Chen, Xiqun
current student opportunities: Genetic connections between Parkinson's disease and cancer
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last name: Chen
coauthor of: Schwarzschild, Michael
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selected publications: Authorship 487078
research areas: Environmental Policy
research areas: Transportation
research areas: Carbon
research areas: Mesencephalon
research areas: Tyrosine 3-Monooxygenase
mailing address: 114 16th Street
positions: Associate Professor of Neurology
phone: 617/724-9611
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Efficient determination of purine metabolites in brain tissue and serum by high-performance liquid chromatography with electrochemical and UV detection.
PubMed Identifier: 22674671
author list: Burdett TC, Desjardins CA, Logan R, McFarland NR, Chen X, Schwarzschild MA
published in: Biomedical chromatography : BMC
information resource reference: Efficient determination of purine metabolites in brain tissue and serum by high-performance liquid chromatography with electrochemical and UV detection. Biomed Chromatogr. 2013 Jan; 27(1):122-9.
journal title abbreviation: Biomed Chromatogr
publication date: 2012-06-05T00:00:00
year: 2012
type: Academic Article
type: Article
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Neurotrophic effects of serum- and glucocorticoid-inducible kinase on adult murine mesencephalic dopamine neurons.
PubMed Identifier: 22895713
author list: Chen X, Tagliaferro P, Kareva T, Yarygina O, Kholodilov N, Burke RE
published in: The Journal of neuroscience : the official journal of the Society for Neuroscience
information resource reference: Neurotrophic effects of serum- and glucocorticoid-inducible kinase on adult murine mesencephalic dopamine neurons. J Neurosci. 2012 Aug 15; 32(33):11299-308.
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Tyrosine 3-Monooxygenase
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Mesencephalon
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Carbon
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Neurology
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Harvard T.H. Chan School of Public Health
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Massachusetts General Hospital
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Schwarzschild, Michael
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Isacson, Ole
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Dzhala, Volodymyr
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Kegel, Kimberly
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Tanzi, Rudolph
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Zhang, Can
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Ascherio, Alberto
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Suh, Jaehong
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Joseph P. and Rose F. Kennedy Professor of Child Neurology and Mental Retardation
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Assistant Professor of Neurology
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linked information resource: Neurotrophic effects of serum- and glucocorticoid-inducible kinase on adult murine mesencephalic dopamine neurons.

Authorship 199831
type: Authorship
author rank in publication: 5
linked author: Chen, Xiqun
linked information resource: Efficient determination of purine metabolites in brain tissue and serum by high-performance liquid chromatography with electrochemical and UV detection.

Authorship 1415866
type: Authorship
author rank in publication: 6
linked author: Chen, Xiqun
linked information resource: Exploring impacts of COVID-19 on city-wide taxi and ride-sourcing markets: Evidence from Ningbo, China.

Exploring impacts of COVID-19 on city-wide taxi and ride-sourcing markets: Evidence from Ningbo, China.
PubMed Identifier: 34840441
author list: Yu J, Xie N, Zhu J, Qian Y, Zheng S, Chen XM
published in: Transport policy
information resource reference: Exploring impacts of COVID-19 on city-wide taxi and ride-sourcing markets: Evidence from Ningbo, China. Transp Policy (Oxf). 2022 Jan; 115:220-238.
journal title abbreviation: Transp Policy (Oxf)
publication date: 2021-11-22T00:00:00
year: 2021
type: Academic Article
type: Article
type: Document
type: Information Resource

