Mary Ellen Avery Associate Professor of Pediatrics in the Field of Newborn Medicine
Christou H, Connors JM, Ziotopoulou M, Hatzidakis V, Papathanassoglou E, Ringer SA, Mantzoros CS
The Journal of clinical endocrinology and metabolism
Cord blood leptin and insulin-like growth factor levels are independent predictors of fetal growth. J Clin Endocrinol Metab. 2001 Feb; 86(2):935-8.
Cord blood leptin and insulin-like growth factor levels are independent predictors of fetal growth.
The p38 mitogen-activated protein kinase pathway is involved in the regulation of heme oxygenase-1 by acidic extracellular pH in aortic smooth muscle cells. J Cell Biochem. 2008 Dec 01; 105(5):1298-306.
The p38 mitogen-activated protein kinase pathway is involved in the regulation of heme oxygenase-1 by acidic extracellular pH in aortic smooth muscle cells.
Current pharmacologic approaches for prevention and treatment of bronchopulmonary dysplasia. Int J Pediatr. 2012; 2012:598606.
Current pharmacologic approaches for prevention and treatment of bronchopulmonary dysplasia.
Intrauterine closure of the ductus arteriosus: implications for the neonatologist. Am J Perinatol. 2009 Aug; 26(7):473-8.
Intrauterine closure of the ductus arteriosus: implications for the neonatologist.
Sex hormones and vascular protection in pulmonary arterial hypertension. J Cardiovasc Pharmacol. 2010 Nov; 56(5):471-4.
Sex hormones and vascular protection in pulmonary arterial hypertension.
Liang X, Gupta K, Quintero JR, Cernadas M, Kobzik L, Christou H, Pier GB, Owen CA, Çataltepe S
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Macrophage FABP4 is required for neutrophil recruitment and bacterial clearance in Pseudomonas aeruginosa pneumonia. FASEB J. 2019 03; 33(3):3562-3574.
Macrophage FABP4 is required for neutrophil recruitment and bacterial clearance in Pseudomonas aeruginosa pneumonia.
Vitali SH, Mitsialis SA, Christou H, Fernandez-Gonzalez A, Liu X, Kourembanas S
Mechanisms of heme oxygenase-1-mediated cardiac and pulmonary vascular protection in chronic hypoxia: roles of carbon monoxide and bilirubin. Chest. 2005 Dec; 128(6 Suppl):578S-579S.
Mechanisms of heme oxygenase-1-mediated cardiac and pulmonary vascular protection in chronic hypoxia: roles of carbon monoxide and bilirubin.
Michael Z, Spyropoulos F, Ghanta S, Christou H
Bronchopulmonary Dysplasia: An Update of Current Pharmacologic Therapies and New Approaches. Clin Med Insights Pediatr. 2018; 12:1179556518817322.
Bronchopulmonary Dysplasia: An Update of Current Pharmacologic Therapies and New Approaches.
Christou H, Bailey N, Kluger MS, Mitsialis SA, Kourembanas S
American journal of physiology. Heart and circulatory physiology
Extracellular acidosis induces heme oxygenase-1 expression in vascular smooth muscle cells. Am J Physiol Heart Circ Physiol. 2005 Jun; 288(6):H2647-52.
Extracellular acidosis induces heme oxygenase-1 expression in vascular smooth muscle cells.
Vitali SH, Mitsialis SA, Liang OD, Liu X, Fernandez-Gonzalez A, Christou H, Wu X, McGowan FX, Kourembanas S
Divergent cardiopulmonary actions of heme oxygenase enzymatic products in chronic hypoxia. PLoS One. 2009 Jun 19; 4(6):e5978.
Divergent cardiopulmonary actions of heme oxygenase enzymatic products in chronic hypoxia.
Christou H, Dookeran N, Haas A, Di Frances C, Emans SJ, Milstein ME, Kram KE, Seely EW
MedEdPORTAL : the journal of teaching and learning resources
Establishing Effective Mentoring Networks: Rationale and Strategies. MedEdPORTAL. 2017 Apr 18; 13:10571.
Establishing Effective Mentoring Networks: Rationale and Strategies.
Hudalla H, Michael Z, Christodoulou N, Willis GR, Fernandez-Gonzalez A, Filatava EJ, Dieffenbach P, Fredenburgh LE, Stearman RS, Geraci MW, Kourembanas S, Christou H
American journal of respiratory cell and molecular biology
Carbonic Anhydrase Inhibition Ameliorates Inflammation and Experimental Pulmonary Hypertension. Am J Respir Cell Mol Biol. 2019 10; 61(4):512-524.
Carbonic Anhydrase Inhibition Ameliorates Inflammation and Experimental Pulmonary Hypertension.
Clement A. Smith Professor of Pediatrics
Lithoxopoulou M, Rallis D, Christou H, Goutsiou E, Varaklioti A, Karagianni P, Tsakalidis C, Domeyer P, Kuriakeli G, Soubasi V
Early caloric deprivation in preterm infants affects Bayley-III scales performance at 18-24 months of corrected age. Res Dev Disabil. 2019 Aug; 91:103429.
Early caloric deprivation in preterm infants affects Bayley-III scales performance at 18-24 months of corrected age.
