Seidman, Christine
completed student projects: Mutations in ALPK3 underlie neonatal onset of cardiac hypertrophy
eCommons Login: CES5
first name: Christine
last name: Seidman
coauthor of: Seidman, Jonathan
coauthor of: Morton, Sarah
coauthor of: Ho, Carolyn
coauthor of: Wakimoto, Hiroko
coauthor of: Kim, Yuri
full name: Christine Edry Seidman, M.D.
has faculty rank: Full Professor
has network: selected publications
has network: research areas
has network: coauthor of
has network: similar to
latitude: 42.33837200000000
longitude: -71.10326900000000
Person ID: 29608
person in primary position: Thomas W. Smith Professor of Medicine
physical neighbor: Aikawa, Elena
physical neighbor: Croce, Kevin
physical neighbor: Feinberg, Mark
physical neighbor: Handy, Diane
physical neighbor: Leopold, Jane
similar to: Ho, Carolyn
similar to: Seidman, Jonathan
similar to: Solomon, Scott
similar to: Lakdawala, Neal
similar to: Alkuraya, Fowzan
type: Agent
type: Person
selected publications: Authorship 1819491
selected publications: Authorship 1846542
selected publications: Authorship 1780137
selected publications: Authorship 1753000
selected publications: Authorship 1811299
selected publications: Authorship 1823745
selected publications: Authorship 1777222
selected publications: Authorship 1747507
selected publications: Authorship 1747511
selected publications: Authorship 1742595
selected publications: Authorship 1740295
selected publications: Authorship 1743022
selected publications: Authorship 1740838
selected publications: Authorship 1738957
selected publications: Authorship 1739018
selected publications: Authorship 1736352
selected publications: Authorship 1730126
selected publications: Authorship 1736089
selected publications: Authorship 1729355
selected publications: Authorship 1723473
selected publications: Authorship 1717043
selected publications: Authorship 1720444
selected publications: Authorship 1709561
selected publications: Authorship 1652909
selected publications: Authorship 1706731
selected publications: Authorship 1701632
selected publications: Authorship 1685210
selected publications: Authorship 1684723
selected publications: Authorship 1685378
selected publications: Authorship 1665046
selected publications: Authorship 1664522
selected publications: Authorship 1656796
selected publications: Authorship 1651110
selected publications: Authorship 1641625
selected publications: Authorship 1641611
selected publications: Authorship 1629101
selected publications: Authorship 1638414
selected publications: Authorship 1632762
selected publications: Authorship 1631053
selected publications: Authorship 1627515
selected publications: Authorship 1719708
selected publications: Authorship 1608722
selected publications: Authorship 1591744
selected publications: Authorship 1684745
selected publications: Authorship 1630836
selected publications: Authorship 1583863
selected publications: Authorship 1591715
selected publications: Authorship 1584581

completed student projects
tag name: catalyst:advisorInMentoringCompletedStudentProject
type: ObjectProperty

eCommons Login
tag name: catalyst:eCommonsLogin
type: DatatypeProperty

Mentoring - Completed Student Project
type: Class

coauthor of
tag name: prns:coAuthorOf
type: ObjectProperty

end date
tag name: prns:endDate
type: DatatypeProperty

Faculty Rank
type: Class

full name
tag name: prns:fullName
type: DatatypeProperty

author list
tag name: prns:hasAuthorList
type: DatatypeProperty

has faculty rank
tag name: prns:hasFacultyRank
type: ObjectProperty

has network
tag name: prns:hasNetwork
type: ObjectProperty

published in
tag name: prns:hasPublicationVenue
type: DatatypeProperty

information resource reference
tag name: prns:informationResourceReference
type: DatatypeProperty

is primary position
tag name: prns:isPrimaryPosition
type: DatatypeProperty

latitude
tag name: prns:latitude
type: DatatypeProperty

longitude
tag name: prns:longitude
type: DatatypeProperty

photo
tag name: prns:mainImage
type: ObjectProperty

maximum weight
tag name: prns:maxWeight
type: DatatypeProperty

journal title abbreviation
tag name: prns:medlineTA
type: DatatypeProperty

MeSH DescriptorUI
tag name: prns:meshDescriptorUI
type: DatatypeProperty

MeSH semantic group name
tag name: prns:meshSemanticGroupName
type: DatatypeProperty

minimum weight
tag name: prns:minWeight
type: DatatypeProperty

number of authors
tag name: prns:numberOfAuthors
type: DatatypeProperty

number of connections
tag name: prns:numberOfConnections
type: DatatypeProperty

number of publications
tag name: prns:numberOfPublications
type: DatatypeProperty

Person ID
tag name: prns:personId
type: DatatypeProperty

person in primary position
tag name: prns:personInPrimaryPosition
type: ObjectProperty

physical neighbor
tag name: prns:physicalNeighborOf
type: ObjectProperty

position in department
tag name: prns:positionInDepartment
type: ObjectProperty

position in division
tag name: prns:positionInDivision
type: ObjectProperty

predicate node
tag name: prns:predicateNode
type: ObjectProperty

principal investigator name
tag name: prns:principalInvestigatorName
type: DatatypeProperty

publication date
tag name: prns:publicationDate
type: DatatypeProperty

similar to
tag name: prns:similarTo
type: ObjectProperty

sort order
tag name: prns:sortOrder
type: DatatypeProperty

start date
tag name: prns:startDate
type: DatatypeProperty

uniqueness weight
tag name: prns:uniquenessWeight
type: DatatypeProperty

year
tag name: prns:year
type: DatatypeProperty

Academic Article
type: Class

Article
type: Class

Document
type: Class

PubMed Identifier
tag name: bibo:pmid
type: DatatypeProperty

Address
type: Class

address line 1
tag name: vivo:address1
type: DatatypeProperty

address line 2
tag name: vivo:address2
type: DatatypeProperty

address line 3
tag name: vivo:address3
type: DatatypeProperty

city
tag name: vivo:addressCity
type: DatatypeProperty
type: FunctionalProperty

postal code
tag name: vivo:addressPostalCode
type: DatatypeProperty
type: FunctionalProperty

state or province
tag name: vivo:addressState
type: DatatypeProperty
type: FunctionalProperty

selected publications
tag name: vivo:authorInAuthorship
type: ObjectProperty

author rank in publication
tag name: vivo:authorRank
type: DatatypeProperty
type: FunctionalProperty

Authorship
type: Class

Department
type: Class

Division
type: Class

Grant
type: Class

research areas
tag name: vivo:hasResearchArea
type: ObjectProperty

research activities
tag name: vivo:hasResearcherRole
type: ObjectProperty

HR job title
tag name: vivo:hrJobTitle
type: DatatypeProperty

Information Resource
type: Class

linked author
tag name: vivo:linkedAuthor
type: ObjectProperty

linked information resource
tag name: vivo:linkedInformationResource
type: ObjectProperty

mailing address
tag name: vivo:mailingAddress
type: ObjectProperty

middle name or initial
tag name: vivo:middleName
type: DatatypeProperty
type: FunctionalProperty

overview
tag name: vivo:overview
type: DatatypeProperty
type: FunctionalProperty

positions
tag name: vivo:personInPosition
type: ObjectProperty

phone
tag name: vivo:phoneNumber
type: DatatypeProperty

Position
type: Class

position in organization
tag name: vivo:positionInOrganization
type: ObjectProperty

preferred title
tag name: vivo:preferredTitle
type: DatatypeProperty
type: FunctionalProperty

Researcher Role
type: Class

researcher role of
tag name: vivo:researcherRoleOf
type: ObjectProperty

contributes to
tag name: vivo:roleContributesTo
type: ObjectProperty

sponsor award id
tag name: vivo:sponsorAwardId
type: DatatypeProperty
type: FunctionalProperty

predicate
tag name: rdf:predicate
type: ObjectProperty

type
tag name: rdf:type
type: ObjectProperty

label
tag name: rdfs:label
type: DatatypeProperty

Concept
type: Class

Agent
type: Class

first name
tag name: foaf:firstName
type: DatatypeProperty
type: FunctionalProperty

last name
tag name: foaf:lastName
type: DatatypeProperty
type: FunctionalProperty

Organization
type: Class

Person
type: Class

Haploinsufficiency of MSX1: a mechanism for selective tooth agenesis.
PubMed Identifier: 9742121
author list: Hu G, Vastardis H, Bendall AJ, Wang Z, Logan M, Zhang H, Nelson C, Stein S, Greenfield N, Seidman CE, Seidman JG, Abate-Shen C
published in: Molecular and cellular biology
information resource reference: Haploinsufficiency of MSX1: a mechanism for selective tooth agenesis. Mol Cell Biol. 1998 Oct; 18(10):6044-51.
journal title abbreviation: Mol Cell Biol
publication date: 1998-10-01T00:00:00
year: 1998
type: Academic Article
type: Article
type: Document
type: Information Resource

https://connects.catalyst.harvard.edu/Profiles/profile/1000100
PubMed Identifier: 9760303
author list: Maron BJ, Moller JH, Seidman CE, Vincent GM, Dietz HC, Moss AJ, Towbin JA, Sondheimer HM, Pyeritz RE, McGee G, Epstein AE
published in: Circulation
information resource reference: Impact of laboratory molecular diagnosis on contemporary diagnostic criteria for genetically transmitted cardiovascular diseases: hypertrophic cardiomyopathy, long-QT syndrome, and marfan syndrome : A statement for healthcare professionals from the councils on clinical cardiology, cardiovascular disease in the young, and basic science, american heart association Circulation. 1998 Oct 06; 98(14):1460-71.
journal title abbreviation: Circulation
publication date: 1998-10-06T00:00:00
year: 1998
type: Academic Article
type: Article
type: Document
type: Information Resource
label: Impact of laboratory molecular diagnosis on contemporary diagnostic criteria for genetically transmitted cardiovascular diseases: hypertrophic cardiomyopathy, long-QT syndrome, and marfan syndrome : A statement for healthcare professionals from the councils on clinical cardiology, cardiovascular disease in the young, and basic science, american heart association

Authorship 100633
type: Authorship
author rank in publication: 9
linked author: Seidman, Christine
linked information resource: Identification, characterization, and chromosomal localization of the human homolog (hES) of ES/130.

Characteristics and prognostic implications of myosin missense mutations in familial hypertrophic cardiomyopathy.
PubMed Identifier: 1552912
author list: Watkins H, Rosenzweig A, Hwang DS, Levi T, McKenna W, Seidman CE, Seidman JG
published in: The New England journal of medicine
information resource reference: Characteristics and prognostic implications of myosin missense mutations in familial hypertrophic cardiomyopathy. N Engl J Med. 1992 Apr 23; 326(17):1108-14.
journal title abbreviation: N Engl J Med
publication date: 1992-04-23T00:00:00
year: 1992
type: Academic Article
type: Article
type: Document
type: Information Resource

Identification of genetic loci associated with paralysis, inflammation and weight loss in mouse experimental autoimmune encephalomyelitis.
PubMed Identifier: 11222494
author list: Encinas JA, Lees MB, Sobel RA, Symonowicz C, Weiner HL, Seidman CE, Seidman JG, Kuchroo VK
published in: International immunology
information resource reference: Identification of genetic loci associated with paralysis, inflammation and weight loss in mouse experimental autoimmune encephalomyelitis. Int Immunol. 2001 Mar; 13(3):257-64.
journal title abbreviation: Int Immunol
publication date: 2001-03-01T00:00:00
year: 2001
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1046718
type: Authorship
author rank in publication: 16
linked author: Seidman, Christine
linked information resource: Robust identification of mosaic variants in congenital heart disease.

Robust identification of mosaic variants in congenital heart disease.
PubMed Identifier: 29417219
author list: Manheimer KB, Richter F, Edelmann LJ, D'Souza SL, Shi L, Shen Y, Homsy J, Boskovski MT, Tai AC, Gorham J, Yasso C, Goldmuntz E, Brueckner M, Lifton RP, Chung WK, Seidman CE, Seidman JG, Gelb BD
published in: Human genetics
information resource reference: Robust identification of mosaic variants in congenital heart disease. Hum Genet. 2018 Feb; 137(2):183-193.
journal title abbreviation: Hum Genet
publication date: 2018-02-07T00:00:00
year: 2018
type: Academic Article
type: Article
type: Document
type: Information Resource

Many roads lead to a broken heart: the genetics of dilated cardiomyopathy.
PubMed Identifier: 11443548
author list: Schönberger J, Seidman CE
published in: American journal of human genetics
information resource reference: Many roads lead to a broken heart: the genetics of dilated cardiomyopathy. Am J Hum Genet. 2001 Aug; 69(2):249-60.
journal title abbreviation: Am J Hum Genet
publication date: 2001-07-06T00:00:00
year: 2001
type: Academic Article
type: Article
type: Document
type: Information Resource

A polymorphic modifier gene alters the hypertrophic response in a murine model of familial hypertrophic cardiomyopathy.
PubMed Identifier: 11708849
author list: Semsarian C, Healey MJ, Fatkin D, Giewat M, Duffy C, Seidman CE, Seidman JG
published in: Journal of molecular and cellular cardiology
information resource reference: A polymorphic modifier gene alters the hypertrophic response in a murine model of familial hypertrophic cardiomyopathy. J Mol Cell Cardiol. 2001 Nov; 33(11):2055-60.
journal title abbreviation: J Mol Cell Cardiol
publication date: 2001-11-01T00:00:00
year: 2001
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1052467
type: Authorship
author rank in publication: 3
linked author: Seidman, Christine
linked information resource: Genetic Pathogenesis of Hypertrophic and Dilated Cardiomyopathy.

Authorship 1050934
type: Authorship
author rank in publication: 15
linked author: Seidman, Christine
linked information resource: Robust identification of deletions in exome and genome sequence data based on clustering of Mendelian errors.

Robust identification of deletions in exome and genome sequence data based on clustering of Mendelian errors.
PubMed Identifier: 29527824
author list: Manheimer KB, Patel N, Richter F, Gorham J, Tai AC, Homsy J, Boskovski MT, Parfenov M, Goldmuntz E, Chung WK, Brueckner M, Tristani-Firouzi M, Srivastava D, Seidman JG, Seidman CE, Gelb BD, Sharp AJ
published in: Human mutation
information resource reference: Robust identification of deletions in exome and genome sequence data based on clustering of Mendelian errors. Hum Mutat. 2018 06; 39(6):870-881.
journal title abbreviation: Hum Mutat
publication date: 2018-03-22T00:00:00
year: 2018
type: Academic Article
type: Article
type: Document
type: Information Resource

Genetic Pathogenesis of Hypertrophic and Dilated Cardiomyopathy.
PubMed Identifier: 29525643
author list: Garfinkel AC, Seidman JG, Seidman CE
published in: Heart failure clinics
information resource reference: Genetic Pathogenesis of Hypertrophic and Dilated Cardiomyopathy. Heart Fail Clin. 2018 Apr; 14(2):139-146.
journal title abbreviation: Heart Fail Clin
publication date: 2018-04-01T00:00:00
year: 2018
type: Academic Article
type: Article
type: Document
type: Information Resource

Divergent pathways mediate the induction of ANF transgenes in neonatal and hypertrophic ventricular myocardium.
PubMed Identifier: 7657806
author list: Knowlton KU, Rockman HA, Itani M, Vovan A, Seidman CE, Chien KR
published in: The Journal of clinical investigation
information resource reference: Divergent pathways mediate the induction of ANF transgenes in neonatal and hypertrophic ventricular myocardium. J Clin Invest. 1995 Sep; 96(3):1311-8.
journal title abbreviation: J Clin Invest
publication date: 1995-09-01T00:00:00
year: 1995
type: Academic Article
type: Article
type: Document
type: Information Resource

A de novo mutation in alpha-tropomyosin that causes hypertrophic cardiomyopathy.
PubMed Identifier: 7729014
author list: Watkins H, Anan R, Coviello DA, Spirito P, Seidman JG, Seidman CE
published in: Circulation
information resource reference: A de novo mutation in alpha-tropomyosin that causes hypertrophic cardiomyopathy. Circulation. 1995 May 01; 91(9):2302-5.
journal title abbreviation: Circulation
publication date: 1995-05-01T00:00:00
year: 1995
type: Academic Article
type: Article
type: Document
type: Information Resource

Mutation in the transcriptional coactivator EYA4 causes dilated cardiomyopathy and sensorineural hearing loss.
PubMed Identifier: 15735644
author list: Schönberger J, Wang L, Shin JT, Kim SD, Depreux FF, Zhu H, Zon L, Pizard A, Kim JB, Macrae CA, Mungall AJ, Seidman JG, Seidman CE
published in: Nature genetics
information resource reference: Mutation in the transcriptional coactivator EYA4 causes dilated cardiomyopathy and sensorineural hearing loss. Nat Genet. 2005 Apr; 37(4):418-22.
journal title abbreviation: Nat Genet
publication date: 2005-02-27T00:00:00
year: 2005
type: Academic Article
type: Article
type: Document
type: Information Resource

A molecular basis for familial hypertrophic cardiomyopathy: a beta cardiac myosin heavy chain gene missense mutation.
PubMed Identifier: 1975517
author list: Geisterfer-Lowrance AA, Kass S, Tanigawa G, Vosberg HP, McKenna W, Seidman CE, Seidman JG
published in: Cell
information resource reference: A molecular basis for familial hypertrophic cardiomyopathy: a beta cardiac myosin heavy chain gene missense mutation. Cell. 1990 Sep 07; 62(5):999-1006.
journal title abbreviation: Cell
publication date: 1990-09-07T00:00:00
year: 1990
type: Academic Article
type: Article
type: Document
type: Information Resource

Somatic events modify hypertrophic cardiomyopathy pathology and link hypertrophy to arrhythmia.
PubMed Identifier: 16332958
author list: Wolf CM, Moskowitz IP, Arno S, Branco DM, Semsarian C, Bernstein SA, Peterson M, Maida M, Morley GE, Fishman G, Berul CI, Seidman CE, Seidman JG
published in: Proceedings of the National Academy of Sciences of the United States of America
information resource reference: Somatic events modify hypertrophic cardiomyopathy pathology and link hypertrophy to arrhythmia. Proc Natl Acad Sci U S A. 2005 Dec 13; 102(50):18123-8.
journal title abbreviation: Proc Natl Acad Sci U S A
publication date: 2005-12-06T00:00:00
year: 2005
type: Academic Article
type: Article
type: Document
type: Information Resource

Spatiotemporal Multi-Omics Mapping Generates a Molecular Atlas of the Aortic Valve and Reveals Networks Driving Disease.
PubMed Identifier: 29588317
author list: Schlotter F, Halu A, Goto S, Blaser MC, Body SC, Lee LH, Higashi H, DeLaughter DM, Hutcheson JD, Vyas P, Pham T, Rogers MA, Sharma A, Seidman CE, Loscalzo J, Seidman JG, Aikawa M, Singh SA, Aikawa E
published in: Circulation
information resource reference: Spatiotemporal Multi-Omics Mapping Generates a Molecular Atlas of the Aortic Valve and Reveals Networks Driving Disease. Circulation. 2018 07 24; 138(4):377-393.
journal title abbreviation: Circulation
publication date: 2018-07-24T00:00:00
year: 2018
type: Academic Article
type: Article
type: Document
type: Information Resource

Autosomal dominant hypocalcaemia caused by a Ca(2+)-sensing receptor gene mutation.
PubMed Identifier: 7874174
author list: Pollak MR, Brown EM, Estep HL, McLaine PN, Kifor O, Park J, Hebert SC, Seidman CE, Seidman JG
published in: Nature genetics
information resource reference: Autosomal dominant hypocalcaemia caused by a Ca(2+)-sensing receptor gene mutation. Nat Genet. 1994 Nov; 8(3):303-7.
journal title abbreviation: Nat Genet
publication date: 1994-11-01T00:00:00
year: 1994
type: Academic Article
type: Article
type: Document
type: Information Resource

Diastolic dysfunction and altered energetics in the alphaMHC403/+ mouse model of familial hypertrophic cardiomyopathy.
PubMed Identifier: 9541509
author list: Spindler M, Saupe KW, Christe ME, Sweeney HL, Seidman CE, Seidman JG, Ingwall JS
published in: The Journal of clinical investigation
information resource reference: Diastolic dysfunction and altered energetics in the alphaMHC403/+ mouse model of familial hypertrophic cardiomyopathy. J Clin Invest. 1998 Apr 15; 101(8):1775-83.
journal title abbreviation: J Clin Invest
publication date: 1998-04-15T00:00:00
year: 1998
type: Academic Article
type: Article
type: Document
type: Information Resource

A gene for hereditary haemorrhagic telangiectasia maps to chromosome 9q3.
PubMed Identifier: 8162076
author list: Shovlin CL, Hughes JM, Tuddenham EG, Temperley I, Perembelon YF, Scott J, Seidman CE, Seidman JG
published in: Nature genetics
information resource reference: A gene for hereditary haemorrhagic telangiectasia maps to chromosome 9q3. Nat Genet. 1994 Feb; 6(2):205-9.
journal title abbreviation: Nat Genet
publication date: 1994-02-01T00:00:00
year: 1994
type: Academic Article
type: Article
type: Document
type: Information Resource

A dinucleotide repeat polymorphism in the human LAMB2 gene on chromosome 1q.
PubMed Identifier: 8364561
author list: Watkins HC, MacRae CA, Thierfelder L, McKenna WJ, Seidman CE, Seidman JG
published in: Human molecular genetics
information resource reference: A dinucleotide repeat polymorphism in the human LAMB2 gene on chromosome 1q. Hum Mol Genet. 1993 Jul; 2(7):1084.
journal title abbreviation: Hum Mol Genet
publication date: 1993-07-01T00:00:00
year: 1993
type: Academic Article
type: Article
type: Document
type: Information Resource

An RNA-seq protocol to identify mRNA expression changes in mouse diaphyseal bone: applications in mice with bone property altering Lrp5 mutations.
PubMed Identifier: 23553928
author list: Ayturk UM, Jacobsen CM, Christodoulou DC, Gorham J, Seidman JG, Seidman CE, Robling AG, Warman ML
published in: Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research
information resource reference: An RNA-seq protocol to identify mRNA expression changes in mouse diaphyseal bone: applications in mice with bone property altering Lrp5 mutations. J Bone Miner Res. 2013 Oct; 28(10):2081-93.
journal title abbreviation: J Bone Miner Res
publication date: 2013-10-01T00:00:00
year: 2013
type: Academic Article
type: Article
type: Document
type: Information Resource

Cardiac myosin binding protein-C is essential for thick-filament stability and flexural rigidity.
PubMed Identifier: 19383471
author list: Nyland LR, Palmer BM, Chen Z, Maughan DW, Seidman CE, Seidman JG, Kreplak L, Vigoreaux JO
published in: Biophysical journal
information resource reference: Cardiac myosin binding protein-C is essential for thick-filament stability and flexural rigidity. Biophys J. 2009 Apr 22; 96(8):3273-80.
journal title abbreviation: Biophys J
publication date: 2009-04-22T00:00:00
year: 2009
type: Academic Article
type: Article
type: Document
type: Information Resource

Dissecting spatio-temporal protein networks driving human heart development and related disorders.
PubMed Identifier: 20571530
author list: Lage K, Møllgård K, Greenway S, Wakimoto H, Gorham JM, Workman CT, Bendsen E, Hansen NT, Rigina O, Roque FS, Wiese C, Christoffels VM, Roberts AE, Smoot LB, Pu WT, Donahoe PK, Tommerup N, Brunak S, Seidman CE, Seidman JG, Larsen LA
published in: Molecular systems biology
information resource reference: Dissecting spatio-temporal protein networks driving human heart development and related disorders. Mol Syst Biol. 2010 Jun 22; 6:381.
journal title abbreviation: Mol Syst Biol
publication date: 2010-06-22T00:00:00
year: 2010
type: Academic Article
type: Article
type: Document
type: Information Resource

Cardiac fibrosis in mice with hypertrophic cardiomyopathy is mediated by non-myocyte proliferation and requires Tgf-ß.
PubMed Identifier: 20811150
author list: Teekakirikul P, Eminaga S, Toka O, Alcalai R, Wang L, Wakimoto H, Nayor M, Konno T, Gorham JM, Wolf CM, Kim JB, Schmitt JP, Molkentin JD, Norris RA, Tager AM, Hoffman SR, Markwald RR, Seidman CE, Seidman JG
published in: The Journal of clinical investigation
information resource reference: Cardiac fibrosis in mice with hypertrophic cardiomyopathy is mediated by non-myocyte proliferation and requires Tgf-ß. J Clin Invest. 2010 Oct; 120(10):3520-9.
journal title abbreviation: J Clin Invest
publication date: 2010-09-01T00:00:00
year: 2010
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1057364
type: Authorship
author rank in publication: 14
linked author: Seidman, Christine
linked information resource: Spatiotemporal Multi-Omics Mapping Generates a Molecular Atlas of the Aortic Valve and Reveals Networks Driving Disease.

Sequencing of TGF-beta pathway genes in familial cases of intracranial aneurysm.
PubMed Identifier: 19299629
author list: Santiago-Sim T, Mathew-Joseph S, Pannu H, Milewicz DM, Seidman CE, Seidman JG, Kim DH
published in: Stroke
information resource reference: Sequencing of TGF-beta pathway genes in familial cases of intracranial aneurysm. Stroke. 2009 May; 40(5):1604-11.
journal title abbreviation: Stroke
publication date: 2009-03-19T00:00:00
year: 2009
type: Academic Article
type: Article
type: Document
type: Information Resource

A classic twin study of external ear malformations, including microtia.
PubMed Identifier: 19759387
author list: Artunduaga MA, Quintanilla-Dieck Mde L, Greenway S, Betensky R, Nicolau Y, Hamdan U, Jarrin P, Osorno G, Brent B, Eavey R, Seidman C, Seidman JG
published in: The New England journal of medicine
information resource reference: A classic twin study of external ear malformations, including microtia. N Engl J Med. 2009 Sep 17; 361(12):1216-8.
journal title abbreviation: N Engl J Med
publication date: 2009-09-17T00:00:00
year: 2009
type: Academic Article
type: Article
type: Document
type: Information Resource

[Using molecular genetics to guide the diagnosis and treatment of hypertrophic cardiomyopathy].
PubMed Identifier: 20193173
author list: Wang LB, Seidman JG, Seidman CE
published in: Zhonghua xin xue guan bing za zhi
information resource reference: [Using molecular genetics to guide the diagnosis and treatment of hypertrophic cardiomyopathy]. Zhonghua Xin Xue Guan Bing Za Zhi. 2009 Dec; 37(12):1063-8.
journal title abbreviation: Zhonghua Xin Xue Guan Bing Za Zhi
publication date: 2009-12-01T00:00:00
year: 2009
type: Academic Article
type: Article
type: Document
type: Information Resource

Narrative review: harnessing molecular genetics for the diagnosis and management of hypertrophic cardiomyopathy.
PubMed Identifier: 20404382
author list: Wang L, Seidman JG, Seidman CE
published in: Annals of internal medicine
information resource reference: Narrative review: harnessing molecular genetics for the diagnosis and management of hypertrophic cardiomyopathy. Ann Intern Med. 2010 Apr 20; 152(8):513-20, W181.
journal title abbreviation: Ann Intern Med
publication date: 2010-04-20T00:00:00
year: 2010
type: Academic Article
type: Article
type: Document
type: Information Resource

Genome-wide assessment for genetic variants associated with ventricular dysfunction after primary coronary artery bypass graft surgery.
PubMed Identifier: 21980348
author list: Fox AA, Pretorius M, Liu KY, Collard CD, Perry TE, Shernan SK, De Jager PL, Hafler DA, Herman DS, DePalma SR, Roden DM, Muehlschlegel JD, Donahue BS, Darbar D, Seidman JG, Body SC, Seidman CE
published in: PloS one
information resource reference: Genome-wide assessment for genetic variants associated with ventricular dysfunction after primary coronary artery bypass graft surgery. PLoS One. 2011; 6(9):e24593.
journal title abbreviation: PLoS One
publication date: 2011-09-30T00:00:00
year: 2011
type: Academic Article
type: Article
type: Document
type: Information Resource

Familial hypertrophic cardiomyopathy: a genetic model of cardiac hypertrophy.
PubMed Identifier: 8541871
author list: Watkins H, Seidman JG, Seidman CE
published in: Human molecular genetics
information resource reference: Familial hypertrophic cardiomyopathy: a genetic model of cardiac hypertrophy. Hum Mol Genet. 1995; 4 Spec No:1721-7.
journal title abbreviation: Hum Mol Genet
publication date: 1995-01-01T00:00:00
year: 1995
type: Academic Article
type: Article
type: Document
type: Information Resource

https://connects.catalyst.harvard.edu/Profiles/profile/1037784
PubMed Identifier: 16567565
author list: Maron BJ, Towbin JA, Thiene G, Antzelevitch C, Corrado D, Arnett D, Moss AJ, Seidman CE, Young JB
published in: Circulation
information resource reference: Contemporary definitions and classification of the cardiomyopathies: an American Heart Association Scientific Statement from the Council on Clinical Cardiology, Heart Failure and Transplantation Committee; Quality of Care and Outcomes Research and Functional Genomics and Translational Biology Interdisciplinary Working Groups; and Council on Epidemiology and Prevention. Circulation. 2006 Apr 11; 113(14):1807-16.
journal title abbreviation: Circulation
publication date: 2006-03-27T00:00:00
year: 2006
type: Academic Article
type: Article
type: Document
type: Information Resource
label: Contemporary definitions and classification of the cardiomyopathies: an American Heart Association Scientific Statement from the Council on Clinical Cardiology, Heart Failure and Transplantation Committee; Quality of Care and Outcomes Research and Functional Genomics and Translational Biology Interdisciplinary Working Groups; and Council on Epidemiology and Prevention.

Novel locus for an inherited cardiomyopathy maps to chromosome 7.
PubMed Identifier: 16651466
author list: Song L, DePalma SR, Kharlap M, Zenovich AG, Cirino A, Mitchell R, McDonough B, Maron BJ, Seidman CE, Seidman JG, Ho CY
published in: Circulation
information resource reference: Novel locus for an inherited cardiomyopathy maps to chromosome 7. Circulation. 2006 May 09; 113(18):2186-92.
journal title abbreviation: Circulation
publication date: 2006-05-01T00:00:00
year: 2006
type: Academic Article
type: Article
type: Document
type: Information Resource

Sarcomere protein gene mutations and inherited heart disease: a beta-cardiac myosin heavy chain mutation causing endocardial fibroelastosis and heart failure.
PubMed Identifier: 17019812
author list: Kamisago M, Schmitt JP, McNamara D, Seidman C, Seidman JG
published in: Novartis Foundation symposium
information resource reference: Sarcomere protein gene mutations and inherited heart disease: a beta-cardiac myosin heavy chain mutation causing endocardial fibroelastosis and heart failure. Novartis Found Symp. 2006; 274:176-89; discussion 189-95, 272-6.
journal title abbreviation: Novartis Found Symp
publication date: 2006-01-01T00:00:00
year: 2006
type: Academic Article
type: Article
type: Document
type: Information Resource

A molecular basis for familial hypertrophic cardiomyopathy: an alpha/beta cardiac myosin heavy chain hybrid gene.
PubMed Identifier: 2144212
author list: Tanigawa G, Jarcho JA, Kass S, Solomon SD, Vosberg HP, Seidman JG, Seidman CE
published in: Cell
information resource reference: A molecular basis for familial hypertrophic cardiomyopathy: an alpha/beta cardiac myosin heavy chain hybrid gene. Cell. 1990 Sep 07; 62(5):991-8.
journal title abbreviation: Cell
publication date: 1990-09-07T00:00:00
year: 1990
type: Academic Article
type: Article
type: Document
type: Information Resource

Introduction of plasmid DNA into cells.
PubMed Identifier: 18429079
author list: Seidman CE, Struhl K
published in: Current protocols in protein science
information resource reference: Introduction of plasmid DNA into cells. Curr Protoc Protein Sci. 2001 May; Appendix 4:4D.
journal title abbreviation: Curr Protoc Protein Sci
publication date: 2001-05-01T00:00:00
year: 2001
type: Academic Article
type: Article
type: Document
type: Information Resource

Short communication: the cardiac myosin binding protein C Arg502Trp mutation: a common cause of hypertrophic cardiomyopathy.
PubMed Identifier: 20378854
author list: Saltzman AJ, Mancini-DiNardo D, Li C, Chung WK, Ho CY, Hurst S, Wynn J, Care M, Hamilton RM, Seidman GW, Gorham J, McDonough B, Sparks E, Seidman JG, Seidman CE, Rehm HL
published in: Circulation research
information resource reference: Short communication: the cardiac myosin binding protein C Arg502Trp mutation: a common cause of hypertrophic cardiomyopathy. Circ Res. 2010 May 14; 106(9):1549-52.
journal title abbreviation: Circ Res
publication date: 2010-04-08T00:00:00
year: 2010
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1067514
type: Authorship
author rank in publication: 8
linked author: Seidman, Christine
linked information resource: Dynamic Cellular Integration Drives Functional Assembly of the Heart's Pacemaker Complex.

Authorship 1068337
type: Authorship
author rank in publication: 8
linked author: Seidman, Christine
linked information resource: CRISPR/Cas9-Mediated Fluorescent Tagging of Endogenous Proteins in Human Pluripotent Stem Cells.

Dynamic Cellular Integration Drives Functional Assembly of the Heart's Pacemaker Complex.
PubMed Identifier: 29791840
author list: Bressan M, Henley T, Louie JD, Liu G, Christodoulou D, Bai X, Taylor J, Seidman CE, Seidman JG, Mikawa T
published in: Cell reports
information resource reference: Dynamic Cellular Integration Drives Functional Assembly of the Heart's Pacemaker Complex. Cell Rep. 2018 05 22; 23(8):2283-2291.
journal title abbreviation: Cell Rep
publication date: 2018-05-22T00:00:00
year: 2018
type: Academic Article
type: Article
type: Document
type: Information Resource

Identifying sarcomere gene mutations in hypertrophic cardiomyopathy: a personal history.
PubMed Identifier: 21415408
author list: Seidman CE, Seidman JG
published in: Circulation research
information resource reference: Identifying sarcomere gene mutations in hypertrophic cardiomyopathy: a personal history. Circ Res. 2011 Mar 18; 108(6):743-50.
journal title abbreviation: Circ Res
publication date: 2011-03-18T00:00:00
year: 2011
type: Academic Article
type: Article
type: Document
type: Information Resource

Human Induced Pluripotent Stem Cell Production and Expansion from Blood using a Non-Integrating Viral Reprogramming Vector.
PubMed Identifier: 29851250
author list: Sharma A, Mücke M, Seidman CE
published in: Current protocols in molecular biology
information resource reference: Human Induced Pluripotent Stem Cell Production and Expansion from Blood using a Non-Integrating Viral Reprogramming Vector. Curr Protoc Mol Biol. 2018 04; 122(1):e58.
journal title abbreviation: Curr Protoc Mol Biol
publication date: 2018-04-01T00:00:00
year: 2018
type: Academic Article
type: Article
type: Document
type: Information Resource

https://connects.catalyst.harvard.edu/Profiles/profile/1043563
PubMed Identifier: 22075469
author list: Gersh BJ, Maron BJ, Bonow RO, Dearani JA, Fifer MA, Link MS, Naidu SS, Nishimura RA, Ommen SR, Rakowski H, Seidman CE, Towbin JA, Udelson JE, Yancy CW
published in: Journal of the American College of Cardiology
information resource reference: 2011 ACCF/AHA Guideline for the Diagnosis and Treatment of Hypertrophic Cardiomyopathy: a report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines. Developed in collaboration with the American Association for Thoracic Surgery, American Society of Echocardiography, American Society of Nuclear Cardiology, Heart Failure Society of America, Heart Rhythm Society, Society for Cardiovascular Angiography and Interventions, and Society of Thoracic Surgeons. J Am Coll Cardiol. 2011 Dec 13; 58(25):e212-60.
journal title abbreviation: J Am Coll Cardiol
publication date: 2011-11-08T00:00:00
year: 2011
type: Academic Article
type: Article
type: Document
type: Information Resource
label: 2011 ACCF/AHA Guideline for the Diagnosis and Treatment of Hypertrophic Cardiomyopathy: a report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines. Developed in collaboration with the American Association for Thoracic Surgery, American Society of Echocardiography, American Society of Nuclear Cardiology, Heart Failure Society of America, Heart Rhythm Society, Society for Cardiovascular Angiography and Interventions, and Society of Thoracic Surgeons.

Molecular epidemiology of hypertrophic cardiomyopathy.
PubMed Identifier: 12858563
author list: Morita H, DePalma SR, Arad M, McDonough B, Barr S, Duffy C, Maron BJ, Seidman CE, Seidman JG
published in: Cold Spring Harbor symposia on quantitative biology
information resource reference: Molecular epidemiology of hypertrophic cardiomyopathy. Cold Spring Harb Symp Quant Biol. 2002; 67:383-8.
journal title abbreviation: Cold Spring Harb Symp Quant Biol
publication date: 2002-01-01T00:00:00
year: 2002
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1069429
type: Authorship
author rank in publication: 3
linked author: Seidman, Christine
linked information resource: Human Induced Pluripotent Stem Cell Production and Expansion from Blood using a Non-Integrating Viral Reprogramming Vector.

Authorship 108378
type: Authorship
author rank in publication: 15
linked author: Seidman, Christine
linked information resource: Lamin A/C haploinsufficiency causes dilated cardiomyopathy and apoptosis-triggered cardiac conduction system disease.

Familial hypertrophic cardiomyopathy is a genetically heterogeneous disease.
PubMed Identifier: 1975599
author list: Solomon SD, Jarcho JA, McKenna W, Geisterfer-Lowrance A, Germain R, Salerni R, Seidman JG, Seidman CE
published in: The Journal of clinical investigation
information resource reference: Familial hypertrophic cardiomyopathy is a genetically heterogeneous disease. J Clin Invest. 1990 Sep; 86(3):993-9.
journal title abbreviation: J Clin Invest
publication date: 1990-09-01T00:00:00
year: 1990
type: Academic Article
type: Article
type: Document
type: Information Resource

Increased alpha2 subunit-associated AMPK activity and PRKAG2 cardiomyopathy.
PubMed Identifier: 16275868
author list: Ahmad F, Arad M, Musi N, He H, Wolf C, Branco D, Perez-Atayde AR, Stapleton D, Bali D, Xing Y, Tian R, Goodyear LJ, Berul CI, Ingwall JS, Seidman CE, Seidman JG
published in: Circulation
information resource reference: Increased alpha2 subunit-associated AMPK activity and PRKAG2 cardiomyopathy. Circulation. 2005 Nov 15; 112(20):3140-8.
journal title abbreviation: Circulation
publication date: 2005-11-07T00:00:00
year: 2005
type: Academic Article
type: Article
type: Document
type: Information Resource

Molecular medicine in the 21st century.
PubMed Identifier: 11478359
author list: Semsarian C, Seidman CE
published in: Internal medicine journal
information resource reference: Molecular medicine in the 21st century. Intern Med J. 2001 Jan-Feb; 31(1):53-9.
journal title abbreviation: Intern Med J
publication date: 2001-01-01T00:00:00
year: 2001
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1074349
type: Authorship
author rank in publication: 21
linked author: Seidman, Christine
linked information resource: A gene-centric strategy for identifying disease-causing rare variants in dilated cardiomyopathy.

A gene-centric strategy for identifying disease-causing rare variants in dilated cardiomyopathy.
PubMed Identifier: 29892087
author list: Horvat C, Johnson R, Lam L, Munro J, Mazzarotto F, Roberts AM, Herman DS, Parfenov M, Haghighi A, McDonough B, DePalma SR, Keogh AM, Macdonald PS, Hayward CS, Roberts A, Barton PJR, Felkin LE, Giannoulatou E, Cook SA, Seidman JG, Seidman CE, Fatkin D
published in: Genetics in medicine : official journal of the American College of Medical Genetics
information resource reference: A gene-centric strategy for identifying disease-causing rare variants in dilated cardiomyopathy. Genet Med. 2019 01; 21(1):133-143.
journal title abbreviation: Genet Med
publication date: 2018-06-11T00:00:00
year: 2018
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 109153
type: Authorship
author rank in publication: 7
linked author: Seidman, Christine
linked information resource: Neonatal cardiomyopathy in mice homozygous for the Arg403Gln mutation in the alpha cardiac myosin heavy chain gene.

Authorship 1077516
type: Authorship
author rank in publication: 14
linked author: Seidman, Christine
linked information resource: Genome sequencing as a first-line genetic test in familial dilated cardiomyopathy.

Genome sequencing as a first-line genetic test in familial dilated cardiomyopathy.
PubMed Identifier: 29961767
author list: Minoche AE, Horvat C, Johnson R, Gayevskiy V, Morton SU, Drew AP, Woo K, Statham AL, Lundie B, Bagnall RD, Ingles J, Semsarian C, Seidman JG, Seidman CE, Dinger ME, Cowley MJ, Fatkin D
published in: Genetics in medicine : official journal of the American College of Medical Genetics
information resource reference: Genome sequencing as a first-line genetic test in familial dilated cardiomyopathy. Genet Med. 2019 03; 21(3):650-662.
journal title abbreviation: Genet Med
publication date: 2018-07-02T00:00:00
year: 2018
type: Academic Article
type: Article
type: Document
type: Information Resource

Gene mutations in apical hypertrophic cardiomyopathy.
PubMed Identifier: 16267253
author list: Arad M, Penas-Lado M, Monserrat L, Maron BJ, Sherrid M, Ho CY, Barr S, Karim A, Olson TM, Kamisago M, Seidman JG, Seidman CE
published in: Circulation
information resource reference: Gene mutations in apical hypertrophic cardiomyopathy. Circulation. 2005 Nov 01; 112(18):2805-11.
journal title abbreviation: Circulation
publication date: 2005-11-01T00:00:00
year: 2005
type: Academic Article
type: Article
type: Document
type: Information Resource

Missense mutations in the BCS1L gene as a cause of the Björnstad syndrome.
PubMed Identifier: 17314340
author list: Hinson JT, Fantin VR, Schönberger J, Breivik N, Siem G, McDonough B, Sharma P, Keogh I, Godinho R, Santos F, Esparza A, Nicolau Y, Selvaag E, Cohen BH, Hoppel CL, Tranebjaerg L, Eavey RD, Seidman JG, Seidman CE
published in: The New England journal of medicine
information resource reference: Missense mutations in the BCS1L gene as a cause of the Björnstad syndrome. N Engl J Med. 2007 Feb 22; 356(8):809-19.
journal title abbreviation: N Engl J Med
publication date: 2007-02-22T00:00:00
year: 2007
type: Academic Article
type: Article
type: Document
type: Information Resource

Genomewide linkage in a large Caucasian family maps a new locus for intracranial aneurysms to chromosome 13q.
PubMed Identifier: 19064780
author list: Santiago-Sim T, Depalma SR, Ju KL, McDonough B, Seidman CE, Seidman JG, Kim DH
published in: Stroke
information resource reference: Genomewide linkage in a large Caucasian family maps a new locus for intracranial aneurysms to chromosome 13q. Stroke. 2009 Mar; 40(3 Suppl):S57-60.
journal title abbreviation: Stroke
publication date: 2008-12-08T00:00:00
year: 2008
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1079504
type: Authorship
author rank in publication: 6
linked author: Seidman, Christine
linked information resource: Molecular Genetics of Lidocaine-Containing Cardioplegia in the Human Heart During Cardiac Surgery.

Molecular Genetics of Lidocaine-Containing Cardioplegia in the Human Heart During Cardiac Surgery.
PubMed Identifier: 30028983
author list: Heydarpour M, Ejiofor J, Gilfeather M, Stone G, Gorham J, Seidman CE, Seidman JG, Yammine M, Body SC, Aranki SF, Muehlschlegel JD
published in: The Annals of thoracic surgery
information resource reference: Molecular Genetics of Lidocaine-Containing Cardioplegia in the Human Heart During Cardiac Surgery. Ann Thorac Surg. 2018 11; 106(5):1379-1387.
journal title abbreviation: Ann Thorac Surg
publication date: 2018-07-17T00:00:00
year: 2018
type: Academic Article
type: Article
type: Document
type: Information Resource

A molecular pathway including Id2, Tbx5, and Nkx2-5 required for cardiac conduction system development.
PubMed Identifier: 17604724
author list: Moskowitz IP, Kim JB, Moore ML, Wolf CM, Peterson MA, Shendure J, Nobrega MA, Yokota Y, Berul C, Izumo S, Seidman JG, Seidman CE
published in: Cell
information resource reference: A molecular pathway including Id2, Tbx5, and Nkx2-5 required for cardiac conduction system development. Cell. 2007 Jun 29; 129(7):1365-76.
journal title abbreviation: Cell
publication date: 2007-06-29T00:00:00
year: 2007
type: Academic Article
type: Article
type: Document
type: Information Resource

Shared genetic causes of cardiac hypertrophy in children and adults.
PubMed Identifier: 18403758
author list: Morita H, Rehm HL, Menesses A, McDonough B, Roberts AE, Kucherlapati R, Towbin JA, Seidman JG, Seidman CE
published in: The New England journal of medicine
information resource reference: Shared genetic causes of cardiac hypertrophy in children and adults. N Engl J Med. 2008 May 01; 358(18):1899-908.
journal title abbreviation: N Engl J Med
publication date: 2008-04-09T00:00:00
year: 2008
type: Academic Article
type: Article
type: Document
type: Information Resource

Functional effects of the TMEM43 Ser358Leu mutation in the pathogenesis of arrhythmogenic right ventricular cardiomyopathy.
PubMed Identifier: 22458570
author list: Rajkumar R, Sembrat JC, McDonough B, Seidman CE, Ahmad F
published in: BMC medical genetics
information resource reference: Functional effects of the TMEM43 Ser358Leu mutation in the pathogenesis of arrhythmogenic right ventricular cardiomyopathy. BMC Med Genet. 2012 Mar 29; 13:21.
journal title abbreviation: BMC Med Genet
publication date: 2012-03-29T00:00:00
year: 2012
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1083621
type: Authorship
author rank in publication: 4
linked author: Seidman, Christine
linked information resource: In vivo and In vitro methods to identify DNA sequence variants that alter RNA Splicing.

In vivo and In vitro methods to identify DNA sequence variants that alter RNA Splicing.
PubMed Identifier: 30038698
author list: Patel PN, Gorham JM, Ito K, Seidman CE
published in: Current protocols in human genetics
information resource reference: In vivo and In vitro methods to identify DNA sequence variants that alter RNA Splicing. Curr Protoc Hum Genet. 2018 04; 97(1):e60.
journal title abbreviation: Curr Protoc Hum Genet
publication date: 2018-04-26T00:00:00
year: 2018
type: Academic Article
type: Article
type: Document
type: Information Resource

A public resource facilitating clinical use of genomes.
PubMed Identifier: 22797899
author list: Ball MP, Thakuria JV, Zaranek AW, Clegg T, Rosenbaum AM, Wu X, Angrist M, Bhak J, Bobe J, Callow MJ, Cano C, Chou MF, Chung WK, Douglas SM, Estep PW, Gore A, Hulick P, Labarga A, Lee JH, Lunshof JE, Kim BC, Kim JI, Li Z, Murray MF, Nilsen GB, Peters BA, Raman AM, Rienhoff HY, Robasky K, Wheeler MT, Vandewege W, Vorhaus DB, Yang JL, Yang L, Aach J, Ashley EA, Drmanac R, Kim SJ, Li JB, Peshkin L, Seidman CE, Seo JS, Zhang K, Rehm HL, Church GM
published in: Proceedings of the National Academy of Sciences of the United States of America
information resource reference: A public resource facilitating clinical use of genomes. Proc Natl Acad Sci U S A. 2012 Jul 24; 109(30):11920-7.
journal title abbreviation: Proc Natl Acad Sci U S A
publication date: 2012-07-13T00:00:00
year: 2012
type: Academic Article
type: Article
type: Document
type: Information Resource

Spectrum of somatic mitochondrial mutations in five cancers.
PubMed Identifier: 22891333
author list: Larman TC, DePalma SR, Hadjipanayis AG, Protopopov A, Zhang J, Gabriel SB, Chin L, Seidman CE, Kucherlapati R, Seidman JG
published in: Proceedings of the National Academy of Sciences of the United States of America
information resource reference: Spectrum of somatic mitochondrial mutations in five cancers. Proc Natl Acad Sci U S A. 2012 Aug 28; 109(35):14087-91.
journal title abbreviation: Proc Natl Acad Sci U S A
publication date: 2012-08-13T00:00:00
year: 2012
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1085474
type: Authorship
author rank in publication: 8
linked author: Seidman, Christine
linked information resource: The Transcriptional Signature of Growth in Human Fetal Aortic Valve Development.

The Transcriptional Signature of Growth in Human Fetal Aortic Valve Development.
PubMed Identifier: 30071238
author list: Gottlieb Sen D, Halu A, Razzaque A, Gorham JM, Hartnett J, Seidman JG, Aikawa E, Seidman CE
published in: The Annals of thoracic surgery
information resource reference: The Transcriptional Signature of Growth in Human Fetal Aortic Valve Development. Ann Thorac Surg. 2018 12; 106(6):1834-1840.
journal title abbreviation: Ann Thorac Surg
publication date: 2018-07-30T00:00:00
year: 2018
type: Academic Article
type: Article
type: Document
type: Information Resource

A dinucleotide repeat polymorphism in the MYBPH gene.
PubMed Identifier: 7881442
author list: Watkins H, MacRae CA, Fischman DA, Seidman JG, Seidman CE
published in: Human molecular genetics
information resource reference: A dinucleotide repeat polymorphism in the MYBPH gene. Hum Mol Genet. 1994 Dec; 3(12):2267.
journal title abbreviation: Hum Mol Genet
publication date: 1994-12-01T00:00:00
year: 1994
type: Academic Article
type: Article
type: Document
type: Information Resource

An integrated clinical program and crowdsourcing strategy for genomic sequencing and Mendelian disease gene discovery.
PubMed Identifier: 30131872
author list: Haghighi A, Krier JB, Toth-Petroczy A, Cassa CA, Frank NY, Carmichael N, Fieg E, Bjonnes A, Mohanty A, Briere LC, Lincoln S, Lucia S, Gupta VA, Söylemez O, Sutti S, Kooshesh K, Qiu H, Fay CJ, Perroni V, Valerius J, Hanna M, Frank A, Ouahed J, Snapper SB, Pantazi A, Chopra SS, Leshchiner I, Stitziel NO, Feldweg A, Mannstadt M, Loscalzo J, Sweetser DA, Liao E, Stoler JM, Nowak CB, Sanchez-Lara PA, Klein OD, Perry H, Patsopoulos NA, Raychaudhuri S, Goessling W, Green RC, Seidman CE, MacRae CA, Sunyaev SR, Maas RL, Vuzman D
published in: NPJ genomic medicine
information resource reference: An integrated clinical program and crowdsourcing strategy for genomic sequencing and Mendelian disease gene discovery. NPJ Genom Med. 2018; 3:21.
journal title abbreviation: NPJ Genom Med
publication date: 2018-08-13T00:00:00
year: 2018
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1089735
type: Authorship
author rank in publication: 27
linked author: Seidman, Christine
linked information resource: Association of Variants in BAG3 With Cardiomyopathy Outcomes in African American Individuals.

