Maurice Edmond Mueller Professor of Orthopedic Surgery
Christov M, Clark AR, Corbin B, Hakroush S, Rhee EP, Saito H, Brooks D, Hesse E, Bouxsein M, Galjart N, Jung JY, Mundel P, Jüppner H, Weins A, Greka A
Inducible podocyte-specific deletion of CTCF drives progressive kidney disease and bone abnormalities. JCI Insight. 2018 02 22; 3(4).
Inducible podocyte-specific deletion of CTCF drives progressive kidney disease and bone abnormalities.
van Dongen LH, Kiel DP, Soedamah-Muthu SS, Bouxsein ML, Hannan MT, Sahni S
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research
Higher Dairy Food Intake Is Associated With Higher Spine Quantitative Computed Tomography (QCT) Bone Measures in the Framingham Study for Men But Not Women. J Bone Miner Res. 2018 07; 33(7):1283-1290.
Higher Dairy Food Intake Is Associated With Higher Spine Quantitative Computed Tomography (QCT) Bone Measures in the Framingham Study for Men But Not Women.
Quantitative ultrasound does not reflect mechanically induced damage in human cancellous bone. J Bone Miner Res. 2000 Dec; 15(12):2467-72.
Quantitative ultrasound does not reflect mechanically induced damage in human cancellous bone.
Turner CH, Hsieh YF, Müller R, Bouxsein ML, Rosen CJ, McCrann ME, Donahue LR, Beamer WG
Variation in bone biomechanical properties, microstructure, and density in BXH recombinant inbred mice. J Bone Miner Res. 2001 Feb; 16(2):206-13.
Variation in bone biomechanical properties, microstructure, and density in BXH recombinant inbred mice.
Johannesdottir F, Allaire B, Anderson DE, Samelson EJ, Kiel DP, Bouxsein ML
Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA
Population-based study of age- and sex-related differences in muscle density and size in thoracic and lumbar spine: the Framingham study. Osteoporos Int. 2018 Jul; 29(7):1569-1580.
Population-based study of age- and sex-related differences in muscle density and size in thoracic and lumbar spine: the Framingham study.
Mortreux M, Nagy JA, Ko FC, Bouxsein ML, Rutkove SB
Journal of applied physiology (Bethesda, Md. : 1985)
A novel partial gravity ground-based analog for rats via quadrupedal unloading. J Appl Physiol (1985). 2018 07 01; 125(1):175-182.
A novel partial gravity ground-based analog for rats via quadrupedal unloading.
Ko FC, Li J, Brooks DJ, Rutkove SB, Bouxsein ML
Amyotrophic lateral sclerosis & frontotemporal degeneration
Structural and functional properties of bone are compromised in amyotrophic lateral sclerosis mice. Amyotroph Lateral Scler Frontotemporal Degener. 2018 08; 19(5-6):457-462.
Amyotroph Lateral Scler Frontotemporal Degener
Structural and functional properties of bone are compromised in amyotrophic lateral sclerosis mice.
Rosen CJ, Ackert-Bicknell CL, Adamo ML, Shultz KL, Rubin J, Donahue LR, Horton LG, Delahunty KM, Beamer WG, Sipos J, Clemmons D, Nelson T, Bouxsein ML, Horowitz M
Congenic mice with low serum IGF-I have increased body fat, reduced bone mineral density, and an altered osteoblast differentiation program. Bone. 2004 Nov; 35(5):1046-58.
Congenic mice with low serum IGF-I have increased body fat, reduced bone mineral density, and an altered osteoblast differentiation program.
Pierroz DD, Bouxsein ML, Rizzoli R, Ferrari SL
Combined treatment with a beta-blocker and intermittent PTH improves bone mass and microarchitecture in ovariectomized mice. Bone. 2006 Aug; 39(2):260-7.
Combined treatment with a beta-blocker and intermittent PTH improves bone mass and microarchitecture in ovariectomized mice.
Bouxsein ML, Melton LJ, Riggs BL, Muller J, Atkinson EJ, Oberg AL, Robb RA, Camp JJ, Rouleau PA, McCollough CH, Khosla S
Age- and sex-specific differences in the factor of risk for vertebral fracture: a population-based study using QCT. J Bone Miner Res. 2006 Sep; 21(9):1475-82.
Age- and sex-specific differences in the factor of risk for vertebral fracture: a population-based study using QCT.
Rozental TD, Makhni EC, Day CS, Bouxsein ML
The Journal of bone and joint surgery. American volume
Improving evaluation and treatment for osteoporosis following distal radial fractures. A prospective randomized intervention. J Bone Joint Surg Am. 2008 May; 90(5):953-61.
Improving evaluation and treatment for osteoporosis following distal radial fractures. A prospective randomized intervention.
Iyer S, Christiansen BA, Roberts BJ, Valentine MJ, Manoharan RK, Bouxsein ML
A biomechanical model for estimating loads on thoracic and lumbar vertebrae. Clin Biomech (Bristol). 2010 Nov; 25(9):853-8.
A biomechanical model for estimating loads on thoracic and lumbar vertebrae.
Adams AL, Fischer H, Kopperdahl DL, Lee DC, Black DM, Bouxsein ML, Fatemi S, Khosla S, Orwoll ES, Siris ES, Keaveny TM
Osteoporosis and Hip Fracture Risk From Routine Computed Tomography Scans: The Fracture, Osteoporosis, and CT Utilization Study (FOCUS). J Bone Miner Res. 2018 07; 33(7):1291-1301.
Osteoporosis and Hip Fracture Risk From Routine Computed Tomography Scans: The Fracture, Osteoporosis, and CT Utilization Study (FOCUS).
Seeherman HJ, Bouxsein M, Kim H, Li R, Li XJ, Aiolova M, Wozney JM
Recombinant human bone morphogenetic protein-2 delivered in an injectable calcium phosphate paste accelerates osteotomy-site healing in a nonhuman primate model. J Bone Joint Surg Am. 2004 Sep; 86(9):1961-72.
Recombinant human bone morphogenetic protein-2 delivered in an injectable calcium phosphate paste accelerates osteotomy-site healing in a nonhuman primate model.
Holmen SL, Zylstra CR, Mukherjee A, Sigler RE, Faugere MC, Bouxsein ML, Deng L, Clemens TL, Williams BO
Essential role of beta-catenin in postnatal bone acquisition. J Biol Chem. 2005 Jun 03; 280(22):21162-8.
Essential role of beta-catenin in postnatal bone acquisition.
Davey RA, Turner AG, McManus JF, Chiu WS, Tjahyono F, Moore AJ, Atkins GJ, Anderson PH, Ma C, Glatt V, MacLean HE, Vincent C, Bouxsein M, Morris HA, Findlay DM, Zajac JD
Calcitonin receptor plays a physiological role to protect against hypercalcemia in mice. J Bone Miner Res. 2008 Aug; 23(8):1182-93.
Calcitonin receptor plays a physiological role to protect against hypercalcemia in mice.
Jarraya M, Guermazi A, Lorbergs AL, Brochin E, Kiel DP, Bouxsein ML, Cupples LA, Samelson EJ
The spine journal : official journal of the North American Spine Society
A longitudinal study of disc height narrowing and facet joint osteoarthritis at the thoracic and lumbar spine, evaluated by computed tomography: the Framingham Study. Spine J. 2018 11; 18(11):2065-2073.
A longitudinal study of disc height narrowing and facet joint osteoarthritis at the thoracic and lumbar spine, evaluated by computed tomography: the Framingham Study.
Lorbergs AL, Allaire BT, Yang L, Kiel DP, Cupples LA, Jarraya M, Guermazi A, Travison TG, Bouxsein ML, Anderson DE, Samelson EJ
The journals of gerontology. Series A, Biological sciences and medical sciences
A Longitudinal Study of Trunk Muscle Properties and Severity of Thoracic Kyphosis in Women and Men: The Framingham Study. J Gerontol A Biol Sci Med Sci. 2019 02 15; 74(3):420-427.
A Longitudinal Study of Trunk Muscle Properties and Severity of Thoracic Kyphosis in Women and Men: The Framingham Study.
Dufour AB, Roberts B, Broe KE, Kiel DP, Bouxsein ML, Hannan MT
The factor-of-risk biomechanical approach predicts hip fracture in men and women: the Framingham Study. Osteoporos Int. 2012 Feb; 23(2):513-20.
The factor-of-risk biomechanical approach predicts hip fracture in men and women: the Framingham Study.
Liu CT, Karasik D, Zhou Y, Hsu YH, Genant HK, Broe KE, Lang TF, Samelson EJ, Demissie S, Bouxsein ML, Cupples LA, Kiel DP
Heritability of prevalent vertebral fracture and volumetric bone mineral density and geometry at the lumbar spine in three generations of the Framingham study. J Bone Miner Res. 2012 Apr; 27(4):954-8.
Heritability of prevalent vertebral fracture and volumetric bone mineral density and geometry at the lumbar spine in three generations of the Framingham study.
Braun TP, Orwoll B, Zhu X, Levasseur PR, Szumowski M, Nguyen ML, Bouxsein ML, Klein RF, Marks DL
Regulation of lean mass, bone mass, and exercise tolerance by the central melanocortin system. PLoS One. 2012; 7(7):e42183.
Regulation of lean mass, bone mass, and exercise tolerance by the central melanocortin system.
Hughes JM, Gaffney-Stomberg E, Guerriere KI, Taylor KM, Popp KL, Xu C, Unnikrishnan G, Staab JS, Matheny RW, McClung JP, Reifman J, Bouxsein ML
Changes in tibial bone microarchitecture in female recruits in response to 8?weeks of U.S. Army Basic Combat Training. Bone. 2018 08; 113:9-16.
Changes in tibial bone microarchitecture in female recruits in response to 8?weeks of U.S. Army Basic Combat Training.
Moro M, Hecker AT, Bouxsein ML, Myers ER
Failure load of thoracic vertebrae correlates with lumbar bone mineral density measured by DXA. Calcif Tissue Int. 1995 Mar; 56(3):206-9.
Failure load of thoracic vertebrae correlates with lumbar bone mineral density measured by DXA.
Rheumatic diseases clinics of North America
Overview of exercise and bone mass. Rheum Dis Clin North Am. 1994 Aug; 20(3):787-802.
Viguet-Carrin S, Farlay D, Bala Y, Munoz F, Bouxsein ML, Delmas PD
An in vitro model to test the contribution of advanced glycation end products to bone biomechanical properties. Bone. 2008 Jan; 42(1):139-49.
An in vitro model to test the contribution of advanced glycation end products to bone biomechanical properties.
Unnikrishnan G, Xu C, Popp KL, Hughes JM, Yuan A, Guerriere KI, Caksa S, Ackerman KE, Bouxsein ML, Reifman J
Regional variation of bone density, microarchitectural parameters, and elastic moduli in the ultradistal tibia of young black and white men and women. Bone. 2018 07; 112:194-201.
Regional variation of bone density, microarchitectural parameters, and elastic moduli in the ultradistal tibia of young black and white men and women.
Yang D, Singh R, Divieti P, Guo J, Bouxsein ML, Bringhurst FR
Contributions of parathyroid hormone (PTH)/PTH-related peptide receptor signaling pathways to the anabolic effect of PTH on bone. Bone. 2007 Jun; 40(6):1453-61.
Contributions of parathyroid hormone (PTH)/PTH-related peptide receptor signaling pathways to the anabolic effect of PTH on bone.
Tsiridis E, Morgan EF, Bancroft JM, Song M, Kain M, Gerstenfeld L, Einhorn TA, Bouxsein ML, Tornetta P
Journal of orthopaedic research : official publication of the Orthopaedic Research Society
Effects of OP-1 and PTH in a new experimental model for the study of metaphyseal bone healing. J Orthop Res. 2007 Sep; 25(9):1193-203.
Effects of OP-1 and PTH in a new experimental model for the study of metaphyseal bone healing.
Lotinun S, Pearsall RS, Davies MV, Marvell TH, Monnell TE, Ucran J, Fajardo RJ, Kumar R, Underwood KW, Seehra J, Bouxsein ML, Baron R
A soluble activin receptor Type IIA fusion protein (ACE-011) increases bone mass via a dual anabolic-antiresorptive effect in Cynomolgus monkeys. Bone. 2010 Apr; 46(4):1082-8.
A soluble activin receptor Type IIA fusion protein (ACE-011) increases bone mass via a dual anabolic-antiresorptive effect in Cynomolgus monkeys.
Devlin MJ, Cloutier AM, Thomas NA, Panus DA, Lotinun S, Pinz I, Baron R, Rosen CJ, Bouxsein ML
Caloric restriction leads to high marrow adiposity and low bone mass in growing mice. J Bone Miner Res. 2010 Sep; 25(9):2078-88.
Caloric restriction leads to high marrow adiposity and low bone mass in growing mice.
Kiel DP, Hannan MT, Barton BA, Bouxsein ML, Lang TF, Brown KM, Shane E, Magaziner J, Zimmerman S, Rubin CT
Insights from the conduct of a device trial in older persons: low magnitude mechanical stimulation for musculoskeletal health. Clin Trials. 2010 Aug; 7(4):354-67.
Insights from the conduct of a device trial in older persons: low magnitude mechanical stimulation for musculoskeletal health.
Johannesdottir F, Allaire B, Bouxsein ML
Fracture Prediction by Computed Tomography and Finite Element Analysis: Current and Future Perspectives. Curr Osteoporos Rep. 2018 08; 16(4):411-422.
Fracture Prediction by Computed Tomography and Finite Element Analysis: Current and Future Perspectives.
Influence of pre- and peri-natal nutrition on skeletal acquisition and maintenance. Bone. 2012 Feb; 50(2):444-51.
Influence of pre- and peri-natal nutrition on skeletal acquisition and maintenance.
Kim YM, Demissie S, Genant HK, Cheng X, Yu W, Samelson EJ, Kiel DP, Bouxsein ML
Identification of prevalent vertebral fractures using CT lateral scout views: a comparison of semi-automated quantitative vertebral morphometry and radiologist semi-quantitative grading. Osteoporos Int. 2012 Mar; 23(3):1007-16.
Identification of prevalent vertebral fractures using CT lateral scout views: a comparison of semi-automated quantitative vertebral morphometry and radiologist semi-quantitative grading.
Reply to the Letter to the Editor "Peripartum nutrition and adult bone health". Bone. 2012 Jul; 51(1):186.
Reply to the Letter to the Editor "Peripartum nutrition and adult bone health".
Karim L, Moulton J, Van Vliet M, Velie K, Robbins A, Malekipour F, Abdeen A, Ayres D, Bouxsein ML
Bone microarchitecture, biomechanical properties, and advanced glycation end-products in the proximal femur of adults with type 2 diabetes. Bone. 2018 09; 114:32-39.
Bone microarchitecture, biomechanical properties, and advanced glycation end-products in the proximal femur of adults with type 2 diabetes.
Liu CT, Sahni S, Xu H, McLean RR, Broe KE, Hannan MT, Boyd SK, Bouxsein ML, Kiel DP, Samelson EJ
Long-Term and Recent Weight Change Are Associated With Reduced Peripheral Bone Density, Deficits in Bone Microarchitecture, and Decreased Bone Strength: The Framingham Osteoporosis Study. J Bone Miner Res. 2018 10; 33(10):1851-1858.
Long-Term and Recent Weight Change Are Associated With Reduced Peripheral Bone Density, Deficits in Bone Microarchitecture, and Decreased Bone Strength: The Framingham Osteoporosis Study.
Christiansen BA, Kopperdahl DL, Kiel DP, Keaveny TM, Bouxsein ML
Mechanical contributions of the cortical and trabecular compartments contribute to differences in age-related changes in vertebral body strength in men and women assessed by QCT-based finite element analysis. J Bone Miner Res. 2011 May; 26(5):974-83.
Mechanical contributions of the cortical and trabecular compartments contribute to differences in age-related changes in vertebral body strength in men and women assessed by QCT-based finite element analysis.
Tingart MJ, Bouxsein ML, Zurakowski D, Warner JP, Apreleva M
Three-dimensional distribution of bone density in the proximal humerus. Calcif Tissue Int. 2003 Dec; 73(6):531-6.
Three-dimensional distribution of bone density in the proximal humerus.
Bouxsein ML, Uchiyama T, Rosen CJ, Shultz KL, Donahue LR, Turner CH, Sen S, Churchill GA, Müller R, Beamer WG
Mapping quantitative trait loci for vertebral trabecular bone volume fraction and microarchitecture in mice. J Bone Miner Res. 2004 Apr; 19(4):587-99.
Mapping quantitative trait loci for vertebral trabecular bone volume fraction and microarchitecture in mice.
Shultz KL, Donahue LR, Bouxsein ML, Baylink DJ, Rosen CJ, Beamer WG
Congenic strains of mice for verification and genetic decomposition of quantitative trait loci for femoral bone mineral density. J Bone Miner Res. 2003 Feb; 18(2):175-85.
Congenic strains of mice for verification and genetic decomposition of quantitative trait loci for femoral bone mineral density.
Devlin MJ, Robbins A, Cosman MN, Moursi CA, Cloutier AM, Louis L, Van Vliet M, Conlon C, Bouxsein ML
Differential effects of high fat diet and diet-induced obesity on skeletal acquisition in female C57BL/6J vs. FVB/NJ Mice. Bone Rep. 2018 Jun; 8:204-214.
Differential effects of high fat diet and diet-induced obesity on skeletal acquisition in female C57BL/6J vs. FVB/NJ Mice.
Johnston JD, Small CF, Bouxsein ML, Pichora DR
Mechanical properties of the scapholunate ligament correlate with bone mineral density measurements of the hand. J Orthop Res. 2004 Jul; 22(4):867-71.
Mechanical properties of the scapholunate ligament correlate with bone mineral density measurements of the hand.
Cortical stability of the femoral neck and hip fracture risk. Lancet. 2005 Oct 29-Nov 4; 366(9496):1523-4; author reply 1524-5.
Cortical stability of the femoral neck and hip fracture risk.
Black DM, Bouxsein ML, Palermo L, McGowan JA, Newitt DC, Rosen E, Majumdar S, Rosen CJ
The Journal of clinical endocrinology and metabolism
Randomized trial of once-weekly parathyroid hormone (1-84) on bone mineral density and remodeling. J Clin Endocrinol Metab. 2008 Jun; 93(6):2166-72.
Randomized trial of once-weekly parathyroid hormone (1-84) on bone mineral density and remodeling.
Okazaki M, Ferrandon S, Vilardaga JP, Bouxsein ML, Potts JT, Gardella TJ
Proceedings of the National Academy of Sciences of the United States of America
Prolonged signaling at the parathyroid hormone receptor by peptide ligands targeted to a specific receptor conformation. Proc Natl Acad Sci U S A. 2008 Oct 28; 105(43):16525-30.
Prolonged signaling at the parathyroid hormone receptor by peptide ligands targeted to a specific receptor conformation.
Guo J, Liu M, Yang D, Bouxsein ML, Saito H, Galvin RJ, Kuhstoss SA, Thomas CC, Schipani E, Baron R, Bringhurst FR, Kronenberg HM
Suppression of Wnt signaling by Dkk1 attenuates PTH-mediated stromal cell response and new bone formation. Cell Metab. 2010 Feb 03; 11(2):161-71.
Suppression of Wnt signaling by Dkk1 attenuates PTH-mediated stromal cell response and new bone formation.
Kawai M, Breggia AC, DeMambro VE, Shen X, Canalis E, Bouxsein ML, Beamer WG, Clemmons DR, Rosen CJ
The heparin-binding domain of IGFBP-2 has insulin-like growth factor binding-independent biologic activity in the growing skeleton. J Biol Chem. 2011 Apr 22; 286(16):14670-80.
The heparin-binding domain of IGFBP-2 has insulin-like growth factor binding-independent biologic activity in the growing skeleton.
Anderson DE, D'Agostino JM, Bruno AG, Manoharan RK, Bouxsein ML
Regressions for estimating muscle parameters in the thoracic and lumbar trunk for use in musculoskeletal modeling. J Biomech. 2012 Jan 03; 45(1):66-75.
Regressions for estimating muscle parameters in the thoracic and lumbar trunk for use in musculoskeletal modeling.
Spatz JM, Ellman R, Cloutier AM, Louis L, van Vliet M, Suva LJ, Dwyer D, Stolina M, Ke HZ, Bouxsein ML
Sclerostin antibody inhibits skeletal deterioration due to reduced mechanical loading. J Bone Miner Res. 2013 Apr; 28(4):865-74.
Sclerostin antibody inhibits skeletal deterioration due to reduced mechanical loading.
Brouwers JE, Ruchelsman M, Rietbergen Bv, Bouxsein ML
Determination of rat vertebral bone compressive fatigue properties in untreated intact rats and zoledronic-acid-treated, ovariectomized rats. Osteoporos Int. 2009 Aug; 20(8):1377-84.
Determination of rat vertebral bone compressive fatigue properties in untreated intact rats and zoledronic-acid-treated, ovariectomized rats.
Fritton JC, Emerton KB, Sun H, Kawashima Y, Mejia W, Wu Y, Rosen CJ, Panus D, Bouxsein M, Majeska RJ, Schaffler MB, Yakar S
Growth hormone protects against ovariectomy-induced bone loss in states of low circulating insulin-like growth factor (IGF-1). J Bone Miner Res. 2010 Feb; 25(2):235-46.
Growth hormone protects against ovariectomy-induced bone loss in states of low circulating insulin-like growth factor (IGF-1).
Brouwers JE, van Rietbergen B, Bouxsein ML
Influence of early and late zoledronic acid administration on vertebral structure and strength in ovariectomized rats. Calcif Tissue Int. 2008 Sep; 83(3):186-91.
Influence of early and late zoledronic acid administration on vertebral structure and strength in ovariectomized rats.
Shomento SH, Wan C, Cao X, Faugere MC, Bouxsein ML, Clemens TL, Riddle RC
Hypoxia-inducible factors 1alpha and 2alpha exert both distinct and overlapping functions in long bone development. J Cell Biochem. 2010 Jan 01; 109(1):196-204.
Hypoxia-inducible factors 1alpha and 2alpha exert both distinct and overlapping functions in long bone development.
Black DM, Abrahamsen B, Bouxsein ML, Einhorn T, Napoli N
Atypical Femur Fractures: Review of Epidemiology, Relationship to Bisphosphonates, Prevention, and Clinical Management. Endocr Rev. 2019 04 01; 40(2):333-368.
Atypical Femur Fractures: Review of Epidemiology, Relationship to Bisphosphonates, Prevention, and Clinical Management.
Grasemann C, Devlin MJ, Rzeczkowska PA, Herrmann R, Horsthemke B, Hauffa BP, Grynpas M, Alm C, Bouxsein ML, Palmert MR
Parental diabetes: the Akita mouse as a model of the effects of maternal and paternal hyperglycemia in wildtype offspring. PLoS One. 2012; 7(11):e50210.
Parental diabetes: the Akita mouse as a model of the effects of maternal and paternal hyperglycemia in wildtype offspring.
Lawson EA, Ackerman KE, Estella NM, Guereca G, Pierce L, Sluss PM, Bouxsein ML, Klibanski A, Misra M
Nocturnal oxytocin secretion is lower in amenorrheic athletes than nonathletes and associated with bone microarchitecture and finite element analysis parameters. Eur J Endocrinol. 2013 Mar; 168(3):457-64.
Nocturnal oxytocin secretion is lower in amenorrheic athletes than nonathletes and associated with bone microarchitecture and finite element analysis parameters.
Fajardo RJ, Desilva JM, Manoharan RK, Schmitz JE, Maclatchy LM, Bouxsein ML
Anatomical record (Hoboken, N.J. : 2007)
Lumbar vertebral body bone microstructural scaling in small to medium-sized strepsirhines. Anat Rec (Hoboken). 2013 Feb; 296(2):210-26.
Lumbar vertebral body bone microstructural scaling in small to medium-sized strepsirhines.
Devlin MJ, Grasemann C, Cloutier AM, Louis L, Alm C, Palmert MR, Bouxsein ML
Maternal perinatal diet induces developmental programming of bone architecture. J Endocrinol. 2013 Apr; 217(1):69-81.
Maternal perinatal diet induces developmental programming of bone architecture.
Baud'huin M, Solban N, Cornwall-Brady M, Sako D, Kawamoto Y, Liharska K, Lath D, Bouxsein ML, Underwood KW, Ucran J, Kumar R, Pobre E, Grinberg A, Seehra J, Canalis E, Pearsall RS, Croucher PI
A soluble bone morphogenetic protein type IA receptor increases bone mass and bone strength. Proc Natl Acad Sci U S A. 2012 Jul 24; 109(30):12207-12.
A soluble bone morphogenetic protein type IA receptor increases bone mass and bone strength.
Shimada M, Greer PA, McMahon AP, Bouxsein ML, Schipani E
In vivo targeted deletion of calpain small subunit, Capn4, in cells of the osteoblast lineage impairs cell proliferation, differentiation, and bone formation. J Biol Chem. 2008 Jul 25; 283(30):21002-10.
In vivo targeted deletion of calpain small subunit, Capn4, in cells of the osteoblast lineage impairs cell proliferation, differentiation, and bone formation.
Fajardo RJ, Cory E, Patel ND, Nazarian A, Laib A, Manoharan RK, Schmitz JE, DeSilva JM, MacLatchy LM, Snyder BD, Bouxsein ML
Specimen size and porosity can introduce error into microCT-based tissue mineral density measurements. Bone. 2009 Jan; 44(1):176-84.
Specimen size and porosity can introduce error into microCT-based tissue mineral density measurements.
