Flier, Sarah
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full name: Sarah Nicole Flier, M.D.
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research areas: Inflammatory Bowel Diseases
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research areas: Pancreatitis
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mailing address: 330 Brookline Ave
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Altered function of insulin receptor substrate-1-deficient mouse islets and cultured beta-cell lines.
PubMed Identifier: 10606633
author list: Kulkarni RN, Winnay JN, Daniels M, Brüning JC, Flier SN, Hanahan D, Kahn CR
published in: The Journal of clinical investigation
information resource reference: Altered function of insulin receptor substrate-1-deficient mouse islets and cultured beta-cell lines. J Clin Invest. 1999 Dec; 104(12):R69-75.
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Authorship 1047543
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linked information resource: Emergency department utilisation for inflammatory bowel disease in the United States from 2006 to 2014.

Emergency department utilisation for inflammatory bowel disease in the United States from 2006 to 2014.
PubMed Identifier: 29411411
author list: Ballou S, Hirsch W, Singh P, Rangan V, Nee J, Iturrino J, Sommers T, Zubiago J, Sengupta N, Bollom A, Jones M, Moss AC, Flier SN, Cheifetz AS, Lembo A
published in: Alimentary pharmacology & therapeutics
information resource reference: Emergency department utilisation for inflammatory bowel disease in the United States from 2006 to 2014. Aliment Pharmacol Ther. 2018 Apr; 47(7):913-921.
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Anti-melanin-concentrating hormone treatment attenuates chronic experimental colitis and fibrosis.
PubMed Identifier: 23538494
author list: Ziogas DC, Gras-Miralles B, Mustafa S, Geiger BM, Najarian RM, Nagel JM, Flier SN, Popov Y, Tseng YH, Kokkotou E
published in: American journal of physiology. Gastrointestinal and liver physiology
information resource reference: Anti-melanin-concentrating hormone treatment attenuates chronic experimental colitis and fibrosis. Am J Physiol Gastrointest Liver Physiol. 2013 May 15; 304(10):G876-84.
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Amat, Maelys
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Contribution of epithelial plasticity to renal transplantation-associated fibrosis.
PubMed Identifier: 21095454
author list: Hertig A, Flier SN, Kalluri R
published in: Transplantation proceedings
information resource reference: Contribution of epithelial plasticity to renal transplantation-associated fibrosis. Transplant Proc. 2010 Nov; 42(9 Suppl):S7-12.
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Fibroblast Growth Factors
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Feuerstein, Joseph
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Xavier, Ramnik
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Ananthakrishnan, Ashwin
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Fishman, Laurie
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Cheney, Catherine
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Sheth, Sunil
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Cheifetz, Adam
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Freedman, Steven
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Keates, Andrew
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Authorship 1281649
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author rank in publication: 6
linked author: Flier, Sarah
linked information resource: Clinical Impact of Corrections to Infliximab and Adalimumab Monitoring Results with the Homogeneous Mobility Shift Assay.

Clinical Impact of Corrections to Infliximab and Adalimumab Monitoring Results with the Homogeneous Mobility Shift Assay.
PubMed Identifier: 32887317
author list: Papamichael K, Thomas VJ, Banty A, Clarke WT, Germansky KA, Flier SN, Feuerstein JD, Melmed GY, Cheifetz AS
published in: Journal of clinical medicine
information resource reference: Clinical Impact of Corrections to Infliximab and Adalimumab Monitoring Results with the Homogeneous Mobility Shift Assay. J Clin Med. 2020 Sep 02; 9(9).
journal title abbreviation: J Clin Med
publication date: 2020-09-02T00:00:00
year: 2020
type: Academic Article
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Authorship 1322283
type: Authorship
author rank in publication: 3
linked author: Flier, Sarah
linked information resource: Patients With Low Drug Levels or Antibodies to a Prior Anti-Tumor Necrosis Factor Are More Likely to Develop Antibodies to a Subsequent Anti-Tumor Necrosis Factor.

Patients With Low Drug Levels or Antibodies to a Prior Anti-Tumor Necrosis Factor Are More Likely to Develop Antibodies to a Subsequent Anti-Tumor Necrosis Factor.
PubMed Identifier: 33421628
author list: Vande Casteele N, Abreu MT, Flier S, Papamichael K, Rieder F, Silverberg MS, Khanna R, Okada L, Yang L, Jain A, Cheifetz AS
published in: Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association
information resource reference: Patients With Low Drug Levels or Antibodies to a Prior Anti-Tumor Necrosis Factor Are More Likely to Develop Antibodies to a Subsequent Anti-Tumor Necrosis Factor. Clin Gastroenterol Hepatol. 2022 02; 20(2):465-467.e2.
journal title abbreviation: Clin Gastroenterol Hepatol
publication date: 2021-01-06T00:00:00
year: 2021
type: Academic Article
type: Article
type: Document
type: Information Resource