Genetic connections between Parkinson's disease and cancer
end date: 2026-10-30T00:00:00
start date: 2021-10-01T00:00:00
type: Mentoring - Current Student Opportunity
overview: Although Parkinson's disease (PD) and cancer are defined pathologically by neuron loss and cell overgrowth, respectively, they have been linked to some of the same gene alterations. LRRK2 mutations, the most common cause of autosomal dominant late-onset PD, are associated with an increased risk of cancer. Mutations of Parkin, a potent tumor suppressor gene, are the most common cause of autosomal recessive early-onset PD. While advances in cancer immunology are revolutionizing the treatment of cancer, there is a growing appreciation of the role of the immune system in PD. Previous and our preliminary studies support that PD and cancer-related LRRK2 and Parkin alterations can lead to dysregulated immune responses. The overall goal of the proposed study is to investigate whether and how the genetic connections between PD and cancer alter immune tolerance to dopaminergic neurons and contribute to dopaminergic neurodegeneration at the cellular, tissue, and systemic levels and in patient samples. Two specific aims will be pursued to determine whether 1) LRRK2 and Parkin alterations reprogram immune responses against dopaminergic neurons; 2) cancer-educated immune system alters dopaminergic-specific autoimmunity. Backed by exceptional expertise and resources from cancer research and neuroscience, two major disciplines that rarely crosstalk, our work strikes a balance between high risk and high return to address issues relevant to "Biology of PD-associated Genes" and "Neuro-immune Interactions". Its findings are expected to advance our understanding of the molecular events in the immune system leading to tumorigenesis in dividing cells and neurodegeneration as part of the systemic disorders in response to the same genetic triggers. These molecular insights would open new avenues for prevention and therapies for PD by offering a range of therapeutic targets, as well as the possibility that immune approaches developed in cancer will find applications in PD.
webpage: https://connects.catalyst.harvard.edu/profiles/studentopportunities/Detail

Assistant Professor of Neurology
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Associate Professor of Neurology
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position in organization: Massachusetts General Hospital

Salas, Renee
eCommons Login: RS310
first name: Renee
last name: Salas
full name: Renee Nicole Salas, M.D.
has faculty rank: Assistant Professor
photo: https://connects.catalyst.harvard.edu/Profiles/profile/Modules/CustomViewPersonGeneralInfo/PhotoHandler.ashx
Person ID: 119739
person in primary position: Assistant Professor of Emergency Medicine
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Authorship 1583249
type: Authorship
author rank in publication: 15
linked author: Chen, Xiqun
linked information resource: Understanding common human driving semantics for autonomous vehicles.

Understanding common human driving semantics for autonomous vehicles.
PubMed Identifier: 37521046
author list: Xia Y, Geng M, Chen Y, Sun S, Liao C, Zhu Z, Li Z, Ochieng WY, Angeloudis P, Elhajj M, Zhang L, Zeng Z, Zhang B, Gao Z, Chen XM
published in: Patterns (New York, N.Y.)
information resource reference: Understanding common human driving semantics for autonomous vehicles. Patterns (N Y). 2023 Jul 14; 4(7):100730.
journal title abbreviation: Patterns (N Y)
publication date: 2023-04-18T00:00:00
year: 2023
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1608593
type: Authorship
author rank in publication: 3
linked author: Chen, Xiqun
linked information resource: A multi-scale unified model of human mobility in urban agglomerations.

Authorship 1608592
type: Authorship
author rank in publication: 2
linked author: Chen, Xiqun
linked information resource: Meet the authors: Yong Chen, Xiqun (Michael) Chen, and Ziyou Gao.

Meet the authors: Yong Chen, Xiqun (Michael) Chen, and Ziyou Gao.
PubMed Identifier: 38035187
author list: Chen Y, Chen XM, Gao Z
published in: Patterns (New York, N.Y.)
information resource reference: Meet the authors: Yong Chen, Xiqun (Michael) Chen, and Ziyou Gao. Patterns (N Y). 2023 Nov 10; 4(11):100877.
journal title abbreviation: Patterns (N Y)
publication date: 2023-11-10T00:00:00
year: 2023
type: Academic Article
type: Article
type: Document
type: Information Resource

A multi-scale unified model of human mobility in urban agglomerations.
PubMed Identifier: 38035194
author list: Chen Y, Xu H, Chen XM, Gao Z
published in: Patterns (New York, N.Y.)
information resource reference: A multi-scale unified model of human mobility in urban agglomerations. Patterns (N Y). 2023 Nov 10; 4(11):100862.
journal title abbreviation: Patterns (N Y)
publication date: 2023-10-17T00:00:00
year: 2023
type: Academic Article
type: Article
type: Document
type: Information Resource