Authorship 1089525
type: Authorship
author rank in publication: 43
linked author: Seidman, Christine
linked information resource: An integrated clinical program and crowdsourcing strategy for genomic sequencing and Mendelian disease gene discovery.

Association of Variants in BAG3 With Cardiomyopathy Outcomes in African American Individuals.
PubMed Identifier: 30140897
author list: Myers VD, Gerhard GS, McNamara DM, Tomar D, Madesh M, Kaniper S, Ramsey FV, Fisher SG, Ingersoll RG, Kasch-Semenza L, Wang J, Hanley-Yanez K, Lemster B, Schwisow JA, Ambardekar AV, Degann SH, Bristow MR, Sheppard R, Alexis JD, Tilley DG, Kontos CD, McClung JM, Taylor AL, Yancy CW, Khalili K, Seidman JG, Seidman CE, McTiernan CF, Cheung JY, Feldman AM
published in: JAMA cardiology
information resource reference: Association of Variants in BAG3 With Cardiomyopathy Outcomes in African American Individuals. JAMA Cardiol. 2018 10 01; 3(10):929-938.
journal title abbreviation: JAMA Cardiol
publication date: 2018-10-01T00:00:00
year: 2018
type: Academic Article
type: Article
type: Document
type: Information Resource

Pheochromocytoma-induced cardiomyopathy is modulated by the synergistic effects of cell-secreted factors.
PubMed Identifier: 19808327
author list: Mobine HR, Baker AB, Wang L, Wakimoto H, Jacobsen KC, Seidman CE, Seidman JG, Edelman ER
published in: Circulation. Heart failure
information resource reference: Pheochromocytoma-induced cardiomyopathy is modulated by the synergistic effects of cell-secreted factors. Circ Heart Fail. 2009 Mar; 2(2):121-8.
journal title abbreviation: Circ Heart Fail
publication date: 2009-02-10T00:00:00
year: 2009
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1090627
type: Authorship
author rank in publication: 9
linked author: Seidman, Christine
linked information resource: The Role of the L-Type Ca2+ Channel in Altered Metabolic Activity in a Murine Model of Hypertrophic Cardiomyopathy.

Authorship 1090856
type: Authorship
author rank in publication: 14
linked author: Seidman, Christine
linked information resource: Telomere shortening is a hallmark of genetic cardiomyopathies.

Telomere shortening is a hallmark of genetic cardiomyopathies.
PubMed Identifier: 30150400
author list: Chang ACY, Chang ACH, Kirillova A, Sasagawa K, Su W, Weber G, Lin J, Termglinchan V, Karakikes I, Seeger T, Dainis AM, Hinson JT, Seidman J, Seidman CE, Day JW, Ashley E, Wu JC, Blau HM
published in: Proceedings of the National Academy of Sciences of the United States of America
information resource reference: Telomere shortening is a hallmark of genetic cardiomyopathies. Proc Natl Acad Sci U S A. 2018 09 11; 115(37):9276-9281.
journal title abbreviation: Proc Natl Acad Sci U S A
publication date: 2018-08-27T00:00:00
year: 2018
type: Academic Article
type: Article
type: Document
type: Information Resource

The Role of the L-Type Ca2+ Channel in Altered Metabolic Activity in a Murine Model of Hypertrophic Cardiomyopathy.
PubMed Identifier: 30167506
author list: Viola HM, Johnstone VPA, Cserne Szappanos H, Richman TR, Tsoutsman T, Filipovska A, Semsarian C, Seidman JG, Seidman CE, Hool LC
published in: JACC. Basic to translational science
information resource reference: The Role of the L-Type Ca2+ Channel in Altered Metabolic Activity in a Murine Model of Hypertrophic Cardiomyopathy. JACC Basic Transl Sci. 2016 Jan-Feb; 1(1-2):61-72.
journal title abbreviation: JACC Basic Transl Sci
publication date: 2016-02-13T00:00:00
year: 2016
type: Academic Article
type: Article
type: Document
type: Information Resource

Altered hepatic transport of immunoglobulin A in mice lacking the J chain.
PubMed Identifier: 7500036
author list: Hendrickson BA, Conner DA, Ladd DJ, Kendall D, Casanova JE, Corthesy B, Max EE, Neutra MR, Seidman CE, Seidman JG
published in: The Journal of experimental medicine
information resource reference: Altered hepatic transport of immunoglobulin A in mice lacking the J chain. J Exp Med. 1995 Dec 01; 182(6):1905-11.
journal title abbreviation: J Exp Med
publication date: 1995-12-01T00:00:00
year: 1995
type: Academic Article
type: Article
type: Document
type: Information Resource

A dominant Stargardt's macular dystrophy locus maps to chromosome 13q34.
PubMed Identifier: 8002833
author list: Zhang K, Bither PP, Park R, Donoso LA, Seidman JG, Seidman CE
published in: Archives of ophthalmology (Chicago, Ill. : 1960)
information resource reference: A dominant Stargardt's macular dystrophy locus maps to chromosome 13q34. Arch Ophthalmol. 1994 Jun; 112(6):759-64.
journal title abbreviation: Arch Ophthalmol
publication date: 1994-06-01T00:00:00
year: 1994
type: Academic Article
type: Article
type: Document
type: Information Resource

An evaluation of ribonuclease protection assays for the detection of beta-cardiac myosin heavy chain gene mutations.
PubMed Identifier: 8281665
author list: MacRae CA, Watkins HC, Jarcho JA, Thierfelder L, McKenna WJ, Seidman JG, Seidman CE
published in: Circulation
information resource reference: An evaluation of ribonuclease protection assays for the detection of beta-cardiac myosin heavy chain gene mutations. Circulation. 1994 Jan; 89(1):33-5.
journal title abbreviation: Circulation
publication date: 1994-01-01T00:00:00
year: 1994
type: Academic Article
type: Article
type: Document
type: Information Resource

Genome-wide association study identifies a susceptibility locus for thoracic aortic aneurysms and aortic dissections spanning FBN1 at 15q21.1.
PubMed Identifier: 21909107
author list: LeMaire SA, McDonald ML, Guo DC, Russell L, Miller CC, Johnson RJ, Bekheirnia MR, Franco LM, Nguyen M, Pyeritz RE, Bavaria JE, Devereux R, Maslen C, Holmes KW, Eagle K, Body SC, Seidman C, Seidman JG, Isselbacher EM, Bray M, Coselli JS, Estrera AL, Safi HJ, Belmont JW, Leal SM, Milewicz DM
published in: Nature genetics
information resource reference: Genome-wide association study identifies a susceptibility locus for thoracic aortic aneurysms and aortic dissections spanning FBN1 at 15q21.1. Nat Genet. 2011 Sep 11; 43(10):996-1000.
journal title abbreviation: Nat Genet
publication date: 2011-09-11T00:00:00
year: 2011
type: Academic Article
type: Article
type: Document
type: Information Resource

Epigenetic repression of cardiac progenitor gene expression by Ezh2 is required for postnatal cardiac homeostasis.
PubMed Identifier: 22267199
author list: Delgado-Olguín P, Huang Y, Li X, Christodoulou D, Seidman CE, Seidman JG, Tarakhovsky A, Bruneau BG
published in: Nature genetics
information resource reference: Epigenetic repression of cardiac progenitor gene expression by Ezh2 is required for postnatal cardiac homeostasis. Nat Genet. 2012 Jan 22; 44(3):343-7.
journal title abbreviation: Nat Genet
publication date: 2012-01-22T00:00:00
year: 2012
type: Academic Article
type: Article
type: Document
type: Information Resource

Subtle abnormalities in contractile function are an early manifestation of sarcomere mutations in dilated cardiomyopathy.
PubMed Identifier: 22949430
author list: Lakdawala NK, Thune JJ, Colan SD, Cirino AL, Farrohi F, Rivero J, McDonough B, Sparks E, Orav EJ, Seidman JG, Seidman CE, Ho CY
published in: Circulation. Cardiovascular genetics
information resource reference: Subtle abnormalities in contractile function are an early manifestation of sarcomere mutations in dilated cardiomyopathy. Circ Cardiovasc Genet. 2012 Oct 01; 5(5):503-10.
journal title abbreviation: Circ Cardiovasc Genet
publication date: 2012-09-04T00:00:00
year: 2012
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1093015
type: Authorship
author rank in publication: 17
linked author: Seidman, Christine
linked information resource: Hierarchical and stage-specific regulation of murine cardiomyocyte maturation by serum response factor.

Hierarchical and stage-specific regulation of murine cardiomyocyte maturation by serum response factor.
PubMed Identifier: 30242271
author list: Guo Y, Jardin BD, Zhou P, Sethi I, Akerberg BN, Toepfer CN, Ai Y, Li Y, Ma Q, Guatimosim S, Hu Y, Varuzhanyan G, VanDusen NJ, Zhang D, Chan DC, Yuan GC, Seidman CE, Seidman JG, Pu WT
published in: Nature communications
information resource reference: Hierarchical and stage-specific regulation of murine cardiomyocyte maturation by serum response factor. Nat Commun. 2018 09 21; 9(1):3837.
journal title abbreviation: Nat Commun
publication date: 2018-09-21T00:00:00
year: 2018
type: Academic Article
type: Article
type: Document
type: Information Resource

Age-related autocrine diabetogenic effects of transgenic resistin in spontaneously hypertensive rats: gene expression profile analysis.
PubMed Identifier: 21285283
author list: Pravenec M, Zídek V, Landa V, Simáková M, Mlejnek P, Silhavy J, Maxová M, Kazdová L, Seidman JG, Seidman CE, Eminaga S, Gorham J, Wang J, Kurtz TW
published in: Physiological genomics
information resource reference: Age-related autocrine diabetogenic effects of transgenic resistin in spontaneously hypertensive rats: gene expression profile analysis. Physiol Genomics. 2011 Apr 12; 43(7):372-9.
journal title abbreviation: Physiol Genomics
publication date: 2011-02-01T00:00:00
year: 2011
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 118852
type: Authorship
author rank in publication: 14
linked author: Seidman, Christine
linked information resource: Mutations in human TBX3 alter limb, apocrine and genital development in ulnar-mammary syndrome.

https://connects.catalyst.harvard.edu/Profiles/profile/1105934
PubMed Identifier: 22093723
author list: Gersh BJ, Maron BJ, Bonow RO, Dearani JA, Fifer MA, Link MS, Naidu SS, Nishimura RA, Ommen SR, Rakowski H, Seidman CE, Towbin JA, Udelson JE, Yancy CW
published in: The Journal of thoracic and cardiovascular surgery
information resource reference: 2011 ACCF/AHA guideline for the diagnosis and treatment of hypertrophic cardiomyopathy: a report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines. J Thorac Cardiovasc Surg. 2011 Dec; 142(6):e153-203.
journal title abbreviation: J Thorac Cardiovasc Surg
publication date: 2011-12-01T00:00:00
year: 2011
type: Academic Article
type: Article
type: Document
type: Information Resource
label: 2011 ACCF/AHA guideline for the diagnosis and treatment of hypertrophic cardiomyopathy: a report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines.

Hypertrophic cardiomyopathy: translating cellular cross talk into therapeutics.
PubMed Identifier: 23109667
author list: Teekakirikul P, Padera RF, Seidman JG, Seidman CE
published in: The Journal of cell biology
information resource reference: Hypertrophic cardiomyopathy: translating cellular cross talk into therapeutics. J Cell Biol. 2012 Oct 29; 199(3):417-21.
journal title abbreviation: J Cell Biol
publication date: 2012-10-29T00:00:00
year: 2012
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1096124
type: Authorship
author rank in publication: 14
linked author: Seidman, Christine
linked information resource: Response to Brodehl et al.

Authorship 1096828
type: Authorship
author rank in publication: 6
linked author: Seidman, Christine
linked information resource: Multilayer Myocardial Mechanics in Genotype-Positive Left Ventricular Hypertrophy-Negative Patients With Hypertrophic Cardiomyopathy.

Multilayer Myocardial Mechanics in Genotype-Positive Left Ventricular Hypertrophy-Negative Patients With Hypertrophic Cardiomyopathy.
PubMed Identifier: 30249441
author list: Williams LK, Misurka J, Ho CY, Chan WX, Agmon Y, Seidman C, Rakowski H, Carasso S
published in: The American journal of cardiology
information resource reference: Multilayer Myocardial Mechanics in Genotype-Positive Left Ventricular Hypertrophy-Negative Patients With Hypertrophic Cardiomyopathy. Am J Cardiol. 2018 11 15; 122(10):1754-1760.
journal title abbreviation: Am J Cardiol
publication date: 2018-08-21T00:00:00
year: 2018
type: Academic Article
type: Article
type: Document
type: Information Resource

Response to Brodehl et al.
PubMed Identifier: 30262924
author list: Minoche AE, Horvat C, Johnson R, Gayevskiy V, Morton SU, Drew AP, Woo K, Statham AL, Lundie B, Bagnall RD, Ingles J, Semsarian C, Seidman JG, Seidman CE, Dinger ME, Cowley MJ, Fatkin D
published in: Genetics in medicine : official journal of the American College of Medical Genetics
information resource reference: Response to Brodehl et al. Genet Med. 2019 05; 21(5):1248-1249.
journal title abbreviation: Genet Med
publication date: 2018-09-28T00:00:00
year: 2018
type: Academic Article
type: Article
type: Document
type: Information Resource

Genetic causes of human heart failure.
PubMed Identifier: 15765133
author list: Morita H, Seidman J, Seidman CE
published in: The Journal of clinical investigation
information resource reference: Genetic causes of human heart failure. J Clin Invest. 2005 Mar; 115(3):518-26.
journal title abbreviation: J Clin Invest
publication date: 2005-03-01T00:00:00
year: 2005
type: Academic Article
type: Article
type: Document
type: Information Resource

Compound and double mutations in patients with hypertrophic cardiomyopathy: implications for genetic testing and counselling.
PubMed Identifier: 16199542
author list: Ingles J, Doolan A, Chiu C, Seidman J, Seidman C, Semsarian C
published in: Journal of medical genetics
information resource reference: Compound and double mutations in patients with hypertrophic cardiomyopathy: implications for genetic testing and counselling. J Med Genet. 2005 Oct; 42(10):e59.
journal title abbreviation: J Med Genet
publication date: 2005-10-01T00:00:00
year: 2005
type: Academic Article
type: Article
type: Document
type: Information Resource

Cardiac myosin-binding protein-C phosphorylation and cardiac function.
PubMed Identifier: 16224063
author list: Sadayappan S, Gulick J, Osinska H, Martin LA, Hahn HS, Dorn GW, Klevitsky R, Seidman CE, Seidman JG, Robbins J
published in: Circulation research
information resource reference: Cardiac myosin-binding protein-C phosphorylation and cardiac function. Circ Res. 2005 Nov 25; 97(11):1156-63.
journal title abbreviation: Circ Res
publication date: 2005-10-13T00:00:00
year: 2005
type: Academic Article
type: Article
type: Document
type: Information Resource

Polony multiplex analysis of gene expression (PMAGE) in mouse hypertrophic cardiomyopathy.
PubMed Identifier: 17556586
author list: Kim JB, Porreca GJ, Song L, Greenway SC, Gorham JM, Church GM, Seidman CE, Seidman JG
published in: Science (New York, N.Y.)
information resource reference: Polony multiplex analysis of gene expression (PMAGE) in mouse hypertrophic cardiomyopathy. Science. 2007 Jun 08; 316(5830):1481-4.
journal title abbreviation: Science
publication date: 2007-06-08T00:00:00
year: 2007
type: Academic Article
type: Article
type: Document
type: Information Resource

Mutations in the human Ca(2+)-sensing receptor gene cause familial hypocalciuric hypercalcemia and neonatal severe hyperparathyroidism.
PubMed Identifier: 7916660
author list: Pollak MR, Brown EM, Chou YH, Hebert SC, Marx SJ, Steinmann B, Levi T, Seidman CE, Seidman JG
published in: Cell
information resource reference: Mutations in the human Ca(2+)-sensing receptor gene cause familial hypocalciuric hypercalcemia and neonatal severe hyperparathyroidism. Cell. 1993 Dec 31; 75(7):1297-303.
journal title abbreviation: Cell
publication date: 1993-12-31T00:00:00
year: 1993
type: Academic Article
type: Article
type: Document
type: Information Resource

Alpha-tropomyosin and cardiac troponin T mutations cause familial hypertrophic cardiomyopathy: a disease of the sarcomere.
PubMed Identifier: 8205619
author list: Thierfelder L, Watkins H, MacRae C, Lamas R, McKenna W, Vosberg HP, Seidman JG, Seidman CE
published in: Cell
information resource reference: Alpha-tropomyosin and cardiac troponin T mutations cause familial hypertrophic cardiomyopathy: a disease of the sarcomere. Cell. 1994 Jun 03; 77(5):701-12.
journal title abbreviation: Cell
publication date: 1994-06-03T00:00:00
year: 1994
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 107008
type: Authorship
author rank in publication: 2
linked author: Seidman, Christine
linked information resource: How should hypertrophic cardiomyopathy be classified?: What's in a name? Dilemmas in nomenclature characterizing hypertrophic cardiomyopathy and left ventricular hypertrophy.

Authorship 1099120
type: Authorship
author rank in publication: 16
linked author: Seidman, Christine
linked information resource: Genotype and Lifetime Burden of Disease in Hypertrophic Cardiomyopathy: Insights from the Sarcomeric Human Cardiomyopathy Registry (SHaRe).

Genotype and Lifetime Burden of Disease in Hypertrophic Cardiomyopathy: Insights from the Sarcomeric Human Cardiomyopathy Registry (SHaRe).
PubMed Identifier: 30297972
author list: Ho CY, Day SM, Ashley EA, Michels M, Pereira AC, Jacoby D, Cirino AL, Fox JC, Lakdawala NK, Ware JS, Caleshu CA, Helms AS, Colan SD, Girolami F, Cecchi F, Seidman CE, Sajeev G, Signorovitch J, Green EM, Olivotto I
published in: Circulation
information resource reference: Genotype and Lifetime Burden of Disease in Hypertrophic Cardiomyopathy: Insights from the Sarcomeric Human Cardiomyopathy Registry (SHaRe). Circulation. 2018 10 02; 138(14):1387-1398.
journal title abbreviation: Circulation
publication date: 2018-08-23T00:00:00
year: 2018
type: Academic Article
type: Article
type: Document
type: Information Resource

Mutations in human TBX3 alter limb, apocrine and genital development in ulnar-mammary syndrome.
PubMed Identifier: 9207801
author list: Bamshad M, Lin RC, Law DJ, Watkins WC, Krakowiak PA, Moore ME, Franceschini P, Lala R, Holmes LB, Gebuhr TC, Bruneau BG, Schinzel A, Seidman JG, Seidman CE, Jorde LB
published in: Nature genetics
information resource reference: Mutations in human TBX3 alter limb, apocrine and genital development in ulnar-mammary syndrome. Nat Genet. 1997 Jul; 16(3):311-5.
journal title abbreviation: Nat Genet
publication date: 1997-07-01T00:00:00
year: 1997
type: Academic Article
type: Article
type: Document
type: Information Resource

Mutations in the cardiac myosin binding protein-C gene on chromosome 11 cause familial hypertrophic cardiomyopathy.
PubMed Identifier: 7493025
author list: Watkins H, Conner D, Thierfelder L, Jarcho JA, MacRae C, McKenna WJ, Maron BJ, Seidman JG, Seidman CE
published in: Nature genetics
information resource reference: Mutations in the cardiac myosin binding protein-C gene on chromosome 11 cause familial hypertrophic cardiomyopathy. Nat Genet. 1995 Dec; 11(4):434-7.
journal title abbreviation: Nat Genet
publication date: 1995-12-01T00:00:00
year: 1995
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 12397
type: Authorship
author rank in publication: 19
linked author: Seidman, Christine
linked information resource: Genetic and environmental risk factors in congenital heart disease functionally converge in protein networks driving heart development.

A human MSX1 homeodomain missense mutation causes selective tooth agenesis.
PubMed Identifier: 8696335
author list: Vastardis H, Karimbux N, Guthua SW, Seidman JG, Seidman CE
published in: Nature genetics
information resource reference: A human MSX1 homeodomain missense mutation causes selective tooth agenesis. Nat Genet. 1996 Aug; 13(4):417-21.
journal title abbreviation: Nat Genet
publication date: 1996-08-01T00:00:00
year: 1996
type: Academic Article
type: Article
type: Document
type: Information Resource

Loss-of-function mutations in the PRPS1 gene cause a type of nonsyndromic X-linked sensorineural deafness, DFN2.
PubMed Identifier: 20021999
author list: Liu X, Han D, Li J, Han B, Ouyang X, Cheng J, Li X, Jin Z, Wang Y, Bitner-Glindzicz M, Kong X, Xu H, Kantardzhieva A, Eavey RD, Seidman CE, Seidman JG, Du LL, Chen ZY, Dai P, Teng M, Yan D, Yuan H
published in: American journal of human genetics
information resource reference: Loss-of-function mutations in the PRPS1 gene cause a type of nonsyndromic X-linked sensorineural deafness, DFN2. Am J Hum Genet. 2010 Jan; 86(1):65-71.
journal title abbreviation: Am J Hum Genet
publication date: 2010-01-01T00:00:00
year: 2010
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1108030
type: Authorship
author rank in publication: 16
linked author: Seidman, Christine
linked information resource: A-Band Titin Truncation in Zebrafish Causes Dilated Cardiomyopathy and Hemodynamic Stress Intolerance.

A-Band Titin Truncation in Zebrafish Causes Dilated Cardiomyopathy and Hemodynamic Stress Intolerance.
PubMed Identifier: 30354343
author list: Huttner IG, Wang LW, Santiago CF, Horvat C, Johnson R, Cheng D, von Frieling-Salewsky M, Hillcoat K, Bemand TJ, Trivedi G, Braet F, Hesselson D, Alford K, Hayward CS, Seidman JG, Seidman CE, Feneley MP, Linke WA, Fatkin D
published in: Circulation. Genomic and precision medicine
information resource reference: A-Band Titin Truncation in Zebrafish Causes Dilated Cardiomyopathy and Hemodynamic Stress Intolerance. Circ Genom Precis Med. 2018 08; 11(8):e002135.
journal title abbreviation: Circ Genom Precis Med
publication date: 2018-08-01T00:00:00
year: 2018
type: Academic Article
type: Article
type: Document
type: Information Resource

Heterogeneous myocyte enhancer factor-2 (Mef2) activation in myocytes predicts focal scarring in hypertrophic cardiomyopathy.
PubMed Identifier: 20923879
author list: Konno T, Chen D, Wang L, Wakimoto H, Teekakirikul P, Nayor M, Kawana M, Eminaga S, Gorham JM, Pandya K, Smithies O, Naya FJ, Olson EN, Seidman JG, Seidman CE
published in: Proceedings of the National Academy of Sciences of the United States of America
information resource reference: Heterogeneous myocyte enhancer factor-2 (Mef2) activation in myocytes predicts focal scarring in hypertrophic cardiomyopathy. Proc Natl Acad Sci U S A. 2010 Oct 19; 107(42):18097-102.
journal title abbreviation: Proc Natl Acad Sci U S A
publication date: 2010-10-05T00:00:00
year: 2010
type: Academic Article
type: Article
type: Document
type: Information Resource

Neonatal atria and ventricles secrete atrial natriuretic factor via tissue-specific secretory pathways.
PubMed Identifier: 2946416
author list: Bloch KD, Seidman JG, Naftilan JD, Fallon JT, Seidman CE
published in: Cell
information resource reference: Neonatal atria and ventricles secrete atrial natriuretic factor via tissue-specific secretory pathways. Cell. 1986 Dec 05; 47(5):695-702.
journal title abbreviation: Cell
publication date: 1986-12-05T00:00:00
year: 1986
type: Academic Article
type: Article
type: Document
type: Information Resource

The clinical and genetic spectrum of the Holt-Oram syndrome (heart-hand syndrome)
PubMed Identifier: 8114858
author list: Basson CT, Cowley GS, Solomon SD, Weissman B, Poznanski AK, Traill TA, Seidman JG, Seidman CE
published in: The New England journal of medicine
information resource reference: The clinical and genetic spectrum of the Holt-Oram syndrome (heart-hand syndrome) N Engl J Med. 1994 Mar 31; 330(13):885-91.
journal title abbreviation: N Engl J Med
publication date: 1994-03-31T00:00:00
year: 1994
type: Academic Article
type: Article
type: Document
type: Information Resource

Human fatty acid synthesis is stimulated by a eucaloric low fat, high carbohydrate diet.
PubMed Identifier: 8621798
author list: Hudgins LC, Hellerstein M, Seidman C, Neese R, Diakun J, Hirsch J
published in: The Journal of clinical investigation
information resource reference: Human fatty acid synthesis is stimulated by a eucaloric low fat, high carbohydrate diet. J Clin Invest. 1996 May 01; 97(9):2081-91.
journal title abbreviation: J Clin Invest
publication date: 1996-05-01T00:00:00
year: 1996
type: Academic Article
type: Article
type: Document
type: Information Resource

QT dispersion in alpha-myosin heavy-chain familial hypertrophic cardiomyopathy mice.
PubMed Identifier: 10231857
author list: Bevilacqua LM, Maguire CT, Seidman JG, Seidman CE, Berul CI
published in: Pediatric research
information resource reference: QT dispersion in alpha-myosin heavy-chain familial hypertrophic cardiomyopathy mice. Pediatr Res. 1999 May; 45(5 Pt 1):643-7.
journal title abbreviation: Pediatr Res
publication date: 1999-05-01T00:00:00
year: 1999
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 134197
type: Authorship
author rank in publication: 3
linked author: Seidman, Christine
linked information resource: Biochemistry and genetics of Klebsiella pneumoniae mutant strains unable to fix N2.

Independent origin of identical beta cardiac myosin heavy-chain mutations in hypertrophic cardiomyopathy.
PubMed Identifier: 8250038
author list: Watkins H, Thierfelder L, Anan R, Jarcho J, Matsumori A, McKenna W, Seidman JG, Seidman CE
published in: American journal of human genetics
information resource reference: Independent origin of identical beta cardiac myosin heavy-chain mutations in hypertrophic cardiomyopathy. Am J Hum Genet. 1993 Dec; 53(6):1180-5.
journal title abbreviation: Am J Hum Genet
publication date: 1993-12-01T00:00:00
year: 1993
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1112359
type: Authorship
author rank in publication: 2
linked author: Seidman, Christine
linked information resource: Genetic Testing and Counseling for Hypertrophic Cardiomyopathy.

Genetic Testing and Counseling for Hypertrophic Cardiomyopathy.
PubMed Identifier: 30447714
author list: Cirino AL, Seidman CE, Ho CY
published in: Cardiology clinics
information resource reference: Genetic Testing and Counseling for Hypertrophic Cardiomyopathy. Cardiol Clin. 2019 Feb; 37(1):35-43.
journal title abbreviation: Cardiol Clin
publication date: 2018-10-29T00:00:00
year: 2018
type: Academic Article
type: Article
type: Document
type: Information Resource

Cardiovascular genomics.
PubMed Identifier: 16549641
author list: Sabatine MS, Seidman JG, Seidman CE
published in: Circulation
information resource reference: Cardiovascular genomics. Circulation. 2006 Mar 21; 113(11):e450-5.
journal title abbreviation: Circulation
publication date: 2006-03-21T00:00:00
year: 2006
type: Academic Article
type: Article
type: Document
type: Information Resource

The structure of rat preproatrial natriuretic factor as defined by a complementary DNA clone.
PubMed Identifier: 6234658
author list: Seidman CE, Duby AD, Choi E, Graham RM, Haber E, Homcy C, Smith JA, Seidman JG
published in: Science (New York, N.Y.)
information resource reference: The structure of rat preproatrial natriuretic factor as defined by a complementary DNA clone. Science. 1984 Jul 20; 225(4659):324-6.
journal title abbreviation: Science
publication date: 1984-07-20T00:00:00
year: 1984
type: Academic Article
type: Article
type: Document
type: Information Resource

The cloning of extracellular Ca(2+)-sensing receptors from parathyroid and kidney: molecular mechanisms of extracellular Ca(2+)-sensing.
PubMed Identifier: 7602378
author list: Brown EM, Pollak M, Chou YH, Seidman CE, Seidman JG, Hebert SC
published in: The Journal of nutrition
information resource reference: The cloning of extracellular Ca(2+)-sensing receptors from parathyroid and kidney: molecular mechanisms of extracellular Ca(2+)-sensing. J Nutr. 1995 07; 125(7 Suppl):1965S-1970S.
journal title abbreviation: J Nutr
publication date: 1995-07-01T00:00:00
year: 1995
type: Academic Article
type: Article
type: Document
type: Information Resource

A mouse model of human familial hypocalciuric hypercalcemia and neonatal severe hyperparathyroidism.
PubMed Identifier: 7493018
author list: Ho C, Conner DA, Pollak MR, Ladd DJ, Kifor O, Warren HB, Brown EM, Seidman JG, Seidman CE
published in: Nature genetics
information resource reference: A mouse model of human familial hypocalciuric hypercalcemia and neonatal severe hyperparathyroidism. Nat Genet. 1995 Dec; 11(4):389-94.
journal title abbreviation: Nat Genet
publication date: 1995-12-01T00:00:00
year: 1995
type: Academic Article
type: Article
type: Document
type: Information Resource

A disease locus for familial hypertrophic cardiomyopathy maps to chromosome 1q3.
PubMed Identifier: 7981753
author list: Watkins H, MacRae C, Thierfelder L, Chou YH, Frenneaux M, McKenna W, Seidman JG, Seidman CE
published in: Nature genetics
information resource reference: A disease locus for familial hypertrophic cardiomyopathy maps to chromosome 1q3. Nat Genet. 1993 Apr; 3(4):333-7.
journal title abbreviation: Nat Genet
publication date: 1993-04-01T00:00:00
year: 1993
type: Academic Article
type: Article
type: Document
type: Information Resource

Biochemistry and genetics of Klebsiella pneumoniae mutant strains unable to fix N2.
PubMed Identifier: 1090602
author list: St John RT, Johnston HM, Seidman C, Garfinkel D, Gordon JK, Shah VK, Brill WJ
published in: Journal of bacteriology
information resource reference: Biochemistry and genetics of Klebsiella pneumoniae mutant strains unable to fix N2. J Bacteriol. 1975 Mar; 121(3):759-65.
journal title abbreviation: J Bacteriol
publication date: 1975-03-01T00:00:00
year: 1975
type: Academic Article
type: Article
type: Document
type: Information Resource

An Ryr1I4895T mutation abolishes Ca2+ release channel function and delays development in homozygous offspring of a mutant mouse line.
PubMed Identifier: 18003898
author list: Zvaritch E, Depreux F, Kraeva N, Loy RE, Goonasekera SA, Boncompagni S, Boncompagi S, Kraev A, Gramolini AO, Dirksen RT, Franzini-Armstrong C, Seidman CE, Seidman JG, Maclennan DH
published in: Proceedings of the National Academy of Sciences of the United States of America
information resource reference: An Ryr1I4895T mutation abolishes Ca2+ release channel function and delays development in homozygous offspring of a mutant mouse line. Proc Natl Acad Sci U S A. 2007 Nov 20; 104(47):18537-42.
journal title abbreviation: Proc Natl Acad Sci U S A
publication date: 2007-11-14T00:00:00
year: 2007
type: Academic Article
type: Article
type: Document
type: Information Resource

Reversibility of PRKAG2 glycogen-storage cardiomyopathy and electrophysiological manifestations.
PubMed Identifier: 18158359
author list: Wolf CM, Arad M, Ahmad F, Sanbe A, Bernstein SA, Toka O, Konno T, Morley G, Robbins J, Seidman JG, Seidman CE, Berul CI
published in: Circulation
information resource reference: Reversibility of PRKAG2 glycogen-storage cardiomyopathy and electrophysiological manifestations. Circulation. 2008 Jan 15; 117(2):144-54.
journal title abbreviation: Circulation
publication date: 2007-12-24T00:00:00
year: 2007
type: Academic Article
type: Article
type: Document
type: Information Resource

Filter-based hybridization capture of subgenomes enables resequencing and copy-number detection.
PubMed Identifier: 19543287
author list: Herman DS, Hovingh GK, Iartchouk O, Rehm HL, Kucherlapati R, Seidman JG, Seidman CE
published in: Nature methods
information resource reference: Filter-based hybridization capture of subgenomes enables resequencing and copy-number detection. Nat Methods. 2009 Jul; 6(7):507-10.
journal title abbreviation: Nat Methods
publication date: 2009-06-21T00:00:00
year: 2009
type: Academic Article
type: Article
type: Document
type: Information Resource

Sarcomere gene mutations in hypertrophy and heart failure.
PubMed Identifier: 20559778
author list: Morita H, Nagai R, Seidman JG, Seidman CE
published in: Journal of cardiovascular translational research
information resource reference: Sarcomere gene mutations in hypertrophy and heart failure. J Cardiovasc Transl Res. 2010 Aug; 3(4):297-303.
journal title abbreviation: J Cardiovasc Transl Res
publication date: 2010-05-25T00:00:00
year: 2010
type: Academic Article
type: Article
type: Document
type: Information Resource

Myocardial fibrosis as an early manifestation of hypertrophic cardiomyopathy.
PubMed Identifier: 20818890
author list: Ho CY, López B, Coelho-Filho OR, Lakdawala NK, Cirino AL, Jarolim P, Kwong R, González A, Colan SD, Seidman JG, Díez J, Seidman CE
published in: The New England journal of medicine
information resource reference: Myocardial fibrosis as an early manifestation of hypertrophic cardiomyopathy. N Engl J Med. 2010 Aug 05; 363(6):552-63.
journal title abbreviation: N Engl J Med
publication date: 2010-08-05T00:00:00
year: 2010
type: Academic Article
type: Article
type: Document
type: Information Resource

The Good SHP2 Association: a porthole into the genetics of congenital heart disease.
PubMed Identifier: 22715277
author list: Gelb BD, Seidman CE
published in: Circulation. Cardiovascular genetics
information resource reference: The Good SHP2 Association: a porthole into the genetics of congenital heart disease. Circ Cardiovasc Genet. 2012 Jun; 5(3):271-3.
journal title abbreviation: Circ Cardiovasc Genet
publication date: 2012-06-01T00:00:00
year: 2012
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 11277
type: Authorship
author rank in publication: 1
linked author: Seidman, Christine
linked information resource: Nucleotide sequences of the human and mouse atrial natriuretic factor genes.

CLCN5 mutation Ser244Leu is associated with X-linked renal failure without X-linked recessive hypophosphatemic rickets.
PubMed Identifier: 9452997
author list: Kelleher CL, Buckalew VM, Frederickson ED, Rhodes DJ, Conner DA, Seidman JG, Seidman CE
published in: Kidney international
information resource reference: CLCN5 mutation Ser244Leu is associated with X-linked renal failure without X-linked recessive hypophosphatemic rickets. Kidney Int. 1998 Jan; 53(1):31-7.
journal title abbreviation: Kidney Int
publication date: 1998-01-01T00:00:00
year: 1998
type: Academic Article
type: Article
type: Document
type: Information Resource

The Bjornstad syndrome (sensorineural hearing loss and pili torti) disease gene maps to chromosome 2q34-36.
PubMed Identifier: 9545407
author list: Lubianca Neto JF, Lu L, Eavey RD, Flores MA, Caldera RM, Sangwatanaroj S, Schott JJ, McDonough B, Santos JI, Seidman CE, Seidman JG
published in: American journal of human genetics
information resource reference: The Bjornstad syndrome (sensorineural hearing loss and pili torti) disease gene maps to chromosome 2q34-36. Am J Hum Genet. 1998 May; 62(5):1107-12.
journal title abbreviation: Am J Hum Genet
publication date: 1998-05-01T00:00:00
year: 1998
type: Academic Article
type: Article
type: Document
type: Information Resource

Familial dilated cardiomyopathy locus maps to chromosome 2q31.
PubMed Identifier: 10051295
author list: Siu BL, Niimura H, Osborne JA, Fatkin D, MacRae C, Solomon S, Benson DW, Seidman JG, Seidman CE
published in: Circulation
information resource reference: Familial dilated cardiomyopathy locus maps to chromosome 2q31. Circulation. 1999 Mar 02; 99(8):1022-6.
journal title abbreviation: Circulation
publication date: 1999-03-02T00:00:00
year: 1999
type: Academic Article
type: Article
type: Document
type: Information Resource

An alpha-cardiac myosin heavy chain gene mutation impairs contraction and relaxation function of cardiac myocytes.
PubMed Identifier: 10330263
author list: Kim SJ, Iizuka K, Kelly RA, Geng YJ, Bishop SP, Yang G, Kudej A, McConnell BK, Seidman CE, Seidman JG, Vatner SF
published in: The American journal of physiology
information resource reference: An alpha-cardiac myosin heavy chain gene mutation impairs contraction and relaxation function of cardiac myocytes. Am J Physiol. 1999 05; 276(5):H1780-7.
journal title abbreviation: Am J Physiol
publication date: 1999-05-01T00:00:00
year: 1999
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 11528
type: Authorship
author rank in publication: 13
linked author: Seidman, Christine
linked information resource: Mutation in the transcriptional coactivator EYA4 causes dilated cardiomyopathy and sensorineural hearing loss.

Mutations of TTN, encoding the giant muscle filament titin, cause familial dilated cardiomyopathy.
PubMed Identifier: 11788824
author list: Gerull B, Gramlich M, Atherton J, McNabb M, Trombitás K, Sasse-Klaassen S, Seidman JG, Seidman C, Granzier H, Labeit S, Frenneaux M, Thierfelder L
published in: Nature genetics
information resource reference: Mutations of TTN, encoding the giant muscle filament titin, cause familial dilated cardiomyopathy. Nat Genet. 2002 Feb; 30(2):201-4.
journal title abbreviation: Nat Genet
publication date: 2002-01-14T00:00:00
year: 2002
type: Academic Article
type: Article
type: Document
type: Information Resource

Sarcomere protein gene mutations in hypertrophic cardiomyopathy of the elderly.
PubMed Identifier: 11815426
author list: Niimura H, Patton KK, McKenna WJ, Soults J, Maron BJ, Seidman JG, Seidman CE
published in: Circulation
information resource reference: Sarcomere protein gene mutations in hypertrophic cardiomyopathy of the elderly. Circulation. 2002 Jan 29; 105(4):446-51.
journal title abbreviation: Circulation
publication date: 2002-01-29T00:00:00
year: 2002
type: Academic Article
type: Article
type: Document
type: Information Resource

Transcription factor haploinsufficiency: when half a loaf is not enough.
PubMed Identifier: 11854316
author list: Seidman JG, Seidman C
published in: The Journal of clinical investigation
information resource reference: Transcription factor haploinsufficiency: when half a loaf is not enough. J Clin Invest. 2002 Feb; 109(4):451-5.
journal title abbreviation: J Clin Invest
publication date: 2002-02-01T00:00:00
year: 2002
type: Academic Article
type: Article
type: Document
type: Information Resource

Single-gene mutations and increased left ventricular wall thickness in the community: the Framingham Heart Study.
PubMed Identifier: 16754800
author list: Morita H, Larson MG, Barr SC, Vasan RS, O'Donnell CJ, Hirschhorn JN, Levy D, Corey D, Seidman CE, Seidman JG, Benjamin EJ
published in: Circulation
information resource reference: Single-gene mutations and increased left ventricular wall thickness in the community: the Framingham Heart Study. Circulation. 2006 Jun 13; 113(23):2697-705.
journal title abbreviation: Circulation
publication date: 2006-06-05T00:00:00
year: 2006
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1124413
type: Authorship
author rank in publication: 6
linked author: Seidman, Christine
linked information resource: Sex differences in gene expression in response to ischemia in the human left ventricular myocardium.

Sex differences in gene expression in response to ischemia in the human left ventricular myocardium.
PubMed Identifier: 30649309
author list: Stone G, Choi A, Meritxell O, Gorham J, Heydarpour M, Seidman CE, Seidman JG, Aranki SF, Body SC, Carey VJ, Raby BA, Stranger BE, Muehlschlegel JD
published in: Human molecular genetics
information resource reference: Sex differences in gene expression in response to ischemia in the human left ventricular myocardium. Hum Mol Genet. 2019 05 15; 28(10):1682-1693.
journal title abbreviation: Hum Mol Genet
publication date: 2019-05-15T00:00:00
year: 2019
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1127643
type: Authorship
author rank in publication: 17
linked author: Seidman, Christine
linked information resource: Hypertrophic cardiomyopathy mutations in MYBPC3 dysregulate myosin.

Hypertrophic cardiomyopathy mutations in MYBPC3 dysregulate myosin.
PubMed Identifier: 30674652
author list: Toepfer CN, Wakimoto H, Garfinkel AC, McDonough B, Liao D, Jiang J, Tai AC, Gorham JM, Lunde IG, Lun M, Lynch TL, McNamara JW, Sadayappan S, Redwood CS, Watkins HC, Seidman JG, Seidman CE
published in: Science translational medicine
information resource reference: Hypertrophic cardiomyopathy mutations in MYBPC3 dysregulate myosin. Sci Transl Med. 2019 01 23; 11(476).
journal title abbreviation: Sci Transl Med
publication date: 2019-01-23T00:00:00
year: 2019
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1129285
type: Authorship
author rank in publication: 16
linked author: Seidman, Christine
linked information resource: SarcTrack.

SarcTrack.
PubMed Identifier: 30700234
author list: Toepfer CN, Sharma A, Cicconet M, Garfinkel AC, Mücke M, Neyazi M, Willcox JAL, Agarwal R, Schmid M, Rao J, Ewoldt J, Pourquié O, Chopra A, Chen CS, Seidman JG, Seidman CE
published in: Circulation research
information resource reference: SarcTrack. Circ Res. 2019 04 12; 124(8):1172-1183.
journal title abbreviation: Circ Res
publication date: 2019-04-12T00:00:00
year: 2019
type: Academic Article
type: Article
type: Document
type: Information Resource

Photoaffinity labeling of the alpha 1-adrenergic receptor using an 125I-labeled aryl azide analogue of prazosin.
PubMed Identifier: 6089880
author list: Seidman CE, Hess HJ, Homcy CJ, Graham RM
published in: Biochemistry
information resource reference: Photoaffinity labeling of the alpha 1-adrenergic receptor using an 125I-labeled aryl azide analogue of prazosin. Biochemistry. 1984 Jul 31; 23(16):3765-70.
journal title abbreviation: Biochemistry
publication date: 1984-07-31T00:00:00
year: 1984
type: Academic Article
type: Article
type: Document
type: Information Resource

Homozygosity mapping of the gene for alkaptonuria to chromosome 3q2.
PubMed Identifier: 8252048
author list: Pollak MR, Chou YH, Cerda JJ, Steinmann B, La Du BN, Seidman JG, Seidman CE
published in: Nature genetics
information resource reference: Homozygosity mapping of the gene for alkaptonuria to chromosome 3q2. Nat Genet. 1993 Oct; 5(2):201-4.
journal title abbreviation: Nat Genet
publication date: 1993-10-01T00:00:00
year: 1993
type: Academic Article
type: Article
type: Document
type: Information Resource

Left ventricular hypertrophy and morphology in familial hypertrophic cardiomyopathy associated with mutations of the beta-myosin heavy chain gene.
PubMed Identifier: 8335820
author list: Solomon SD, Wolff S, Watkins H, Ridker PM, Come P, McKenna WJ, Seidman CE, Lee RT
published in: Journal of the American College of Cardiology
information resource reference: Left ventricular hypertrophy and morphology in familial hypertrophic cardiomyopathy associated with mutations of the beta-myosin heavy chain gene. J Am Coll Cardiol. 1993 Aug; 22(2):498-505.
journal title abbreviation: J Am Coll Cardiol
publication date: 1993-08-01T00:00:00
year: 1993
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 109206
type: Authorship
author rank in publication: 1
linked author: Seidman, Christine
linked information resource: Photoaffinity labeling of the alpha 1-adrenergic receptor using an 125I-labeled aryl azide analogue of prazosin.

Activin type II receptor signaling in cardiac aging and heart failure.
PubMed Identifier: 30842316
author list: Roh JD, Hobson R, Chaudhari V, Quintero P, Yeri A, Benson M, Xiao C, Zlotoff D, Bezzerides V, Houstis N, Platt C, Damilano F, Lindman BR, Elmariah S, Biersmith M, Lee SJ, Seidman CE, Seidman JG, Gerszten RE, Lach-Trifilieff E, Glass DJ, Rosenzweig A
published in: Science translational medicine
information resource reference: Activin type II receptor signaling in cardiac aging and heart failure. Sci Transl Med. 2019 03 06; 11(482).
journal title abbreviation: Sci Transl Med
publication date: 2019-03-06T00:00:00
year: 2019
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1134885
type: Authorship
author rank in publication: 17
linked author: Seidman, Christine
linked information resource: Activin type II receptor signaling in cardiac aging and heart failure.

Heart Defects, Congenital
MeSH DescriptorUI: D006330
MeSH semantic group name: Disorders
number of authors: 904
number of publications: 4943
uniqueness weight: 0.291762
type: Concept

Myocytes, Cardiac
MeSH DescriptorUI: D032383
MeSH semantic group name: Anatomy
number of authors: 611
number of publications: 1862
uniqueness weight: 0.50496
type: Concept

Sarcomeres
MeSH DescriptorUI: D012518
MeSH semantic group name: Anatomy
number of authors: 121
number of publications: 394
uniqueness weight: 0.790963
type: Concept

Authorship 1145339
type: Authorship
author rank in publication: 11
linked author: Seidman, Christine
linked information resource: Response by Ho et al to Letter Regarding Article, "Genotype and Lifetime Burden of Disease in Hypertrophic Cardiomyopathy: Insights From the Sarcomeric Human Cardiomyopathy Registry (SHaRe)".

Authorship 1146570
type: Authorship
author rank in publication: 16
linked author: Seidman, Christine
linked information resource: ORE identifies extreme expression effects enriched for rare variants.

Authorship 1143846
type: Authorship
author rank in publication: 2
linked author: Seidman, Christine
linked information resource: Advances in the Genetic Basis and Pathogenesis of Sarcomere Cardiomyopathies.

Authorship 1145165
type: Authorship
author rank in publication: 52
linked author: Seidman, Christine
linked information resource: Genetic Variants Associated With Cancer Therapy-Induced Cardiomyopathy.

Advances in the Genetic Basis and Pathogenesis of Sarcomere Cardiomyopathies.
PubMed Identifier: 30978303
author list: Yotti R, Seidman CE, Seidman JG
published in: Annual review of genomics and human genetics
information resource reference: Advances in the Genetic Basis and Pathogenesis of Sarcomere Cardiomyopathies. Annu Rev Genomics Hum Genet. 2019 08 31; 20:129-153.
journal title abbreviation: Annu Rev Genomics Hum Genet
publication date: 2019-04-12T00:00:00
year: 2019
type: Academic Article
type: Article
type: Document
type: Information Resource

Genetic Variants Associated With Cancer Therapy-Induced Cardiomyopathy.
PubMed Identifier: 30987448
author list: Garcia-Pavia P, Kim Y, Restrepo-Cordoba MA, Lunde IG, Wakimoto H, Smith AM, Toepfer CN, Getz K, Gorham J, Patel P, Ito K, Willcox JA, Arany Z, Li J, Owens AT, Govind R, Nuñez B, Mazaika E, Bayes-Genis A, Walsh R, Finkelman B, Lupon J, Whiffin N, Serrano I, Midwinter W, Wilk A, Bardaji A, Ingold N, Buchan R, Tayal U, Pascual-Figal DA, de Marvao A, Ahmad M, Garcia-Pinilla JM, Pantazis A, Dominguez F, John Baksi A, O'Regan DP, Rosen SD, Prasad SK, Lara-Pezzi E, Provencio M, Lyon AR, Alonso-Pulpon L, Cook SA, DePalma SR, Barton PJR, Aplenc R, Seidman JG, Ky B, Ware JS, Seidman CE
published in: Circulation
information resource reference: Genetic Variants Associated With Cancer Therapy-Induced Cardiomyopathy. Circulation. 2019 07 02; 140(1):31-41.
journal title abbreviation: Circulation
publication date: 2019-04-16T00:00:00
year: 2019
type: Academic Article
type: Article
type: Document
type: Information Resource

ORE identifies extreme expression effects enriched for rare variants.
PubMed Identifier: 30903145
author list: Richter F, Hoffman GE, Manheimer KB, Patel N, Sharp AJ, McKean D, Morton SU, DePalma S, Gorham J, Kitaygorodksy A, Porter GA, Giardini A, Shen Y, Chung WK, Seidman JG, Seidman CE, Schadt EE, Gelb BD
published in: Bioinformatics (Oxford, England)
information resource reference: ORE identifies extreme expression effects enriched for rare variants. Bioinformatics. 2019 10 15; 35(20):3906-3912.
journal title abbreviation: Bioinformatics
publication date: 2019-10-15T00:00:00
year: 2019
type: Academic Article
type: Article
type: Document
type: Information Resource

Response by Ho et al to Letter Regarding Article, "Genotype and Lifetime Burden of Disease in Hypertrophic Cardiomyopathy: Insights From the Sarcomeric Human Cardiomyopathy Registry (SHaRe)".
PubMed Identifier: 30883221
author list: Ho CY, Day SM, Ashley EA, Michels M, Pereira AC, Jacoby D, Lakdawala NK, Ware JS, Helms AS, Colan SD, Seidman CE, Olivotto I
published in: Circulation
information resource reference: Response by Ho et al to Letter Regarding Article, "Genotype and Lifetime Burden of Disease in Hypertrophic Cardiomyopathy: Insights From the Sarcomeric Human Cardiomyopathy Registry (SHaRe)". Circulation. 2019 03 19; 139(12):1559-1560.
journal title abbreviation: Circulation
publication date: 2019-03-19T00:00:00
year: 2019
type: Academic Article
type: Article
type: Document
type: Information Resource

Cardiomyopathy, Dilated
MeSH DescriptorUI: D002311
MeSH semantic group name: Disorders
number of authors: 334
number of publications: 900
uniqueness weight: 0.618289
type: Concept

Cardiomyopathy, Hypertrophic
MeSH DescriptorUI: D002312
MeSH semantic group name: Disorders
number of authors: 370
number of publications: 1429
uniqueness weight: 0.49728
type: Concept

Authorship 118177
type: Authorship
author rank in publication: 8
linked author: Seidman, Christine
linked information resource: QTL influencing autoimmune diabetes and encephalomyelitis map to a 0.15-cM region containing Il2.