Yu PB, Deng DY, Lai CS, Hong CC, Cuny GD, Bouxsein ML, Hong DW, McManus PM, Katagiri T, Sachidanandan C, Kamiya N, Fukuda T, Mishina Y, Peterson RT, Bloch KD
BMP type I receptor inhibition reduces heterotopic [corrected] ossification. Nat Med. 2008 Dec; 14(12):1363-9.
BMP type I receptor inhibition reduces heterotopic [corrected] ossification.
Sornay-Rendu E, Boutroy S, Munoz F, Bouxsein ML
Cortical and trabecular architecture are altered in postmenopausal women with fractures. Osteoporos Int. 2009 Aug; 20(8):1291-7.
Cortical and trabecular architecture are altered in postmenopausal women with fractures.
Beta-arrestin-biased parathyroid hormone ligands: a new approach to the development of agents that stimulate bone formation. Sci Transl Med. 2009 Oct 07; 1(1):1ps1.
Beta-arrestin-biased parathyroid hormone ligands: a new approach to the development of agents that stimulate bone formation.
Craig ZR, Marion SL, Funk JL, Bouxsein ML, Hoyer PB
Retaining Residual Ovarian Tissue following Ovarian Failure Has Limited Influence on Bone Loss in Aged Mice. J Osteoporos. 2010 Jun 29; 2010.
Retaining Residual Ovarian Tissue following Ovarian Failure Has Limited Influence on Bone Loss in Aged Mice.
Whittier DE, Manske SL, Kiel DP, Bouxsein M, Boyd SK
Harmonizing finite element modelling for non-invasive strength estimation by high-resolution peripheral quantitative computed tomography. J Biomech. 2018 10 26; 80:63-71.
Harmonizing finite element modelling for non-invasive strength estimation by high-resolution peripheral quantitative computed tomography.
Lindeman KG, Greenblatt LB, Rourke C, Bouxsein ML, Finkelstein JS, Yu EW
Longitudinal 5-Year Evaluation of Bone Density and Microarchitecture After Roux-en-Y Gastric Bypass Surgery. J Clin Endocrinol Metab. 2018 11 01; 103(11):4104-4112.
Longitudinal 5-Year Evaluation of Bone Density and Microarchitecture After Roux-en-Y Gastric Bypass Surgery.
Lane SW, De Vita S, Alexander KA, Karaman R, Milsom MD, Dorrance AM, Purdon A, Louis L, Bouxsein ML, Williams DA
Rac signaling in osteoblastic cells is required for normal bone development but is dispensable for hematopoietic development. Blood. 2012 Jan 19; 119(3):736-44.
Rac signaling in osteoblastic cells is required for normal bone development but is dispensable for hematopoietic development.
Samelson EJ, Christiansen BA, Demissie S, Broe KE, Louie-Gao Q, Cupples LA, Roberts BJ, Manoharam R, D'Agostino J, Lang T, Kiel DP, Bouxsein ML
QCT measures of bone strength at the thoracic and lumbar spine: the Framingham Study. J Bone Miner Res. 2012 Mar; 27(3):654-63.
QCT measures of bone strength at the thoracic and lumbar spine: the Framingham Study.
Rozental TD, Deschamps LN, Taylor A, Earp B, Zurakowski D, Day CS, Bouxsein ML
Premenopausal women with a distal radial fracture have deteriorated trabecular bone density and morphology compared with controls without a fracture. J Bone Joint Surg Am. 2013 Apr 03; 95(7):633-42.
Premenopausal women with a distal radial fracture have deteriorated trabecular bone density and morphology compared with controls without a fracture.
Fulzele K, Dedic C, Lai F, Bouxsein M, Lotinun S, Baron R, Divieti Pajevic P
Loss of Gsa in osteocytes leads to osteopenia due to sclerostin induced suppression of osteoblast activity. Bone. 2018 12; 117:138-148.
Loss of Gsa in osteocytes leads to osteopenia due to sclerostin induced suppression of osteoblast activity.
Popp KL, Caksa S, Martinez-Betancourt A, Yuan A, Tsai J, Yu EW, Bouxsein ML
Cortical Bone Material Strength Index and Bone Microarchitecture in Postmenopausal Women With Atypical Femoral Fractures. J Bone Miner Res. 2019 01; 34(1):75-82.
Cortical Bone Material Strength Index and Bone Microarchitecture in Postmenopausal Women With Atypical Femoral Fractures.
Ko FC, Van Vliet M, Ellman R, Grasso D, Brooks DJ, Spatz JM, Conlon C, Aguirre JI, Wronski TJ, Bouxsein ML
Treatment With a Soluble Bone Morphogenetic Protein Type 1A Receptor (BMPR1A) Fusion Protein Increases Bone Mass and Bone Formation in Mice Subjected to Hindlimb Unloading. JBMR Plus. 2017 Oct; 1(2):66-72.
Treatment With a Soluble Bone Morphogenetic Protein Type 1A Receptor (BMPR1A) Fusion Protein Increases Bone Mass and Bone Formation in Mice Subjected to Hindlimb Unloading.
Allaire BT, Lu D, Johannesdottir F, Kopperdahl D, Keaveny TM, Jarraya M, Guermazi A, Bredella MA, Samelson EJ, Kiel DP, Anderson DE, Demissie S, Bouxsein ML
Prediction of incident vertebral fracture using CT-based finite element analysis. Osteoporos Int. 2019 Feb; 30(2):323-331.
Prediction of incident vertebral fracture using CT-based finite element analysis.
Melton LJ, Riggs BL, Keaveny TM, Achenbach SJ, Hoffmann PF, Camp JJ, Rouleau PA, Bouxsein ML, Amin S, Atkinson EJ, Robb RA, Khosla S
Structural determinants of vertebral fracture risk. J Bone Miner Res. 2007 Dec; 22(12):1885-92.
Structural determinants of vertebral fracture risk.
Arlot ME, Burt-Pichat B, Roux JP, Vashishth D, Bouxsein ML, Delmas PD
Microarchitecture influences microdamage accumulation in human vertebral trabecular bone. J Bone Miner Res. 2008 Oct; 23(10):1613-8.
Microarchitecture influences microdamage accumulation in human vertebral trabecular bone.
Ackerman KE, Singhal V, Baskaran C, Slattery M, Campoverde Reyes KJ, Toth A, Eddy KT, Bouxsein ML, Lee H, Klibanski A, Misra M
Oestrogen replacement improves bone mineral density in oligo-amenorrhoeic athletes: a randomised clinical trial. Br J Sports Med. 2019 Feb; 53(4):229-236.
Oestrogen replacement improves bone mineral density in oligo-amenorrhoeic athletes: a randomised clinical trial.
Greenspan SL, Bouxsein ML, Melton ME, Kolodny AH, Clair JH, Delucca PT, Stek M, Faulkner KG, Orwoll ES
Precision and discriminatory ability of calcaneal bone assessment technologies. J Bone Miner Res. 1997 Aug; 12(8):1303-13.
Precision and discriminatory ability of calcaneal bone assessment technologies.
Fajardo RJ, Manoharan RK, Pearsall RS, Davies MV, Marvell T, Monnell TE, Ucran JA, Pearsall AE, Khanzode D, Kumar R, Underwood KW, Roberts B, Seehra J, Bouxsein ML
Treatment with a soluble receptor for activin improves bone mass and structure in the axial and appendicular skeleton of female cynomolgus macaques (Macaca fascicularis). Bone. 2010 Jan; 46(1):64-71.
Treatment with a soluble receptor for activin improves bone mass and structure in the axial and appendicular skeleton of female cynomolgus macaques (Macaca fascicularis).
Maridas DE, Rendina-Ruedy E, Helderman RC, DeMambro VE, Brooks D, Guntur AR, Lanske B, Bouxsein ML, Rosen CJ
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Progenitor recruitment and adipogenic lipolysis contribute to the anabolic actions of parathyroid hormone on the skeleton. FASEB J. 2019 02; 33(2):2885-2898.
Progenitor recruitment and adipogenic lipolysis contribute to the anabolic actions of parathyroid hormone on the skeleton.
Hughes JM, McKinnon CJ, Taylor KM, Kardouni JR, Bulathsinhala L, Guerriere KI, Popp KL, Bouxsein ML, Proctor SP, Matheny RW
Nonsteroidal Anti-Inflammatory Drug Prescriptions Are Associated With Increased Stress Fracture Diagnosis in the US Army Population. J Bone Miner Res. 2019 03; 34(3):429-436.
Nonsteroidal Anti-Inflammatory Drug Prescriptions Are Associated With Increased Stress Fracture Diagnosis in the US Army Population.
Wagner EB, Granzella NP, Saito H, Newman DJ, Young LR, Bouxsein ML
Partial weight suspension: a novel murine model for investigating adaptation to reduced musculoskeletal loading. J Appl Physiol (1985). 2010 Aug; 109(2):350-7.
Partial weight suspension: a novel murine model for investigating adaptation to reduced musculoskeletal loading.
Guntur AR, Kawai M, Le P, Bouxsein ML, Bornstein S, Green CB, Rosen CJ
Annals of the New York Academy of Sciences
An essential role for the circadian-regulated gene nocturnin in osteogenesis: the importance of local timekeeping in skeletal homeostasis. Ann N Y Acad Sci. 2011 Nov; 1237:58-63.
An essential role for the circadian-regulated gene nocturnin in osteogenesis: the importance of local timekeeping in skeletal homeostasis.
Popp KL, Xu C, Yuan A, Hughes JM, Unnikrishnan G, Reifman J, Bouxsein ML
Trabecular microstructure is influenced by race and sex in Black and White young adults. Osteoporos Int. 2019 Jan; 30(1):201-209.
Trabecular microstructure is influenced by race and sex in Black and White young adults.
Bouxsein ML, Myburgh KH, van der Meulen MC, Lindenberger E, Marcus R
Age-related differences in cross-sectional geometry of the forearm bones in healthy women. Calcif Tissue Int. 1994 Feb; 54(2):113-8.
Age-related differences in cross-sectional geometry of the forearm bones in healthy women.
Kaiser J, Allaire B, Fein PM, Lu D, Jarraya M, Guermazi A, Demissie S, Samelson EJ, Bouxsein ML, Morgan EF
Correspondence between bone mineral density and intervertebral disc degeneration across age and sex. Arch Osteoporos. 2018 11 12; 13(1):123.
Correspondence between bone mineral density and intervertebral disc degeneration across age and sex.
Kuehn F, Adiliaghdam F, Hamarneh SR, Vasan R, Liu E, Liu Y, Ramirez JM, Hoda RS, Munoz AR, Ko FC, Armanini M, Brooks DJ, Bouxsein ML, Demay MB, Hodin RA
Loss of Intestinal Alkaline Phosphatase Leads to Distinct Chronic Changes in Bone Phenotype. J Surg Res. 2018 12; 232:325-331.
Loss of Intestinal Alkaline Phosphatase Leads to Distinct Chronic Changes in Bone Phenotype.
Riggs BL, Melton Iii LJ, Robb RA, Camp JJ, Atkinson EJ, Peterson JM, Rouleau PA, McCollough CH, Bouxsein ML, Khosla S
Population-based study of age and sex differences in bone volumetric density, size, geometry, and structure at different skeletal sites. J Bone Miner Res. 2004 Dec; 19(12):1945-54.
Population-based study of age and sex differences in bone volumetric density, size, geometry, and structure at different skeletal sites.
Rosen CJ, Ackert-Bicknell C, Beamer WG, Nelson T, Adamo M, Cohen P, Bouxsein ML, Horowitz MC
Allelic differences in a quantitative trait locus affecting insulin-like growth factor-I impact skeletal acquisition and body composition. Pediatr Nephrol. 2005 Mar; 20(3):255-60.
Allelic differences in a quantitative trait locus affecting insulin-like growth factor-I impact skeletal acquisition and body composition.
Betz OB, Betz VM, Nazarian A, Pilapil CG, Vrahas MS, Bouxsein ML, Gerstenfeld LC, Einhorn TA, Evans CH
Direct percutaneous gene delivery to enhance healing of segmental bone defects. J Bone Joint Surg Am. 2006 Feb; 88(2):355-65.
Direct percutaneous gene delivery to enhance healing of segmental bone defects.
Wang Y, Wan C, Deng L, Liu X, Cao X, Gilbert SR, Bouxsein ML, Faugere MC, Guldberg RE, Gerstenfeld LC, Haase VH, Johnson RS, Schipani E, Clemens TL
The hypoxia-inducible factor alpha pathway couples angiogenesis to osteogenesis during skeletal development. J Clin Invest. 2007 Jun; 117(6):1616-26.
The hypoxia-inducible factor alpha pathway couples angiogenesis to osteogenesis during skeletal development.
Samelson EJ, Broe KE, Xu H, Yang L, Boyd S, Biver E, Szulc P, Adachi J, Amin S, Atkinson E, Berger C, Burt L, Chapurlat R, Chevalley T, Ferrari S, Goltzman D, Hanley DA, Hannan MT, Khosla S, Liu CT, Lorentzon M, Mellstrom D, Merle B, Nethander M, Rizzoli R, Sornay-Rendu E, Van Rietbergen B, Sundh D, Wong AKO, Ohlsson C, Demissie S, Kiel DP, Bouxsein ML
Cortical and trabecular bone microarchitecture as an independent predictor of incident fracture risk in older women and men in the Bone Microarchitecture International Consortium (BoMIC): a prospective study. Lancet Diabetes Endocrinol. 2019 01; 7(1):34-43.
Cortical and trabecular bone microarchitecture as an independent predictor of incident fracture risk in older women and men in the Bone Microarchitecture International Consortium (BoMIC): a prospective study.
Kim H, Wrann CD, Jedrychowski M, Vidoni S, Kitase Y, Nagano K, Zhou C, Chou J, Parkman VA, Novick SJ, Strutzenberg TS, Pascal BD, Le PT, Brooks DJ, Roche AM, Gerber KK, Mattheis L, Chen W, Tu H, Bouxsein ML, Griffin PR, Baron R, Rosen CJ, Bonewald LF, Spiegelman BM
Irisin Mediates Effects on Bone and Fat via aV Integrin Receptors. Cell. 2018 12 13; 175(7):1756-1768.e17.
Irisin Mediates Effects on Bone and Fat via aV Integrin Receptors.
Michaeli DA, Mirshahi A, Singer J, Rapa FG, Plass DB, Bouxsein ML
Journal of clinical densitometry : the official journal of the International Society for Clinical Densitometry
A new X-ray based osteoporosis screening tool provides accurate and precise assessment of phalanx bone mineral content. J Clin Densitom. 1999; 2(1):23-30.
A new X-ray based osteoporosis screening tool provides accurate and precise assessment of phalanx bone mineral content.
Ultrasound and densitometry of the calcaneus correlate with the failure loads of cadaveric femurs. Calcif Tissue Int. 1995 Feb; 56(2):99-103.
Ultrasound and densitometry of the calcaneus correlate with the failure loads of cadaveric femurs.
Influence of Spinal Loading on Vertebral Fracture
Ferrari SL, Pierroz DD, Glatt V, Goddard DS, Bianchi EN, Lin FT, Manen D, Bouxsein ML
Bone response to intermittent parathyroid hormone is altered in mice null for {beta}-Arrestin2. Endocrinology. 2005 Apr; 146(4):1854-62.
Bone response to intermittent parathyroid hormone is altered in mice null for {beta}-Arrestin2.
Feng Y, Hsu YH, Terwedow H, Chen Cz, Xu X, Niu T, Zang T, Wu D, Tang G, Li Z, Hong X, Wang B, Brain JD, Cummings SR, Rosen C, Bouxsein ML, Xu X
Familial aggregation of bone mineral density and bone mineral content in a Chinese population. Osteoporos Int. 2005 Dec; 16(12):1917-23.
Familial aggregation of bone mineral density and bone mineral content in a Chinese population.
Betz OB, Betz VM, Nazarian A, Egermann M, Gerstenfeld LC, Einhorn TA, Vrahas MS, Bouxsein ML, Evans CH
Delayed administration of adenoviral BMP-2 vector improves the formation of bone in osseous defects. Gene Ther. 2007 Jul; 14(13):1039-44.
Delayed administration of adenoviral BMP-2 vector improves the formation of bone in osseous defects.
Negative Effects of Long-duration Spaceflight on Paraspinal Muscle Morphology. Spine (Phila Pa 1976). 2019 Jun 15; 44(12):879-886.
Negative Effects of Long-duration Spaceflight on Paraspinal Muscle Morphology.
Nielson CM, Bouxsein ML, Freitas SS, Ensrud KE, Orwoll ES
Trochanteric soft tissue thickness and hip fracture in older men. J Clin Endocrinol Metab. 2009 Feb; 94(2):491-6.
Trochanteric soft tissue thickness and hip fracture in older men.
Viguet-Carrin S, Follet H, Gineyts E, Roux JP, Munoz F, Chapurlat R, Delmas PD, Bouxsein ML
Association between collagen cross-links and trabecular microarchitecture properties of human vertebral bone. Bone. 2010 Feb; 46(2):342-7.
Association between collagen cross-links and trabecular microarchitecture properties of human vertebral bone.
Chantry AD, Heath D, Mulivor AW, Pearsall S, Baud'huin M, Coulton L, Evans H, Abdul N, Werner ED, Bouxsein ML, Key ML, Seehra J, Arnett TR, Vanderkerken K, Croucher P
Inhibiting activin-A signaling stimulates bone formation and prevents cancer-induced bone destruction in vivo. J Bone Miner Res. 2010 Dec; 25(12):2633-46.
Inhibiting activin-A signaling stimulates bone formation and prevents cancer-induced bone destruction in vivo.
Biomechanics of vertebral fractures and the vertebral fracture cascade. Curr Osteoporos Rep. 2010 Dec; 8(4):198-204.
Biomechanics of vertebral fractures and the vertebral fracture cascade.
Follet H, Viguet-Carrin S, Burt-Pichat B, Dépalle B, Bala Y, Gineyts E, Munoz F, Arlot M, Boivin G, Chapurlat RD, Delmas PD, Bouxsein ML
Effects of preexisting microdamage, collagen cross-links, degree of mineralization, age, and architecture on compressive mechanical properties of elderly human vertebral trabecular bone. J Orthop Res. 2011 Apr; 29(4):481-8.
Effects of preexisting microdamage, collagen cross-links, degree of mineralization, age, and architecture on compressive mechanical properties of elderly human vertebral trabecular bone.
Boonen S, Wahl DA, Nauroy L, Brandi ML, Bouxsein ML, Goldhahn J, Lewiecki EM, Lyritis GP, Marsh D, Obrant K, Silverman S, Siris E, Akesson K
Balloon kyphoplasty and vertebroplasty in the management of vertebral compression fractures. Osteoporos Int. 2011 Dec; 22(12):2915-34.
Balloon kyphoplasty and vertebroplasty in the management of vertebral compression fractures.
Ebeling PR, Akesson K, Bauer DC, Buchbinder R, Eastell R, Fink HA, Giangregorio L, Guanabens N, Kado D, Kallmes D, Katzman W, Rodriguez A, Wermers R, Wilson HA, Bouxsein ML
The Efficacy and Safety of Vertebral Augmentation: A Second ASBMR Task Force Report. J Bone Miner Res. 2019 01; 34(1):3-21.
The Efficacy and Safety of Vertebral Augmentation: A Second ASBMR Task Force Report.
Bouxsein ML, Eastell R, Lui LY, Wu LA, de Papp AE, Grauer A, Marin F, Cauley JA, Bauer DC, Black DM
Change in Bone Density and Reduction in Fracture Risk: A Meta-Regression of Published Trials. J Bone Miner Res. 2019 04; 34(4):632-642.
Change in Bone Density and Reduction in Fracture Risk: A Meta-Regression of Published Trials.
Pinilla TP, Boardman KC, Bouxsein ML, Myers ER, Hayes WC
Impact direction from a fall influences the failure load of the proximal femur as much as age-related bone loss. Calcif Tissue Int. 1996 Apr; 58(4):231-5.
Impact direction from a fall influences the failure load of the proximal femur as much as age-related bone loss.
Stroncek JD, Shaul JL, Favell D, Hill RS, Huber BM, Howe JG, Bouxsein ML
In vitro injection of osteoporotic cadaveric femurs with a triphasic calcium-based implant confers immediate biomechanical integrity. J Orthop Res. 2019 04; 37(4):908-915.
In vitro injection of osteoporotic cadaveric femurs with a triphasic calcium-based implant confers immediate biomechanical integrity.
Mortreux M, Riveros D, Bouxsein ML, Rutkove SB
Journal of visualized experiments : JoVE
Mimicking a Space Mission to Mars Using Hindlimb Unloading and Partial Weight Bearing in Rats. J Vis Exp. 2019 04 04; (146).
Mimicking a Space Mission to Mars Using Hindlimb Unloading and Partial Weight Bearing in Rats.
Caksa S, Yuan A, Rudolph SE, Yu EW, Popp KL, Bouxsein ML
Influence of soft tissue on bone density and microarchitecture measurements by high-resolution peripheral quantitative computed tomography. Bone. 2019 07; 124:47-52.
Influence of soft tissue on bone density and microarchitecture measurements by high-resolution peripheral quantitative computed tomography.
Sundaramurthy A, Xu C, Hughes JM, Gaffney-Stomberg E, Guerriere KI, Popp KL, Bouxsein ML, Reifman J, Unnikrishnan G
Regional Changes in Density and Microarchitecture in the Ultradistal Tibia of Female Recruits After U.S. Army Basic Combat Training. Calcif Tissue Int. 2019 07; 105(1):68-76.
Regional Changes in Density and Microarchitecture in the Ultradistal Tibia of Female Recruits After U.S. Army Basic Combat Training.
Besschetnova T, Brooks DJ, Hu D, Nagano K, Nustad J, Ominsky M, Mitlak B, Hattersley G, Bouxsein ML, Baron R, Lanske B
Abaloparatide improves cortical geometry and trabecular microarchitecture and increases vertebral and femoral neck strength in a rat model of male osteoporosis. Bone. 2019 07; 124:148-157.
Abaloparatide improves cortical geometry and trabecular microarchitecture and increases vertebral and femoral neck strength in a rat model of male osteoporosis.
Chandler H, Brooks DJ, Hattersley G, Bouxsein ML, Lanske B
Abaloparatide increases bone mineral density and bone strength in ovariectomized rabbits with glucocorticoid-induced osteopenia. Osteoporos Int. 2019 Aug; 30(8):1607-1616.
Abaloparatide increases bone mineral density and bone strength in ovariectomized rabbits with glucocorticoid-induced osteopenia.
Laurie Carrol Guthart Professor of Medicine
Lotinun S, Ishihara Y, Nagano K, Kiviranta R, Carpentier VT, Neff L, Parkman V, Ide N, Hu D, Dann P, Brooks D, Bouxsein ML, Wysolmerski J, Gori F, Baron R
Cathepsin K-deficient osteocytes prevent lactation-induced bone loss and parathyroid hormone suppression. J Clin Invest. 2019 05 21; 129(8):3058-3071.
Cathepsin K-deficient osteocytes prevent lactation-induced bone loss and parathyroid hormone suppression.
Associate Professor of Orthopedic Surgery
Response Letter to the Editor-Diamond et al, JBMR. J Bone Miner Res. 2019 06; 34(6):1185-1186.
Response Letter to the Editor-Diamond et al, JBMR.
Tsai JN, Nishiyama KK, Lin D, Yuan A, Lee H, Bouxsein ML, Leder BZ
Effects of Denosumab and Teriparatide Transitions on Bone Microarchitecture and Estimated Strength: the DATA-Switch HR-pQCT Study. J Bone Miner Res. 2019 May; 34(5):976.
Effects of Denosumab and Teriparatide Transitions on Bone Microarchitecture and Estimated Strength: the DATA-Switch HR-pQCT Study.
XtremeCT II High Resolution Peripheral Computed Tomography Device
Hughes JM, Foulis SA, Taylor KM, Guerriere KI, Walker LA, Hand AF, Popp KL, Gaffney-Stomberg E, Heaton KJ, Sharp MA, Grier TL, Hauret KG, Jones BH, Bouxsein ML, McClung JP, Matheny RW, Proctor SP
A prospective field study of U.S. Army trainees to identify the physiological bases and key factors influencing musculoskeletal injuries: a study protocol. BMC Musculoskelet Disord. 2019 Jun 12; 20(1):282.
A prospective field study of U.S. Army trainees to identify the physiological bases and key factors influencing musculoskeletal injuries: a study protocol.
Assistant Professor of Orthopedic Surgery
Fritz Bradley Talbot and Nathan Bill Talbot Professor of Pediatrics, Emerita
Popp KL, Turkington V, Hughes JM, Xu C, Unnikrishnan G, Reifman J, Bouxsein ML
Skeletal loading score is associated with bone microarchitecture in young adults. Bone. 2019 10; 127:360-366.
Skeletal loading score is associated with bone microarchitecture in young adults.
Correction to: The factor-of-risk biomechanical approach predicts hip fracture in men and women: the Framingham Study. Osteoporos Int. 2019 Sep; 30(9):1897.
Correction to: The factor-of-risk biomechanical approach predicts hip fracture in men and women: the Framingham Study.
Irisin Mediates Effects on Bone and Fat via aV Integrin Receptors. Cell. 2019 Jul 11; 178(2):507-508.
A Moderate Daily Dose of Resveratrol Mitigates Muscle Deconditioning in a Martian Gravity Analog. Front Physiol. 2019; 10:899.
A Moderate Daily Dose of Resveratrol Mitigates Muscle Deconditioning in a Martian Gravity Analog.
