MD, Professor of Radiology
Allan and Gill Gray Professor of Medicine in the Field of Cardiology
Patel AP, Wang M, Fahed AC, Mason-Suares H, Brockman D, Pelletier R, Amr S, Machini K, Hawley M, Witkowski L, Koch C, Philippakis A, Cassa CA, Ellinor PT, Kathiresan S, Ng K, Lebo M, Khera AV
Association of Rare Pathogenic DNA Variants for Familial Hypercholesterolemia, Hereditary Breast and Ovarian Cancer Syndrome, and Lynch Syndrome With Disease Risk in Adults According to Family History. JAMA Netw Open. 2020 04 01; 3(4):e203959.
Association of Rare Pathogenic DNA Variants for Familial Hypercholesterolemia, Hereditary Breast and Ovarian Cancer Syndrome, and Lynch Syndrome With Disease Risk in Adults According to Family History.
Fahed AC, Wang M, Homburger JR, Patel AP, Bick AG, Neben CL, Lai C, Brockman D, Philippakis A, Ellinor PT, Cassa CA, Lebo M, Ng K, Lander ES, Zhou AY, Kathiresan S, Khera AV
Polygenic background modifies penetrance of monogenic variants for tier 1 genomic conditions. Nat Commun. 2020 08 20; 11(1):3635.
Polygenic background modifies penetrance of monogenic variants for tier 1 genomic conditions.
Fahed AC, Nemer G, Bitar FF, Arnaout S, Abchee AB, Batrawi M, Khalil A, Abou Hassan OK, DePalma SR, McDonough B, Arabi MT, Ware JS, Seidman JG, Seidman CE
Circulation. Genomic and precision medicine
Founder Mutation in N Terminus of Cardiac Troponin I Causes Malignant Hypertrophic Cardiomyopathy. Circ Genom Precis Med. 2020 10; 13(5):444-452.
Founder Mutation in N Terminus of Cardiac Troponin I Causes Malignant Hypertrophic Cardiomyopathy.
Fahed AC, Aragam KG, Hindy G, Chen YI, Chaudhary K, Dobbyn A, Krumholz HM, Sheu WHH, Rich SS, Rotter JI, Chowdhury R, Cho J, Do R, Ellinor PT, Kathiresan S, Khera AV
Transethnic Transferability of a Genome-Wide Polygenic Score for Coronary Artery Disease. Circ Genom Precis Med. 2021 02; 14(1):e003092.
Transethnic Transferability of a Genome-Wide Polygenic Score for Coronary Artery Disease.
Plaque erosion and acute coronary syndromes: phenotype, molecular characteristics and future directions. Nat Rev Cardiol. 2021 10; 18(10):724-734.
Plaque erosion and acute coronary syndromes: phenotype, molecular characteristics and future directions.
Lormeau B, Fahed A, Marminc L, Miossec P, Valensi P, Attali JR
[The "short Achilles tendon" syndrome: a new entity of the diabetic foot]. Diabetes Metab. 1997 Nov; 23(5):443-7.
[The "short Achilles tendon" syndrome: a new entity of the diabetic foot].
Brockman DG, Petronio L, Dron JS, Kwon BC, Vosburg T, Nip L, Tang A, O'Reilly M, Lennon N, Wong B, Ng K, Huang KH, Fahed AC, Khera AV
Design and user experience testing of a polygenic score report: a qualitative study of prospective users. BMC Med Genomics. 2021 10 01; 14(1):238.
Design and user experience testing of a polygenic score report: a qualitative study of prospective users.
Fahed AC, Wang M, Patel AP, Ajufo E, Maamari DJ, Aragam KG, Brockman DG, Vosburg T, Ellinor PT, Ng K, Khera AV
Association of the Interaction Between Familial Hypercholesterolemia Variants and Adherence to a Healthy Lifestyle With Risk of Coronary Artery Disease. JAMA Netw Open. 2022 03 01; 5(3):e222687.
Association of the Interaction Between Familial Hypercholesterolemia Variants and Adherence to a Healthy Lifestyle With Risk of Coronary Artery Disease.
Maamari DJ, Jaffer FA, Khera AV, Fahed AC
CYP2C19 Genotyping in Anticoagulated Patients After Percutaneous Coronary Intervention: Should It Be Routine? Circulation. 2022 03 08; 145(10):721-723.