Genetics
type: Department
type: Organization

Medicine
type: Department
type: Organization

Pediatrics
type: Department
type: Organization

Cardiology
type: Division
type: Organization

Genetics
type: Division
type: Organization

Brigham and Women's Hospital
type: Organization

Boston Children's Hospital
type: Organization

Harvard Medical School
type: Organization

Aikawa, Elena
eCommons Login: ER4
first name: Elena
last name: Aikawa
full name: Elena Aikawa, M.D., Ph.D.
has faculty rank: Full Professor
latitude: 42.33837200000000
longitude: -71.10326900000000
photo: https://connects.catalyst.harvard.edu/Profiles/profile/Modules/CustomViewPersonGeneralInfo/PhotoHandler.ashx
Person ID: 79704
person in primary position: Professor of Medicine
type: Agent
type: Person
preferred title: Professor of Medicine

Leopold, Jane
eCommons Login: JAL42
first name: Jane
last name: Leopold
full name: Jane Anne Leopold, M.D.
has faculty rank: Associate Professor
latitude: 42.33837200000000
longitude: -71.10326900000000
Person ID: 85108
person in primary position: Associate Professor of Medicine
type: Agent
type: Person
preferred title: Associate Professor of Medicine

Solomon, Scott
eCommons Login: SDS3
first name: Scott
last name: Solomon
full name: Scott David Solomon, M.D.
has faculty rank: Full Professor
latitude: 42.33510370000000
longitude: -71.10616490000000
Person ID: 37443
person in primary position: Professor of Medicine
type: Agent
type: Person
preferred title: Professor of Medicine

Morton, Sarah
eCommons Login: SUM2
first name: Sarah
last name: Morton
full name: Sarah Uhler Morton, M.D.,Ph.D.
has faculty rank: Assistant Professor
latitude: 42.33743600000000
longitude: -71.10544700000000
Person ID: 90442
person in primary position: Assistant Professor of Pediatrics
type: Agent
type: Person
preferred title: Assistant Professor of Pediatrics

Authorship 1155612
type: Authorship
author rank in publication: 4
linked author: Seidman, Christine
linked information resource: Novel Therapies for Prevention and Early Treatment of Cardiomyopathies.

Novel Therapies for Prevention and Early Treatment of Cardiomyopathies.
PubMed Identifier: 31120825
author list: Repetti GG, Toepfer CN, Seidman JG, Seidman CE
published in: Circulation research
information resource reference: Novel Therapies for Prevention and Early Treatment of Cardiomyopathies. Circ Res. 2019 05 24; 124(11):1536-1550.
journal title abbreviation: Circ Res
publication date: 2019-05-24T00:00:00
year: 2019
type: Academic Article
type: Article
type: Document
type: Information Resource

Wakimoto, Hiroko
eCommons Login: HW72
first name: Hiroko
last name: Wakimoto
full name: Hiroko Wakimoto, M.D., Ph.D.
has faculty rank: Instructor
latitude: 42.33743600000000
longitude: -71.10544700000000
Person ID: 57550
person in primary position: Instructor in Genetics
type: Agent
type: Person
preferred title: Instructor in Genetics

Feinberg, Mark
eCommons Login: MWF1
first name: Mark
last name: Feinberg
full name: Mark W. Feinberg, M.D.
has faculty rank: Full Professor
latitude: 42.33837200000000
longitude: -71.10326900000000
Person ID: 19817
person in primary position: Professor of Medicine
type: Agent
type: Person
preferred title: Professor of Medicine

Authorship 1158547
type: Authorship
author rank in publication: 52
linked author: Seidman, Christine
linked information resource: The Translational Landscape of the Human Heart.

The Translational Landscape of the Human Heart.
PubMed Identifier: 31155234
author list: van Heesch S, Witte F, Schneider-Lunitz V, Schulz JF, Adami E, Faber AB, Kirchner M, Maatz H, Blachut S, Sandmann CL, Kanda M, Worth CL, Schafer S, Calviello L, Merriott R, Patone G, Hummel O, Wyler E, Obermayer B, Mücke MB, Lindberg EL, Trnka F, Memczak S, Schilling M, Felkin LE, Barton PJR, Quaife NM, Vanezis K, Diecke S, Mukai M, Mah N, Oh SJ, Kurtz A, Schramm C, Schwinge D, Sebode M, Harakalova M, Asselbergs FW, Vink A, de Weger RA, Viswanathan S, Widjaja AA, Gärtner-Rommel A, Milting H, Dos Remedios C, Knosalla C, Mertins P, Landthaler M, Vingron M, Linke WA, Seidman JG, Seidman CE, Rajewsky N, Ohler U, Cook SA, Hubner N
published in: Cell
information resource reference: The Translational Landscape of the Human Heart. Cell. 2019 06 27; 178(1):242-260.e29.
journal title abbreviation: Cell
publication date: 2019-05-30T00:00:00
year: 2019
type: Academic Article
type: Article
type: Document
type: Information Resource

Ho, Carolyn
eCommons Login: CYH3
first name: Carolyn
last name: Ho
full name: Carolyn Yung Ho, M.D.
has faculty rank: Full Professor
latitude: 42.33510370000000
longitude: -71.10616490000000
Person ID: 65728
person in primary position: Professor of Medicine
type: Agent
type: Person
preferred title: Professor of Medicine

Croce, Kevin
eCommons Login: KJC5
first name: Kevin
last name: Croce
full name: Kevin James Croce, M.D.,Ph.D.
has faculty rank: Assistant Professor
latitude: 42.33837200000000
longitude: -71.10326900000000
Person ID: 2987
person in primary position: Assistant Professor of Medicine
type: Agent
type: Person
preferred title: Assistant Professor of Medicine

Alkuraya, Fowzan
eCommons Login: FSA2
first name: Fowzan
last name: Alkuraya
full name: Fowzan Sami Alkuraya, M.B.,B.S.
has faculty rank: Instructor
latitude: 42.33837200000000
longitude: -71.10326900000000
Person ID: 41121
person in primary position: Instructor in Pediatrics
type: Agent
type: Person
preferred title: Instructor in Pediatrics

Lakdawala, Neal
eCommons Login: NL16
first name: Neal
last name: Lakdawala
full name: Neal Lakdawala, M.D.
has faculty rank: Assistant Professor
latitude: 42.33510370000000
longitude: -71.10616490000000
Person ID: 53971
person in primary position: Assistant Professor of Medicine
type: Agent
type: Person
preferred title: Assistant Professor of Medicine

Authorship 133490
type: Authorship
author rank in publication: 12
linked author: Seidman, Christine
linked information resource: A molecular pathway including Id2, Tbx5, and Nkx2-5 required for cardiac conduction system development.

Authorship 1160733
type: Authorship
author rank in publication: 10
linked author: Seidman, Christine
linked information resource: Abnormal Left-Hemispheric Sulcal Patterns Correlate with Neurodevelopmental Outcomes in Subjects with Single Ventricular Congenital Heart Disease.

Abnormal Left-Hemispheric Sulcal Patterns Correlate with Neurodevelopmental Outcomes in Subjects with Single Ventricular Congenital Heart Disease.
PubMed Identifier: 31216004
author list: Morton SU, Maleyeff L, Wypij D, Yun HJ, Newburger JW, Bellinger DC, Roberts AE, Rivkin MJ, Seidman JG, Seidman CE, Grant PE, Im K
published in: Cerebral cortex (New York, N.Y. : 1991)
information resource reference: Abnormal Left-Hemispheric Sulcal Patterns Correlate with Neurodevelopmental Outcomes in Subjects with Single Ventricular Congenital Heart Disease. Cereb Cortex. 2020 03 21; 30(2):476-487.
journal title abbreviation: Cereb Cortex
publication date: 2020-03-21T00:00:00
year: 2020
type: Academic Article
type: Article
type: Document
type: Information Resource

selected publications
maximum weight: 1
minimum weight: 1
number of connections: 535
predicate node: https://connects.catalyst.harvard.edu/Profiles/profile/113
predicate: selected publications
type: Network

research areas
maximum weight: 9.83663
minimum weight: 0.00141443
number of connections: 1282
predicate node: https://connects.catalyst.harvard.edu/Profiles/profile/217
predicate: research areas
type: Network

coauthor of
maximum weight: 22.4401
minimum weight: 0.00377292
number of connections: 253
predicate node: https://connects.catalyst.harvard.edu/Profiles/profile/363
predicate: coauthor of
type: Network

similar to
maximum weight: 308.094
minimum weight: 36.1894
number of connections: 60
predicate node: https://connects.catalyst.harvard.edu/Profiles/profile/494
predicate: similar to
type: Network

Authorship 152518
type: Authorship
author rank in publication: 19
linked author: Seidman, Christine
linked information resource: https://connects.catalyst.harvard.edu/Profiles/profile/823399

Handy, Diane
eCommons Login: DEH8
first name: Diane
last name: Handy
full name: Diane Elizabeth Handy, Ph.D.
has faculty rank: Assistant Professor
latitude: 42.33837200000000
longitude: -71.10326900000000
Person ID: 76190
person in primary position: Assistant Professor of Medicine
type: Agent
type: Person
preferred title: Assistant Professor of Medicine

Seidman, Jonathan
eCommons Login: JGS12
first name: Jonathan
last name: Seidman
full name: Jonathan G. Seidman, Ph.D.
has faculty rank: Full Professor
latitude: 42.33837200000000
longitude: -71.10326900000000
Person ID: 60374
person in primary position: Henrietta B. and Frederick H. Bugher Foundation Professor of Genetics
type: Agent
type: Person
preferred title: Henrietta B. and Frederick H. Bugher Foundation Professor of Genetics

Authorship 139346
type: Authorship
author rank in publication: 7
linked author: Seidman, Christine
linked information resource: N488I mutation of the gamma2-subunit results in bidirectional changes in AMP-activated protein kinase activity.

Authorship 139571
type: Authorship
author rank in publication: 2
linked author: Seidman, Christine
linked information resource: A contemporary approach to hypertrophic cardiomyopathy.

Authorship 1165707
type: Authorship
author rank in publication: 9
linked author: Seidman, Christine
linked information resource: Histone H2B monoubiquitination regulates heart development via epigenetic control of cilia motility.

Histone H2B monoubiquitination regulates heart development via epigenetic control of cilia motility.
PubMed Identifier: 31235600
author list: Robson A, Makova SZ, Barish S, Zaidi S, Mehta S, Drozd J, Jin SC, Gelb BD, Seidman CE, Chung WK, Lifton RP, Khokha MK, Brueckner M
published in: Proceedings of the National Academy of Sciences of the United States of America
information resource reference: Histone H2B monoubiquitination regulates heart development via epigenetic control of cilia motility. Proc Natl Acad Sci U S A. 2019 07 09; 116(28):14049-14054.
journal title abbreviation: Proc Natl Acad Sci U S A
publication date: 2019-06-24T00:00:00
year: 2019
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 140332
type: Authorship
author rank in publication: 8
linked author: Seidman, Christine
linked information resource: Eya4 regulation of Na+/K+-ATPase is required for sensory system development in zebrafish.

Authorship 120533
type: Authorship
author rank in publication: 2
linked author: Seidman, Christine
linked information resource: HLA and other immunogenetic approaches to the study of diseases in man.

Authorship 1172558
type: Authorship
author rank in publication: 14
linked author: Seidman, Christine
linked information resource: Paternal-age-related de novo mutations and risk for five disorders.

Paternal-age-related de novo mutations and risk for five disorders.
PubMed Identifier: 31292440
author list: Taylor JL, Debost JPG, Morton SU, Wigdor EM, Heyne HO, Lal D, Howrigan DP, Bloemendal A, Larsen JT, Kosmicki JA, Weiner DJ, Homsy J, Seidman JG, Seidman CE, Agerbo E, McGrath JJ, Mortensen PB, Petersen L, Daly MJ, Robinson EB
published in: Nature communications
information resource reference: Paternal-age-related de novo mutations and risk for five disorders. Nat Commun. 2019 07 10; 10(1):3043.
journal title abbreviation: Nat Commun
publication date: 2019-07-10T00:00:00
year: 2019
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 14193
type: Authorship
author rank in publication: 6
linked author: Seidman, Christine
linked information resource: Adult Hallervorden-Spatz syndrome simulating amyotrophic lateral sclerosis.

Authorship 131185
type: Authorship
author rank in publication: 6
linked author: Seidman, Christine
linked information resource: Sporadic hypertrophic cardiomyopathy due to de novo myosin mutations.

Authorship 1331
type: Authorship
author rank in publication: 11
linked author: Seidman, Christine
linked information resource: https://connects.catalyst.harvard.edu/Profiles/profile/794045

Authorship 114842
type: Authorship
author rank in publication: 11
linked author: Seidman, Christine
linked information resource: The L-type calcium channel inhibitor diltiazem prevents cardiomyopathy in a mouse model.

Authorship 1187755
type: Authorship
author rank in publication: 13
linked author: Seidman, Christine
linked information resource: The uptake of family screening in hypertrophic cardiomyopathy and an online video intervention to facilitate family communication.

The uptake of family screening in hypertrophic cardiomyopathy and an online video intervention to facilitate family communication.
PubMed Identifier: 31482667
author list: Harris S, Cirino AL, Carr CW, Tafessu HM, Parmar S, Greenberg JO, Szent-Gyorgyi LE, Ghazinouri R, Glowny MG, McNeil K, Kaynor EF, Neumann C, Seidman CE, MacRae CA, Ho CY, Lakdawala NK
published in: Molecular genetics & genomic medicine
information resource reference: The uptake of family screening in hypertrophic cardiomyopathy and an online video intervention to facilitate family communication. Mol Genet Genomic Med. 2019 11; 7(11):e940.
journal title abbreviation: Mol Genet Genomic Med
publication date: 2019-09-03T00:00:00
year: 2019
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 153715
type: Authorship
author rank in publication: 8
linked author: Seidman, Christine
linked information resource: Hereditary postlingual sensorineural hearing loss mapping to chromosome Xq21.

Authorship 1191778
type: Authorship
author rank in publication: 11
linked author: Seidman, Christine
linked information resource: Yin Yang 1 Suppresses Dilated Cardiomyopathy and Cardiac Fibrosis Through Regulation of Bmp7 and Ctgf.

Yin Yang 1 Suppresses Dilated Cardiomyopathy and Cardiac Fibrosis Through Regulation of Bmp7 and Ctgf.
PubMed Identifier: 31495264
author list: Tan CY, Wong JX, Chan PS, Tan H, Liao D, Chen W, Tan LW, Ackers-Johnson M, Wakimoto H, Seidman JG, Seidman CE, Lunde IG, Zhu F, Hu Q, Bian J, Wang JW, Foo RS, Jiang J
published in: Circulation research
information resource reference: Yin Yang 1 Suppresses Dilated Cardiomyopathy and Cardiac Fibrosis Through Regulation of Bmp7 and Ctgf. Circ Res. 2019 10 11; 125(9):834-846.
journal title abbreviation: Circ Res
publication date: 2019-09-09T00:00:00
year: 2019
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 144631
type: Authorship
author rank in publication: 12
linked author: Seidman, Christine
linked information resource: Gene mutations in apical hypertrophic cardiomyopathy.

Authorship 163428
type: Authorship
author rank in publication: 10
linked author: Seidman, Christine
linked information resource: Cardiac myosin missense mutations cause dilated cardiomyopathy in mouse models and depress molecular motor function.

Authorship 1197554
type: Authorship
author rank in publication: 16
linked author: Seidman, Christine
linked information resource: De novo and recessive forms of congenital heart disease have distinct genetic and phenotypic landscapes.

De novo and recessive forms of congenital heart disease have distinct genetic and phenotypic landscapes.
PubMed Identifier: 31624253
author list: Watkins WS, Hernandez EJ, Wesolowski S, Bisgrove BW, Sunderland RT, Lin E, Lemmon G, Demarest BL, Miller TA, Bernstein D, Brueckner M, Chung WK, Gelb BD, Goldmuntz E, Newburger JW, Seidman CE, Shen Y, Yost HJ, Yandell M, Tristani-Firouzi M
published in: Nature communications
information resource reference: De novo and recessive forms of congenital heart disease have distinct genetic and phenotypic landscapes. Nat Commun. 2019 10 17; 10(1):4722.
journal title abbreviation: Nat Commun
publication date: 2019-10-17T00:00:00
year: 2019
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 109632
type: Authorship
author rank in publication: 4
linked author: Seidman, Christine
linked information resource: The cloning of extracellular Ca(2+)-sensing receptors from parathyroid and kidney: molecular mechanisms of extracellular Ca(2+)-sensing.

Authorship 165197
type: Authorship
author rank in publication: 5
linked author: Seidman, Christine
linked information resource: Sudden death due to troponin T mutations.

Assistant Professor of Medicine
is primary position: true
position in department: Medicine
position in division: Cardiology
sort order: 1
type: Position
HR job title: Assistant Professor of Medicine
position in organization: Brigham and Women's Hospital

Instructor in Genetics
is primary position: true
position in department: Genetics
position in division: https://connects.catalyst.harvard.edu/Profiles/profile/1229413
sort order: 1
type: Position
HR job title: Instructor in Genetics
position in organization: Harvard Medical School

Associate Professor of Medicine
is primary position: true
position in department: Medicine
position in division: Cardiology
sort order: 1
type: Position
HR job title: Associate Professor of Medicine
position in organization: Brigham and Women's Hospital

Professor of Medicine
is primary position: true
position in department: Medicine
position in division: Cardiology
sort order: 1
type: Position
HR job title: Professor of Medicine
position in organization: Brigham and Women's Hospital

Assistant Professor of Medicine
is primary position: true
position in department: Medicine
position in division: Cardiology
sort order: 1
type: Position
HR job title: Assistant Professor of Medicine
position in organization: Brigham and Women's Hospital

Authorship 1208224
type: Authorship
author rank in publication: 12
linked author: Seidman, Christine
linked information resource: Association of Race With Disease Expression and Clinical Outcomes Among Patients With Hypertrophic Cardiomyopathy.

Authorship 1208310
type: Authorship
author rank in publication: 5
linked author: Seidman, Christine
linked information resource: Precision Medicine in the Management of Dilated Cardiomyopathy: JACC State-of-the-Art Review.

Association of Race With Disease Expression and Clinical Outcomes Among Patients With Hypertrophic Cardiomyopathy.
PubMed Identifier: 31799990
author list: Eberly LA, Day SM, Ashley EA, Jacoby DL, Jefferies JL, Colan SD, Rossano JW, Semsarian C, Pereira AC, Olivotto I, Ingles J, Seidman CE, Channaoui N, Cirino AL, Han L, Ho CY, Lakdawala NK
published in: JAMA cardiology
information resource reference: Association of Race With Disease Expression and Clinical Outcomes Among Patients With Hypertrophic Cardiomyopathy. JAMA Cardiol. 2020 01 01; 5(1):83-91.
journal title abbreviation: JAMA Cardiol
publication date: 2020-01-01T00:00:00
year: 2020
type: Academic Article
type: Article
type: Document
type: Information Resource

Precision Medicine in the Management of Dilated Cardiomyopathy: JACC State-of-the-Art Review.
PubMed Identifier: 31806137
author list: Fatkin D, Huttner IG, Kovacic JC, Seidman JG, Seidman CE
published in: Journal of the American College of Cardiology
information resource reference: Precision Medicine in the Management of Dilated Cardiomyopathy: JACC State-of-the-Art Review. J Am Coll Cardiol. 2019 12 10; 74(23):2921-2938.
journal title abbreviation: J Am Coll Cardiol
publication date: 2019-12-10T00:00:00
year: 2019
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1210910
type: Authorship
author rank in publication: 2
linked author: Seidman, Christine
linked information resource: Scientists on the Spot: Putting a halt to hypertrophic cardiomyopathy.

Scientists on the Spot: Putting a halt to hypertrophic cardiomyopathy.
PubMed Identifier: 31828295
author list: Meli AC, Seidman CE
published in: Cardiovascular research
information resource reference: Scientists on the Spot: Putting a halt to hypertrophic cardiomyopathy. Cardiovasc Res. 2020 03 01; 116(3):e42-e43.
journal title abbreviation: Cardiovasc Res
publication date: 2020-03-01T00:00:00
year: 2020
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 14599
type: Authorship
author rank in publication: 3
linked author: Seidman, Christine
linked information resource: Proposal for contemporary screening strategies in families with hypertrophic cardiomyopathy.

Authorship 1221282
type: Authorship
author rank in publication: 28
linked author: Seidman, Christine
linked information resource: Myosin Sequestration Regulates Sarcomere Function, Cardiomyocyte Energetics, and Metabolism, Informing the Pathogenesis of Hypertrophic Cardiomyopathy.

Myosin Sequestration Regulates Sarcomere Function, Cardiomyocyte Energetics, and Metabolism, Informing the Pathogenesis of Hypertrophic Cardiomyopathy.
PubMed Identifier: 31983222
author list: Toepfer CN, Garfinkel AC, Venturini G, Wakimoto H, Repetti G, Alamo L, Sharma A, Agarwal R, Ewoldt JK, Cloonan P, Letendre J, Lun M, Olivotto I, Colan S, Ashley E, Jacoby D, Michels M, Redwood CS, Watkins HC, Day SM, Staples JF, Padrón R, Chopra A, Ho CY, Chen CS, Pereira AC, Seidman JG, Seidman CE
published in: Circulation
information resource reference: Myosin Sequestration Regulates Sarcomere Function, Cardiomyocyte Energetics, and Metabolism, Informing the Pathogenesis of Hypertrophic Cardiomyopathy. Circulation. 2020 03 10; 141(10):828-842.
journal title abbreviation: Circulation
publication date: 2020-01-27T00:00:00
year: 2020
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1227490
type: Authorship
author rank in publication: 30
linked author: Seidman, Christine
linked information resource: Correction: Exome-wide association study reveals novel susceptibility genes to sporadic dilated cardiomyopathy.

Correction: Exome-wide association study reveals novel susceptibility genes to sporadic dilated cardiomyopathy.
PubMed Identifier: 32059048
author list: Esslinger U, Garnier S, Korniat A, Proust C, Kararigas G, Müller-Nurasyid M, Empana JP, Morley MP, Perret C, Stark K, Bick AG, Prasad SK, Kriebel J, Li J, Tiret L, Strauch K, O'Regan DP, Marguiles KB, Seidman JG, Boutouyrie P, Lacolley P, Jouven X, Hengstenberg C, Komajda M, Hakonarson H, Isnard R, Arbustini E, Grallert H, Cook SA, Seidman CE, Regitz-Zagrosek V, Cappola TP, Charron P, Cambien F, Villard E
published in: PloS one
information resource reference: Correction: Exome-wide association study reveals novel susceptibility genes to sporadic dilated cardiomyopathy. PLoS One. 2020; 15(2):e0229472.
journal title abbreviation: PLoS One
publication date: 2020-02-14T00:00:00
year: 2020
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 172392
type: Authorship
author rank in publication: 9
linked author: Seidman, Christine
linked information resource: Familial dilated cardiomyopathy locus maps to chromosome 2q31.

Authorship 172571
type: Authorship
author rank in publication: 6
linked author: Seidman, Christine
linked information resource: Biosynthesis and secretion of proatrial natriuretic factor by cultured rat cardiocytes.

Authorship 1243466
type: Authorship
author rank in publication: 9
linked author: Seidman, Christine
linked information resource: Hypertrophic cardiomyopathy in myosin-binding protein C (MYBPC3) Icelandic founder mutation carriers.

Authorship 1243265
type: Authorship
author rank in publication: 22
linked author: Seidman, Christine
linked information resource: EM-mosaic detects mosaic point mutations that contribute to congenital heart disease.

Hypertrophic cardiomyopathy in myosin-binding protein C (MYBPC3) Icelandic founder mutation carriers.
PubMed Identifier: 32341788
author list: Adalsteinsdottir B, Burke M, Maron BJ, Danielsen R, Lopez B, Diez J, Jarolim P, Seidman J, Seidman CE, Ho CY, Gunnarsson GT
published in: Open heart
information resource reference: Hypertrophic cardiomyopathy in myosin-binding protein C (MYBPC3) Icelandic founder mutation carriers. Open Heart. 2020; 7(1):e001220.
journal title abbreviation: Open Heart
publication date: 2020-04-05T00:00:00
year: 2020
type: Academic Article
type: Article
type: Document
type: Information Resource

EM-mosaic detects mosaic point mutations that contribute to congenital heart disease.
PubMed Identifier: 32349777
author list: Hsieh A, Morton SU, Willcox JAL, Gorham JM, Tai AC, Qi H, DePalma S, McKean D, Griffin E, Manheimer KB, Bernstein D, Kim RW, Newburger JW, Porter GA, Srivastava D, Tristani-Firouzi M, Brueckner M, Lifton RP, Goldmuntz E, Gelb BD, Chung WK, Seidman CE, Seidman JG, Shen Y
published in: Genome medicine
information resource reference: EM-mosaic detects mosaic point mutations that contribute to congenital heart disease. Genome Med. 2020 04 29; 12(1):42.
journal title abbreviation: Genome Med
publication date: 2020-04-29T00:00:00
year: 2020
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 172700
type: Authorship
author rank in publication: 2
linked author: Seidman, Christine
linked information resource: Progress in familial hypertrophic cardiomyopathy: molecular genetic analyses in the original family studied by Teare.

Authorship 1245623
type: Authorship
author rank in publication: 21
linked author: Seidman, Christine
linked information resource: Systems Analysis Implicates WAVE2 Complex in the Pathogenesis of Developmental Left-Sided Obstructive Heart Defects.

Systems Analysis Implicates WAVE2 Complex in the Pathogenesis of Developmental Left-Sided Obstructive Heart Defects.
PubMed Identifier: 32368696
author list: Edwards JJ, Rouillard AD, Fernandez NF, Wang Z, Lachmann A, Shankaran SS, Bisgrove BW, Demarest B, Turan N, Srivastava D, Bernstein D, Deanfield J, Giardini A, Porter G, Kim R, Roberts AE, Newburger JW, Goldmuntz E, Brueckner M, Lifton RP, Seidman CE, Chung WK, Tristani-Firouzi M, Yost HJ, Ma'ayan A, Gelb BD
published in: JACC. Basic to translational science
information resource reference: Systems Analysis Implicates WAVE2 Complex in the Pathogenesis of Developmental Left-Sided Obstructive Heart Defects. JACC Basic Transl Sci. 2020 Apr; 5(4):376-386.
journal title abbreviation: JACC Basic Transl Sci
publication date: 2020-04-08T00:00:00
year: 2020
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1246678
type: Authorship
author rank in publication: 8
linked author: Seidman, Christine
linked information resource: Congenital Heart Defects Due to TAF1 Missense Variants.

Congenital Heart Defects Due to TAF1 Missense Variants.
PubMed Identifier: 32396742
author list: Morton SU, Agarwal R, Madden JA, Genetti CA, Brownstein CA, López-Giráldez F, Choi J, Seidman CE, Seidman JG, Lyon GJ, Agrawal PB
published in: Circulation. Genomic and precision medicine
information resource reference: Congenital Heart Defects Due to TAF1 Missense Variants. Circ Genom Precis Med. 2020 06; 13(3):e002843.
journal title abbreviation: Circ Genom Precis Med
publication date: 2020-05-12T00:00:00
year: 2020
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 201637
type: Authorship
author rank in publication: 5
linked author: Seidman, Christine
linked information resource: Compound and double mutations in patients with hypertrophic cardiomyopathy: implications for genetic testing and counselling.

Authorship 201709
type: Authorship
author rank in publication: 12
linked author: Seidman, Christine
linked information resource: Somatic events modify hypertrophic cardiomyopathy pathology and link hypertrophy to arrhythmia.

Authorship 1251535
type: Authorship
author rank in publication: 8
linked author: Seidman, Christine
linked information resource: Marked Up-Regulation of ACE2 in Hearts of Patients With Obstructive Hypertrophic Cardiomyopathy: Implications for SARS-CoV-2-Mediated COVID-19.

Marked Up-Regulation of ACE2 in Hearts of Patients With Obstructive Hypertrophic Cardiomyopathy: Implications for SARS-CoV-2-Mediated COVID-19.
PubMed Identifier: 32448590
author list: Bos JM, Hebl VB, Oberg AL, Sun Z, Herman DS, Teekakirikul P, Seidman JG, Seidman CE, Dos Remedios CG, Maleszewski JJ, Schaff HV, Dearani JA, Noseworthy PA, Friedman PA, Ommen SR, Brozovich FV, Ackerman MJ
published in: Mayo Clinic proceedings
information resource reference: Marked Up-Regulation of ACE2 in Hearts of Patients With Obstructive Hypertrophic Cardiomyopathy: Implications for SARS-CoV-2-Mediated COVID-19. Mayo Clin Proc. 2020 07; 95(7):1354-1368.
journal title abbreviation: Mayo Clin Proc
publication date: 2020-04-28T00:00:00
year: 2020
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 138516
type: Authorship
author rank in publication: 15
linked author: Seidman, Christine
linked information resource: Loss-of-function mutations in the PRPS1 gene cause a type of nonsyndromic X-linked sensorineural deafness, DFN2.

Authorship 1253175
type: Authorship
author rank in publication: 31
linked author: Seidman, Christine
linked information resource: Expanding the clinical and genetic spectrum of ALPK3 variants: Phenotypes identified in pediatric cardiomyopathy patients and adults with heterozygous variants.

Authorship 1253345
type: Authorship
author rank in publication: 17
linked author: Seidman, Christine
linked information resource: Complement genes contribute sex-biased vulnerability in diverse disorders.

Expanding the clinical and genetic spectrum of ALPK3 variants: Phenotypes identified in pediatric cardiomyopathy patients and adults with heterozygous variants.
PubMed Identifier: 32480058
author list: Herkert JC, Verhagen JMA, Yotti R, Haghighi A, Phelan DG, James PA, Brown NJ, Stutterd C, Macciocca I, Leong K, Bulthuis MLC, van Bever Y, van Slegtenhorst MA, Boven LG, Roberts AE, Agarwal R, Seidman J, Lakdawala NK, Fernández-Avilés F, Burke MA, Pierpont ME, Braunlin E, ?aglayan AO, Barge-Schaapveld DQCM, Birnie E, van Osch-Gevers L, van Langen IM, Jongbloed JDH, Lockhart PJ, Amor DJ, Seidman CE, van de Laar IMBH
published in: American heart journal
information resource reference: Expanding the clinical and genetic spectrum of ALPK3 variants: Phenotypes identified in pediatric cardiomyopathy patients and adults with heterozygous variants. Am Heart J. 2020 07; 225:108-119.
journal title abbreviation: Am Heart J
publication date: 2020-04-21T00:00:00
year: 2020
type: Academic Article
type: Article
type: Document
type: Information Resource

Complement genes contribute sex-biased vulnerability in diverse disorders.
PubMed Identifier: 32499649
author list: Kamitaki N, Sekar A, Handsaker RE, de Rivera H, Tooley K, Morris DL, Taylor KE, Whelan CW, Tombleson P, Loohuis LMO, Boehnke M, Kimberly RP, Kaufman KM, Harley JB, Langefeld CD, Seidman CE, Pato MT, Pato CN, Ophoff RA, Graham RR, Criswell LA, Vyse TJ, McCarroll SA
published in: Nature
information resource reference: Complement genes contribute sex-biased vulnerability in diverse disorders. Nature. 2020 06; 582(7813):577-581.
journal title abbreviation: Nature
publication date: 2020-05-11T00:00:00
year: 2020
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 179015
type: Authorship
author rank in publication: 11
linked author: Seidman, Christine
linked information resource: https://connects.catalyst.harvard.edu/Profiles/profile/1043563

Authorship 1262616
type: Authorship
author rank in publication: 14
linked author: Seidman, Christine
linked information resource: BET bromodomain proteins regulate transcriptional reprogramming in genetic dilated cardiomyopathy.

Authorship 1263908
type: Authorship
author rank in publication: 34
linked author: Seidman, Christine
linked information resource: Genomic analyses implicate noncoding de novo variants in congenital heart disease.

BET bromodomain proteins regulate transcriptional reprogramming in genetic dilated cardiomyopathy.
PubMed Identifier: 32603312
author list: Antolic A, Wakimoto H, Jiao Z, Gorham JM, DePalma SR, Lemieux ME, Conner DA, Lee DY, Qi J, Seidman JG, Bradner JE, Brown JD, Haldar SM, Seidman CE, Burke MA
published in: JCI insight
information resource reference: BET bromodomain proteins regulate transcriptional reprogramming in genetic dilated cardiomyopathy. JCI Insight. 2020 08 06; 5(15).
journal title abbreviation: JCI Insight
publication date: 2020-08-06T00:00:00
year: 2020
type: Academic Article
type: Article
type: Document
type: Information Resource

Genomic analyses implicate noncoding de novo variants in congenital heart disease.
PubMed Identifier: 32601476
author list: Richter F, Morton SU, Kim SW, Kitaygorodsky A, Wasson LK, Chen KM, Zhou J, Qi H, Patel N, DePalma SR, Parfenov M, Homsy J, Gorham JM, Manheimer KB, Velinder M, Farrell A, Marth G, Schadt EE, Kaltman JR, Newburger JW, Giardini A, Goldmuntz E, Brueckner M, Kim R, Porter GA, Bernstein D, Chung WK, Srivastava D, Tristani-Firouzi M, Troyanskaya OG, Dickel DE, Shen Y, Seidman JG, Seidman CE, Gelb BD
published in: Nature genetics
information resource reference: Genomic analyses implicate noncoding de novo variants in congenital heart disease. Nat Genet. 2020 08; 52(8):769-777.
journal title abbreviation: Nat Genet
publication date: 2020-06-29T00:00:00
year: 2020
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 154673
type: Authorship
author rank in publication: 1
linked author: Seidman, Christine
linked information resource: Cis-acting sequences that modulate atrial natriuretic factor gene expression.

Authorship 15686
type: Authorship
author rank in publication: 4
linked author: Seidman, Christine
linked information resource: Genetic evaluation of cardiomyopathy--a Heart Failure Society of America practice guideline.

Authorship 182888
type: Authorship
author rank in publication: 1
linked author: Seidman, Christine
linked information resource: Leptospirosis.

Authorship 1278251
type: Authorship
author rank in publication: 42
linked author: Seidman, Christine
linked information resource: Genetic Studies of Hypertrophic Cardiomyopathy in Singaporeans Identify Variants in TNNI3 and TNNT2 That Are Common in Chinese Patients.

Authorship 1277319
type: Authorship
author rank in publication: 33
linked author: Seidman, Christine
linked information resource: De Novo Damaging Variants, Clinical Phenotypes, and Post-Operative Outcomes in Congenital Heart Disease.

Genetic Studies of Hypertrophic Cardiomyopathy in Singaporeans Identify Variants in TNNI3 and TNNT2 That Are Common in Chinese Patients.
PubMed Identifier: 32815737
author list: Pua CJ, Tham N, Chin CWL, Walsh R, Khor CC, Toepfer CN, Repetti GG, Garfinkel AC, Ewoldt JF, Cloonan P, Chen CS, Lim SQ, Cai J, Loo LY, Kong SC, Chiang CWK, Whiffin N, de Marvao A, Lio PM, Hii AA, Yang CX, Le TT, Bylstra Y, Lim WK, Teo JX, Padilha K, Silva GV, Pan B, Govind R, Buchan RJ, Barton PJR, Tan P, Foo R, Yip JWL, Wong RCC, Chan WX, Pereira AC, Tang HC, Jamuar SS, Ware JS, Seidman JG, Seidman CE, Cook SA
published in: Circulation. Genomic and precision medicine
information resource reference: Genetic Studies of Hypertrophic Cardiomyopathy in Singaporeans Identify Variants in TNNI3 and TNNT2 That Are Common in Chinese Patients. Circ Genom Precis Med. 2020 10; 13(5):424-434.
journal title abbreviation: Circ Genom Precis Med
publication date: 2020-08-20T00:00:00
year: 2020
type: Academic Article
type: Article
type: Document
type: Information Resource

De Novo Damaging Variants, Clinical Phenotypes, and Post-Operative Outcomes in Congenital Heart Disease.
PubMed Identifier: 32812804
author list: Boskovski MT, Homsy J, Nathan M, Sleeper LA, Morton S, Manheimer KB, Tai A, Gorham J, Lewis M, Swartz M, Alfieris GM, Bacha EA, Karimi M, Meyer D, Nguyen K, Bernstein D, Romano-Adesman A, Porter GA, Goldmuntz E, Chung WK, Srivastava D, Kaltman JR, Tristani-Firouzi M, Lifton R, Roberts AE, Gaynor JW, Gelb BD, Kim R, Seidman JG, Brueckner M, Mayer JE, Newburger JW, Seidman CE
published in: Circulation. Genomic and precision medicine
information resource reference: De Novo Damaging Variants, Clinical Phenotypes, and Post-Operative Outcomes in Congenital Heart Disease. Circ Genom Precis Med. 2020 08; 13(4):e002836.
journal title abbreviation: Circ Genom Precis Med
publication date: 2020-06-30T00:00:00
year: 2020
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1281664
type: Authorship
author rank in publication: 14
linked author: Seidman, Christine
linked information resource: Founder Mutation in N Terminus of Cardiac Troponin I Causes Malignant Hypertrophic Cardiomyopathy.

Founder Mutation in N Terminus of Cardiac Troponin I Causes Malignant Hypertrophic Cardiomyopathy.
PubMed Identifier: 32885985
author list: Fahed AC, Nemer G, Bitar FF, Arnaout S, Abchee AB, Batrawi M, Khalil A, Abou Hassan OK, DePalma SR, McDonough B, Arabi MT, Ware JS, Seidman JG, Seidman CE
published in: Circulation. Genomic and precision medicine
information resource reference: Founder Mutation in N Terminus of Cardiac Troponin I Causes Malignant Hypertrophic Cardiomyopathy. Circ Genom Precis Med. 2020 10; 13(5):444-452.
journal title abbreviation: Circ Genom Precis Med
publication date: 2020-09-04T00:00:00
year: 2020
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 199742
type: Authorship
author rank in publication: 10
linked author: Seidman, Christine
linked information resource: The Bjornstad syndrome (sensorineural hearing loss and pili torti) disease gene maps to chromosome 2q34-36.

Authorship 191744
type: Authorship
author rank in publication: 8
linked author: Seidman, Christine
linked information resource: A disease locus for familial hypertrophic cardiomyopathy maps to chromosome 1q3.

Authorship 1290595
type: Authorship
author rank in publication: 30
linked author: Seidman, Christine
linked information resource: Cells of the adult human heart.

Cells of the adult human heart.
PubMed Identifier: 32971526
author list: Litvinuková M, Talavera-López C, Maatz H, Reichart D, Worth CL, Lindberg EL, Kanda M, Polanski K, Heinig M, Lee M, Nadelmann ER, Roberts K, Tuck L, Fasouli ES, DeLaughter DM, McDonough B, Wakimoto H, Gorham JM, Samari S, Mahbubani KT, Saeb-Parsy K, Patone G, Boyle JJ, Zhang H, Zhang H, Viveiros A, Oudit GY, Bayraktar OA, Seidman JG, Seidman CE, Noseda M, Hubner N, Teichmann SA
published in: Nature
information resource reference: Cells of the adult human heart. Nature. 2020 12; 588(7838):466-472.
journal title abbreviation: Nature
publication date: 2020-09-24T00:00:00
year: 2020
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 192626
type: Authorship
author rank in publication: 7
linked author: Seidman, Christine
linked information resource: Cardiac myosin binding protein C phosphorylation is cardioprotective.

Authorship 207560
type: Authorship
author rank in publication: 12
linked author: Seidman, Christine
linked information resource: A gene for non-syndromic autosomal dominant progressive postlingual sensorineural hearing loss maps to chromosome 14q12-13.

Authorship 156151
type: Authorship
author rank in publication: 4
linked author: Seidman, Christine
linked information resource: Sarcomere gene mutations in hypertrophy and heart failure.

Authorship 1295162
type: Authorship
author rank in publication: 23
linked author: Seidman, Christine
linked information resource: Association of Damaging Variants in Genes With Increased Cancer Risk Among Patients With Congenital Heart Disease.

Authorship 1297631
type: Authorship
author rank in publication: 27
linked author: Seidman, Christine
linked information resource: GATA6 mutations in hiPSCs inform mechanisms for maldevelopment of the heart, pancreas, and diaphragm.

Association of Damaging Variants in Genes With Increased Cancer Risk Among Patients With Congenital Heart Disease.
PubMed Identifier: 33084842
author list: Morton SU, Shimamura A, Newburger PE, Opotowsky AR, Quiat D, Pereira AC, Jin SC, Gurvitz M, Brueckner M, Chung WK, Shen Y, Bernstein D, Gelb BD, Giardini A, Goldmuntz E, Kim RW, Lifton RP, Porter GA, Srivastava D, Tristani-Firouzi M, Newburger JW, Seidman JG, Seidman CE
published in: JAMA cardiology
information resource reference: Association of Damaging Variants in Genes With Increased Cancer Risk Among Patients With Congenital Heart Disease. JAMA Cardiol. 2021 04 01; 6(4):457-462.
journal title abbreviation: JAMA Cardiol
publication date: 2021-04-01T00:00:00
year: 2021
type: Academic Article
type: Article
type: Document
type: Information Resource

GATA6 mutations in hiPSCs inform mechanisms for maldevelopment of the heart, pancreas, and diaphragm.
PubMed Identifier: 33054971
author list: Sharma A, Wasson LK, Willcox JA, Morton SU, Gorham JM, DeLaughter DM, Neyazi M, Schmid M, Agarwal R, Jang MY, Toepfer CN, Ward T, Kim Y, Pereira AC, DePalma SR, Tai A, Kim S, Conner D, Bernstein D, Gelb BD, Chung WK, Goldmuntz E, Porter G, Tristani-Firouzi M, Srivastava D, Seidman JG, Seidman CE
published in: eLife
information resource reference: GATA6 mutations in hiPSCs inform mechanisms for maldevelopment of the heart, pancreas, and diaphragm. Elife. 2020 10 15; 9.
journal title abbreviation: Elife
publication date: 2020-10-15T00:00:00
year: 2020
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 133957
type: Authorship
author rank in publication: 7
linked author: Seidman, Christine
linked information resource: Familial hypertrophic cardiomyopathy and atrial fibrillation caused by Arg663His beta-cardiac myosin heavy chain mutation.

Authorship 1302878
type: Authorship
author rank in publication: 18
linked author: Seidman, Christine
linked information resource: Rare genetic variation at transcription factor binding sites modulates local DNA methylation profiles.

Rare genetic variation at transcription factor binding sites modulates local DNA methylation profiles.
PubMed Identifier: 33216750
author list: Martin-Trujillo A, Patel N, Richter F, Jadhav B, Garg P, Morton SU, McKean DM, DePalma SR, Goldmuntz E, Gruber D, Kim R, Newburger JW, Porter GA, Giardini A, Bernstein D, Tristani-Firouzi M, Seidman JG, Seidman CE, Chung WK, Gelb BD, Sharp AJ
published in: PLoS genetics
information resource reference: Rare genetic variation at transcription factor binding sites modulates local DNA methylation profiles. PLoS Genet. 2020 11; 16(11):e1009189.
journal title abbreviation: PLoS Genet
publication date: 2020-11-20T00:00:00
year: 2020
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 147813
type: Authorship
author rank in publication: 6
linked author: Seidman, Christine
linked information resource: A locus for inherited focal segmental glomerulosclerosis maps to chromosome 19q13.

Associations Between Female Sex, Sarcomere Variants, and Clinical Outcomes in Hypertrophic Cardiomyopathy.
PubMed Identifier: 33284039
author list: Lakdawala NK, Olivotto I, Day SM, Han L, Ashley EA, Michels M, Ingles J, Semsarian C, Jacoby D, Jefferies JL, Colan SD, Pereira AC, Rossano JW, Wittekind S, Ware JS, Saberi S, Helms AS, Cirino AL, Leinwand LA, Seidman CE, Ho CY
published in: Circulation. Genomic and precision medicine
information resource reference: Associations Between Female Sex, Sarcomere Variants, and Clinical Outcomes in Hypertrophic Cardiomyopathy. Circ Genom Precis Med. 2021 02; 14(1):e003062.
journal title abbreviation: Circ Genom Precis Med
publication date: 2020-12-07T00:00:00
year: 2020
type: Academic Article
type: Article
type: Document
type: Information Resource

Modeling Human TBX5 Haploinsufficiency Predicts Regulatory Networks for Congenital Heart Disease.
PubMed Identifier: 33321106
author list: Kathiriya IS, Rao KS, Iacono G, Devine WP, Blair AP, Hota SK, Lai MH, Garay BI, Thomas R, Gong HZ, Wasson LK, Goyal P, Sukonnik T, Hu KM, Akgun GA, Bernard LD, Akerberg BN, Gu F, Li K, Speir ML, Haeussler M, Pu WT, Stuart JM, Seidman CE, Seidman JG, Heyn H, Bruneau BG
published in: Developmental cell
information resource reference: Modeling Human TBX5 Haploinsufficiency Predicts Regulatory Networks for Congenital Heart Disease. Dev Cell. 2021 02 08; 56(3):292-309.e9.
journal title abbreviation: Dev Cell
publication date: 2020-12-14T00:00:00
year: 2020
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1310061
type: Authorship
author rank in publication: 20
linked author: Seidman, Christine
linked information resource: Associations Between Female Sex, Sarcomere Variants, and Clinical Outcomes in Hypertrophic Cardiomyopathy.

Authorship 1311028
type: Authorship
author rank in publication: 24
linked author: Seidman, Christine
linked information resource: Modeling Human TBX5 Haploinsufficiency Predicts Regulatory Networks for Congenital Heart Disease.

Authorship 160491
type: Authorship
author rank in publication: 5
linked author: Seidman, Christine
linked information resource: A human MSX1 homeodomain missense mutation causes selective tooth agenesis.

Mechanisms of Congenital Heart Disease Caused by NAA15 Haploinsufficiency.
PubMed Identifier: 33557580
author list: Ward T, Tai W, Morton S, Impens F, Van Damme P, Van Haver D, Timmerman E, Venturini G, Zhang K, Jang MY, Willcox JAL, Haghighi A, Gelb BD, Chung WK, Goldmuntz E, Porter GA, Lifton RP, Brueckner M, Yost HJ, Bruneau BG, Gorham J, Kim Y, Pereira A, Homsy J, Benson CC, DePalma SR, Varland S, Chen CS, Arnesen T, Gevaert K, Seidman C, Seidman JG
published in: Circulation research
information resource reference: Mechanisms of Congenital Heart Disease Caused by NAA15 Haploinsufficiency. Circ Res. 2021 04 16; 128(8):1156-1169.
journal title abbreviation: Circ Res
publication date: 2021-02-09T00:00:00
year: 2021
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1327643
type: Authorship
author rank in publication: 31
linked author: Seidman, Christine
linked information resource: Mechanisms of Congenital Heart Disease Caused by NAA15 Haploinsufficiency.

Authorship 243028
type: Authorship
author rank in publication: 12
linked author: Seidman, Christine
linked information resource: Mutations in sarcomere protein genes as a cause of dilated cardiomyopathy.

Authorship 199711
type: Authorship
author rank in publication: 4
linked author: Seidman, Christine
linked information resource: Electrophysiological abnormalities and arrhythmias in alpha MHC mutant familial hypertrophic cardiomyopathy mice.

Discordant clinical features of identical hypertrophic cardiomyopathy twins.
PubMed Identifier: 33658374
author list: Repetti GG, Kim Y, Pereira AC, Ingles J, Russell MW, Lakdawala NK, Ho CY, Day S, Semsarian C, McDonough B, DePalma SR, Quiat D, Green EM, Seidman CE, Seidman JG
published in: Proceedings of the National Academy of Sciences of the United States of America
information resource reference: Discordant clinical features of identical hypertrophic cardiomyopathy twins. Proc Natl Acad Sci U S A. 2021 03 09; 118(10).
journal title abbreviation: Proc Natl Acad Sci U S A
publication date: 2021-03-09T00:00:00
year: 2021
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1336328
type: Authorship
author rank in publication: 2
linked author: Seidman, Christine
linked information resource: Conquering Atherosclerotic Cardiovascular Disease - 50 Years of Progress.

Authorship 1336231
type: Authorship
author rank in publication: 14
linked author: Seidman, Christine
linked information resource: Discordant clinical features of identical hypertrophic cardiomyopathy twins.

Conquering Atherosclerotic Cardiovascular Disease - 50 Years of Progress.
PubMed Identifier: 33657686
author list: Gibbons GH, Seidman CE, Topol EJ
published in: The New England journal of medicine
information resource reference: Conquering Atherosclerotic Cardiovascular Disease - 50 Years of Progress. N Engl J Med. 2021 Mar 04; 384(9):785-788.
journal title abbreviation: N Engl J Med
publication date: 2021-02-27T00:00:00
year: 2021
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1337077
type: Authorship
author rank in publication: 26
linked author: Seidman, Christine
linked information resource: Genome-wide association analysis in dilated cardiomyopathy reveals two new players in systolic heart failure on chromosomes 3p25.1 and 22q11.23.

Genome-wide association analysis in dilated cardiomyopathy reveals two new players in systolic heart failure on chromosomes 3p25.1 and 22q11.23.
PubMed Identifier: 33677556
author list: Garnier S, Harakalova M, Weiss S, Mokry M, Regitz-Zagrosek V, Hengstenberg C, Cappola TP, Isnard R, Arbustini E, Cook SA, van Setten J, Calis JJA, Hakonarson H, Morley MP, Stark K, Prasad SK, Li J, O'Regan DP, Grasso M, Müller-Nurasyid M, Meitinger T, Empana JP, Strauch K, Waldenberger M, Marguiles KB, Seidman CE, Kararigas G, Meder B, Haas J, Boutouyrie P, Lacolley P, Jouven X, Erdmann J, Blankenberg S, Wichter T, Ruppert V, Tavazzi L, Dubourg O, Roizes G, Dorent R, de Groote P, Fauchier L, Trochu JN, Aupetit JF, Bilinska ZT, Germain M, Völker U, Hemerich D, Raji I, Bacq-Daian D, Proust C, Remior P, Gomez-Bueno M, Lehnert K, Maas R, Olaso R, Saripella GV, Felix SB, McGinn S, Duboscq-Bidot L, van Mil A, Besse C, Fontaine V, Blanché H, Ader F, Keating B, Curjol A, Boland A, Komajda M, Cambien F, Deleuze JF, Dörr M, Asselbergs FW, Villard E, Trégouët DA, Charron P
published in: European heart journal
information resource reference: Genome-wide association analysis in dilated cardiomyopathy reveals two new players in systolic heart failure on chromosomes 3p25.1 and 22q11.23. Eur Heart J. 2021 05 21; 42(20):2000-2011.
journal title abbreviation: Eur Heart J
publication date: 2021-05-21T00:00:00
year: 2021
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1350790
type: Authorship
author rank in publication: 10
linked author: Seidman, Christine
linked information resource: Genetic and Phenotypic Landscape of Peripartum Cardiomyopathy.

Genetic and Phenotypic Landscape of Peripartum Cardiomyopathy.
PubMed Identifier: 33874732
author list: Goli R, Li J, Brandimarto J, Levine LD, Riis V, McAfee Q, DePalma S, Haghighi A, Seidman JG, Seidman CE, Jacoby D, Macones G, Judge DP, Rana S, Margulies KB, Cappola TP, Alharethi R, Damp J, Hsich E, Elkayam U, Sheppard R, Alexis JD, Boehmer J, Kamiya C, Gustafsson F, Damm P, Ersbøll AS, Goland S, Hilfiker-Kleiner D, McNamara DM, Arany Z
published in: Circulation
information resource reference: Genetic and Phenotypic Landscape of Peripartum Cardiomyopathy. Circulation. 2021 05 11; 143(19):1852-1862.
journal title abbreviation: Circulation
publication date: 2021-04-20T00:00:00
year: 2021
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1356135
type: Authorship
author rank in publication: 15
linked author: Seidman, Christine
linked information resource: CalTrack: High-Throughput Automated Calcium Transient Analysis in Cardiomyocytes.