Patient Perspective on Safety of Elective Gastrointestinal Endoscopy During the COVID-19 Pandemic.
PubMed Identifier: 34007972
author list: Taneja V, El-Dallal M, Bilal M, Flier SN, Sheth SG, Ballou SK, Berzin TM, Pleskow DK, Feuerstein JD, Sawhney MS
published in: Techniques and innovations in gastrointestinal endoscopy
information resource reference: Patient Perspective on Safety of Elective Gastrointestinal Endoscopy During the COVID-19 Pandemic. Tech Innov Gastrointest Endosc. 2021; 23(3):234-243.
journal title abbreviation: Tech Innov Gastrointest Endosc
publication date: 2021-05-14T00:00:00
year: 2021
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1354155
type: Authorship
author rank in publication: 4
linked author: Flier, Sarah
linked information resource: Patient Perspective on Safety of Elective Gastrointestinal Endoscopy During the COVID-19 Pandemic.

Authorship 1605485
type: Authorship
author rank in publication: 4
linked author: Flier, Sarah
linked information resource: Completion Rates and Timeliness of Diagnostic Colonoscopies for Rectal Bleeding in Primary Care.

Completion Rates and Timeliness of Diagnostic Colonoscopies for Rectal Bleeding in Primary Care.
PubMed Identifier: 37940753
author list: Campbell KA, Sternberg SB, Benneyan J, Flier SN, Amat M, Salant T, Nambara K, Fernandez L, Feuerstein J, Shafiq U, Phillips RS, Aronson MD, Schiff GD
published in: Journal of general internal medicine
information resource reference: Completion Rates and Timeliness of Diagnostic Colonoscopies for Rectal Bleeding in Primary Care. J Gen Intern Med. 2024 05; 39(6):985-991.
journal title abbreviation: J Gen Intern Med
publication date: 2023-11-08T00:00:00
year: 2023
type: Academic Article
type: Article
type: Document
type: Information Resource

Associate Professor of Medicine
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Assistant Professor of Medicine, Part-time
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Assistant Professor of Medicine
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position in organization: Beth Israel Deaconess Medical Center

Assistant Professor of Medicine
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position in organization: Beth Israel Deaconess Medical Center

Associate Professor of Medicine
is primary position: true
position in department: Medicine
position in division: Gastroenterology
sort order: 1
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HR job title: Associate Professor of Medicine
position in organization: Massachusetts General Hospital

Kurt J. Isselbacher Professor of Medicine in the Field of Gastroenterology
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position in department: Medicine
position in division: Gastroenterology
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HR job title: Kurt J. Isselbacher Professor of Medicine in the Field of Gastroenterology
position in organization: Massachusetts General Hospital

Authorship 666846
type: Authorship
author rank in publication: 7
linked author: Flier, Sarah
linked information resource: Anti-melanin-concentrating hormone treatment attenuates chronic experimental colitis and fibrosis.

Authorship 216619
type: Authorship
author rank in publication: 3
linked author: Flier, Sarah
linked information resource: Leptin accelerates the onset of puberty in normal female mice.

Professor of Medicine
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position in department: Medicine
position in division: Gastroenterology
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position in organization: Beth Israel Deaconess Medical Center

Professor of Medicine
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position in department: Medicine
position in division: Gastroenterology
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position in organization: Beth Israel Deaconess Medical Center

Assistant Professor of Medicine, Part-time
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Professor of Clinical Medicine
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position in organization: Beth Israel Deaconess Medical Center

Authorship 1830017
type: Authorship
author rank in publication: 5
linked author: Flier, Sarah
linked information resource: Evaluation of a Telephone Outreach Intervention on Colonoscopy Completion Rates for Patients With Rectal Bleeding.

Evaluation of a Telephone Outreach Intervention on Colonoscopy Completion Rates for Patients With Rectal Bleeding.
PubMed Identifier: 41489935
author list: Amat M, Huang D, Ricci D, Benneyan J, Flier S, Shanmugam H, Sternberg S, Pollack A, Fernandez L, Salant T, Aronson M, Schiff G, Phillips R
published in: Journal for healthcare quality : official publication of the National Association for Healthcare Quality
information resource reference: Evaluation of a Telephone Outreach Intervention on Colonoscopy Completion Rates for Patients With Rectal Bleeding. J Healthc Qual. 2026 Jan-Mar 01; 48(1).
journal title abbreviation: J Healthc Qual
publication date: 2026-01-02T00:00:00
year: 2026
type: Academic Article
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type: Document
type: Information Resource