CYP2C19 Genotyping in Anticoagulated Patients After Percutaneous Coronary Intervention: Should It Be Routine?
The potential of polygenic scores to improve cost and efficiency of clinical trials. Nat Commun. 2022 05 25; 13(1):2922.
The potential of polygenic scores to improve cost and efficiency of clinical trials.
Maamari DJ, Brockman DG, Aragam K, Pelletier RC, Folkerts E, Neben CL, Okumura S, Hull LE, Philippakis AA, Natarajan P, Ellinor PT, Ng K, Zhou AY, Khera AV, Fahed AC
Clinical Implementation of Combined Monogenic and Polygenic Risk Disclosure for Coronary Artery Disease. JACC Adv. 2022 Aug; 1(3).
Clinical Implementation of Combined Monogenic and Polygenic Risk Disclosure for Coronary Artery Disease.
Hindy G, Tyrrell DJ, Vasbinder A, Wei C, Presswalla F, Wang H, Blakely P, Ozel AB, Graham S, Holton GH, Dowsett J, Fahed AC, Amadi KM, Erne GK, Tekmulla A, Ismail A, Launius C, Sotoodehnia N, Pankow JS, Thørner LW, Erikstrup C, Pedersen OB, Banasik K, Brunak S, Ullum H, Eugen-Olsen J, Ostrowski SR, Haas ME, Nielsen JB, Lotta LA, Engström G, Melander O, Orho-Melander M, Zhao L, Murthy VL, Pinsky DJ, Willer CJ, Heckbert SR, Reiser J, Goldstein DR, Desch KC, Hayek SS
Increased soluble urokinase plasminogen activator levels modulate monocyte function to promote atherosclerosis. J Clin Invest. 2022 12 15; 132(24).
Increased soluble urokinase plasminogen activator levels modulate monocyte function to promote atherosclerosis.
Jowell AR, Bhattacharya R, Marnell C, Wong M, Haidermota S, Trinder M, Fahed AC, Peloso GM, Honigberg MC, Natarajan P
European journal of preventive cardiology
Genetic and clinical factors underlying a self-reported family history of heart disease. Eur J Prev Cardiol. 2023 10 26; 30(15):1571-1579.
Genetic and clinical factors underlying a self-reported family history of heart disease.
Kartoun U, Fahed AC, Kany S, Singh P, Khurshid S, Patel AP, Batra P, Philippakis A, Khera AV, Lubitz SA, Ellinor PT, Anand V, Ng K
Exploring the link between Gilbert's syndrome and atherosclerotic cardiovascular disease: insights from a subpopulation-based analysis of over one million individuals. Eur Heart J Open. 2023 May; 3(3):oead059.
Exploring the link between Gilbert's syndrome and atherosclerotic cardiovascular disease: insights from a subpopulation-based analysis of over one million individuals.
Qamar I, Grewal S, Fahed AC, Weiner R, Tawakol A, Osborne MT
Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology
PET myocardial perfusion imaging of regadenoson-induced coronary vasospasm. J Nucl Cardiol. 2023 10; 30(5):2187-2190.
PET myocardial perfusion imaging of regadenoson-induced coronary vasospasm.
Patel AP, Wang M, Ruan Y, Koyama S, Clarke SL, Yang X, Tcheandjieu C, Agrawal S, Fahed AC, Ellinor PT, Tsao PS, Sun YV, Cho K, Wilson PWF, Assimes TL, van Heel DA, Butterworth AS, Aragam KG, Natarajan P, Khera AV
A multi-ancestry polygenic risk score improves risk prediction for coronary artery disease. Nat Med. 2023 07; 29(7):1793-1803.
A multi-ancestry polygenic risk score improves risk prediction for coronary artery disease.
Pragmatic Approach to Applying Polygenic Risk Scores to Diverse Populations. Curr Protoc. 2023 Nov; 3(11):e911.
Pragmatic Approach to Applying Polygenic Risk Scores to Diverse Populations.
Shim I, Kuwahara H, Chen N, Hashem MO, AlAbdi L, Abouelhoda M, Won HH, Natarajan P, Ellinor PT, Khera AV, Gao X, Alkuraya FS, Fahed AC
Clinical utility of polygenic scores for cardiometabolic disease in Arabs. Nat Commun. 2023 10 18; 14(1):6535.