DiPrisco B, Kumar A, Kalra B, Savjani GV, Michael Z, Farr O, Papathanasiou AE, Christou H, Mantzoros C
Placental proteases PAPP-A and PAPP-A2, the binding proteins they cleave (IGFBP-4 and -5), and IGF-I and IGF-II: Levels in umbilical cord blood and associations with birth weight and length. Metabolism. 2019 11; 100:153959.
Placental proteases PAPP-A and PAPP-A2, the binding proteins they cleave (IGFBP-4 and -5), and IGF-I and IGF-II: Levels in umbilical cord blood and associations with birth weight and length.
DiPrisco B, Kumar A, Kalra B, Savjani GV, Michael Z, Farr O, Papathanasiou AE, Christou H, Mantzoros CS
Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists
GLYCOSYLATED FIBRONECTIN AND INHIBIN ARE LOWER AND ANTI-MÜLLERIAN HORMONE IS HIGHER IN UMBILICAL CORD BLOOD WHEN MOTHERS HAVE PREECLAMPSIA. Endocr Pract. 2020 Mar; 26(3):318-327.
GLYCOSYLATED FIBRONECTIN AND INHIBIN ARE LOWER AND ANTI-MÜLLERIAN HORMONE IS HIGHER IN UMBILICAL CORD BLOOD WHEN MOTHERS HAVE PREECLAMPSIA.
Basak A, Munschauer M, Lareau CA, Montbleau KE, Ulirsch JC, Hartigan CR, Schenone M, Lian J, Wang Y, Huang Y, Wu X, Gehrke L, Rice CM, An X, Christou HA, Mohandas N, Carr SA, Chen JJ, Orkin SH, Lander ES, Sankaran VG
Control of human hemoglobin switching by LIN28B-mediated regulation of BCL11A translation. Nat Genet. 2020 02; 52(2):138-145.
Control of human hemoglobin switching by LIN28B-mediated regulation of BCL11A translation.
Spyropoulos F, Vitali SH, Touma M, Rose CD, Petty CR, Levy P, Kourembanas S, Christou H
Echocardiographic markers of pulmonary hemodynamics and right ventricular hypertrophy in rat models of pulmonary hypertension. Pulm Circ. 2020 Apr-Jun; 10(2):2045894020910976.
Echocardiographic markers of pulmonary hemodynamics and right ventricular hypertrophy in rat models of pulmonary hypertension.
Joung KE, Clausen D, Herdt A, Presti A, Snyder R, Peters C, Christou H, Mantzoros CS
Association of circulating FGF-21 levels in the first week of life and postnatal growth in hospitalized preterm infants. Metabol Open. 2020 Mar; 5:100030.
Association of circulating FGF-21 levels in the first week of life and postnatal growth in hospitalized preterm infants.
Papathanasiou AE, Spyropoulos F, Michael Z, Joung KE, Briana DD, Malamitsi-Puchner A, Mantzoros CS, Christou H
International journal of molecular sciences
Adipokines and Metabolic Regulators in Human and Experimental Pulmonary Arterial Hypertension. Int J Mol Sci. 2021 Feb 01; 22(3).
Adipokines and Metabolic Regulators in Human and Experimental Pulmonary Arterial Hypertension.
Niccum M, Spyropoulos F, Levin JC, Petty CR, Mullen MP, Christou H
Lower oxygen saturation targets in preterm infants are not associated with increased rates of pulmonary hypertension. J Neonatal Perinatal Med. 2021; 14(4):519-526.
Lower oxygen saturation targets in preterm infants are not associated with increased rates of pulmonary hypertension.
Christou H, Michael Z, Spyropoulos F, Chen Y, Rong D, Khalil RA
American journal of physiology. Regulatory, integrative and comparative physiology
Carbonic anhydrase inhibition improves pulmonary artery reactivity and nitric oxide-mediated relaxation in sugen-hypoxia model of pulmonary hypertension. Am J Physiol Regul Integr Comp Physiol. 2021 06 01; 320(6):R835-R850.
Carbonic anhydrase inhibition improves pulmonary artery reactivity and nitric oxide-mediated relaxation in sugen-hypoxia model of pulmonary hypertension.
Hansmann G, Christou H, Koestenberger M, Sallmon H
European journal of clinical investigation
Off-label use of PAH-targeted medications approved for adults and their financial coverage by health insurances are vital for children with pulmonary hypertension. Eur J Clin Invest. 2021 Aug; 51(8):e13571.
Off-label use of PAH-targeted medications approved for adults and their financial coverage by health insurances are vital for children with pulmonary hypertension.
Spyropoulos F, Michael Z, Finander B, Vitali S, Kosmas K, Zymaris P, Kalish BT, Kourembanas S, Christou H
Acetazolamide Improves Right Ventricular Function and Metabolic Gene Dysregulation in Experimental Pulmonary Arterial Hypertension. Front Cardiovasc Med. 2021; 8:662870.
Acetazolamide Improves Right Ventricular Function and Metabolic Gene Dysregulation in Experimental Pulmonary Arterial Hypertension.
Spyropoulos F, Sorrentino A, van der Reest J, Yang P, Waldeck-Weiermair M, Steinhorn B, Eroglu E, Saeedi Saravi SS, Yu P, Haigis M, Christou H, Michel T
Metabolomic and transcriptomic signatures of chemogenetic heart failure. Am J Physiol Heart Circ Physiol. 2022 03 01; 322(3):H451-H465.