CalTrack: High-Throughput Automated Calcium Transient Analysis in Cardiomyocytes.
PubMed Identifier: 34018815
author list: Psaras Y, Margara F, Cicconet M, Sparrow AJ, Repetti GG, Schmid M, Steeples V, Wilcox JAL, Bueno-Orovio A, Redwood CS, Watkins HC, Robinson P, Rodriguez B, Seidman JG, Seidman CE, Toepfer CN
published in: Circulation research
information resource reference: CalTrack: High-Throughput Automated Calcium Transient Analysis in Cardiomyocytes. Circ Res. 2021 07 09; 129(2):326-341.
journal title abbreviation: Circ Res
publication date: 2021-05-21T00:00:00
year: 2021
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1358759
type: Authorship
author rank in publication: 12
linked author: Seidman, Christine
linked information resource: Isolation of Nuclei from Mammalian Cells and Tissues for Single-Nucleus Molecular Profiling.

Isolation of Nuclei from Mammalian Cells and Tissues for Single-Nucleus Molecular Profiling.
PubMed Identifier: 34043278
author list: Nadelmann ER, Gorham JM, Reichart D, Delaughter DM, Wakimoto H, Lindberg EL, Litvinukova M, Maatz H, Curran JJ, Ischiu Gutierrez D, Hübner N, Seidman CE, Seidman JG
published in: Current protocols
information resource reference: Isolation of Nuclei from Mammalian Cells and Tissues for Single-Nucleus Molecular Profiling. Curr Protoc. 2021 May; 1(5):e132.
journal title abbreviation: Curr Protoc
publication date: 2021-05-01T00:00:00
year: 2021
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 176360
type: Authorship
author rank in publication: 5
linked author: Seidman, Christine
linked information resource: Epigenetic repression of cardiac progenitor gene expression by Ezh2 is required for postnatal cardiac homeostasis.

Genomic frontiers in congenital heart disease.
PubMed Identifier: 34272501
author list: Morton SU, Quiat D, Seidman JG, Seidman CE
published in: Nature reviews. Cardiology
information resource reference: Genomic frontiers in congenital heart disease. Nat Rev Cardiol. 2022 01; 19(1):26-42.
journal title abbreviation: Nat Rev Cardiol
publication date: 2021-07-16T00:00:00
year: 2021
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1374273
type: Authorship
author rank in publication: 10
linked author: Seidman, Christine
linked information resource: Cardiomyocyte Proliferative Capacity Is Restricted in Mice With Lmna Mutation.

Authorship 1375326
type: Authorship
author rank in publication: 4
linked author: Seidman, Christine
linked information resource: Genomic frontiers in congenital heart disease.

Cardiomyocyte Proliferative Capacity Is Restricted in Mice With Lmna Mutation.
PubMed Identifier: 34250035
author list: Onoue K, Wakimoto H, Jiang J, Parfenov M, DePalma S, Conner D, Gorham J, McKean D, Seidman JG, Seidman CE, Saito Y
published in: Frontiers in cardiovascular medicine
information resource reference: Cardiomyocyte Proliferative Capacity Is Restricted in Mice With Lmna Mutation. Front Cardiovasc Med. 2021; 8:639148.
journal title abbreviation: Front Cardiovasc Med
publication date: 2021-06-23T00:00:00
year: 2021
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 158413
type: Authorship
author rank in publication: 7
linked author: Seidman, Christine
linked information resource: Regulation of murine fetal-placental calcium metabolism by the calcium-sensing receptor.

Authorship 1387045
type: Authorship
author rank in publication: 12
linked author: Seidman, Christine
linked information resource: Filamin C Cardiomyopathy Variants Cause Protein and Lysosome Accumulation.

Filamin C Cardiomyopathy Variants Cause Protein and Lysosome Accumulation.
PubMed Identifier: 34405687
author list: Agarwal R, Paulo JA, Toepfer CN, Ewoldt JK, Sundaram S, Chopra A, Zhang Q, Gorham J, DePalma SR, Chen CS, Gygi SP, Seidman CE, Seidman JG
published in: Circulation research
information resource reference: Filamin C Cardiomyopathy Variants Cause Protein and Lysosome Accumulation. Circ Res. 2021 09 17; 129(7):751-766.
journal title abbreviation: Circ Res
publication date: 2021-08-18T00:00:00
year: 2021
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1389892
type: Authorship
author rank in publication: 16
linked author: Seidman, Christine
linked information resource: Contribution of Noncanonical Splice Variants to TTN Truncating Variant Cardiomyopathy.

Authorship 1390853
type: Authorship
author rank in publication: 14
linked author: Seidman, Christine
linked information resource: LAMP2 Cardiomyopathy: Consequences of Impaired Autophagy in the Heart.

LAMP2 Cardiomyopathy: Consequences of Impaired Autophagy in the Heart.
PubMed Identifier: 34459252
author list: Alcalai R, Arad M, Wakimoto H, Yadin D, Gorham J, Wang L, Burns E, Maron BJ, Roberts WC, Konno T, Conner DA, Perez-Atayde AR, Seidman JG, Seidman CE
published in: Journal of the American Heart Association
information resource reference: LAMP2 Cardiomyopathy: Consequences of Impaired Autophagy in the Heart. J Am Heart Assoc. 2021 09 07; 10(17):e018829.
journal title abbreviation: J Am Heart Assoc
publication date: 2021-08-28T00:00:00
year: 2021
type: Academic Article
type: Article
type: Document
type: Information Resource

Contribution of Noncanonical Splice Variants to TTN Truncating Variant Cardiomyopathy.
PubMed Identifier: 34461741
author list: Patel PN, Ito K, Willcox JAL, Haghighi A, Jang MY, Gorham JM, DePalma SR, Lam L, McDonough B, Johnson R, Lakdawala NK, Roberts A, Barton PJR, Cook SA, Fatkin D, Seidman CE, Seidman JG
published in: Circulation. Genomic and precision medicine
information resource reference: Contribution of Noncanonical Splice Variants to TTN Truncating Variant Cardiomyopathy. Circ Genom Precis Med. 2021 10; 14(5):e003389.
journal title abbreviation: Circ Genom Precis Med
publication date: 2021-08-31T00:00:00
year: 2021
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1395703
type: Authorship
author rank in publication: 26
linked author: Seidman, Christine
linked information resource: Valsartan in early-stage hypertrophic cardiomyopathy: a randomized phase 2 trial.

Valsartan in early-stage hypertrophic cardiomyopathy: a randomized phase 2 trial.
PubMed Identifier: 34556856
author list: Ho CY, Day SM, Axelsson A, Russell MW, Zahka K, Lever HM, Pereira AC, Colan SD, Margossian R, Murphy AM, Canter C, Bach RG, Wheeler MT, Rossano JW, Owens AT, Bundgaard H, Benson L, Mestroni L, Taylor MRG, Patel AR, Wilmot I, Thrush P, Vargas JD, Soslow JH, Becker JR, Seidman CE, Lakdawala NK, Cirino AL, Burns KM, McMurray JJV, MacRae CA, Solomon SD, Orav EJ, Braunwald E
published in: Nature medicine
information resource reference: Valsartan in early-stage hypertrophic cardiomyopathy: a randomized phase 2 trial. Nat Med. 2021 10; 27(10):1818-1824.
journal title abbreviation: Nat Med
publication date: 2021-09-23T00:00:00
year: 2021
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 183195
type: Authorship
author rank in publication: 10
linked author: Seidman, Christine
linked information resource: Accelerated cardiomyopathy in mice with overexpression of cardiac G(s)alpha and a missense mutation in the alpha-myosin heavy chain.

Authorship 1398008
type: Authorship
author rank in publication: 10
linked author: Seidman, Christine
linked information resource: Probing the subcellular nanostructure of engineered human cardiomyocytes in 3D tissue.

Probing the subcellular nanostructure of engineered human cardiomyocytes in 3D tissue.
PubMed Identifier: 34567727
author list: Javor J, Ewoldt JK, Cloonan PE, Chopra A, Luu RJ, Freychet G, Zhernenkov M, Ludwig K, Seidman JG, Seidman CE, Chen CS, Bishop DJ
published in: Microsystems & nanoengineering
information resource reference: Probing the subcellular nanostructure of engineered human cardiomyocytes in 3D tissue. Microsyst Nanoeng. 2021; 7:10.
journal title abbreviation: Microsyst Nanoeng
publication date: 2021-01-27T00:00:00
year: 2021
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1403379
type: Authorship
author rank in publication: 15
linked author: Seidman, Christine
linked information resource: Plakophilin-2 truncating variants impair cardiac contractility by disrupting sarcomere stability and organization.

Plakophilin-2 truncating variants impair cardiac contractility by disrupting sarcomere stability and organization.
PubMed Identifier: 34652945
author list: Zhang K, Cloonan PE, Sundaram S, Liu F, Das SL, Ewoldt JK, Bays JL, Tomp S, Toepfer CN, Marsiglia JDC, Gorham J, Reichart D, Eyckmans J, Seidman JG, Seidman CE, Chen CS
published in: Science advances
information resource reference: Plakophilin-2 truncating variants impair cardiac contractility by disrupting sarcomere stability and organization. Sci Adv. 2021 Oct 15; 7(42):eabh3995.
journal title abbreviation: Sci Adv
publication date: 2021-10-15T00:00:00
year: 2021
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 215950
type: Authorship
author rank in publication: 9
linked author: Seidman, Christine
linked information resource: Single-gene mutations and increased left ventricular wall thickness in the community: the Framingham Heart Study.

Authorship 218153
type: Authorship
author rank in publication: 11
linked author: Seidman, Christine
linked information resource: A classic twin study of external ear malformations, including microtia.

Authorship 161568
type: Authorship
author rank in publication: 2
linked author: Seidman, Christine
linked information resource: Molecular medicine in the 21st century.

Authorship 1421667
type: Authorship
author rank in publication: 14
linked author: Seidman, Christine
linked information resource: https://connects.catalyst.harvard.edu/Profiles/profile/189862430

Authorship 1422666
type: Authorship
author rank in publication: 15
linked author: Seidman, Christine
linked information resource: Cell cycle defects underlie childhood-onset cardiomyopathy associated with Noonan syndrome.

https://connects.catalyst.harvard.edu/Profiles/profile/189862430
PubMed Identifier: 34969177
author list: de Boer RA, Heymans S, Backs J, Carrier L, Coats AJS, Dimmeler S, Eschenhagen T, Filippatos G, Gepstein L, Hulot JS, Knöll R, Kupatt C, Linke WA, Seidman CE, Tocchetti CG, van der Velden J, Walsh R, Seferovic PM, Thum T
published in: European journal of heart failure
information resource reference: Targeted therapies in genetic dilated and hypertrophic cardiomyopathies: from molecular mechanisms to therapeutic targets. A position paper from the Heart Failure Association (HFA) and the Working Group on Myocardial Function of the European Society of Cardiology (ESC). Eur J Heart Fail. 2022 03; 24(3):406-420.
journal title abbreviation: Eur J Heart Fail
publication date: 2022-01-14T00:00:00
year: 2022
type: Academic Article
type: Article
type: Document
type: Information Resource
label: Targeted therapies in genetic dilated and hypertrophic cardiomyopathies: from molecular mechanisms to therapeutic targets. A position paper from the Heart Failure Association (HFA) and the Working Group on Myocardial Function of the European Society of Cardiology (ESC).

Cell cycle defects underlie childhood-onset cardiomyopathy associated with Noonan syndrome.
PubMed Identifier: 34988410
author list: Meier AB, Raj Murthi S, Rawat H, Toepfer CN, Santamaria G, Schmid M, Mastantuono E, Schwarzmayr T, Berutti R, Cleuziou J, Ewert P, Görlach A, Klingel K, Laugwitz KL, Seidman CE, Seidman JG, Moretti A, Wolf CM
published in: iScience
information resource reference: Cell cycle defects underlie childhood-onset cardiomyopathy associated with Noonan syndrome. iScience. 2022 Jan 21; 25(1):103596.
journal title abbreviation: iScience
publication date: 2021-12-09T00:00:00
year: 2021
type: Academic Article
type: Article
type: Document
type: Information Resource

Kim, Yuri
eCommons Login: YK154
first name: Yuri
last name: Kim
full name: Yuri Kim, M.D., Ph.D.
has faculty rank: Assistant Professor
Person ID: 118883
person in primary position: Assistant Professor of Medicine
type: Agent
type: Person
preferred title: Assistant Professor of Medicine

Authorship 164816
type: Authorship
author rank in publication: 12
linked author: Seidman, Christine
linked information resource: Rescue of cardiomyocyte dysfunction by phospholamban ablation does not prevent ventricular failure in genetic hypertrophy.

Authorship 200198
type: Authorship
author rank in publication: 5
linked author: Seidman, Christine
linked information resource: Deficient cation channel regulation in neurons from mice with targeted disruption of the extracellular Ca2+-sensing receptor gene.

Authorship 23411
type: Authorship
author rank in publication: 12
linked author: Seidman, Christine
linked information resource: Mutations in the gene for cardiac myosin-binding protein C and late-onset familial hypertrophic cardiomyopathy.

Authorship 1431645
type: Authorship
author rank in publication: 20
linked author: Seidman, Christine
linked information resource: Genome-Wide De Novo Variants in Congenital Heart Disease Are Not Associated With Maternal Diabetes or Obesity.

Genome-Wide De Novo Variants in Congenital Heart Disease Are Not Associated With Maternal Diabetes or Obesity.
PubMed Identifier: 35130025
author list: Morton SU, Pereira AC, Quiat D, Richter F, Kitaygorodsky A, Hagen J, Bernstein D, Brueckner M, Goldmuntz E, Kim RW, Lifton RP, Porter GA, Tristani-Firouzi M, Chung WK, Roberts A, Gelb BD, Shen Y, Newburger JW, Seidman JG, Seidman CE
published in: Circulation. Genomic and precision medicine
information resource reference: Genome-Wide De Novo Variants in Congenital Heart Disease Are Not Associated With Maternal Diabetes or Obesity. Circ Genom Precis Med. 2022 04; 15(2):e003500.
journal title abbreviation: Circ Genom Precis Med
publication date: 2022-02-07T00:00:00
year: 2022
type: Academic Article
type: Article
type: Document
type: Information Resource

Genetics of cancer therapy-associated cardiotoxicity.
PubMed Identifier: 35358500
author list: Kim Y, Seidman JG, Seidman CE
published in: Journal of molecular and cellular cardiology
information resource reference: Genetics of cancer therapy-associated cardiotoxicity. J Mol Cell Cardiol. 2022 06; 167:85-91.
journal title abbreviation: J Mol Cell Cardiol
publication date: 2022-03-28T00:00:00
year: 2022
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1440227
type: Authorship
author rank in publication: 3
linked author: Seidman, Christine
linked information resource: Genetics of cancer therapy-associated cardiotoxicity.

Authorship 1440696
type: Authorship
author rank in publication: 20
linked author: Seidman, Christine
linked information resource: Transcription factor protein interactomes reveal genetic determinants in heart disease.

Transcription factor protein interactomes reveal genetic determinants in heart disease.
PubMed Identifier: 35182466
author list: Gonzalez-Teran B, Pittman M, Felix F, Thomas R, Richmond-Buccola D, Hüttenhain R, Choudhary K, Moroni E, Costa MW, Huang Y, Padmanabhan A, Alexanian M, Lee CY, Maven BEJ, Samse-Knapp K, Morton SU, McGregor M, Gifford CA, Seidman JG, Seidman CE, Gelb BD, Colombo G, Conklin BR, Black BL, Bruneau BG, Krogan NJ, Pollard KS, Srivastava D
published in: Cell
information resource reference: Transcription factor protein interactomes reveal genetic determinants in heart disease. Cell. 2022 03 03; 185(5):794-814.e30.
journal title abbreviation: Cell
publication date: 2022-02-18T00:00:00
year: 2022
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 273016
type: Authorship
author rank in publication: 2
linked author: Seidman, Christine
linked information resource: Alpha 1-adrenergic receptor mRNA level is regulated by norepinephrine in rabbit aortic smooth muscle cells.

Authorship 1445772
type: Authorship
author rank in publication: 5
linked author: Seidman, Christine
linked information resource: Engineering a living cardiac pump on a chip using high-precision fabrication.

Authorship 1446711
type: Authorship
author rank in publication: 23
linked author: Seidman, Christine
linked information resource: Neither cardiac mitochondrial DNA variation nor copy number contribute to congenital heart disease risk.

Neither cardiac mitochondrial DNA variation nor copy number contribute to congenital heart disease risk.
PubMed Identifier: 35397206
author list: Willcox JAL, Geiger JT, Morton SU, McKean D, Quiat D, Gorham JM, Tai AC, DePalma S, Bernstein D, Brueckner M, Chung WK, Giardini A, Goldmuntz E, Kaltman JR, Kim R, Newburger JW, Shen Y, Srivastava D, Tristani-Firouzi M, Gelb B, Porter GA, Seidman JG, Seidman CE
published in: American journal of human genetics
information resource reference: Neither cardiac mitochondrial DNA variation nor copy number contribute to congenital heart disease risk. Am J Hum Genet. 2022 05 05; 109(5):961-966.
journal title abbreviation: Am J Hum Genet
publication date: 2022-04-08T00:00:00
year: 2022
type: Academic Article
type: Article
type: Document
type: Information Resource

Engineering a living cardiac pump on a chip using high-precision fabrication.
PubMed Identifier: 35452278
author list: Michas C, Karakan MÇ, Nautiyal P, Seidman JG, Seidman CE, Agarwal A, Ekinci K, Eyckmans J, White AE, Chen CS
published in: Science advances
information resource reference: Engineering a living cardiac pump on a chip using high-precision fabrication. Sci Adv. 2022 Apr 22; 8(16):eabm3791.
journal title abbreviation: Sci Adv
publication date: 2022-04-22T00:00:00
year: 2022
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1451248
type: Authorship
author rank in publication: 47
linked author: Seidman, Christine
linked information resource: Genetic determinants of telomere length from 109,122 ancestrally diverse whole-genome sequences in TOPMed.

Authorship 1450868
type: Authorship
author rank in publication: 9
linked author: Seidman, Christine
linked information resource: Population Prevalence of Premature Truncating Variants in Plakophilin-2 and Association With Arrhythmogenic Right Ventricular Cardiomyopathy: A UK Biobank Analysis.

Authorship 1451818
type: Authorship
author rank in publication: 20
linked author: Seidman, Christine
linked information resource: An ancient founder mutation located between ROBO1 and ROBO2 is responsible for increased microtia risk in Amerindigenous populations.

Genetic determinants of telomere length from 109,122 ancestrally diverse whole-genome sequences in TOPMed.
PubMed Identifier: 35530816
author list: Taub MA, Conomos MP, Keener R, Iyer KR, Weinstock JS, Yanek LR, Lane J, Miller-Fleming TW, Brody JA, Raffield LM, McHugh CP, Jain D, Gogarten SM, Laurie CA, Keramati A, Arvanitis M, Smith AV, Heavner B, Barwick L, Becker LC, Bis JC, Blangero J, Bleecker ER, Burchard EG, Celedón JC, Chang YPC, Custer B, Darbar D, de las Fuentes L, DeMeo DL, Freedman BI, Garrett ME, Gladwin MT, Heckbert SR, Hidalgo BA, Irvin MR, Islam T, Johnson WC, Kaab S, Launer L, Lee J, Liu S, Moscati A, North KE, Peyser PA, Rafaels N, Seidman C, Weeks DE, Wen F, Wheeler MM, Williams LK, Yang IV, Zhao W, Aslibekyan S, Auer PL, Bowden DW, Cade BE, Chen Z, Cho MH, Cupples LA, Curran JE, Daya M, Deka R, Eng C, Fingerlin TE, Guo X, Hou L, Hwang SJ, Johnsen JM, Kenny EE, Levin AM, Liu C, Minster RL, Naseri T, Nouraie M, Reupena MS, Sabino EC, Smith JA, Smith NL, Su JL, Taylor JG, Telen MJ, Tiwari HK, Tracy RP, White MJ, Zhang Y, Wiggins KL, Weiss ST, Vasan RS, Taylor KD, Sinner MF, Silverman EK, Shoemaker MB, Sheu WH, Sciurba F, Schwartz DA, Rotter JI, Roden D, Redline S, Raby BA, Psaty BM, Peralta JM, Palmer ND, Nekhai S, Montgomery CG, Mitchell BD, Meyers DA, McGarvey ST, Mak AC, Loos RJ, Kumar R, Kooperberg C, Konkle BA, Kelly S, Kardia SL, Kaplan R, He J, Gui H, Gilliland FD, Gelb BD, Fornage M, Ellinor PT, de Andrade M, Correa A, Chen YI, Boerwinkle E, Barnes KC, Ashley-Koch AE, Arnett DK, Laurie CC, Abecasis G, Nickerson DA, Wilson JG, Rich SS, Levy D, Ruczinski I, Aviv A, Blackwell TW, Thornton T, O'Connell J, Cox NJ, Perry JA, Armanios M, Battle A, Pankratz N, Reiner AP, Mathias RA
published in: Cell genomics
information resource reference: Genetic determinants of telomere length from 109,122 ancestrally diverse whole-genome sequences in TOPMed. Cell Genom. 2022 Jan 12; 2(1).
journal title abbreviation: Cell Genom
publication date: 2022-01-12T00:00:00
year: 2022
type: Academic Article
type: Article
type: Document
type: Information Resource

An ancient founder mutation located between ROBO1 and ROBO2 is responsible for increased microtia risk in Amerindigenous populations.
PubMed Identifier: 35584116
author list: Quiat D, Kim SW, Zhang Q, Morton SU, Pereira AC, DePalma SR, Willcox JAL, McDonough B, DeLaughter DM, Gorham JM, Curran JJ, Tumblin M, Nicolau Y, Artunduaga MA, Quintanilla-Dieck L, Osorno G, Serrano L, Hamdan U, Eavey RD, Seidman CE, Seidman JG
published in: Proceedings of the National Academy of Sciences of the United States of America
information resource reference: An ancient founder mutation located between ROBO1 and ROBO2 is responsible for increased microtia risk in Amerindigenous populations. Proc Natl Acad Sci U S A. 2022 05 24; 119(21):e2203928119.
journal title abbreviation: Proc Natl Acad Sci U S A
publication date: 2022-05-18T00:00:00
year: 2022
type: Academic Article
type: Article
type: Document
type: Information Resource

Population Prevalence of Premature Truncating Variants in Plakophilin-2 and Association With Arrhythmogenic Right Ventricular Cardiomyopathy: A UK Biobank Analysis.
PubMed Identifier: 35536239
author list: Hylind RJ, Pereira AC, Quiat D, Chandler SF, Roston TM, Pu WT, Bezzerides VJ, Seidman JG, Seidman CE, Abrams DJ
published in: Circulation. Genomic and precision medicine
information resource reference: Population Prevalence of Premature Truncating Variants in Plakophilin-2 and Association With Arrhythmogenic Right Ventricular Cardiomyopathy: A UK Biobank Analysis. Circ Genom Precis Med. 2022 06; 15(3):e003507.
journal title abbreviation: Circ Genom Precis Med
publication date: 2022-05-10T00:00:00
year: 2022
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 332416
type: Authorship
author rank in publication: 3
linked author: Seidman, Christine
linked information resource: Genetic heterogeneity evidenced by low incidence of KAL-1 gene mutations in sporadic cases of gonadotropin-releasing hormone deficiency.

Ablation of lysophosphatidic acid receptor 1 attenuates hypertrophic cardiomyopathy in a mouse model.
PubMed Identifier: 35787042
author list: Axelsson Raja A, Wakimoto H, DeLaughter DM, Reichart D, Gorham J, Conner DA, Lun M, Probst CK, Sakai N, Knipe RS, Montesi SB, Shea B, Adam LP, Leinwand LA, Wan W, Choi ES, Lindberg EL, Patone G, Noseda M, Hübner N, Seidman CE, Tager AM, Seidman JG, Ho CY
published in: Proceedings of the National Academy of Sciences of the United States of America
information resource reference: Ablation of lysophosphatidic acid receptor 1 attenuates hypertrophic cardiomyopathy in a mouse model. Proc Natl Acad Sci U S A. 2022 07 12; 119(28):e2204174119.
journal title abbreviation: Proc Natl Acad Sci U S A
publication date: 2022-07-05T00:00:00
year: 2022
type: Academic Article
type: Article
type: Document
type: Information Resource

Pathogenic variants damage cell composition and single cell transcription in cardiomyopathies.
PubMed Identifier: 35926050
author list: Reichart D, Lindberg EL, Maatz H, Miranda AMA, Viveiros A, Shvetsov N, Gärtner A, Nadelmann ER, Lee M, Kanemaru K, Ruiz-Orera J, Strohmenger V, DeLaughter DM, Patone G, Zhang H, Woehler A, Lippert C, Kim Y, Adami E, Gorham JM, Barnett SN, Brown K, Buchan RJ, Chowdhury RA, Constantinou C, Cranley J, Felkin LE, Fox H, Ghauri A, Gummert J, Kanda M, Li R, Mach L, McDonough B, Samari S, Shahriaran F, Yapp C, Stanasiuk C, Theotokis PI, Theis FJ, van den Bogaerdt A, Wakimoto H, Ware JS, Worth CL, Barton PJR, Lee YA, Teichmann SA, Milting H, Noseda M, Oudit GY, Heinig M, Seidman JG, Hubner N, Seidman CE
published in: Science (New York, N.Y.)
information resource reference: Pathogenic variants damage cell composition and single cell transcription in cardiomyopathies. Science. 2022 08 05; 377(6606):eabo1984.
journal title abbreviation: Science
publication date: 2022-08-05T00:00:00
year: 2022
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1461009
type: Authorship
author rank in publication: 9
linked author: Seidman, Christine
linked information resource: Myocardial Iron Deficiency and Mitochondrial Dysfunction in Advanced Heart Failure in Humans.

Authorship 1468590
type: Authorship
author rank in publication: 21
linked author: Seidman, Christine
linked information resource: Ablation of lysophosphatidic acid receptor 1 attenuates hypertrophic cardiomyopathy in a mouse model.

Authorship 1466830
type: Authorship
author rank in publication: 8
linked author: Seidman, Christine
linked information resource: Different Transcriptomic Response to T. cruzi Infection in hiPSC-Derived Cardiomyocytes From Chagas Disease Patients With and Without Chronic Cardiomyopathy.

Myocardial Iron Deficiency and Mitochondrial Dysfunction in Advanced Heart Failure in Humans.
PubMed Identifier: 35656974
author list: Zhang H, Jamieson KL, Grenier J, Nikhanj A, Tang Z, Wang F, Wang S, Seidman JG, Seidman CE, Thompson R, Seubert JM, Oudit GY
published in: Journal of the American Heart Association
information resource reference: Myocardial Iron Deficiency and Mitochondrial Dysfunction in Advanced Heart Failure in Humans. J Am Heart Assoc. 2022 06 07; 11(11):e022853.
journal title abbreviation: J Am Heart Assoc
publication date: 2022-06-03T00:00:00
year: 2022
type: Academic Article
type: Article
type: Document
type: Information Resource

Different Transcriptomic Response to T. cruzi Infection in hiPSC-Derived Cardiomyocytes From Chagas Disease Patients With and Without Chronic Cardiomyopathy.
PubMed Identifier: 35873155
author list: Oliveira TGM, Venturini G, Alvim JM, Feijó LL, Dinardo CL, Sabino EC, Seidman JG, Seidman CE, Krieger JE, Pereira AC
published in: Frontiers in cellular and infection microbiology
information resource reference: Different Transcriptomic Response to T. cruzi Infection in hiPSC-Derived Cardiomyocytes From Chagas Disease Patients With and Without Chronic Cardiomyopathy. Front Cell Infect Microbiol. 2022; 12:904747.
journal title abbreviation: Front Cell Infect Microbiol
publication date: 2022-07-07T00:00:00
year: 2022
type: Academic Article
type: Article
type: Document
type: Information Resource

Damaging variants in FOXI3 cause microtia and craniofacial microsomia.
PubMed Identifier: 36260083
author list: Quiat D, Timberlake AT, Curran JJ, Cunningham ML, McDonough B, Artunduaga MA, DePalma SR, Duenas-Roque MM, Gorham JM, Gustafson JA, Hamdan U, Hing AV, Hurtado-Villa P, Nicolau Y, Osorno G, Pachajoa H, Porras-Hurtado GL, Quintanilla-Dieck L, Serrano L, Tumblin M, Zarante I, Luquetti DV, Eavey RD, Heike CL, Seidman JG, Seidman CE
published in: Genetics in medicine : official journal of the American College of Medical Genetics
information resource reference: Damaging variants in FOXI3 cause microtia and craniofacial microsomia. Genet Med. 2023 01; 25(1):143-150.
journal title abbreviation: Genet Med
publication date: 2022-10-19T00:00:00
year: 2022
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1480370
type: Authorship
author rank in publication: 54
linked author: Seidman, Christine
linked information resource: Pathogenic variants damage cell composition and single cell transcription in cardiomyopathies.

Authorship 1484947
type: Authorship
author rank in publication: 7
linked author: Seidman, Christine
linked information resource: Autophagy guided interventions to modify the cardiac phenotype of Danon disease.

Authorship 1502518
type: Authorship
author rank in publication: 14
linked author: Seidman, Christine
linked information resource: Pathogenesis of Cardiomyopathy Caused by Variants in ALPK3, an Essential Pseudokinase in the Cardiomyocyte Nucleus and Sarcomere.

Authorship 1488800
type: Authorship
author rank in publication: 6
linked author: Seidman, Christine
linked information resource: Multiplexed Single-Nucleus RNA Sequencing Using Lipid-Oligo Barcodes.

Authorship 1501976
type: Authorship
author rank in publication: 17
linked author: Seidman, Christine
linked information resource: Genome-wide association study for Chagas Cardiomyopathy identify a new risk locus on chromosome 18 associated with an immune-related protein and transcriptional signature.

Authorship 1490555
type: Authorship
author rank in publication: 26
linked author: Seidman, Christine
linked information resource: Damaging variants in FOXI3 cause microtia and craniofacial microsomia.

Multiplexed Single-Nucleus RNA Sequencing Using Lipid-Oligo Barcodes.
PubMed Identifier: 36286606
author list: Zhang Q, Kim SW, Gorham JM, DeLaughter DM, Ward T, Seidman CE, Seidman JG
published in: Current protocols
information resource reference: Multiplexed Single-Nucleus RNA Sequencing Using Lipid-Oligo Barcodes. Curr Protoc. 2022 Oct; 2(10):e579.
journal title abbreviation: Curr Protoc
publication date: 2022-10-01T00:00:00
year: 2022
type: Academic Article
type: Article
type: Document
type: Information Resource

Genome-wide association study for Chagas Cardiomyopathy identify a new risk locus on chromosome 18 associated with an immune-related protein and transcriptional signature.
PubMed Identifier: 36215317
author list: Sabino EC, Franco LAM, Venturini G, Velho Rodrigues M, Marques E, Oliveira-da Silva LC, Martins LNA, Ferreira AM, Almeida PEC, Silva FDD, Leite SF, Nunes MDCP, Haikal DS, Oliveira CDL, Cardoso CS, Seidman JG, Seidman CE, Casas JP, Ribeiro ALP, Krieger JE, Pereira AC
published in: PLoS neglected tropical diseases
information resource reference: Genome-wide association study for Chagas Cardiomyopathy identify a new risk locus on chromosome 18 associated with an immune-related protein and transcriptional signature. PLoS Negl Trop Dis. 2022 10; 16(10):e0010725.
journal title abbreviation: PLoS Negl Trop Dis
publication date: 2022-10-10T00:00:00
year: 2022
type: Academic Article
type: Article
type: Document
type: Information Resource

Pathogenesis of Cardiomyopathy Caused by Variants in ALPK3, an Essential Pseudokinase in the Cardiomyocyte Nucleus and Sarcomere.
PubMed Identifier: 36321451
author list: Agarwal R, Wakimoto H, Paulo JA, Zhang Q, Reichart D, Toepfer C, Sharma A, Tai AC, Lun M, Gorham J, DePalma SR, Gygi SP, Seidman JG, Seidman CE
published in: Circulation
information resource reference: Pathogenesis of Cardiomyopathy Caused by Variants in ALPK3, an Essential Pseudokinase in the Cardiomyocyte Nucleus and Sarcomere. Circulation. 2022 11 29; 146(22):1674-1693.
journal title abbreviation: Circulation
publication date: 2022-11-02T00:00:00
year: 2022
type: Academic Article
type: Article
type: Document
type: Information Resource

Autophagy guided interventions to modify the cardiac phenotype of Danon disease.
PubMed Identifier: 36027926
author list: Yadin D, Petrover Z, Shainberg A, Alcalai R, Waldman M, Seidman J, Seidman CE, Abraham NG, Hochhauser E, Arad M
published in: Biochemical pharmacology
information resource reference: Autophagy guided interventions to modify the cardiac phenotype of Danon disease. Biochem Pharmacol. 2022 10; 204:115229.
journal title abbreviation: Biochem Pharmacol
publication date: 2022-08-24T00:00:00
year: 2022
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 456083
type: Authorship
author rank in publication: 4
linked author: Seidman, Christine
linked information resource: Sarcomere protein gene mutations and inherited heart disease: a beta-cardiac myosin heavy chain mutation causing endocardial fibroelastosis and heart failure.

Authorship 1512888
type: Authorship
author rank in publication: 9
linked author: Seidman, Christine
linked information resource: Mechanism based therapies enable personalised treatment of hypertrophic cardiomyopathy.

Mechanism based therapies enable personalised treatment of hypertrophic cardiomyopathy.
PubMed Identifier: 36577774
author list: Margara F, Psaras Y, Wang ZJ, Schmid M, Doste R, Garfinkel AC, Repetti GG, Seidman JG, Seidman CE, Rodriguez B, Toepfer CN, Bueno-Orovio A
published in: Scientific reports
information resource reference: Mechanism based therapies enable personalised treatment of hypertrophic cardiomyopathy. Sci Rep. 2022 12 28; 12(1):22501.
journal title abbreviation: Sci Rep
publication date: 2022-12-28T00:00:00
year: 2022
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1517304
type: Authorship
author rank in publication: 50
linked author: Seidman, Christine
linked information resource: Loss of epigenetic information as a cause of mammalian aging.

Loss of epigenetic information as a cause of mammalian aging.
PubMed Identifier: 36638792
author list: Yang JH, Hayano M, Griffin PT, Amorim JA, Bonkowski MS, Apostolides JK, Salfati EL, Blanchette M, Munding EM, Bhakta M, Chew YC, Guo W, Yang X, Maybury-Lewis S, Tian X, Ross JM, Coppotelli G, Meer MV, Rogers-Hammond R, Vera DL, Lu YR, Pippin JW, Creswell ML, Dou Z, Xu C, Mitchell SJ, Das A, O'Connell BL, Thakur S, Kane AE, Su Q, Mohri Y, Nishimura EK, Schaevitz L, Garg N, Balta AM, Rego MA, Gregory-Ksander M, Jakobs TC, Zhong L, Wakimoto H, El Andari J, Grimm D, Mostoslavsky R, Wagers AJ, Tsubota K, Bonasera SJ, Palmeira CM, Seidman JG, Seidman CE, Wolf NS, Kreiling JA, Sedivy JM, Murphy GF, Green RE, Garcia BA, Berger SL, Oberdoerffer P, Shankland SJ, Gladyshev VN, Ksander BR, Pfenning AR, Rajman LA, Sinclair DA
published in: Cell
information resource reference: Loss of epigenetic information as a cause of mammalian aging. Cell. 2023 01 19; 186(2):305-326.e27.
journal title abbreviation: Cell
publication date: 2023-01-12T00:00:00
year: 2023
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1519270
type: Authorship
author rank in publication: 27
linked author: Seidman, Christine
linked information resource: Association of Potentially Damaging De Novo Gene Variants With Neurologic Outcomes in Congenital Heart Disease.

Association of Potentially Damaging De Novo Gene Variants With Neurologic Outcomes in Congenital Heart Disease.
PubMed Identifier: 36701153
author list: Morton SU, Norris-Brilliant A, Cunningham S, King E, Goldmuntz E, Brueckner M, Miller TA, Thomas NH, Liu C, Adams HR, Bellinger DC, Cleveland J, Cnota JF, Dale AM, Frommelt M, Gelb BD, Grant PE, Goldberg CS, Huang H, Kuperman JM, Li JS, McQuillen PS, Panigrahy A, Porter GA, Roberts AE, Russell MW, Seidman CE, Tivarus ME, Anagnoustou E, Hagler DJ, Chung WK, Newburger JW
published in: JAMA network open
information resource reference: Association of Potentially Damaging De Novo Gene Variants With Neurologic Outcomes in Congenital Heart Disease. JAMA Netw Open. 2023 01 03; 6(1):e2253191.
journal title abbreviation: JAMA Netw Open
publication date: 2023-01-03T00:00:00
year: 2023
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1522031
type: Authorship
author rank in publication: 5
linked author: Seidman, Christine
linked information resource: mTOR signaling inhibition decreases lysosome migration and impairs the success of Trypanosoma cruzi infection and replication in cardiomyocytes.

mTOR signaling inhibition decreases lysosome migration and impairs the success of Trypanosoma cruzi infection and replication in cardiomyocytes.
PubMed Identifier: 36709791
author list: Alvim JM, Venturini G, Oliveira TGM, Seidman JG, Seidman CE, Krieger JE, Pereira AC
published in: Acta tropica
information resource reference: mTOR signaling inhibition decreases lysosome migration and impairs the success of Trypanosoma cruzi infection and replication in cardiomyocytes. Acta Trop. 2023 Apr; 240:106845.
journal title abbreviation: Acta Trop
publication date: 2023-01-26T00:00:00
year: 2023
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 241297
type: Authorship
author rank in publication: 12
linked author: Seidman, Christine
linked information resource: An Ryr1I4895T mutation abolishes Ca2+ release channel function and delays development in homozygous offspring of a mutant mouse line.

Authorship 249567
type: Authorship
author rank in publication: 14
linked author: Seidman, Christine
linked information resource: Mutations in human TBX5 [corrected] cause limb and cardiac malformation in Holt-Oram syndrome.

Authorship 1524345
type: Authorship
author rank in publication: 24
linked author: Seidman, Christine
linked information resource: Evidence-Based Assessment of Congenital Heart Disease Genes to Enable Returning Results in a Genomic Study.

Authorship 1524609
type: Authorship
author rank in publication: 15
linked author: Seidman, Christine
linked information resource: Cardiomyocyte infection by Trypanosoma cruzi promotes innate immune response and glycolysis activation.

Authorship 1526571
type: Authorship
author rank in publication: 18
linked author: Seidman, Christine
linked information resource: Efficient in vivo genome editing prevents hypertrophic cardiomyopathy in mice.

Authorship 1523654
type: Authorship
author rank in publication: 61
linked author: Seidman, Christine
linked information resource: Structural variation across 138,134 samples in the TOPMed consortium.

Authorship 1523238
type: Authorship
author rank in publication: 61
linked author: Seidman, Christine
linked information resource: Structural variation across 138,134 samples in the TOPMed consortium.

Structural variation across 138,134 samples in the TOPMed consortium.
PubMed Identifier: 36747810
author list: Jun G, English AC, Metcalf GA, Yang J, Chaisson MJ, Pankratz N, Menon VK, Salerno WJ, Krasheninina O, Smith AV, Lane JA, Blackwell T, Kang HM, Salvi S, Meng Q, Shen H, Pasham D, Bhamidipati S, Kottapalli K, Arnett DK, Ashley-Koch A, Auer PL, Beutel KM, Bis JC, Blangero J, Bowden DW, Brody JA, Cade BE, Chen YI, Cho MH, Curran JE, Fornage M, Freedman BI, Fingerlin T, Gelb BD, Hou L, Hung YJ, Kane JP, Kaplan R, Kim W, Loos RJF, Marcus GM, Mathias RA, McGarvey ST, Montgomery C, Naseri T, Nouraie SM, Preuss MH, Palmer ND, Peyser PA, Raffield LM, Ratan A, Redline S, Reupena S, Rotter JI, Rich SS, Rienstra M, Ruczinski I, Sankaran VG, Schwartz DA, Seidman CE, Seidman JG, Silverman EK, Smith JA, Stilp A, Taylor KD, Telen MJ, Weiss ST, Williams LK, Wu B, Yanek LR, Zhang Y, Lasky-Su J, Gingras MC, Dutcher SK, Eichler EE, Gabriel S, Germer S, Kim R, Viaud-Martinez KA, Nickerson DA, Luo J, Reiner A, Gibbs RA, Boerwinkle E, Abecasis G, Sedlazeck FJ
published in: bioRxiv : the preprint server for biology
information resource reference: Structural variation across 138,134 samples in the TOPMed consortium. bioRxiv. 2023 Jan 25.
journal title abbreviation: bioRxiv
publication date: 2023-01-25T00:00:00
year: 2023
type: Academic Article
type: Article
type: Document
type: Information Resource

Evidence-Based Assessment of Congenital Heart Disease Genes to Enable Returning Results in a Genomic Study.
PubMed Identifier: 36803080
author list: Griffin EL, Nees SN, Morton SU, Wynn J, Patel N, Jobanputra V, Robinson S, Kochav SM, Tao A, Andrews C, Cross N, Geva J, Lanzilotta K, Ritter A, Taillie E, Thompson A, Meyer C, Akers R, King EC, Cnota JF, Kim RW, Porter GA, Brueckner M, Seidman CE, Shen Y, Gelb BD, Goldmuntz E, Newburger JW, Roberts AE, Chung WK
published in: Circulation. Genomic and precision medicine
information resource reference: Evidence-Based Assessment of Congenital Heart Disease Genes to Enable Returning Results in a Genomic Study. Circ Genom Precis Med. 2023 04; 16(2):e003791.
journal title abbreviation: Circ Genom Precis Med
publication date: 2023-02-21T00:00:00
year: 2023
type: Academic Article
type: Article
type: Document
type: Information Resource

Structural variation across 138,134 samples in the TOPMed consortium.
PubMed Identifier: 36778386
author list: Jun G, English AC, Metcalf GA, Yang J, Chaisson MJ, Pankratz N, Menon VK, Salerno WJ, Krasheninina O, Smith AV, Lane JA, Blackwell T, Kang HM, Salvi S, Meng Q, Shen H, Pasham D, Bhamidipati S, Kottapalli K, Arnett DK, Ashley-Koch A, Auer PL, Beutel KM, Bis JC, Blangero J, Bowden DW, Brody JA, Cade BE, Chen YI, Cho MH, Curran JE, Fornage M, Freedman BI, Fingerlin T, Gelb BD, Hou L, Hung YJ, Kane JP, Kaplan R, Kim W, Loos RJF, Marcus GM, Mathias RA, McGarvey ST, Montgomery C, Naseri T, Nouraie SM, Preuss MH, Palmer ND, Peyser PA, Raffield LM, Ratan A, Redline S, Reupena S, Rotter JI, Rich SS, Rienstra M, Ruczinski I, Sankaran VG, Schwartz DA, Seidman CE, Seidman JG, Silverman EK, Smith JA, Stilp A, Taylor KD, Telen MJ, Weiss ST, Williams LK, Wu B, Yanek LR, Zhang Y, Lasky-Su J, Gingras MC, Dutcher SK, Eichler EE, Gabriel S, Germer S, Kim R, Viaud-Martinez KA, Nickerson DA, Luo J, Reiner A, Gibbs RA, Boerwinkle E, Abecasis G, Sedlazeck FJ
published in: Research square
information resource reference: Structural variation across 138,134 samples in the TOPMed consortium. Res Sq. 2023 Feb 03.
journal title abbreviation: Res Sq
publication date: 2023-02-03T00:00:00
year: 2023
type: Academic Article
type: Article
type: Document
type: Information Resource

Cardiomyocyte infection by Trypanosoma cruzi promotes innate immune response and glycolysis activation.
PubMed Identifier: 36814444
author list: Venturini G, Alvim JM, Padilha K, Toepfer CN, Gorham JM, Wasson LK, Biagi D, Schenkman S, Carvalho VM, Salgueiro JS, Cardozo KHM, Krieger JE, Pereira AC, Seidman JG, Seidman CE
published in: Frontiers in cellular and infection microbiology
information resource reference: Cardiomyocyte infection by Trypanosoma cruzi promotes innate immune response and glycolysis activation. Front Cell Infect Microbiol. 2023; 13:1098457.
journal title abbreviation: Front Cell Infect Microbiol
publication date: 2023-02-06T00:00:00
year: 2023
type: Academic Article
type: Article
type: Document
type: Information Resource

Efficient in vivo genome editing prevents hypertrophic cardiomyopathy in mice.
PubMed Identifier: 36797483
author list: Reichart D, Newby GA, Wakimoto H, Lun M, Gorham JM, Curran JJ, Raguram A, DeLaughter DM, Conner DA, Marsiglia JDC, Kohli S, Chmatal L, Page DC, Zabaleta N, Vandenberghe L, Liu DR, Seidman JG, Seidman C
published in: Nature medicine
information resource reference: Efficient in vivo genome editing prevents hypertrophic cardiomyopathy in mice. Nat Med. 2023 02; 29(2):412-421.
journal title abbreviation: Nat Med
publication date: 2023-02-16T00:00:00
year: 2023
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1532375
type: Authorship
author rank in publication: 11
linked author: Seidman, Christine
linked information resource: Multi-Omics Profiling of Hypertrophic Cardiomyopathy Reveals Altered Mechanisms in Mitochondrial Dynamics and Excitation-Contraction Coupling.

Multi-Omics Profiling of Hypertrophic Cardiomyopathy Reveals Altered Mechanisms in Mitochondrial Dynamics and Excitation-Contraction Coupling.
PubMed Identifier: 36902152
author list: Moore J, Ewoldt J, Venturini G, Pereira AC, Padilha K, Lawton M, Lin W, Goel R, Luptak I, Perissi V, Seidman CE, Seidman J, Chin MT, Chen C, Emili A
published in: International journal of molecular sciences
information resource reference: Multi-Omics Profiling of Hypertrophic Cardiomyopathy Reveals Altered Mechanisms in Mitochondrial Dynamics and Excitation-Contraction Coupling. Int J Mol Sci. 2023 Mar 01; 24(5).
journal title abbreviation: Int J Mol Sci
publication date: 2023-03-01T00:00:00
year: 2023
type: Academic Article
type: Article
type: Document
type: Information Resource

Transforming Growth Factor-ß Analysis of the VANISH Trial Cohort.
PubMed Identifier: 36999957
author list: Kim Y, Mastali M, Van Eyk JE, Orav EJ, Vissing CR, Day SM, Axelsson Raja A, Russell MW, Zahka K, Lever HM, Pereira AC, Murphy AM, Canter C, Bach RG, Wheeler MT, Rossano JW, Owens AT, Bundgaard H, Benson L, Mestroni L, Taylor MRG, Patel AR, Wilmot I, Thrush P, Soslow JH, Becker JR, Seidman CE, Ho CY
published in: Circulation. Heart failure
information resource reference: Transforming Growth Factor-ß Analysis of the VANISH Trial Cohort. Circ Heart Fail. 2023 04; 16(4):e010314.
journal title abbreviation: Circ Heart Fail
publication date: 2023-03-31T00:00:00
year: 2023
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 195045
type: Authorship
author rank in publication: 7
linked author: Seidman, Christine
linked information resource: A molecular basis for familial hypertrophic cardiomyopathy: an alpha/beta cardiac myosin heavy chain hybrid gene.

Tbx5 maintains atrial identity by regulating an atrial enhancer network.
PubMed Identifier: 37131696
author list: Sweat ME, Cao Y, Zhang X, Burnicka-Turek O, Perez-Cervantes C, Akerberg BN, Ma Q, Wakimoto H, Gorham JM, Song MK, Trembley MA, Wang P, Lu F, Gianeselli M, Prondzynski M, Bortolin RH, Seidman JG, Seidman CE, Moskowitz IP, Pu WT
published in: bioRxiv : the preprint server for biology
information resource reference: Tbx5 maintains atrial identity by regulating an atrial enhancer network. bioRxiv. 2023 Apr 22.
journal title abbreviation: bioRxiv
publication date: 2023-04-22T00:00:00
year: 2023
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1568373
type: Authorship
author rank in publication: 25
linked author: Seidman, Christine
linked information resource: Contribution of Previously Unrecognized RNA Splice-Altering Variants to Congenital Heart Disease.

Authorship 1560329
type: Authorship
author rank in publication: 27
linked author: Seidman, Christine
linked information resource: Transforming Growth Factor-ß Analysis of the VANISH Trial Cohort.

Authorship 1554719
type: Authorship
author rank in publication: 18
linked author: Seidman, Christine
linked information resource: Tbx5 maintains atrial identity by regulating an atrial enhancer network.

Authorship 1568016
type: Authorship
author rank in publication: 7
linked author: Seidman, Christine
linked information resource: Missense Mutation in Human CHD4 Causes Ventricular Noncompaction by Repressing ADAMTS1.

Authorship 1560026
type: Authorship
author rank in publication: 11
linked author: Seidman, Christine
linked information resource: Oligogenic Architecture of Rare Noncoding Variants Distinguishes 4 Congenital Heart Disease Phenotypes.

Oligogenic Architecture of Rare Noncoding Variants Distinguishes 4 Congenital Heart Disease Phenotypes.
PubMed Identifier: 37026454
author list: Yu M, Aguirre M, Jia M, Gjoni K, Cordova-Palomera A, Munger C, Amgalan D, Rosa Ma X, Pereira A, Tcheandjieu C, Seidman C, Seidman J, Tristani-Firouzi M, Chung W, Goldmuntz E, Srivastava D, Loos RJF, Chami N, Cordell H, Dreßen M, Mueller-Myhsok B, Lahm H, Krane M, Pollard KS, Engreitz JM, Gagliano Taliun SA, Gelb BD, Priest JR
published in: Circulation. Genomic and precision medicine
information resource reference: Oligogenic Architecture of Rare Noncoding Variants Distinguishes 4 Congenital Heart Disease Phenotypes. Circ Genom Precis Med. 2023 06; 16(3):258-266.
journal title abbreviation: Circ Genom Precis Med
publication date: 2023-04-07T00:00:00
year: 2023
type: Academic Article
type: Article
type: Document
type: Information Resource

Missense Mutation in Human CHD4 Causes Ventricular Noncompaction by Repressing ADAMTS1.
PubMed Identifier: 37254794
author list: Shi W, Scialdone AP, Emerson JI, Mei L, Wasson LK, Davies HA, Seidman CE, Seidman JG, Cook JG, Conlon FL
published in: Circulation research
information resource reference: Missense Mutation in Human CHD4 Causes Ventricular Noncompaction by Repressing ADAMTS1. Circ Res. 2023 06 23; 133(1):48-67.
journal title abbreviation: Circ Res
publication date: 2023-05-31T00:00:00
year: 2023
type: Academic Article
type: Article
type: Document
type: Information Resource

Contribution of Previously Unrecognized RNA Splice-Altering Variants to Congenital Heart Disease.
PubMed Identifier: 37165897
author list: Jang MY, Patel PN, Pereira AC, Willcox JAL, Haghighi A, Tai AC, Ito K, Morton SU, Gorham JM, McKean DM, DePalma SR, Bernstein D, Brueckner M, Chung WK, Giardini A, Goldmuntz E, Kaltman JR, Kim R, Newburger JW, Shen Y, Srivastava D, Tristani-Firouzi M, Gelb BD, Porter GA, Seidman CE, Seidman JG
published in: Circulation. Genomic and precision medicine
information resource reference: Contribution of Previously Unrecognized RNA Splice-Altering Variants to Congenital Heart Disease. Circ Genom Precis Med. 2023 06; 16(3):224-231.
journal title abbreviation: Circ Genom Precis Med
publication date: 2023-05-11T00:00:00
year: 2023
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 225084
type: Authorship
author rank in publication: 5
linked author: Seidman, Christine
linked information resource: A dinucleotide repeat polymorphism in the MYBPH gene.