Clinical utility of polygenic scores for cardiometabolic disease in Arabs.
Clinical applications of polygenic risk score for coronary artery disease through the life course. Atherosclerosis. 2023 12; 386:117356.
Clinical applications of polygenic risk score for coronary artery disease through the life course.
Urbut SM, Yeung MW, Khurshid S, Cho SMJ, Schuermans A, German J, Taraszka K, Fahed AC, Ellinor P, Trinquart L, Parmigiani G, Gusev A, Natarajan P
medRxiv : the preprint server for health sciences
MSGene: Derivation and validation of a multistate model for lifetime risk of coronary artery disease using genetic risk and the electronic health record. medRxiv. 2023 Nov 08.
MSGene: Derivation and validation of a multistate model for lifetime risk of coronary artery disease using genetic risk and the electronic health record.
Bhattacharya R, Chen N, Shim I, Kuwahara H, Gao X, Alkuraya FS, Fahed AC
Massive underrepresentation of Arabs in genomic studies of common disease. Genome Med. 2023 11 22; 15(1):99.
Massive underrepresentation of Arabs in genomic studies of common disease.
Urbut SM, Cho SMJ, Paruchuri K, Truong B, Haidermota S, Peloso G, Hornsby W, Philippakis A, Fahed AC, Natarajan P
Dynamic Importance of Genomic and Clinical Risk for Coronary Artery Disease Over the Life Course. medRxiv. 2023 Nov 04.
Dynamic Importance of Genomic and Clinical Risk for Coronary Artery Disease Over the Life Course.
Machine Learning in Invasive and Noninvasive Coronary Angiography. Curr Atheroscler Rep. 2023 12; 25(12):1025-1033.
Machine Learning in Invasive and Noninvasive Coronary Angiography.
PET myocardial perfusion imaging of regadenoson-induced coronary vasospasm. J Nucl Cardiol. 2023 Oct; 30(5):2187-2190.
The Role of Genetics in Advancing Cardiometabolic Drug Development. Curr Atheroscler Rep. 2024 05; 26(5):153-162.
The Role of Genetics in Advancing Cardiometabolic Drug Development.
Bou Ghannam A, Istambouli R, Hamam MS, Chalhoub JM, Fahed AC, Hamam RN
Ocular manifestations of severe familial hypercholesterolemia. Heliyon. 2024 May 15; 10(9):e30487.
Ocular manifestations of severe familial hypercholesterolemia.
Urbut SM, Yeung MW, Khurshid S, Cho SMJ, Schuermans A, German J, Taraszka K, Paruchuri K, Fahed AC, Ellinor PT, Trinquart L, Parmigiani G, Gusev A, Natarajan P
MSGene: a multistate model using genetic risk and the electronic health record applied to lifetime risk of coronary artery disease. Nat Commun. 2024 Jun 07; 15(1):4884.
MSGene: a multistate model using genetic risk and the electronic health record applied to lifetime risk of coronary artery disease.
Reeskamp LF, Shim I, Dron JS, Ibrahim S, Tromp TR, Fahed AC, Patel AP, Hutten BA, Stroes ESG, Hovingh GK, Khera AV
Polygenic Background Modifies Risk of Coronary Artery Disease Among Individuals With Heterozygous Familial Hypercholesterolemia. JACC Adv. 2023 Nov; 2(9):100662.
Polygenic Background Modifies Risk of Coronary Artery Disease Among Individuals With Heterozygous Familial Hypercholesterolemia.
Kim MS, Shim I, Fahed AC, Do R, Park WY, Natarajan P, Khera AV, Won HH
Association of genetic risk, lifestyle, and their interaction with obesity and obesity-related morbidities. Cell Metab. 2024 Jul 02; 36(7):1494-1503.e3.
Association of genetic risk, lifestyle, and their interaction with obesity and obesity-related morbidities.
Kany S, Rämö JT, Friedman SF, Weng LC, Roselli C, Kim MS, Fahed AC, Lubitz SA, Maddah M, Ellinor PT, Khurshid S
Integrating Clinical, Genetic, and Electrocardiogram-Based Artificial Intelligence to Estimate Risk of Incident Atrial Fibrillation. medRxiv. 2024 Aug 14.