Gastroenterology & Nutrition
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Associate Professor of Pediatrics
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position in organization: Boston Children's Hospital

A rare case series of concomitant inflammatory bowel disease, sporadic adenomas, and serrated polyposis syndrome.
PubMed Identifier: 25047878
author list: Feuerstein JD, Flier SN, Yee EU, Pleskow D, Cheifetz AS
published in: Journal of Crohn's & colitis
information resource reference: A rare case series of concomitant inflammatory bowel disease, sporadic adenomas, and serrated polyposis syndrome. J Crohns Colitis. 2014 Dec; 8(12):1735-9.
journal title abbreviation: J Crohns Colitis
publication date: 2014-07-18T00:00:00
year: 2014
type: Academic Article
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Authorship 772056
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linked information resource: A rare case series of concomitant inflammatory bowel disease, sporadic adenomas, and serrated polyposis syndrome.

Authorship 333345
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linked information resource: Is functional dyspepsia of particular concern in women? A review of gender differences in epidemiology, pathophysiologic mechanisms, clinical presentation, and management.

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linked author: Flier, Sarah
linked information resource: Altered function of insulin receptor substrate-1-deficient mouse islets and cultured beta-cell lines.

Authorship 57904
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linked information resource: Evidence for a circulating islet cell growth factor in insulin-resistant states.

Authorship 72596
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linked information resource: Contribution of epithelial plasticity to renal transplantation-associated fibrosis.

Papamichail, Konstantinos
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linked information resource: A case confirming the progressive stages of pyomyositis.

Authorship 502247
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linked author: Flier, Sarah
linked information resource: Identification of epithelial to mesenchymal transition as a novel source of fibroblasts in intestinal fibrosis.

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Epithelial to Mesenchymal Transition and Fibrosis in Inflammatory Bowel Disease
end date: 2016-12-31
principal investigator name: FLIER, SARAH NICOLE
start date: 2011-05-01
type: Grant
sponsor award id: K08DK087901

Principal Investigator
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researcher role of: Flier, Sarah
contributes to: Epithelial to Mesenchymal Transition and Fibrosis in Inflammatory Bowel Disease

Authorship 922426
type: Authorship
author rank in publication: 5
linked author: Flier, Sarah
linked information resource: Are Expectations Too High for Transitioning Adolescents With Inflammatory Bowel Disease? Examining Adult Medication Knowledge and Self-Management Skills.

Are Expectations Too High for Transitioning Adolescents With Inflammatory Bowel Disease? Examining Adult Medication Knowledge and Self-Management Skills.
PubMed Identifier: 27280748
author list: Fishman LN, Mitchell PD, Lakin PR, Masciarelli L, Flier SN
published in: Journal of pediatric gastroenterology and nutrition
information resource reference: Are Expectations Too High for Transitioning Adolescents With Inflammatory Bowel Disease? Examining Adult Medication Knowledge and Self-Management Skills. J Pediatr Gastroenterol Nutr. 2016 11; 63(5):494-499.
journal title abbreviation: J Pediatr Gastroenterol Nutr
publication date: 2016-11-01T00:00:00
year: 2016
type: Academic Article
type: Article
type: Document
type: Information Resource

Elevated Serum Fibroblast Growth Factor 21 in Humans with Acute Pancreatitis.
PubMed Identifier: 27832059
author list: Shenoy VK, Beaver KM, Fisher FM, Singhal G, Dushay JR, Maratos-Flier E, Flier SN
published in: PloS one
information resource reference: Elevated Serum Fibroblast Growth Factor 21 in Humans with Acute Pancreatitis. PLoS One. 2016; 11(11):e0164351.
journal title abbreviation: PLoS One
publication date: 2016-11-10T00:00:00
year: 2016
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 934109
type: Authorship
author rank in publication: 7
linked author: Flier, Sarah
linked information resource: Elevated Serum Fibroblast Growth Factor 21 in Humans with Acute Pancreatitis.

Authorship 954509
type: Authorship
linked author: Flier, Sarah
linked information resource: How to Create an Unfunded Teaching Fellowship During the Gastroenterology Fellowship That Positively Impacts Subsequent Teaching Activities and Career Path.