Assistant Professor of Emergency Medicine
is primary position: true
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position in division: https://connects.catalyst.harvard.edu/Profiles/profile/1229413
sort order: 1
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HR job title: Assistant Professor of Emergency Medicine
position in organization: Massachusetts General Hospital

Professor of Neurology
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sort order: 1
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HR job title: Professor of Neurology
position in organization: Massachusetts General Hospital

Professor of Medicine
is primary position: true
position in department: Medicine
position in division: Rheumatology
sort order: 1
type: Position
HR job title: Professor of Medicine
position in organization: Massachusetts General Hospital

Assistant Professor of Neurology
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position in department: Neurology
position in division: https://connects.catalyst.harvard.edu/Profiles/profile/1229413
sort order: 1
type: Position
HR job title: Assistant Professor of Neurology
position in organization: Massachusetts General Hospital

Associate Professor of Neurology
is primary position: true
position in department: Neurology
position in division: https://connects.catalyst.harvard.edu/Profiles/profile/1229413
sort order: 1
type: Position
HR job title: Associate Professor of Neurology
position in organization: Massachusetts General Hospital

Authorship 1677379
type: Authorship
author rank in publication: 2
linked author: Chen, Xiqun
linked information resource: Toward equitable, transparent, and collaborative human mobility computing for smart cities.

Toward equitable, transparent, and collaborative human mobility computing for smart cities.
PubMed Identifier: 39100961
author list: Chen Y, Chen XM, Gao Z
published in: Innovation (Cambridge (Mass.))
information resource reference: Toward equitable, transparent, and collaborative human mobility computing for smart cities. Innovation (Camb). 2024 Sep 09; 5(5):100672.
journal title abbreviation: Innovation (Camb)
publication date: 2024-07-02T00:00:00
year: 2024
type: Academic Article
type: Article
type: Document
type: Information Resource

Data-knowledge co-driven innovations in engineering and management.
PubMed Identifier: 39776847
author list: Xia Y, Chen XM, Sun S
published in: Patterns (New York, N.Y.)
information resource reference: Data-knowledge co-driven innovations in engineering and management. Patterns (N Y). 2024 Dec 13; 5(12):101114.
journal title abbreviation: Patterns (N Y)
publication date: 2024-12-13T00:00:00
year: 2024
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1717567
type: Authorship
author rank in publication: 2
linked author: Chen, Xiqun
linked information resource: Data-knowledge co-driven innovations in engineering and management.

Professor of Neurology
is primary position: true
position in department: Neurology
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sort order: 1
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HR job title: Professor of Neurology
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Authorship 1834126
type: Authorship
author rank in publication: 4
linked author: Chen, Xiqun
linked information resource: Integrating large language models and affective computing for human-machine symbiosis in intelligent driving.

Authorship 1845032
type: Authorship
author rank in publication: 4
linked author: Chen, Xiqun
linked information resource: Climate policy uncertainty and corporate carbon performance: Evidence from transportation enterprises.

Climate policy uncertainty and corporate carbon performance: Evidence from transportation enterprises.
PubMed Identifier: 40577863
author list: Zhao L, Liu Z, Xie C, Chen XM
published in: Journal of environmental management
information resource reference: Climate policy uncertainty and corporate carbon performance: Evidence from transportation enterprises. J Environ Manage. 2025 Aug; 390:126346.
journal title abbreviation: J Environ Manage
publication date: 2025-06-26T00:00:00
year: 2025
type: Academic Article
type: Article
type: Document
type: Information Resource

Integrating large language models and affective computing for human-machine symbiosis in intelligent driving.
PubMed Identifier: 41626549
author list: Dong Z, Chen C, Liao C, Chen XM
published in: Innovation (Cambridge (Mass.))
information resource reference: Integrating large language models and affective computing for human-machine symbiosis in intelligent driving. Innovation (Camb). 2025 Dec 01; 6(12):101014.
journal title abbreviation: Innovation (Camb)
publication date: 2025-06-30T00:00:00
year: 2025
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 341911
type: Authorship
author rank in publication: 1
linked author: Chen, Xiqun
linked information resource: Activation of tyrosine hydroxylase mRNA translation by cAMP in midbrain dopaminergic neurons.