Integrating Clinical, Genetic, and Electrocardiogram-Based Artificial Intelligence to Estimate Risk of Incident Atrial Fibrillation.
Nurmohamed NS, Shim I, Gaillard EL, Ibrahim S, Bom MJ, Earls JP, Min JK, Planken RN, Choi AD, Natarajan P, Stroes ESG, Knaapen P, Reeskamp LF, Fahed AC
Polygenic Risk Is Associated With Long-Term Coronary Plaque Progression and High-Risk Plaque. JACC Cardiovasc Imaging. 2024 Dec; 17(12):1445-1459.
Polygenic Risk Is Associated With Long-Term Coronary Plaque Progression and High-Risk Plaque.
Misra A, Truong B, Urbut SM, Sui Y, Fahed AC, Smoller JW, Patel AP, Natarajan P
Instability of high polygenic risk classification and mitigation by integrative scoring. medRxiv. 2024 Oct 28.
Instability of high polygenic risk classification and mitigation by integrative scoring.
Journal of the Society for Cardiovascular Angiography & Interventions
Does Mechanical Circulatory Support-Assisted Percutaneous Coronary Intervention Improve Left Ventricular Function? J Soc Cardiovasc Angiogr Interv. 2022 Sep-Oct; 1(5):100387.
Does Mechanical Circulatory Support-Assisted Percutaneous Coronary Intervention Improve Left Ventricular Function?
Pregnancy in a woman with homozygous familial hypercholesterolemia not on low-density lipoprotein apheresis. AJP Rep. 2012 Nov; 2(1):33-6.
Pregnancy in a woman with homozygous familial hypercholesterolemia not on low-density lipoprotein apheresis.
Park S, Kim S, Kim B, Kim DS, Kim J, Ahn Y, Kim H, Song M, Shim I, Jung SH, Cho C, Lim S, Hong S, Jo H, Fahed AC, Natarajan P, Ellinor PT, Torkamani A, Park WY, Yu TY, Myung W, Won HH
Multivariate genomic analysis of 5?million people elucidates the genetic architecture of shared components of the metabolic syndrome. Nat Genet. 2024 Nov; 56(11):2380-2391.
Multivariate genomic analysis of 5?million people elucidates the genetic architecture of shared components of the metabolic syndrome.
Supriami K, Urbut SM, Tello-Ayala JR, Unlu O, Friedman SF, Abou-Karam R, Koyama S, Uddin MM, Pomerantsev E, Lu MT, Honigberg MC, Aragam KG, Doshi-Velez F, Patel AP, Natarajan P, Ellinor PT, Fahed AC
Genomic Drivers of Coronary Artery Disease and Risk of Future Outcomes After Coronary Angiography. JAMA Netw Open. 2025 01 02; 8(1):e2455368.
Genomic Drivers of Coronary Artery Disease and Risk of Future Outcomes After Coronary Angiography.
Polygenic Risk Scores in Human Disease. Clin Chem. 2025 Jan 03; 71(1):69-76.
Urbut SM, Cho SMJ, Paruchuri K, Truong B, Haidermota S, Peloso GM, Hornsby WE, Philippakis A, Fahed AC, Natarajan P
Dynamic Importance of Genomic and Clinical Risk for Coronary Artery Disease Over the Life Course. Circ Genom Precis Med. 2025 Feb; 18(1):e004681.
Khan N, Shaar A, Kunji K, Khan A, Elshrif M, Bashir M, Ali MT, Al Haj Zen A, Kiryluk K, Nemer G, Fahed AC, Saad M
Journal of the American Heart Association
Genome-Wide Association Study for Resting Electrocardiogram in the Qatari Population Identifies 6 Novel Genes and Validates Novel Polygenic Risk Scores. J Am Heart Assoc. 2025 Mar 04; 14(5):e038341.
Genome-Wide Association Study for Resting Electrocardiogram in the Qatari Population Identifies 6 Novel Genes and Validates Novel Polygenic Risk Scores.
Instability of high polygenic risk classification and mitigation by integrative scoring. Nat Commun. 2025 Feb 12; 16(1):1584.