Genetic Contribution to End-Stage Cardiomyopathy Requiring Heart Transplantation.
PubMed Identifier: 37767697
author list: Kim Y, Gunnarsdóttir OB, Viveiros A, Reichart D, Quiat D, Willcox JAL, Zhang H, Chen H, Curran JJ, Kim DH, Urschel S, McDonough B, Gorham J, DePalma SR, Seidman JG, Seidman CE, Oudit GY
published in: Circulation. Genomic and precision medicine
information resource reference: Genetic Contribution to End-Stage Cardiomyopathy Requiring Heart Transplantation. Circ Genom Precis Med. 2023 10; 16(5):452-461.
journal title abbreviation: Circ Genom Precis Med
publication date: 2023-09-28T00:00:00
year: 2023
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1591744
type: Authorship
author rank in publication: 24
linked author: Seidman, Christine
linked information resource: Cardiac Remodeling in Subclinical Hypertrophic Cardiomyopathy: The VANISH Randomized Clinical Trial.

Authorship 1591715
type: Authorship
author rank in publication: 23
linked author: Seidman, Christine
linked information resource: DMD-Associated Dilated Cardiomyopathy: Genotypes, Phenotypes, and Phenocopies.

Authorship 1583863
type: Authorship
author rank in publication: 16
linked author: Seidman, Christine
linked information resource: Genetic Contribution to End-Stage Cardiomyopathy Requiring Heart Transplantation.

Authorship 1584581
type: Authorship
author rank in publication: 6
linked author: Seidman, Christine
linked information resource: Effect of pharmacological heart failure drugs and gene therapy on Danon's cardiomyopathy.

Effect of pharmacological heart failure drugs and gene therapy on Danon's cardiomyopathy.
PubMed Identifier: 37572991
author list: Yadin D, Guetta T, Petrover Z, Alcalai R, Seidman J, Seidman CE, Ofek E, Kornowski R, Hochhauser E, Arad M
published in: Biochemical pharmacology
information resource reference: Effect of pharmacological heart failure drugs and gene therapy on Danon's cardiomyopathy. Biochem Pharmacol. 2023 09; 215:115735.
journal title abbreviation: Biochem Pharmacol
publication date: 2023-08-10T00:00:00
year: 2023
type: Academic Article
type: Article
type: Document
type: Information Resource

DMD-Associated Dilated Cardiomyopathy: Genotypes, Phenotypes, and Phenocopies.
PubMed Identifier: 37671549
author list: Johnson R, Otway R, Chin E, Horvat C, Ohanian M, Wilcox JAL, Su Z, Prestes P, Smolnikov A, Soka M, Guo G, Rath E, Chakravorty S, Chrzanowski L, Hayward CS, Keogh AM, Macdonald PS, Giannoulatou E, Chang ACY, Oates EC, Charchar F, Seidman JG, Seidman CE, Hegde M, Fatkin D
published in: Circulation. Genomic and precision medicine
information resource reference: DMD-Associated Dilated Cardiomyopathy: Genotypes, Phenotypes, and Phenocopies. Circ Genom Precis Med. 2023 10; 16(5):421-430.
journal title abbreviation: Circ Genom Precis Med
publication date: 2023-09-06T00:00:00
year: 2023
type: Academic Article
type: Article
type: Document
type: Information Resource

Cardiac Remodeling in Subclinical Hypertrophic Cardiomyopathy: The VANISH Randomized Clinical Trial.
PubMed Identifier: 37672268
author list: Vissing CR, Axelsson Raja A, Day SM, Russell MW, Zahka K, Lever HM, Pereira AC, Colan SD, Margossian R, Murphy AM, Canter C, Bach RG, Wheeler MT, Rossano JW, Owens AT, Benson L, Mestroni L, Taylor MRG, Patel AR, Wilmot I, Thrush P, Soslow JH, Becker JR, Seidman CE, Lakdawala NK, Cirino AL, McMurray JJV, MacRae CA, Solomon SD, Bundgaard H, Orav EJ, Ho CY
published in: JAMA cardiology
information resource reference: Cardiac Remodeling in Subclinical Hypertrophic Cardiomyopathy: The VANISH Randomized Clinical Trial. JAMA Cardiol. 2023 11 01; 8(11):1083-1088.
journal title abbreviation: JAMA Cardiol
publication date: 2023-11-01T00:00:00
year: 2023
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 428682
type: Authorship
author rank in publication: 12
linked author: Seidman, Christine
linked information resource: A mouse model of congenital heart disease: cardiac arrhythmias and atrial septal defect caused by haploinsufficiency of the cardiac transcription factor Csx/Nkx2.5.

Authorship 447025
type: Authorship
author rank in publication: 2
linked author: Seidman, Christine
linked information resource: Altered crossbridge kinetics in the alphaMHC403/+ mouse model of familial hypertrophic cardiomyopathy.

Authorship 462768
type: Authorship
author rank in publication: 7
linked author: Seidman, Christine
linked information resource: Filter-based hybridization capture of subgenomes enables resequencing and copy-number detection.

Authorship 184325
type: Authorship
author rank in publication: 6
linked author: Seidman, Christine
linked information resource: https://connects.catalyst.harvard.edu/Profiles/profile/818427

Authorship 1608722
type: Authorship
author rank in publication: 7
linked author: Seidman, Christine
linked information resource: The H2Bub1-deposition complex is required for human and mouse cardiogenesis.

The H2Bub1-deposition complex is required for human and mouse cardiogenesis.
PubMed Identifier: 38038666
author list: Barish S, Berg K, Drozd J, Berglund-Brown I, Khizir L, Wasson LK, Seidman CE, Seidman JG, Chen S, Brueckner M
published in: Development (Cambridge, England)
information resource reference: The H2Bub1-deposition complex is required for human and mouse cardiogenesis. Development. 2023 12 01; 150(23).
journal title abbreviation: Development
publication date: 2023-12-01T00:00:00
year: 2023
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 519202
type: Authorship
author rank in publication: 6
linked author: Seidman, Christine
linked information resource: Characteristics and prognostic implications of myosin missense mutations in familial hypertrophic cardiomyopathy.

Authorship 547698
type: Authorship
author rank in publication: 7
linked author: Seidman, Christine
linked information resource: Effects of two familial hypertrophic cardiomyopathy-causing mutations on alpha-tropomyosin structure and function

Authorship 569307
type: Authorship
author rank in publication: 2
linked author: Seidman, Christine
linked information resource: The Good SHP2 Association: a porthole into the genetics of congenital heart disease.

Professor of Medicine
is primary position: true
position in department: Medicine
position in division: Cardiology
sort order: 1
type: Position
HR job title: Professor of Medicine
position in organization: Brigham and Women's Hospital

Authorship 1627515
type: Authorship
author rank in publication: 12
linked author: Seidman, Christine
linked information resource: Direct reprogramming of non-limb fibroblasts to cells with properties of limb progenitors.

Direct reprogramming of non-limb fibroblasts to cells with properties of limb progenitors.
PubMed Identifier: 38320485
author list: Atsuta Y, Lee C, Rodrigues AR, Colle C, Tomizawa RR, Lujan EG, Tschopp P, Galan L, Zhu M, Gorham JM, Vannier JP, Seidman CE, Seidman JG, Ros MA, Pourquié O, Tabin CJ
published in: Developmental cell
information resource reference: Direct reprogramming of non-limb fibroblasts to cells with properties of limb progenitors. Dev Cell. 2024 02 05; 59(3):415-430.e8.
journal title abbreviation: Dev Cell
publication date: 2024-02-05T00:00:00
year: 2024
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 17749
type: Authorship
author rank in publication: 4
linked author: Seidman, Christine
linked information resource: Natriuretic peptide system gene variants are associated with ventricular dysfunction after coronary artery bypass grafting.

Authorship 218872
type: Authorship
author rank in publication: 5
linked author: Seidman, Christine
linked information resource: Neonatal atria and ventricles secrete atrial natriuretic factor via tissue-specific secretory pathways.

Authorship 1630836
type: Authorship
author rank in publication: 23
linked author: Seidman, Christine
linked information resource: Tbx5 maintains atrial identity in post-natal cardiomyocytes by regulating an atrial-specific enhancer network.

Authorship 1632762
type: Authorship
author rank in publication: 20
linked author: Seidman, Christine
linked information resource: Functional dissection of human cardiac enhancers and noncoding de novo variants in congenital heart disease.

Authorship 1629101
type: Authorship
author rank in publication: 50
linked author: Seidman, Christine
linked information resource: Loss of epigenetic information as a cause of mammalian aging.

Authorship 1631053
type: Authorship
author rank in publication: 9
linked author: Seidman, Christine
linked information resource: Molecular and Spatial Signatures of Mouse Embryonic Endothelial Cells at Single-Cell Resolution.

Molecular and Spatial Signatures of Mouse Embryonic Endothelial Cells at Single-Cell Resolution.
PubMed Identifier: 38348657
author list: Chen J, Zhang X, DeLaughter DM, Trembley MA, Saifee S, Xiao F, Chen J, Zhou P, Seidman CE, Seidman JG, Pu WT
published in: Circulation research
information resource reference: Molecular and Spatial Signatures of Mouse Embryonic Endothelial Cells at Single-Cell Resolution. Circ Res. 2024 03; 134(5):529-546.
journal title abbreviation: Circ Res
publication date: 2024-02-13T00:00:00
year: 2024
type: Academic Article
type: Article
type: Document
type: Information Resource

Functional dissection of human cardiac enhancers and noncoding de novo variants in congenital heart disease.
PubMed Identifier: 38378865
author list: Xiao F, Zhang X, Morton SU, Kim SW, Fan Y, Gorham JM, Zhang H, Berkson PJ, Mazumdar N, Cao Y, Chen J, Hagen J, Liu X, Zhou P, Richter F, Shen Y, Ward T, Gelb BD, Seidman JG, Seidman CE, Pu WT
published in: Nature genetics
information resource reference: Functional dissection of human cardiac enhancers and noncoding de novo variants in congenital heart disease. Nat Genet. 2024 Mar; 56(3):420-430.
journal title abbreviation: Nat Genet
publication date: 2024-02-20T00:00:00
year: 2024
type: Academic Article
type: Article
type: Document
type: Information Resource

Tbx5 maintains atrial identity in post-natal cardiomyocytes by regulating an atrial-specific enhancer network.
PubMed Identifier: 38344303
author list: Sweat ME, Cao Y, Zhang X, Burnicka-Turek O, Perez-Cervantes C, Arulsamy K, Lu F, Keating EM, Akerberg BN, Ma Q, Wakimoto H, Gorham JM, Hill LD, Kyoung Song M, Trembley MA, Wang P, Gianeselli M, Prondzynski M, Bortolin RH, Bezzerides VJ, Chen K, Seidman JG, Seidman CE, Moskowitz IP, Pu WT
published in: Nature cardiovascular research
information resource reference: Tbx5 maintains atrial identity in post-natal cardiomyocytes by regulating an atrial-specific enhancer network. Nat Cardiovasc Res. 2023 Oct; 2(10):881-898.
journal title abbreviation: Nat Cardiovasc Res
publication date: 2023-10-12T00:00:00
year: 2023
type: Academic Article
type: Article
type: Document
type: Information Resource

Loss of epigenetic information as a cause of mammalian aging.
PubMed Identifier: 38428398
author list: Yang JH, Hayano M, Griffin PT, Amorim JA, Bonkowski MS, Apostolides JK, Salfati EL, Blanchette M, Munding EM, Bhakta M, Chew YC, Guo W, Yang X, Maybury-Lewis S, Tian X, Ross JM, Coppotelli G, Meer MV, Rogers-Hammond R, Vera DL, Lu YR, Pippin JW, Creswell ML, Dou Z, Xu C, Mitchell SJ, Das A, O'Connell BL, Thakur S, Kane AE, Su Q, Mohri Y, Nishimura EK, Schaevitz L, Garg N, Balta AM, Rego MA, Gregory-Ksander M, Jakobs TC, Zhong L, Wakimoto H, El Andari J, Grimm D, Mostoslavsky R, Wagers AJ, Tsubota K, Bonasera SJ, Palmeira CM, Seidman JG, Seidman CE, Wolf NS, Kreiling JA, Sedivy JM, Murphy GF, Green RE, Garcia BA, Berger SL, Oberdoerffer P, Shankland SJ, Gladyshev VN, Ksander BR, Pfenning AR, Rajman LA, Sinclair DA
published in: Cell
information resource reference: Loss of epigenetic information as a cause of mammalian aging. Cell. 2024 Feb 29; 187(5):1312-1313.
journal title abbreviation: Cell
publication date: 2024-02-29T00:00:00
year: 2024
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 553825
type: Authorship
author rank in publication: 2
linked author: Seidman, Christine
linked information resource: Many roads lead to a broken heart: the genetics of dilated cardiomyopathy.

Authorship 1638414
type: Authorship
author rank in publication: 20
linked author: Seidman, Christine
linked information resource: The BMAL1/HIF2A heterodimer modulates circadian variations of myocardial injury.

The BMAL1/HIF2A heterodimer modulates circadian variations of myocardial injury.
PubMed Identifier: 38464103
author list: Ruan W, Li T, Lee J, Bang IH, Deng W, Ma X, Yoo SH, Kim B, Li J, Yuan X, An YA, Wang YY, Liang Y, Deberge M, Zhang D, Zhou Z, Wang Y, Gorham J, Seidman JG, Seidman CE, Aranki SF, Nair R, Li L, Narula J, Zhao Z, Abebe AG, Muehlschlegel JD, Tsai KL, Eltzschig HK
published in: Research square
information resource reference: The BMAL1/HIF2A heterodimer modulates circadian variations of myocardial injury. Res Sq. 2024 Feb 28.
journal title abbreviation: Res Sq
publication date: 2024-02-28T00:00:00
year: 2024
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1641625
type: Authorship
author rank in publication: 11
linked author: Seidman, Christine
linked information resource: Automated Identification of Germline de novo Mutations in Family Trios: A Consensus-Based Informatic Approach.

Authorship 1641611
type: Authorship
author rank in publication: 17
linked author: Seidman, Christine
linked information resource: An engineered human cardiac tissue model reveals contributions of systemic lupus erythematosus autoantibodies to myocardial injury.

An engineered human cardiac tissue model reveals contributions of systemic lupus erythematosus autoantibodies to myocardial injury.
PubMed Identifier: 38559188
author list: Fleischer S, Nash TR, Tamargo MA, Lock RI, Venturini G, Morsink M, Li V, Lamberti MJ, Graney PL, Liberman M, Kim Y, Zhuang RZ, Whitehead J, Friedman RA, Soni RK, Seidman JG, Seidman CE, Geraldino-Pardilla L, Winchester R, Vunjak-Novakovic G
published in: bioRxiv : the preprint server for biology
information resource reference: An engineered human cardiac tissue model reveals contributions of systemic lupus erythematosus autoantibodies to myocardial injury. bioRxiv. 2024 Mar 12.
journal title abbreviation: bioRxiv
publication date: 2024-03-12T00:00:00
year: 2024
type: Academic Article
type: Article
type: Document
type: Information Resource

Automated Identification of Germline de novo Mutations in Family Trios: A Consensus-Based Informatic Approach.
PubMed Identifier: 38559260
author list: Shadrina M, Kalay Ö, Demirkaya-Budak S, LeDuc CA, Chung WK, Turgut D, Budak G, Arslan E, Semenyuk V, Davis-Dusenbery B, Seidman CE, Yost HJ, Jain A, Gelb BD
published in: bioRxiv : the preprint server for biology
information resource reference: Automated Identification of Germline de novo Mutations in Family Trios: A Consensus-Based Informatic Approach. bioRxiv. 2024 Mar 13.
journal title abbreviation: bioRxiv
publication date: 2024-03-13T00:00:00
year: 2024
type: Academic Article
type: Article
type: Document
type: Information Resource

Identifying unrecognized genetic causes of congenital heart disease
end date: 2028-03-31
principal investigator name: SEIDMAN, CHRISTINE E
start date: 2024-06-01
type: Grant
sponsor award id: R01HL162356

Principal Investigator
type: Researcher Role
researcher role of: Seidman, Christine
contributes to: Identifying unrecognized genetic causes of congenital heart disease

Authorship 1651110
type: Authorship
author rank in publication: 8
linked author: Seidman, Christine
linked information resource: CHD4 and SMYD1 repress common transcriptional programs in the developing heart.

Authorship 1652909
type: Authorship
author rank in publication: 20
linked author: Seidman, Christine
linked information resource: Genome Sequencing is Critical for Forecasting Outcomes Following Congenital Cardiac Surgery.

Genome Sequencing is Critical for Forecasting Outcomes Following Congenital Cardiac Surgery.
PubMed Identifier: 38746151
author list: Watkins WS, Hernandez EJ, Miller T, Blue N, Zimmerman R, Griffiths E, Frise E, Bernstein D, Boskovski M, Brueckner M, Chung W, Gaynor JW, Gelb B, Goldmuntz E, Gruber P, Newburger J, Roberts A, Morton S, Mayer J, Seidman C, Seidman J, Shen Y, Wagner M, Yost HJ, Yandell M, Tristani-Firouzi M
published in: medRxiv : the preprint server for health sciences
information resource reference: Genome Sequencing is Critical for Forecasting Outcomes Following Congenital Cardiac Surgery. medRxiv. 2024 Nov 15.
journal title abbreviation: medRxiv
publication date: 2024-11-15T00:00:00
year: 2024
type: Academic Article
type: Article
type: Document
type: Information Resource

CHD4 and SMYD1 repress common transcriptional programs in the developing heart.
PubMed Identifier: 38619323
author list: Shi W, Wasson LK, Dorr KM, Robbe ZL, Wilczewski CM, Hepperla AJ, Davis IJ, Seidman CE, Seidman JG, Conlon FL
published in: Development (Cambridge, England)
information resource reference: CHD4 and SMYD1 repress common transcriptional programs in the developing heart. Development. 2024 Apr 15; 151(8).
journal title abbreviation: Development
publication date: 2024-04-15T00:00:00
year: 2024
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1656796
type: Authorship
author rank in publication: 24
linked author: Seidman, Christine
linked information resource: Increased endothelial sclerostin caused by elevated DSCAM mediates multiple trisomy 21 phenotypes.

Increased endothelial sclerostin caused by elevated DSCAM mediates multiple trisomy 21 phenotypes.
PubMed Identifier: 38828726
author list: McKean DM, Zhang Q, Narayan P, Morton SU, Strohmenger V, Tang VT, McAllister S, Sharma A, Quiat D, Reichart D, DeLaughter DM, Wakimoto H, Gorham JM, Brown K, McDonough B, Willcox JA, Jang MY, DePalma SR, Ward T, Kim R, Cleveland JD, Seidman JG, Seidman CE
published in: The Journal of clinical investigation
information resource reference: Increased endothelial sclerostin caused by elevated DSCAM mediates multiple trisomy 21 phenotypes. J Clin Invest. 2024 Jun 03; 134(11).
journal title abbreviation: J Clin Invest
publication date: 2024-06-03T00:00:00
year: 2024
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 309911
type: Authorship
author rank in publication: 7
linked author: Seidman, Christine
linked information resource: IL-12 is required for differentiation of pathogenic CD8+ T cell effectors that cause myocarditis.

Authorship 1664522
type: Authorship
author rank in publication: 23
linked author: Seidman, Christine
linked information resource: Identifying novel data-driven subgroups in congenital heart disease using multi-modal measures of brain structure.

Identifying novel data-driven subgroups in congenital heart disease using multi-modal measures of brain structure.
PubMed Identifier: 38968977
author list: Vandewouw MM, Norris-Brilliant A, Rahman A, Assimopoulos S, Morton SU, Kushki A, Cunningham S, King E, Goldmuntz E, Miller TA, Thomas NH, Adams HR, Cleveland J, Cnota JF, Ellen Grant P, Goldberg CS, Huang H, Li JS, McQuillen P, Porter GA, Roberts AE, Russell MW, Seidman CE, Tivarus ME, Chung WK, Hagler DJ, Newburger JW, Panigrahy A, Lerch JP, Gelb BD, Anagnostou E
published in: NeuroImage
information resource reference: Identifying novel data-driven subgroups in congenital heart disease using multi-modal measures of brain structure. Neuroimage. 2024 Aug 15; 297:120721.
journal title abbreviation: Neuroimage
publication date: 2024-07-04T00:00:00
year: 2024
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1665046
type: Authorship
author rank in publication: 7
linked author: Seidman, Christine
linked information resource: Genetic therapies for cardiomyopathy: survey of attitudes of the patient community for the CureHeart project.

Genetic therapies for cardiomyopathy: survey of attitudes of the patient community for the CureHeart project.
PubMed Identifier: 38972962
author list: Ormondroyd E, Grace C, Borsari W, Goel A, McDonough B, Rose J, Seidman C, Watkins H
published in: European journal of human genetics : EJHG
information resource reference: Genetic therapies for cardiomyopathy: survey of attitudes of the patient community for the CureHeart project. Eur J Hum Genet. 2024 Sep; 32(9):1045-1052.
journal title abbreviation: Eur J Hum Genet
publication date: 2024-07-07T00:00:00
year: 2024
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 390430
type: Authorship
author rank in publication: 2
linked author: Seidman, Christine
linked information resource: Genetics of cardiovascular disease.

Authorship 244852
type: Authorship
author rank in publication: 15
linked author: Seidman, Christine
linked information resource: Dilated cardiomyopathy in homozygous myosin-binding protein-C mutant mice.

Assistant Professor of Medicine
is primary position: true
position in department: Medicine
position in division: Cardiology
sort order: 1
type: Position
HR job title: Assistant Professor of Medicine
position in organization: Brigham and Women's Hospital

Professor of Medicine
is primary position: true
position in department: Medicine
position in division: Cardiology
sort order: 1
type: Position
HR job title: Professor of Medicine
position in organization: Brigham and Women's Hospital

Assistant Professor of Medicine
is primary position: true
position in department: Medicine
position in division: Cardiology
sort order: 1
type: Position
HR job title: Assistant Professor of Medicine
position in organization: Brigham and Women's Hospital

Professor of Genetics
position in department: Genetics
position in division: https://connects.catalyst.harvard.edu/Profiles/profile/1229413
sort order: 2
type: Position
HR job title: Professor of Genetics
position in organization: Harvard Medical School

Henrietta B. and Frederick H. Bugher Foundation Professor of Genetics
is primary position: true
position in department: Genetics
position in division: https://connects.catalyst.harvard.edu/Profiles/profile/1229413
sort order: 1
type: Position
HR job title: Henrietta B. and Frederick H. Bugher Foundation Professor of Genetics
position in organization: Harvard Medical School

Thomas W. Smith Professor of Medicine
is primary position: true
position in department: Medicine
position in division: Cardiology
sort order: 1
type: Position
HR job title: Thomas W. Smith Professor of Medicine
position in organization: Brigham and Women's Hospital

Authorship 437495
type: Authorship
author rank in publication: 12
linked author: Seidman, Christine
linked information resource: Clinical outcome and phenotypic expression in LAMP2 cardiomyopathy.

Authorship 479171
type: Authorship
author rank in publication: 8
linked author: Seidman, Christine
linked information resource: Alterations of phospholamban function can exhibit cardiotoxic effects independent of excessive sarcoplasmic reticulum Ca2+-ATPase inhibition.

Authorship 245239
type: Authorship
author rank in publication: 16
linked author: Seidman, Christine
linked information resource: Comparison of two murine models of familial hypertrophic cardiomyopathy.

Authorship 247015
type: Authorship
author rank in publication: 11
linked author: Seidman, Christine
linked information resource: Reversibility of PRKAG2 glycogen-storage cardiomyopathy and electrophysiological manifestations.

Authorship 290549
type: Authorship
author rank in publication: 5
linked author: Seidman, Christine
linked information resource: Genomewide linkage in a large Caucasian family maps a new locus for intracranial aneurysms to chromosome 13q.

Authorship 30300
type: Authorship
author rank in publication: 15
linked author: Seidman, Christine
linked information resource: Dilated cardiomyopathy in homozygous myosin-binding protein-C mutant mice

Authorship 1684745
type: Authorship
author rank in publication: 23
linked author: Seidman, Christine
linked information resource: Author Correction: Tbx5 maintains atrial identity in postnatal cardiomyocytes by regulating an atrial-specific enhancer network.

Authorship 1684723
type: Authorship
author rank in publication: 18
linked author: Seidman, Christine
linked information resource: An engineered human cardiac tissue model reveals contributions of systemic lupus erythematosus autoantibodies to myocardial injury.

Authorship 1685210
type: Authorship
author rank in publication: 5
linked author: Seidman, Christine
linked information resource: Predictive modeling of endocardial fibroelastosis recurrence in patients with congenital heart disease.

Authorship 1685378
type: Authorship
author rank in publication: 8
linked author: Seidman, Christine
linked information resource: Engineered human iPS cell models reveal altered podocytogenesis and glomerular capillary wall in CHD-associated SMAD2 mutations.

Author Correction: Tbx5 maintains atrial identity in postnatal cardiomyocytes by regulating an atrial-specific enhancer network.
PubMed Identifier: 39196102
author list: Sweat ME, Cao Y, Zhang X, Burnicka-Turek O, Perez-Cervantes C, Kulandaisamy A, Lu F, Keating EM, Akerberg BN, Ma Q, Wakimoto H, Gorham JM, Hill LD, Song MK, Trembley MA, Wang P, Gianeselli M, Prondzynski M, Bortolin RH, Bezzerides VJ, Chen K, Seidman JG, Seidman CE, Moskowitz IP, Pu WT
published in: Nature cardiovascular research
information resource reference: Author Correction: Tbx5 maintains atrial identity in postnatal cardiomyocytes by regulating an atrial-specific enhancer network. Nat Cardiovasc Res. 2023 Nov; 2(11):1095.
journal title abbreviation: Nat Cardiovasc Res
publication date: 2023-11-01T00:00:00
year: 2023
type: Academic Article
type: Article
type: Document
type: Information Resource

An engineered human cardiac tissue model reveals contributions of systemic lupus erythematosus autoantibodies to myocardial injury.
PubMed Identifier: 39195859
author list: Fleischer S, Nash TR, Tamargo MA, Lock RI, Venturini G, Morsink M, Graney PL, Li V, Lamberti MJ, Liberman M, Kim Y, Tavakol DN, Zhuang RZ, Whitehead J, Friedman RA, Soni RK, Seidman JG, Seidman CE, Geraldino-Pardilla L, Winchester R, Vunjak-Novakovic G
published in: Nature cardiovascular research
information resource reference: An engineered human cardiac tissue model reveals contributions of systemic lupus erythematosus autoantibodies to myocardial injury. Nat Cardiovasc Res. 2024 Sep; 3(9):1123-1139.
journal title abbreviation: Nat Cardiovasc Res
publication date: 2024-08-15T00:00:00
year: 2024
type: Academic Article
type: Article
type: Document
type: Information Resource

Engineered human iPS cell models reveal altered podocytogenesis and glomerular capillary wall in CHD-associated SMAD2 mutations.
PubMed Identifier: 39211233
author list: Bhattacharya R, Ward T, Kalejaiye TD, Mishra A, Leeman S, Arzaghi H, Seidman JG, Seidman CE, Musah S
published in: bioRxiv : the preprint server for biology
information resource reference: Engineered human iPS cell models reveal altered podocytogenesis and glomerular capillary wall in CHD-associated SMAD2 mutations. bioRxiv. 2024 Aug 06.
journal title abbreviation: bioRxiv
publication date: 2024-08-06T00:00:00
year: 2024
type: Academic Article
type: Article
type: Document
type: Information Resource

Predictive modeling of endocardial fibroelastosis recurrence in patients with congenital heart disease.
PubMed Identifier: 39208926
author list: Diaz-Gil D, Silva-Gomez N, Morton SU, Seidman JG, Seidman CE, Zurakowski D, Staffa SJ, Marx GR, Emani SM, Del Nido PJ, Friehs I
published in: The Journal of thoracic and cardiovascular surgery
information resource reference: Predictive modeling of endocardial fibroelastosis recurrence in patients with congenital heart disease. J Thorac Cardiovasc Surg. 2025 02; 169(2):366-374.
journal title abbreviation: J Thorac Cardiovasc Surg
publication date: 2024-08-27T00:00:00
year: 2024
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 489939
type: Authorship
author rank in publication: 1
linked author: Seidman, Christine
linked information resource: The structure of rat preproatrial natriuretic factor as defined by a complementary DNA clone.

Authorship 647685
type: Authorship
author rank in publication: 49
linked author: Seidman, Christine
linked information resource: De novo mutations in histone-modifying genes in congenital heart disease.

Authorship 664802
type: Authorship
author rank in publication: 4
linked author: Seidman, Christine
linked information resource: Spatial transcriptional profile of the chick and mouse endocardial cushions identify novel regulators of endocardial EMT in vitro.

Authorship 658582
type: Authorship
author rank in publication: 20
linked author: Seidman, Christine
linked information resource: Functional characterization of a novel mutation in NKX2-5 associated with congenital heart disease and adult-onset cardiomyopathy.

Spatial transcriptional profile of the chick and mouse endocardial cushions identify novel regulators of endocardial EMT in vitro.
PubMed Identifier: 23557753
author list: DeLaughter DM, Christodoulou DC, Robinson JY, Seidman CE, Baldwin HS, Seidman JG, Barnett JV
published in: Journal of molecular and cellular cardiology
information resource reference: Spatial transcriptional profile of the chick and mouse endocardial cushions identify novel regulators of endocardial EMT in vitro. J Mol Cell Cardiol. 2013 Jun; 59:196-204.
journal title abbreviation: J Mol Cell Cardiol
publication date: 2013-04-01T00:00:00
year: 2013
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 362743
type: Authorship
author rank in publication: 8
linked author: Seidman, Christine
linked information resource: Familial hypertrophic cardiomyopathy is a genetically heterogeneous disease.

Functional characterization of a novel mutation in NKX2-5 associated with congenital heart disease and adult-onset cardiomyopathy.
PubMed Identifier: 23661673
author list: Costa MW, Guo G, Wolstein O, Vale M, Castro ML, Wang L, Otway R, Riek P, Cochrane N, Furtado M, Semsarian C, Weintraub RG, Yeoh T, Hayward C, Keogh A, Macdonald P, Feneley M, Graham RM, Seidman JG, Seidman CE, Rosenthal N, Fatkin D, Harvey RP
published in: Circulation. Cardiovascular genetics
information resource reference: Functional characterization of a novel mutation in NKX2-5 associated with congenital heart disease and adult-onset cardiomyopathy. Circ Cardiovasc Genet. 2013 Jun; 6(3):238-47.
journal title abbreviation: Circ Cardiovasc Genet
publication date: 2013-05-09T00:00:00
year: 2013
type: Academic Article
type: Article
type: Document
type: Information Resource

De novo mutations in histone-modifying genes in congenital heart disease.
PubMed Identifier: 23665959
author list: Zaidi S, Choi M, Wakimoto H, Ma L, Jiang J, Overton JD, Romano-Adesman A, Bjornson RD, Breitbart RE, Brown KK, Carriero NJ, Cheung YH, Deanfield J, DePalma S, Fakhro KA, Glessner J, Hakonarson H, Italia MJ, Kaltman JR, Kaski J, Kim R, Kline JK, Lee T, Leipzig J, Lopez A, Mane SM, Mitchell LE, Newburger JW, Parfenov M, Pe'er I, Porter G, Roberts AE, Sachidanandam R, Sanders SJ, Seiden HS, State MW, Subramanian S, Tikhonova IR, Wang W, Warburton D, White PS, Williams IA, Zhao H, Seidman JG, Brueckner M, Chung WK, Gelb BD, Goldmuntz E, Seidman CE, Lifton RP
published in: Nature
information resource reference: De novo mutations in histone-modifying genes in congenital heart disease. Nature. 2013 Jun 13; 498(7453):220-3.
journal title abbreviation: Nature
publication date: 2013-05-12T00:00:00
year: 2013
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1701632
type: Authorship
author rank in publication: 16
linked author: Seidman, Christine
linked information resource: Hypertrophic cardiomyopathy-associated mutations drive stromal activation via EGFR-mediated paracrine signaling.

Hypertrophic cardiomyopathy-associated mutations drive stromal activation via EGFR-mediated paracrine signaling.
PubMed Identifier: 39413182
author list: Ewoldt JK, Wang MC, McLellan MA, Cloonan PE, Chopra A, Gorham J, Li L, DeLaughter DM, Gao X, Lee JH, Willcox JAL, Layton O, Luu RJ, Toepfer CN, Eyckmans J, Seidman CE, Seidman JG, Chen CS
published in: Science advances
information resource reference: Hypertrophic cardiomyopathy-associated mutations drive stromal activation via EGFR-mediated paracrine signaling. Sci Adv. 2024 10 18; 10(42):eadi6927.
journal title abbreviation: Sci Adv
publication date: 2024-10-16T00:00:00
year: 2024
type: Academic Article
type: Article
type: Document
type: Information Resource

Professor of Medicine
is primary position: true
position in department: Medicine
position in division: Cardiology
sort order: 1
type: Position
HR job title: Professor of Medicine
position in organization: Brigham and Women's Hospital

Gene Therapy in Cardiovascular Disease: Recent Advances and Future Directions in Science: A Science Advisory From the American Heart Association.
PubMed Identifier: 39523949
author list: Kim Y, Landstrom AP, Shah SH, Wu JC, Seidman CE
published in: Circulation
information resource reference: Gene Therapy in Cardiovascular Disease: Recent Advances and Future Directions in Science: A Science Advisory From the American Heart Association. Circulation. 2024 Dec 03; 150(23):e471-e480.
journal title abbreviation: Circulation
publication date: 2024-11-11T00:00:00
year: 2024
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1706731
type: Authorship
author rank in publication: 5
linked author: Seidman, Christine
linked information resource: Gene Therapy in Cardiovascular Disease: Recent Advances and Future Directions in Science: A Science Advisory From the American Heart Association.

Authorship 1709561
type: Authorship
author rank in publication: 14
linked author: Seidman, Christine
linked information resource: Genomic rare variant mechanisms for congenital cardiac laterality defect: A digenic model approach.

Genomic rare variant mechanisms for congenital cardiac laterality defect: A digenic model approach.
PubMed Identifier: 39606420
author list: Rai A, Klonowski J, Yuan B, Coveler KJ, Dardas Z, Egab I, Xu J, Lupo PJ, Agopian AJ, Kostka D, Lo CW, Yi SS, Gelb BD, Seidman CE, Boerwinkle E, Posey JE, Gibbs RA, Lupski JR, Morris SA, Coban-Akdemir Z
published in: medRxiv : the preprint server for health sciences
information resource reference: Genomic rare variant mechanisms for congenital cardiac laterality defect: A digenic model approach. medRxiv. 2024 Nov 21.
journal title abbreviation: medRxiv
publication date: 2024-11-21T00:00:00
year: 2024
type: Academic Article
type: Article
type: Document
type: Information Resource

Regulation of sarcomere formation and function in the healthy heart requires a titin intronic enhancer.
PubMed Identifier: 39688912
author list: Kim Y, Kim SW, Saul D, Neyazi M, Schmid M, Wakimoto H, Slaven N, Lee JH, Layton O, Wasson LK, Letendre JH, Xiao F, Ewoldt JK, Gkatzis K, Sommer P, Gobert B, Wiest-Daesslé N, McAfee Q, Singhal N, Lun M, Gorham JM, Arany Z, Sharma A, Toepfer CN, Oudit GY, Pu WT, Dickel DE, Pennacchio LA, Visel A, Chen CS, Seidman JG, Seidman CE
published in: The Journal of clinical investigation
information resource reference: Regulation of sarcomere formation and function in the healthy heart requires a titin intronic enhancer. J Clin Invest. 2024 Dec 17; 135(4).
journal title abbreviation: J Clin Invest
publication date: 2024-12-17T00:00:00
year: 2024
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 516433
type: Authorship
author rank in publication: 2
linked author: Seidman, Christine
linked information resource: Atrial natriuretic factor and related peptide hormones.

Authorship 539742
type: Authorship
author rank in publication: 4
linked author: Seidman, Christine
linked information resource: Genetics of congenital heart disease: the glass half empty.

Cardiac fibroblast BAG3 regulates TGFBR2 signaling and fibrosis in dilated cardiomyopathy.
PubMed Identifier: 39744939
author list: Wang BZ, Morsink MA, Kim SW, Luo LJ, Zhang X, Soni RK, Lock RI, Rao J, Kim Y, Zhang A, Neyazi M, Gorham JM, Kim Y, Brown K, DeLaughter DM, Zhang Q, McDonough B, Watkins JM, Cunningham KM, Oudit GY, Fine BM, Seidman CE, Seidman JG, Vunjak-Novakovic G
published in: The Journal of clinical investigation
information resource reference: Cardiac fibroblast BAG3 regulates TGFBR2 signaling and fibrosis in dilated cardiomyopathy. J Clin Invest. 2025 Jan 02; 135(1).
journal title abbreviation: J Clin Invest
publication date: 2025-01-02T00:00:00
year: 2025
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 188190
type: Authorship
author rank in publication: 6
linked author: Seidman, Christine
linked information resource: Identification of genetic loci associated with paralysis, inflammation and weight loss in mouse experimental autoimmune encephalomyelitis.

Authorship 189064
type: Authorship
author rank in publication: 41
linked author: Seidman, Christine
linked information resource: A public resource facilitating clinical use of genomes.

Genetic diagnosis of facioscapulohumeral muscular dystrophy type 1 using rare-variant linkage analysis and long-read genome sequencing.
PubMed Identifier: 39669606
author list: Li K, Quiat D, She F, Liu Y, He R, Haghighi A, Liu F, Zhang R, DePalma SR, Yang Y, Wang W, Seidman CE, Zhang P, Seidman JG
published in: Genetics in medicine open
information resource reference: Genetic diagnosis of facioscapulohumeral muscular dystrophy type 1 using rare-variant linkage analysis and long-read genome sequencing. Genet Med Open. 2024; 2:101817.
journal title abbreviation: Genet Med Open
publication date: 2024-01-29T00:00:00
year: 2024
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1720444
type: Authorship
author rank in publication: 32
linked author: Seidman, Christine
linked information resource: Regulation of sarcomere formation and function in the healthy heart requires a titin intronic enhancer.

Authorship 1717043
type: Authorship
author rank in publication: 22
linked author: Seidman, Christine
linked information resource: Cardiac fibroblast BAG3 regulates TGFBR2 signaling and fibrosis in dilated cardiomyopathy.

Authorship 1719708
type: Authorship
author rank in publication: 12
linked author: Seidman, Christine
linked information resource: Genetic diagnosis of facioscapulohumeral muscular dystrophy type 1 using rare-variant linkage analysis and long-read genome sequencing.

Authorship 1723473
type: Authorship
author rank in publication: 29
linked author: Seidman, Christine
linked information resource: Contribution of hypoxia-inducible factor 1alpha to pathogenesis of sarcomeric hypertrophic cardiomyopathy.

Contribution of hypoxia-inducible factor 1alpha to pathogenesis of sarcomeric hypertrophic cardiomyopathy.
PubMed Identifier: 39820339
author list: Raj Murthi S, Petry A, Shashikadze B, Stöckl JB, Schmid M, Santamaria G, Klingel K, Kracun D, Chen X, Bauer S, Schmitt JP, Flenkenthaler F, Gorham J, Toepfer CN, Potešil D, Hruška P, Zdráhal Z, Mayer Z, Klop M, Lehmann L, Qin Y, Papanakli L, Spielmann N, Moretti A, Fröhlich T, Ewert P, Holdenrieder S, Seidman JG, Seidman CE, Görlach A, Wolf CM
published in: Scientific reports
information resource reference: Contribution of hypoxia-inducible factor 1alpha to pathogenesis of sarcomeric hypertrophic cardiomyopathy. Sci Rep. 2025 01 16; 15(1):2132.
journal title abbreviation: Sci Rep
publication date: 2025-01-16T00:00:00
year: 2025
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 213449
type: Authorship
author rank in publication: 7
linked author: Seidman, Christine
linked information resource: Brazilian urban population genetic structure reveals a high degree of admixture.

Authorship 673501
type: Authorship
author rank in publication: 6
linked author: Seidman, Christine
linked information resource: An RNA-seq protocol to identify mRNA expression changes in mouse diaphyseal bone: applications in mice with bone property altering Lrp5 mutations.

Authorship 673907
type: Authorship
author rank in publication: 12
linked author: Seidman, Christine
linked information resource: HOXA2 haploinsufficiency in dominant bilateral microtia and hearing loss.

Authorship 678147
type: Authorship
author rank in publication: 2
linked author: Seidman, Christine
linked information resource: Conundrum of sudden cardiac death: making sense of missense.

HOXA2 haploinsufficiency in dominant bilateral microtia and hearing loss.
PubMed Identifier: 23775976
author list: Brown KK, Viana LM, Helwig CC, Artunduaga MA, Quintanilla-Dieck L, Jarrin P, Osorno G, McDonough B, DePalma SR, Eavey RD, Seidman JG, Seidman CE
published in: Human mutation
information resource reference: HOXA2 haploinsufficiency in dominant bilateral microtia and hearing loss. Hum Mutat. 2013 Oct; 34(10):1347-51.
journal title abbreviation: Hum Mutat
publication date: 2013-07-11T00:00:00
year: 2013
type: Academic Article
type: Article
type: Document
type: Information Resource

Conundrum of sudden cardiac death: making sense of missense.
PubMed Identifier: 23962865
author list: Ip JE, Seidman CE, Liu CF, Cheung JW, Thomas G, Markowitz SM, Lerman BB
published in: Circulation. Arrhythmia and electrophysiology
information resource reference: Conundrum of sudden cardiac death: making sense of missense. Circ Arrhythm Electrophysiol. 2013 Aug; 6(4):e58-63.
journal title abbreviation: Circ Arrhythm Electrophysiol
publication date: 2013-08-01T00:00:00
year: 2013
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 679154
type: Authorship
author rank in publication: 4
linked author: Seidman, Christine
linked information resource: Allele-specific silencing of mutant Myh6 transcripts in mice suppresses hypertrophic cardiomyopathy.

Allele-specific silencing of mutant Myh6 transcripts in mice suppresses hypertrophic cardiomyopathy.
PubMed Identifier: 24092743
author list: Jiang J, Wakimoto H, Seidman JG, Seidman CE
published in: Science (New York, N.Y.)
information resource reference: Allele-specific silencing of mutant Myh6 transcripts in mice suppresses hypertrophic cardiomyopathy. Science. 2013 Oct 04; 342(6154):111-4.
journal title abbreviation: Science
publication date: 2013-10-04T00:00:00
year: 2013
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 293908
type: Authorship
author rank in publication: 9
linked author: Seidman, Christine
linked information resource: A mouse model of human familial hypocalciuric hypercalcemia and neonatal severe hyperparathyroidism.

Authorship 296101
type: Authorship
author rank in publication: 7
linked author: Seidman, Christine
linked information resource: Effects of two familial hypertrophic cardiomyopathy-causing mutations on alpha-tropomyosin structure and function.

Authorship 689217
type: Authorship
author rank in publication: 30
linked author: Seidman, Christine
linked information resource: Assessing the phenotypic effects in the general population of rare variants in genes for a dominant Mendelian form of diabetes.

Assessing the phenotypic effects in the general population of rare variants in genes for a dominant Mendelian form of diabetes.
PubMed Identifier: 24097065
author list: Flannick J, Beer NL, Bick AG, Agarwala V, Molnes J, Gupta N, Burtt NP, Florez JC, Meigs JB, Taylor H, Lyssenko V, Irgens H, Fox E, Burslem F, Johansson S, Brosnan MJ, Trimmer JK, Newton-Cheh C, Tuomi T, Molven A, Wilson JG, O'Donnell CJ, Kathiresan S, Hirschhorn JN, Njølstad PR, Rolph T, Seidman JG, Gabriel S, Cox DR, Seidman CE, Groop L, Altshuler D
published in: Nature genetics
information resource reference: Assessing the phenotypic effects in the general population of rare variants in genes for a dominant Mendelian form of diabetes. Nat Genet. 2013 Nov; 45(11):1380-5.
journal title abbreviation: Nat Genet
publication date: 2013-10-06T00:00:00
year: 2013
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1736352
type: Authorship
author rank in publication: 24
linked author: Seidman, Christine
linked information resource: The cellular and molecular cardiac tissue responses in human inflammatory cardiomyopathies after SARS-CoV-2 infection and COVID-19 vaccination.

Authorship 1729355
type: Authorship
author rank in publication: 10
linked author: Seidman, Christine
linked information resource: Genes of the Fatty Acid Oxidation Pathway are Upregulated in Female as Compared to Male Cardiomyocytes.

Authorship 1730126
type: Authorship
author rank in publication: 7
linked author: Seidman, Christine
linked information resource: Deciphering the digenic architecture of congenital heart disease using trio exome sequencing data.

Authorship 1736089
type: Authorship
author rank in publication: 6
linked author: Seidman, Christine
linked information resource: Advances in the study and treatment of genetic cardiomyopathies.

Advances in the study and treatment of genetic cardiomyopathies.
PubMed Identifier: 39983674
author list: Parikh VN, Day SM, Lakdawala NK, Adler ED, Olivotto I, Seidman CE, Ho CY
published in: Cell
information resource reference: Advances in the study and treatment of genetic cardiomyopathies. Cell. 2025 Feb 20; 188(4):901-918.
journal title abbreviation: Cell
publication date: 2025-02-20T00:00:00
year: 2025
type: Academic Article
type: Article
type: Document
type: Information Resource

The cellular and molecular cardiac tissue responses in human inflammatory cardiomyopathies after SARS-CoV-2 infection and COVID-19 vaccination.
PubMed Identifier: 39994453
author list: Maatz H, Lindberg EL, Adami E, López-Anguita N, Perdomo-Sabogal A, Cocera Ortega L, Patone G, Reichart D, Myronova A, Schmidt S, Elsanhoury A, Klein O, Kühl U, Wyler E, Landthaler M, Yousefian S, Haas S, Kurth F, Teichmann SA, Oudit GY, Milting H, Noseda M, Seidman JG, Seidman CE, Heidecker B, Sander LE, Sawitzki B, Klingel K, Doeblin P, Kelle S, Van Linthout S, Hubner N, Tschöpe C
published in: Nature cardiovascular research
information resource reference: The cellular and molecular cardiac tissue responses in human inflammatory cardiomyopathies after SARS-CoV-2 infection and COVID-19 vaccination. Nat Cardiovasc Res. 2025 Mar; 4(3):330-345.
journal title abbreviation: Nat Cardiovasc Res
publication date: 2025-02-24T00:00:00
year: 2025
type: Academic Article
type: Article
type: Document
type: Information Resource

Genes of the Fatty Acid Oxidation Pathway are Upregulated in Female as Compared to Male Cardiomyocytes.
PubMed Identifier: 39960981
author list: Talukdar M, Chmátal L, Mao L, Reichart D, Murashige DS, Skaletsky H, DeLaughter DM, Arany Z, Seidman JG, Seidman CE, Page DC
published in: Circulation
information resource reference: Genes of the Fatty Acid Oxidation Pathway are Upregulated in Female as Compared to Male Cardiomyocytes. Circulation. 2025 Feb 18; 151(7):511-514.
journal title abbreviation: Circulation
publication date: 2025-02-17T00:00:00
year: 2025
type: Academic Article
type: Article
type: Document
type: Information Resource

Deciphering the digenic architecture of congenital heart disease using trio exome sequencing data.
PubMed Identifier: 39983722
author list: Kars ME, Stein D, Stenson PD, Cooper DN, Chung WK, Gruber PJ, Seidman CE, Shen Y, Tristani-Firouzi M, Gelb BD, Itan Y
published in: American journal of human genetics
information resource reference: Deciphering the digenic architecture of congenital heart disease using trio exome sequencing data. Am J Hum Genet. 2025 Mar 06; 112(3):583-598.
journal title abbreviation: Am J Hum Genet
publication date: 2025-02-20T00:00:00
year: 2025
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 692126
type: Authorship
author rank in publication: 10
linked author: Seidman, Christine
linked information resource: The role of mutant protein level in autosomal recessive catecholamine dependent polymorphic ventricular tachycardia (CPVT2).

The role of mutant protein level in autosomal recessive catecholamine dependent polymorphic ventricular tachycardia (CPVT2).
PubMed Identifier: 24070655
author list: Katz G, Shainberg A, Hochhauser E, Kurtzwald-Josefson E, Issac A, El-Ani D, Aravot D, Afek A, Seidman JG, Seidman CE, Eldar M, Arad M
published in: Biochemical pharmacology
information resource reference: The role of mutant protein level in autosomal recessive catecholamine dependent polymorphic ventricular tachycardia (CPVT2). Biochem Pharmacol. 2013 Dec 01; 86(11):1576-83.
journal title abbreviation: Biochem Pharmacol
publication date: 2013-09-23T00:00:00
year: 2013
type: Academic Article
type: Article
type: Document
type: Information Resource

Loss of FHL1 induces an age-dependent skeletal muscle myopathy associated with myofibrillar and intermyofibrillar disorganization in mice.
PubMed Identifier: 23975679
author list: Domenighetti AA, Chu PH, Wu T, Sheikh F, Gokhin DS, Guo LT, Cui Z, Peter AK, Christodoulou DC, Parfenov MG, Gorham JM, Li DY, Banerjee I, Lai X, Witzmann FA, Seidman CE, Seidman JG, Gomes AV, Shelton GD, Lieber RL, Chen J
published in: Human molecular genetics
information resource reference: Loss of FHL1 induces an age-dependent skeletal muscle myopathy associated with myofibrillar and intermyofibrillar disorganization in mice. Hum Mol Genet. 2014 Jan 01; 23(1):209-25.
journal title abbreviation: Hum Mol Genet
publication date: 2013-08-23T00:00:00
year: 2013
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 223827
type: Authorship
author rank in publication: 10
linked author: Seidman, Christine
linked information resource: Mapping a gene for familial hypertrophic cardiomyopathy to chromosome 14q1.

Proteomic Analysis of Valsartan for Attenuating Disease Evolution in Early Sarcomeric Hypertrophic Cardiomyopathy (VANISH) Clinical Trial.
PubMed Identifier: 40340372
author list: Topriceanu CC, Vissing CR, Axelsson Raja A, Day SM, Russell MW, Zahka K, Pereira AC, Colan SD, Murphy AM, Canter C, Bach RG, Wheeler MT, Rossano JW, Owens AT, Mestroni L, Taylor MRG, Moon JC, Captur G, Patel AR, Wilmot I, Soslow JH, Becker JR, Seidman CE, Lakdawala NK, Bundgaard H, Tahir UA, Ho CY
published in: Circulation. Heart failure
information resource reference: Proteomic Analysis of Valsartan for Attenuating Disease Evolution in Early Sarcomeric Hypertrophic Cardiomyopathy (VANISH) Clinical Trial. Circ Heart Fail. 2025 Jun; 18(6):e012393.
journal title abbreviation: Circ Heart Fail
publication date: 2025-05-09T00:00:00
year: 2025
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1738957
type: Authorship
author rank in publication: 17
linked author: Seidman, Christine
linked information resource: Modeling SMAD2 Mutations in Induced Pluripotent Stem Cells Provides Insights Into Cardiovascular Disease Pathogenesis.