Mortreux M, Ko FC, Riveros D, Bouxsein ML, Rutkove SB
Longitudinal time course of muscle impairments during partial weight-bearing in rats. NPJ Microgravity. 2019; 5:20.
Longitudinal time course of muscle impairments during partial weight-bearing in rats.
Nishimori S, O'Meara MJ, Castro CD, Noda H, Cetinbas M, da Silva Martins J, Ayturk U, Brooks DJ, Bruce M, Nagata M, Ono W, Janton CJ, Bouxsein ML, Foretz M, Berdeaux R, Sadreyev RI, Gardella TJ, Jüppner H, Kronenberg HM, Wein MN
Salt-inducible kinases dictate parathyroid hormone 1 receptor action in bone development and remodeling. J Clin Invest. 2019 12 02; 129(12):5187-5203.
Salt-inducible kinases dictate parathyroid hormone 1 receptor action in bone development and remodeling.
Bone material strength in normoglycemic and hyperglycemic black and white older adults. Osteoporos Int. 2019 Dec; 30(12):2429-2435.
Bone material strength in normoglycemic and hyperglycemic black and white older adults.
Bouxsein ML, Eastell R, Liu LY, Wu LA, de Papp AE, Grauer A, Marin F, Cauley JA, Bauer DC, Black DM
Reply to: Change in Bone Density and Reduction in Fracture Risk: A Meta-Regression of Published Trials. J Bone Miner Res. 2019 10; 34(10):1977-1978.
Reply to: Change in Bone Density and Reduction in Fracture Risk: A Meta-Regression of Published Trials.
Biomechanical mechanisms underlying skeletal fragility in older adults with Type 1 diabetes
Long-term fracture risk in older men: the MrOS study
Determinants of bone microarchitectural compromise in youth with type 1 diabetes
Ackerman KE, Singhal V, Slattery M, Eddy KT, Bouxsein ML, Lee H, Klibanski A, Misra M
Effects of Estrogen Replacement on Bone Geometry and Microarchitecture in Adolescent and Young Adult Oligoamenorrheic Athletes: A Randomized Trial. J Bone Miner Res. 2020 02; 35(2):248-260.
Effects of Estrogen Replacement on Bone Geometry and Microarchitecture in Adolescent and Young Adult Oligoamenorrheic Athletes: A Randomized Trial.
Burkhart K, Allaire B, Anderson DE, Lee D, Keaveny TM, Bouxsein ML
Effects of Long-Duration Spaceflight on Vertebral Strength and Risk of Spine Fracture. J Bone Miner Res. 2020 02; 35(2):269-276.
Effects of Long-Duration Spaceflight on Vertebral Strength and Risk of Spine Fracture.
Fazeli PK, Faje AT, Meenaghan E, Russell ST, Resulaj M, Lee H, Rosen CJ, Bouxsein ML, Klibanski A
IGF-1 is associated with estimated bone strength in anorexia nervosa. Osteoporos Int. 2020 Feb; 31(2):259-265.
IGF-1 is associated with estimated bone strength in anorexia nervosa.
Draghici AE, Taylor JA, Bouxsein ML, Shefelbine SJ
Effects of FES-Rowing Exercise on the Time-Dependent Changes in Bone Microarchitecture After Spinal Cord Injury: A Cross-Sectional Investigation. JBMR Plus. 2019 Sep; 3(9):e10200.
Effects of FES-Rowing Exercise on the Time-Dependent Changes in Bone Microarchitecture After Spinal Cord Injury: A Cross-Sectional Investigation.
Noda H, Guo J, Khatri A, Dean T, Reyes M, Armanini M, Brooks DJ, Martins JS, Schipani E, Bouxsein ML, Demay MB, Potts JT, Jüppner H, Gardella TJ
An Inverse Agonist Ligand of the PTH Receptor Partially Rescues Skeletal Defects in a Mouse Model of Jansen's Metaphyseal Chondrodysplasia. J Bone Miner Res. 2020 03; 35(3):540-549.
An Inverse Agonist Ligand of the PTH Receptor Partially Rescues Skeletal Defects in a Mouse Model of Jansen's Metaphyseal Chondrodysplasia.
Buchbinder R, Ebeling PR, Akesson K, Bauer DC, Eastell R, Fink HA, Giangregorio L, Guanabens N, Kado D, Kallmes D, Katzman W, Rodriguez A, Wermers R, Wilson HA, Bouxsein ML
Response to: Some Questions About the Article "The Efficacy and Safety of Vertebral Augmentation: A Second ASBMR Task Force Report". J Bone Miner Res. 2020 01; 35(1):212-213.
Response to: Some Questions About the Article "The Efficacy and Safety of Vertebral Augmentation: A Second ASBMR Task Force Report".
Howe JG, Hill RS, Stroncek JD, Shaul JL, Favell D, Cheng RR, Engelke K, Genant HK, Lee DC, Keaveny TM, Bouxsein ML, Huber B
Treatment of bone loss in proximal femurs of postmenopausal osteoporotic women with AGN1 local osteo-enhancement procedure (LOEP) increases hip bone mineral density and hip strength: a long-term prospective cohort study. Osteoporos Int. 2020 May; 31(5):921-929.
Treatment of bone loss in proximal femurs of postmenopausal osteoporotic women with AGN1 local osteo-enhancement procedure (LOEP) increases hip bone mineral density and hip strength: a long-term prospective cohort study.
Mitchell DM, Caksa S, Joseph T, Bouxsein ML, Misra M
Elevated HbA1c Is Associated with Altered Cortical and Trabecular Microarchitecture in Girls with Type 1 Diabetes. J Clin Endocrinol Metab. 2020 04 01; 105(4).
Elevated HbA1c Is Associated with Altered Cortical and Trabecular Microarchitecture in Girls with Type 1 Diabetes.
Bouxsein ML, Zysset P, Glüer CC, McClung M, Biver E, Pierroz DD, Ferrari SL
Perspectives on the non-invasive evaluation of femoral strength in the assessment of hip fracture risk. Osteoporos Int. 2020 Mar; 31(3):393-408.
Perspectives on the non-invasive evaluation of femoral strength in the assessment of hip fracture risk.
Kaiser J, Allaire B, Fein PM, Lu D, Adams A, Kiel DP, Jarraya M, Guermazi A, Demissie S, Samelson EJ, Bouxsein ML, Morgan EF
Heterogeneity and Spatial Distribution of Intravertebral Trabecular Bone Mineral Density in the Lumbar Spine Is Associated With Prevalent Vertebral Fracture. J Bone Miner Res. 2020 04; 35(4):641-648.
Heterogeneity and Spatial Distribution of Intravertebral Trabecular Bone Mineral Density in the Lumbar Spine Is Associated With Prevalent Vertebral Fracture.
Misra M, Singhal V, Carmine B, Bose A, Kelsey MM, Stanford FC, Bram J, Aidlen J, Inge T, Bouxsein ML, Bredella MA
Bone outcomes following sleeve gastrectomy in adolescents and young adults with obesity versus non-surgical controls. Bone. 2020 05; 134:115290.
Bone outcomes following sleeve gastrectomy in adolescents and young adults with obesity versus non-surgical controls.
Polineni S, Resulaj M, Faje AT, Meenaghan E, Bredella MA, Bouxsein M, Lee H, MacDougald OA, Klibanski A, Fazeli PK
Red and White Blood Cell Counts Are Associated With Bone Marrow Adipose Tissue, Bone Mineral Density, and Bone Microarchitecture in Premenopausal Women. J Bone Miner Res. 2020 06; 35(6):1031-1039.
Red and White Blood Cell Counts Are Associated With Bone Marrow Adipose Tissue, Bone Mineral Density, and Bone Microarchitecture in Premenopausal Women.
Motyl KJ, Bishop KA, DeMambro VE, Bornstein SA, Le P, Kawai M, Lotinun S, Horowitz MC, Baron R, Bouxsein ML, Rosen CJ
Altered thermogenesis and impaired bone remodeling in Misty mice. J Bone Miner Res. 2013 Sep; 28(9):1885-97.
Altered thermogenesis and impaired bone remodeling in Misty mice.
Increasing fluoride content deteriorates rat bone mechanical properties. Bone. 2020 07; 136:115369.
Increasing fluoride content deteriorates rat bone mechanical properties.
Keaveny TM, Clarke BL, Cosman F, Orwoll ES, Siris ES, Khosla S, Bouxsein ML
Biomechanical Computed Tomography analysis (BCT) for clinical assessment of osteoporosis. Osteoporos Int. 2020 Jun; 31(6):1025-1048.
Biomechanical Computed Tomography analysis (BCT) for clinical assessment of osteoporosis.
Ko FC, Mortreux M, Riveros D, Nagy JA, Rutkove SB, Bouxsein ML
Dose-dependent skeletal deficits due to varied reductions in mechanical loading in rats. NPJ Microgravity. 2020; 6:15.
Dose-dependent skeletal deficits due to varied reductions in mechanical loading in rats.
Whittier DE, Boyd SK, Burghardt AJ, Paccou J, Ghasem-Zadeh A, Chapurlat R, Engelke K, Bouxsein ML
Guidelines for the assessment of bone density and microarchitecture in vivo using high-resolution peripheral quantitative computed tomography. Osteoporos Int. 2020 Sep; 31(9):1607-1627.
Guidelines for the assessment of bone density and microarchitecture in vivo using high-resolution peripheral quantitative computed tomography.
Hughes JM, Castellani CM, Popp KL, Guerriere KI, Matheny RW, Nindl BC, Bouxsein ML
The Central Role of Osteocytes in the Four Adaptive Pathways of Bone's Mechanostat. Exerc Sport Sci Rev. 2020 07; 48(3):140-148.
The Central Role of Osteocytes in the Four Adaptive Pathways of Bone's Mechanostat.
Sato T, Verma S, Andrade CDC, Omeara M, Campbell N, Wang JS, Cetinbas M, Lang A, Ausk BJ, Brooks DJ, Sadreyev RI, Kronenberg HM, Lagares D, Uda Y, Pajevic PD, Bouxsein ML, Gross TS, Wein MN
A FAK/HDAC5 signaling axis controls osteocyte mechanotransduction. Nat Commun. 2020 07 01; 11(1):3282.
A FAK/HDAC5 signaling axis controls osteocyte mechanotransduction.
Black DM, Bauer DC, Vittinghoff E, Lui LY, Grauer A, Marin F, Khosla S, de Papp A, Mitlak B, Cauley JA, McCulloch CE, Eastell R, Bouxsein ML
Treatment-related changes in bone mineral density as a surrogate biomarker for fracture risk reduction: meta-regression analyses of individual patient data from multiple randomised controlled trials. Lancet Diabetes Endocrinol. 2020 Aug; 8(8):672-682.
Treatment-related changes in bone mineral density as a surrogate biomarker for fracture risk reduction: meta-regression analyses of individual patient data from multiple randomised controlled trials.
Lindeman KG, Rushin CC, Cheney MC, Bouxsein ML, Hutter MM, Yu EW
Bone Density and Trabecular Morphology at Least 10 Years After Gastric Bypass and Gastric Banding. J Bone Miner Res. 2020 11; 35(11):2132-2142.
Bone Density and Trabecular Morphology at Least 10 Years After Gastric Bypass and Gastric Banding.
The role of GGPS1 and CYP1A1 mutations in atypical femoral fracture
Johannesdottir F, Allaire B, Kopperdahl DL, Keaveny TM, Sigurdsson S, Bredella MA, Anderson DE, Samelson EJ, Kiel DP, Gudnason VG, Bouxsein ML
Bone density and strength from thoracic and lumbar CT scans both predict incident vertebral fractures independently of fracture location. Osteoporos Int. 2021 Feb; 32(2):261-269.
Bone density and strength from thoracic and lumbar CT scans both predict incident vertebral fractures independently of fracture location.
Estell EG, Le PT, Vegting Y, Kim H, Wrann C, Bouxsein ML, Nagano K, Baron R, Spiegelman BM, Rosen CJ
Irisin directly stimulates osteoclastogenesis and bone resorption in vitro and in vivo. Elife. 2020 08 11; 9.
Irisin directly stimulates osteoclastogenesis and bone resorption in vitro and in vivo.
Ramchand SK, David NL, Lee H, Bruce M, Bouxsein ML, Leder BZ, Tsai JN
Effects of Combination Denosumab and High-Dose Teriparatide Administration on Bone Microarchitecture and Estimated Strength: The DATA-HD HR-pQCT Study. J Bone Miner Res. 2021 01; 36(1):41-51.
Effects of Combination Denosumab and High-Dose Teriparatide Administration on Bone Microarchitecture and Estimated Strength: The DATA-HD HR-pQCT Study.
Burkhart K, Grindle D, Bouxsein ML, Anderson DE
Between-session reliability of subject-specific musculoskeletal models of the spine derived from optoelectronic motion capture data. J Biomech. 2020 11 09; 112:110044.
Between-session reliability of subject-specific musculoskeletal models of the spine derived from optoelectronic motion capture data.
Roux JP, Boutroy S, Bouxsein ML, Chapurlat R, Wegrzyn J
Local and global microarchitecture is associated with different features of bone biomechanics. Bone Rep. 2020 Dec; 13:100716.
Local and global microarchitecture is associated with different features of bone biomechanics.
Black DM, Bouxsein ML, Bauer DC, Eastell R
Bone mineral density as a surrogate biomarker for fracture risk reduction - Authors' reply. Lancet Diabetes Endocrinol. 2020 11; 8(11):876.
Bone mineral density as a surrogate biomarker for fracture risk reduction - Authors' reply.
Popp KL, Ackerman KE, Rudolph SE, Johannesdottir F, Hughes JM, Tenforde AS, Bredella MA, Xu C, Unnikrishnan G, Reifman J, Bouxsein ML
Changes in Volumetric Bone Mineral Density Over 12 Months After a Tibial Bone Stress Injury Diagnosis: Implications for Return to Sports and Military Duty. Am J Sports Med. 2021 01; 49(1):226-235.
Changes in Volumetric Bone Mineral Density Over 12 Months After a Tibial Bone Stress Injury Diagnosis: Implications for Return to Sports and Military Duty.
Mokhtarzadeh H, Anderson DE, Allaire BT, Bouxsein ML
Patterns of Load-to-Strength Ratios Along the Spine in a Population-Based Cohort to Evaluate the Contribution of Spinal Loading to Vertebral Fractures. J Bone Miner Res. 2021 04; 36(4):704-711.
Patterns of Load-to-Strength Ratios Along the Spine in a Population-Based Cohort to Evaluate the Contribution of Spinal Loading to Vertebral Fractures.
Putman MS, Greenblatt LB, Bruce M, Joseph T, Lee H, Sawicki G, Uluer A, Sicilian L, Neuringer I, Gordon CM, Bouxsein ML, Finkelstein JS
The Effects of Ivacaftor on Bone Density and Microarchitecture in Children and Adults with Cystic Fibrosis. J Clin Endocrinol Metab. 2021 03 08; 106(3):e1248-e1261.
The Effects of Ivacaftor on Bone Density and Microarchitecture in Children and Adults with Cystic Fibrosis.
Teguh DA, Nustad JL, Craven AE, Brooks DJ, Arlt H, Hu D, Baron R, Lanske B, Bouxsein ML
Abaloparatide treatment increases bone formation, bone density and bone strength without increasing bone resorption in a rat model of hindlimb unloading. Bone. 2021 03; 144:115801.
Abaloparatide treatment increases bone formation, bone density and bone strength without increasing bone resorption in a rat model of hindlimb unloading.
Long term fracture risk and change in peripheral bone in the oldest old men: The MrOS study
Delineating mechanisms of skeletal fragility in older adults with Type 1 Diabetes
Mohrin M, Liu J, Zavala-Solorio J, Bhargava S, Maxwell Trumble J, Brito A, Hu D, Brooks D, Koukos G, Alabdulaaly L, Paw JS, Hake K, Kolumam G, Bouxsein ML, Baron R, Kutskova Y, Freund A
Inhibition of longevity regulator PAPP-A modulates tissue homeostasis via restraint of mesenchymal stromal cells. Aging Cell. 2021 03; 20(3):e13313.
Inhibition of longevity regulator PAPP-A modulates tissue homeostasis via restraint of mesenchymal stromal cells.
Dose-dependent skeletal deficits due to varied reductions in mechanical loading in rats. NPJ Microgravity. 2020 May 18; 6(1):15.
Singhal V, Bose A, Slattery M, Haines MS, Goldstein MA, Gupta N, Brigham KS, Ebrahimi S, Javaras KN, Bouxsein ML, Eddy KT, Miller KK, Schoenfeld D, Klibanski A, Misra M
Effect of Transdermal Estradiol and Insulin-like Growth Factor-1 on Bone Endpoints of Young Women With Anorexia Nervosa. J Clin Endocrinol Metab. 2021 06 16; 106(7):2021-2035.
Effect of Transdermal Estradiol and Insulin-like Growth Factor-1 on Bone Endpoints of Young Women With Anorexia Nervosa.
Papapoulos S, Bone H, Cosman F, Dempster DW, McClung MR, Nakamura T, Restrepo JFM, Bouxsein ML, Cohn D, de Papp A, Massaad R, Santora A
Incidence of Hip and Subtrochanteric/Femoral Shaft Fractures in Postmenopausal Women With Osteoporosis in the Phase 3 Long-Term Odanacatib Fracture Trial. J Bone Miner Res. 2021 07; 36(7):1225-1234.
Incidence of Hip and Subtrochanteric/Femoral Shaft Fractures in Postmenopausal Women With Osteoporosis in the Phase 3 Long-Term Odanacatib Fracture Trial.
Sewastianik T, Straubhaar JR, Zhao JJ, Samur MK, Adler K, Tanton HE, Shanmugam V, Nadeem O, Dennis PS, Pillai V, Wang J, Jiang M, Lin J, Huang Y, Brooks D, Bouxsein M, Dorfman DM, Pinkus GS, Robbiani DF, Ghobrial IM, Budnik B, Jarolim P, Munshi NC, Anderson KC, Carrasco RD
miR-15a/16-1 deletion in activated B cells promotes plasma cell and mature B-cell neoplasms. Blood. 2021 04 08; 137(14):1905-1919.
miR-15a/16-1 deletion in activated B cells promotes plasma cell and mature B-cell neoplasms.
Rudolph SE, Caksa S, Gehman S, Garrahan M, Hughes JM, Tenforde AS, Ackerman KE, Bouxsein ML, Popp KL
Medicine and science in sports and exercise
Physical Activity, Menstrual History, and Bone Microarchitecture in Female Athletes with Multiple Bone Stress Injuries. Med Sci Sports Exerc. 2021 10 01; 53(10):2182-2189.
Physical Activity, Menstrual History, and Bone Microarchitecture in Female Athletes with Multiple Bone Stress Injuries.
Rocket science: what spaceflight can tell us about skeletal health on Earth. Br J Sports Med. 2021 Nov; 55(21):1182-1183.
Rocket science: what spaceflight can tell us about skeletal health on Earth.
Kwok AT, Mohamed NS, Plate JF, Yammani RR, Rosas S, Bateman TA, Livingston E, Moore JE, Kerr BA, Lee J, Furdui CM, Tan L, Bouxsein ML, Ferguson VL, Stodieck LS, Zawieja DC, Delp MD, Mao XW, Willey JS
Spaceflight and hind limb unloading induces an arthritic phenotype in knee articular cartilage and menisci of rodents. Sci Rep. 2021 05 18; 11(1):10469.
Spaceflight and hind limb unloading induces an arthritic phenotype in knee articular cartilage and menisci of rodents.
McLean RR, Samelson EJ, Lorbergs AL, Broe KE, Hannan MT, Boyd SK, Bouxsein ML, Kiel DP
Higher Hand Grip Strength Is Associated With Greater Radius Bone Size and Strength in Older Men and Women: The Framingham Osteoporosis Study. JBMR Plus. 2021 May; 5(5):e10485.
Higher Hand Grip Strength Is Associated With Greater Radius Bone Size and Strength in Older Men and Women: The Framingham Osteoporosis Study.
van den Bergh JP, Szulc P, Cheung AM, Bouxsein M, Engelke K, Chapurlat R
The clinical application of high-resolution peripheral computed tomography (HR-pQCT) in adults: state of the art and future directions. Osteoporos Int. 2021 Aug; 32(8):1465-1485.
The clinical application of high-resolution peripheral computed tomography (HR-pQCT) in adults: state of the art and future directions.
Lelis Carvalho A, Treyball A, Brooks DJ, Costa S, Neilson RJ, Reagan MR, Bouxsein ML, Motyl KJ
TRPM8 modulates temperature regulation in a sex-dependent manner without affecting cold-induced bone loss. PLoS One. 2021; 16(6):e0231060.
TRPM8 modulates temperature regulation in a sex-dependent manner without affecting cold-induced bone loss.
Al-Barghouthi BM, Mesner LD, Calabrese GM, Brooks D, Tommasini SM, Bouxsein ML, Horowitz MC, Rosen CJ, Nguyen K, Haddox S, Farber EA, Onengut-Gumuscu S, Pomp D, Farber CR
Systems genetics in diversity outbred mice inform BMD GWAS and identify determinants of bone strength. Nat Commun. 2021 06 07; 12(1):3408.
Systems genetics in diversity outbred mice inform BMD GWAS and identify determinants of bone strength.
Tang CC, Castro Andrade CD, O'Meara MJ, Yoon SH, Sato T, Brooks DJ, Bouxsein ML, Martins JDS, Wang J, Gray NS, Misof B, Roschger P, Blouin S, Klaushofer K, Velduis-Vlug A, Vegting Y, Rosen CJ, O'Connell D, Sundberg TB, Xavier RJ, Ung P, Schlessinger A, Kronenberg HM, Berdeaux R, Foretz M, Wein MN
Dual targeting of salt inducible kinases and CSF1R uncouples bone formation and bone resorption. Elife. 2021 06 23; 10.
Dual targeting of salt inducible kinases and CSF1R uncouples bone formation and bone resorption.
Bredella MA, Ferrone CR, Tannous BA, Patel KA, Levy AS, Bouxsein ML
Promoting Women in Academic Medicine during COVID-19 and Beyond. J Gen Intern Med. 2021 10; 36(10):3292-3294.
Promoting Women in Academic Medicine during COVID-19 and Beyond.
Alemi MM, Burkhart KA, Lynch AC, Allaire BT, Mousavi SJ, Zhang C, Bouxsein ML, Anderson DE
Frontiers in bioengineering and biotechnology
The Influence of Kinematic Constraints on Model Performance During Inverse Kinematics Analysis of the Thoracolumbar Spine. Front Bioeng Biotechnol. 2021; 9:688041.
The Influence of Kinematic Constraints on Model Performance During Inverse Kinematics Analysis of the Thoracolumbar Spine.
Eastell R, Vittinghoff E, Lui LY, McCulloch CE, Pavo I, Chines A, Khosla S, Cauley JA, Mitlak B, Bauer DC, Bouxsein M, Black DM
Validation of the Surrogate Threshold Effect for Change in Bone Mineral Density as a Surrogate Endpoint for Fracture Outcomes: The FNIH-ASBMR SABRE Project. J Bone Miner Res. 2022 01; 37(1):29-35.
Validation of the Surrogate Threshold Effect for Change in Bone Mineral Density as a Surrogate Endpoint for Fracture Outcomes: The FNIH-ASBMR SABRE Project.
Bredella MA, Fazeli PK, Bourassa J, Rosen CJ, Bouxsein ML, Klibanski A, Miller KK
The effect of short-term high-caloric feeding and fasting on bone microarchitecture. Bone. 2022 01; 154:116214.
The effect of short-term high-caloric feeding and fasting on bone microarchitecture.
Rosa-Caldwell ME, Mortreux M, Kaiser UB, Sung DM, Bouxsein ML, Dunlap KR, Greene NP, Rutkove SB
The oestrous cycle and skeletal muscle atrophy: Investigations in rodent models of muscle loss. Exp Physiol. 2021 12; 106(12):2472-2488.
The oestrous cycle and skeletal muscle atrophy: Investigations in rodent models of muscle loss.
Spatz JM, Ko FC, Ayturk UM, Warman ML, Bouxsein ML
RNAseq and RNA molecular barcoding reveal differential gene expression in cortical bone following hindlimb unloading in female mice. PLoS One. 2021; 16(10):e0250715.
RNAseq and RNA molecular barcoding reveal differential gene expression in cortical bone following hindlimb unloading in female mice.
Rozental TD, Merchan N, Johannesdottir F, Lechtig A, Earp BE, Harper CM, Bouxsein ML
Longitudinal Changes in Serum Markers of Bone Metabolism and Bone Material Strength in Premenopausal Women with Distal Radial Fracture. J Bone Joint Surg Am. 2022 01 05; 104(1):15-23.
Longitudinal Changes in Serum Markers of Bone Metabolism and Bone Material Strength in Premenopausal Women with Distal Radial Fracture.
Johannesdottir F, Putman MS, Burnett-Bowie SM, Finkelstein JS, Yu EW, Bouxsein ML
Age-Related Changes in Bone Density, Microarchitecture, and Strength in Postmenopausal Black and White Women: The SWAN Longitudinal HR-pQCT Study. J Bone Miner Res. 2022 01; 37(1):41-51.
Age-Related Changes in Bone Density, Microarchitecture, and Strength in Postmenopausal Black and White Women: The SWAN Longitudinal HR-pQCT Study.