Fahed AC, Roberts AE, Mital S, Lakdawala NK
Heart failure in congenital heart disease: a confluence of acquired and congenital. Heart Fail Clin. 2014 Jan; 10(1):219-27.
Heart failure in congenital heart disease: a confluence of acquired and congenital.
Kim MS, Khurshid S, Kany S, Weng LC, Urbut S, Roselli C, Wijdeveld LFJM, Jurgens SJ, Rämö JT, Ellinor PT, Fahed AC
Machine Learning-Based Plasma Protein Risk Score Improves Atrial Fibrillation Prediction Over Clinical and Genomic Models. Circ Genom Precis Med. 2025 Aug; 18(4):e004943.
Machine Learning-Based Plasma Protein Risk Score Improves Atrial Fibrillation Prediction Over Clinical and Genomic Models.
Kany S, Friedman SF, Al-Alusi M, Khurshid S, Rämö JT, Pipilas D, Pirruccello JP, Reeder C, Philippakis AA, Ho JE, Maddah M, Ellinor PT, Fahed AC
Electrocardiogram-Based Artificial Intelligence to Identify Coronary Artery Disease. JACC Adv. 2025 Sep; 4(9):102041.
Electrocardiogram-Based Artificial Intelligence to Identify Coronary Artery Disease.
Cho SMJ, Levin M, Chen R, Samarakoon R, Judy R, Hartmann K, Postupaka D, Viscosi V, Farber-Eger E, Fahed AC, Honigberg MC, Patel CJ, Hornsby W, Wells QS, Damrauer SM, Do R, Natarajan P
Journal of the American College of Cardiology
AHA PREVENT Equations and Cardiovascular Disease Risk in Diverse Health Care Populations. J Am Coll Cardiol. 2025 Jul 22; 86(3):181-192.
AHA PREVENT Equations and Cardiovascular Disease Risk in Diverse Health Care Populations.
Genetic Causes of Syndromic and Non-Syndromic Congenital Heart Disease
"Mutations in Human Genetic Disease", edited by David N. Cooper and Jian-Min Chen. Genetic Causes of Syndromic and Non-Syndromic Congenital Heart Disease. 2012.
"Mutations in Human Genetic Disease", edited by David N. Cooper and Jian-Min Chen
Fahed AC, Habib RH, Nemer GM, Azar ST, Andary RR, Arabi MT, Moubarak EM, Bitar FF, Haddad FF
Low-density lipoprotein levels and not mutation status predict intima-media thickness in familial hypercholesterolemia. Ann Vasc Surg. 2014 Feb; 28(2):421-6.
Low-density lipoprotein levels and not mutation status predict intima-media thickness in familial hypercholesterolemia.
Zhang R, Kim MS, Yin W, Liao S, Zhu X, Yang X, Yu K, Sui Y, Roselli C, Khurshid S, Chen Q, A Y, Zhao H, Xu T, Huang X, Pu J, Liu Z, Natarajan P, Zhai G, Ellinor PT, Wang M, Fahed AC
Contributions of Common, Rare, and Somatic Genetic Variants to Incidence of Atrial Fibrillation. JAMA Cardiol. 2025 Dec 01; 10(12):1240-1248.
Contributions of Common, Rare, and Somatic Genetic Variants to Incidence of Atrial Fibrillation.
Supriami K, Faaborg-Andersen CC, Cho SMJ, Tello-Ayala JR, Abou-Karam R, Pomerantsev E, Viscosi V, Haidermota S, Hornsby W, Natarajan P, Ellinor PT, Honigberg MC, Fahed AC
Outcomes after coronary angiography in individuals with elevated lipoprotein(a). Eur J Prev Cardiol. 2025 Nov 13.
Outcomes after coronary angiography in individuals with elevated lipoprotein(a).
Cho SMJ, Ruan Y, Lee HH, Koyama S, Juraschek SP, Allen NB, Yang E, McEvoy JW, Secemsky EA, Honigberg MC, Fahed AC, Patel AP, Hornsby WE, Natarajan P
Blood Pressure Polygenic Score Predicts Long-Term Blood Pressure Control and Treatment-Resistant Hypertension. Hypertension. 2026 Mar; 83(3):e26399.
Blood Pressure Polygenic Score Predicts Long-Term Blood Pressure Control and Treatment-Resistant Hypertension.