Authorship 341638
type: Authorship
author rank in publication: 2
linked author: Chen, Xiqun
linked information resource: Dopaminergic pathway reconstruction by Akt/Rheb-induced axon regeneration.

Professor of Epidemiology and Nutrition
is primary position: true
position in department: Nutrition
position in division: https://connects.catalyst.harvard.edu/Profiles/profile/1229413
sort order: 1
type: Position
HR job title: Professor of Epidemiology and Nutrition
position in organization: Harvard T.H. Chan School of Public Health

Choi, Hyon
eCommons Login: HKC2
first name: Hyon
last name: Choi
full name: Hyon K. Choi, M.D.
has faculty rank: Full Professor
Person ID: 22691
person in primary position: Professor of Medicine
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preferred title: Professor of Medicine

Authorship 567886
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author rank in publication: 1
linked author: Chen, Xiqun
linked information resource: Urate in Parkinson's disease: more than a biomarker?

Emergency Medicine
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type: Organization

Authorship 408928
type: Authorship
author rank in publication: 1
linked author: Chen, Xiqun
linked information resource: Disrupted and transgenic urate oxidase alter urate and dopaminergic neurodegeneration.

Authorship 487078
type: Authorship
author rank in publication: 2
linked author: Chen, Xiqun
linked information resource: Chronic nicotine treatment leads to induction of tyrosine hydroxylase in locus ceruleus neurons: the role of transcriptional activation.

Authorship 341978
type: Authorship
author rank in publication: 3
linked author: Chen, Xiqun
linked information resource: Post-transcriptional regulation of tyrosine hydroxylase expression in adrenal medulla and brain.

Authorship 57272
type: Authorship
author rank in publication: 2
linked author: Chen, Xiqun
linked information resource: Urate: a novel biomarker of Parkinson's disease risk, diagnosis and prognosis.

Authorship 412120
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author rank in publication: 2
linked author: Chen, Xiqun
linked information resource: Evidence for regulation of tyrosine hydroxylase mRNA translation by stress in rat adrenal medulla.

Assistant Professor
sort order: 2
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Associate Professor
sort order: 1
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Full Professor
sort order: 0
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Authorship 34008
type: Authorship
author rank in publication: 1
linked author: Chen, Xiqun
linked information resource: Antiapoptotic and trophic effects of dominant-negative forms of dual leucine zipper kinase in dopamine neurons of the substantia nigra in vivo.

Urate in Parkinson's disease: more than a biomarker?
PubMed Identifier: 22580741
author list: Chen X, Wu G, Schwarzschild MA
published in: Current neurology and neuroscience reports
information resource reference: Urate in Parkinson's disease: more than a biomarker? Curr Neurol Neurosci Rep. 2012 Aug; 12(4):367-75.
journal title abbreviation: Curr Neurol Neurosci Rep
publication date: 2012-08-01T00:00:00
year: 2012
type: Academic Article
type: Article
type: Document
type: Information Resource

Post-transcriptional regulation of tyrosine hydroxylase expression in adrenal medulla and brain.
PubMed Identifier: 19120116
author list: Tank AW, Xu L, Chen X, Radcliffe P, Sterling CR
published in: Annals of the New York Academy of Sciences
information resource reference: Post-transcriptional regulation of tyrosine hydroxylase expression in adrenal medulla and brain. Ann N Y Acad Sci. 2008 Dec; 1148:238-48.
journal title abbreviation: Ann N Y Acad Sci
publication date: 2008-12-01T00:00:00
year: 2008
type: Academic Article
type: Article
type: Document
type: Information Resource

Chronic nicotine treatment leads to induction of tyrosine hydroxylase in locus ceruleus neurons: the role of transcriptional activation.
PubMed Identifier: 15258258
author list: Sun B, Chen X, Xu L, Sterling C, Tank AW
published in: Molecular pharmacology
information resource reference: Chronic nicotine treatment leads to induction of tyrosine hydroxylase in locus ceruleus neurons: the role of transcriptional activation. Mol Pharmacol. 2004 Oct; 66(4):1011-21.
journal title abbreviation: Mol Pharmacol
publication date: 2004-07-16T00:00:00
year: 2004
type: Academic Article
type: Article
type: Document
type: Information Resource