Kim PG, Niroula A, Shkolnik V, McConkey M, Lin AE, Slabicki M, Kemp JP, Bick A, Gibson CJ, Griffin G, Sekar A, Brooks DJ, Wong WJ, Cohen DN, Uddin MM, Shin WJ, Pirruccello J, Tsai JM, Agrawal M, Kiel DP, Bouxsein ML, Richards JB, Evans DM, Wein MN, Charles JF, Jaiswal S, Natarajan P, Ebert BL
Dnmt3a-mutated clonal hematopoiesis promotes osteoporosis. J Exp Med. 2021 12 06; 218(12).
Dnmt3a-mutated clonal hematopoiesis promotes osteoporosis.
Wang JS, Kamath T, Mazur CM, Mirzamohammadi F, Rotter D, Hojo H, Castro CD, Tokavanich N, Patel R, Govea N, Enishi T, Wu Y, da Silva Martins J, Bruce M, Brooks DJ, Bouxsein ML, Tokarz D, Lin CP, Abdul A, Macosko EZ, Fiscaletti M, Munns CF, Ryder P, Kost-Alimova M, Byrne P, Cimini B, Fujiwara M, Kronenberg HM, Wein MN
Control of osteocyte dendrite formation by Sp7 and its target gene osteocrin. Nat Commun. 2021 11 01; 12(1):6271.
Control of osteocyte dendrite formation by Sp7 and its target gene osteocrin.
Shaul JL, Hill RS, Bouxsein ML, Burr DB, Tilton AK, Howe JG
AGN1 implant material to treat bone loss: Resorbable implant forms normal bone with and without alendronate in a canine critical size humeral defect model. Bone. 2022 01; 154:116246.
AGN1 implant material to treat bone loss: Resorbable implant forms normal bone with and without alendronate in a canine critical size humeral defect model.
Spanyer J, Barber LA, Lands H, Brown A, Bouxsein M, Heng M, Yakkanti M
Health-related quality of life outcomes after surgical treatment of atypical femur fractures: a multicenter retrospective cohort study. JBMR Plus. 2021 Nov; 5(11):e10514.
Health-related quality of life outcomes after surgical treatment of atypical femur fractures: a multicenter retrospective cohort study.
Gaffney-Stomberg E, Hughes JM, Guerriere KI, Staab JS, Cable SJ, Bouxsein ML, McClung JP
Once daily calcium (1000 mg) and vitamin D (1000 IU) supplementation during military training prevents increases in biochemical markers of bone resorption but does not affect tibial microarchitecture in Army recruits. Bone. 2022 02; 155:116269.
Once daily calcium (1000 mg) and vitamin D (1000 IU) supplementation during military training prevents increases in biochemical markers of bone resorption but does not affect tibial microarchitecture in Army recruits.
Whittier DE, Samelson EJ, Hannan MT, Burt LA, Hanley DA, Biver E, Szulc P, Sornay-Rendu E, Merle B, Chapurlat R, Lespessailles E, Wong AKO, Goltzman D, Khosla S, Ferrari S, Bouxsein ML, Kiel DP, Boyd SK
Bone Microarchitecture Phenotypes Identified in Older Adults Are Associated With Different Levels of Osteoporotic Fracture Risk. J Bone Miner Res. 2022 03; 37(3):428-439.
Bone Microarchitecture Phenotypes Identified in Older Adults Are Associated With Different Levels of Osteoporotic Fracture Risk.
Tenforde AS, Outerleys J, Bouxsein ML, Buckless CG, Besier T, Davis IS, Bredella MA
Metatarsal Bone Marrow Edema on Magnetic Resonance Imaging and Its Correlation to Bone Stress Injuries in Male Collegiate Basketball Players. Orthop J Sports Med. 2022 Jan; 10(1):23259671211063505.
Metatarsal Bone Marrow Edema on Magnetic Resonance Imaging and Its Correlation to Bone Stress Injuries in Male Collegiate Basketball Players.
Correction to: Fracture Prediction by Computed Tomography and Finite Element Analysis: Current and Future Perspectives. Curr Osteoporos Rep. 2022 Oct; 20(5):364.
Correction to: Fracture Prediction by Computed Tomography and Finite Element Analysis: Current and Future Perspectives.
Treyball A, Bergeron AC, Brooks DJ, Langlais AL, Hashmi H, Nagano K, Barlow D, Neilson RJ, Roy TA, Nevola KT, Houseknecht KL, Baron R, Bouxsein ML, Guntur AR, Motyl KJ
Propranolol Promotes Bone Formation and Limits Resorption Through Novel Mechanisms During Anabolic Parathyroid Hormone Treatment in Female C57BL/6J Mice. J Bone Miner Res. 2022 05; 37(5):954-971.
Propranolol Promotes Bone Formation and Limits Resorption Through Novel Mechanisms During Anabolic Parathyroid Hormone Treatment in Female C57BL/6J Mice.
Harris BT, Le PT, Da Silva Martins J, Alabdulaaly L, Baron R, Bouxsein ML, Rosen CJ, Pletch AN
Insulin-like growth factor binding protein 2 null mice (Igfbp2-/-) are protected against trabecular bone loss after vertical sleeve gastrectomy. Surg Endosc. 2022 09; 36(9):6984-6996.
Insulin-like growth factor binding protein 2 null mice (Igfbp2-/-) are protected against trabecular bone loss after vertical sleeve gastrectomy.
Popp KL, Outerleys J, Gehman S, Garrahan M, Rudolph S, Loranger E, Ackerman KE, Tenforde AS, Bouxsein ML, Davis IS
Impact loading in female runners with single and multiple bone stress injuries during fresh and exerted conditions. J Sport Health Sci. 2023 05; 12(3):406-413.
Impact loading in female runners with single and multiple bone stress injuries during fresh and exerted conditions.
Popp KL, Cooke LM, Bouxsein ML, Hughes JM
Impact of Low Energy Availability on Skeletal Health in Physically Active Adults. Calcif Tissue Int. 2022 05; 110(5):605-614.
Impact of Low Energy Availability on Skeletal Health in Physically Active Adults.
Hoenig T, Ackerman KE, Beck BR, Bouxsein ML, Burr DB, Hollander K, Popp KL, Rolvien T, Tenforde AS, Warden SJ
Bone stress injuries. Nat Rev Dis Primers. 2022 04 28; 8(1):26.
Gehman S, Ackerman KE, Caksa S, Rudolph SE, Hughes JM, Garrahan M, Tenforde AS, Bouxsein ML, Popp KL
International journal of sport nutrition and exercise metabolism
Restrictive Eating and Prior Low-Energy Fractures Are Associated With History of Multiple Bone Stress Injuries. Int J Sport Nutr Exerc Metab. 2022 Sep 01; 32(5):325-333.
Restrictive Eating and Prior Low-Energy Fractures Are Associated With History of Multiple Bone Stress Injuries.
Daley EJ, Yoon SH, Reyes M, Bruce M, Brooks DJ, Bouxsein M, Potts JT, Kronenberg HM, Wein MN, Lanske B, Jüppner H, Gardella TJ
Actions of Parathyroid Hormone Ligand Analogues in Humanized PTH1R Knockin Mice. Endocrinology. 2022 07 01; 163(7).
Actions of Parathyroid Hormone Ligand Analogues in Humanized PTH1R Knockin Mice.
Nimmala S, Kaur S, Singhal V, Mitchell DM, Stanford FC, Bouxsein ML, Lauze M, Huynh C, Pedreira CC, Lee H, Bredella MA, Misra M
Changes in Sex Steroids and Enteric Peptides After Sleeve Gastrectomy in Youth in Relation to Changes in Bone Parameters. J Clin Endocrinol Metab. 2022 08 18; 107(9):e3747-e3758.
Changes in Sex Steroids and Enteric Peptides After Sleeve Gastrectomy in Youth in Relation to Changes in Bone Parameters.
Reid KF, Storer TW, Pencina KM, Valderrabano R, Latham NK, Wilson L, Ghattas C, Dixon R, Nunes A, Bajdek N, Huang G, Skeels SE, Lin AP, Merugumala SM, Liao HJ, Bouxsein ML, Zafonte RD, Bhasin S
A multimodality intervention to improve musculoskeletal health, function, metabolism, and well-being in spinal cord injury: study protocol for the FIT-SCI randomized controlled trial. BMC Musculoskelet Disord. 2022 May 25; 23(1):493.
A multimodality intervention to improve musculoskeletal health, function, metabolism, and well-being in spinal cord injury: study protocol for the FIT-SCI randomized controlled trial.
Banks JJ, Alemi MM, Allaire BT, Lynch AC, Bouxsein ML, Anderson DE
Using static postures to estimate spinal loading during dynamic lifts with participant-specific thoracolumbar musculoskeletal models. Appl Ergon. 2023 Jan; 106:103869.
Using static postures to estimate spinal loading during dynamic lifts with participant-specific thoracolumbar musculoskeletal models.
Tarantino U, Cariati I, Greggi C, Iundusi R, Gasbarra E, Iolascon G, Kurth A, Akesson KE, Bouxsein M, Tranquilli Leali P, Civinini R, Falez F, Brandi ML
Gaps and alternative surgical and non-surgical approaches in the bone fragility management: an updated review. Osteoporos Int. 2022 Dec; 33(12):2467-2478.
Gaps and alternative surgical and non-surgical approaches in the bone fragility management: an updated review.
Garrahan M, Gehman S, Rudolph SE, Tenforde AS, Ackerman KE, Popp KL, Bouxsein ML, Sahni S
Serum 25-Hydroxyvitamin D is Associated With Bone Microarchitecture and Strength in a Multiracial Cohort of Young Adults. J Clin Endocrinol Metab. 2022 08 18; 107(9):e3679-e3688.
Serum 25-Hydroxyvitamin D is Associated With Bone Microarchitecture and Strength in a Multiracial Cohort of Young Adults.
Singhal V, Huynh C, Nimmala S, Mitchell DM, Pedreira CC, Bader A, Flanders K, Zheng J, Bouxsein ML, Misra M, Bredella MA
Load-to-strength ratio at the radius is higher in adolescent and young adult females with obesity compared to normal-weight controls. Bone. 2022 11; 164:116515.
Load-to-strength ratio at the radius is higher in adolescent and young adult females with obesity compared to normal-weight controls.
Mazur CM, Castro Andrade CD, Tokavanich N, Sato T, Bruce M, Brooks DJ, Bouxsein ML, Wang JS, Wein MN
Partial prevention of glucocorticoid-induced osteocyte deterioration in young male mice with osteocrin gene therapy. iScience. 2022 Sep 16; 25(9):105019.
Partial prevention of glucocorticoid-induced osteocyte deterioration in young male mice with osteocrin gene therapy.
Mitchell DM, Singhal V, Animashaun A, Bose A, Carmine B, Stanford FC, Inge TH, Kelsey MM, Lee H, Bouxsein ML, Yu EW, Bredella MA, Misra M
Skeletal Effects of Sleeve Gastrectomy in Adolescents and Young Adults: A 2-Year Longitudinal Study. J Clin Endocrinol Metab. 2023 03 10; 108(4):847-857.
Skeletal Effects of Sleeve Gastrectomy in Adolescents and Young Adults: A 2-Year Longitudinal Study.
Lewiecki EM, Bilezikian JP, Binkley N, Bouxsein ML, Bukata SV, Dempster DW, Drake MT, McClung MR, Miller PD, Rosenthal E, Tosi LL
Proceedings of the 2022 Santa Fe Bone Symposium: Current Concepts in the Care of Patients with Osteoporosis and Metabolic Bone Diseases. J Clin Densitom. 2022 Oct-Dec; 25(4):649-667.
Proceedings of the 2022 Santa Fe Bone Symposium: Current Concepts in the Care of Patients with Osteoporosis and Metabolic Bone Diseases.
Guerriere KI, Castellani CM, Popp KL, Bouxsein ML, Hughes JM
Experimental biology and medicine (Maywood, N.J.)
Unraveling the physiologic paradoxes that underlie exercise prescription for stress fracture prevention. Exp Biol Med (Maywood). 2022 10; 247(20):1833-1839.
Unraveling the physiologic paradoxes that underlie exercise prescription for stress fracture prevention.
Eastell R, Vittinghoff E, Lui LY, Ewing SK, Schwartz AV, Bauer DC, Black DM, Bouxsein ML
Diabetes Mellitus and the Benefit of Antiresorptive Therapy on Fracture Risk. J Bone Miner Res. 2022 11; 37(11):2121-2131.
Diabetes Mellitus and the Benefit of Antiresorptive Therapy on Fracture Risk.
Dang T, Faje AT, Meenaghan E, Bredella MA, Bouxsein ML, Klibanski A, Fazeli PK
Bone marrow adipose tissue is associated with fracture history in anorexia nervosa. Osteoporos Int. 2022 Dec; 33(12):2619-2627.
Bone marrow adipose tissue is associated with fracture history in anorexia nervosa.
Ramchand SK, David NL, Lee H, Bruce M, Bouxsein ML, Tsai JN, Leder BZ
The Effect of Zoledronic Acid on Bone Microarchitecture and Strength after Denosumab and Teriparatide Administration: DATA-HD Study Extension. J Bone Miner Res. 2023 01; 38(1):26-34.
The Effect of Zoledronic Acid on Bone Microarchitecture and Strength after Denosumab and Teriparatide Administration: DATA-HD Study Extension.
Zahedi B, Daley EJ, Brooks DJ, Bruce M, Townsend RL, Berthoud HR, Bouxsein ML, Yu EW
The PYY/Y2R-deficient male mouse is not protected from bone loss due to Roux-en-Y gastric bypass. Bone. 2023 02; 167:116608.
The PYY/Y2R-deficient male mouse is not protected from bone loss due to Roux-en-Y gastric bypass.
Carvalho AL, Brooks DJ, Barlow D, Langlais AL, Morrill B, Houseknecht KL, Bouxsein ML, Lian JB, King T, Farina NH, Motyl KJ
Sustained Morphine Delivery Suppresses Bone Formation and Alters Metabolic and Circulating miRNA Profiles in Male C57BL/6J Mice. J Bone Miner Res. 2022 11; 37(11):2226-2243.
Sustained Morphine Delivery Suppresses Bone Formation and Alters Metabolic and Circulating miRNA Profiles in Male C57BL/6J Mice.
Abitante TJ, Bouxsein ML, Duda KR, Newman DJ
Aerospace medicine and human performance
Potential of Neuromuscular Electrical Stimulation as a Bone Loss Countermeasure in Microgravity. Aerosp Med Hum Perform. 2022 Nov 01; 93(11):774-782.
Potential of Neuromuscular Electrical Stimulation as a Bone Loss Countermeasure in Microgravity.
Reynolds RJ, Scott RT, Turner RT, Iwaniec UT, Bouxsein ML, Sanders LM, Antonsen EL
Validating Causal Diagrams of Human Health Risks for Spaceflight: An Example Using Bone Data from Rodents. Biomedicines. 2022 Sep 05; 10(9).
Validating Causal Diagrams of Human Health Risks for Spaceflight: An Example Using Bone Data from Rodents.
Hess M, Allaire B, Gao KT, Tibrewala R, Inamdar G, Bharadwaj U, Chin C, Pedoia V, Bouxsein M, Anderson D, Majumdar S
Deep Learning for Multi-Tissue Segmentation and Fully Automatic Personalized Biomechanical Models from BACPAC Clinical Lumbar Spine MRI. Pain Med. 2023 08 04; 24(Suppl 1):S139-S148.
Deep Learning for Multi-Tissue Segmentation and Fully Automatic Personalized Biomechanical Models from BACPAC Clinical Lumbar Spine MRI.
Morse KW, Moore H, Kumagai H, Hahn W, Koo A, Meyers KN, Bouxsein ML, Brooks DJ, Lanske B, Iyer S, Cunningham M
Abaloparatide Enhances Fusion and Bone Formation in a Rabbit Spinal Arthrodesis Model. Spine (Phila Pa 1976). 2022 Nov 15; 47(22):1607-1612.
Abaloparatide Enhances Fusion and Bone Formation in a Rabbit Spinal Arthrodesis Model.
Sato T, Andrade CDC, Yoon SH, Zhao Y, Greenlee WJ, Weber PC, Viswanathan U, Kulp J, Brooks DJ, Demay MB, Bouxsein ML, Mitlak B, Lanske B, Wein MN
Structure-based design of selective, orally available salt-inducible kinase inhibitors that stimulate bone formation in mice. Proc Natl Acad Sci U S A. 2022 12 13; 119(50):e2214396119.
Structure-based design of selective, orally available salt-inducible kinase inhibitors that stimulate bone formation in mice.
Liu CT, Tsai T, Allaire BT, Bouxsein ML, Hannan MT, Travison TG, Kiel DP
Accumulation in Visceral Adipose Tissue Over 6 Years Is Associated With Lower Paraspinal Muscle Density. J Clin Endocrinol Metab. 2023 05 17; 108(6):1348-1354.
Accumulation in Visceral Adipose Tissue Over 6 Years Is Associated With Lower Paraspinal Muscle Density.
Rufus-Membere P, Holloway-Kew KL, Diez-Perez A, Appelman-Dijkstra NM, Bouxsein ML, Eriksen EF, Farr JN, Khosla S, Kotowicz MA, Nogues X, Rubin M, Pasco JA
Reference Intervals for Bone Impact Microindentation in Healthy Adults: A Multi-Centre International Study. Calcif Tissue Int. 2023 03; 112(3):338-349.
Reference Intervals for Bone Impact Microindentation in Healthy Adults: A Multi-Centre International Study.
Huber FA, Singhal V, Tuli S, Stanford FC, Carmine B, Bouxsein ML, Misra M, Bredella MA
Biomechanical CT to Assess Bone After Sleeve Gastrectomy in Adolescents With Obesity: A Prospective Longitudinal Study. J Bone Miner Res. 2023 07; 38(7):933-942.
Biomechanical CT to Assess Bone After Sleeve Gastrectomy in Adolescents With Obesity: A Prospective Longitudinal Study.
Haines MS, Kaur S, Scarff G, Lauze M, Gerweck A, Slattery M, Oreskovic NM, Ackerman KE, Tenforde AS, Popp KL, Bouxsein ML, Miller KK, Misra M
Male Runners With Lower Energy Availability Have Impaired Skeletal Integrity Compared to Nonathletes. J Clin Endocrinol Metab. 2023 09 18; 108(10):e1063-e1073.
Male Runners With Lower Energy Availability Have Impaired Skeletal Integrity Compared to Nonathletes.
Huber FA, Singhal V, Tuli S, Becetti I, López López AP, Bouxsein ML, Misra M, Bredella MA
Two-year Skeletal Effects of Sleeve Gastrectomy in Adolescents with Obesity Assessed with Quantitative CT and MR Spectroscopy. Radiology. 2023 06; 307(5):e223256.
Two-year Skeletal Effects of Sleeve Gastrectomy in Adolescents with Obesity Assessed with Quantitative CT and MR Spectroscopy.
Alemi MM, Banks JJ, Lynch AC, Allaire BT, Bouxsein ML, Anderson DE
EMG Validation of a Subject-Specific Thoracolumbar Spine Musculoskeletal Model During Dynamic Activities in Older Adults. Ann Biomed Eng. 2023 Oct; 51(10):2313-2322.
EMG Validation of a Subject-Specific Thoracolumbar Spine Musculoskeletal Model During Dynamic Activities in Older Adults.
Hughes JM, Taylor KM, Guerriere KI, Smith NI, Staab JS, Walker LA, Staab JE, Bartlett PM, Spiering BA, Nguyen VT, Proctor SP, Foulis SA, Bouxsein ML, Popp KL
Changes in Distal Tibial Microarchitecture During Eight Weeks of U.S. Army Basic Combat Training Differ by Sex and Race. JBMR Plus. 2023 Apr; 7(4):e10719.
Changes in Distal Tibial Microarchitecture During Eight Weeks of U.S. Army Basic Combat Training Differ by Sex and Race.
Rosa-Caldwell ME, Mortreux M, Wadhwa A, Kaiser UB, Sung DM, Bouxsein ML, Rutkove SB
Influence of gonadectomy on muscle health in micro- and partial-gravity environments in rats. J Appl Physiol (1985). 2023 06 01; 134(6):1438-1449.
Influence of gonadectomy on muscle health in micro- and partial-gravity environments in rats.
A Fracture Risk Assessment Tool for High Resolution Peripheral Quantitative Computed Tomography. J Bone Miner Res. 2023 09; 38(9):1234-1244.
A Fracture Risk Assessment Tool for High Resolution Peripheral Quantitative Computed Tomography.
Bozzini BN, Nguyen VT, Reynoso MC, Guerriere KI, Walker LA, Taylor KM, Foulis SA, Bouxsein ML, Hughes JM, Popp KL
The Risk of Menstrual Dysfunction Increases for Women during U.S. Army Basic Combat Training. Med Sci Sports Exerc. 2023 09 01; 55(9):1533-1539.
The Risk of Menstrual Dysfunction Increases for Women during U.S. Army Basic Combat Training.
Bredella MA, Patel KA, Leyne M, Levy AS, Tannous BA, Bouxsein ML
The Journal of continuing education in the health professions
Design and Implementation of a Leadership Development Program for Early-Stage Investigators: Initial Results. J Contin Educ Health Prof. 2023 Jun 28.
Design and Implementation of a Leadership Development Program for Early-Stage Investigators: Initial Results.
Allaire BT, Mousavi SJ, James JN, Bouxsein ML, Anderson DE
Dependence of trunk muscle size and position on age, height, and weight in a multi-ethnic cohort of middle-aged and older men and women. J Biomech. 2023 08; 157:111710.
Dependence of trunk muscle size and position on age, height, and weight in a multi-ethnic cohort of middle-aged and older men and women.
Kaur S, Nimmala S, Singhal V, Mitchell DM, Pedreira CC, Lauze M, Lee H, Stanford FC, Bouxsein ML, Bredella MA, Misra M
Bone changes post-sleeve gastrectomy in relation to body mass and hormonal changes. Eur J Endocrinol. 2023 Sep 01; 189(3):346-354.
Bone changes post-sleeve gastrectomy in relation to body mass and hormonal changes.
Long T, Outerleys J, Yeung T, Fernandez J, Bouxsein ML, Davis IS, Bredella MA, Besier TF
Computer methods in biomechanics and biomedical engineering
Predicting ankle and knee sagittal kinematics and kinetics using an ankle-mounted inertial sensor. Comput Methods Biomech Biomed Engin. 2024 Jul; 27(9):1057-1070.
Predicting ankle and knee sagittal kinematics and kinetics using an ankle-mounted inertial sensor.
Tonnesen PE, Mercaldo ND, Tahir I, Dietrich AW, Amayri W, Graur A, Allaire B, Bouxsein ML, Samelson EJ, Kiel DP, Fintelmann FJ
Muscle Reference Values From Thoracic and Abdominal CT for Sarcopenia Assessment: The Framingham Heart Study. Invest Radiol. 2024 Mar 01; 59(3):259-270.
Muscle Reference Values From Thoracic and Abdominal CT for Sarcopenia Assessment: The Framingham Heart Study.
Coulombe JC, Maridas DE, Chow JL, Bouxsein ML
Small animal DXA instrument comparison and validation. Bone. 2024 01; 178:116923.
Small animal DXA instrument comparison and validation.
Yan C, Lynch AC, Alemi MM, Banks JJ, Bouxsein ML, Anderson DE
Validity of evaluating spinal kinetics without participant-specific kinematics. J Biomech. 2023 12; 161:111821.
Validity of evaluating spinal kinetics without participant-specific kinematics.
Okoro PC, Orwoll ES, Huttenhower C, Morgan X, Kuntz TM, McIver LJ, Dufour AB, Bouxsein ML, Langsetmo L, Farsijani S, Kado DM, Pacifici R, Sahni S, Kiel DP
A two-cohort study on the association between the gut microbiota and bone density, microarchitecture, and strength. Front Endocrinol (Lausanne). 2023; 14:1237727.
A two-cohort study on the association between the gut microbiota and bone density, microarchitecture, and strength.
Mitchell DM, Singhal V, Nimmala S, Lauze M, Bouxsein ML, Misra M, Bredella MA
Risk of wrist fracture, estimated by the load-to-strength ratio, declines following sleeve gastrectomy in adolescents and young adults. Osteoporos Int. 2024 Feb; 35(2):285-291.
Risk of wrist fracture, estimated by the load-to-strength ratio, declines following sleeve gastrectomy in adolescents and young adults.
Lv Z, Zhang J, Liang S, Zhou C, Hu D, Brooks DJ, Bouxsein ML, Lanske B, Kostenuik P, Gori F, Baron R
Comparative study in estrogen-depleted mice identifies skeletal and osteocyte transcriptomic responses to abaloparatide and teriparatide. JCI Insight. 2023 10 23; 8(20).
Comparative study in estrogen-depleted mice identifies skeletal and osteocyte transcriptomic responses to abaloparatide and teriparatide.
Draghici AE, Zahedi B, Taylor JA, Bouxsein ML, Yu EW
Frontiers in clinical diabetes and healthcare
Vascular deficits contributing to skeletal fragility in type 1 diabetes. Front Clin Diabetes Healthc. 2023; 4:1272804.
Vascular deficits contributing to skeletal fragility in type 1 diabetes.
Saunders RK, Kilroe KM, Joseph TV, Caksa S, Bouxsein ML, Misra M, Mitchell DM
Total Calcium Intake Is Associated With Trabecular Bone Density in Adolescent Girls With Type 1 Diabetes. JBMR Plus. 2023 Nov; 7(11):e10813.
Total Calcium Intake Is Associated With Trabecular Bone Density in Adolescent Girls With Type 1 Diabetes.