Mashlah A, Marini S, Mills H, Yahya T, Radmanesh F, Chalif J, Zusman BE, Bernstock JD, Al Mansi MH, Grashow R, Abd-El-Barr MM, Zaidi HA, Lu Y, Salim A, Fahed AC, Manley GT, Halabi C, Digiorgio A, Zafonte R, Izzy S
Traumatic Spinal Cord Injury and Subsequent Risk of Developing Chronic Cardiovascular, Neurologic, Psychiatric, and Endocrine Disorders. JAMA Netw Open. 2025 Nov 03; 8(11):e2541157.
Traumatic Spinal Cord Injury and Subsequent Risk of Developing Chronic Cardiovascular, Neurologic, Psychiatric, and Endocrine Disorders.
Kim MS, Song M, Kim H, Park S, Shim I, Lim S, Kim B, Chen X, Sui Y, Jemma Cho SM, Koyama S, Yun JS, Natarajan P, Ellinor PT, Fahed AC, Won HH
Genomics reveals eleven obesity endotypes with distinct biological and phenotypic signatures. medRxiv. 2025 Jul 02.
Genomics reveals eleven obesity endotypes with distinct biological and phenotypic signatures.
Urbut SM, Chen Q, Sui Y, Misra A, Koyama S, Hornsby W, Peloso GM, Finer S, van Heel DA, Ito K, Alkuraya F, Fahed AC, Wang M, Natarajan P
Genetics of Cholesterol and Coronary Disease Risk across Six Global Ancestries. NEJM Evid. 2025 Nov; 4(11):EVIDoa2500105.
Genetics of Cholesterol and Coronary Disease Risk across Six Global Ancestries.
Koyama S, Wang Y, Paruchuri K, Uddin MM, Cho SMJ, Urbut SM, Sui Y, Fahed AC, Kamineni H, Haidermota S, Hornsby WE, Green RC, Daly MJ, Neale BM, Ellinor PT, Smoller JW, Slaugenhaupt SA, Lebo MS, Karlson EW, Martin AR, Natarajan P
Genetics and context for precision health in Greater Boston. Nat Commun. 2025 Nov 26; 16(1):11661.
Genetics and context for precision health in Greater Boston.
Abou-Karam R, Kim MS, Jemma Cho SM, Bitar F, Gady S, Cheng F, Thompson AG, Karlson EW, Natarajan P, Ellinor PT, Foldyna B, Ghebremichael MS, Atlas SJ, Ridker PM, Lu MT, Fahed AC
Polygenic Risk Based Detection and Treatment of Subclinical Coronary Atherosclerosis in the PROACT Clinical Trials. J Am Coll Cardiol. 2026 Feb 06.
Polygenic Risk Based Detection and Treatment of Subclinical Coronary Atherosclerosis in the PROACT Clinical Trials.
Fahed AC, McDonough B, Gouvion CM, Newell KL, Dure LS, Bebin M, Bick AG, Seidman JG, Harter DH, Seidman CE
UBQLN2 mutation causing heterogeneous X-linked dominant neurodegeneration. Ann Neurol. 2014 May; 75(5):793-798.
UBQLN2 mutation causing heterogeneous X-linked dominant neurodegeneration.
Chen X, Wang F, Zhao H, Hao J, A Y, Yang X, Xu T, Zhou Y, Chen Q, Zhang R, Yu K, Zaib K, Fahed AC, Zhai G, Wang M
Comprehensive benchmarking single and multi ancestry polygenic score methods with the PGS-hub platform. Nat Commun. 2026 Jan 25; 17(1).
Comprehensive benchmarking single and multi ancestry polygenic score methods with the PGS-hub platform.
Kim MS, Park S, Kim JH, Myung W, Song M, Do R, Nho K, Kim E, Hwang S, Yu Z, Natarajan P, Kim HJ, Son HJ, Park WY, Sui Y, Fahed AC, Ellinor PT, Ali M, Gong K, Cruchaga C, Yon DK, Seo J, Shin JY, Jo DG, Won HH
ACE inhibition increases Alzheimer's disease risk by promoting tau phosphorylation. medRxiv. 2025 Aug 12.
ACE inhibition increases Alzheimer's disease risk by promoting tau phosphorylation.