Metabolomic and transcriptomic signatures of chemogenetic heart failure.
Shrestha S, Lamattina A, Pacheco-Rodriguez G, Ng J, Liu X, Sonawane A, Imani J, Qiu W, Kosmas K, Louis P, Hentschel A, Steagall WK, Onishi R, Christou H, Henske EP, Glass K, Perrella MA, Moss J, Tantisira K, El-Chemaly S
ETV2 regulates PARP-1 binding protein to induce ER stress-mediated death in tuberin-deficient cells. Life Sci Alliance. 2022 05; 5(5).
ETV2 regulates PARP-1 binding protein to induce ER stress-mediated death in tuberin-deficient cells.
Mechanisms of pulmonary vascular dysfunction in pulmonary hypertension and implications for novel therapies. Am J Physiol Heart Circ Physiol. 2022 05 01; 322(5):H702-H724.
Mechanisms of pulmonary vascular dysfunction in pulmonary hypertension and implications for novel therapies.
Abend N, Adams E, Al Balushi A, Alburaki W, Appendino J, Barbosa VS, Birca A, Bonifacio S, Branagan A, Chang T, Chowdhury R, Christou H, Chu C, Cilio MR, Comani S, Corsi-Cabrera M, Croce P, Cubero-Rego L, Dawoud F, de Vries L, Dehaes M, Devane D, Duncan A, El Ters N, El-Dib M, Elshibiny H, Esser M, Fairchild K, Finucane E, Franceschini MA, Gallagher A, Ghosh A, Glass H, Venkata SKRG, Baillet TH, Herzberg E, Hildrey E, Hurley T, Inder T, Jacobs E, Jefferies K, Jermendy A, Khazaei M, Kilmartin K, King G, Lauronen L, Lee S, Leijser L, Lind J, Llaguno NS, Machie M, Magalhães M, Mahdi Z, Maluomi J, Marandyuk B, Massey S, McCulloch C, Metsäranta M, Mikkonen K, Mohammad K, Molloy E, Momin S, Munster C, Murthy P, Netto A, Nevalainen P, Nguyen J, Nieves M, Nyman J, Oliver N, Peeters C, Pietrobom RFR, Pijpers J, Pinchefksy E, Ping YB, Quirke F, Raeisi K, Ricardo-Garcell J, Robinson J, Rodrigues DP, Rosati J, Scott J, Scringer-Wilkes M, Shellhaas R, Smit L, Soul J, Srivastava A, Steggerda S, Sunwoo J, Szakmar E, Tamburro G, Thomas S, Toiviainen-Salo S, Toma AI, Vanhatalo S, Variane GFT, Vein A, Vesoulis Z, Vilan A, Volpe J, Weeke L, Wintermark P, Wusthoff C, Zappasodi F, Zein H, Zempel J
Proceedings of the 13th International Newborn Brain Conference: Neonatal Neurocritical Care, Seizures, and Continuous EEG monitoring. J Neonatal Perinatal Med. 2022; 15(2):467-485.
Proceedings of the 13th International Newborn Brain Conference: Neonatal Neurocritical Care, Seizures, and Continuous EEG monitoring.
Gray MM, Bruno C, French H, Myers P, Carbajal MM, Reber KM, Christou H, Karpen H, Johnston LC
Changes, Challenges, and Variations in Neonatal-Perinatal Medicine Fellowship: A View from the Program Directors. Am J Perinatol. 2024 05; 41(S 01):e163-e173.
Changes, Challenges, and Variations in Neonatal-Perinatal Medicine Fellowship: A View from the Program Directors.
Pleiotropic Effects of Pyruvate Kinase M2 in Right Ventricular Failure and Pulmonary Arterial Hypertension. JACC Basic Transl Sci. 2022 Apr; 7(4):404-405.
Pleiotropic Effects of Pyruvate Kinase M2 in Right Ventricular Failure and Pulmonary Arterial Hypertension.
Kosmas K, Michael Z, Papathanasiou AE, Spyropoulos F, Adib E, Jasuja R, Christou H
Skeletal Muscle Dysfunction in Experimental Pulmonary Hypertension. Int J Mol Sci. 2022 Sep 18; 23(18).
Skeletal Muscle Dysfunction in Experimental Pulmonary Hypertension.
Babacheva E, Rallis D, Christou H, Mitsiakos G, Mikos T, Dampala K, Tsakalidis C, Kioumi A, Goulis DG, Soubasi V
Maternal diabetes and the role of neonatal reticulocyte hemoglobin content as a biomarker of iron status in the perinatal period. Front Endocrinol (Lausanne). 2022; 13:1011897.
Maternal diabetes and the role of neonatal reticulocyte hemoglobin content as a biomarker of iron status in the perinatal period.
Khurana J, Orbach DB, Gauvreau K, Collins SL, Tella JB, Agrawal PB, Christou HA, Mullen MP
Pulmonary Hypertension in Infants and Children with Vein of Galen Malformation and Association with Clinical Outcomes. J Pediatr. 2023 07; 258:113404.
Pulmonary Hypertension in Infants and Children with Vein of Galen Malformation and Association with Clinical Outcomes.