Coulombe JC, Johannesdottir F, Burkhart KA, Brummer H, Allaire BT, Bouxsein ML
Changes in Vertebral Bone Density and Paraspinal Muscle Morphology Following Spaceflight and 1?Year Readaptation on Earth. JBMR Plus. 2023 Dec; 7(12):e10810.
Changes in Vertebral Bone Density and Paraspinal Muscle Morphology Following Spaceflight and 1?Year Readaptation on Earth.
Enhancing Professional Success in the Bone, Mineral, and Musculoskeletal Field.
Sex differences in muscle health in simulated micro- and partial-gravity environments in rats. Sports Med Health Sci. 2023 Dec; 5(4):319-328.
Sex differences in muscle health in simulated micro- and partial-gravity environments in rats.
Valderrábano RJ, Pencina K, Shang YV, Echevarria E, Dixon R, Ghattas C, Wilson L, Reid KF, Storer T, Garrahan M, Tedtsen T, Zafonte R, Bouxsein M, Bhasin S
Bone microarchitectural alterations associated with spinal cord injury: Relation to sex hormones, metabolic factors, and loading. Bone. 2024 04; 181:117039.
Bone microarchitectural alterations associated with spinal cord injury: Relation to sex hormones, metabolic factors, and loading.
Issertine M, Rosa-Calwell ME, Sung DM, Bouxsein ML, Rutkove SB, Mortreux M
Adaptation to full weight-bearing following disuse in rats: The impact of biological sex on musculoskeletal recovery. Physiol Rep. 2024 Feb; 12(4):e15938.
Adaptation to full weight-bearing following disuse in rats: The impact of biological sex on musculoskeletal recovery.
Emerzian SR, Johannesdottir F, Yu EW, Bouxsein ML
Use of noninvasive imaging to identify causes of skeletal fragility in adults with diabetes: a review. JBMR Plus. 2024 Feb; 8(2):ziae003.
Use of noninvasive imaging to identify causes of skeletal fragility in adults with diabetes: a review.
Szulc P, Dufour AB, Hannan MT, Kiel DP, Chapurlat R, Sornay-Rendu E, Merle B, Boyd SK, Whittier DE, Hanley DA, Goltzman D, Wong AKO, Lespessailles E, Khosla S, Ferrari S, Biver E, Bouxsein ML, Samelson EJ
Fracture risk based on high-resolution peripheral quantitative computed tomography measures does not vary with age in older adults-the bone microarchitecture international consortium prospective cohort study. J Bone Miner Res. 2024 May 24; 39(5):561-570.
Fracture risk based on high-resolution peripheral quantitative computed tomography measures does not vary with age in older adults-the bone microarchitecture international consortium prospective cohort study.
Schini M, Vilaca T, Vittinghoff E, Lui LY, Ewing SK, Thompson AR, Bauer DC, Bouxsein ML, Black DM, Eastell R
Influence of age on the efficacy of pharmacologic treatments on fracture risk reduction and increases in BMD: RCT results from the FNIH-ASBMR-SABRE project. J Bone Miner Res. 2024 May 24; 39(5):544-550.
Influence of age on the efficacy of pharmacologic treatments on fracture risk reduction and increases in BMD: RCT results from the FNIH-ASBMR-SABRE project.
Usiskin IM, Mitchell GF, Bouxsein ML, Liu CT, Kiel DP, Samelson EJ
Vascular function and skeletal fragility: a study of tonometry, brachial hemodynamics, and bone microarchitecture. J Bone Miner Res. 2024 Aug 05; 39(7):906-917.
Vascular function and skeletal fragility: a study of tonometry, brachial hemodynamics, and bone microarchitecture.
Tenforde AS, Ackerman KE, Bouxsein ML, Gaudette L, McCall L, Rudolph SE, Gehman S, Garrahan M, Hughes JM, Outerleys J, Davis IS, Popp KL
Factors Associated With High-Risk and Low-Risk Bone Stress Injury in Female Runners: Implications for Risk Factor Stratification and Management. Orthop J Sports Med. 2024 May; 12(5):23259671241246227.
Factors Associated With High-Risk and Low-Risk Bone Stress Injury in Female Runners: Implications for Risk Factor Stratification and Management.
Schini M, Vilaca T, Lui LY, Ewing SK, Thompson A, Vittinghoff E, Bauer DC, Bouxsein ML, Black DM, Eastell R
Pre-treatment bone mineral density and the benefit of pharmacologic treatment on fracture risk and BMD change: analysis from the FNIH-ASBMR SABRE project. J Bone Miner Res. 2024 Aug 05; 39(7):867-876.
Pre-treatment bone mineral density and the benefit of pharmacologic treatment on fracture risk and BMD change: analysis from the FNIH-ASBMR SABRE project.
Black DM, Thompson AR, Eastell R, Bouxsein ML
Bone mineral density as a surrogate endpoint for fracture risk reduction in clinical trials of osteoporosis therapies: an update on SABRE. Lancet Diabetes Endocrinol. 2024 Jun; 12(6):371-373.
Bone mineral density as a surrogate endpoint for fracture risk reduction in clinical trials of osteoporosis therapies: an update on SABRE.
Jung Y, Ay B, Cyr SM, Tognoni CM, Klovdahl K, Matthias J, Cui Q, Brooks DJ, Bouxsein ML, Carreras I, Dedeoglu A, Bastepe M
Amyloid-ß neuropathology induces bone loss in male mice by suppressing bone formation and enhancing bone resorption. Bone Rep. 2024 Jun; 21:101771.
Amyloid-ß neuropathology induces bone loss in male mice by suppressing bone formation and enhancing bone resorption.
Keaveny TM, Adams AL, Orwoll ES, Khosla S, Siris ES, McClung MR, Bouxsein ML, Fatemi S, Lee DC, Kopperdahl DL
Osteoporosis treatment prevents hip fracture similarly in both sexes: the FOCUS observational study. J Bone Miner Res. 2024 Sep 26; 39(10):1424-1433.
Osteoporosis treatment prevents hip fracture similarly in both sexes: the FOCUS observational study.
Faraj M, Schwartz AV, Burghardt AJ, Black D, Orwoll E, Strotmeyer ES, Vittinghoff E, Fogolari M, Angeletti S, Banfi G, Lombardi G, Woods G, Lui LY, Bouxsein M, Napoli N
Risk Factors for Bone Microarchitecture Impairments in Older Men With Type 2 Diabetes-The MrOS Study. J Clin Endocrinol Metab. 2025 Apr 22; 110(5):e1660-e1669.
Risk Factors for Bone Microarchitecture Impairments in Older Men With Type 2 Diabetes-The MrOS Study.
Shen I, Usala RL, Mohseni M, Bouxsein ML, Mitchell DM, Scheller EL
Adolescent Girls With Type 1 Diabetes Develop Changes in Bone Prior to Evidence of Clinical Neuropathy. J Clin Endocrinol Metab. 2025 Apr 22; 110(5):e1555-e1565.
Adolescent Girls With Type 1 Diabetes Develop Changes in Bone Prior to Evidence of Clinical Neuropathy.
Popp KL, Bozzini BN, Reynoso M, Coulombe J, Guerriere KI, Proctor SP, Castellani CM, Walker LA, Zurinaga N, Kuhn K, Foulis SA, Bouxsein ML, Hughes JM, Santoro N
Hypothalamic-pituitary-ovarian axis suppression is common among women during US Army Basic Combat Training. Br J Sports Med. 2024 Sep 09; 58(18):1052-1060.
Hypothalamic-pituitary-ovarian axis suppression is common among women during US Army Basic Combat Training.
Marquardt JP, Tonnesen PE, Mercaldo ND, Graur A, Allaire B, Bouxsein ML, Samelson EJ, Kiel DP, Fintelmann FJ
Subcutaneous and Visceral Adipose Tissue Reference Values From the Framingham Heart Study Thoracic and Abdominal CT. Invest Radiol. 2025 Feb 01; 60(2):95-104.
Subcutaneous and Visceral Adipose Tissue Reference Values From the Framingham Heart Study Thoracic and Abdominal CT.
Vilaca T, Schini M, Lui LY, Ewing SK, Thompson AR, Vittinghoff E, Bauer DC, Eastell R, Black DM, Bouxsein ML
The relationship between treatment-related changes in total hip BMD measured after 12, 18, and 24 mo and fracture risk reduction in osteoporosis clinical trials: the FNIH-ASBMR-SABRE project. J Bone Miner Res. 2024 Sep 26; 39(10):1434-1442.
The relationship between treatment-related changes in total hip BMD measured after 12, 18, and 24 mo and fracture risk reduction in osteoporosis clinical trials: the FNIH-ASBMR-SABRE project.
Johannesdottir F, Tedtsen T, Cooke LM, Mahar S, Zhang M, Nustad J, Garrahan MA, Gehman SE, Yu EW, Bouxsein ML
Microvascular disease and early diabetes onset are associated with deficits in femoral neck bone density and structure among older adults with longstanding type 1 diabetes. J Bone Miner Res. 2024 Sep 26; 39(10):1454-1463.
Microvascular disease and early diabetes onset are associated with deficits in femoral neck bone density and structure among older adults with longstanding type 1 diabetes.
Coulombe JC, Bozzini BN, Guerriere KI, Foulis SA, Reynoso M, Walker LA, Staab JS, Bouxsein ML, Hughes JM, Popp KL
Association between changes in serum bone metabolism markers and bone microarchitecture changes during basic combat training - The ARMI study. Bone. 2024 Dec; 189:117241.
Association between changes in serum bone metabolism markers and bone microarchitecture changes during basic combat training - The ARMI study.
Sarfati M, Chapurlat R, Dufour AB, Sornay-Rendu E, Merle B, Boyd SK, Whittier DE, Hanley DA, Goltzman D, Szulc P, Wong AKO, Lespessailles E, Khosla S, Ferrari S, Biver E, Ohlsson C, Lorentzon M, Mellström D, Nethander M, Samelson EJ, Kiel DP, Hannan MT, Bouxsein ML
Short-term risk of fracture is increased by deficits in cortical and trabecular bone microarchitecture independent of DXA BMD and FRAX: Bone Microarchitecture International Consortium (BoMIC) prospective cohorts. J Bone Miner Res. 2024 Oct 29; 39(11):1574-1583.
Short-term risk of fracture is increased by deficits in cortical and trabecular bone microarchitecture independent of DXA BMD and FRAX: Bone Microarchitecture International Consortium (BoMIC) prospective cohorts.
Bernhard JM, Edgcomb VP, Visscher PT, McIntyre-Wressnig A, Summons RE, Bouxsein ML, Louis L, Jeglinski M
Insights into foraminiferal influences on microfabrics of microbialites at Highborne Cay, Bahamas. Proc Natl Acad Sci U S A. 2013 Jun 11; 110(24):9830-4.
Insights into foraminiferal influences on microfabrics of microbialites at Highborne Cay, Bahamas.
Roux JP, Wegrzyn J, Boutroy S, Bouxsein ML, Hans D, Chapurlat R
The predictive value of trabecular bone score (TBS) on whole lumbar vertebrae mechanics: an ex vivo study. Osteoporos Int. 2013 Sep; 24(9):2455-60.
The predictive value of trabecular bone score (TBS) on whole lumbar vertebrae mechanics: an ex vivo study.
Kacena MA, Gundberg CM, Kacena WJ, Landis WJ, Boskey AL, Bouxsein ML, Horowitz MC
The effects of GATA-1 and NF-E2 deficiency on bone biomechanical, biochemical, and mineral properties. J Cell Physiol. 2013 Jul; 228(7):1594-600.
The effects of GATA-1 and NF-E2 deficiency on bone biomechanical, biochemical, and mineral properties.
Barnet IR, Emerzian SR, Behzad R, Brooks DJ, Tedtsen T, Granados M, Park S, Moore J, Olson JD, Karim L, Bouxsein ML, Cline JM, Willey JS
Total body irradiation is associated with long-term deficits in femoral bone structure but not mechanical properties in male rhesus macaques. Sci Rep. 2024 10 08; 14(1):23379.
Total body irradiation is associated with long-term deficits in femoral bone structure but not mechanical properties in male rhesus macaques.
Ye C, Leslie WD, Bouxsein ML, Dufour AB, Guermazi A, Habtemariam D, Jarraya M, Kiel DP, Suri P, Samelson EJ
Association of vertebral fractures with worsening degenerative changes of the spine: a longitudinal study. J Bone Miner Res. 2024 Nov 29; 39(12):1744-1751.
Association of vertebral fractures with worsening degenerative changes of the spine: a longitudinal study.
Corrigendum to "Small animal DXA instrument comparison and validation" [Bone 178 (2024) p 1-7, 116923]. Bone. 2025 Jan; 190:117298.
Corrigendum to "Small animal DXA instrument comparison and validation" [Bone 178 (2024) p 1-7, 116923].
Kremsky I, Pergerson R, Justinen S, Stanbouly S, Willey J, Fuller CA, Takahashi S, Vitaterna MH, Bouxsein M, Mao X
International journal of molecular sciences
Artificial Gravity Attenuates the Transcriptomic Response to Spaceflight in the Optic Nerve and Retina. Int J Mol Sci. 2024 Nov 09; 25(22).
Artificial Gravity Attenuates the Transcriptomic Response to Spaceflight in the Optic Nerve and Retina.
Correction: Irisin directly stimulates osteoclastogenesis and bone resorption in vitro and in vivo. Elife. 2024 Nov 11; 13.
Correction: Irisin directly stimulates osteoclastogenesis and bone resorption in vitro and in vivo.
Emerzian SR, Chow J, Behzad R, Unal M, Brooks DJ, Wu IH, Gauthier J, Jangolla SVT, Yu MG, Shah HS, King GL, Johannesdottir F, Karim L, Yu EW, Bouxsein ML
Long-duration type 1 diabetes is associated with deficient cortical bone mechanical behavior and altered matrix composition in human femoral bone. J Bone Miner Res. 2024 Dec 31; 40(1):87-99.
Long-duration type 1 diabetes is associated with deficient cortical bone mechanical behavior and altered matrix composition in human femoral bone.
Anderson DE, Demissie S, Allaire BT, Bruno AG, Kopperdahl DL, Keaveny TM, Kiel DP, Bouxsein ML
The associations between QCT-based vertebral bone measurements and prevalent vertebral fractures depend on the spinal locations of both bone measurement and fracture. Osteoporos Int. 2014 Feb; 25(2):559-66.
The associations between QCT-based vertebral bone measurements and prevalent vertebral fractures depend on the spinal locations of both bone measurement and fracture.
Romanowicz GE, Popp K, Dinh E, Harker IR, Leguineche K, Hughes JM, Ackerman KE, Bouxsein ML, Guldberg RE
medRxiv : the preprint server for health sciences
Deciphering Risk of Recurrent Bone Stress Injury in Female Runners Using Serum Proteomics Analysis and Predictive Models. medRxiv. 2024 Dec 05.
Deciphering Risk of Recurrent Bone Stress Injury in Female Runners Using Serum Proteomics Analysis and Predictive Models.
Schini M, Lui LY, Vilaca T, Ewing SK, Thompson A, Bauer DC, Bouxsein ML, Black DM, Eastell R
The relationship between baseline bone mineral density and fracture incidence in the placebo groups of randomized controlled trials using individual patient data from the FNIH-ASBMR-SABRE project. J Bone Miner Res. 2025 Mar 15; 40(3):307-314.
The relationship between baseline bone mineral density and fracture incidence in the placebo groups of randomized controlled trials using individual patient data from the FNIH-ASBMR-SABRE project.
Mao XW, Pecaut MJ, Stodieck LS, Ferguson VL, Bateman TA, Bouxsein M, Jones TA, Moldovan M, Cunningham CE, Chieu J, Gridley DS
Spaceflight environment induces mitochondrial oxidative damage in ocular tissue. Radiat Res. 2013 Oct; 180(4):340-50.
Spaceflight environment induces mitochondrial oxidative damage in ocular tissue.
Load-to-strength ratio as an estimate of wrist facture after gastric bypass vs gastric banding. JBMR Plus. 2025 Mar; 9(3):ziae175.
Load-to-strength ratio as an estimate of wrist facture after gastric bypass vs gastric banding.
Lewiecki EM, Adler RA, Bilezikian JP, Bouxsein ML, Marcus R, McClung MR, Miller PD, Tanner SB, Randall S
Osteoporosis update from the 2012 Santa Fe Bone Symposium. J Clin Densitom. 2013 Oct-Dec; 16(4):584-600.
Osteoporosis update from the 2012 Santa Fe Bone Symposium.
Allaire BT, Johannesdottir F, Bouxsein ML, Anderson DE
Physiological and Anthropometric Factors Associated With Spine Loading Estimates From Imaging-Based Subject-Specific Musculoskeletal Models. JOR Spine. 2025 Jun; 8(2):e70059.
Physiological and Anthropometric Factors Associated With Spine Loading Estimates From Imaging-Based Subject-Specific Musculoskeletal Models.
Höppner J, Noda H, Anitha AK, Cheloha RW, Dean T, Bruce M, Brooks DJ, Mannstadt M, Bouxsein ML, Gellman SH, Khatri A, Jüppner H, Gardella TJ
Prolonging parathyroid hormone analog action in vitro and in vivo through peptide lipidation. Nat Commun. 2025 May 14; 16(1):4487.
Prolonging parathyroid hormone analog action in vitro and in vivo through peptide lipidation.
Beyond BMD and FRAX: potential for improving hip fracture prediction with bone microstructure measures. J Bone Miner Res. 2026 Feb 03; 41(2):100-101.
Beyond BMD and FRAX: potential for improving hip fracture prediction with bone microstructure measures.
Sung M, Li J, Spieker AJ, Spatz J, Ellman R, Ferguson VL, Bateman TA, Rosen GD, Bouxsein M, Rutkove SB
Journal of musculoskeletal & neuronal interactions
Spaceflight and hind limb unloading induce similar changes in electrical impedance characteristics of mouse gastrocnemius muscle. J Musculoskelet Neuronal Interact. 2013 Dec; 13(4):405-11.
Spaceflight and hind limb unloading induce similar changes in electrical impedance characteristics of mouse gastrocnemius muscle.
Nawathe S, Akhlaghpour H, Bouxsein ML, Keaveny TM
Microstructural failure mechanisms in the human proximal femur for sideways fall loading. J Bone Miner Res. 2014 Feb; 29(2):507-15.
Microstructural failure mechanisms in the human proximal femur for sideways fall loading.
Emerzian SR, Hanlon J, Behzad R, Unal M, Brooks DJ, Wu IH, Gauthier J, Jangolla S, Yu MG, Shah HS, King GL, Johannesdottir F, Karim L, Yu EW, Bouxsein ML
Effect of type 1 and type 2 diabetes on human femoral trabecular bone composition, microarchitecture, and mechanical behavior. Bone. 2025 Nov; 200:117588.
Effect of type 1 and type 2 diabetes on human femoral trabecular bone composition, microarchitecture, and mechanical behavior.
Fazeli PK, Wang IS, Miller KK, Herzog DB, Misra M, Lee H, Finkelstein JS, Bouxsein ML, Klibanski A
Teriparatide increases bone formation and bone mineral density in adult women with anorexia nervosa. J Clin Endocrinol Metab. 2014 Apr; 99(4):1322-9.
Teriparatide increases bone formation and bone mineral density in adult women with anorexia nervosa.
Johannesdottir F, Aspelund T, Mahar S, Sigurdsson S, Gudnason V, Bouxsein ML
The relationship between fall risk, trochanteric soft tissue thickness, and hip fracture risk in older adults. J Bone Miner Res. 2025 Oct 31.
The relationship between fall risk, trochanteric soft tissue thickness, and hip fracture risk in older adults.
Bruno AG, Broe KE, Zhang X, Samelson EJ, Meng CA, Manoharan R, D'Agostino J, Cupples LA, Kiel DP, Bouxsein ML
Vertebral size, bone density, and strength in men and women matched for age and areal spine BMD. J Bone Miner Res. 2014 Mar; 29(3):562-9.
Vertebral size, bone density, and strength in men and women matched for age and areal spine BMD.
Zhu ED, Louis L, Brooks DJ, Bouxsein ML, Demay MB
Effect of bisphosphonates on the rapidly growing male murine skeleton. Endocrinology. 2014 Apr; 155(4):1188-96.
Effect of bisphosphonates on the rapidly growing male murine skeleton.
Ellman R, Grasso DJ, van Vliet M, Brooks DJ, Spatz JM, Conlon C, Bouxsein ML
Combined effects of botulinum toxin injection and hind limb unloading on bone and muscle. Calcif Tissue Int. 2014 Mar; 94(3):327-37.
Combined effects of botulinum toxin injection and hind limb unloading on bone and muscle.
Yu EW, Bouxsein ML, Roy AE, Baldwin C, Cange A, Neer RM, Kaplan LM, Finkelstein JS
Bone loss after bariatric surgery: discordant results between DXA and QCT bone density. J Bone Miner Res. 2014 Mar; 29(3):542-50.
Bone loss after bariatric surgery: discordant results between DXA and QCT bone density.
Erratum to: The factor-of-risk biomechanical approach predicts hip fracture in men and women: the Framingham Study. Osteoporos Int. 2014 May; 25(5):1657.
Erratum to: The factor-of-risk biomechanical approach predicts hip fracture in men and women: the Framingham Study.
Zhao JJ, Lin J, Zhu D, Wang X, Brooks D, Chen M, Chu ZB, Takada K, Ciccarelli B, Admin S, Tao J, Tai YT, Treon S, Pinkus G, Kuo WP, Hideshima T, Bouxsein M, Munshi N, Anderson K, Carrasco R
miR-30-5p functions as a tumor suppressor and novel therapeutic tool by targeting the oncogenic Wnt/ß-catenin/BCL9 pathway. Cancer Res. 2014 Mar 15; 74(6):1801-13.
miR-30-5p functions as a tumor suppressor and novel therapeutic tool by targeting the oncogenic Wnt/ß-catenin/BCL9 pathway.
Fajardo RJ, Karim L, Calley VI, Bouxsein ML
A review of rodent models of type 2 diabetic skeletal fragility. J Bone Miner Res. 2014; 29(5):1025-40.
A review of rodent models of type 2 diabetic skeletal fragility.
Anderson DE, Keko M, James J, Allaire BT, Kozono D, Doyle PF, Kang H, Caplan S, Balboni T, Spektor A, Huynh MA, Bouxsein ML, Hackney DB, Alkalay RN
Metastatic Spine Disease Alters Vertebral Load-To-Strength Ratios in Cancer Patients Compared to Healthy Individuals. JOR Spine. 2026 Mar; 9(1):e70111.
Metastatic Spine Disease Alters Vertebral Load-To-Strength Ratios in Cancer Patients Compared to Healthy Individuals.
Singhal V, Lawson EA, Ackerman KE, Fazeli PK, Clarke H, Lee H, Eddy K, Marengi DA, Derrico NP, Bouxsein ML, Misra M
Irisin levels are lower in young amenorrheic athletes compared with eumenorrheic athletes and non-athletes and are associated with bone density and strength estimates. PLoS One. 2014; 9(6):e100218.
Irisin levels are lower in young amenorrheic athletes compared with eumenorrheic athletes and non-athletes and are associated with bone density and strength estimates.
Anderson DE, Bean JF, Holt NE, Keel JC, Bouxsein ML
American journal of physical medicine & rehabilitation
Computed tomography-based muscle attenuation and electrical impedance myography as indicators of trunk muscle strength independent of muscle size in older adults. Am J Phys Med Rehabil. 2014 Jul; 93(7):553-61.
Computed tomography-based muscle attenuation and electrical impedance myography as indicators of trunk muscle strength independent of muscle size in older adults.
Gaudette LW, Ackerman KE, Bouxsein ML, Bruneau MM, de Souza Junior JR, Garrahan M, Gehman S, Hughes JM, Outerleys J, Willy RW, Davis IS, Popp KL, Tenforde AS
Biomechanics associated with bone stress injury in athletes differ by proximal and distal anatomical locations: a cross-sectional analysis. BMJ Open Sport Exerc Med. 2025; 11(2):e002469.
Biomechanics associated with bone stress injury in athletes differ by proximal and distal anatomical locations: a cross-sectional analysis.
A Review on Osteoporosis. JAMA. 2025 Nov 25; 334(20):1853-1854.
Foulis SA, Proctor SP, Spiering BA, Walker LA, Guerriere Aaron K, Castellani CM, Hussian IM, Heaton KJ, Bouxsein ML, Gaffney-Stomberg E, Fraley AL, Popp KL, Davis IS, Staab JS, Staab JE, Judkins JL, Merkle SL, Ritland BM, Matheny RW, Hauret KG, Canham-Chervak M, McClung JP, Jones BH, Friedl KE, Hughes JM, Taylor KM
Model for Musculoskeletal Injury Risk Factors Among US Army Basic Combat Trainees. JAMA Netw Open. 2025 06 02; 8(6):e2513177.
Model for Musculoskeletal Injury Risk Factors Among US Army Basic Combat Trainees.
Keaveny TM, Adams AL, Orwoll ES, Khosla S, McClung MR, Bouxsein ML, Fatemi S, Besler BA, Lee DC, Kopperdahl DL
Improved Prediction of Hip Fracture Using Multi-Faceted Biomechanical Computed Tomography. J Bone Miner Res. 2025 Oct 04.
Improved Prediction of Hip Fracture Using Multi-Faceted Biomechanical Computed Tomography.