Galo J, Maksoud A, Shah S, Toleva O, Kobayashi Y, Fahed AC, Shlofmitz E, Sharma A, Buijs JOD, Spinelli J, Rapoza R, Bergmark B, Hashim H
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions
Predictors of Variability in Coronary Flow Reserve and Microvascular Resistance Measurement Using the Bolus Thermodilution Technique. Catheter Cardiovasc Interv. 2026 Jan; 107(1):153-161.
Predictors of Variability in Coronary Flow Reserve and Microvascular Resistance Measurement Using the Bolus Thermodilution Technique.
El Ghazawi A, Fahed AC, Fawaz N, Fakih Y, Alam S, Refaat M
American heart journal plus : cardiology research and practice
Unraveling the genetic blueprint of coronary artery disease: The role of polygenic risk scores in risk prediction. Am Heart J Plus. 2026 Feb; 62:100712.
Unraveling the genetic blueprint of coronary artery disease: The role of polygenic risk scores in risk prediction.
Bergmark BA, Shah S, Toleva O, Maksoud A, Kearney KE, Kobayashi Y, Fahed AC, Hashim H, Sharma A, Blair J, Chehab BM, Kanakadandi U, Jaffer FA, Jeremias A, Gross DA, Baljepally R, Ali ZA, Reddy G, Shlofmitz E, Moussa I, Zhang S, Murphy SA, Ahmed S, Spinelli J, Meinen J, Rapoza RJ, Sabatine MS
Multicenter Prospective Assessment of Coronary Microvascular Dysfunction: Primary Results of the FlowLab Study. JACC Adv. 2025 Nov; 4(11 Pt 1):102179.
Multicenter Prospective Assessment of Coronary Microvascular Dysfunction: Primary Results of the FlowLab Study.
Bedrouni W, Bedrouni M, Fahed AC, Anand SS, Bessissow A, Touyz R, Huynh T
Grant Funding for Immigrant Cardiovascular Health Research in the US and Canada. JAMA Netw Open. 2025 Dec 01; 8(12):e2546110.
Grant Funding for Immigrant Cardiovascular Health Research in the US and Canada.
Hariri H, Farhat T, Khalaf R, Fahed A, Al-Haddad C, Arabi M, Bitar F, Nemer G
P569A novel role for NFATC1 in patients with both congenital heart disease and glaucoma. Cardiovasc Res. 2014 Jul 15; 103 Suppl 1:S102.
P569A novel role for NFATC1 in patients with both congenital heart disease and glaucoma.
Kassab K, Hariri H, Fahed A, El-Rassi I, Bitar F, Nemer G
P329GATA5: a key player in congenital heart diseases. Cardiovasc Res. 2014 Jul 15; 103 Suppl 1:S59-60.
P329GATA5: a key player in congenital heart diseases.
Nazha B, Salloum RH, Fahed AC, Nabulsi M
Students' perceptions of peer-organized extra-curricular research course during medical school: a qualitative study. PLoS One. 2015; 10(3):e0119375.
Students' perceptions of peer-organized extra-curricular research course during medical school: a qualitative study.
Abou Hassan OK, Fahed AC, Batrawi M, Arabi M, Refaat MM, DePalma SR, Seidman JG, Seidman CE, Bitar FF, Nemer GM
NKX2-5 mutations in an inbred consanguineous population: genetic and phenotypic diversity. Sci Rep. 2015 Mar 06; 5:8848.
NKX2-5 mutations in an inbred consanguineous population: genetic and phenotypic diversity.
Gharibeh L, El-Rassy I, Soubra A, Safa R, Fahed A, Tanos R, Arabi M, Kambris Z, Bitar F, Nemer G
A novel nonsense mutation in NPHS1: is aortic stenosis associated with congenital nephropathy? J Genet. 2015 Jun; 94(2):309-12.
A novel nonsense mutation in NPHS1: is aortic stenosis associated with congenital nephropathy?
Fahed AC, Nemer G, Bitar FF, Arnaout S, Abchee AB, Ware J, Batrawi M, DePalma SR, McDonough B, Arabi MT, Seidman JG, Seidman CE
The R21C Mutation in Troponin I has a Founder Effect in South Lebanon and Causes Malignant Hypertrophic Cardiomyopathy
Journal of the American College of Cardiology. The R21C Mutation in Troponin I has a Founder Effect in South Lebanon and Causes Malignant Hypertrophic Cardiomyopathy. 2015; 65(10S).