Ali S, Altamimi T, Annink K, Bartmann P, Beato N, Belker K, Ben-David D, Benders M, Bhattacharya S, Anbu Chakkarapani A, Anbu Chakkarapani A, Charbonneau L, Cherkerzian S, Chowdhury RA, Christou H, de Ribaupierre D, Dehaes M, Domogalla C, Duerden EG, El-Dib M, Elanbari M, Elshibiny H, Engel C, Felderhoff U, Flemmer AW, Franceschini MA, Franz A, Garvey A, Groenendaal F, Gupta S, Hannon K, Hellström-Westas L, Herber-Jonat S, Holz S, Hüning B, Inder T, Jamil A, Jilson T, Kebaya LMN, Keller M, Khalifa AKM, Kim SH, Kittel J, Koch L, Kowalczyk A, Kühr J, St Lawrence K, Lee S, Marandyuk B, Marlow N, Mayorga PC, Meyer R, Meyerink P, Miró J, More K, Munk A, Munster C, Musabi M, Nuyt AM, Peters J, Plum A, Poirier N, Pöschl J, Raboisson MJ, Robinson J, Roychaudhuri S, Rüdiger M, Sarközy G, Saugstad OD, Segerer H, Soni N, Stein A, Steins-Rang C, Sunwoo J, Szakmar E, Tang L, Taskin E, Vahidi H, Waldherr S, Wieg C, Winkler S, Wu R, Yajamanyam PK, Yapicioglu-Yildizdas H
Proceedings of the 14th International Newborn Brain Conference: Other forms of brain monitoring, such as NIRS, fMRI, biochemical, etc. J Neonatal Perinatal Med. 2023; 16(s1):S63-S73.
Proceedings of the 14th International Newborn Brain Conference: Other forms of brain monitoring, such as NIRS, fMRI, biochemical, etc.
Rallis D, Ben-David D, Woo K, Robinson J, Beadles D, Spyropoulos F, Christou H, Cataltepe S
Journal of perinatology : official journal of the California Perinatal Association
Predictors of successful extubation from volume-targeted ventilation in extremely preterm neonates. J Perinatol. 2024 02; 44(2):250-256.
Predictors of successful extubation from volume-targeted ventilation in extremely preterm neonates.
Pneumoprotein CC16 in the Umbilical Cord Blood of Preterm Neonates. Am J Perinatol. 2024 05; 41(S 01):e3367-e3373.
Pneumoprotein CC16 in the Umbilical Cord Blood of Preterm Neonates.
Rallis D, Ben-David D, Woo K, Robinson J, Beadles D, Bernardini L, Abdulhayoglu E, Flanigan E, Christou H
Single center experience with first-intention high-frequency jet vs. volume-targeted ventilation in extremely preterm neonates. Front Pediatr. 2023; 11:1326668.
Single center experience with first-intention high-frequency jet vs. volume-targeted ventilation in extremely preterm neonates.
Kim H, Liu Y, Kim J, Kim Y, Klouda T, Fisch S, Baek SH, Liu T, Dahlberg S, Hu CJ, Tian W, Jiang X, Kosmas K, Christou HA, Korman BD, Vargas SO, Wu JC, Stenmark KR, Perez VJ, Nicolls MR, Raby BA, Yuan K
Pericytes contribute to pulmonary vascular remodeling via HIF2a signaling. EMBO Rep. 2024 Feb; 25(2):616-645.
Pericytes contribute to pulmonary vascular remodeling via HIF2a signaling.
Maternal Obesity Modulates Cord Blood Concentrations of Proprotein Convertase Subtilisin/Kexin-type 9 Levels. J Endocr Soc. 2024 Feb 19; 8(4):bvae031.
Maternal Obesity Modulates Cord Blood Concentrations of Proprotein Convertase Subtilisin/Kexin-type 9 Levels.
Spyropoulos F, Das AA, Waldeck-Weiermair M, Yadav S, Pandey AK, Guo R, Covington TA, Thulabandu V, Kosmas K, Steinhorn B, Perrella MA, Liu X, Christou H, Michel T
Adult and neonatal models of chemogenetic heart failure caused by oxidative stress. J Clin Invest. 2024 Mar 14; 134(9).
Adult and neonatal models of chemogenetic heart failure caused by oxidative stress.
Acun C, Akugizibwe C, Aly H, Avian AA, Aycan N, Baik-Schneditz N, Bailey S, Balog V, Barra M, Bartolini E, Basaranoglu M, Bauerstätter P, Bazan A, Berger A, Boardman JP, Boylan G, Bruckner M, Bua J, Buchmayer J, Caprio M, Cherkerzian S, Chirumammilla V, Christou H, Demir DC, Dempsey EM, El-Dib M, Elis J, El-Shibiny H, Emurang I, Esser MJ, Figueroa G, Finn D, Franceschini MA, Fuchs H, Garvey A, Giordano V, Goeral K, Goldstein S, Govindan RB, Grant E, Gründler K, Hammer M, Hannon K, Hauser B, Hsiao CH, Ilahi I, Inder T, Jermendy A, De Jesus P, Kabachelor EM, Kainja E, Karaman S, Karnati S, Karpinski L, Kasprian G, Katugi MK, Khan J, Kiechl-Kohlendorfer U, Kim SH, Kis-Tamas M, Klebermass-Schrehof K, Klein L, Kornhauser-Cerar L, Langs G, Bogner LL, Lavu R, Law B, Lin PY, Lista G, Liu W, Livingstone V, Magombe J, Mathieson S, Mileder L, Mohammad K, Moore M, Mulondo R, Munster C, Murray D, Nalule E, Natukwatsa D, Nicoletti N, Nöhammer C, Nuzum T, Ochieng S, O'Donnell M, Olischar M, Orlandi S, O'Toole J, Paltrinieri AL, Pardo A, Pavel A, Perme T, Pfurtscheller D, Pichler G, Pleau C, Pradas AL, Pusil S, Puthuraya S, Rajaram A, Rallis D, Ramírez B, Randhawa A, Robertson NJ, Pusil S, Schiff S, Schlatterer S, Schlatzer C, Schmölzer GM, Schönthaler S, Schwaberger B, Schwarz CE, Seruwu M, Springer L, Steiner M, Stucchi I, Sunwoo J, Sutin J, Szabo M, Szakmar E, Szczapa T, Tatz J, Tindimwebwa S, Trinh SH, Tuncer O, Turner HL, Urlesberger B, Vierlinger K, Vignolle GA, Vyas R, Wabukoma M, Wachtel E, Warf B, Woglom M, Wolfsberger CH, Woodward K, Yurekturk E
Proceedings of the 15th International Newborn Brain Conference: Other forms of brain monitoring, such as NIRS, fMRI, biochemical, etc. J Neonatal Perinatal Med. 2024; 17(3):S393-S419.