Authorship 1739018
type: Authorship
author rank in publication: 37
linked author: Seidman, Christine
linked information resource: Recessive genetic contribution to congenital heart disease in 5,424 probands.

Authorship 1740295
type: Authorship
author rank in publication: 8
linked author: Seidman, Christine
linked information resource: GLP1R upregulation in mitral regurgitation observed at a single nucleus level.

Authorship 1740838
type: Authorship
author rank in publication: 44
linked author: Seidman, Christine
linked information resource: Genomic analysis of 11,555 probands identifies 60 dominant congenital heart disease genes.

Authorship 1743022
type: Authorship
author rank in publication: 11
linked author: Seidman, Christine
linked information resource: Efficient identification of de novo mutations in family trios: a consensus-based informatic approach.

Authorship 1742595
type: Authorship
author rank in publication: 23
linked author: Seidman, Christine
linked information resource: BMAL1-HIF2A heterodimer modulates circadian variations of myocardial injury.

Authorship 1747507
type: Authorship
author rank in publication: 23
linked author: Seidman, Christine
linked information resource: Proteomic Analysis of Valsartan for Attenuating Disease Evolution in Early Sarcomeric Hypertrophic Cardiomyopathy (VANISH) Clinical Trial.

Authorship 1747511
type: Authorship
author rank in publication: 15
linked author: Seidman, Christine
linked information resource: Mitochondrial NNT Promotes Diastolic Dysfunction in Cardiometabolic HFpEF.

Genomic analysis of 11,555 probands identifies 60 dominant congenital heart disease genes.
PubMed Identifier: 40127276
author list: Sierant MC, Jin SC, Bilguvar K, Morton SU, Dong W, Jiang W, Lu Z, Li B, López-Giráldez F, Tikhonova I, Zeng X, Lu Q, Choi J, Zhang J, Nelson-Williams C, Knight JR, Zhao H, Cao J, Mane S, Sedore SC, Gruber PJ, Lek M, Goldmuntz E, Deanfield J, Giardini A, Mital S, Russell M, Gaynor JW, King E, Wagner M, Srivastava D, Shen Y, Bernstein D, Porter GA, Newburger JW, Seidman JG, Roberts AE, Yandell M, Yost HJ, Tristani-Firouzi M, Kim R, Chung WK, Gelb BD, Seidman CE, Brueckner M, Lifton RP
published in: Proceedings of the National Academy of Sciences of the United States of America
information resource reference: Genomic analysis of 11,555 probands identifies 60 dominant congenital heart disease genes. Proc Natl Acad Sci U S A. 2025 Apr; 122(13):e2420343122.
journal title abbreviation: Proc Natl Acad Sci U S A
publication date: 2025-03-24T00:00:00
year: 2025
type: Academic Article
type: Article
type: Document
type: Information Resource

Modeling SMAD2 Mutations in Induced Pluripotent Stem Cells Provides Insights Into Cardiovascular Disease Pathogenesis.
PubMed Identifier: 40028843
author list: Ward T, Morton SU, Venturini G, Tai W, Jang MY, Gorham J, Delaughter D, Wasson LK, Khazal Z, Homsy J, Gelb BD, Chung WK, Bruneau BG, Brueckner M, Tristani-Firouzi M, DePalma SR, Seidman C, Seidman JG
published in: Journal of the American Heart Association
information resource reference: Modeling SMAD2 Mutations in Induced Pluripotent Stem Cells Provides Insights Into Cardiovascular Disease Pathogenesis. J Am Heart Assoc. 2025 Mar 04; 14(5):e036860.
journal title abbreviation: J Am Heart Assoc
publication date: 2025-03-03T00:00:00
year: 2025
type: Academic Article
type: Article
type: Document
type: Information Resource

Recessive genetic contribution to congenital heart disease in 5,424 probands.
PubMed Identifier: 40030011
author list: Dong W, Jin SC, Sierant MC, Lu Z, Li B, Lu Q, Morton SU, Zhang J, López-Giráldez F, Nelson-Williams C, Knight JR, Zhao H, Cao J, Mane S, Gruber PJ, Lek M, Goldmuntz E, Deanfield J, Giardini A, Mital S, Russell M, Gaynor JW, Cnota JF, Wagner M, Srivastava D, Bernstein D, Porter GA, Newburger J, Roberts AE, Yandell M, Yost HJ, Tristani-Firouzi M, Kim R, Seidman J, Chung WK, Gelb BD, Seidman CE, Lifton RP, Brueckner M
published in: Proceedings of the National Academy of Sciences of the United States of America
information resource reference: Recessive genetic contribution to congenital heart disease in 5,424 probands. Proc Natl Acad Sci U S A. 2025 Mar 11; 122(10):e2419992122.
journal title abbreviation: Proc Natl Acad Sci U S A
publication date: 2025-03-03T00:00:00
year: 2025
type: Academic Article
type: Article
type: Document
type: Information Resource

GLP1R upregulation in mitral regurgitation observed at a single nucleus level.
PubMed Identifier: 40209981
author list: Tiwari S, Beyer M, Aranki SF, Neyazi M, Oudit GY, Layton O, Seidman JG, Seidman CE, Muehlschlegel JD
published in: Journal of molecular and cellular cardiology
information resource reference: GLP1R upregulation in mitral regurgitation observed at a single nucleus level. J Mol Cell Cardiol. 2025 Jun; 203:7-9.
journal title abbreviation: J Mol Cell Cardiol
publication date: 2025-04-08T00:00:00
year: 2025
type: Academic Article
type: Article
type: Document
type: Information Resource

Mitochondrial NNT Promotes Diastolic Dysfunction in Cardiometabolic HFpEF.
PubMed Identifier: 40340422
author list: Pepin ME, Konrad PJM, Nazir S, Bazgir F, Maack C, Nickel A, Gorman JM, Hohl M, Schreiter F, Dewenter M, de Britto Chaves Filho A, Schulze A, Karlstaedt A, Frey N, Seidman CE, Seidman JG, Backs J
published in: Circulation research
information resource reference: Mitochondrial NNT Promotes Diastolic Dysfunction in Cardiometabolic HFpEF. Circ Res. 2025 Jun 06; 136(12):1564-1578.
journal title abbreviation: Circ Res
publication date: 2025-05-09T00:00:00
year: 2025
type: Academic Article
type: Article
type: Document
type: Information Resource

Efficient identification of de novo mutations in family trios: a consensus-based informatic approach.
PubMed Identifier: 40155050
author list: Shadrina M, Kalay Ö, Demirkaya-Budak S, LeDuc CA, Chung WK, Turgut D, Budak G, Arslan E, Semenyuk V, Davis-Dusenbery B, Seidman CE, Yost HJ, Jain A, Gelb BD
published in: Life science alliance
information resource reference: Efficient identification of de novo mutations in family trios: a consensus-based informatic approach. Life Sci Alliance. 2025 Jun; 8(6).
journal title abbreviation: Life Sci Alliance
publication date: 2025-03-28T00:00:00
year: 2025
type: Academic Article
type: Article
type: Document
type: Information Resource

BMAL1-HIF2A heterodimer modulates circadian variations of myocardial injury.
PubMed Identifier: 40269168
author list: Ruan W, Li T, Bang IH, Lee J, Deng W, Ma X, Luo C, Du F, Yoo SH, Kim B, Li J, Yuan X, Figarella K, An YA, Wang YY, Liang Y, DeBerge M, Zhang D, Zhou Z, Wang Y, Gorham JM, Seidman JG, Seidman CE, Aranki SF, Nair R, Li L, Narula J, Zhao Z, Gorfe AA, Muehlschlegel JD, Tsai KL, Eltzschig HK
published in: Nature
information resource reference: BMAL1-HIF2A heterodimer modulates circadian variations of myocardial injury. Nature. 2025 05; 641(8064):1017-1028.
journal title abbreviation: Nature
publication date: 2025-04-23T00:00:00
year: 2025
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 697378
type: Authorship
author rank in publication: 16
linked author: Seidman, Christine
linked information resource: Loss of FHL1 induces an age-dependent skeletal muscle myopathy associated with myofibrillar and intermyofibrillar disorganization in mice.

Authorship 1753000
type: Authorship
author rank in publication: 19
linked author: Seidman, Christine
linked information resource: Empagliflozin enhances metabolic efficiency and improves left ventricular hypertrophy in a hypertrophic cardiomyopathy mouse model.

Empagliflozin enhances metabolic efficiency and improves left ventricular hypertrophy in a hypertrophic cardiomyopathy mouse model.
PubMed Identifier: 40396194
author list: Baka T, Moore J, Qin F, Yurista SR, Zhang A, He H, Chambers JM, Croteau D, Goel RK, Smith H, Wang MC, Chen CS, Hobai IA, Rombaldova M, Kuda O, Tardiff JC, Balschi JA, Pimentel DR, Seidman CE, Seidman JG, Emili A, Colucci WS, Luptak I
published in: European heart journal
information resource reference: Empagliflozin enhances metabolic efficiency and improves left ventricular hypertrophy in a hypertrophic cardiomyopathy mouse model. Eur Heart J. 2025 Oct 22; 46(40):4105-4119.
journal title abbreviation: Eur Heart J
publication date: 2025-10-22T00:00:00
year: 2025
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 202504
type: Authorship
author rank in publication: 2
linked author: Seidman, Christine
linked information resource: Transcription factor haploinsufficiency: when half a loaf is not enough.

Authorship 204868
type: Authorship
author rank in publication: 9
linked author: Seidman, Christine
linked information resource: Constitutively active AMP kinase mutations cause glycogen storage disease mimicking hypertrophic cardiomyopathy.

Authorship 700197
type: Authorship
author rank in publication: 2
linked author: Seidman, Christine
linked information resource: Genetics and disease of ventricular muscle.

Genetics and disease of ventricular muscle.
PubMed Identifier: 24384818
author list: Fatkin D, Seidman CE, Seidman JG
published in: Cold Spring Harbor perspectives in medicine
information resource reference: Genetics and disease of ventricular muscle. Cold Spring Harb Perspect Med. 2014 Jan 01; 4(1):a021063.
journal title abbreviation: Cold Spring Harb Perspect Med
publication date: 2014-01-01T00:00:00
year: 2014
type: Academic Article
type: Article
type: Document
type: Information Resource

Plasma Proteomics Reveals Dysregulated Pathways Across the Spectrum LMNA Cardiomyopathy.
PubMed Identifier: 40509996
author list: Tahir UA, Reichart D, Purohit A, Barber JL, Tiwari G, Farrell L, Marine JE, Roy D, Patel J, Ireland CG, Ho CY, Seidman CE, Gerszten RE, Lakdawala NK
published in: Circulation. Genomic and precision medicine
information resource reference: Plasma Proteomics Reveals Dysregulated Pathways Across the Spectrum LMNA Cardiomyopathy. Circ Genom Precis Med. 2025 Aug; 18(4):e004924.
journal title abbreviation: Circ Genom Precis Med
publication date: 2025-06-13T00:00:00
year: 2025
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 703636
type: Authorship
author rank in publication: 6
linked author: Seidman, Christine
linked information resource: Deep sequence analysis of gene expression identifies osteopontin as a downstream effector of integrin-linked kinase (ILK) in cardiac-specific ILK knockout mice.

Deep sequence analysis of gene expression identifies osteopontin as a downstream effector of integrin-linked kinase (ILK) in cardiac-specific ILK knockout mice.
PubMed Identifier: 24319095
author list: Dai J, Matsui T, Abel ED, Dedhar S, Gerszten RE, Seidman CE, Seidman JG, Rosenzweig A
published in: Circulation. Heart failure
information resource reference: Deep sequence analysis of gene expression identifies osteopontin as a downstream effector of integrin-linked kinase (ILK) in cardiac-specific ILK knockout mice. Circ Heart Fail. 2014 Jan; 7(1):184-93.
journal title abbreviation: Circ Heart Fail
publication date: 2013-12-06T00:00:00
year: 2013
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 269843
type: Authorship
author rank in publication: 6
linked author: Seidman, Christine
linked information resource: Causes of clinical diversity in human TBX5 mutations.

Authorship 239587
type: Authorship
author rank in publication: 1
linked author: Seidman, Christine
linked information resource: Introduction of plasmid DNA into cells.

Authorship 281267
type: Authorship
author rank in publication: 14
linked author: Seidman, Christine
linked information resource: Cardiomyopathy in Irx4-deficient mice is preceded by abnormal ventricular gene expression.

5'RNA-Seq identifies Fhl1 as a genetic modifier in cardiomyopathy.
PubMed Identifier: 24509080
author list: Christodoulou DC, Wakimoto H, Onoue K, Eminaga S, Gorham JM, DePalma SR, Herman DS, Teekakirikul P, Conner DA, McKean DM, Domenighetti AA, Aboukhalil A, Chang S, Srivastava G, McDonough B, De Jager PL, Chen J, Bulyk ML, Muehlschlegel JD, Seidman CE, Seidman JG
published in: The Journal of clinical investigation
information resource reference: 5'RNA-Seq identifies Fhl1 as a genetic modifier in cardiomyopathy. J Clin Invest. 2014 Mar; 124(3):1364-70.
journal title abbreviation: J Clin Invest
publication date: 2014-02-10T00:00:00
year: 2014
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 257796
type: Authorship
author rank in publication: 1
linked author: Seidman, Christine
linked information resource: Genetic causes of inherited cardiac hypertrophy: Robert L. Frye Lecture.

Authorship 266343
type: Authorship
author rank in publication: 24
linked author: Seidman, Christine
linked information resource: Burden of rare sarcomere gene variants in the Framingham and Jackson Heart Study cohorts.

Authorship 266650
type: Authorship
author rank in publication: 8
linked author: Seidman, Christine
linked information resource: Congenital heart disease caused by mutations in the transcription factor NKX2-5.

Authorship 267586
type: Authorship
author rank in publication: 6
linked author: Seidman, Christine
linked information resource: Locus for familial migrainous vertigo disease maps to chromosome 5q35.

Authorship 306622
type: Authorship
author rank in publication: 1
linked author: Seidman, Christine
linked information resource: Molecular approaches to the study of atrial natriuretic factor.

Effects of losartan on left ventricular hypertrophy and fibrosis in patients with nonobstructive hypertrophic cardiomyopathy.
PubMed Identifier: 24621999
author list: Shimada YJ, Passeri JJ, Baggish AL, O'Callaghan C, Lowry PA, Yannekis G, Abbara S, Ghoshhajra BB, Rothman RD, Ho CY, Januzzi JL, Seidman CE, Fifer MA
published in: JACC. Heart failure
information resource reference: Effects of losartan on left ventricular hypertrophy and fibrosis in patients with nonobstructive hypertrophic cardiomyopathy. JACC Heart Fail. 2013 Dec; 1(6):480-7.
journal title abbreviation: JACC Heart Fail
publication date: 2013-10-24T00:00:00
year: 2013
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 313030
type: Authorship
author rank in publication: 14
linked author: Seidman, Christine
linked information resource: Transcription factor genes Smad4 and Gata4 cooperatively regulate cardiac valve development. [corrected]

Authorship 209533
type: Authorship
author rank in publication: 18
linked author: Seidman, Christine
linked information resource: Transgenic mice overexpressing mutant PRKAG2 define the cause of Wolff-Parkinson-White syndrome in glycogen storage cardiomyopathy.

Engineered human induced pluripotent stem cell models reveal altered podocytogenesis in congenital heart disease-associated SMAD2 mutations.
PubMed Identifier: 41184605
author list: Bhattacharya R, Ward T, Kalejaiye TD, Mishra A, Leeman SM, Arzaghi H, Seidman JG, Seidman CE, Musah S
published in: Nature biomedical engineering
information resource reference: Engineered human induced pluripotent stem cell models reveal altered podocytogenesis in congenital heart disease-associated SMAD2 mutations. Nat Biomed Eng. 2025 Nov 03.
journal title abbreviation: Nat Biomed Eng
publication date: 2025-11-03T00:00:00
year: 2025
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 479968
type: Authorship
author rank in publication: 8
linked author: Seidman, Christine
linked information resource: Cardiac expression of the ventricle-specific homeobox gene Irx4 is modulated by Nkx2-5 and dHand.

Authorship 712760
type: Authorship
author rank in publication: 16
linked author: Seidman, Christine
linked information resource: A common genetic variant within SCN10A modulates cardiac SCN5A expression.

Authorship 712745
type: Authorship
author rank in publication: 12
linked author: Seidman, Christine
linked information resource: Effects of losartan on left ventricular hypertrophy and fibrosis in patients with nonobstructive hypertrophic cardiomyopathy.

Authorship 716183
type: Authorship
author rank in publication: 1
linked author: Seidman, Christine
linked information resource: A conversation with Christine Seidman. Interview by Ushma S. Neill.

Authorship 721894
type: Authorship
author rank in publication: 15
linked author: Seidman, Christine
linked information resource: The Congenital Heart Disease Genetic Network Study: rationale, design, and early results.

Authorship 724309
type: Authorship
author rank in publication: 19
linked author: Seidman, Christine
linked information resource: Increased burden of cardiovascular disease in carriers of APOL1 genetic variants.

Authorship 720669
type: Authorship
author rank in publication: 20
linked author: Seidman, Christine
linked information resource: 5'RNA-Seq identifies Fhl1 as a genetic modifier in cardiomyopathy.

Authorship 720251
type: Authorship
author rank in publication: 15
linked author: Seidman, Christine
linked information resource: The MedSeq Project: a randomized trial of integrating whole genome sequencing into clinical medicine.

The Congenital Heart Disease Genetic Network Study: rationale, design, and early results.
PubMed Identifier: 23410879
author list: Gelb B, Brueckner M, Chung W, Goldmuntz E, Kaltman J, Kaski JP, Kim R, Kline J, Mercer-Rosa L, Porter G, Roberts A, Rosenberg E, Seiden H, Seidman C, Sleeper L, Tennstedt S, Kaltman J, Schramm C, Burns K, Pearson G, Rosenberg E
published in: Circulation research
information resource reference: The Congenital Heart Disease Genetic Network Study: rationale, design, and early results. Circ Res. 2013 Feb 15; 112(4):698-706.
journal title abbreviation: Circ Res
publication date: 2013-02-15T00:00:00
year: 2013
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 338900
type: Authorship
author rank in publication: 3
linked author: Seidman, Christine
linked information resource: Mutations in CD2BP1 disrupt binding to PTP PEST and are responsible for PAPA syndrome, an autoinflammatory disorder.

Increased burden of cardiovascular disease in carriers of APOL1 genetic variants.
PubMed Identifier: 24379297
author list: Ito K, Bick AG, Flannick J, Friedman DJ, Genovese G, Parfenov MG, Depalma SR, Gupta N, Gabriel SB, Taylor HA, Fox ER, Newton-Cheh C, Kathiresan S, Hirschhorn JN, Altshuler DM, Pollak MR, Wilson JG, Seidman JG, Seidman C
published in: Circulation research
information resource reference: Increased burden of cardiovascular disease in carriers of APOL1 genetic variants. Circ Res. 2014 Feb 28; 114(5):845-50.
journal title abbreviation: Circ Res
publication date: 2013-12-30T00:00:00
year: 2013
type: Academic Article
type: Article
type: Document
type: Information Resource

A conversation with Christine Seidman. Interview by Ushma S. Neill.
PubMed Identifier: 23863632
author list: Seidman C
published in: The Journal of clinical investigation
information resource reference: A conversation with Christine Seidman. Interview by Ushma S. Neill. J Clin Invest. 2013 Jul; 123(7):2754-5.
journal title abbreviation: J Clin Invest
publication date: 2013-07-01T00:00:00
year: 2013
type: Academic Article
type: Article
type: Document
type: Information Resource

The MedSeq Project: a randomized trial of integrating whole genome sequencing into clinical medicine.
PubMed Identifier: 24645908
author list: Vassy JL, Lautenbach DM, McLaughlin HM, Kong SW, Christensen KD, Krier J, Kohane IS, Feuerman LZ, Blumenthal-Barby J, Roberts JS, Lehmann LS, Ho CY, Ubel PA, MacRae CA, Seidman CE, Murray MF, McGuire AL, Rehm HL, Green RC
published in: Trials
information resource reference: The MedSeq Project: a randomized trial of integrating whole genome sequencing into clinical medicine. Trials. 2014 Mar 20; 15:85.
journal title abbreviation: Trials
publication date: 2014-03-20T00:00:00
year: 2014
type: Academic Article
type: Article
type: Document
type: Information Resource

A common genetic variant within SCN10A modulates cardiac SCN5A expression.
PubMed Identifier: 24642470
author list: van den Boogaard M, Smemo S, Burnicka-Turek O, Arnolds DE, van de Werken HJ, Klous P, McKean D, Muehlschlegel JD, Moosmann J, Toka O, Yang XH, Koopmann TT, Adriaens ME, Bezzina CR, de Laat W, Seidman C, Seidman JG, Christoffels VM, Nobrega MA, Barnett P, Moskowitz IP
published in: The Journal of clinical investigation
information resource reference: A common genetic variant within SCN10A modulates cardiac SCN5A expression. J Clin Invest. 2014 Apr; 124(4):1844-52.
journal title abbreviation: J Clin Invest
publication date: 2014-03-18T00:00:00
year: 2014
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 231026
type: Authorship
author rank in publication: 2
linked author: Seidman, Christine
linked information resource: Human fatty acid synthesis is reduced after the substitution of dietary starch for sugar.

Authorship 27217
type: Authorship
author rank in publication: 3
linked author: Seidman, Christine
linked information resource: Human fatty acid synthesis is stimulated by a eucaloric low fat, high carbohydrate diet.

Authorship 276299
type: Authorship
author rank in publication: 3
linked author: Seidman, Christine
linked information resource: Narrative review: harnessing molecular genetics for the diagnosis and management of hypertrophic cardiomyopathy.

Authorship 93081
type: Authorship
author rank in publication: 7
linked author: Seidman, Christine
linked information resource: Activation of multiple signaling pathways causes developmental defects in mice with a Noonan syndrome–associated Sos1 mutation.

Authorship 312135
type: Authorship
author rank in publication: 4
linked author: Seidman, Christine
linked information resource: Altered regulatory function of two familial hypertrophic cardiomyopathy troponin T mutants.

Authorship 299833
type: Authorship
author rank in publication: 10
linked author: Seidman, Christine
linked information resource: Dilated cardiomyopathy and heart failure caused by a mutation in phospholamban.

Authorship 192670
type: Authorship
author rank in publication: 2
linked author: Seidman, Christine
linked information resource: Expression and functional assessment of a truncated cardiac troponin T that causes hypertrophic cardiomyopathy. Evidence for a dominant negative action.

Authorship 735190
type: Authorship
author rank in publication: 10
linked author: Seidman, Christine
linked information resource: UBQLN2 mutation causing heterogeneous X-linked dominant neurodegeneration.

UBQLN2 mutation causing heterogeneous X-linked dominant neurodegeneration.
PubMed Identifier: 24771548
author list: Fahed AC, McDonough B, Gouvion CM, Newell KL, Dure LS, Bebin M, Bick AG, Seidman JG, Harter DH, Seidman CE
published in: Annals of neurology
information resource reference: UBQLN2 mutation causing heterogeneous X-linked dominant neurodegeneration. Ann Neurol. 2014 May; 75(5):793-798.
journal title abbreviation: Ann Neurol
publication date: 2014-05-09T00:00:00
year: 2014
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1777222
type: Authorship
author rank in publication: 12
linked author: Seidman, Christine
linked information resource: Plasma Proteomics Reveals Dysregulated Pathways Across the Spectrum LMNA Cardiomyopathy.

Authorship 1780137
type: Authorship
author rank in publication: 8
linked author: Seidman, Christine
linked information resource: Engineered human induced pluripotent stem cell models reveal altered podocytogenesis in congenital heart disease-associated SMAD2 mutations.

Authorship 735783
type: Authorship
author rank in publication: 15
linked author: Seidman, Christine
linked information resource: 126 Advanced Assessment of Cardiac Morphology and Prediction of Gene Carriage by CMR in Hypertrophic Cardiomyopathy - The HCMNET/UCL Collaboration.

Authorship 736483
type: Authorship
author rank in publication: 5
linked author: Seidman, Christine
linked information resource: Biobank participants' preferences for disclosure of genetic research results: perspectives from the OurGenes, OurHealth, OurCommunity project.

Biobank participants' preferences for disclosure of genetic research results: perspectives from the OurGenes, OurHealth, OurCommunity project.
PubMed Identifier: 24943692
author list: Allen NL, Karlson EW, Malspeis S, Lu B, Seidman CE, Lehmann LS
published in: Mayo Clinic proceedings
information resource reference: Biobank participants' preferences for disclosure of genetic research results: perspectives from the OurGenes, OurHealth, OurCommunity project. Mayo Clin Proc. 2014 Jun; 89(6):738-46.
journal title abbreviation: Mayo Clin Proc
publication date: 2014-06-01T00:00:00
year: 2014
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 282453
type: Authorship
author rank in publication: 8
linked author: Seidman, Christine
linked information resource: Cardiac myosin-binding protein-C phosphorylation and cardiac function.

126 Advanced Assessment of Cardiac Morphology and Prediction of Gene Carriage by CMR in Hypertrophic Cardiomyopathy - The HCMNET/UCL Collaboration.
PubMed Identifier: 24922922
author list: Captur G, Mohun TJ, Finocchiaro G, Wilson R, Levine J, Conner L, Lopes L, Patel V, Sado DM, Li C, Bassett P, Herrey A, Tome Esteban M, McKenna WJ, Seidman C, Muthurangu V, Bluemke DA, Ho CY, Elliott PM, Moon JC
published in: Heart (British Cardiac Society)
information resource reference: 126 Advanced Assessment of Cardiac Morphology and Prediction of Gene Carriage by CMR in Hypertrophic Cardiomyopathy - The HCMNET/UCL Collaboration. Heart. 2014 Jun; 100 Suppl 3:A72-3.
journal title abbreviation: Heart
publication date: 2014-06-01T00:00:00
year: 2014
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 247899
type: Authorship
author rank in publication: 6
linked author: Seidman, Christine
linked information resource: https://connects.catalyst.harvard.edu/Profiles/profile/904411

Authorship 288658
type: Authorship
author rank in publication: 1
linked author: Seidman, Christine
linked information resource: Introduction of plasmid DNA into cells.

Authorship 1811299
type: Authorship
author rank in publication: 22
linked author: Seidman, Christine
linked information resource: Regulatory T cells attenuate chronic inflammation and cardiac fibrosis in hypertrophic cardiomyopathy.

Authorship 1819491
type: Authorship
author rank in publication: 12
linked author: Seidman, Christine
linked information resource: Cell shape and maturation impacts a-actinin-2 tension in iPSC-derived cardiomyocytes.

Authorship 1823745
type: Authorship
author rank in publication: 14
linked author: Seidman, Christine
linked information resource: Genomic rare variant mechanisms for congenital cardiac laterality defect: A digenic model approach.

Authorship 1846542
type: Authorship
author rank in publication: 129
linked author: Seidman, Christine
linked information resource: Titin-related familial dilated cardiomyopathy: factors associated with disease onset.

Genomic rare variant mechanisms for congenital cardiac laterality defect: A digenic model approach.
PubMed Identifier: 40543504
author list: Rai A, Klonowski J, Yuan B, Coveler KJ, Dardas Z, Egab I, Xu J, Lupo PJ, Agopian AJ, Kostka D, Lo CW, Yi SS, Gelb BD, Seidman CE, Boerwinkle E, Posey JE, Gibbs RA, Lupski JR, Morris SA, Coban-Akdemir Z
published in: American journal of human genetics
information resource reference: Genomic rare variant mechanisms for congenital cardiac laterality defect: A digenic model approach. Am J Hum Genet. 2025 Jul 03; 112(7):1664-1680.
journal title abbreviation: Am J Hum Genet
publication date: 2025-06-20T00:00:00
year: 2025
type: Academic Article
type: Article
type: Document
type: Information Resource

Cell shape and maturation impacts a-actinin-2 tension in iPSC-derived cardiomyocytes.
PubMed Identifier: 41695113
author list: Dutta PK, Toth JM, Sundaram S, Chen X, Chopra A, Ewoldt JK, Cloonan P, Gao X, LaCroix AS, Hoffman BD, Shenoy VB, Seidman CE, Seidman JG, Chen CS, Eyckmans J
published in: APL bioengineering
information resource reference: Cell shape and maturation impacts a-actinin-2 tension in iPSC-derived cardiomyocytes. APL Bioeng. 2026 Mar; 10(1):016109.
journal title abbreviation: APL Bioeng
publication date: 2026-02-11T00:00:00
year: 2026
type: Academic Article
type: Article
type: Document
type: Information Resource

Titin-related familial dilated cardiomyopathy: factors associated with disease onset.
PubMed Identifier: 40796136
author list: Johnson R, Fletcher RA, Peters S, Ohanian M, Soka M, Smolnikov A, Abihider KE, Ackerman MJ, Ader F, Akhtar MM, Amin AS, Ashley EA, Atherton JJ, Austin R, Baas AF, Bagnall RD, Ross SB, Blouin JL, Brown EE, Bundgaard H, Cannie D, Chmielewski P, Correnti G, Crespo-Leiro MG, Dal Ferro M, Dellefave-Castillo LM, Dominguez F, Dooijes D, Dybro AM, Ed Demri Y, El Hachmi M, Escobar-Lopez L, Foye SJ, Franaszczyk M, Gigli M, Lopez EG, Goudal A, Graw S, Guipponi M, Haan E, Haas J, Hammersley DJ, Hansen FG, Hayward CS, Hey TM, Heymans S, Ho CY, Houweling AC, Ingles J, Ingrey A, Jabbour A, James PA, Jansweijer JA, Jongbloed JDH, Keogh AM, Larrañaga-Moreira JM, Lekanne Deprez RH, Macciocca I, Macdonald PS, Mansencal N, Mansour J, Martinez-Veira C, McDonough B, McGaughran J, Medo K, Merlo M, Michalak E, Monserrat L, Mountain H, Muller SA, Murphy AM, Murray B, Oates EC, Ormondroyd E, Pachter N, Paldino A, Palmyre A, Pereira NL, Picard KC, Poplawski N, Prasad S, Proukhnitzky J, Pruny JF, Reant P, Richard P, Ronan A, Sedaghat-Hamedani F, Semsarian C, Storm G, Stroeks S, Syrris P, Taylor MRG, Thomson K, Thompson T, van Tintelen JP, Vissing CR, Waddell-Smith KE, Wallis M, Zentner D, Arnott C, Marian AJ, Oh J, Fokstuen S, James CA, Barriales-Villa R, Meder B, Wahbi K, Giudicessi JR, Parikh VN, Ware JS, Piriou N, Rooryck C, Lakdawala NK, Mestroni L, Sinagra G, Elliott PM, Watkins H, McNally EM, Charron P, van Spaendonck-Zwarts KY, Garcia-Pavia P, Peña-Peña ML, Mogensen J, Christensen AH, Bilinska ZT, Rasmussen TB, Seidman JG, Seidman CE, Te Riele ASJM, Verdonschot JAJ, Pinto YM, Christiaans I, Fatkin D
published in: European heart journal
information resource reference: Titin-related familial dilated cardiomyopathy: factors associated with disease onset. Eur Heart J. 2025 Dec 22; 46(48):5240-5257.
journal title abbreviation: Eur Heart J
publication date: 2025-12-22T00:00:00
year: 2025
type: Academic Article
type: Article
type: Document
type: Information Resource

Regulatory T cells attenuate chronic inflammation and cardiac fibrosis in hypertrophic cardiomyopathy.
PubMed Identifier: 40632839
author list: Wang YJ, Singh K, Lokman AB, Deng S, Sunitha B, Coelho Lima J, Beglov J, Kelly M, Blease A, Fung JCK, Huang A, Attar M, Stork LA, Maguire ML, Schneider JE, Marston SB, Soilleux EJ, Dendrou CA, Coles M, Buckley CD, Seidman JG, Seidman CE, Redwood C, Ashrafian H, Watkins H
published in: Science translational medicine
information resource reference: Regulatory T cells attenuate chronic inflammation and cardiac fibrosis in hypertrophic cardiomyopathy. Sci Transl Med. 2025 Jul 09; 17(806):eadq3516.
journal title abbreviation: Sci Transl Med
publication date: 2025-07-09T00:00:00
year: 2025
type: Academic Article
type: Article
type: Document
type: Information Resource

Newborn Medicine
type: Division
type: Organization

Authorship 156966
type: Authorship
author rank in publication: 1
linked author: Seidman, Christine
linked information resource: Mutations in cardiac myosin heavy chain genes cause familial hypertrophic cardiomyopathy.

Authorship 739451
type: Authorship
author rank in publication: 6
linked author: Seidman, Christine
linked information resource: ß-Myosin heavy chain variant Val606Met causes very mild hypertrophic cardiomyopathy in mice, but exacerbates HCM phenotypes in mice carrying other HCM mutations.

ß-Myosin heavy chain variant Val606Met causes very mild hypertrophic cardiomyopathy in mice, but exacerbates HCM phenotypes in mice carrying other HCM mutations.
PubMed Identifier: 24829265
author list: Blankenburg R, Hackert K, Wurster S, Deenen R, Seidman JG, Seidman CE, Lohse MJ, Schmitt JP
published in: Circulation research
information resource reference: ß-Myosin heavy chain variant Val606Met causes very mild hypertrophic cardiomyopathy in mice, but exacerbates HCM phenotypes in mice carrying other HCM mutations. Circ Res. 2014 Jul 07; 115(2):227-37.
journal title abbreviation: Circ Res
publication date: 2014-05-14T00:00:00
year: 2014
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 345399
type: Authorship
author rank in publication: 1
linked author: Seidman, Christine
linked information resource: Identifying sarcomere gene mutations in hypertrophic cardiomyopathy: a personal history.

Authorship 377060
type: Authorship
author rank in publication: 19
linked author: Seidman, Christine
linked information resource: Missense mutations in the BCS1L gene as a cause of the Björnstad syndrome.

Authorship 316604
type: Authorship
author rank in publication: 8
linked author: Seidman, Christine
linked information resource: Alpha-tropomyosin and cardiac troponin T mutations cause familial hypertrophic cardiomyopathy: a disease of the sarcomere.

Instructor in Pediatrics
is primary position: true
position in department: Pediatrics
position in division: Genetics
sort order: 1
type: Position
HR job title: Instructor in Pediatrics
position in organization: Boston Children's Hospital

Assistant Professor of Pediatrics
is primary position: true
position in department: Pediatrics
position in division: Newborn Medicine
sort order: 1
type: Position
HR job title: Assistant Professor of Pediatrics
position in organization: Boston Children's Hospital

Authorship 288030
type: Authorship
author rank in publication: 5
linked author: Seidman, Christine
linked information resource: Diastolic dysfunction and altered energetics in the alphaMHC403/+ mouse model of familial hypertrophic cardiomyopathy.

Authorship 314786
type: Authorship
author rank in publication: 9
linked author: Seidman, Christine
linked information resource: Deletion of thioredoxin-interacting protein in mice impairs mitochondrial function but protects the myocardium from ischemia-reperfusion injury.

Authorship 32145
type: Authorship
author rank in publication: 6
linked author: Seidman, Christine
linked information resource: Exercise training improves cardiac function and attenuates arrhythmia in CPVT mice.

Authorship 439851
type: Authorship
author rank in publication: 6
linked author: Seidman, Christine
linked information resource: Atrial natriuretic factor gene expression in ventricles of rats with spontaneous biventricular hypertrophy.

Authorship 444375
type: Authorship
author rank in publication: 3
linked author: Seidman, Christine
linked information resource: Cardiovascular genomics.

Authorship 375504
type: Authorship
author rank in publication: 4
linked author: Seidman, Christine
linked information resource: Single-molecule mechanics of R403Q cardiac myosin isolated from the mouse model of familial hypertrophic cardiomyopathy.

Authorship 750172
type: Authorship
author rank in publication: 8
linked author: Seidman, Christine
linked information resource: Alpha blockade potentiates CPVT therapy in calsequestrin-mutant mice.

Authorship 747248
type: Authorship
author rank in publication: 3
linked author: Seidman, Christine
linked information resource: Echocardiography and cardiac MRI in mutation-negative hypertrophic cardiomyopathy in an older patient: a case defining the need for ICD.

Alpha blockade potentiates CPVT therapy in calsequestrin-mutant mice.
PubMed Identifier: 24768611
author list: Kurtzwald-Josefson E, Hochhauser E, Bogachenko K, Harun-Khun S, Katz G, Aravot D, Seidman JG, Seidman CE, Eldar M, Shainberg A, Arad M
published in: Heart rhythm
information resource reference: Alpha blockade potentiates CPVT therapy in calsequestrin-mutant mice. Heart Rhythm. 2014 Aug; 11(8):1471-9.
journal title abbreviation: Heart Rhythm
publication date: 2014-04-21T00:00:00
year: 2014
type: Academic Article
type: Article
type: Document
type: Information Resource

Echocardiography and cardiac MRI in mutation-negative hypertrophic cardiomyopathy in an older patient: a case defining the need for ICD.
PubMed Identifier: 24816179
author list: Rodriguez F, Degnan KO, Seidman CE, Mangion JR
published in: Echocardiography (Mount Kisco, N.Y.)
information resource reference: Echocardiography and cardiac MRI in mutation-negative hypertrophic cardiomyopathy in an older patient: a case defining the need for ICD. Echocardiography. 2014 Aug; 31(7):E204-6.
journal title abbreviation: Echocardiography
publication date: 2014-05-10T00:00:00
year: 2014
type: Academic Article
type: Article
type: Document
type: Information Resource

Nationwide study on hypertrophic cardiomyopathy in Iceland: evidence of a MYBPC3 founder mutation.
PubMed Identifier: 25078086
author list: Adalsteinsdottir B, Teekakirikul P, Maron BJ, Burke MA, Gudbjartsson DF, Holm H, Stefansson K, DePalma SR, Mazaika E, McDonough B, Danielsen R, Seidman JG, Seidman CE, Gunnarsson GT
published in: Circulation
information resource reference: Nationwide study on hypertrophic cardiomyopathy in Iceland: evidence of a MYBPC3 founder mutation. Circulation. 2014 Sep 30; 130(14):1158-67.
journal title abbreviation: Circulation
publication date: 2014-07-30T00:00:00
year: 2014
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 517184
type: Authorship
author rank in publication: 7
linked author: Seidman, Christine
linked information resource: An evaluation of ribonuclease protection assays for the detection of beta-cardiac myosin heavy chain gene mutations.

Authorship 754681
type: Authorship
author rank in publication: 13
linked author: Seidman, Christine
linked information resource: The imperative to invest in science has never been greater.

The imperative to invest in science has never been greater.
PubMed Identifier: 25180532
author list: Carethers JM, Coughlin S, Diamond B, Erzurum S, Fried LP, Jameson JL, Kaushansky K, Klotman ME, Lemon S, Mitchell B, Rothman P, Sawyers C, Seidman C, Somlo S
published in: The Journal of clinical investigation
information resource reference: The imperative to invest in science has never been greater. J Clin Invest. 2014 Sep; 124(9):3680-1.
journal title abbreviation: J Clin Invest
publication date: 2014-09-02T00:00:00
year: 2014
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 563185
type: Authorship
author rank in publication: 7
linked author: Seidman, Christine
linked information resource: A gene for hereditary haemorrhagic telangiectasia maps to chromosome 9q3.

Authorship 345816
type: Authorship
author rank in publication: 12
linked author: Seidman, Christine
linked information resource: Missense mutations in the rod domain of the lamin A/C gene as causes of dilated cardiomyopathy and conduction-system disease.

Authorship 760243
type: Authorship
author rank in publication: 13
linked author: Seidman, Christine
linked information resource: Nationwide study on hypertrophic cardiomyopathy in Iceland: evidence of a MYBPC3 founder mutation.

Authorship 433281
type: Authorship
author rank in publication: 5
linked author: Seidman, Christine
linked information resource: Atrial natriuretic factor: assessment of its structure in atria and regulation of its biosynthesis with volume depletion.

Authorship 765197
type: Authorship
author rank in publication: 24
linked author: Seidman, Christine
linked information resource: Increased frequency of de novo copy number variants in congenital heart disease by integrative analysis of single nucleotide polymorphism array and exome sequence data.

Authorship 765391
type: Authorship
author rank in publication: 6
linked author: Seidman, Christine
linked information resource: Tbx5 is required for avian and Mammalian epicardial formation and coronary vasculogenesis.

Tbx5 is required for avian and Mammalian epicardial formation and coronary vasculogenesis.
PubMed Identifier: 25245104
author list: Diman NY, Brooks G, Kruithof BP, Elemento O, Seidman JG, Seidman CE, Basson CT, Hatcher CJ
published in: Circulation research
information resource reference: Tbx5 is required for avian and Mammalian epicardial formation and coronary vasculogenesis. Circ Res. 2014 Oct 24; 115(10):834-44.
journal title abbreviation: Circ Res
publication date: 2014-09-22T00:00:00
year: 2014
type: Academic Article
type: Article
type: Document
type: Information Resource

Increased frequency of de novo copy number variants in congenital heart disease by integrative analysis of single nucleotide polymorphism array and exome sequence data.
PubMed Identifier: 25205790
author list: Glessner JT, Bick AG, Ito K, Homsy J, Rodriguez-Murillo L, Fromer M, Mazaika E, Vardarajan B, Italia M, Leipzig J, DePalma SR, Golhar R, Sanders SJ, Yamrom B, Ronemus M, Iossifov I, Willsey AJ, State MW, Kaltman JR, White PS, Shen Y, Warburton D, Brueckner M, Seidman C, Goldmuntz E, Gelb BD, Lifton R, Seidman J, Hakonarson H, Chung WK
published in: Circulation research
information resource reference: Increased frequency of de novo copy number variants in congenital heart disease by integrative analysis of single nucleotide polymorphism array and exome sequence data. Circ Res. 2014 Oct 24; 115(10):884-896.
journal title abbreviation: Circ Res
publication date: 2014-09-09T00:00:00
year: 2014
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 767753
type: Authorship
author rank in publication: 13
linked author: Seidman, Christine
linked information resource: The imperative to invest in science has never been greater.

The imperative to invest in science has never been greater.
PubMed Identifier: 25365077
author list: Carethers JM, Coughlin S, Diamond B, Erzurum S, Fried LP, Jameson JL, Kaushansky K, Klotman ME, Lemon S, Mitchell B, Rothman P, Sawyers C, Seidman C, Somlo S
published in: The Journal of clinical investigation
information resource reference: The imperative to invest in science has never been greater. J Clin Invest. 2014 Nov 3; 124(11):5085.
journal title abbreviation: J Clin Invest
publication date: 2014-11-03T00:00:00
year: 2014
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 469923
type: Authorship
author rank in publication: 11
linked author: Seidman, Christine
linked information resource: Subtle abnormalities in contractile function are an early manifestation of sarcomere mutations in dilated cardiomyopathy.

Authorship 770398
type: Authorship
author rank in publication: 15
linked author: Seidman, Christine
linked information resource: Prediction of sarcomere mutations in subclinical hypertrophic cardiomyopathy.

Prediction of sarcomere mutations in subclinical hypertrophic cardiomyopathy.
PubMed Identifier: 25228707
author list: Captur G, Lopes LR, Mohun TJ, Patel V, Li C, Bassett P, Finocchiaro G, Ferreira VM, Esteban MT, Muthurangu V, Sherrid MV, Day SM, Canter CE, McKenna WJ, Seidman CE, Bluemke DA, Elliott PM, Ho CY, Moon JC
published in: Circulation. Cardiovascular imaging
information resource reference: Prediction of sarcomere mutations in subclinical hypertrophic cardiomyopathy. Circ Cardiovasc Imaging. 2014 Nov; 7(6):863-71.
journal title abbreviation: Circ Cardiovasc Imaging
publication date: 2014-09-16T00:00:00
year: 2014
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 364634
type: Authorship
author rank in publication: 8
linked author: Seidman, Christine
linked information resource: Independent origin of identical beta cardiac myosin heavy-chain mutations in hypertrophic cardiomyopathy.

Authorship 771254
type: Authorship
author rank in publication: 11
linked author: Seidman, Christine
linked information resource: Targeted and genome-wide sequencing reveal single nucleotide variations impacting specificity of Cas9 in human stem cells.

Targeted and genome-wide sequencing reveal single nucleotide variations impacting specificity of Cas9 in human stem cells.
PubMed Identifier: 25425480
author list: Yang L, Grishin D, Wang G, Aach J, Zhang CZ, Chari R, Homsy J, Cai X, Zhao Y, Fan JB, Seidman C, Seidman J, Pu W, Church G
published in: Nature communications
information resource reference: Targeted and genome-wide sequencing reveal single nucleotide variations impacting specificity of Cas9 in human stem cells. Nat Commun. 2014 Nov 26; 5:5507.
journal title abbreviation: Nat Commun
publication date: 2014-11-26T00:00:00
year: 2014
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 485453
type: Authorship
author rank in publication: 8
linked author: Seidman, Christine
linked information resource: https://connects.catalyst.harvard.edu/Profiles/profile/1037784

Authorship 502277
type: Authorship
author rank in publication: 2
linked author: Seidman, Christine
linked information resource: Effects of shrimp consumption on plasma lipoproteins.

Authorship 549606
type: Authorship
author rank in publication: 6
linked author: Seidman, Christine
linked information resource: Loss of function and inhibitory effects of human CSX/NKX2.5 homeoprotein mutations associated with congenital heart disease.

Authorship 488179
type: Authorship
author rank in publication: 14
linked author: Seidman, Christine
linked information resource: Polycomb repressive complex 2 regulates normal development of the mouse heart.

Authorship 778998
type: Authorship
author rank in publication: 5
linked author: Seidman, Christine
linked information resource: Merits and pitfalls of genetic testing in a hypertrophic cardiomyopathy clinic.

Merits and pitfalls of genetic testing in a hypertrophic cardiomyopathy clinic.
PubMed Identifier: 25558701
author list: Arad M, Monserrat L, Haron-Khun S, Seidman JG, Seidman CE, Arbustini E, Glikson M, Freimark D
published in: The Israel Medical Association journal : IMAJ
information resource reference: Merits and pitfalls of genetic testing in a hypertrophic cardiomyopathy clinic. Isr Med Assoc J. 2014 Nov; 16(11):707-13.
journal title abbreviation: Isr Med Assoc J
publication date: 2014-11-01T00:00:00
year: 2014
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 501617
type: Authorship
author rank in publication: 10
linked author: Seidman, Christine
linked information resource: Genome-wide identification of mouse congenital heart disease loci.

Authorship 510889
type: Authorship
author rank in publication: 21
linked author: Seidman, Christine
linked information resource: Research priorities in hypertrophic cardiomyopathy: report of a Working Group of the National Heart, Lung, and Blood Institute.

Authorship 565977
type: Authorship
author rank in publication: 11
linked author: Seidman, Christine
linked information resource: https://connects.catalyst.harvard.edu/Profiles/profile/957087

Authorship 572360
type: Authorship
author rank in publication: 8
linked author: Seidman, Christine
linked information resource: The clinical and genetic spectrum of the Holt-Oram syndrome (heart-hand syndrome)

Authorship 6185
type: Authorship
author rank in publication: 5
linked author: Seidman, Christine
linked information resource: Proatrial natriuretic factor is phosphorylated by rat cardiocytes in culture.

Authorship 71581
type: Authorship
author rank in publication: 4
linked author: Seidman, Christine
linked information resource: Pyogenic arthritis, pyoderma gangrenosum, and acne syndrome maps to chromosome 15q.

Authorship 74849
type: Authorship
author rank in publication: 7
linked author: Seidman, Christine
linked information resource: Hypertrophic and dilated cardiomyopathy mutations differentially affect the molecular force generation of mouse alpha-cardiac myosin in the laser trap assay.

Authorship 30248
type: Authorship
author rank in publication: 17
linked author: Seidman, Christine
linked information resource: Genome-wide association study identifies a susceptibility locus for thoracic aortic aneurysms and aortic dissections spanning FBN1 at 15q21.1.

Authorship 531061
type: Authorship
author rank in publication: 7
linked author: Seidman, Christine
linked information resource: Development of left ventricular hypertrophy in adults in hypertrophic cardiomyopathy caused by cardiac myosin-binding protein C gene mutations.

Authorship 401444
type: Authorship
author rank in publication: 6
linked author: Seidman, Christine
linked information resource: A polymorphic modifier gene alters the hypertrophic response in a murine model of familial hypertrophic cardiomyopathy.

Authorship 540956
type: Authorship
author rank in publication: 3
linked author: Seidman, Christine
linked information resource: https://connects.catalyst.harvard.edu/Profiles/profile/894755

Authorship 575736
type: Authorship
author rank in publication: 6
linked author: Seidman, Christine
linked information resource: Pheochromocytoma-induced cardiomyopathy is modulated by the synergistic effects of cell-secreted factors.

NKX2-5 mutations in an inbred consanguineous population: genetic and phenotypic diversity.
PubMed Identifier: 25742962
author list: Abou Hassan OK, Fahed AC, Batrawi M, Arabi M, Refaat MM, DePalma SR, Seidman JG, Seidman CE, Bitar FF, Nemer GM
published in: Scientific reports
information resource reference: NKX2-5 mutations in an inbred consanguineous population: genetic and phenotypic diversity. Sci Rep. 2015 Mar 06; 5:8848.
journal title abbreviation: Sci Rep
publication date: 2015-03-06T00:00:00
year: 2015
type: Academic Article
type: Article
type: Document
type: Information Resource

A systematic approach to the reporting of medically relevant findings from whole genome sequencing.
PubMed Identifier: 25714468
author list: McLaughlin HM, Ceyhan-Birsoy O, Christensen KD, Kohane IS, Krier J, Lane WJ, Lautenbach D, Lebo MS, Machini K, MacRae CA, Azzariti DR, Murray MF, Seidman CE, Vassy JL, Green RC, Rehm HL
published in: BMC medical genetics
information resource reference: A systematic approach to the reporting of medically relevant findings from whole genome sequencing. BMC Med Genet. 2014 Dec 14; 15:134.
journal title abbreviation: BMC Med Genet
publication date: 2014-12-14T00:00:00
year: 2014
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 9840
type: Authorship
author rank in publication: 7
linked author: Seidman, Christine
linked information resource: Electrophysiologic characteristics of accessory atrioventricular connections in an inherited form of Wolff-Parkinson-White syndrome.

Authorship 416749
type: Authorship
author rank in publication: 8
linked author: Seidman, Christine
linked information resource: Ca2+ dysregulation in Ryr1(I4895T/wt) mice causes congenital myopathy with progressive formation of minicores, cores, and nemaline rods.