Activation of tyrosine hydroxylase mRNA translation by cAMP in midbrain dopaminergic neurons.
PubMed Identifier: 18349104
author list: Chen X, Xu L, Radcliffe P, Sun B, Tank AW
published in: Molecular pharmacology
information resource reference: Activation of tyrosine hydroxylase mRNA translation by cAMP in midbrain dopaminergic neurons. Mol Pharmacol. 2008 Jun; 73(6):1816-28.
journal title abbreviation: Mol Pharmacol
publication date: 2008-03-18T00:00:00
year: 2008
type: Academic Article
type: Article
type: Document
type: Information Resource

114 16th Street
type: Address
address line 1: Massachusetts General Hospital
address line 2: Mind - Rm 3003
address line 3: 114 16th Street
city: Charlestown
postal code: 02129
state or province: MA

Evidence for regulation of tyrosine hydroxylase mRNA translation by stress in rat adrenal medulla.
PubMed Identifier: 17543899
author list: Xu L, Chen X, Sun B, Sterling C, Tank AW
published in: Brain research
information resource reference: Evidence for regulation of tyrosine hydroxylase mRNA translation by stress in rat adrenal medulla. Brain Res. 2007 Jul 16; 1158:1-10.
journal title abbreviation: Brain Res
publication date: 2007-05-10T00:00:00
year: 2007
type: Academic Article
type: Article
type: Document
type: Information Resource

Antiapoptotic and trophic effects of dominant-negative forms of dual leucine zipper kinase in dopamine neurons of the substantia nigra in vivo.
PubMed Identifier: 18199767
author list: Chen X, Rzhetskaya M, Kareva T, Bland R, During MJ, Tank AW, Kholodilov N, Burke RE
published in: The Journal of neuroscience : the official journal of the Society for Neuroscience
information resource reference: Antiapoptotic and trophic effects of dominant-negative forms of dual leucine zipper kinase in dopamine neurons of the substantia nigra in vivo. J Neurosci. 2008 Jan 16; 28(3):672-80.
journal title abbreviation: J Neurosci
publication date: 2008-01-16T00:00:00
year: 2008
type: Academic Article
type: Article
type: Document
type: Information Resource

Urate: a novel biomarker of Parkinson's disease risk, diagnosis and prognosis.
PubMed Identifier: 20945982
author list: Cipriani S, Chen X, Schwarzschild MA
published in: Biomarkers in medicine
information resource reference: Urate: a novel biomarker of Parkinson's disease risk, diagnosis and prognosis. Biomark Med. 2010 Oct; 4(5):701-12.
journal title abbreviation: Biomark Med
publication date: 2010-10-01T00:00:00
year: 2010
type: Academic Article
type: Article
type: Document
type: Information Resource

Disrupted and transgenic urate oxidase alter urate and dopaminergic neurodegeneration.
PubMed Identifier: 23248282
author list: Chen X, Burdett TC, Desjardins CA, Logan R, Cipriani S, Xu Y, Schwarzschild MA
published in: Proceedings of the National Academy of Sciences of the United States of America
information resource reference: Disrupted and transgenic urate oxidase alter urate and dopaminergic neurodegeneration. Proc Natl Acad Sci U S A. 2013 Jan 02; 110(1):300-5.
journal title abbreviation: Proc Natl Acad Sci U S A
publication date: 2012-12-17T00:00:00
year: 2012
type: Academic Article
type: Article
type: Document
type: Information Resource

Dopaminergic pathway reconstruction by Akt/Rheb-induced axon regeneration.
PubMed Identifier: 21437936
author list: Kim SR, Chen X, Oo TF, Kareva T, Yarygina O, Wang C, During M, Kholodilov N, Burke RE
published in: Annals of neurology
information resource reference: Dopaminergic pathway reconstruction by Akt/Rheb-induced axon regeneration. Ann Neurol. 2011 Jul; 70(1):110-20.
journal title abbreviation: Ann Neurol
publication date: 2011-03-17T00:00:00
year: 2011
type: Academic Article
type: Article
type: Document
type: Information Resource