Proceedings of the 15th International Newborn Brain Conference: Other forms of brain monitoring, such as NIRS, fMRI, biochemical, etc.
Abdi K, Adams E, Agarwal S, Aliyu MH, Altamimi T, Andescavage N, Aral A, Arfi H, Armour E, Armstrong L, Mulkey SB, Bambi J, Basu S, Beaulieu LBO, Belfort M, Bell K, Benner E, Bernard C, Bhattacharya S, Biselele T, Bitar L, Blaz W, Bolay H, Bray M, Bruckert L, Busnelli A, Mayorga PC, Carrasco M, Carter E, Cassidy M, Chalak L, Chao A, Chauhan P, Cherkerzian S, Chernova L, Chowdhury R, Christou H, Ciralli F, Coletti M, Comanducci A, Comstock B, Cooke A, Cornet MC, Corsi-Cabrera M, Coscia A, Côte-Corriveau G, Cubero-Rego AC, Cubero-Rego MLA, Cuddyer D, Cuzzilla R, Cuzzilla R, Dehaes M, Doyle E, Drobyshevsky A, Dubner S, Duerden EG, Dunne A, DuPlessis A, Eisch AJ, El-Dib M, Elmazoglu Z, Emrick L, Epstein A, Erdei C, Ergun MA, Fedeles B, Feldman H, Findley T, Flynn P, Gadra E, Gagnon MM, Gagnon M, Ganesh P, Gano D, Garbarini F, Geary M, Ghezzi E, Gibson K, Glass H, Gloire GM, Gonzalez F, Gorman A, Goswami I, Gregory S, Gulnerman EK, Harmony T, Harrington L, Harshbarger J, Hartley C, Hayakawa M, Hayes B, Heagerty P, Hicks M, Inder T, Iragavarapu M, Ito Y, Jain V, Johnson KJD, Joseph D, Jurkiewicz M, Juul S, Kamyshanskiy Y, Kapoor B, Kapse K, Kazan HH, Kebaya L, Kidokoro H, Klein R, Kling E, Kopobayeva I, Korf J, Kumai S, Lazarus M, Lebane D, Lee I, Lemmon M, Leon R, Limperopoulos C, Liu E, Liu YL, Ognean ML, Luu TM, Machie M, Marchant S, Marchman V, Marsh E, Martinez-Biarge M, Matacuta I, Matei C, Maxfield C, Mayock D, McCullough L, Meyerink P, Miller K, Millman R, Minga S, Mitsumatsu T, Monsell S, Moulton TS, Murnick J, Nakata T, Narita H, Natsume J, Nichols ES, Nicolayevsky SE, Nuyt AM, O'Brien J, Ostrander B, Pacheco J, Pagano L, Pardo A, Peila C, Peyton C, Peyton C, Pineda R, Poblaciones R, Poles K, Quigley M, Reddy S, Remis S, Reynolds A, Ribaupierre S, Ricardo-Garcell J, Rikard B, Rodriguez B, Ronga I, Rosenberg P, Ross M, Roychaudhuri S, Russo S, Sadowska-Krawczenko I, Salihu HM, Sato Y, Saulino P, Sawamura F, Scala M, Scher M, Schindewolf E, Sebastiano AR, Shanahan J, Sharon D, Sheldon Y, Shiraki A, Simard MN, Singh E, Sirgiovanni I, Smego A, Steele T, Stein N, Suttin R, Suzui R, Swider M, Tady BP, Taga G, Tang S, Tarrant A, Tarui T, Topa EGA, Trapp N, Tristao L, Tuka D, Turdybekova Y, Ushida T, Usman F, Venkatesan C, Visa G, Wang J, Watanabe H, Watson T, Witulska-Alagöz A, Wood S, Wu Y, Yamamoto H, Yarnykh V, Young M, Yun NY, Zapolnik P, Zarrinnegar D
Proceedings of the 15th International Newborn Brain Conference: Fetal and/or neonatal brain development, both normal and abnormal. J Neonatal Perinatal Med. 2024; 17(3):S285-S316.