Authorship 422377
type: Authorship
author rank in publication: 4
linked author: Seidman, Christine
linked information resource: Hereditary inclusion body myopathy maps to chromosome 9p1-q1.

Authorship 429033
type: Authorship
author rank in publication: 13
linked author: Seidman, Christine
linked information resource: Dilated cardiomyopathy and sensorineural hearing loss: a heritable syndrome that maps to 6q23-24.

Authorship 442554
type: Authorship
author rank in publication: 15
linked author: Seidman, Christine
linked information resource: Short communication: the cardiac myosin binding protein C Arg502Trp mutation: a common cause of hypertrophic cardiomyopathy.

Authorship 421344
type: Authorship
author rank in publication: 3
linked author: Seidman, Christine
linked information resource: Relationship between carbohydrate-induced hypertriglyceridemia and fatty acid synthesis in lean and obese subjects.

Authorship 337470
type: Authorship
author rank in publication: 15
linked author: Seidman, Christine
linked information resource: Dissection of chromosome 18 blood pressure and salt-sensitivity quantitative trait loci in the spontaneously hypertensive rat.

Authorship 355524
type: Authorship
author rank in publication: 6
linked author: Seidman, Christine
linked information resource: A dominant Stargardt's macular dystrophy locus maps to chromosome 13q34.

Authorship 498580
type: Authorship
author rank in publication: 4
linked author: Seidman, Christine
linked information resource: Cloning and functional characterization of extracellular Ca(2+)-sensing receptors from parathyroid and kidney.

Authorship 456773
type: Authorship
author rank in publication: 3
linked author: Seidman, Christine
linked information resource: Genetic causes of human heart failure.

Authorship 234092
type: Authorship
author rank in publication: 4
linked author: Seidman, Christine
linked information resource: QT dispersion in alpha-myosin heavy-chain familial hypertrophic cardiomyopathy mice.

Authorship 493243
type: Authorship
author rank in publication: 8
linked author: Seidman, Christine
linked information resource: Prevention of ventricular arrhythmia and calcium dysregulation in a catecholaminergic polymorphic ventricular tachycardia mouse model carrying calsequestrin-2 mutation.

Authorship 226408
type: Authorship
author rank in publication: 5
linked author: Seidman, Christine
linked information resource: Sequencing of TGF-beta pathway genes in familial cases of intracranial aneurysm.

Authorship 175594
type: Authorship
author rank in publication: 15
linked author: Seidman, Christine
linked information resource: Heterozygosity for a loss-of-function mutation in GALNT2 improves plasma triglyceride clearance in man.

Authorship 187777
type: Authorship
author rank in publication: 8
linked author: Seidman, Christine
linked information resource: An abnormal Ca(2+) response in mutant sarcomere protein-mediated familial hypertrophic cardiomyopathy.

Authorship 169996
type: Authorship
author rank in publication: 7
linked author: Seidman, Christine
linked information resource: Left ventricular hypertrophy and morphology in familial hypertrophic cardiomyopathy associated with mutations of the beta-myosin heavy chain gene.

Authorship 192729
type: Authorship
author rank in publication: 5
linked author: Seidman, Christine
linked information resource: Various types of hereditary inclusion body myopathies map to chromosome 9p1-q1.

Authorship 535037
type: Authorship
author rank in publication: 10
linked author: Seidman, Christine
linked information resource: Cloning, expression, and chromosomal location of SHH and IHH: two human homologues of the Drosophila segment polarity gene hedgehog.

Authorship 452528
type: Authorship
author rank in publication: 3
linked author: Seidman, Christine
linked information resource: In memorium.

Authorship 552484
type: Authorship
author rank in publication: 6
linked author: Seidman, Christine
linked information resource: A mouse model of familial hypertrophic cardiomyopathy.

Authorship 506011
type: Authorship
author rank in publication: 8
linked author: Seidman, Christine
linked information resource: Preclinical diagnosis of familial hypertrophic cardiomyopathy by genetic analysis of blood lymphocytes.

Authorship 519028
type: Authorship
author rank in publication: 17
linked author: Seidman, Christine
linked information resource: The role of cardiac troponin T quantity and function in cardiac development and dilated cardiomyopathy.

Authorship 569122
type: Authorship
author rank in publication: 18
linked author: Seidman, Christine
linked information resource: Cardiac fibrosis in mice with hypertrophic cardiomyopathy is mediated by non-myocyte proliferation and requires Tgf-ß.

Authorship 242477
type: Authorship
author rank in publication: 2
linked author: Seidman, Christine
linked information resource: Contemporary evaluation and management of hypertrophic cardiomyopathy.

Authorship 180608
type: Authorship
author rank in publication: 9
linked author: Seidman, Christine
linked information resource: Calsequestrin 2 (CASQ2) mutations increase expression of calreticulin and ryanodine receptors, causing catecholaminergic polymorphic ventricular tachycardia.

Authorship 329190
type: Authorship
author rank in publication: 1
linked author: Seidman, Christine
linked information resource: cis-dominance of rat atrial natriuretic factor gene regulatory sequences in transgenic mice.

Authorship 8188
type: Authorship
author rank in publication: 9
linked author: Seidman, Christine
linked information resource: Clinical features of hypertrophic cardiomyopathy caused by mutation of a "hot spot" in the alpha-tropomyosin gene.

Authorship 98979
type: Authorship
author rank in publication: 6
linked author: Seidman, Christine
linked information resource: A molecular basis for familial hypertrophic cardiomyopathy: a beta cardiac myosin heavy chain gene missense mutation.

Authorship 71320
type: Authorship
author rank in publication: 1
linked author: Seidman, Christine
linked information resource: Molecular genetic studies of familial hypertrophic cardiomyopathy.

Authorship 95280
type: Authorship
author rank in publication: 3
linked author: Seidman, Christine
linked information resource: Functional analysis of myosin missense mutations in familial hypertrophic cardiomyopathy.

Using next-generation RNA sequencing to examine ischemic changes induced by cold blood cardioplegia on the human left ventricular myocardium transcriptome.
PubMed Identifier: 25581909
author list: Muehlschlegel JD, Christodoulou DC, McKean D, Gorham J, Mazaika E, Heydarpour M, Lee G, DePalma SR, Perry TE, Fox AA, Shernan SK, Seidman CE, Aranki SF, Seidman JG, Body SC
published in: Anesthesiology
information resource reference: Using next-generation RNA sequencing to examine ischemic changes induced by cold blood cardioplegia on the human left ventricular myocardium transcriptome. Anesthesiology. 2015 Mar; 122(3):537-50.
journal title abbreviation: Anesthesiology
publication date: 2015-03-01T00:00:00
year: 2015
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 272385
type: Authorship
author rank in publication: 20
linked author: Seidman, Christine
linked information resource: Different TBX5 interactions in heart and limb defined by Holt-Oram syndrome mutations.

Authorship 239863
type: Authorship
author rank in publication: 6
linked author: Seidman, Christine
linked information resource: beta-Arrestin1 knockout mice appear normal but demonstrate altered cardiac responses to beta-adrenergic stimulation.

Authorship 379615
type: Authorship
author rank in publication: 7
linked author: Seidman, Christine
linked information resource: CLCN5 mutation Ser244Leu is associated with X-linked renal failure without X-linked recessive hypophosphatemic rickets.

Authorship 390649
type: Authorship
author rank in publication: 1
linked author: Seidman, Christine
linked information resource: Molecular studies of the atrial natriuretic factor gene.

Authorship 395556
type: Authorship
author rank in publication: 5
linked author: Seidman, Christine
linked information resource: Cardiac myosin binding protein-C is essential for thick-filament stability and flexural rigidity.

Authorship 262355
type: Authorship
author rank in publication: 11
linked author: Seidman, Christine
linked information resource: https://connects.catalyst.harvard.edu/Profiles/profile/952589

Authorship 296417
type: Authorship
author rank in publication: 9
linked author: Seidman, Christine
linked information resource: Tbx5-dependent rheostatic control of cardiac gene expression and morphogenesis.

Authorship 321084
type: Authorship
author rank in publication: 3
linked author: Seidman, Christine
linked information resource: Familial hypertrophic cardiomyopathy: a genetic model of cardiac hypertrophy.

Authorship 327600
type: Authorship
author rank in publication: 15
linked author: Seidman, Christine
linked information resource: Increased alpha2 subunit-associated AMPK activity and PRKAG2 cardiomyopathy.

Authorship 295377
type: Authorship
author rank in publication: 9
linked author: Seidman, Christine
linked information resource: Mutations in the cardiac myosin binding protein-C gene on chromosome 11 cause familial hypertrophic cardiomyopathy.

Authorship 304104
type: Authorship
author rank in publication: 4
linked author: Seidman, Christine
linked information resource: Functional effects of the TMEM43 Ser358Leu mutation in the pathogenesis of arrhythmogenic right ventricular cardiomyopathy.

Authorship 328571
type: Authorship
author rank in publication: 11
linked author: Seidman, Christine
linked information resource: Aberrant activation of AMP-activated protein kinase remodels metabolic network in favor of cardiac glycogen storage.

Authorship 343975
type: Authorship
author rank in publication: 17
linked author: Seidman, Christine
linked information resource: Genome-wide assessment for genetic variants associated with ventricular dysfunction after primary coronary artery bypass graft surgery.

Authorship 379061
type: Authorship
author rank in publication: 5
linked author: Seidman, Christine
linked information resource: Localized expression of the atrial natriuretic factor gene during cardiac embryogenesis.

Authorship 372296
type: Authorship
author rank in publication: 17
linked author: Seidman, Christine
linked information resource: Comparative proteomics profiling of a phospholamban mutant mouse model of dilated cardiomyopathy reveals progressive intracellular stress responses.

Authorship 401763
type: Authorship
author rank in publication: 2
linked author: Seidman, Christine
linked information resource: Three inherited disorders of calcium sensing.

Authorship 450502
type: Authorship
author rank in publication: 5
linked author: Seidman, Christine
linked information resource: Divergent pathways mediate the induction of ANF transgenes in neonatal and hypertrophic ventricular myocardium.

Authorship 128776
type: Authorship
author rank in publication: 8
linked author: Seidman, Christine
linked information resource: Myofilament mechanical performance is enhanced by R403Q myosin in mouse myocardium independent of sex.

Authorship 383939
type: Authorship
author rank in publication: 8
linked author: Seidman, Christine
linked information resource: Targeted ablation of the murine alpha-tropomyosin gene.

Authorship 213623
type: Authorship
author rank in publication: 9
linked author: Seidman, Christine
linked information resource: Reduced penetrance, variable expressivity, and genetic heterogeneity of familial atrial septal defects.

Authorship 56136
type: Authorship
author rank in publication: 12
linked author: Seidman, Christine
linked information resource: Familial dilated cardiomyopathy caused by an alpha-tropomyosin mutation: the distinctive natural history of sarcomeric dilated cardiomyopathy.

Authorship 60194
type: Authorship
author rank in publication: 9
linked author: Seidman, Christine
linked information resource: Altered hepatic transport of immunoglobulin A in mice lacking the J chain.

Authorship 60827
type: Authorship
author rank in publication: 10
linked author: Seidman, Christine
linked information resource: The gene responsible for familial hypocalciuric hypercalcemia maps to chromosome 3q in four unrelated families.

Authorship 246927
type: Authorship
author rank in publication: 19
linked author: Seidman, Christine
linked information resource: Dissecting spatio-temporal protein networks driving human heart development and related disorders.

Authorship 277972
type: Authorship
author rank in publication: 7
linked author: Seidman, Christine
linked information resource: Electrophysiologic characterization and postnatal development of ventricular pre-excitation in a mouse model of cardiac hypertrophy and Wolff-Parkinson-White syndrome.

Authorship 313614
type: Authorship
author rank in publication: 8
linked author: Seidman, Christine
linked information resource: Severe heart failure and early mortality in a double-mutation mouse model of familial hypertrophic cardiomyopathy.

Authorship 424934
type: Authorship
author rank in publication: 4
linked author: Seidman, Christine
linked information resource: Hypertrophic cardiomyopathy: translating cellular cross talk into therapeutics.

Authorship 432666
type: Authorship
author rank in publication: 3
linked author: Seidman, Christine
linked information resource: Altered cardiac excitation-contraction coupling in mutant mice with familial hypertrophic cardiomyopathy.

Authorship 147632
type: Authorship
author rank in publication: 1
linked author: Seidman, Christine
linked information resource: Synthesis and characterization of a radioiodinated photoaffinity probe for the alpha 1-adrenergic receptor.

Authorship 440081
type: Authorship
author rank in publication: 3
linked author: Seidman, Christine
linked information resource: [Using molecular genetics to guide the diagnosis and treatment of hypertrophic cardiomyopathy].

Authorship 208512
type: Authorship
author rank in publication: 9
linked author: Seidman, Christine
linked information resource: Ventricular arrhythmia vulnerability in cardiomyopathic mice with homozygous mutant Myosin-binding protein C gene.

Authorship 266588
type: Authorship
author rank in publication: 10
linked author: Seidman, Christine
linked information resource: Age-related autocrine diabetogenic effects of transgenic resistin in spontaneously hypertensive rats: gene expression profile analysis.

Authorship 450972
type: Authorship
author rank in publication: 3
linked author: Seidman, Christine
linked information resource: The metabolic and immunologic effects of short-term thalidomide treatment of patients infected with the human immunodeficiency virus.

Authorship 451929
type: Authorship
author rank in publication: 9
linked author: Seidman, Christine
linked information resource: Novel locus for an inherited cardiomyopathy maps to chromosome 7.

Authorship 22088
type: Authorship
author rank in publication: 7
linked author: Seidman, Christine
linked information resource: Sarcomere protein gene mutations in hypertrophic cardiomyopathy of the elderly.

Authorship 239585
type: Authorship
author rank in publication: 9
linked author: Seidman, Christine
linked information resource: Shared genetic causes of cardiac hypertrophy in children and adults.

Authorship 254315
type: Authorship
author rank in publication: 6
linked author: Seidman, Christine
linked information resource: A de novo mutation in alpha-tropomyosin that causes hypertrophic cardiomyopathy.

Authorship 258399
type: Authorship
author rank in publication: 8
linked author: Seidman, Christine
linked information resource: Autosomal dominant hypocalcaemia caused by a Ca(2+)-sensing receptor gene mutation.

Authorship 327552
type: Authorship
author rank in publication: 7
linked author: Seidman, Christine
linked information resource: Assessment of diastolic function with Doppler tissue imaging to predict genotype in preclinical hypertrophic cardiomyopathy.

Authorship 387688
type: Authorship
author rank in publication: 24
linked author: Seidman, Christine
linked information resource: De novo copy number variants identify new genes and loci in isolated sporadic tetralogy of Fallot.

Authorship 387825
type: Authorship
author rank in publication: 3
linked author: Seidman, Christine
linked information resource: https://connects.catalyst.harvard.edu/Profiles/profile/1000100

Authorship 417266
type: Authorship
author rank in publication: 10
linked author: Seidman, Christine
linked information resource: T cell responses in calcineurin A alpha-deficient mice.

Authorship 488583
type: Authorship
author rank in publication: 5
linked author: Seidman, Christine
linked information resource: https://connects.catalyst.harvard.edu/Profiles/profile/760483

Authorship 331123
type: Authorship
author rank in publication: 8
linked author: Seidman, Christine
linked information resource: Mutations in the human Ca(2+)-sensing receptor gene cause familial hypocalciuric hypercalcemia and neonatal severe hyperparathyroidism.

Authorship 381933
type: Authorship
author rank in publication: 7
linked author: Seidman, Christine
linked information resource: Chamber-specific cardiac expression of Tbx5 and heart defects in Holt-Oram syndrome.

Authorship 405655
type: Authorship
author rank in publication: 1
linked author: Seidman, Christine
linked information resource: Introduction of plasmid DNA into cells.

Authorship 504204
type: Authorship
author rank in publication: 10
linked author: Seidman, Christine
linked information resource: Role of cardiac myosin binding protein C in sustaining left ventricular systolic stiffening.

Authorship 574068
type: Authorship
author rank in publication: 7
linked author: Seidman, Christine
linked information resource: The PTPN11 gene is not implicated in nonsyndromic hypertrophic cardiomyopathy.

Authorship 793278
type: Authorship
author rank in publication: 15
linked author: Seidman, Christine
linked information resource: Diltiazem treatment for pre-clinical hypertrophic cardiomyopathy sarcomere mutation carriers: a pilot randomized trial to modify disease expression.

Authorship 795527
type: Authorship
author rank in publication: 41
linked author: Seidman, Christine
linked information resource: Integrated allelic, transcriptional, and phenomic dissection of the cardiac effects of titin truncations in health and disease.

Authorship 797692
type: Authorship
author rank in publication: 12
linked author: Seidman, Christine
linked information resource: Using next-generation RNA sequencing to examine ischemic changes induced by cold blood cardioplegia on the human left ventricular myocardium transcriptome.

Authorship 795398
type: Authorship
author rank in publication: 13
linked author: Seidman, Christine
linked information resource: A systematic approach to the reporting of medically relevant findings from whole genome sequencing.

Authorship 801309
type: Authorship
author rank in publication: 5
linked author: Seidman, Christine
linked information resource: A one-page summary report of genome sequencing for the healthy adult.

Authorship 804486
type: Authorship
author rank in publication: 8
linked author: Seidman, Christine
linked information resource: NKX2-5 mutations in an inbred consanguineous population: genetic and phenotypic diversity.

Authorship 799314
type: Authorship
author rank in publication: 5
linked author: Seidman, Christine
linked information resource: Haploinsufficiency of MYBPC3 exacerbates the development of hypertrophic cardiomyopathy in heterozygous mice.

A one-page summary report of genome sequencing for the healthy adult.
PubMed Identifier: 25612602
author list: Vassy JL, McLaughlin HM, McLaughlin HL, MacRae CA, Seidman CE, Lautenbach D, Krier JB, Lane WJ, Kohane IS, Murray MF, McGuire AL, Rehm HL, Green RC
published in: Public health genomics
information resource reference: A one-page summary report of genome sequencing for the healthy adult. Public Health Genomics. 2015; 18(2):123-9.
journal title abbreviation: Public Health Genomics
publication date: 2015-01-21T00:00:00
year: 2015
type: Academic Article
type: Article
type: Document
type: Information Resource

Diltiazem treatment for pre-clinical hypertrophic cardiomyopathy sarcomere mutation carriers: a pilot randomized trial to modify disease expression.
PubMed Identifier: 25543971
author list: Ho CY, Lakdawala NK, Cirino AL, Lipshultz SE, Sparks E, Abbasi SA, Kwong RY, Antman EM, Semsarian C, González A, López B, Diez J, Orav EJ, Colan SD, Seidman CE
published in: JACC. Heart failure
information resource reference: Diltiazem treatment for pre-clinical hypertrophic cardiomyopathy sarcomere mutation carriers: a pilot randomized trial to modify disease expression. JACC Heart Fail. 2015 Feb; 3(2):180-8.
journal title abbreviation: JACC Heart Fail
publication date: 2014-10-31T00:00:00
year: 2014
type: Academic Article
type: Article
type: Document
type: Information Resource

Haploinsufficiency of MYBPC3 exacerbates the development of hypertrophic cardiomyopathy in heterozygous mice.
PubMed Identifier: 25463273
author list: Barefield D, Kumar M, Gorham J, Seidman JG, Seidman CE, de Tombe PP, Sadayappan S
published in: Journal of molecular and cellular cardiology
information resource reference: Haploinsufficiency of MYBPC3 exacerbates the development of hypertrophic cardiomyopathy in heterozygous mice. J Mol Cell Cardiol. 2015 Feb; 79:234-43.
journal title abbreviation: J Mol Cell Cardiol
publication date: 2014-11-25T00:00:00
year: 2014
type: Academic Article
type: Article
type: Document
type: Information Resource

Integrated allelic, transcriptional, and phenomic dissection of the cardiac effects of titin truncations in health and disease.
PubMed Identifier: 25589632
author list: Roberts AM, Ware JS, Herman DS, Schafer S, Baksi J, Bick AG, Buchan RJ, Walsh R, John S, Wilkinson S, Mazzarotto F, Felkin LE, Gong S, MacArthur JA, Cunningham F, Flannick J, Gabriel SB, Altshuler DM, Macdonald PS, Heinig M, Keogh AM, Hayward CS, Banner NR, Pennell DJ, O'Regan DP, San TR, de Marvao A, Dawes TJ, Gulati A, Birks EJ, Yacoub MH, Radke M, Gotthardt M, Wilson JG, O'Donnell CJ, Prasad SK, Barton PJ, Fatkin D, Hubner N, Seidman JG, Seidman CE, Cook SA
published in: Science translational medicine
information resource reference: Integrated allelic, transcriptional, and phenomic dissection of the cardiac effects of titin truncations in health and disease. Sci Transl Med. 2015 Jan 14; 7(270):270ra6.
journal title abbreviation: Sci Transl Med
publication date: 2015-01-14T00:00:00
year: 2015
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 382213
type: Authorship
author rank in publication: 2
linked author: Seidman, Christine
linked information resource: The genetic basis for cardiomyopathy: from mutation identification to mechanistic paradigms.

Authorship 389085
type: Authorship
author rank in publication: 29
linked author: Seidman, Christine
linked information resource: Truncations of titin causing dilated cardiomyopathy.

Authorship 440819
type: Authorship
author rank in publication: 12
linked author: Seidman, Christine
linked information resource: Mutations in a novel cochlear gene cause DFNA9, a human nonsyndromic deafness with vestibular dysfunction.

Authorship 453637
type: Authorship
author rank in publication: 18
linked author: Seidman, Christine
linked information resource: Genetic testing for dilated cardiomyopathy in clinical practice.

Authorship 501122
type: Authorship
author rank in publication: 7
linked author: Seidman, Christine
linked information resource: Polony multiplex analysis of gene expression (PMAGE) in mouse hypertrophic cardiomyopathy.

Authorship 386369
type: Authorship
author rank in publication: 6
linked author: Seidman, Christine
linked information resource: Eya4-deficient mice are a model for heritable otitis media.

Authorship 412349
type: Authorship
author rank in publication: 7
linked author: Seidman, Christine
linked information resource: Effect of cardiac myosin binding protein-C on mechanoenergetics in mouse myocardium.

Authorship 808512
type: Authorship
author rank in publication: 15
linked author: Seidman, Christine
linked information resource: Phenotype and prognostic correlations of the converter region mutations affecting the ß myosin heavy chain.

Phenotype and prognostic correlations of the converter region mutations affecting the ß myosin heavy chain.
PubMed Identifier: 25935763
author list: García-Giustiniani D, Arad M, Ortíz-Genga M, Barriales-Villa R, Fernández X, Rodríguez-García I, Mazzanti A, Veira E, Maneiro E, Rebolo P, Lesende I, Cazón L, Freimark D, Gimeno-Blanes JR, Seidman C, Seidman J, McKenna W, Monserrat L
published in: Heart (British Cardiac Society)
information resource reference: Phenotype and prognostic correlations of the converter region mutations affecting the ß myosin heavy chain. Heart. 2015 Jul; 101(13):1047-53.
journal title abbreviation: Heart
publication date: 2015-05-02T00:00:00
year: 2015
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 303221
type: Authorship
author rank in publication: 10
linked author: Seidman, Christine
linked information resource: Haploinsufficiency of MSX1: a mechanism for selective tooth agenesis.

Authorship 317020
type: Authorship
author rank in publication: 3
linked author: Seidman, Christine
linked information resource: Calcium-ion-sensing cell-surface receptors.

Authorship 817091
type: Authorship
author rank in publication: 11
linked author: Seidman, Christine
linked information resource: Cardiac myosin binding protein C regulates postnatal myocyte cytokinesis.

Cardiac myosin binding protein C regulates postnatal myocyte cytokinesis.
PubMed Identifier: 26153423
author list: Jiang J, Burgon PG, Wakimoto H, Onoue K, Gorham JM, O'Meara CC, Fomovsky G, McConnell BK, Lee RT, Seidman JG, Seidman CE
published in: Proceedings of the National Academy of Sciences of the United States of America
information resource reference: Cardiac myosin binding protein C regulates postnatal myocyte cytokinesis. Proc Natl Acad Sci U S A. 2015 Jul 21; 112(29):9046-51.
journal title abbreviation: Proc Natl Acad Sci U S A
publication date: 2015-07-07T00:00:00
year: 2015
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 381301
type: Authorship
author rank in publication: 11
linked author: Seidman, Christine
linked information resource: Clinical and genetic linkage analysis of a large Venezuelan kindred with Usher syndrome.

Authorship 383795
type: Authorship
author rank in publication: 3
linked author: Seidman, Christine
linked information resource: The genetic basis for cardiac remodeling.

Authorship 431905
type: Authorship
author rank in publication: 8
linked author: Seidman, Christine
linked information resource: Consequences of pressure overload on sarcomere protein mutation-induced hypertrophic cardiomyopathy.

Authorship 501028
type: Authorship
author rank in publication: 4
linked author: Seidman, Christine
linked information resource: Reduced cross-bridge dependent stiffness of skinned myocardium from mice lacking cardiac myosin binding protein-C.

HEART DISEASE. Titin mutations in iPS cells define sarcomere insufficiency as a cause of dilated cardiomyopathy.
PubMed Identifier: 26315439
author list: Hinson JT, Chopra A, Nafissi N, Polacheck WJ, Benson CC, Swist S, Gorham J, Yang L, Schafer S, Sheng CC, Haghighi A, Homsy J, Hubner N, Church G, Cook SA, Linke WA, Chen CS, Seidman JG, Seidman CE
published in: Science (New York, N.Y.)
information resource reference: HEART DISEASE. Titin mutations in iPS cells define sarcomere insufficiency as a cause of dilated cardiomyopathy. Science. 2015 Aug 28; 349(6251):982-6.
journal title abbreviation: Science
publication date: 2015-08-28T00:00:00
year: 2015
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 831102
type: Authorship
author rank in publication: 19
linked author: Seidman, Christine
linked information resource: HEART DISEASE. Titin mutations in iPS cells define sarcomere insufficiency as a cause of dilated cardiomyopathy.

Authorship 561828
type: Authorship
author rank in publication: 6
linked author: Seidman, Christine
linked information resource: Differential cross-bridge kinetics of FHC myosin mutations R403Q and R453C in heterozygous mouse myocardium.

Authorship 64256
type: Authorship
author rank in publication: 7
linked author: Seidman, Christine
linked information resource: Increased glycogen stores due to gamma-AMPK overexpression protects against ischemia and reperfusion damage.

Authorship 78280
type: Authorship
author rank in publication: 4
linked author: Seidman, Christine
linked information resource: Genetics of hypertrophic cardiomyopathy.

Authorship 9747
type: Authorship
author rank in publication: 7
linked author: Seidman, Christine
linked information resource: Homozygosity mapping of the gene for alkaptonuria to chromosome 3q2.

Authorship 363099
type: Authorship
author rank in publication: 3
linked author: Seidman, Christine
linked information resource: Elevated rates of force development and MgATP binding in F764L and S532P myosin mutations causing dilated cardiomyopathy.

Authorship 42829
type: Authorship
author rank in publication: 5
linked author: Seidman, Christine
linked information resource: Connexin 40, a target of transcription factor Tbx5, patterns wrist, digits, and sternum.

Authorship 845756
type: Authorship
author rank in publication: 16
linked author: Seidman, Christine
linked information resource: Cardiomyocyte-enriched protein CIP protects against pathophysiological stresses and regulates cardiac homeostasis.

Cardiomyocyte-enriched protein CIP protects against pathophysiological stresses and regulates cardiac homeostasis.
PubMed Identifier: 26436652
author list: Huang ZP, Kataoka M, Chen J, Wu G, Ding J, Nie M, Lin Z, Liu J, Hu X, Ma L, Zhou B, Wakimoto H, Zeng C, Kyselovic J, Deng ZL, Seidman CE, Seidman JG, Pu WT, Wang DZ
published in: The Journal of clinical investigation
information resource reference: Cardiomyocyte-enriched protein CIP protects against pathophysiological stresses and regulates cardiac homeostasis. J Clin Invest. 2015 Nov 02; 125(11):4122-34.
journal title abbreviation: J Clin Invest
publication date: 2015-10-05T00:00:00
year: 2015
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 848845
type: Authorship
author rank in publication: 15
linked author: Seidman, Christine
linked information resource: Results of clinical genetic testing of 2,912 probands with hypertrophic cardiomyopathy: expanded panels offer limited additional sensitivity.

Results of clinical genetic testing of 2,912 probands with hypertrophic cardiomyopathy: expanded panels offer limited additional sensitivity.
PubMed Identifier: 25611685
author list: Alfares AA, Kelly MA, McDermott G, Funke BH, Lebo MS, Baxter SB, Shen J, McLaughlin HM, Clark EH, Babb LJ, Cox SW, DePalma SR, Ho CY, Seidman JG, Seidman CE, Rehm HL
published in: Genetics in medicine : official journal of the American College of Medical Genetics
information resource reference: Results of clinical genetic testing of 2,912 probands with hypertrophic cardiomyopathy: expanded panels offer limited additional sensitivity. Genet Med. 2015 Nov; 17(11):880-8.
journal title abbreviation: Genet Med
publication date: 2015-01-22T00:00:00
year: 2015
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 514246
type: Authorship
author rank in publication: 4
linked author: Seidman, Christine
linked information resource: A novel missense mutation in the paired domain of PAX9 causes non-syndromic oligodontia.

Authorship 521130
type: Authorship
author rank in publication: 6
linked author: Seidman, Christine
linked information resource: Cao-sensing receptor (CaR)-mediated activation of K+ channels is blunted in CaR gene-deficient mouse neurons.

Authorship 542649
type: Authorship
author rank in publication: 4
linked author: Seidman, Christine
linked information resource: A new autosomal dominant disorder of pyogenic sterile arthritis, pyoderma gangrenosum, and acne: PAPA syndrome.

Authorship 548921
type: Authorship
author rank in publication: 11
linked author: Seidman, Christine
linked information resource: Mutations in the cardiac transcription factor NKX2.5 affect diverse cardiac developmental pathways.

Authorship 858428
type: Authorship
author rank in publication: 40
linked author: Seidman, Christine
linked information resource: De novo mutations in congenital heart disease with neurodevelopmental and other congenital anomalies.

Authorship 858626
type: Authorship
author rank in publication: 33
linked author: Seidman, Christine
linked information resource: Shared Genetic Predisposition in Peripartum and Dilated Cardiomyopathies.

Shared Genetic Predisposition in Peripartum and Dilated Cardiomyopathies.
PubMed Identifier: 26735901
author list: Ware JS, Li J, Mazaika E, Yasso CM, DeSouza T, Cappola TP, Tsai EJ, Hilfiker-Kleiner D, Kamiya CA, Mazzarotto F, Cook SA, Halder I, Prasad SK, Pisarcik J, Hanley-Yanez K, Alharethi R, Damp J, Hsich E, Elkayam U, Sheppard R, Kealey A, Alexis J, Ramani G, Safirstein J, Boehmer J, Pauly DF, Wittstein IS, Thohan V, Zucker MJ, Liu P, Gorcsan J, McNamara DM, Seidman CE, Seidman JG, Arany Z
published in: The New England journal of medicine
information resource reference: Shared Genetic Predisposition in Peripartum and Dilated Cardiomyopathies. N Engl J Med. 2016 Jan 21; 374(3):233-41.
journal title abbreviation: N Engl J Med
publication date: 2016-01-06T00:00:00
year: 2016
type: Academic Article
type: Article
type: Document
type: Information Resource

De novo mutations in congenital heart disease with neurodevelopmental and other congenital anomalies.
PubMed Identifier: 26785492
author list: Homsy J, Zaidi S, Shen Y, Ware JS, Samocha KE, Karczewski KJ, DePalma SR, McKean D, Wakimoto H, Gorham J, Jin SC, Deanfield J, Giardini A, Porter GA, Kim R, Bilguvar K, López-Giráldez F, Tikhonova I, Mane S, Romano-Adesman A, Qi H, Vardarajan B, Ma L, Daly M, Roberts AE, Russell MW, Mital S, Newburger JW, Gaynor JW, Breitbart RE, Iossifov I, Ronemus M, Sanders SJ, Kaltman JR, Seidman JG, Brueckner M, Gelb BD, Goldmuntz E, Lifton RP, Seidman CE, Chung WK
published in: Science (New York, N.Y.)
information resource reference: De novo mutations in congenital heart disease with neurodevelopmental and other congenital anomalies. Science. 2015 Dec 04; 350(6265):1262-6.
journal title abbreviation: Science
publication date: 2015-12-04T00:00:00
year: 2015
type: Academic Article
type: Article
type: Document
type: Information Resource

The Muscle-Bound Heart.
PubMed Identifier: 26920199
author list: Refaat MM, Fahed AC, Hassanieh S, Hotait M, Arabi M, Skouri H, Seidman JG, Seidman CE, Bitar FF, Nemer G
published in: Cardiac electrophysiology clinics
information resource reference: The Muscle-Bound Heart. Card Electrophysiol Clin. 2016 Mar; 8(1):223-31.
journal title abbreviation: Card Electrophysiol Clin
publication date: 2016-03-01T00:00:00
year: 2016
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 86449
type: Authorship
author rank in publication: 9
linked author: Seidman, Christine
linked information resource: An alpha-cardiac myosin heavy chain gene mutation impairs contraction and relaxation function of cardiac myocytes.

Authorship 863763
type: Authorship
author rank in publication: 15
linked author: Seidman, Christine
linked information resource: CORRIGENDUM: Results of clinical genetic testing of 2,912 probands with hypertrophic cardiomyopathy: expanded panels offer limited additional sensitivity.

Authorship 869998
type: Authorship
author rank in publication: 17
linked author: Seidman, Christine
linked information resource: A small-molecule inhibitor of sarcomere contractility suppresses hypertrophic cardiomyopathy in mice.

Authorship 869564
type: Authorship
author rank in publication: 8
linked author: Seidman, Christine
linked information resource: The Muscle-Bound Heart.

Authorship 867373
type: Authorship
author rank in publication: 5
linked author: Seidman, Christine
linked information resource: Mutation analysis of the phospholamban gene in 315 South Africans with dilated, hypertrophic, peripartum and arrhythmogenic right ventricular cardiomyopathies.

A small-molecule inhibitor of sarcomere contractility suppresses hypertrophic cardiomyopathy in mice.
PubMed Identifier: 26912705
author list: Green EM, Wakimoto H, Anderson RL, Evanchik MJ, Gorham JM, Harrison BC, Henze M, Kawas R, Oslob JD, Rodriguez HM, Song Y, Wan W, Leinwand LA, Spudich JA, McDowell RS, Seidman JG, Seidman CE
published in: Science (New York, N.Y.)
information resource reference: A small-molecule inhibitor of sarcomere contractility suppresses hypertrophic cardiomyopathy in mice. Science. 2016 Feb 05; 351(6273):617-21.
journal title abbreviation: Science
publication date: 2016-02-05T00:00:00
year: 2016
type: Academic Article
type: Article
type: Document
type: Information Resource

Mutation analysis of the phospholamban gene in 315 South Africans with dilated, hypertrophic, peripartum and arrhythmogenic right ventricular cardiomyopathies.
PubMed Identifier: 26917049
author list: Fish M, Shaboodien G, Kraus S, Sliwa K, Seidman CE, Burke MA, Crotti L, Schwartz PJ, Mayosi BM
published in: Scientific reports
information resource reference: Mutation analysis of the phospholamban gene in 315 South Africans with dilated, hypertrophic, peripartum and arrhythmogenic right ventricular cardiomyopathies. Sci Rep. 2016 Feb 26; 6:22235.
journal title abbreviation: Sci Rep
publication date: 2016-02-26T00:00:00
year: 2016
type: Academic Article
type: Article
type: Document
type: Information Resource

CORRIGENDUM: Results of clinical genetic testing of 2,912 probands with hypertrophic cardiomyopathy: expanded panels offer limited additional sensitivity.
PubMed Identifier: 25835197
author list: Alfares AA, Kelly MA, McDermott G, Funke BH, Lebo MS, Baxter SB, Shen J, McLaughlin HM, Clark EH, Babb LJ, Cox SW, DePalma SR, Ho CY, Seidman JG, Seidman CE, Rehm HL
published in: Genetics in medicine : official journal of the American College of Medical Genetics
information resource reference: CORRIGENDUM: Results of clinical genetic testing of 2,912 probands with hypertrophic cardiomyopathy: expanded panels offer limited additional sensitivity. Genet Med. 2015 Apr; 17(4):319.
journal title abbreviation: Genet Med
publication date: 2015-04-01T00:00:00
year: 2015
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 95258
type: Authorship
author rank in publication: 6
linked author: Seidman, Christine
linked information resource: Amyloid-beta proteins activate Ca(2+)-permeable channels through calcium-sensing receptors.

Authorship 98166
type: Authorship
author rank in publication: 10
linked author: Seidman, Christine
linked information resource: Glycogen storage diseases presenting as hypertrophic cardiomyopathy.

Authorship 94262
type: Authorship
author rank in publication: 2
linked author: Seidman, Christine
linked information resource: The management of hypertrophic cardiomyopathy.

Authorship 340982
type: Authorship
author rank in publication: 4
linked author: Seidman, Christine
linked information resource: Alcohol consumption raises HDL cholesterol levels by increasing the transport rate of apolipoproteins A-I and A-II.

Authorship 183587
type: Authorship
author rank in publication: 7
linked author: Seidman, Christine
linked information resource: Heritable cardiac conduction and myocardial disease: from the clinic to the basic science laboratory and back to the clinic.

Authorship 383682
type: Authorship
author rank in publication: 2
linked author: Seidman, Christine
linked information resource: AMP-activated protein kinase in the heart: role during health and disease.

Authorship 465030
type: Authorship
author rank in publication: 4
linked author: Seidman, Christine
linked information resource: Characterization of endoglin and identification of novel mutations in hereditary hemorrhagic telangiectasia.

Authorship 470598
type: Authorship
author rank in publication: 4
linked author: Seidman, Christine
linked information resource: Regulation of chamber-specific gene expression in the developing heart by Irx4.

Authorship 50818
type: Authorship
author rank in publication: 5
linked author: Seidman, Christine
linked information resource: A dinucleotide repeat polymorphism in the human LAMB2 gene on chromosome 1q.

Authorship 882607
type: Authorship
author rank in publication: 5
linked author: Seidman, Christine
linked information resource: Corrigendum: Mutation analysis of the phospholamban gene in 315 South Africans with dilated, hypertrophic, peripartum and arrhythmogenic right ventricular cardiomyopathies.

Corrigendum: Mutation analysis of the phospholamban gene in 315 South Africans with dilated, hypertrophic, peripartum and arrhythmogenic right ventricular cardiomyopathies.
PubMed Identifier: 27189347
author list: Fish M, Shaboodien G, Kraus S, Sliwa K, Seidman CE, Burke MA, Crotti L, Schwartz PJ, Mayosi BM
published in: Scientific reports
information resource reference: Corrigendum: Mutation analysis of the phospholamban gene in 315 South Africans with dilated, hypertrophic, peripartum and arrhythmogenic right ventricular cardiomyopathies. Sci Rep. 2016 05 18; 6:25863.
journal title abbreviation: Sci Rep
publication date: 2016-05-18T00:00:00
year: 2016
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 532229
type: Authorship
author rank in publication: 9
linked author: Seidman, Christine
linked information resource: The T-Box transcription factor Tbx5 is required for the patterning and maturation of the murine cardiac conduction system.

Authorship 883228
type: Authorship
author rank in publication: 11
linked author: Seidman, Christine
linked information resource: A Tension-Based Model Distinguishes Hypertrophic versus Dilated Cardiomyopathy.

A Tension-Based Model Distinguishes Hypertrophic versus Dilated Cardiomyopathy.
PubMed Identifier: 27114035
author list: Davis J, Davis LC, Correll RN, Makarewich CA, Schwanekamp JA, Moussavi-Harami F, Wang D, York AJ, Wu H, Houser SR, Seidman CE, Seidman JG, Regnier M, Metzger JM, Wu JC, Molkentin JD
published in: Cell
information resource reference: A Tension-Based Model Distinguishes Hypertrophic versus Dilated Cardiomyopathy. Cell. 2016 May 19; 165(5):1147-1159.
journal title abbreviation: Cell
publication date: 2016-04-21T00:00:00
year: 2016
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 550478
type: Authorship
author rank in publication: 6
linked author: Seidman, Christine
linked information resource: Missense mutation in the pore region of HERG causes familial long QT syndrome.

Authorship 563466
type: Authorship
author rank in publication: 4
linked author: Seidman, Christine
linked information resource: Ouabain induces secretion of proatrial natriuretic factor by rat atrial cardiocytes.

Authorship 574956
type: Authorship
author rank in publication: 8
linked author: Seidman, Christine
linked information resource: CD36 overexpression predisposes to arrhythmias but reduces infarct size in spontaneously hypertensive rats: gene expression profile analysis.

Authorship 569822
type: Authorship
author rank in publication: 10
linked author: Seidman, Christine
linked information resource: A murine model of Holt-Oram syndrome defines roles of the T-box transcription factor Tbx5 in cardiogenesis and disease.

Assistant Professor
sort order: 2
type: Faculty Rank

Associate Professor
sort order: 1
type: Faculty Rank

Full Professor
sort order: 0
type: Faculty Rank

Instructor
sort order: 4
type: Faculty Rank

Authorship 890547
type: Authorship
author rank in publication: 3
linked author: Seidman, Christine
linked information resource: Detection of Cell Proliferation Markers by Immunofluorescence Staining and Microscopy Imaging in Paraffin-Embedded Tissue Sections.

Detection of Cell Proliferation Markers by Immunofluorescence Staining and Microscopy Imaging in Paraffin-Embedded Tissue Sections.
PubMed Identifier: 27366888
author list: Eminaga S, Teekakirikul P, Seidman CE, Seidman JG
published in: Current protocols in molecular biology
information resource reference: Detection of Cell Proliferation Markers by Immunofluorescence Staining and Microscopy Imaging in Paraffin-Embedded Tissue Sections. Curr Protoc Mol Biol. 2016 07 01; 115:14.25.1-14.25.14.
journal title abbreviation: Curr Protoc Mol Biol
publication date: 2016-07-01T00:00:00
year: 2016
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 499868
type: Authorship
author rank in publication: 5
linked author: Seidman, Christine
linked information resource: Familial hypertrophic cardiomyopathy mice display gender differences in electrophysiological abnormalities.

Authorship 536621
type: Authorship
author rank in publication: 6
linked author: Seidman, Christine
linked information resource: A nonsense mutation in MSX1 causes Witkop syndrome.

Authorship 551622
type: Authorship
author rank in publication: 19
linked author: Seidman, Christine
linked information resource: https://connects.catalyst.harvard.edu/Profiles/profile/1105934

Authorship 897033
type: Authorship
author rank in publication: 4
linked author: Seidman, Christine
linked information resource: Transcriptional Profiling of Cultured, Embryonic Epicardial Cells Identifies Novel Genes and Signaling Pathways Regulated by TGFßR3 In Vitro.

Transcriptional Profiling of Cultured, Embryonic Epicardial Cells Identifies Novel Genes and Signaling Pathways Regulated by TGFßR3 In Vitro.
PubMed Identifier: 27505173
author list: DeLaughter DM, Clark CR, Christodoulou DC, Seidman CE, Baldwin HS, Seidman JG, Barnett JV
published in: PloS one
information resource reference: Transcriptional Profiling of Cultured, Embryonic Epicardial Cells Identifies Novel Genes and Signaling Pathways Regulated by TGFßR3 In Vitro. PLoS One. 2016; 11(8):e0159710.
journal title abbreviation: PLoS One
publication date: 2016-08-09T00:00:00
year: 2016
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 89631
type: Authorship
author rank in publication: 12
linked author: Seidman, Christine
linked information resource: Myocardial fibrosis as an early manifestation of hypertrophic cardiomyopathy.

Authorship 476732
type: Authorship
author rank in publication: 8
linked author: Seidman, Christine
linked information resource: Genetic analysis of susceptibility to experimental autoimmune encephalomyelitis in a cross between SJL/J and B10.S mice.

Authorship 907895
type: Authorship
author rank in publication: 4
linked author: Seidman, Christine
linked information resource: Reduced cross-bridge dependent stiffness of skinned myocardium from mice lacking cardiac myosin binding protein-C.

Reduced cross-bridge dependent stiffness of skinned myocardium from mice lacking cardiac myosin binding protein-C.
PubMed Identifier: 27520666
author list: Palmer BM, McConnell BK, Li GH, Seidman CE, Seidman JG, Irving TC, Alpert NR, Maughan DW
published in: Molecular and cellular biochemistry
information resource reference: Reduced cross-bridge dependent stiffness of skinned myocardium from mice lacking cardiac myosin binding protein-C. Mol Cell Biochem. 2004 Aug; 263(1):73-80.
journal title abbreviation: Mol Cell Biochem
publication date: 2004-08-01T00:00:00
year: 2004
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 522993
type: Authorship
author rank in publication: 8
linked author: Seidman, Christine
linked information resource: Mutations of TTN, encoding the giant muscle filament titin, cause familial dilated cardiomyopathy.

Authorship 909452
type: Authorship
author rank in publication: 13
linked author: Seidman, Christine
linked information resource: Pitx2 modulates a Tbx5-dependent gene regulatory network to maintain atrial rhythm.

Pitx2 modulates a Tbx5-dependent gene regulatory network to maintain atrial rhythm.
PubMed Identifier: 27582060
author list: Nadadur RD, Broman MT, Boukens B, Mazurek SR, Yang X, van den Boogaard M, Bekeny J, Gadek M, Ward T, Zhang M, Qiao Y, Martin JF, Seidman CE, Seidman J, Christoffels V, Efimov IR, McNally EM, Weber CR, Moskowitz IP
published in: Science translational medicine
information resource reference: Pitx2 modulates a Tbx5-dependent gene regulatory network to maintain atrial rhythm. Sci Transl Med. 2016 08 31; 8(354):354ra115.
journal title abbreviation: Sci Transl Med
publication date: 2016-08-31T00:00:00
year: 2016
type: Academic Article
type: Article
type: Document
type: Information Resource

The Genomic Basis of Congenital Heart Disease and Neurodevelopmental Outcomes
end date: 2020-07-31
principal investigator name: NEWBURGER, JANE W.
start date: 2009-09-30
type: Grant
sponsor award id: UM1HL098147

GENETIC ANALYSIS OF FAMILIAL HYPERTROPHIC CARDIOMYOPATHY
end date: 1995-03-31
principal investigator name: SEIDMAN, CHRISTINE E.
start date: 1990-01-01
type: Grant
sponsor award id: R01HL042467

SPECIALIZED CENTER OF RESEARCH IN HEART FAILURE
end date: 2006-01-31
principal investigator name: SEIDMAN, CHRISTINE E.
start date: 1995-01-15
type: Grant
sponsor award id: P50HL052320

DIGITAILS--MECHANISM AND REVERSAL STUDIES
end date: 1999-08-31
principal investigator name: SMITH, THOMAS W
start date: 1985-09-01
type: Grant
sponsor award id: R37HL036141

Regulation of Cardiac Development in Health and Disease
end date: 2020-10-31
principal investigator name: SEIDMAN, JONATHAN G
start date: 2009-09-30
type: Grant
sponsor award id: UM1HL098166

Defining Genetic Architecture and Pathways of DCM
end date: 2025-01-31
principal investigator name: SEIDMAN, JONATHAN G
start date: 2005-04-01
type: Grant
sponsor award id: R01HL080494

Using Genetics for Early Phenotyping &Prevention of Hypertrophic Cardiomyopathy
end date: 2013-03-31
principal investigator name: HO, CAROLYN Y
start date: 2010-04-01
type: Grant
sponsor award id: P20HL101408

Genomic Effects on Right Ventricular Function, Clinical Features and Outcomes in CHD
end date: 2025-07-31
principal investigator name: NEWBURGER, JANE W.
start date: 2009-09-30
type: Grant
sponsor award id: U01HL098147

MOLECULAR MECHANISMS OF CONGENITAL HEART DISEASE
end date: 2004-03-31
principal investigator name: IZUMO, SEIGO
start date: 1999-01-01
type: Grant
sponsor award id: P50HL061036

GENETICS OF FAMILIAL HYPOCALCIURIC HYPERCALCEMIA
end date: 1998-04-30
principal investigator name: SEIDMAN, CHRISTINE E.
start date: 1993-05-01
type: Grant
sponsor award id: R01DK046422

Using Genetics For Early Phenotyping & Prevention of Hypertrophic Cardiomyopathy
end date: 2021-07-31
principal investigator name: HO, CAROLYN Y
start date: 2012-05-15
type: Grant
sponsor award id: P50HL112349

DIGITAILS--MECHANISM AND REVERSAL STUDIES
end date: 2000-08-31
principal investigator name: KELLY, RALPH A
start date: 1985-09-01
type: Grant
sponsor award id: R01HL036141

SSCOR in Pediatric Heart Development and Disease
end date: 2010-01-31
principal investigator name: NEWBURGER, JANE W.
start date: 2004-02-15
type: Grant
sponsor award id: P50HL074734

DEVELOPMENT OF STABLE CARDIAC CELL LINES
end date: 1993-06-30
principal investigator name: SEIDMAN, CHRISTINE E.
start date: 1988-07-01
type: Grant
sponsor award id: R29HL041474

SHORT-TERM TRAINING IN HEALTH PROFESSIONAL SCHOOLS
end date: 1995-04-30
principal investigator name: GIMBRONE, MICHAEL A
start date: 1983-05-01
type: Grant
sponsor award id: T35HL007552

Training Grant in Cardiovascular Research
end date: 2030-06-30
principal investigator name: LIBBY, PETER
start date: 1985-07-01
type: Grant
sponsor award id: T32HL007604

Principal Investigator
type: Researcher Role
researcher role of: Seidman, Christine
contributes to: SPECIALIZED CENTER OF RESEARCH IN HEART FAILURE

Co-Principal Investigator
type: Researcher Role
researcher role of: Seidman, Christine
contributes to: SHORT-TERM TRAINING IN HEALTH PROFESSIONAL SCHOOLS

Co-Principal Investigator
type: Researcher Role
researcher role of: Seidman, Christine
contributes to: DIGITAILS--MECHANISM AND REVERSAL STUDIES

Principal Investigator
type: Researcher Role
researcher role of: Seidman, Christine
contributes to: GENETIC ANALYSIS OF FAMILIAL HYPERTROPHIC CARDIOMYOPATHY

Co-Principal Investigator
type: Researcher Role
researcher role of: Seidman, Christine
contributes to: DIGITAILS--MECHANISM AND REVERSAL STUDIES

Co-Principal Investigator
type: Researcher Role
researcher role of: Seidman, Christine
contributes to: SSCOR in Pediatric Heart Development and Disease

Principal Investigator
type: Researcher Role
researcher role of: Seidman, Christine
contributes to: DEVELOPMENT OF STABLE CARDIAC CELL LINES

Co-Principal Investigator
type: Researcher Role
researcher role of: Seidman, Christine
contributes to: MOLECULAR MECHANISMS OF CONGENITAL HEART DISEASE

Principal Investigator
type: Researcher Role
researcher role of: Seidman, Christine
contributes to: GENETICS OF FAMILIAL HYPOCALCIURIC HYPERCALCEMIA

Co-Principal Investigator
type: Researcher Role
researcher role of: Seidman, Christine
contributes to: Using Genetics For Early Phenotyping & Prevention of Hypertrophic Cardiomyopathy

Co-Principal Investigator
type: Researcher Role
researcher role of: Seidman, Christine
contributes to: Regulation of Cardiac Development in Health and Disease

Co-Principal Investigator
type: Researcher Role
researcher role of: Seidman, Christine
contributes to: The Genomic Basis of Congenital Heart Disease and Neurodevelopmental Outcomes

Co-Principal Investigator
type: Researcher Role
researcher role of: Seidman, Christine
contributes to: Using Genetics for Early Phenotyping &Prevention of Hypertrophic Cardiomyopathy

Co-Principal Investigator
type: Researcher Role
researcher role of: Seidman, Christine
contributes to: Training Grant in Cardiovascular Research

Co-Principal Investigator
type: Researcher Role
researcher role of: Seidman, Christine
contributes to: Genomic Effects on Right Ventricular Function, Clinical Features and Outcomes in CHD

Co-Principal Investigator
type: Researcher Role
researcher role of: Seidman, Christine
contributes to: Defining Genetic Architecture and Pathways of DCM

Authorship 342018
type: Authorship
author rank in publication: 3
linked author: Seidman, Christine
linked information resource: Genetic basis of hypertrophic cardiomyopathy: from bench to the clinics.