Lizotte T, Lajoie C, Porter S, Lang S, Vesper FA, Brooks DJ, Gartner C, Alexander MS, Vary C, Bouxsein ML, Becker KA
bioRxiv : the preprint server for biology
Deletion of Dock7 Exons 3 and 4 Results in Reduced Trabecular Microarchitecture and a Decrease in Mineralization. bioRxiv. 2026 Jan 02.
Deletion of Dock7 Exons 3 and 4 Results in Reduced Trabecular Microarchitecture and a Decrease in Mineralization.
Response to Letter to the Editor Regarding "The relationship between treatment-related changes in total hip BMD measured after 12, 18, and 24 mo and fracture risk reduction in osteoporosis clinical trials: the FNIH-ASBMR-SABER project". J Bone Miner Res. 2026 Jan 19.
Response to Letter to the Editor Regarding "The relationship between treatment-related changes in total hip BMD measured after 12, 18, and 24 mo and fracture risk reduction in osteoporosis clinical trials: the FNIH-ASBMR-SABER project".
Bugbird AR, Burghardt AJ, Langsetmo L, Ensrud KE, Bouxsein ML, Kiel DP, Boyd SK, Whittier DE
External validation of a novel HR-pQCT based fracture risk assessment tool (FRAC) in a Male Cohort: The Osteoporotic Fractures in Men (MrOS) Study. J Bone Miner Res. 2025 Dec 31.
External validation of a novel HR-pQCT based fracture risk assessment tool (FRAC) in a Male Cohort: The Osteoporotic Fractures in Men (MrOS) Study.
Wang JS, Strauss K, Houghton C, Islam N, Yoon SH, Kobayashi T, Brooks DJ, Bouxsein ML, Zhao Y, Yee CS, Alliston TN, Wein MN
Osteoclast-independent osteocyte dendrite defects in mice bearing the osteogenesis imperfecta-causing Sp7 R342C mutation. Bone Res. 2025 Jul 19; 13(1):70.
Osteoclast-independent osteocyte dendrite defects in mice bearing the osteogenesis imperfecta-causing Sp7 R342C mutation.
Thuere KL, Mantz L, Sultana S, Henderson LM, Sakoda LC, Kazerooni E, Estépar RSJ, Bouxsein ML, Fintelmann FJ
Opportunistic Screening on Chest CT, From the AJR Special Series on Screening. AJR Am J Roentgenol. 2026 Apr 08; 1-18.
Opportunistic Screening on Chest CT, From the AJR Special Series on Screening.
Heilmann NZ, Freeland KS, Yu T, Caserotti P, Burghardt AJ, Knueven MW, Nindl BC, Ruppert KM, Stefanick ML, Bouxsein ML, Lane NE, Cauley JA, Strotmeyer ES
Associations of Muscle Strength and Functional Power with Longitudinal Change in HR-pQCT Bone Parameters: The Osteoporotic Fractures in Men (MrOS) Study. J Bone Miner Res. 2025 Dec 18.
Associations of Muscle Strength and Functional Power with Longitudinal Change in HR-pQCT Bone Parameters: The Osteoporotic Fractures in Men (MrOS) Study.
Cooke LM, Garrahan MA, Gehman S, Tedtsen TA, Smith NI, Coulombe J, Bouxsein ML
Effect of increased soft tissue thickness on bone density and microstructure measurements using the 2nd generation HR-pQCT scanner. Bone. 2026 May; 206:117831.
Effect of increased soft tissue thickness on bone density and microstructure measurements using the 2nd generation HR-pQCT scanner.
Emerzian SR, Johannesdottir F, Lee DC, Wu IH, Jangolla SVT, Yu MG, Shah HS, King GL, Keaveny TM, Engelke K, Yu EW, Bouxsein ML
Femora from adults with type 1 or type 2 diabetes have lower bone strength and smaller hip geometry. JBMR Plus. 2026 Mar; 10(3):ziaf127.
Femora from adults with type 1 or type 2 diabetes have lower bone strength and smaller hip geometry.
Amorim T, David NL, Moturi S, Turnquist LR, Holmes TM, Bouxsein ML, Fazeli PK
Effects of teriparatide on hip structure and bone microarchitecture in women with anorexia nervosa: a placebo-controlled randomized trial. Osteoporos Int. 2026 Mar; 37(3):749-758.
Effects of teriparatide on hip structure and bone microarchitecture in women with anorexia nervosa: a placebo-controlled randomized trial.
Mao XW, Pecaut MJ, Stodieck LS, Ferguson VL, Bateman TA, Bouxsein ML, Gridley DS
Biological and metabolic response in STS-135 space-flown mouse skin. Free Radic Res. 2014 Aug; 48(8):890-7.
Biological and metabolic response in STS-135 space-flown mouse skin.
Putman MS, Milliren CE, Derrico N, Uluer A, Sicilian L, Lapey A, Sawicki G, Gordon CM, Bouxsein ML, Finkelstein JS
Compromised bone microarchitecture and estimated bone strength in young adults with cystic fibrosis. J Clin Endocrinol Metab. 2014 Sep; 99(9):3399-407.
Compromised bone microarchitecture and estimated bone strength in young adults with cystic fibrosis.
Devlin MJ, Van Vliet M, Motyl K, Karim L, Brooks DJ, Louis L, Conlon C, Rosen CJ, Bouxsein ML
Early-onset type 2 diabetes impairs skeletal acquisition in the male TALLYHO/JngJ mouse. Endocrinology. 2014 Oct; 155(10):3806-16.
Early-onset type 2 diabetes impairs skeletal acquisition in the male TALLYHO/JngJ mouse.
Lai LP, Lotinun S, Bouxsein ML, Baron R, McMahon AP
Stk11 (Lkb1) deletion in the osteoblast lineage leads to high bone turnover, increased trabecular bone density and cortical porosity. Bone. 2014 Dec; 69:98-108.
Stk11 (Lkb1) deletion in the osteoblast lineage leads to high bone turnover, increased trabecular bone density and cortical porosity.
Araujo AB, Yang M, Suarez EA, Dagincourt N, Abraham JR, Chiu G, Holick MF, Bouxsein ML, Zmuda JM
Racial/ethnic and socioeconomic differences in bone loss among men. J Bone Miner Res. 2014 Dec; 29(12):2552-60.
Racial/ethnic and socioeconomic differences in bone loss among men.
Li J, Jafarpoor M, Bouxsein M, Rutkove SB
Distinguishing neuromuscular disorders based on the passive electrical material properties of muscle. Muscle Nerve. 2015 Jan; 51(1):49-55.
Distinguishing neuromuscular disorders based on the passive electrical material properties of muscle.
Tsai JN, Uihlein AV, Burnett-Bowie SA, Neer RM, Zhu Y, Derrico N, Lee H, Bouxsein ML, Leder BZ
Comparative effects of teriparatide, denosumab, and combination therapy on peripheral compartmental bone density, microarchitecture, and estimated strength: the DATA-HRpQCT Study. J Bone Miner Res. 2015 Jan; 30(1):39-45.
Comparative effects of teriparatide, denosumab, and combination therapy on peripheral compartmental bone density, microarchitecture, and estimated strength: the DATA-HRpQCT Study.
Response letter to the editor. J Clin Endocrinol Metab. 2015 Jan; 100(1):L9-L10.
Yu EW, Putman MS, Derrico N, Abrishamanian-Garcia G, Finkelstein JS, Bouxsein ML
Defects in cortical microarchitecture among African-American women with type 2 diabetes. Osteoporos Int. 2015 Feb; 26(2):673-9.
Defects in cortical microarchitecture among African-American women with type 2 diabetes.
Fazeli PK, Faje AT, Cross EJ, Lee H, Rosen CJ, Bouxsein ML, Klibanski A
Serum FGF-21 levels are associated with worsened radial trabecular bone microarchitecture and decreased radial bone strength in women with anorexia nervosa. Bone. 2015 Aug; 77:6-11.
Serum FGF-21 levels are associated with worsened radial trabecular bone microarchitecture and decreased radial bone strength in women with anorexia nervosa.
Wein MN, Spatz J, Nishimori S, Doench J, Root D, Babij P, Nagano K, Baron R, Brooks D, Bouxsein M, Pajevic PD, Kronenberg HM
HDAC5 controls MEF2C-driven sclerostin expression in osteocytes. J Bone Miner Res. 2015 Mar; 30(3):400-11.
HDAC5 controls MEF2C-driven sclerostin expression in osteocytes.
Nawathe S, Nguyen BP, Barzanian N, Akhlaghpour H, Bouxsein ML, Keaveny TM
Cortical and trabecular load sharing in the human femoral neck. J Biomech. 2015 Mar 18; 48(5):816-22.
Cortical and trabecular load sharing in the human femoral neck.
Development and Validation of a Musculoskeletal Model of the Fully Articulated Thoracolumbar Spine and Rib Cage. J Biomech Eng. 2015 Aug; 137(8):081003.
Development and Validation of a Musculoskeletal Model of the Fully Articulated Thoracolumbar Spine and Rib Cage.
Nawathe S, Yang H, Fields AJ, Bouxsein ML, Keaveny TM
Theoretical effects of fully ductile versus fully brittle behaviors of bone tissue on the strength of the human proximal femur and vertebral body. J Biomech. 2015 May 01; 48(7):1264-9.
Theoretical effects of fully ductile versus fully brittle behaviors of bone tissue on the strength of the human proximal femur and vertebral body.
Yu EW, Bouxsein ML, Putman MS, Monis EL, Roy AE, Pratt JS, Butsch WS, Finkelstein JS
Two-year changes in bone density after Roux-en-Y gastric bypass surgery. J Clin Endocrinol Metab. 2015 Apr; 100(4):1452-9.
Two-year changes in bone density after Roux-en-Y gastric bypass surgery.
Bala Y, Bui QM, Wang XF, Iuliano S, Wang Q, Ghasem-Zadeh A, Rozental TD, Bouxsein ML, Zebaze RM, Seeman E
Trabecular and cortical microstructure and fragility of the distal radius in women. J Bone Miner Res. 2015 Apr; 30(4):621-9.
Trabecular and cortical microstructure and fragility of the distal radius in women.
Kiel DP, Hannan MT, Barton BA, Bouxsein ML, Sisson E, Lang T, Allaire B, Dewkett D, Carroll D, Magaziner J, Shane E, Leary ET, Zimmerman S, Rubin CT
Low-Magnitude Mechanical Stimulation to Improve Bone Density in Persons of Advanced Age: A Randomized, Placebo-Controlled Trial. J Bone Miner Res. 2015 Jul; 30(7):1319-28.
Low-Magnitude Mechanical Stimulation to Improve Bone Density in Persons of Advanced Age: A Randomized, Placebo-Controlled Trial.
Mitchell DM, Tuck P, Ackerman KE, Cano Sokoloff N, Woolley R, Slattery M, Lee H, Bouxsein ML, Misra M
Altered trabecular bone morphology in adolescent and young adult athletes with menstrual dysfunction. Bone. 2015 Dec; 81:24-30.
Altered trabecular bone morphology in adolescent and young adult athletes with menstrual dysfunction.
Singhal V, Goh BC, Bouxsein ML, Faugere MC, DiGirolamo DJ
Osteoblast-restricted Disruption of the Growth Hormone Receptor in Mice Results in Sexually Dimorphic Skeletal Phenotypes. Bone Res. 2013 Mar; 1(1):85-97.
Osteoblast-restricted Disruption of the Growth Hormone Receptor in Mice Results in Sexually Dimorphic Skeletal Phenotypes.
Bachmann KN, Bruno AG, Bredella MA, Schorr M, Lawson EA, Gill CM, Singhal V, Meenaghan E, Gerweck AV, Eddy KT, Ebrahimi S, Koman SL, Greenblatt JM, Keane RJ, Weigel T, Dechant E, Misra M, Klibanski A, Bouxsein ML, Miller KK
Vertebral Strength and Estimated Fracture Risk Across the BMI Spectrum in Women. J Bone Miner Res. 2016 Feb; 31(2):281-8.
Vertebral Strength and Estimated Fracture Risk Across the BMI Spectrum in Women.
Meng X, Bruno AG, Cheng B, Wang W, Bouxsein ML, Anderson DE
Incorporating Six Degree-of-Freedom Intervertebral Joint Stiffness in a Lumbar Spine Musculoskeletal Model-Method and Performance in Flexed Postures. J Biomech Eng. 2015 Oct; 137(10):101008.
Incorporating Six Degree-of-Freedom Intervertebral Joint Stiffness in a Lumbar Spine Musculoskeletal Model-Method and Performance in Flexed Postures.
Rozental TD, Herder LM, Walley KC, Zurakowski D, Coyle K, Bouxsein ML, Wolf JM
25-Hydroxyvitamin-D and Bone Turnover Marker Levels in Patients with Distal Radial Fracture. J Bone Joint Surg Am. 2015 Oct 21; 97(20):1685-93.
25-Hydroxyvitamin-D and Bone Turnover Marker Levels in Patients with Distal Radial Fracture.
Effect of type 2 diabetes-related non-enzymatic glycation on bone biomechanical properties. Bone. 2016 Jan; 82:21-7.
Effect of type 2 diabetes-related non-enzymatic glycation on bone biomechanical properties.
the Role of Beta-Arrestin 2 in Regulating the Response of Bone to Parathyroid Hormone (PTH) Administration
Effect of Age-, Sex- and Location-Specific Differences in Trunk Muscle Geometry on Estimates of Loading in the Thoracic and Lumbar Spine
Shanbhogue VV, Mitchell DM, Rosen CJ, Bouxsein ML
Type 2 diabetes and the skeleton: new insights into sweet bones. Lancet Diabetes Endocrinol. 2016 Feb; 4(2):159-73.
Type 2 diabetes and the skeleton: new insights into sweet bones.
Yu EW, Carmody JS, Brooks DJ, LaJoie S, Kaplan LM, Bouxsein ML
Cortical and trabecular deterioration in mouse models of Roux-en-Y gastric bypass. Bone. 2016 Apr; 85:23-8.
Cortical and trabecular deterioration in mouse models of Roux-en-Y gastric bypass.
Jonscher KR, Alfonso-Garcia A, Suhalim JL, Orlicky DJ, Potma EO, Ferguson VL, Bouxsein ML, Bateman TA, Stodieck LS, Levi M, Friedman JE, Gridley DS, Pecaut MJ
Spaceflight Activates Lipotoxic Pathways in Mouse Liver. PLoS One. 2016; 11(4):e0152877.
Spaceflight Activates Lipotoxic Pathways in Mouse Liver.
Anderson DE, Mannen EM, Sis HL, Wong BM, Cadel ES, Friis EA, Bouxsein ML
Effects of follower load and rib cage on intervertebral disc pressure and sagittal plane curvature in static tests of cadaveric thoracic spines. J Biomech. 2016 05 03; 49(7):1078-1084.
Effects of follower load and rib cage on intervertebral disc pressure and sagittal plane curvature in static tests of cadaveric thoracic spines.
Liu ES, Martins JS, Raimann A, Chae BT, Brooks DJ, Jorgetti V, Bouxsein ML, Demay MB
1,25-Dihydroxyvitamin D Alone Improves Skeletal Growth, Microarchitecture, and Strength in a Murine Model of XLH, Despite Enhanced FGF23 Expression. J Bone Miner Res. 2016 05; 31(5):929-39.
1,25-Dihydroxyvitamin D Alone Improves Skeletal Growth, Microarchitecture, and Strength in a Murine Model of XLH, Despite Enhanced FGF23 Expression.
Anderson DE, Quinn E, Parker E, Allaire BT, Muir JW, Rubin CT, Magaziner J, Hannan MT, Bouxsein ML, Kiel DP
Associations of Computed Tomography-Based Trunk Muscle Size and Density With Balance and Falls in Older Adults. J Gerontol A Biol Sci Med Sci. 2016 06; 71(6):811-6.
Associations of Computed Tomography-Based Trunk Muscle Size and Density With Balance and Falls in Older Adults.
Tsai JN, Uihlein AV, Burnett-Bowie SM, Neer RM, Derrico NP, Lee H, Bouxsein ML, Leder BZ
Effects of Two Years of Teriparatide, Denosumab, or Both on Bone Microarchitecture and Strength (DATA-HRpQCT study). J Clin Endocrinol Metab. 2016 05; 101(5):2023-30.
Effects of Two Years of Teriparatide, Denosumab, or Both on Bone Microarchitecture and Strength (DATA-HRpQCT study).
Hughes JM, Bulathsinhala L, McKinnon CJ, Matheny RW, Kardouni JR, Bouxsein ML
Risk Of Stress Fracture Varies By Race/Ethnicity In U.S. Army Soldiers: 3094 Board #159 June 3, 3: 30 PM - 5: 00 PM. Med Sci Sports Exerc. 2016 May; 48(5 Suppl 1):877-8.
Risk Of Stress Fracture Varies By Race/Ethnicity In U.S. Army Soldiers: 3094 Board #159 June 3, 3: 30 PM - 5: 00 PM.
Devlin MJ, Brooks DJ, Conlon C, Vliet Mv, Louis L, Rosen CJ, Bouxsein ML
Daily leptin blunts marrow fat but does not impact bone mass in calorie-restricted mice. J Endocrinol. 2016 06; 229(3):295-306.
Daily leptin blunts marrow fat but does not impact bone mass in calorie-restricted mice.
Guerriere KI, Gaffney-Stomberg E, Hughes JM, Staab JS, Bouxsein ML, Matheny RW
Effects Of An Acute Bout Of Plyometric Exercise On Serum Sclerostin Over A 72-hour Period In Men: 693 Board #9 June 1, 3: 30 PM - 5: 00 PM. Med Sci Sports Exerc. 2016 May; 48(5 Suppl 1):184-5.
Effects Of An Acute Bout Of Plyometric Exercise On Serum Sclerostin Over A 72-hour Period In Men: 693 Board #9 June 1, 3: 30 PM - 5: 00 PM.
Popp KL, Hughes JM, McKinnon CJ, Kardouni JR, Matheny RW, Bouxsein ML
Ethinyl Estradiol-Containing Hormonal Contraceptive Prescriptions are Associated with Reduced Stress Fracture Risk in Female Soldiers: 3096 Board #161 June 3, 3: 30 PM - 5: 00 PM. Med Sci Sports Exerc. 2016 May; 48(5 Suppl 1):878.
Ethinyl Estradiol-Containing Hormonal Contraceptive Prescriptions are Associated with Reduced Stress Fracture Risk in Female Soldiers: 3096 Board #161 June 3, 3: 30 PM - 5: 00 PM.
Leder BZ, Tsai JN, Burnett-Bowie SA, Bouxsein ML, Neer RM
Letter to the editor in response to the commentary, "Concurrent administration of PTH and antiresorptives: Additive effects or DXA cosmetics. Bone. 2016 08; 89:73-74.
Letter to the editor in response to the commentary, "Concurrent administration of PTH and antiresorptives: Additive effects or DXA cosmetics.
Misra M, Ackerman KE, Bredella MA, Stanford FC, Faje AT, Nordberg A, Derrico NP, Bouxsein ML
Journal of racial and ethnic health disparities
Racial Differences in Bone Microarchitecture and Estimated Strength at the Distal Radius and Distal Tibia in Older Adolescent Girls: a Cross-Sectional Study. J Racial Ethn Health Disparities. 2017 08; 4(4):587-598.
Racial Differences in Bone Microarchitecture and Estimated Strength at the Distal Radius and Distal Tibia in Older Adolescent Girls: a Cross-Sectional Study.
Putman MS, Greenblatt LB, Sicilian L, Uluer A, Lapey A, Sawicki G, Gordon CM, Bouxsein ML, Finkelstein JS
Young adults with cystic fibrosis have altered trabecular microstructure by ITS-based morphological analysis. Osteoporos Int. 2016 08; 27(8):2497-505.
Young adults with cystic fibrosis have altered trabecular microstructure by ITS-based morphological analysis.
Yau MS, Demissie S, Zhou Y, Anderson DE, Lorbergs AL, Kiel DP, Allaire BT, Yang L, Cupples LA, Travison TG, Bouxsein ML, Karasik D, Samelson EJ
Heritability of Thoracic Spine Curvature and Genetic Correlations With Other Spine Traits: The Framingham Study. J Bone Miner Res. 2016 12; 31(12):2077-2084.
Heritability of Thoracic Spine Curvature and Genetic Correlations With Other Spine Traits: The Framingham Study.
Shanbhogue VV, Finkelstein JS, Bouxsein ML, Yu EW
Association Between Insulin Resistance and Bone Structure in Nondiabetic Postmenopausal Women. J Clin Endocrinol Metab. 2016 08; 101(8):3114-22.
Association Between Insulin Resistance and Bone Structure in Nondiabetic Postmenopausal Women.
Microcomputed Tomography Device (Scanco UCT40)
CALCANEAL ULTRASOUND AND FRACTURE RISK PREDICTION
Biomechanics of Vertebral Fractures: The Framingham QCT Study
Musculoskeletal Response to Partial Weight Bearing
REGULATION OF PTH ACTIVITY IN BONE BY BETA-ARRESTIN
Effect of Perinatal Diet on Developmental Programming of the Skeleton
LOW COST METHODS TO ASSESS OSTEOPOROTIC FRACTURE RISK
Predicting Hip Fracture Using a Biomechanical Approach
The Gut Microbiome and Bone Microarchitecture
Role of Bone Tissue Material Properties in Atypical Femoral Fractures
Bachmann KN, Schorr M, Bruno AG, Bredella MA, Lawson EA, Gill CM, Singhal V, Meenaghan E, Gerweck AV, Slattery M, Eddy KT, Ebrahimi S, Koman SL, Greenblatt JM, Keane RJ, Weigel T, Misra M, Bouxsein ML, Klibanski A, Miller KK
Vertebral Volumetric Bone Density and Strength Are Impaired in Women With Low-Weight and Atypical Anorexia Nervosa. J Clin Endocrinol Metab. 2017 01 01; 102(1):57-68.
Vertebral Volumetric Bone Density and Strength Are Impaired in Women With Low-Weight and Atypical Anorexia Nervosa.
Wein MN, Liang Y, Goransson O, Sundberg TB, Wang J, Williams EA, O'Meara MJ, Govea N, Beqo B, Nishimori S, Nagano K, Brooks DJ, Martins JS, Corbin B, Anselmo A, Sadreyev R, Wu JY, Sakamoto K, Foretz M, Xavier RJ, Baron R, Bouxsein ML, Gardella TJ, Divieti-Pajevic P, Gray NS, Kronenberg HM
SIKs control osteocyte responses to parathyroid hormone. Nat Commun. 2016 10 19; 7:13176.
SIKs control osteocyte responses to parathyroid hormone.
Sis HL, Mannen EM, Wong BM, Cadel ES, Bouxsein ML, Anderson DE, Friis EA
Effect of follower load on motion and stiffness of the human thoracic spine with intact rib cage. J Biomech. 2016 10 03; 49(14):3252-3259.
Effect of follower load on motion and stiffness of the human thoracic spine with intact rib cage.
Allaire BT, DePaolis Kaluza MC, Bruno AG, Samelson EJ, Kiel DP, Anderson DE, Bouxsein ML
European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society
Evaluation of a new approach to compute intervertebral disc height measurements from lateral radiographic views of the spine. Eur Spine J. 2017 01; 26(1):167-172.
Evaluation of a new approach to compute intervertebral disc height measurements from lateral radiographic views of the spine.
Karasik D, Demissie S, Zhou Y, Lu D, Broe KE, Bouxsein ML, Cupples LA, Kiel DP
Heritability and Genetic Correlations for Bone Microarchitecture: The Framingham Study Families. J Bone Miner Res. 2017 01; 32(1):106-114.
Heritability and Genetic Correlations for Bone Microarchitecture: The Framingham Study Families.
Ko FC, Karim L, Brooks DJ, Bouxsein ML, Demay MB
Bisphosphonate Withdrawal: Effects on Bone Formation and Bone Resorption in Maturing Male Mice. J Bone Miner Res. 2017 04; 32(4):814-820.
Bisphosphonate Withdrawal: Effects on Bone Formation and Bone Resorption in Maturing Male Mice.
Putman MS, Yu EW, Lin D, Darakananda K, Finkelstein JS, Bouxsein ML
Differences in Trabecular Microstructure Between Black and White Women Assessed by Individual Trabecular Segmentation Analysis of HR-pQCT Images. J Bone Miner Res. 2017 May; 32(5):1100-1108.
Differences in Trabecular Microstructure Between Black and White Women Assessed by Individual Trabecular Segmentation Analysis of HR-pQCT Images.
Liu CT, Broe KE, Zhou Y, Boyd SK, Cupples LA, Hannan MT, Lim E, McLean RR, Samelson EJ, Bouxsein ML, Kiel DP
Visceral Adipose Tissue Is Associated With Bone Microarchitecture in the Framingham Osteoporosis Study. J Bone Miner Res. 2017 01; 32(1):143-150.
Visceral Adipose Tissue Is Associated With Bone Microarchitecture in the Framingham Osteoporosis Study.
Bonaretti S, Vilayphiou N, Chan CM, Yu A, Nishiyama K, Liu D, Boutroy S, Ghasem-Zadeh A, Boyd SK, Chapurlat R, McKay H, Shane E, Bouxsein ML, Black DM, Majumdar S, Orwoll ES, Lang TF, Khosla S, Burghardt AJ
Operator variability in scan positioning is a major component of HR-pQCT precision error and is reduced by standardized training. Osteoporos Int. 2017 01; 28(1):245-257.
Operator variability in scan positioning is a major component of HR-pQCT precision error and is reduced by standardized training.