Proceedings of the 15th International Newborn Brain Conference: Fetal and/or neonatal brain development, both normal and abnormal.
An update on pharmacologic approaches to bronchopulmonary dysplasia. Semin Perinatol. 2013 Apr; 37(2):115-23.
An update on pharmacologic approaches to bronchopulmonary dysplasia.
Xiao Y, Christou H, Liu L, Visner G, Mitsialis SA, Kourembanas S, Liu H
American journal of respiratory and critical care medicine
Endothelial indoleamine 2,3-dioxygenase protects against development of pulmonary hypertension. Am J Respir Crit Care Med. 2013 Aug 15; 188(4):482-91.
Endothelial indoleamine 2,3-dioxygenase protects against development of pulmonary hypertension.
Kosmas K, Papathanasiou AE, Spyropoulos F, Rehman R, Cunha AA, Fredenburgh LE, Perrella MA, Christou H
Stress Granule Assembly in Pulmonary Arterial Hypertension. Cells. 2024 10 30; 13(21).
Stress Granule Assembly in Pulmonary Arterial Hypertension.
Rallis D, El-Shibiny H, Szakmar E, Garvey A, Christou H, El-Dib M
Impact of persistent pulmonary hypertension on cerebral oxygenation in infants with neonatal encephalopathy. Pediatr Res. 2025 Jul; 98(1):203-209.
Impact of persistent pulmonary hypertension on cerebral oxygenation in infants with neonatal encephalopathy.
Rallis D, Christou H, Abdulhayoglu E, El-Dib M
A narrative review of the clinical applications of renal NIRS and integration with cerebral NIRS in the NICU. J Perinatol. 2025 Dec; 45(12):1655-1663.
A narrative review of the clinical applications of renal NIRS and integration with cerebral NIRS in the NICU.
Rehman R, Dieffenbach P, Vellarikkal SK, Corcoran AM, Pomales L, Arciniegas Rubio A, Zambrano Vera KV, Spyropoulos F, Kosmas K, Lam H, Filippakis H, Perrella MA, Fredenburgh LE, Christou H
PINK1/Parkin Deficiency Enhances Vascular Remodeling and Aggravates Hypoxia-induced Pulmonary Hypertension. Am J Respir Cell Mol Biol. 2025 Dec; 73(6):859-870.
PINK1/Parkin Deficiency Enhances Vascular Remodeling and Aggravates Hypoxia-induced Pulmonary Hypertension.
Joung KE, Christou H, Park KH, Mantzoros CS
Cord blood levels of osteopontin as a phenotype marker of gestational age and neonatal morbidities. Obesity (Silver Spring). 2014 May; 22(5):1317-24.
Cord blood levels of osteopontin as a phenotype marker of gestational age and neonatal morbidities.
Burris HH, Van Marter LJ, McElrath TF, Tabatabai P, Litonjua AA, Weiss ST, Christou H
Vitamin D status among preterm and full-term infants at birth. Pediatr Res. 2014 Jan; 75(1-1):75-80.
Vitamin D status among preterm and full-term infants at birth.
Proceedings of the 15th International Newborn Brain Conference: Fetal and/or neonatal brain development, both normal and abnormal: Fota Island, Cork, Ireland, February 28th - March 2nd 2024. J Neonatal Perinatal Med. 2024 Aug 05; 17(3):S285-S316.
Proceedings of the 15th International Newborn Brain Conference: Fetal and/or neonatal brain development, both normal and abnormal: Fota Island, Cork, Ireland, February 28th - March 2nd 2024.
Proceedings of the 15th International Newborn Brain Conference: Other forms of brain monitoring, such as NIRS, fMRI, biochemical, etc.: Fota Island, Cork, Ireland, February 28th - March 2nd 2024. J Neonatal Perinatal Med. 2024 Aug 05; 17(3):S393-S419.
Proceedings of the 15th International Newborn Brain Conference: Other forms of brain monitoring, such as NIRS, fMRI, biochemical, etc.: Fota Island, Cork, Ireland, February 28th - March 2nd 2024.
Tsoyi K, Geldart AM, Christou H, Liu X, Chung SW, Perrella MA
Elk-3 is a KLF4-regulated gene that modulates the phagocytosis of bacteria by macrophages. J Leukoc Biol. 2015 Jan; 97(1):171-80.
Elk-3 is a KLF4-regulated gene that modulates the phagocytosis of bacteria by macrophages.
Lin T, Maita D, Thundivalappil SR, Riley FE, Hambsch J, Van Marter LJ, Christou HA, Berra L, Fagan S, Christiani DC, Warren HS
Hemopexin in severe inflammation and infection: mouse models and human diseases. Crit Care. 2015 Apr 15; 19:166.
Hemopexin in severe inflammation and infection: mouse models and human diseases.
Joung KE, Park KH, Filippaios A, Dincer F, Christou H, Mantzoros CS
Cord blood irisin levels are positively correlated with birth weight in newborn infants. Metabolism. 2015 Nov; 64(11):1507-14.
Cord blood irisin levels are positively correlated with birth weight in newborn infants.
Vascular smooth muscle cell phenotypic switching in Pulmonary Hypertension
The Pathomechanistic Role of Endothelial IDO in proliferative Retinopathy
THE ROLE OF CARBON MONOXIDE IN VASCULAR HOMEOSTASIS
Joung KE, Burris HH, Van Marter LJ, McElrath TF, Michael Z, Tabatabai P, Litonjua AA, Weiss ST, Christou H
Vitamin D and bronchopulmonary dysplasia in preterm infants. J Perinatol. 2016 10; 36(10):878-82.