Refaat MM, Fahed AC, Hassanieh S, Hotait M, Arabi M, Skouri H, Seidman JG, Seidman CE, Bitar FF, Nemer G
The Muscle-Bound Heart. Card Electrophysiol Clin. 2016 Mar; 8(1):223-31.
Kassab K, Hariri H, Gharibeh L, Fahed AC, Zein M, El-Rassy I, Nemer M, El-Rassi I, Bitar F, Nemer G
GATA5 mutation homozygosity linked to a double outlet right ventricle phenotype in a Lebanese patient. Mol Genet Genomic Med. 2016 Mar; 4(2):160-71.
GATA5 mutation homozygosity linked to a double outlet right ventricle phenotype in a Lebanese patient.
Fahed AC, Khalaf R, Salloum R, Andary RR, Safa R, El-Rassy I, Moubarak E, Azar ST, Bitar FF, Nemer G
Variable expressivity and co-occurrence of LDLR and LDLRAP1 mutations in familial hypercholesterolemia: failure of the dominant and recessive dichotomy. Mol Genet Genomic Med. 2016 May; 4(3):283-91.
Variable expressivity and co-occurrence of LDLR and LDLRAP1 mutations in familial hypercholesterolemia: failure of the dominant and recessive dichotomy.
Journal of the American Academy of Dermatology
Yellow plaques on the hands of a 10-year-old girl. J Am Acad Dermatol. 2017 Jun; 76(6):e193-e194.
Yellow plaques on the hands of a 10-year-old girl.
Fahed AC, Gelb BD, Seidman JG, Seidman CE
Genetics of congenital heart disease: the glass half empty. Circ Res. 2013 Feb 15; 112(4):707-20.
Genetics of congenital heart disease: the glass half empty.
Fahed AC, Bitar FF, Khalaf RI, Moubarak EM, Azar ST, Nemer GM
The Lebanese allele at the LDLR in normocholesterolemic people merits reconsideration of genotype phenotype correlations in familial hypercholesterolemia. Endocrine. 2012 Oct; 42(2):445-8.
The Lebanese allele at the LDLR in normocholesterolemic people merits reconsideration of genotype phenotype correlations in familial hypercholesterolemia.
Fahed AC, Nonaka D, Kanofsky JA, Huang WC
Cystic mucinous tumors of the urachus: carcinoma in situ or adenoma of unknown malignant potential? Can J Urol. 2012 Jun; 19(3):6310-3.
Cystic mucinous tumors of the urachus: carcinoma in situ or adenoma of unknown malignant potential?
Connecting the Lines between Hypogonadism and Atherosclerosis. Int J Endocrinol. 2012; 2012:793953.
Connecting the Lines between Hypogonadism and Atherosclerosis.
Flannery LD, Fahed AC, DeFaria Yeh D, Youniss MA, Barinsky GL, Stefanescu Schmidt AC, Benavidez OJ, Meigs JB, Bhatt AB
Frequency of Guideline-Based Statin Therapy in Adults With Congenital Heart Disease. Am J Cardiol. 2018 02 15; 121(4):485-490.
Frequency of Guideline-Based Statin Therapy in Adults With Congenital Heart Disease.
Kamar A, Fahed AC, Shibbani K, El-Hachem N, Bou-Slaiman S, Arabi M, Kurban M, Seidman JG, Seidman CE, Haidar R, Baydoun E, Nemer G, Bitar F
A Novel Role for CSRP1 in a Lebanese Family with Congenital Cardiac Defects. Front Genet. 2017; 8:217.
A Novel Role for CSRP1 in a Lebanese Family with Congenital Cardiac Defects.
Fahed AC, Shibbani K, Andary RR, Arabi MT, Habib RH, Nguyen DD, Haddad FF, Moubarak E, Nemer G, Azar ST, Bitar FF
Premature Valvular Heart Disease in Homozygous Familial Hypercholesterolemia. Cholesterol. 2017; 2017:3685265.
Premature Valvular Heart Disease in Homozygous Familial Hypercholesterolemia.