Jin YR, Stohn JP, Wang Q, Nagano K, Baron R, Bouxsein ML, Rosen CJ, Adarichev VA, Lindner V
Inhibition of osteoclast differentiation and collagen antibody-induced arthritis by CTHRC1. Bone. 2017 04; 97:153-167.
Inhibition of osteoclast differentiation and collagen antibody-induced arthritis by CTHRC1.
Bruno AG, Mokhtarzadeh H, Allaire BT, Velie KR, De Paolis Kaluza MC, Anderson DE, Bouxsein ML
Incorporation of CT-based measurements of trunk anatomy into subject-specific musculoskeletal models of the spine influences vertebral loading predictions. J Orthop Res. 2017 10; 35(10):2164-2173.
Incorporation of CT-based measurements of trunk anatomy into subject-specific musculoskeletal models of the spine influences vertebral loading predictions.
Comparison of cyclic and impact-based reference point indentation measurements in human cadaveric tibia. Bone. 2018 Jan; 106:90-95.
Comparison of cyclic and impact-based reference point indentation measurements in human cadaveric tibia.
Nielson CM, Liu CT, Smith AV, Ackert-Bicknell CL, Reppe S, Jakobsdottir J, Wassel C, Register TC, Oei L, Alonso N, Oei EH, Parimi N, Samelson EJ, Nalls MA, Zmuda J, Lang T, Bouxsein M, Latourelle J, Claussnitzer M, Siggeirsdottir K, Srikanth P, Lorentzen E, Vandenput L, Langefeld C, Raffield L, Terry G, Cox AJ, Allison MA, Criqui MH, Bowden D, Ikram MA, Mellström D, Karlsson MK, Carr J, Budoff M, Phillips C, Cupples LA, Chou WC, Myers RH, Ralston SH, Gautvik KM, Cawthon PM, Cummings S, Karasik D, Rivadeneira F, Gudnason V, Orwoll ES, Harris TB, Ohlsson C, Kiel DP, Hsu YH
Novel Genetic Variants Associated With Increased Vertebral Volumetric BMD, Reduced Vertebral Fracture Risk, and Increased Expression of SLC1A3 and EPHB2. J Bone Miner Res. 2016 12; 31(12):2085-2097.
Novel Genetic Variants Associated With Increased Vertebral Volumetric BMD, Reduced Vertebral Fracture Risk, and Increased Expression of SLC1A3 and EPHB2.
Li G, Bouxsein ML, Luppen C, Li XJ, Wood M, Seeherman HJ, Wozney JM, Simpson H
Bone consolidation is enhanced by rhBMP-2 in a rabbit model of distraction osteogenesis. J Orthop Res. 2002 Jul; 20(4):779-88.
Bone consolidation is enhanced by rhBMP-2 in a rabbit model of distraction osteogenesis.
Kacena MA, Shivdasani RA, Wilson K, Xi Y, Troiano N, Nazarian A, Gundberg CM, Bouxsein ML, Lorenzo JA, Horowitz MC
Megakaryocyte-osteoblast interaction revealed in mice deficient in transcription factors GATA-1 and NF-E2. J Bone Miner Res. 2004 Apr; 19(4):652-60.
Megakaryocyte-osteoblast interaction revealed in mice deficient in transcription factors GATA-1 and NF-E2.
Bertone AL, Pittman DD, Bouxsein ML, Li J, Clancy B, Seeherman HJ
Adenoviral-mediated transfer of human BMP-6 gene accelerates healing in a rabbit ulnar osteotomy model. J Orthop Res. 2004 Nov; 22(6):1261-70.
Adenoviral-mediated transfer of human BMP-6 gene accelerates healing in a rabbit ulnar osteotomy model.
Holmen SL, Giambernardi TA, Zylstra CR, Buckner-Berghuis BD, Resau JH, Hess JF, Glatt V, Bouxsein ML, Ai M, Warman ML, Williams BO
Decreased BMD and limb deformities in mice carrying mutations in both Lrp5 and Lrp6. J Bone Miner Res. 2004 Dec; 19(12):2033-40.
Decreased BMD and limb deformities in mice carrying mutations in both Lrp5 and Lrp6.
Tibial ultrasound velocity measured in situ predicts the material properties of tibial cortical bone. Bone. 1997 Jul; 21(1):119-25.
Tibial ultrasound velocity measured in situ predicts the material properties of tibial cortical bone.
Prediction of the strength of the elderly proximal femur by bone mineral density and quantitative ultrasound measurements of the heel and tibia. Bone. 1999 Jul; 25(1):49-54.
Prediction of the strength of the elderly proximal femur by bone mineral density and quantitative ultrasound measurements of the heel and tibia.
Forearm bone mineral densitometry cannot be used to monitor response to alendronate therapy in postmenopausal women. Osteoporos Int. 1999; 10(6):505-9.
Forearm bone mineral densitometry cannot be used to monitor response to alendronate therapy in postmenopausal women.
Snow-Harter C, Bouxsein ML, Lewis BT, Carter DR, Marcus R
Effects of resistance and endurance exercise on bone mineral status of young women: a randomized exercise intervention trial. J Bone Miner Res. 1992 Jul; 7(7):761-9.
Effects of resistance and endurance exercise on bone mineral status of young women: a randomized exercise intervention trial.
Diez-Perez A, Bouxsein ML, Eriksen EF, Khosla S, Nyman JS, Papapoulos S, Tang SY
Technical note: Recommendations for a standard procedure to assess cortical bone at the tissue-level in vivo using impact microindentation. Bone Rep. 2016 Dec; 5:181-185.
Technical note: Recommendations for a standard procedure to assess cortical bone at the tissue-level in vivo using impact microindentation.
Hughes JM, Popp KL, Yanovich R, Bouxsein ML, Matheny RW
The role of adaptive bone formation in the etiology of stress fracture. Exp Biol Med (Maywood). 2017 05; 242(9):897-906.
The role of adaptive bone formation in the etiology of stress fracture.
Correction: Spaceflight Activates Lipotoxic Pathways in Mouse Liver. PLoS One. 2016; 11(5):e0155282.
Correction: Spaceflight Activates Lipotoxic Pathways in Mouse Liver.
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In vivo assessment of trabecular bone microarchitecture by high-resolution peripheral quantitative computed tomography.
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Scattering of ultrasound in cancellous bone: predictions from a theoretical model. J Biomech. 2000 Apr; 33(4):503-6.
Scattering of ultrasound in cancellous bone: predictions from a theoretical model.
Bruno AG, Burkhart K, Allaire B, Anderson DE, Bouxsein ML
Spinal Loading Patterns From Biomechanical Modeling Explain the High Incidence of Vertebral Fractures in the Thoracolumbar Region. J Bone Miner Res. 2017 Jun; 32(6):1282-1290.
Spinal Loading Patterns From Biomechanical Modeling Explain the High Incidence of Vertebral Fractures in the Thoracolumbar Region.
Maddaloni E, D'Eon S, Hastings S, Tinsley LJ, Napoli N, Khamaisi M, Bouxsein ML, Fouda SMR, Keenan HA
Bone health in subjects with type 1 diabetes for more than 50 years. Acta Diabetol. 2017 May; 54(5):479-488.
Bone health in subjects with type 1 diabetes for more than 50 years.
An update on osteoporosis pathogenesis, diagnosis, and treatment. Bone. 2017 05; 98:37.
An update on osteoporosis pathogenesis, diagnosis, and treatment.
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Sclerostin antibody inhibits skeletal deterioration in mice exposed to partial weight-bearing. Life Sci Space Res (Amst). 2017 Feb; 12:32-38.
Sclerostin antibody inhibits skeletal deterioration in mice exposed to partial weight-bearing.
Corrigendum: SIKs control osteocyte responses to parathyroid hormone. Nat Commun. 2017 02 22; 8:14745.
Corrigendum: SIKs control osteocyte responses to parathyroid hormone.
Bulathsinhala L, Hughes JM, McKinnon CJ, Kardouni JR, Guerriere KI, Popp KL, Matheny RW, Bouxsein ML
Risk of Stress Fracture Varies by Race/Ethnic Origin in a Cohort Study of 1.3 Million US Army Soldiers. J Bone Miner Res. 2017 Jul; 32(7):1546-1553.
Risk of Stress Fracture Varies by Race/Ethnic Origin in a Cohort Study of 1.3 Million US Army Soldiers.
Melton LJ, Riggs BL, Leibson CL, Achenbach SJ, Camp JJ, Bouxsein ML, Atkinson EJ, Robb RA, Khosla S
A bone structural basis for fracture risk in diabetes. J Clin Endocrinol Metab. 2008 Dec; 93(12):4804-9.
A bone structural basis for fracture risk in diabetes.
Bouxsein ML, Palermo L, Yeung C, Black DM
Digital X-ray radiogrammetry predicts hip, wrist and vertebral fracture risk in elderly women: a prospective analysis from the study of osteoporotic fractures. Osteoporos Int. 2002 May; 13(5):358-65.
Digital X-ray radiogrammetry predicts hip, wrist and vertebral fracture risk in elderly women: a prospective analysis from the study of osteoporotic fractures.
Knopp E, Troiano N, Bouxsein M, Sun BH, Lostritto K, Gundberg C, Dziura J, Insogna K
The effect of aging on the skeletal response to intermittent treatment with parathyroid hormone. Endocrinology. 2005 Apr; 146(4):1983-90.
The effect of aging on the skeletal response to intermittent treatment with parathyroid hormone.
Non-invasive measurements of bone strength: promise and peril. J Musculoskelet Neuronal Interact. 2004 Dec; 4(4):404-5.
Non-invasive measurements of bone strength: promise and peril.
Bouxsein ML, Michaeli DA, Plass DB, Schick DA, Melton ME
Precision and accuracy of computed digital absorptiometry for assessment of bone density of the hand. Osteoporos Int. 1997; 7(5):444-9.
Precision and accuracy of computed digital absorptiometry for assessment of bone density of the hand.
Turner CH, Sun Q, Schriefer J, Pitner N, Price R, Bouxsein ML, Rosen CJ, Donahue LR, Shultz KL, Beamer WG
Congenic mice reveal sex-specific genetic regulation of femoral structure and strength. Calcif Tissue Int. 2003 Sep; 73(3):297-303.
Congenic mice reveal sex-specific genetic regulation of femoral structure and strength.
Riggs BL, Melton LJ, Robb RA, Camp JJ, Atkinson EJ, Oberg AL, Rouleau PA, McCollough CH, Khosla S, Bouxsein ML
Population-based analysis of the relationship of whole bone strength indices and fall-related loads to age- and sex-specific patterns of hip and wrist fractures. J Bone Miner Res. 2006 Feb; 21(2):315-23.
Population-based analysis of the relationship of whole bone strength indices and fall-related loads to age- and sex-specific patterns of hip and wrist fractures.
Liu X, Bruxvoort KJ, Zylstra CR, Liu J, Cichowski R, Faugere MC, Bouxsein ML, Wan C, Williams BO, Clemens TL
Lifelong accumulation of bone in mice lacking Pten in osteoblasts. Proc Natl Acad Sci U S A. 2007 Feb 13; 104(7):2259-64.
Lifelong accumulation of bone in mice lacking Pten in osteoblasts.
Quantitative ultrasound of the calcaneus reflects the mechanical properties of calcaneal trabecular bone. J Bone Miner Res. 1997 May; 12(5):839-46.
Quantitative ultrasound of the calcaneus reflects the mechanical properties of calcaneal trabecular bone.
Skeletal Fragility in Type 2 Diabetes Mellitus
Yakar S, Setser J, Zhao H, Stannard B, Haluzik M, Glatt V, Bouxsein ML, Kopchick JJ, LeRoith D
Inhibition of growth hormone action improves insulin sensitivity in liver IGF-1-deficient mice. J Clin Invest. 2004 Jan; 113(1):96-105.
Inhibition of growth hormone action improves insulin sensitivity in liver IGF-1-deficient mice.
Pierroz DD, Bonnet N, Bianchi EN, Bouxsein ML, Baldock PA, Rizzoli R, Ferrari SL
Deletion of ß-adrenergic receptor 1, 2, or both leads to different bone phenotypes and response to mechanical stimulation. J Bone Miner Res. 2012 Jun; 27(6):1252-62.
Deletion of ß-adrenergic receptor 1, 2, or both leads to different bone phenotypes and response to mechanical stimulation.
Bruno AG, Anderson DE, D'Agostino J, Bouxsein ML
The effect of thoracic kyphosis and sagittal plane alignment on vertebral compressive loading. J Bone Miner Res. 2012 Oct; 27(10):2144-51.
The effect of thoracic kyphosis and sagittal plane alignment on vertebral compressive loading.
Luppen CA, Blake CA, Ammirati KM, Stevens ML, Seeherman HJ, Wozney JM, Bouxsein ML
Recombinant human bone morphogenetic protein-2 enhances osteotomy healing in glucocorticoid-treated rabbits. J Bone Miner Res. 2002 Feb; 17(2):301-10.
Recombinant human bone morphogenetic protein-2 enhances osteotomy healing in glucocorticoid-treated rabbits.
Effect of temperature on ultrasonic properties of the calcaneus in situ. Osteoporos Int. 2002 Nov; 13(11):888-92.
Effect of temperature on ultrasonic properties of the calcaneus in situ.
Best practice & research. Clinical rheumatology
Determinants of skeletal fragility. Best Pract Res Clin Rheumatol. 2005 Dec; 19(6):897-911.
Turner CH, Hsieh YF, Müller R, Bouxsein ML, Baylink DJ, Rosen CJ, Grynpas MD, Donahue LR, Beamer WG
Genetic regulation of cortical and trabecular bone strength and microstructure in inbred strains of mice. J Bone Miner Res. 2000 Jun; 15(6):1126-31.
Genetic regulation of cortical and trabecular bone strength and microstructure in inbred strains of mice.
Zhang M, Xuan S, Bouxsein ML, von Stechow D, Akeno N, Faugere MC, Malluche H, Zhao G, Rosen CJ, Efstratiadis A, Clemens TL
Osteoblast-specific knockout of the insulin-like growth factor (IGF) receptor gene reveals an essential role of IGF signaling in bone matrix mineralization. J Biol Chem. 2002 Nov 15; 277(46):44005-12.
Osteoblast-specific knockout of the insulin-like growth factor (IGF) receptor gene reveals an essential role of IGF signaling in bone matrix mineralization.
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Pharmacologic targeting of a stem/progenitor population in vivo is associated with enhanced bone regeneration in mice. J Clin Invest. 2008 Feb; 118(2):491-504.
Pharmacologic targeting of a stem/progenitor population in vivo is associated with enhanced bone regeneration in mice.
Theoretical implications of the biomechanical fracture threshold. J Bone Miner Res. 2008 Oct; 23(10):1541-7.
Theoretical implications of the biomechanical fracture threshold.
McLean RR, Hannan MT, Epstein BE, Bouxsein ML, Cupples LA, Murabito J, Kiel DP
Elderly cohort study subjects unable to return for follow-up have lower bone mass than those who can return. Am J Epidemiol. 2000 Apr 01; 151(7):689-92.
Elderly cohort study subjects unable to return for follow-up have lower bone mass than those who can return.
Bouxsein ML, Rosen CJ, Turner CH, Ackert CL, Shultz KL, Donahue LR, Churchill G, Adamo ML, Powell DR, Turner RT, Muller R, Beamer WG
Generation of a new congenic mouse strain to test the relationships among serum insulin-like growth factor I, bone mineral density, and skeletal morphology in vivo. J Bone Miner Res. 2002 Apr; 17(4):570-9.
Generation of a new congenic mouse strain to test the relationships among serum insulin-like growth factor I, bone mineral density, and skeletal morphology in vivo.
Ackerman KE, Nazem T, Chapko D, Russell M, Mendes N, Taylor AP, Bouxsein ML, Misra M
Bone microarchitecture is impaired in adolescent amenorrheic athletes compared with eumenorrheic athletes and nonathletic controls. J Clin Endocrinol Metab. 2011 Oct; 96(10):3123-33.
Bone microarchitecture is impaired in adolescent amenorrheic athletes compared with eumenorrheic athletes and nonathletic controls.
Bouxsein ML, Myers KS, Shultz KL, Donahue LR, Rosen CJ, Beamer WG
Ovariectomy-induced bone loss varies among inbred strains of mice. J Bone Miner Res. 2005 Jul; 20(7):1085-92.
Ovariectomy-induced bone loss varies among inbred strains of mice.
Notini AJ, McManus JF, Moore A, Bouxsein M, Jimenez M, Chiu WS, Glatt V, Kream BE, Handelsman DJ, Morris HA, Zajac JD, Davey RA
Osteoblast deletion of exon 3 of the androgen receptor gene results in trabecular bone loss in adult male mice. J Bone Miner Res. 2007 Mar; 22(3):347-56.
Osteoblast deletion of exon 3 of the androgen receptor gene results in trabecular bone loss in adult male mice.
Burkhart KA, Bruno AG, Bouxsein ML, Bean JF, Anderson DE
Estimating apparent maximum muscle stress of trunk extensor muscles in older adults using subject-specific musculoskeletal models. J Orthop Res. 2018 01; 36(1):498-505.
Estimating apparent maximum muscle stress of trunk extensor muscles in older adults using subject-specific musculoskeletal models.
Yakar S, Bouxsein ML, Canalis E, Sun H, Glatt V, Gundberg C, Cohen P, Hwang D, Boisclair Y, Leroith D, Rosen CJ
The ternary IGF complex influences postnatal bone acquisition and the skeletal response to intermittent parathyroid hormone. J Endocrinol. 2006 May; 189(2):289-99.
The ternary IGF complex influences postnatal bone acquisition and the skeletal response to intermittent parathyroid hormone.
Mechanisms of disease: is osteoporosis the obesity of bone? Nat Clin Pract Rheumatol. 2006 Jan; 2(1):35-43.
Mechanisms of disease: is osteoporosis the obesity of bone?
Glatt V, Canalis E, Stadmeyer L, Bouxsein ML
Age-related changes in trabecular architecture differ in female and male C57BL/6J mice. J Bone Miner Res. 2007 Aug; 22(8):1197-207.
Age-related changes in trabecular architecture differ in female and male C57BL/6J mice.
Snow-Harter C, Bouxsein M, Lewis B, Charette S, Weinstein P, Marcus R
Muscle strength as a predictor of bone mineral density in young women. J Bone Miner Res. 1990 Jun; 5(6):589-95.
Muscle strength as a predictor of bone mineral density in young women.
Wright LE, Christian PJ, Rivera Z, Van Alstine WG, Funk JL, Bouxsein ML, Hoyer PB
Comparison of skeletal effects of ovariectomy versus chemically induced ovarian failure in mice. J Bone Miner Res. 2008 Aug; 23(8):1296-303.
Comparison of skeletal effects of ovariectomy versus chemically induced ovarian failure in mice.
Ackert-Bicknell CL, Demissie S, Marín de Evsikova C, Hsu YH, DeMambro VE, Karasik D, Cupples LA, Ordovas JM, Tucker KL, Cho K, Canalis E, Paigen B, Churchill GA, Forejt J, Beamer WG, Ferrari S, Bouxsein ML, Kiel DP, Rosen CJ
PPARG by dietary fat interaction influences bone mass in mice and humans. J Bone Miner Res. 2008 Sep; 23(9):1398-408.
PPARG by dietary fat interaction influences bone mass in mice and humans.
Bouxsein ML, Devlin MJ, Glatt V, Dhillon H, Pierroz DD, Ferrari SL
Mice lacking beta-adrenergic receptors have increased bone mass but are not protected from deleterious skeletal effects of ovariectomy. Endocrinology. 2009 Jan; 150(1):144-52.
Mice lacking beta-adrenergic receptors have increased bone mass but are not protected from deleterious skeletal effects of ovariectomy.
Bouxsein ML, Chen P, Glass EV, Kallmes DF, Delmas PD, Mitlak BH
Teriparatide and raloxifene reduce the risk of new adjacent vertebral fractures in postmenopausal women with osteoporosis. Results from two randomized controlled trials. J Bone Joint Surg Am. 2009 Jun; 91(6):1329-38.
Teriparatide and raloxifene reduce the risk of new adjacent vertebral fractures in postmenopausal women with osteoporosis. Results from two randomized controlled trials.
Garnero P, Borel O, Gineyts E, Duboeuf F, Solberg H, Bouxsein ML, Christiansen C, Delmas PD
Extracellular post-translational modifications of collagen are major determinants of biomechanical properties of fetal bovine cortical bone. Bone. 2006 Mar; 38(3):300-9.
Extracellular post-translational modifications of collagen are major determinants of biomechanical properties of fetal bovine cortical bone.
Johannesdottir F, Thrall E, Muller J, Keaveny TM, Kopperdahl DL, Bouxsein ML
Comparison of non-invasive assessments of strength of the proximal femur. Bone. 2017 Dec; 105:93-102.
Comparison of non-invasive assessments of strength of the proximal femur.
Nature clinical practice. Endocrinology & metabolism
Vertebral fracture assessment using standard bone densitometry equipment predicts incident fractures in women. Nat Clin Pract Endocrinol Metab. 2008 Dec; 4(12):652-3.
Vertebral fracture assessment using standard bone densitometry equipment predicts incident fractures in women.
Beth Israel Deaconess Medical Center, RN115
Seeherman HJ, Li XJ, Bouxsein ML, Wozney JM
rhBMP-2 induces transient bone resorption followed by bone formation in a nonhuman primate core-defect model. J Bone Joint Surg Am. 2010 Feb; 92(2):411-26.
rhBMP-2 induces transient bone resorption followed by bone formation in a nonhuman primate core-defect model.
Bouxsein ML, Boyd SK, Christiansen BA, Guldberg RE, Jepsen KJ, Müller R
Guidelines for assessment of bone microstructure in rodents using micro-computed tomography. J Bone Miner Res. 2010 Jul; 25(7):1468-86.
Guidelines for assessment of bone microstructure in rodents using micro-computed tomography.
Wegrzyn J, Roux JP, Arlot ME, Boutroy S, Vilayphiou N, Guyen O, Delmas PD, Chapurlat R, Bouxsein ML
Role of trabecular microarchitecture and its heterogeneity parameters in the mechanical behavior of ex vivo human L3 vertebrae. J Bone Miner Res. 2010 Nov; 25(11):2324-31.
Role of trabecular microarchitecture and its heterogeneity parameters in the mechanical behavior of ex vivo human L3 vertebrae.
Seeherman H, Li R, Bouxsein M, Kim H, Li XJ, Smith-Adaline EA, Aiolova M, Wozney JM
rhBMP-2/calcium phosphate matrix accelerates osteotomy-site healing in a nonhuman primate model at multiple treatment times and concentrations. J Bone Joint Surg Am. 2006 Jan; 88(1):144-60.
rhBMP-2/calcium phosphate matrix accelerates osteotomy-site healing in a nonhuman primate model at multiple treatment times and concentrations.
Viguet-Carrin S, Roux JP, Arlot ME, Merabet Z, Leeming DJ, Byrjalsen I, Delmas PD, Bouxsein ML
Contribution of the advanced glycation end product pentosidine and of maturation of type I collagen to compressive biomechanical properties of human lumbar vertebrae. Bone. 2006 Nov; 39(5):1073-1079.
Contribution of the advanced glycation end product pentosidine and of maturation of type I collagen to compressive biomechanical properties of human lumbar vertebrae.
Putman MS, Yu EW, Lee H, Neer RM, Schindler E, Taylor AP, Cheston E, Bouxsein ML, Finkelstein JS
Differences in skeletal microarchitecture and strength in African-American and white women. J Bone Miner Res. 2013 Oct; 28(10):2177-85.
Differences in skeletal microarchitecture and strength in African-American and white women.
Hsu YH, Xu X, Terwedow HA, Niu T, Hong X, Wu D, Wang L, Brain JD, Bouxsein ML, Cummings SR, Rosen CJ, Xu X
Large-scale genome-wide linkage analysis for loci linked to BMD at different skeletal sites in extreme selected sibships. J Bone Miner Res. 2007 Feb; 22(2):184-94.
Large-scale genome-wide linkage analysis for loci linked to BMD at different skeletal sites in extreme selected sibships.
Boutroy S, Van Rietbergen B, Sornay-Rendu E, Munoz F, Bouxsein ML, Delmas PD
Finite element analysis based on in vivo HR-pQCT images of the distal radius is associated with wrist fracture in postmenopausal women. J Bone Miner Res. 2008 Mar; 23(3):392-9.
Finite element analysis based on in vivo HR-pQCT images of the distal radius is associated with wrist fracture in postmenopausal women.
Jones MD, Liu JC, Barthel TK, Hussain S, Lovria E, Cheng D, Schoonmaker JA, Mulay S, Ayers DC, Bouxsein ML, Stein GS, Mukherjee S, Lian JB
Clinical cancer research : an official journal of the American Association for Cancer Research
A proteasome inhibitor, bortezomib, inhibits breast cancer growth and reduces osteolysis by downregulating metastatic genes. Clin Cancer Res. 2010 Oct 15; 16(20):4978-89.
A proteasome inhibitor, bortezomib, inhibits breast cancer growth and reduces osteolysis by downregulating metastatic genes.
Rizzoli R, Akesson K, Bouxsein M, Kanis JA, Napoli N, Papapoulos S, Reginster JY, Cooper C
Subtrochanteric fractures after long-term treatment with bisphosphonates: a European Society on Clinical and Economic Aspects of Osteoporosis and Osteoarthritis, and International Osteoporosis Foundation Working Group Report. Osteoporos Int. 2011 Feb; 22(2):373-90.
Subtrochanteric fractures after long-term treatment with bisphosphonates: a European Society on Clinical and Economic Aspects of Osteoporosis and Osteoarthritis, and International Osteoporosis Foundation Working Group Report.