How to Create an Unfunded Teaching Fellowship During the Gastroenterology Fellowship That Positively Impacts Subsequent Teaching Activities and Career Path.
PubMed Identifier: 28153607
author list: Shields HM
published in: Gastroenterology
information resource reference: How to Create an Unfunded Teaching Fellowship During the Gastroenterology Fellowship That Positively Impacts Subsequent Teaching Activities and Career Path. Gastroenterology. 2017 03; 152(4):689-692.
journal title abbreviation: Gastroenterology
publication date: 2017-01-30T00:00:00
year: 2017
type: Academic Article
type: Article
type: Document
type: Information Resource

Evidence for a circulating islet cell growth factor in insulin-resistant states.
PubMed Identifier: 11404474
author list: Flier SN, Kulkarni RN, Kahn CR
published in: Proceedings of the National Academy of Sciences of the United States of America
information resource reference: Evidence for a circulating islet cell growth factor in insulin-resistant states. Proc Natl Acad Sci U S A. 2001 Jun 19; 98(13):7475-80.
journal title abbreviation: Proc Natl Acad Sci U S A
publication date: 2001-06-12T00:00:00
year: 2001
type: Academic Article
type: Article
type: Document
type: Information Resource

Is functional dyspepsia of particular concern in women? A review of gender differences in epidemiology, pathophysiologic mechanisms, clinical presentation, and management.
PubMed Identifier: 17177870
author list: Flier SN, Rose S
published in: The American journal of gastroenterology
information resource reference: Is functional dyspepsia of particular concern in women? A review of gender differences in epidemiology, pathophysiologic mechanisms, clinical presentation, and management. Am J Gastroenterol. 2006 Dec; 101(12 Suppl):S644-53.
journal title abbreviation: Am J Gastroenterol
publication date: 2006-12-01T00:00:00
year: 2006
type: Academic Article
type: Article
type: Document
type: Information Resource

Leptin accelerates the onset of puberty in normal female mice.
PubMed Identifier: 9022071
author list: Ahima RS, Dushay J, Flier SN, Prabakaran D, Flier JS
published in: The Journal of clinical investigation
information resource reference: Leptin accelerates the onset of puberty in normal female mice. J Clin Invest. 1997 Feb 01; 99(3):391-5.
journal title abbreviation: J Clin Invest
publication date: 1997-02-01T00:00:00
year: 1997
type: Academic Article
type: Article
type: Document
type: Information Resource

Identification of epithelial to mesenchymal transition as a novel source of fibroblasts in intestinal fibrosis.
PubMed Identifier: 20363741
author list: Flier SN, Tanjore H, Kokkotou EG, Sugimoto H, Zeisberg M, Kalluri R
published in: The Journal of biological chemistry
information resource reference: Identification of epithelial to mesenchymal transition as a novel source of fibroblasts in intestinal fibrosis. J Biol Chem. 2010 Jun 25; 285(26):20202-12.
journal title abbreviation: J Biol Chem
publication date: 2010-04-02T00:00:00
year: 2010
type: Academic Article
type: Article
type: Document
type: Information Resource

A case confirming the progressive stages of pyomyositis.
PubMed Identifier: 14577088
author list: Flier S, Dolgin SE, Saphir RL, Shlasko E, Midulla P
published in: Journal of pediatric surgery
information resource reference: A case confirming the progressive stages of pyomyositis. J Pediatr Surg. 2003 Oct; 38(10):1551-3.
journal title abbreviation: J Pediatr Surg
publication date: 2003-10-01T00:00:00
year: 2003
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1026309
type: Authorship
author rank in publication: 3
linked author: Flier, Sarah
linked information resource: Volunteer patients and small groups contribute to abdominal examination's success.

Volunteer patients and small groups contribute to abdominal examination's success.
PubMed Identifier: 29138611
author list: Shields HM, Fernandez-Becker NQ, Flier SN, Vaughn BP, Tukey MH, Pelletier SR, Horst DA
published in: Advances in medical education and practice
information resource reference: Volunteer patients and small groups contribute to abdominal examination's success. Adv Med Educ Pract. 2017; 8:721-729.
journal title abbreviation: Adv Med Educ Pract
publication date: 2017-11-01T00:00:00
year: 2017
type: Academic Article
type: Article
type: Document
type: Information Resource

330 Brookline Ave
type: Address
address line 1: Beth Israel Deaconess Medical Center
address line 2: GI Division - Rabb 420
address line 3: 330 Brookline Ave
city: Boston
postal code: 02215
state or province: MA

Authorship 1031313
type: Authorship
author rank in publication: 3
linked author: Flier, Sarah
linked information resource: Intestinal, but not hepatic, ChREBP is required for fructose tolerance.

Intestinal, but not hepatic, ChREBP is required for fructose tolerance.
PubMed Identifier: 29263303
author list: Kim M, Astapova II, Flier SN, Hannou SA, Doridot L, Sargsyan A, Kou HH, Fowler AJ, Liang G, Herman MA
published in: JCI insight
information resource reference: Intestinal, but not hepatic, ChREBP is required for fructose tolerance. JCI Insight. 2017 12 21; 2(24).
journal title abbreviation: JCI Insight
publication date: 2017-12-21T00:00:00
year: 2017
type: Academic Article
type: Article
type: Document
type: Information Resource