Vitamin D and bronchopulmonary dysplasia in preterm infants.
Christou H, Dizon ML, Farrow KN, Jadcherla SR, Leeman KT, Maheshwari A, Rubin LP, Stansfield BK, Rowitch DH
Sustaining careers of physician-scientists in neonatology and pediatric critical care medicine: formulating supportive departmental policies. Pediatr Res. 2016 11; 80(5):635-640.
Sustaining careers of physician-scientists in neonatology and pediatric critical care medicine: formulating supportive departmental policies.
Department of Pediatrics/Division of Newborn Medicine
Kourembanas S, Morita T, Liu Y, Christou H
Mechanisms by which oxygen regulates gene expression and cell-cell interaction in the vasculature. Kidney Int. 1997 Feb; 51(2):438-43.
Mechanisms by which oxygen regulates gene expression and cell-cell interaction in the vasculature.
Christou H, Adatia I, Van Marter LJ, Kane JW, Thompson JE, Stark AR, Wessel DL, Kourembanas S
Effect of inhaled nitric oxide on endothelin-1 and cyclic guanosine 5'-monophosphate plasma concentrations in newborn infants with persistent pulmonary hypertension. J Pediatr. 1997 Apr; 130(4):603-11.
Effect of inhaled nitric oxide on endothelin-1 and cyclic guanosine 5'-monophosphate plasma concentrations in newborn infants with persistent pulmonary hypertension.
Christou H, Van Marter LJ, Wessel DL, Allred EN, Kane JW, Thompson JE, Stark AR, Kourembanas S
Inhaled nitric oxide reduces the need for extracorporeal membrane oxygenation in infants with persistent pulmonary hypertension of the newborn. Crit Care Med. 2000 Nov; 28(11):3722-7.
Inhaled nitric oxide reduces the need for extracorporeal membrane oxygenation in infants with persistent pulmonary hypertension of the newborn.
Joung KE, Cataltepe SU, Michael Z, Christou H, Mantzoros CS
Cord Blood Adipocyte Fatty Acid-Binding Protein Levels Correlate With Gestational Age and Birth Weight in Neonates. J Clin Endocrinol Metab. 2017 05 01; 102(5):1606-1613.
Cord Blood Adipocyte Fatty Acid-Binding Protein Levels Correlate With Gestational Age and Birth Weight in Neonates.
Minamino T, Christou H, Hsieh CM, Liu Y, Dhawan V, Abraham NG, Perrella MA, Mitsialis SA, Kourembanas S
Proceedings of the National Academy of Sciences of the United States of America
Targeted expression of heme oxygenase-1 prevents the pulmonary inflammatory and vascular responses to hypoxia. Proc Natl Acad Sci U S A. 2001 Jul 17; 98(15):8798-803.
Targeted expression of heme oxygenase-1 prevents the pulmonary inflammatory and vascular responses to hypoxia.
Anttila V, Christou H, Hagino I, Iwata Y, Mettler BA, Fernandez-Gonzalez A, Zurakowski D, Jonas RA
Cerebral endothelial nitric oxide synthase expression is reduced after very-low-flow bypass. Ann Thorac Surg. 2006 Jun; 81(6):2202-6.
Cerebral endothelial nitric oxide synthase expression is reduced after very-low-flow bypass.
Yet SF, Perrella MA, Layne MD, Hsieh CM, Maemura K, Kobzik L, Wiesel P, Christou H, Kourembanas S, Lee ME
Hypoxia induces severe right ventricular dilatation and infarction in heme oxygenase-1 null mice. J Clin Invest. 1999 Apr; 103(8):R23-9.
Hypoxia induces severe right ventricular dilatation and infarction in heme oxygenase-1 null mice.
Hossain T, Kappelman MD, Perez-Atayde AR, Young GJ, Huttner KM, Christou H
Primary ciliary dyskinesia as a cause of neonatal respiratory distress: implications for the neonatologist. J Perinatol. 2003 Dec; 23(8):684-7.
Primary ciliary dyskinesia as a cause of neonatal respiratory distress: implications for the neonatologist.
Mam V, Tanbe AF, Vitali SH, Arons E, Christou HA, Khalil RA
The Journal of pharmacology and experimental therapeutics
Impaired vasoconstriction and nitric oxide-mediated relaxation in pulmonary arteries of hypoxia- and monocrotaline-induced pulmonary hypertensive rats. J Pharmacol Exp Ther. 2010 Feb; 332(2):455-62.
Impaired vasoconstriction and nitric oxide-mediated relaxation in pulmonary arteries of hypoxia- and monocrotaline-induced pulmonary hypertensive rats.
Current concepts in intrauterine growth restriction. J Intensive Care Med. 2004 Nov-Dec; 19(6):307-19.
Current concepts in intrauterine growth restriction.
Kourembanas S, Morita T, Christou H, Liu Y, Koike H, Brodsky D, Arthur V, Mitsial SA
Hypoxic responses of vascular cells. Chest. 1998 Jul; 114(1 Suppl):25S-28S.