Ellman R, Spatz J, Cloutier A, Palme R, Christiansen BA, Bouxsein ML
Partial reductions in mechanical loading yield proportional changes in bone density, bone architecture, and muscle mass. J Bone Miner Res. 2013 Apr; 28(4):875-85.
Partial reductions in mechanical loading yield proportional changes in bone density, bone architecture, and muscle mass.
Spatz JM, Fields EE, Yu EW, Divieti Pajevic P, Bouxsein ML, Sibonga JD, Zwart SR, Smith SM
Serum sclerostin increases in healthy adult men during bed rest. J Clin Endocrinol Metab. 2012 Sep; 97(9):E1736-40.
Serum sclerostin increases in healthy adult men during bed rest.
Anderson DE, D'Agostino JM, Bruno AG, Demissie S, Kiel DP, Bouxsein ML
Variations of CT-based trunk muscle attenuation by age, sex, and specific muscle. J Gerontol A Biol Sci Med Sci. 2013 Mar; 68(3):317-23.
Variations of CT-based trunk muscle attenuation by age, sex, and specific muscle.
Effects of Denosumab and Teriparatide Transitions on Bone Microarchitecture and Estimated Strength: the DATA-Switch HR-pQCT study. J Bone Miner Res. 2017 Oct; 32(10):2001-2009.
Effects of Denosumab and Teriparatide Transitions on Bone Microarchitecture and Estimated Strength: the DATA-Switch HR-pQCT study.
Le PT, Bishop KA, Maridas DE, Motyl KJ, Brooks DJ, Nagano K, Baron R, Bouxsein ML, Rosen CJ
Spontaneous mutation of Dock7 results in lower trabecular bone mass and impaired periosteal expansion in aged female Misty mice. Bone. 2017 Dec; 105:103-114.
Spontaneous mutation of Dock7 results in lower trabecular bone mass and impaired periosteal expansion in aged female Misty mice.
Silva PPB, Amlashi FG, Yu EW, Pulaski-Liebert KJ, Gerweck AV, Fazeli PK, Lawson E, Nachtigall LB, Biller BMK, Miller KK, Klibanski A, Bouxsein M, Tritos NA
Bone microarchitecture and estimated bone strength in men with active acromegaly. Eur J Endocrinol. 2017 Nov; 177(5):409-420.
Bone microarchitecture and estimated bone strength in men with active acromegaly.
Lorbergs AL, Murabito JM, Jarraya M, Guermazi A, Allaire BT, Yang L, Kiel DP, Cupples LA, Bouxsein ML, Travison TG, Samelson EJ
Journal of the American Geriatrics Society
Thoracic Kyphosis and Physical Function: The Framingham Study. J Am Geriatr Soc. 2017 Oct; 65(10):2257-2264.
Thoracic Kyphosis and Physical Function: The Framingham Study.
Popp KL, Hughes JM, Martinez-Betancourt A, Scott M, Turkington V, Caksa S, Guerriere KI, Ackerman KE, Xu C, Unnikrishnan G, Reifman J, Bouxsein ML
Bone mass, microarchitecture and strength are influenced by race/ethnicity in young adult men and women. Bone. 2017 Oct; 103:200-208.
Bone mass, microarchitecture and strength are influenced by race/ethnicity in young adult men and women.
Roberts BJ, Thrall E, Muller JA, Bouxsein ML
Comparison of hip fracture risk prediction by femoral aBMD to experimentally measured factor of risk. Bone. 2010 Mar; 46(3):742-6.
Comparison of hip fracture risk prediction by femoral aBMD to experimentally measured factor of risk.
Mechanisms Underlying Diabetic Skeletal Fragility
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Effect of local density changes on the failure load of the proximal femur.
Exercise maintains bone mass, but do people maintain exercise? J Bone Miner Res. 2001 Feb; 16(2):202-5.
Exercise maintains bone mass, but do people maintain exercise?
Mechanisms of osteoporosis therapy: a bone strength perspective. Clin Cornerstone. 2003; Suppl 2:S13-21.
Mechanisms of osteoporosis therapy: a bone strength perspective.
Bouxsein ML, Kaufman J, Tosi L, Cummings S, Lane J, Johnell O
The Journal of the American Academy of Orthopaedic Surgeons
Recommendations for optimal care of the fragility fracture patient to reduce the risk of future fracture. J Am Acad Orthop Surg. 2004 Nov-Dec; 12(6):385-95.
Recommendations for optimal care of the fragility fracture patient to reduce the risk of future fracture.
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Contribution of trochanteric soft tissues to fall force estimates, the factor of risk, and prediction of hip fracture risk. J Bone Miner Res. 2007 Jun; 22(6):825-31.
Contribution of trochanteric soft tissues to fall force estimates, the factor of risk, and prediction of hip fracture risk.
Samelson EJ, Demissie S, Cupples LA, Zhang X, Xu H, Liu CT, Boyd SK, McLean RR, Broe KE, Kiel DP, Bouxsein ML
Diabetes and Deficits in Cortical Bone Density, Microarchitecture, and Bone Size: Framingham HR-pQCT Study. J Bone Miner Res. 2018 01; 33(1):54-62.
Diabetes and Deficits in Cortical Bone Density, Microarchitecture, and Bone Size: Framingham HR-pQCT Study.
Pearsall RS, Canalis E, Cornwall-Brady M, Underwood KW, Haigis B, Ucran J, Kumar R, Pobre E, Grinberg A, Werner ED, Glatt V, Stadmeyer L, Smith D, Seehra J, Bouxsein ML
A soluble activin type IIA receptor induces bone formation and improves skeletal integrity. Proc Natl Acad Sci U S A. 2008 May 13; 105(19):7082-7.
A soluble activin type IIA receptor induces bone formation and improves skeletal integrity.
O'Brien CA, Plotkin LI, Galli C, Goellner JJ, Gortazar AR, Allen MR, Robling AG, Bouxsein M, Schipani E, Turner CH, Jilka RL, Weinstein RS, Manolagas SC, Bellido T
Control of bone mass and remodeling by PTH receptor signaling in osteocytes. PLoS One. 2008 Aug 13; 3(8):e2942.
Control of bone mass and remodeling by PTH receptor signaling in osteocytes.
Pierroz DD, Rufo A, Bianchi EN, Glatt V, Capulli M, Rucci N, Cavat F, Rizzoli R, Teti A, Bouxsein ML, Ferrari SL
Beta-Arrestin2 regulates RANKL and ephrins gene expression in response to bone remodeling in mice. J Bone Miner Res. 2009 May; 24(5):775-84.
Beta-Arrestin2 regulates RANKL and ephrins gene expression in response to bone remodeling in mice.
Yakar S, Canalis E, Sun H, Mejia W, Kawashima Y, Nasser P, Courtland HW, Williams V, Bouxsein M, Rosen C, Jepsen KJ
Serum IGF-1 determines skeletal strength by regulating subperiosteal expansion and trait interactions. J Bone Miner Res. 2009 Aug; 24(8):1481-92.
Serum IGF-1 determines skeletal strength by regulating subperiosteal expansion and trait interactions.
Borah B, Dufresne T, Nurre J, Phipps R, Chmielewski P, Wagner L, Lundy M, Bouxsein M, Zebaze R, Seeman E
Risedronate reduces intracortical porosity in women with osteoporosis. J Bone Miner Res. 2010 Jan; 25(1):41-7.
Risedronate reduces intracortical porosity in women with osteoporosis.
Pozzi S, Vallet S, Mukherjee S, Cirstea D, Vaghela N, Santo L, Rosen E, Ikeda H, Okawa Y, Kiziltepe T, Schoonmaker J, Xie W, Hideshima T, Weller E, Bouxsein ML, Munshi NC, Anderson KC, Raje N
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High-dose zoledronic acid impacts bone remodeling with effects on osteoblastic lineage and bone mechanical properties.
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Determinants of the mechanical behavior of human lumbar vertebrae after simulated mild fracture.
Bone marrow influences quantitative ultrasound measurements in human cancellous bone. Ultrasound Med Biol. 2002 Mar; 28(3):369-75.
Bone marrow influences quantitative ultrasound measurements in human cancellous bone.
Bouxsein ML, Turek TJ, Blake CA, D'Augusta D, Li X, Stevens M, Seeherman HJ, Wozney JM
Recombinant human bone morphogenetic protein-2 accelerates healing in a rabbit ulnar osteotomy model. J Bone Joint Surg Am. 2001 Aug; 83(8):1219-30.
Recombinant human bone morphogenetic protein-2 accelerates healing in a rabbit ulnar osteotomy model.
Black DM, Greenspan SL, Ensrud KE, Palermo L, McGowan JA, Lang TF, Garnero P, Bouxsein ML, Bilezikian JP, Rosen CJ
The effects of parathyroid hormone and alendronate alone or in combination in postmenopausal osteoporosis. N Engl J Med. 2003 Sep 25; 349(13):1207-15.
The effects of parathyroid hormone and alendronate alone or in combination in postmenopausal osteoporosis.
Thomas T, Feron JM, Delmas PD, Kaufman J, Tosi L, Cummings S, Lane J, Johnell O, Bouxsein ML
Revue de chirurgie orthopedique et reparatrice de l'appareil moteur
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[Optimal management of patients with stress fractures and the role of the orthopedic surgeon in reducing the risk of new fractures].
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Impact of seafood and fruit consumption on bone mineral density.
Bone geometry and skeletal fragility. Curr Osteoporos Rep. 2006 Jun; 4(2):49-56.
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Predicting the failure load of the distal radius.
Bonner FJ, Sinaki M, Grabois M, Shipp KM, Lane JM, Lindsay R, Gold DT, Cosman F, Bouxsein ML, Weinstein JN, Gallagher RM, Melton LJ, Salcido RS, Gordon SL
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Health professional's guide to rehabilitation of the patient with osteoporosis.
Li RH, Bouxsein ML, Blake CA, D'Augusta D, Kim H, Li XJ, Wozney JM, Seeherman HJ
rhBMP-2 injected in a calcium phosphate paste (alpha-BSM) accelerates healing in the rabbit ulnar osteotomy model. J Orthop Res. 2003 Nov; 21(6):997-1004.
rhBMP-2 injected in a calcium phosphate paste (alpha-BSM) accelerates healing in the rabbit ulnar osteotomy model.
Yakar S, Rosen CJ, Bouxsein ML, Sun H, Mejia W, Kawashima Y, Wu Y, Emerton K, Williams V, Jepsen K, Schaffler MB, Majeska RJ, Gavrilova O, Gutierrez M, Hwang D, Pennisi P, Frystyk J, Boisclair Y, Pintar J, Jasper H, Domene H, Cohen P, Clemmons D, LeRoith D
Serum complexes of insulin-like growth factor-1 modulate skeletal integrity and carbohydrate metabolism. FASEB J. 2009 Mar; 23(3):709-19.
Serum complexes of insulin-like growth factor-1 modulate skeletal integrity and carbohydrate metabolism.
Rozental TD, Vazquez MA, Chacko AT, Ayogu N, Bouxsein ML
Comparison of radiographic fracture healing in the distal radius for patients on and off bisphosphonate therapy. J Hand Surg Am. 2009 Apr; 34(4):595-602.
Comparison of radiographic fracture healing in the distal radius for patients on and off bisphosphonate therapy.
DeMambro VE, Clemmons DR, Horton LG, Bouxsein ML, Wood TL, Beamer WG, Canalis E, Rosen CJ
Gender-specific changes in bone turnover and skeletal architecture in igfbp-2-null mice. Endocrinology. 2008 May; 149(5):2051-61.
Gender-specific changes in bone turnover and skeletal architecture in igfbp-2-null mice.
Black DM, Bouxsein ML, Marshall LM, Cummings SR, Lang TF, Cauley JA, Ensrud KE, Nielson CM, Orwoll ES
Proximal femoral structure and the prediction of hip fracture in men: a large prospective study using QCT. J Bone Miner Res. 2008 Aug; 23(8):1326-33.
Proximal femoral structure and the prediction of hip fracture in men: a large prospective study using QCT.
Rozental TD, Johannesdottir F, Kempland KC, Bouxsein ML
Characterization of trabecular bone microstructure in premenopausal women with distal radius fractures. Osteoporos Int. 2018 02; 29(2):409-419.
Characterization of trabecular bone microstructure in premenopausal women with distal radius fractures.
Ackerman KE, Putman M, Guereca G, Taylor AP, Pierce L, Herzog DB, Klibanski A, Bouxsein M, Misra M
Cortical microstructure and estimated bone strength in young amenorrheic athletes, eumenorrheic athletes and non-athletes. Bone. 2012 Oct; 51(4):680-7.
Cortical microstructure and estimated bone strength in young amenorrheic athletes, eumenorrheic athletes and non-athletes.
Burghardt AJ, Pialat JB, Kazakia GJ, Boutroy S, Engelke K, Patsch JM, Valentinitsch A, Liu D, Szabo E, Bogado CE, Zanchetta MB, McKay HA, Shane E, Boyd SK, Bouxsein ML, Chapurlat R, Khosla S, Majumdar S
Multicenter precision of cortical and trabecular bone quality measures assessed by high-resolution peripheral quantitative computed tomography. J Bone Miner Res. 2013 Mar; 28(3):524-36.
Multicenter precision of cortical and trabecular bone quality measures assessed by high-resolution peripheral quantitative computed tomography.
Bone quality: where do we go from here? Osteoporos Int. 2003 Sep; 14 Suppl 5:S118-27.
Rozental TD, Walley KC, Demissie S, Caksa S, Martinez-Betancourt A, Parker AM, Tsai JN, Yu EW, Bouxsein ML
Bone Material Strength Index as Measured by Impact Microindentation in Postmenopausal Women With Distal Radius and Hip Fractures. J Bone Miner Res. 2018 04; 33(4):621-626.
Bone Material Strength Index as Measured by Impact Microindentation in Postmenopausal Women With Distal Radius and Hip Fractures.
Mitchell DM, Caksa S, Yuan A, Bouxsein ML, Misra M, Burnett-Bowie SM
Trabecular Bone Morphology Correlates With Skeletal Maturity and Body Composition in Healthy Adolescent Girls. J Clin Endocrinol Metab. 2018 01 01; 103(1):336-345.
Trabecular Bone Morphology Correlates With Skeletal Maturity and Body Composition in Healthy Adolescent Girls.
Anderson DE, Mannen EM, Tromp R, Wong BM, Sis HL, Cadel ES, Friis EA, Bouxsein ML
The rib cage reduces intervertebral disc pressures in cadaveric thoracic spines by sharing loading under applied dynamic moments. J Biomech. 2018 03 21; 70:262-266.
The rib cage reduces intervertebral disc pressures in cadaveric thoracic spines by sharing loading under applied dynamic moments.
Bouxsein ML, Pierroz DD, Glatt V, Goddard DS, Cavat F, Rizzoli R, Ferrari SL
beta-Arrestin2 regulates the differential response of cortical and trabecular bone to intermittent PTH in female mice. J Bone Miner Res. 2005 Apr; 20(4):635-43.
beta-Arrestin2 regulates the differential response of cortical and trabecular bone to intermittent PTH in female mice.
Melton LJ, Riggs BL, van Lenthe GH, Achenbach SJ, Müller R, Bouxsein ML, Amin S, Atkinson EJ, Khosla S
Contribution of in vivo structural measurements and load/strength ratios to the determination of forearm fracture risk in postmenopausal women. J Bone Miner Res. 2007 Sep; 22(9):1442-8.
Contribution of in vivo structural measurements and load/strength ratios to the determination of forearm fracture risk in postmenopausal women.
Karasik D, Demissie S, Lu D, Broe KE, Boyd SK, Liu CT, Hsu YH, Bouxsein ML, Kiel DP
Bone Strength Estimated by Micro-Finite Element Analysis (µFEA) Is Heritable and Shares Genetic Predisposition With Areal BMD: The Framingham Study. J Bone Miner Res. 2017 Nov; 32(11):2151-2156.
Bone Strength Estimated by Micro-Finite Element Analysis (µFEA) Is Heritable and Shares Genetic Predisposition With Areal BMD: The Framingham Study.
Rozental TD, Johannesdottir F, Walley KC, Bouxsein ML
Correction to: Characterization of trabecular bone microstructure in premenopausal women with distal radius fractures. Osteoporos Int. 2018 01; 29(1):263.
Correction to: Characterization of trabecular bone microstructure in premenopausal women with distal radius fractures.
Technology insight: noninvasive assessment of bone strength in osteoporosis. Nat Clin Pract Rheumatol. 2008 Jun; 4(6):310-8.
Technology insight: noninvasive assessment of bone strength in osteoporosis.
Einhorn TA, Majeska RJ, Mohaideen A, Kagel EM, Bouxsein ML, Turek TJ, Wozney JM
A single percutaneous injection of recombinant human bone morphogenetic protein-2 accelerates fracture repair. J Bone Joint Surg Am. 2003 Aug; 85(8):1425-35.
A single percutaneous injection of recombinant human bone morphogenetic protein-2 accelerates fracture repair.
Kim YM, Demissie S, Eisenberg R, Samelson EJ, Kiel DP, Bouxsein ML
Intra-and inter-reader reliability of semi-automated quantitative morphometry measurements and vertebral fracture assessment using lateral scout views from computed tomography. Osteoporos Int. 2011 Oct; 22(10):2677-88.
Intra-and inter-reader reliability of semi-automated quantitative morphometry measurements and vertebral fracture assessment using lateral scout views from computed tomography.
Hsu YH, Venners SA, Terwedow HA, Feng Y, Niu T, Li Z, Laird N, Brain JD, Cummings SR, Bouxsein ML, Rosen CJ, Xu X
The American journal of clinical nutrition
Relation of body composition, fat mass, and serum lipids to osteoporotic fractures and bone mineral density in Chinese men and women. Am J Clin Nutr. 2006 Jan; 83(1):146-54.
Relation of body composition, fat mass, and serum lipids to osteoporotic fractures and bone mineral density in Chinese men and women.
Kostenuik PJ, Ferrari S, Pierroz D, Bouxsein M, Morony S, Warmington KS, Adamu S, Geng Z, Grisanti M, Shalhoub V, Martin S, Biddlecome G, Shimamoto G, Boone T, Shen V, Lacey D
Infrequent delivery of a long-acting PTH-Fc fusion protein has potent anabolic effects on cortical and cancellous bone. J Bone Miner Res. 2007 Oct; 22(10):1534-47.
Infrequent delivery of a long-acting PTH-Fc fusion protein has potent anabolic effects on cortical and cancellous bone.
McManus JF, Davey RA, Maclean HE, Doust EA, Chiu WS, Sims NA, Bouxsein ML, Glatt V, Zajac JD, Danks JA
Intermittent Fugu parathyroid hormone 1 (1-34) is an anabolic bone agent in young male rats and osteopenic ovariectomized rats. Bone. 2008 Jun; 42(6):1164-74.
Intermittent Fugu parathyroid hormone 1 (1-34) is an anabolic bone agent in young male rats and osteopenic ovariectomized rats.
Engelke K, Adams JE, Armbrecht G, Augat P, Bogado CE, Bouxsein ML, Felsenberg D, Ito M, Prevrhal S, Hans DB, Lewiecki EM
Clinical use of quantitative computed tomography and peripheral quantitative computed tomography in the management of osteoporosis in adults: the 2007 ISCD Official Positions. J Clin Densitom. 2008 Jan-Mar; 11(1):123-62.
Clinical use of quantitative computed tomography and peripheral quantitative computed tomography in the management of osteoporosis in adults: the 2007 ISCD Official Positions.
Kirmani S, Christen D, van Lenthe GH, Fischer PR, Bouxsein ML, McCready LK, Melton LJ, Riggs BL, Amin S, Müller R, Khosla S
Bone structure at the distal radius during adolescent growth. J Bone Miner Res. 2009 Jun; 24(6):1033-42.
Bone structure at the distal radius during adolescent growth.
Quantifying the material and structural determinants of bone strength. Best Pract Res Clin Rheumatol. 2009 Dec; 23(6):741-53.
Quantifying the material and structural determinants of bone strength.
Considerations for development of surrogate endpoints for antifracture efficacy of new treatments in osteoporosis: a perspective. J Bone Miner Res. 2008 Aug; 23(8):1155-67.
Considerations for development of surrogate endpoints for antifracture efficacy of new treatments in osteoporosis: a perspective.
Roux JP, Wegrzyn J, Arlot ME, Guyen O, Delmas PD, Chapurlat R, Bouxsein ML
Contribution of trabecular and cortical components to biomechanical behavior of human vertebrae: an ex vivo study. J Bone Miner Res. 2010 Feb; 25(2):356-61.
Contribution of trabecular and cortical components to biomechanical behavior of human vertebrae: an ex vivo study.
Samelson EJ, Christiansen BA, Demissie S, Broe KE, Zhou Y, Meng CA, Yu W, Cheng X, O'Donnell CJ, Hoffmann U, Genant HK, Kiel DP, Bouxsein ML
Reliability of vertebral fracture assessment using multidetector CT lateral scout views: the Framingham Osteoporosis Study. Osteoporos Int. 2011 Apr; 22(4):1123-31.
Reliability of vertebral fracture assessment using multidetector CT lateral scout views: the Framingham Osteoporosis Study.
Guo J, Liu M, Yang D, Bouxsein ML, Thomas CC, Schipani E, Bringhurst FR, Kronenberg HM
Phospholipase C signaling via the parathyroid hormone (PTH)/PTH-related peptide receptor is essential for normal bone responses to PTH. Endocrinology. 2010 Aug; 151(8):3502-13.
Phospholipase C signaling via the parathyroid hormone (PTH)/PTH-related peptide receptor is essential for normal bone responses to PTH.
Bone structure and fracture risk: do they go arm in arm? J Bone Miner Res. 2011 Jul; 26(7):1389-91.
Bone structure and fracture risk: do they go arm in arm?
Bauer DC, Black DM, Bouxsein ML, Lui LY, Cauley JA, de Papp AE, Grauer A, Khosla S, McCulloch CE, Eastell R
Treatment-Related Changes in Bone Turnover and Fracture Risk Reduction in Clinical Trials of Anti-Resorptive Drugs: A Meta-Regression. J Bone Miner Res. 2018 04; 33(4):634-642.
Treatment-Related Changes in Bone Turnover and Fracture Risk Reduction in Clinical Trials of Anti-Resorptive Drugs: A Meta-Regression.
Betz VM, Betz OB, Glatt V, Gerstenfeld LC, Einhorn TA, Bouxsein ML, Vrahas MS, Evans CH
Healing of segmental bone defects by direct percutaneous gene delivery: effect of vector dose. Hum Gene Ther. 2007 Oct; 18(10):907-15.
Healing of segmental bone defects by direct percutaneous gene delivery: effect of vector dose.
Berman SD, Calo E, Landman AS, Danielian PS, Miller ES, West JC, Fonhoue BD, Caron A, Bronson R, Bouxsein ML, Mukherjee S, Lees JA
Metastatic osteosarcoma induced by inactivation of Rb and p53 in the osteoblast lineage. Proc Natl Acad Sci U S A. 2008 Aug 19; 105(33):11851-6.
Metastatic osteosarcoma induced by inactivation of Rb and p53 in the osteoblast lineage.
Portero-Muzy NR, Chavassieux PM, Bouxsein ML, Gineyts E, Garnero P, Chapurlat RD
Early effects of zoledronic acid and teriparatide on bone microarchitecture, remodeling and collagen crosslinks: comparison between iliac crest and lumbar vertebra in ewes. Bone. 2012 Oct; 51(4):714-9.
Early effects of zoledronic acid and teriparatide on bone microarchitecture, remodeling and collagen crosslinks: comparison between iliac crest and lumbar vertebra in ewes.
Faje AT, Karim L, Taylor A, Lee H, Miller KK, Mendes N, Meenaghan E, Goldstein MA, Bouxsein ML, Misra M, Klibanski A
Adolescent girls with anorexia nervosa have impaired cortical and trabecular microarchitecture and lower estimated bone strength at the distal radius. J Clin Endocrinol Metab. 2013 May; 98(5):1923-9.
Adolescent girls with anorexia nervosa have impaired cortical and trabecular microarchitecture and lower estimated bone strength at the distal radius.
Fazeli PK, Ackerman KE, Pierce L, Guereca G, Bouxsein M, Misra M
Sclerostin and Pref-1 have differential effects on bone mineral density and strength parameters in adolescent athletes compared with non-athletes. Osteoporos Int. 2013 Sep; 24(9):2433-40.
Sclerostin and Pref-1 have differential effects on bone mineral density and strength parameters in adolescent athletes compared with non-athletes.
New approaches for interpreting projected bone densitometry data. J Bone Miner Res. 1992 Feb; 7(2):137-45.
New approaches for interpreting projected bone densitometry data.
Babij P, Zhao W, Small C, Kharode Y, Yaworsky PJ, Bouxsein ML, Reddy PS, Bodine PV, Robinson JA, Bhat B, Marzolf J, Moran RA, Bex F
High bone mass in mice expressing a mutant LRP5 gene. J Bone Miner Res. 2003 Jun; 18(6):960-74.
High bone mass in mice expressing a mutant LRP5 gene.
Bredella MA, Lin E, Gerweck AV, Landa MG, Thomas BJ, Torriani M, Bouxsein ML, Miller KK
Determinants of bone microarchitecture and mechanical properties in obese men. J Clin Endocrinol Metab. 2012 Nov; 97(11):4115-22.
Determinants of bone microarchitecture and mechanical properties in obese men.