Christou H, Morita T, Hsieh CM, Koike H, Arkonac B, Perrella MA, Kourembanas S
Prevention of hypoxia-induced pulmonary hypertension by enhancement of endogenous heme oxygenase-1 in the rat. Circ Res. 2000 Jun 23; 86(12):1224-9.
Prevention of hypoxia-induced pulmonary hypertension by enhancement of endogenous heme oxygenase-1 in the rat.
Pharmacological strategies in the prevention and management of bronchopulmonary dysplasia. Semin Perinatol. 2006 Aug; 30(4):209-18.
Pharmacological strategies in the prevention and management of bronchopulmonary dysplasia.
Brenninkmeijer L, Kuehl C, Geldart AM, Arons E, Christou H
Heme oxygenase-1 does not mediate the effects of extracellular acidosis on vascular smooth muscle cell proliferation, migration, and susceptibility to apoptosis. J Vasc Res. 2011; 48(4):285-96.
Heme oxygenase-1 does not mediate the effects of extracellular acidosis on vascular smooth muscle cell proliferation, migration, and susceptibility to apoptosis.
Waisbren SE, Bowles H, Hasan T, Zou KH, Emans SJ, Goldberg C, Gould S, Levine D, Lieberman E, Loeken M, Longtine J, Nadelson C, Patenaude AF, Quinn D, Randolph AG, Solet JM, Ullrich N, Walensky R, Weitzman P, Christou H
Gender differences in research grant applications and funding outcomes for medical school faculty. J Womens Health (Larchmt). 2008 Mar; 17(2):207-14.
Gender differences in research grant applications and funding outcomes for medical school faculty.
Christou H, Hudalla H, Michael Z, Filatava EJ, Li J, Zhu M, Possomato-Vieira JS, Dias-Junior C, Kourembanas S, Khalil RA
Impaired Pulmonary Arterial Vasoconstriction and Nitric Oxide-Mediated Relaxation Underlie Severe Pulmonary Hypertension in the Sugen-Hypoxia Rat Model. J Pharmacol Exp Ther. 2018 02; 364(2):258-274.
Impaired Pulmonary Arterial Vasoconstriction and Nitric Oxide-Mediated Relaxation Underlie Severe Pulmonary Hypertension in the Sugen-Hypoxia Rat Model.
Angelidou A, Michael Z, Hotz A, Friedman K, Emani S, LaRovere K, Christou H
Is There More to Zika? Complex Cardiac Disease in a Case of Congenital Zika Syndrome. Neonatology. 2018; 113(2):177-182.
Is There More to Zika? Complex Cardiac Disease in a Case of Congenital Zika Syndrome.
Christou H, Reslan OM, Mam V, Tanbe AF, Vitali SH, Touma M, Arons E, Mitsialis SA, Kourembanas S, Khalil RA
American journal of physiology. Lung cellular and molecular physiology
Improved pulmonary vascular reactivity and decreased hypertrophic remodeling during nonhypercapnic acidosis in experimental pulmonary hypertension. Am J Physiol Lung Cell Mol Physiol. 2012 May 01; 302(9):L875-90.
Improved pulmonary vascular reactivity and decreased hypertrophic remodeling during nonhypercapnic acidosis in experimental pulmonary hypertension.
Christou H, Yoshida A, Arthur V, Morita T, Kourembanas S
Increased vascular endothelial growth factor production in the lungs of rats with hypoxia-induced pulmonary hypertension. Am J Respir Cell Mol Biol. 1998 Jun; 18(6):768-76.
Increased vascular endothelial growth factor production in the lungs of rats with hypoxia-induced pulmonary hypertension.
Leptin in relation to growth and developmental processes in the fetus. Semin Reprod Med. 2002 May; 20(2):123-30.
Leptin in relation to growth and developmental processes in the fetus.
Lung injury and bronchopulmonary dysplasia in newborn infants. J Intensive Care Med. 2005 Mar-Apr; 20(2):76-87.
Lung injury and bronchopulmonary dysplasia in newborn infants.
Liu Y, Christou H, Morita T, Laughner E, Semenza GL, Kourembanas S
Carbon monoxide and nitric oxide suppress the hypoxic induction of vascular endothelial growth factor gene via the 5' enhancer. J Biol Chem. 1998 Jun 12; 273(24):15257-62.
Carbon monoxide and nitric oxide suppress the hypoxic induction of vascular endothelial growth factor gene via the 5' enhancer.
Christou H, Magnani B, Morse DS, Allred EN, Van Marter LJ, Wessel DL, Kourembanas S
Inhaled nitric oxide does not affect adenosine 5'-diphosphate-dependent platelet activation in infants with persistent pulmonary hypertension of the newborn. Pediatrics. 1998 Dec; 102(6):1390-3.
Inhaled nitric oxide does not affect adenosine 5'-diphosphate-dependent platelet activation in infants with persistent pulmonary hypertension of the newborn.
Scheid A, Borriello F, Pietrasanta C, Christou H, Diray-Arce J, Pettengill MA, Joshi S, Li N, Bergelson I, Kollmann T, Dowling DJ, Levy O
Adjuvant Effect of Bacille Calmette-Guérin on Hepatitis B Vaccine Immunogenicity in the Preterm and Term Newborn. Front Immunol. 2018; 9:29.
Adjuvant Effect of Bacille Calmette-Guérin on Hepatitis B Vaccine Immunogenicity in the Preterm and Term Newborn.