Authorship 413648
type: Authorship
author rank in publication: 4
linked author: Seidman, Christine
linked information resource: Proximal regulatory domains of rat atrial natriuretic factor gene.

Aggregate penetrance of genomic variants for actionable disorders in European and African Americans.
PubMed Identifier: 27831900
author list: Natarajan P, Gold NB, Bick AG, McLaughlin H, Kraft P, Rehm HL, Peloso GM, Wilson JG, Correa A, Seidman JG, Seidman CE, Kathiresan S, Green RC
published in: Science translational medicine
information resource reference: Aggregate penetrance of genomic variants for actionable disorders in European and African Americans. Sci Transl Med. 2016 11 09; 8(364):364ra151.
journal title abbreviation: Sci Transl Med
publication date: 2016-11-09T00:00:00
year: 2016
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 539539
type: Authorship
author rank in publication: 3
linked author: Seidman, Christine
linked information resource: Inhospital CPR 25 years later: why has survival decreased?

Authorship 930117
type: Authorship
author rank in publication: 18
linked author: Seidman, Christine
linked information resource: Loss of RNA expression and allele-specific expression associated with congenital heart disease.

Authorship 930067
type: Authorship
author rank in publication: 24
linked author: Seidman, Christine
linked information resource: Fulminant Myocarditis with Combination Immune Checkpoint Blockade.

Authorship 934888
type: Authorship
author rank in publication: 11
linked author: Seidman, Christine
linked information resource: Aggregate penetrance of genomic variants for actionable disorders in European and African Americans.

Authorship 935217
type: Authorship
author rank in publication: 31
linked author: Seidman, Christine
linked information resource: Titin-truncating variants affect heart function in disease cohorts and the general population.

Authorship 931950
type: Authorship
author rank in publication: 13
linked author: Seidman, Christine
linked information resource: Single-Cell Resolution of Temporal Gene Expression during Heart Development.

Authorship 932842
type: Authorship
author rank in publication: 12
linked author: Seidman, Christine
linked information resource: Molecular profiling of dilated cardiomyopathy that progresses to heart failure.

Fulminant Myocarditis with Combination Immune Checkpoint Blockade.
PubMed Identifier: 27806233
author list: Johnson DB, Balko JM, Compton ML, Chalkias S, Gorham J, Xu Y, Hicks M, Puzanov I, Alexander MR, Bloomer TL, Becker JR, Slosky DA, Phillips EJ, Pilkinton MA, Craig-Owens L, Kola N, Plautz G, Reshef DS, Deutsch JS, Deering RP, Olenchock BA, Lichtman AH, Roden DM, Seidman CE, Koralnik IJ, Seidman JG, Hoffman RD, Taube JM, Diaz LA, Anders RA, Sosman JA, Moslehi JJ
published in: The New England journal of medicine
information resource reference: Fulminant Myocarditis with Combination Immune Checkpoint Blockade. N Engl J Med. 2016 Nov 03; 375(18):1749-1755.
journal title abbreviation: N Engl J Med
publication date: 2016-11-03T00:00:00
year: 2016
type: Academic Article
type: Article
type: Document
type: Information Resource

Single-Cell Resolution of Temporal Gene Expression during Heart Development.
PubMed Identifier: 27840107
author list: DeLaughter DM, Bick AG, Wakimoto H, McKean D, Gorham JM, Kathiriya IS, Hinson JT, Homsy J, Gray J, Pu W, Bruneau BG, Seidman JG, Seidman CE
published in: Developmental cell
information resource reference: Single-Cell Resolution of Temporal Gene Expression during Heart Development. Dev Cell. 2016 11 21; 39(4):480-490.
journal title abbreviation: Dev Cell
publication date: 2016-11-10T00:00:00
year: 2016
type: Academic Article
type: Article
type: Document
type: Information Resource

Molecular profiling of dilated cardiomyopathy that progresses to heart failure.
PubMed Identifier: 27239561
author list: Burke MA, Chang S, Wakimoto H, Gorham JM, Conner DA, Christodoulou DC, Parfenov MG, DePalma SR, Eminaga S, Konno T, Seidman JG, Seidman CE
published in: JCI insight
information resource reference: Molecular profiling of dilated cardiomyopathy that progresses to heart failure. JCI Insight. 2016 May 05; 1(6).
journal title abbreviation: JCI Insight
publication date: 2016-05-05T00:00:00
year: 2016
type: Academic Article
type: Article
type: Document
type: Information Resource

Titin-truncating variants affect heart function in disease cohorts and the general population.
PubMed Identifier: 27869827
author list: Schafer S, de Marvao A, Adami E, Fiedler LR, Ng B, Khin E, Rackham OJ, van Heesch S, Pua CJ, Kui M, Walsh R, Tayal U, Prasad SK, Dawes TJ, Ko NS, Sim D, Chan LL, Chin CW, Mazzarotto F, Barton PJ, Kreuchwig F, de Kleijn DP, Totman T, Biffi C, Tee N, Rueckert D, Schneider V, Faber A, Regitz-Zagrosek V, Seidman JG, Seidman CE, Linke WA, Kovalik JP, O'Regan D, Ware JS, Hubner N, Cook SA
published in: Nature genetics
information resource reference: Titin-truncating variants affect heart function in disease cohorts and the general population. Nat Genet. 2017 01; 49(1):46-53.
journal title abbreviation: Nat Genet
publication date: 2016-11-21T00:00:00
year: 2016
type: Academic Article
type: Article
type: Document
type: Information Resource

Loss of RNA expression and allele-specific expression associated with congenital heart disease.
PubMed Identifier: 27670201
author list: McKean DM, Homsy J, Wakimoto H, Patel N, Gorham J, DePalma SR, Ware JS, Zaidi S, Ma W, Patel N, Lifton RP, Chung WK, Kim R, Shen Y, Brueckner M, Goldmuntz E, Sharp AJ, Seidman CE, Gelb BD, Seidman JG
published in: Nature communications
information resource reference: Loss of RNA expression and allele-specific expression associated with congenital heart disease. Nat Commun. 2016 09 27; 7:12824.
journal title abbreviation: Nat Commun
publication date: 2016-09-27T00:00:00
year: 2016
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 81414
type: Authorship
author rank in publication: 7
linked author: Seidman, Christine
linked information resource: Isolation of a de novo mutant myocardial beta MHC protein in a pedigree with hypertrophic cardiomyopathy.

Authorship 938351
type: Authorship
author rank in publication: 17
linked author: Seidman, Christine
linked information resource: THSD1 (Thrombospondin Type 1 Domain Containing Protein 1) Mutation in the Pathogenesis of Intracranial Aneurysm and Subarachnoid Hemorrhage.

THSD1 (Thrombospondin Type 1 Domain Containing Protein 1) Mutation in the Pathogenesis of Intracranial Aneurysm and Subarachnoid Hemorrhage.
PubMed Identifier: 27895300
author list: Santiago-Sim T, Fang X, Hennessy ML, Nalbach SV, DePalma SR, Lee MS, Greenway SC, McDonough B, Hergenroeder GW, Patek KJ, Colosimo SM, Qualmann KJ, Hagan JP, Milewicz DM, MacRae CA, Dymecki SM, Seidman CE, Seidman JG, Kim DH
published in: Stroke
information resource reference: THSD1 (Thrombospondin Type 1 Domain Containing Protein 1) Mutation in the Pathogenesis of Intracranial Aneurysm and Subarachnoid Hemorrhage. Stroke. 2016 12; 47(12):3005-3013.
journal title abbreviation: Stroke
publication date: 2016-11-15T00:00:00
year: 2016
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 20690
type: Authorship
author rank in publication: 9
linked author: Seidman, Christine
linked information resource: Spectrum of somatic mitochondrial mutations in five cancers.

Authorship 216990
type: Authorship
author rank in publication: 15
linked author: Seidman, Christine
linked information resource: Heterogeneous myocyte enhancer factor-2 (Mef2) activation in myocytes predicts focal scarring in hypertrophic cardiomyopathy.

Authorship 269957
type: Authorship
author rank in publication: 3
linked author: Seidman, Christine
linked information resource: Phenotypic diversity in hypertrophic cardiomyopathy.

Authorship 27128
type: Authorship
author rank in publication: 1
linked author: Seidman, Christine
linked information resource: The coming of age of cardiovascular science.

Authorship 326418
type: Authorship
author rank in publication: 6
linked author: Seidman, Christine
linked information resource: Homozygous mutation in cardiac troponin T: implications for hypertrophic cardiomyopathy.

Authorship 943448
type: Authorship
author rank in publication: 4
linked author: Seidman, Christine
linked information resource: Clinical and Mechanistic Insights Into the Genetics of Cardiomyopathy.

Authorship 942370
type: Authorship
author rank in publication: 18
linked author: Seidman, Christine
linked information resource: Integrative Analysis of PRKAG2 Cardiomyopathy iPS and Microtissue Models Identifies AMPK as a Regulator of Metabolism, Survival, and Fibrosis.

Clinical and Mechanistic Insights Into the Genetics of Cardiomyopathy.
PubMed Identifier: 28007147
author list: Burke MA, Cook SA, Seidman JG, Seidman CE
published in: Journal of the American College of Cardiology
information resource reference: Clinical and Mechanistic Insights Into the Genetics of Cardiomyopathy. J Am Coll Cardiol. 2016 Dec 27; 68(25):2871-2886.
journal title abbreviation: J Am Coll Cardiol
publication date: 2016-12-27T00:00:00
year: 2016
type: Academic Article
type: Article
type: Document
type: Information Resource

Integrative Analysis of PRKAG2 Cardiomyopathy iPS and Microtissue Models Identifies AMPK as a Regulator of Metabolism, Survival, and Fibrosis.
PubMed Identifier: 28009297
author list: Hinson JT, Chopra A, Lowe A, Sheng CC, Gupta RM, Kuppusamy R, O'Sullivan J, Rowe G, Wakimoto H, Gorham J, Burke MA, Zhang K, Musunuru K, Gerszten RE, Wu SM, Chen CS, Seidman JG, Seidman CE
published in: Cell reports
information resource reference: Integrative Analysis of PRKAG2 Cardiomyopathy iPS and Microtissue Models Identifies AMPK as a Regulator of Metabolism, Survival, and Fibrosis. Cell Rep. 2016 12 20; 17(12):3292-3304.
journal title abbreviation: Cell Rep
publication date: 2016-12-20T00:00:00
year: 2016
type: Academic Article
type: Article
type: Document
type: Information Resource

Preparation of rAAV9 to Overexpress or Knockdown Genes in Mouse Hearts.
PubMed Identifier: 28060283
author list: Ding J, Lin ZQ, Jiang JM, Seidman CE, Seidman JG, Pu WT, Wang DZ
published in: Journal of visualized experiments : JoVE
information resource reference: Preparation of rAAV9 to Overexpress or Knockdown Genes in Mouse Hearts. J Vis Exp. 2016 12 17; (118).
journal title abbreviation: J Vis Exp
publication date: 2016-12-17T00:00:00
year: 2016
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 947492
type: Authorship
author rank in publication: 4
linked author: Seidman, Christine
linked information resource: Preparation of rAAV9 to Overexpress or Knockdown Genes in Mouse Hearts.

Authorship 474244
type: Authorship
author rank in publication: 8
linked author: Seidman, Christine
linked information resource: Optimizing catecholaminergic polymorphic ventricular tachycardia therapy in calsequestrin-mutant mice.

Authorship 504351
type: Authorship
author rank in publication: 14
linked author: Seidman, Christine
linked information resource: A novel custom resequencing array for dilated cardiomyopathy.

Authorship 519879
type: Authorship
author rank in publication: 13
linked author: Seidman, Christine
linked information resource: The spectrum of mutations in TBX3: Genotype/Phenotype relationship in ulnar-mammary syndrome.

Authorship 542676
type: Authorship
author rank in publication: 4
linked author: Seidman, Christine
linked information resource: Tbx5 is required for forelimb bud formation and continued outgrowth.

Authorship 952799
type: Authorship
author rank in publication: 7
linked author: Seidman, Christine
linked information resource: The Long Noncoding RNA Landscape of the Ischemic Human Left Ventricle.

The Long Noncoding RNA Landscape of the Ischemic Human Left Ventricle.
PubMed Identifier: 28115490
author list: Saddic LA, Sigurdsson MI, Chang TW, Mazaika E, Heydarpour M, Shernan SK, Seidman CE, Seidman JG, Aranki SF, Body SC, Muehlschlegel JD
published in: Circulation. Cardiovascular genetics
information resource reference: The Long Noncoding RNA Landscape of the Ischemic Human Left Ventricle. Circ Cardiovasc Genet. 2017 Jan; 10(1).
journal title abbreviation: Circ Cardiovasc Genet
publication date: 2017-01-01T00:00:00
year: 2017
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 560489
type: Authorship
author rank in publication: 15
linked author: Seidman, Christine
linked information resource: Variation in the 4q25 chromosomal locus predicts atrial fibrillation after coronary artery bypass graft surgery.

Authorship 954039
type: Authorship
author rank in publication: 5
linked author: Seidman, Christine
linked information resource: Early remodeling of repolarizing K+ currents in the aMHC403/+ mouse model of familial hypertrophic cardiomyopathy.

Early remodeling of repolarizing K+ currents in the aMHC403/+ mouse model of familial hypertrophic cardiomyopathy.
PubMed Identifier: 28089740
author list: Hueneke R, Adenwala A, Mellor RL, Seidman JG, Seidman CE, Nerbonne JM
published in: Journal of molecular and cellular cardiology
information resource reference: Early remodeling of repolarizing K+ currents in the aMHC403/+ mouse model of familial hypertrophic cardiomyopathy. J Mol Cell Cardiol. 2017 02; 103:93-101.
journal title abbreviation: J Mol Cell Cardiol
publication date: 2017-01-13T00:00:00
year: 2017
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 68613
type: Authorship
author rank in publication: 6
linked author: Seidman, Christine
linked information resource: Mutations in COCH (formerly Coch5b2) cause DFNA9.

Authorship 81423
type: Authorship
author rank in publication: 7
linked author: Seidman, Christine
linked information resource: A single intravenous dose of endotoxin rapidly alters serum lipoproteins and lipid transfer proteins in normal volunteers.

Genetic analysis of susceptibility to experimental autoimmune encephalomyelitis in a cross between SJL/J and B10.S mice.
PubMed Identifier: 8757345
author list: Encinas JA, Lees MB, Sobel RA, Symonowicz C, Greer JM, Shovlin CL, Weiner HL, Seidman CE, Seidman JG, Kuchroo VK
published in: Journal of immunology (Baltimore, Md. : 1950)
information resource reference: Genetic analysis of susceptibility to experimental autoimmune encephalomyelitis in a cross between SJL/J and B10.S mice. J Immunol. 1996 Sep 01; 157(5):2186-92.
journal title abbreviation: J Immunol
publication date: 1996-09-01T00:00:00
year: 1996
type: Academic Article
type: Article
type: Document
type: Information Resource

Mutations in human TBX5 [corrected] cause limb and cardiac malformation in Holt-Oram syndrome.
PubMed Identifier: 8988165
author list: Basson CT, Bachinsky DR, Lin RC, Levi T, Elkins JA, Soults J, Grayzel D, Kroumpouzou E, Traill TA, Leblanc-Straceski J, Renault B, Kucherlapati R, Seidman JG, Seidman CE
published in: Nature genetics
information resource reference: Mutations in human TBX5 [corrected] cause limb and cardiac malformation in Holt-Oram syndrome. Nat Genet. 1997 Jan; 15(1):30-5.
journal title abbreviation: Nat Genet
publication date: 1997-01-01T00:00:00
year: 1997
type: Academic Article
type: Article
type: Document
type: Information Resource

Hereditary inclusion body myopathy maps to chromosome 9p1-q1.
PubMed Identifier: 8789455
author list: Mitrani-Rosenbaum S, Argov Z, Blumenfeld A, Seidman CE, Seidman JG
published in: Human molecular genetics
information resource reference: Hereditary inclusion body myopathy maps to chromosome 9p1-q1. Hum Mol Genet. 1996 Jan; 5(1):159-163.
journal title abbreviation: Hum Mol Genet
publication date: 1996-01-01T00:00:00
year: 1996
type: Academic Article
type: Article
type: Document
type: Information Resource

A gene for non-syndromic autosomal dominant progressive postlingual sensorineural hearing loss maps to chromosome 14q12-13.
PubMed Identifier: 8817345
author list: Manolis EN, Yandavi N, Nadol JB, Eavey RD, McKenna M, Rosenbaum S, Khetarpal U, Halpin C, Merchant SN, Duyk GM, MacRae C, Seidman CE, Seidman JG
published in: Human molecular genetics
information resource reference: A gene for non-syndromic autosomal dominant progressive postlingual sensorineural hearing loss maps to chromosome 14q12-13. Hum Mol Genet. 1996 Jul; 5(7):1047-50.
journal title abbreviation: Hum Mol Genet
publication date: 1996-07-01T00:00:00
year: 1996
type: Academic Article
type: Article
type: Document
type: Information Resource

Electrophysiological abnormalities and arrhythmias in alpha MHC mutant familial hypertrophic cardiomyopathy mice.
PubMed Identifier: 9045856
author list: Berul CI, Christe ME, Aronovitz MJ, Seidman CE, Seidman JG, Mendelsohn ME
published in: The Journal of clinical investigation
information resource reference: Electrophysiological abnormalities and arrhythmias in alpha MHC mutant familial hypertrophic cardiomyopathy mice. J Clin Invest. 1997 Feb 15; 99(4):570-6.
journal title abbreviation: J Clin Invest
publication date: 1997-02-15T00:00:00
year: 1997
type: Academic Article
type: Article
type: Document
type: Information Resource

Amyloid-beta proteins activate Ca(2+)-permeable channels through calcium-sensing receptors.
PubMed Identifier: 9067864
author list: Ye C, Ho-Pao CL, Kanazirska M, Quinn S, Rogers K, Seidman CE, Seidman JG, Brown EM, Vassilev PM
published in: Journal of neuroscience research
information resource reference: Amyloid-beta proteins activate Ca(2+)-permeable channels through calcium-sensing receptors. J Neurosci Res. 1997 Mar 01; 47(5):547-54.
journal title abbreviation: J Neurosci Res
publication date: 1997-03-01T00:00:00
year: 1997
type: Academic Article
type: Article
type: Document
type: Information Resource

The spectrum of mutations in TBX3: Genotype/Phenotype relationship in ulnar-mammary syndrome.
PubMed Identifier: 10330342
author list: Bamshad M, Le T, Watkins WS, Dixon ME, Kramer BE, Roeder AD, Carey JC, Root S, Schinzel A, Van Maldergem L, Gardner RJ, Lin RC, Seidman CE, Seidman JG, Wallerstein R, Moran E, Sutphen R, Campbell CE, Jorde LB
published in: American journal of human genetics
information resource reference: The spectrum of mutations in TBX3: Genotype/Phenotype relationship in ulnar-mammary syndrome. Am J Hum Genet. 1999 Jun; 64(6):1550-62.
journal title abbreviation: Am J Hum Genet
publication date: 1999-06-01T00:00:00
year: 1999
type: Academic Article
type: Article
type: Document
type: Information Resource

Altered regulatory function of two familial hypertrophic cardiomyopathy troponin T mutants.
PubMed Identifier: 10529204
author list: Mukherjea P, Tong L, Seidman JG, Seidman CE, Hitchcock-DeGregori SE
published in: Biochemistry
information resource reference: Altered regulatory function of two familial hypertrophic cardiomyopathy troponin T mutants. Biochemistry. 1999 Oct 05; 38(40):13296-301.
journal title abbreviation: Biochemistry
publication date: 1999-10-05T00:00:00
year: 1999
type: Academic Article
type: Article
type: Document
type: Information Resource

A novel missense mutation in the paired domain of PAX9 causes non-syndromic oligodontia.
PubMed Identifier: 14689302
author list: Jumlongras D, Lin JY, Chapra A, Seidman CE, Seidman JG, Maas RL, Olsen BR
published in: Human genetics
information resource reference: A novel missense mutation in the paired domain of PAX9 causes non-syndromic oligodontia. Hum Genet. 2004 Feb; 114(3):242-9.
journal title abbreviation: Hum Genet
publication date: 2003-12-19T00:00:00
year: 2003
type: Academic Article
type: Article
type: Document
type: Information Resource

Three inherited disorders of calcium sensing.
PubMed Identifier: 8965680
author list: Pollak MR, Seidman CE, Brown EM
published in: Medicine
information resource reference: Three inherited disorders of calcium sensing. Medicine (Baltimore). 1996 May; 75(3):115-23.
journal title abbreviation: Medicine (Baltimore)
publication date: 1996-05-01T00:00:00
year: 1996
type: Academic Article
type: Article
type: Document
type: Information Resource

The management of hypertrophic cardiomyopathy.
PubMed Identifier: 9052657
author list: Spirito P, Seidman CE, McKenna WJ, Maron BJ
published in: The New England journal of medicine
information resource reference: The management of hypertrophic cardiomyopathy. N Engl J Med. 1997 Mar 13; 336(11):775-85.
journal title abbreviation: N Engl J Med
publication date: 1997-03-13T00:00:00
year: 1997
type: Academic Article
type: Article
type: Document
type: Information Resource

A new autosomal dominant disorder of pyogenic sterile arthritis, pyoderma gangrenosum, and acne: PAPA syndrome.
PubMed Identifier: 9212761
author list: Lindor NM, Arsenault TM, Solomon H, Seidman CE, McEvoy MT
published in: Mayo Clinic proceedings
information resource reference: A new autosomal dominant disorder of pyogenic sterile arthritis, pyoderma gangrenosum, and acne: PAPA syndrome. Mayo Clin Proc. 1997 Jul; 72(7):611-5.
journal title abbreviation: Mayo Clin Proc
publication date: 1997-07-01T00:00:00
year: 1997
type: Academic Article
type: Article
type: Document
type: Information Resource

Deficient cation channel regulation in neurons from mice with targeted disruption of the extracellular Ca2+-sensing receptor gene.
PubMed Identifier: 9288833
author list: Ye C, Ho-Pao CL, Kanazirska M, Quinn S, Seidman CE, Seidman JG, Brown EM, Vassilev PM
published in: Brain research bulletin
information resource reference: Deficient cation channel regulation in neurons from mice with targeted disruption of the extracellular Ca2+-sensing receptor gene. Brain Res Bull. 1997; 44(1):75-84.
journal title abbreviation: Brain Res Bull
publication date: 1997-01-01T00:00:00
year: 1997
type: Academic Article
type: Article
type: Document
type: Information Resource

Targeted ablation of the murine alpha-tropomyosin gene.
PubMed Identifier: 9400381
author list: Blanchard EM, Iizuka K, Christe M, Conner DA, Geisterfer-Lowrance A, Schoen FJ, Maughan DW, Seidman CE, Seidman JG
published in: Circulation research
information resource reference: Targeted ablation of the murine alpha-tropomyosin gene. Circ Res. 1997 Dec; 81(6):1005-10.
journal title abbreviation: Circ Res
publication date: 1997-12-01T00:00:00
year: 1997
type: Academic Article
type: Article
type: Document
type: Information Resource

Cardiac myosin missense mutations cause dilated cardiomyopathy in mouse models and depress molecular motor function.
PubMed Identifier: 16983074
author list: Schmitt JP, Debold EP, Ahmad F, Armstrong A, Frederico A, Conner DA, Mende U, Lohse MJ, Warshaw D, Seidman CE, Seidman JG
published in: Proceedings of the National Academy of Sciences of the United States of America
information resource reference: Cardiac myosin missense mutations cause dilated cardiomyopathy in mouse models and depress molecular motor function. Proc Natl Acad Sci U S A. 2006 Sep 26; 103(39):14525-30.
journal title abbreviation: Proc Natl Acad Sci U S A
publication date: 2006-09-18T00:00:00
year: 2006
type: Academic Article
type: Article
type: Document
type: Information Resource

Genetics of cardiovascular disease.
PubMed Identifier: 11080139
author list: Milewicz DM, Seidman CE
published in: Circulation
information resource reference: Genetics of cardiovascular disease. Circulation. 2000 Nov 14; 102(20 Suppl 4):IV103-11.
journal title abbreviation: Circulation
publication date: 2000-11-14T00:00:00
year: 2000
type: Academic Article
type: Article
type: Document
type: Information Resource

Accelerated cardiomyopathy in mice with overexpression of cardiac G(s)alpha and a missense mutation in the alpha-myosin heavy chain.
PubMed Identifier: 11827928
author list: Hardt SE, Geng YJ, Montagne O, Asai K, Hong C, Yang GP, Bishop SP, Kim SJ, Vatner DE, Seidman CE, Seidman JG, Homcy CJ, Vatner SF
published in: Circulation
information resource reference: Accelerated cardiomyopathy in mice with overexpression of cardiac G(s)alpha and a missense mutation in the alpha-myosin heavy chain. Circulation. 2002 Feb 05; 105(5):614-20.
journal title abbreviation: Circulation
publication date: 2002-02-05T00:00:00
year: 2002
type: Academic Article
type: Article
type: Document
type: Information Resource

Effects of shrimp consumption on plasma lipoproteins.
PubMed Identifier: 8901790
author list: De Oliveira e Silva ER, Seidman CE, Tian JJ, Hudgins LC, Sacks FM, Breslow JL
published in: The American journal of clinical nutrition
information resource reference: Effects of shrimp consumption on plasma lipoproteins. Am J Clin Nutr. 1996 Nov; 64(5):712-7.
journal title abbreviation: Am J Clin Nutr
publication date: 1996-11-01T00:00:00
year: 1996
type: Academic Article
type: Article
type: Document
type: Information Resource

https://connects.catalyst.harvard.edu/Profiles/profile/760483
PubMed Identifier: 9831629
author list: Sehayek E, Nath C, Heinemann T, McGee M, Seidman CE, Samuel P, Breslow JL
published in: Journal of lipid research
information resource reference: U-shape relationship between change in dietary cholesterol absorption and plasma lipoprotein responsiveness and evidence for extreme interindividual variation in dietary cholesterol absorption in humans. J Lipid Res. 1998 Dec; 39(12):2415-22.
journal title abbreviation: J Lipid Res
publication date: 1998-12-01T00:00:00
year: 1998
type: Academic Article
type: Article
type: Document
type: Information Resource
label: U-shape relationship between change in dietary cholesterol absorption and plasma lipoprotein responsiveness and evidence for extreme interindividual variation in dietary cholesterol absorption in humans.

Alcohol consumption raises HDL cholesterol levels by increasing the transport rate of apolipoproteins A-I and A-II.
PubMed Identifier: 11067787
author list: De Oliveira E Silva ER, Foster D, McGee Harper M, Seidman CE, Smith JD, Breslow JL, Brinton EA
published in: Circulation
information resource reference: Alcohol consumption raises HDL cholesterol levels by increasing the transport rate of apolipoproteins A-I and A-II. Circulation. 2000 Nov 07; 102(19):2347-52.
journal title abbreviation: Circulation
publication date: 2000-11-07T00:00:00
year: 2000
type: Academic Article
type: Article
type: Document
type: Information Resource

Mutations in sarcomere protein genes as a cause of dilated cardiomyopathy.
PubMed Identifier: 11106718
author list: Kamisago M, Sharma SD, DePalma SR, Solomon S, Sharma P, McDonough B, Smoot L, Mullen MP, Woolf PK, Wigle ED, Seidman JG, Seidman CE
published in: The New England journal of medicine
information resource reference: Mutations in sarcomere protein genes as a cause of dilated cardiomyopathy. N Engl J Med. 2000 Dec 07; 343(23):1688-96.
journal title abbreviation: N Engl J Med
publication date: 2000-12-07T00:00:00
year: 2000
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 968151
type: Authorship
author rank in publication: 18
linked author: Seidman, Christine
linked information resource: The Burden of Early Phenotypes and the Influence of Wall Thickness in Hypertrophic Cardiomyopathy Mutation Carriers: Findings From the HCMNet Study.

The Burden of Early Phenotypes and the Influence of Wall Thickness in Hypertrophic Cardiomyopathy Mutation Carriers: Findings From the HCMNet Study.
PubMed Identifier: 28241245
author list: Ho CY, Day SM, Colan SD, Russell MW, Towbin JA, Sherrid MV, Canter CE, Jefferies JL, Murphy AM, Cirino AL, Abraham TP, Taylor M, Mestroni L, Bluemke DA, Jarolim P, Shi L, Sleeper LA, Seidman CE, Orav EJ
published in: JAMA cardiology
information resource reference: The Burden of Early Phenotypes and the Influence of Wall Thickness in Hypertrophic Cardiomyopathy Mutation Carriers: Findings From the HCMNet Study. JAMA Cardiol. 2017 04 01; 2(4):419-428.
journal title abbreviation: JAMA Cardiol
publication date: 2017-04-01T00:00:00
year: 2017
type: Academic Article
type: Article
type: Document
type: Information Resource

Altered cardiac excitation-contraction coupling in mutant mice with familial hypertrophic cardiomyopathy.
PubMed Identifier: 10074482
author list: Gao WD, Pérez NG, Seidman CE, Seidman JG, Marbán E
published in: The Journal of clinical investigation
information resource reference: Altered cardiac excitation-contraction coupling in mutant mice with familial hypertrophic cardiomyopathy. J Clin Invest. 1999 Mar; 103(5):661-6.
journal title abbreviation: J Clin Invest
publication date: 1999-03-01T00:00:00
year: 1999
type: Academic Article
type: Article
type: Document
type: Information Resource

Characterization of endoglin and identification of novel mutations in hereditary hemorrhagic telangiectasia.
PubMed Identifier: 9245986
author list: Shovlin CL, Hughes JM, Scott J, Seidman CE, Seidman JG
published in: American journal of human genetics
information resource reference: Characterization of endoglin and identification of novel mutations in hereditary hemorrhagic telangiectasia. Am J Hum Genet. 1997 Jul; 61(1):68-79.
journal title abbreviation: Am J Hum Genet
publication date: 1997-07-01T00:00:00
year: 1997
type: Academic Article
type: Article
type: Document
type: Information Resource

Chamber-specific cardiac expression of Tbx5 and heart defects in Holt-Oram syndrome.
PubMed Identifier: 10373308
author list: Bruneau BG, Logan M, Davis N, Levi T, Tabin CJ, Seidman JG, Seidman CE
published in: Developmental biology
information resource reference: Chamber-specific cardiac expression of Tbx5 and heart defects in Holt-Oram syndrome. Dev Biol. 1999 Jul 01; 211(1):100-8.
journal title abbreviation: Dev Biol
publication date: 1999-07-01T00:00:00
year: 1999
type: Academic Article
type: Article
type: Document
type: Information Resource

Hereditary postlingual sensorineural hearing loss mapping to chromosome Xq21.
PubMed Identifier: 10503584
author list: Manolis EN, Eavey RD, Sangwatanaroj S, Halpin C, Rosenbaum S, Watkins H, Jarcho J, Seidman CE, Seidman JG
published in: The American journal of otology
information resource reference: Hereditary postlingual sensorineural hearing loss mapping to chromosome Xq21. Am J Otol. 1999 Sep; 20(5):621-6.
journal title abbreviation: Am J Otol
publication date: 1999-09-01T00:00:00
year: 1999
type: Academic Article
type: Article
type: Document
type: Information Resource

Dilated cardiomyopathy in homozygous myosin-binding protein-C mutant mice
PubMed Identifier: 10606631
author list: McConnell BK, Jones KA, Fatkin D, Arroyo LH, Lee RT, Aristizabal O, Turnbull DH, Georgakopoulos D, Kass D, Bond M, Niimura H, Schoen FJ, Conner D, Fischman DA, Seidman CE, Seidman JG
published in: The Journal of clinical investigation
information resource reference: Dilated cardiomyopathy in homozygous myosin-binding protein-C mutant mice J Clin Invest. 1999 Dec; 104(12):1771.
journal title abbreviation: J Clin Invest
publication date: 1999-12-01T00:00:00
year: 1999
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 971320
type: Authorship
author rank in publication: 30
linked author: Seidman, Christine
linked information resource: Exome-wide association study reveals novel susceptibility genes to sporadic dilated cardiomyopathy.

Exome-wide association study reveals novel susceptibility genes to sporadic dilated cardiomyopathy.
PubMed Identifier: 28296976
author list: Esslinger U, Garnier S, Korniat A, Proust C, Kararigas G, Müller-Nurasyid M, Empana JP, Morley MP, Perret C, Stark K, Bick AG, Prasad SK, Kriebel J, Li J, Tiret L, Strauch K, O'Regan DP, Marguiles KB, Seidman JG, Boutouyrie P, Lacolley P, Jouven X, Hengstenberg C, Komajda M, Hakonarson H, Isnard R, Arbustini E, Grallert H, Cook SA, Seidman CE, Regitz-Zagrosek V, Cappola TP, Charron P, Cambien F, Villard E
published in: PloS one
information resource reference: Exome-wide association study reveals novel susceptibility genes to sporadic dilated cardiomyopathy. PLoS One. 2017; 12(3):e0172995.
journal title abbreviation: PLoS One
publication date: 2017-03-15T00:00:00
year: 2017
type: Academic Article
type: Article
type: Document
type: Information Resource

Homozygous mutation in cardiac troponin T: implications for hypertrophic cardiomyopathy.
PubMed Identifier: 11034944
author list: Ho CY, Lever HM, DeSanctis R, Farver CF, Seidman JG, Seidman CE
published in: Circulation
information resource reference: Homozygous mutation in cardiac troponin T: implications for hypertrophic cardiomyopathy. Circulation. 2000 Oct 17; 102(16):1950-5.
journal title abbreviation: Circulation
publication date: 2000-10-17T00:00:00
year: 2000
type: Academic Article
type: Article
type: Document
type: Information Resource

Development of left ventricular hypertrophy in adults in hypertrophic cardiomyopathy caused by cardiac myosin-binding protein C gene mutations.
PubMed Identifier: 11499718
author list: Maron BJ, Niimura H, Casey SA, Soper MK, Wright GB, Seidman JG, Seidman CE
published in: Journal of the American College of Cardiology
information resource reference: Development of left ventricular hypertrophy in adults in hypertrophic cardiomyopathy caused by cardiac myosin-binding protein C gene mutations. J Am Coll Cardiol. 2001 Aug; 38(2):315-21.
journal title abbreviation: J Am Coll Cardiol
publication date: 2001-08-01T00:00:00
year: 2001
type: Academic Article
type: Article
type: Document
type: Information Resource

The role of cardiac troponin T quantity and function in cardiac development and dilated cardiomyopathy.
PubMed Identifier: 18612386
author list: Ahmad F, Banerjee SK, Lage ML, Huang XN, Smith SH, Saba S, Rager J, Conner DA, Janczewski AM, Tobita K, Tinney JP, Moskowitz IP, Perez-Atayde AR, Keller BB, Mathier MA, Shroff SG, Seidman CE, Seidman JG
published in: PloS one
information resource reference: The role of cardiac troponin T quantity and function in cardiac development and dilated cardiomyopathy. PLoS One. 2008 Jul 09; 3(7):e2642.
journal title abbreviation: PLoS One
publication date: 2008-07-09T00:00:00
year: 2008
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 972113
type: Authorship
author rank in publication: 27
linked author: Seidman, Christine
linked information resource: Bedside Back to Bench: Building Bridges between Basic and Clinical Genomic Research.

Bedside Back to Bench: Building Bridges between Basic and Clinical Genomic Research.
PubMed Identifier: 28340351
author list: Manolio TA, Fowler DM, Starita LM, Haendel MA, MacArthur DG, Biesecker LG, Worthey E, Chisholm RL, Green ED, Jacob HJ, McLeod HL, Roden D, Rodriguez LL, Williams MS, Cooper GM, Cox NJ, Herman GE, Kingsmore S, Lo C, Lutz C, MacRae CA, Nussbaum RL, Ordovas JM, Ramos EM, Robinson PN, Rubinstein WS, Seidman C, Stranger BE, Wang H, Westerfield M, Bult C
published in: Cell
information resource reference: Bedside Back to Bench: Building Bridges between Basic and Clinical Genomic Research. Cell. 2017 03 23; 169(1):6-12.
journal title abbreviation: Cell
publication date: 2017-03-23T00:00:00
year: 2017
type: Academic Article
type: Article
type: Document
type: Information Resource

A single intravenous dose of endotoxin rapidly alters serum lipoproteins and lipid transfer proteins in normal volunteers.
PubMed Identifier: 12754273
author list: Hudgins LC, Parker TS, Levine DM, Gordon BR, Saal SD, Jiang XC, Seidman CE, Tremaroli JD, Lai J, Rubin AL
published in: Journal of lipid research
information resource reference: A single intravenous dose of endotoxin rapidly alters serum lipoproteins and lipid transfer proteins in normal volunteers. J Lipid Res. 2003 Aug; 44(8):1489-98.
journal title abbreviation: J Lipid Res
publication date: 2003-05-16T00:00:00
year: 2003
type: Academic Article
type: Article
type: Document
type: Information Resource

A mouse model of congenital heart disease: cardiac arrhythmias and atrial septal defect caused by haploinsufficiency of the cardiac transcription factor Csx/Nkx2.5.
PubMed Identifier: 12858555
author list: Tanaka M, Berul CI, Ishii M, Jay PY, Wakimoto H, Douglas P, Yamasaki N, Kawamoto T, Gehrmann J, Maguire CT, Schinke M, Seidman CE, Seidman JG, Kurachi Y, Izumo S
published in: Cold Spring Harbor symposia on quantitative biology
information resource reference: A mouse model of congenital heart disease: cardiac arrhythmias and atrial septal defect caused by haploinsufficiency of the cardiac transcription factor Csx/Nkx2.5. Cold Spring Harb Symp Quant Biol. 2002; 67:317-25.
journal title abbreviation: Cold Spring Harb Symp Quant Biol
publication date: 2002-01-01T00:00:00
year: 2002
type: Academic Article
type: Article
type: Document
type: Information Resource

Electrophysiologic characterization and postnatal development of ventricular pre-excitation in a mouse model of cardiac hypertrophy and Wolff-Parkinson-White syndrome.
PubMed Identifier: 12957447
author list: Patel VV, Arad M, Moskowitz IP, Maguire CT, Branco D, Seidman JG, Seidman CE, Berul CI
published in: Journal of the American College of Cardiology
information resource reference: Electrophysiologic characterization and postnatal development of ventricular pre-excitation in a mouse model of cardiac hypertrophy and Wolff-Parkinson-White syndrome. J Am Coll Cardiol. 2003 Sep 03; 42(5):942-51.
journal title abbreviation: J Am Coll Cardiol
publication date: 2003-09-03T00:00:00
year: 2003
type: Academic Article
type: Article
type: Document
type: Information Resource

Mutations in cardiac myosin heavy chain genes cause familial hypertrophic cardiomyopathy.
PubMed Identifier: 1806760
author list: Seidman CE, Seidman JG
published in: Molecular biology & medicine
information resource reference: Mutations in cardiac myosin heavy chain genes cause familial hypertrophic cardiomyopathy. Mol Biol Med. 1991 Apr; 8(2):159-66.
journal title abbreviation: Mol Biol Med
publication date: 1991-04-01T00:00:00
year: 1991
type: Academic Article
type: Article
type: Document
type: Information Resource

Genetic heterogeneity evidenced by low incidence of KAL-1 gene mutations in sporadic cases of gonadotropin-releasing hormone deficiency.
PubMed Identifier: 8989261
author list: Georgopoulos NA, Pralong FP, Seidman CE, Seidman JG, Crowley WF, Vallejo M
published in: The Journal of clinical endocrinology and metabolism
information resource reference: Genetic heterogeneity evidenced by low incidence of KAL-1 gene mutations in sporadic cases of gonadotropin-releasing hormone deficiency. J Clin Endocrinol Metab. 1997 Jan; 82(1):213-7.
journal title abbreviation: J Clin Endocrinol Metab
publication date: 1997-01-01T00:00:00
year: 1997
type: Academic Article
type: Article
type: Document
type: Information Resource

Mutations in a novel cochlear gene cause DFNA9, a human nonsyndromic deafness with vestibular dysfunction.
PubMed Identifier: 9806553
author list: Robertson NG, Lu L, Heller S, Merchant SN, Eavey RD, McKenna M, Nadol JB, Miyamoto RT, Linthicum FH, Lubianca Neto JF, Hudspeth AJ, Seidman CE, Morton CC, Seidman JG
published in: Nature genetics
information resource reference: Mutations in a novel cochlear gene cause DFNA9, a human nonsyndromic deafness with vestibular dysfunction. Nat Genet. 1998 Nov; 20(3):299-303.
journal title abbreviation: Nat Genet
publication date: 1998-11-01T00:00:00
year: 1998
type: Academic Article
type: Article
type: Document
type: Information Resource

Mutations in ALPK3 underlie neonatal onset of cardiac hypertrophy
end date: 2016-09-01T00:00:00
start date: 2016-06-01T00:00:00
type: Mentoring - Completed Student Project
overview: Summer

Ventricular arrhythmia vulnerability in cardiomyopathic mice with homozygous mutant Myosin-binding protein C gene.
PubMed Identifier: 11723028
author list: Berul CI, McConnell BK, Wakimoto H, Moskowitz IP, Maguire CT, Semsarian C, Vargas MM, Gehrmann J, Seidman CE, Seidman JG
published in: Circulation
information resource reference: Ventricular arrhythmia vulnerability in cardiomyopathic mice with homozygous mutant Myosin-binding protein C gene. Circulation. 2001 Nov 27; 104(22):2734-9.
journal title abbreviation: Circulation
publication date: 2001-11-27T00:00:00
year: 2001
type: Academic Article
type: Article
type: Document
type: Information Resource

Mutations in CD2BP1 disrupt binding to PTP PEST and are responsible for PAPA syndrome, an autoinflammatory disorder.
PubMed Identifier: 11971877
author list: Wise CA, Gillum JD, Seidman CE, Lindor NM, Veile R, Bashiardes S, Lovett M
published in: Human molecular genetics
information resource reference: Mutations in CD2BP1 disrupt binding to PTP PEST and are responsible for PAPA syndrome, an autoinflammatory disorder. Hum Mol Genet. 2002 Apr 15; 11(8):961-9.
journal title abbreviation: Hum Mol Genet
publication date: 2002-04-15T00:00:00
year: 2002
type: Academic Article
type: Article
type: Document
type: Information Resource

Identification, characterization, and chromosomal localization of the human homolog (hES) of ES/130.
PubMed Identifier: 8812507
author list: Basson CT, MacRae CA, Schoenberg-Fejzo M, Morton CC, Spinner NB, Genin A, Krug E, Seidman JG, Seidman CE
published in: Genomics
information resource reference: Identification, characterization, and chromosomal localization of the human homolog (hES) of ES/130. Genomics. 1996 Aug 01; 35(3):628-31.
journal title abbreviation: Genomics
publication date: 1996-08-01T00:00:00
year: 1996
type: Academic Article
type: Article
type: Document
type: Information Resource

Expression and functional assessment of a truncated cardiac troponin T that causes hypertrophic cardiomyopathy. Evidence for a dominant negative action.
PubMed Identifier: 8958207
author list: Watkins H, Seidman CE, Seidman JG, Feng HS, Sweeney HL
published in: The Journal of clinical investigation
information resource reference: Expression and functional assessment of a truncated cardiac troponin T that causes hypertrophic cardiomyopathy. Evidence for a dominant negative action. J Clin Invest. 1996 Dec 01; 98(11):2456-61.
journal title abbreviation: J Clin Invest
publication date: 1996-12-01T00:00:00
year: 1996
type: Academic Article
type: Article
type: Document
type: Information Resource

Clinical features of hypertrophic cardiomyopathy caused by mutation of a "hot spot" in the alpha-tropomyosin gene.
PubMed Identifier: 9060904
author list: Coviello DA, Maron BJ, Spirito P, Watkins H, Vosberg HP, Thierfelder L, Schoen FJ, Seidman JG, Seidman CE
published in: Journal of the American College of Cardiology
information resource reference: Clinical features of hypertrophic cardiomyopathy caused by mutation of a "hot spot" in the alpha-tropomyosin gene. J Am Coll Cardiol. 1997 Mar 01; 29(3):635-40.
journal title abbreviation: J Am Coll Cardiol
publication date: 1997-03-01T00:00:00
year: 1997
type: Academic Article
type: Article
type: Document
type: Information Resource

Effects of two familial hypertrophic cardiomyopathy-causing mutations on alpha-tropomyosin structure and function.
PubMed Identifier: 9109674
author list: Golitsina N, An Y, Greenfield NJ, Thierfelder L, Iizuka K, Seidman JG, Seidman CE, Lehrer SS, Hitchcock-DeGregori SE
published in: Biochemistry
information resource reference: Effects of two familial hypertrophic cardiomyopathy-causing mutations on alpha-tropomyosin structure and function. Biochemistry. 1997 Apr 15; 36(15):4637-42.
journal title abbreviation: Biochemistry
publication date: 1997-04-15T00:00:00
year: 1997
type: Academic Article
type: Article
type: Document
type: Information Resource

Molecular genetic studies of familial hypertrophic cardiomyopathy.
PubMed Identifier: 9879437
author list: Seidman CE, Seidman JG
published in: Basic research in cardiology
information resource reference: Molecular genetic studies of familial hypertrophic cardiomyopathy. Basic Res Cardiol. 1998; 93 Suppl 3:13-6.
journal title abbreviation: Basic Res Cardiol
publication date: 1998-01-01T00:00:00
year: 1998
type: Academic Article
type: Article
type: Document
type: Information Resource

Contemporary evaluation and management of hypertrophic cardiomyopathy.
PubMed Identifier: 12221045
author list: Braunwald E, Seidman CE, Sigwart U
published in: Circulation
information resource reference: Contemporary evaluation and management of hypertrophic cardiomyopathy. Circulation. 2002 Sep 10; 106(11):1312-6.
journal title abbreviation: Circulation
publication date: 2002-09-10T00:00:00
year: 2002
type: Academic Article
type: Article
type: Document
type: Information Resource

cis-dominance of rat atrial natriuretic factor gene regulatory sequences in transgenic mice.
PubMed Identifier: 1723347
author list: Seidman CE, Schmidt EV, Seidman JG
published in: Canadian journal of physiology and pharmacology
information resource reference: cis-dominance of rat atrial natriuretic factor gene regulatory sequences in transgenic mice. Can J Physiol Pharmacol. 1991 Oct; 69(10):1486-92.
journal title abbreviation: Can J Physiol Pharmacol
publication date: 1991-10-01T00:00:00
year: 1991
type: Academic Article
type: Article
type: Document
type: Information Resource

Pyogenic arthritis, pyoderma gangrenosum, and acne syndrome maps to chromosome 15q.
PubMed Identifier: 10729114
author list: Yeon HB, Lindor NM, Seidman JG, Seidman CE
published in: American journal of human genetics
information resource reference: Pyogenic arthritis, pyoderma gangrenosum, and acne syndrome maps to chromosome 15q. Am J Hum Genet. 2000 Apr; 66(4):1443-8.
journal title abbreviation: Am J Hum Genet
publication date: 2000-03-21T00:00:00
year: 2000
type: Academic Article
type: Article
type: Document
type: Information Resource

Atrial natriuretic factor and related peptide hormones.
PubMed Identifier: 1652921
author list: Rosenzweig A, Seidman CE
published in: Annual review of biochemistry
information resource reference: Atrial natriuretic factor and related peptide hormones. Annu Rev Biochem. 1991; 60:229-55.
journal title abbreviation: Annu Rev Biochem
publication date: 1991-01-01T00:00:00
year: 1991
type: Academic Article
type: Article
type: Document
type: Information Resource

The gene responsible for familial hypocalciuric hypercalcemia maps to chromosome 3q in four unrelated families.
PubMed Identifier: 1302026
author list: Chou YH, Brown EM, Levi T, Crowe G, Atkinson AB, Arnqvist HJ, Toss G, Fuleihan GE, Seidman JG, Seidman CE
published in: Nature genetics
information resource reference: The gene responsible for familial hypocalciuric hypercalcemia maps to chromosome 3q in four unrelated families. Nat Genet. 1992 Jul; 1(4):295-300.
journal title abbreviation: Nat Genet
publication date: 1992-07-01T00:00:00
year: 1992
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 978835
type: Authorship
author rank in publication: 21
linked author: Seidman, Christine
linked information resource: Macrophages Facilitate Electrical Conduction in the Heart.

Macrophages Facilitate Electrical Conduction in the Heart.
PubMed Identifier: 28431249
author list: Hulsmans M, Clauss S, Xiao L, Aguirre AD, King KR, Hanley A, Hucker WJ, Wülfers EM, Seemann G, Courties G, Iwamoto Y, Sun Y, Savol AJ, Sager HB, Lavine KJ, Fishbein GA, Capen DE, Da Silva N, Miquerol L, Wakimoto H, Seidman CE, Seidman JG, Sadreyev RI, Naxerova K, Mitchell RN, Brown D, Libby P, Weissleder R, Swirski FK, Kohl P, Vinegoni C, Milan DJ, Ellinor PT, Nahrendorf M
published in: Cell
information resource reference: Macrophages Facilitate Electrical Conduction in the Heart. Cell. 2017 04 20; 169(3):510-522.e20.
journal title abbreviation: Cell
publication date: 2017-04-20T00:00:00
year: 2017
type: Academic Article
type: Article
type: Document
type: Information Resource

The metabolic and immunologic effects of short-term thalidomide treatment of patients infected with the human immunodeficiency virus.
PubMed Identifier: 9264292
author list: Haslett P, Hempstead M, Seidman C, Diakun J, Vasquez D, Freedman VH, Kaplan G
published in: AIDS research and human retroviruses
information resource reference: The metabolic and immunologic effects of short-term thalidomide treatment of patients infected with the human immunodeficiency virus. AIDS Res Hum Retroviruses. 1997 Aug 10; 13(12):1047-54.
journal title abbreviation: AIDS Res Hum Retroviruses
publication date: 1997-08-10T00:00:00
year: 1997
type: Academic Article
type: Article
type: Document
type: Information Resource

Rescue of cardiomyocyte dysfunction by phospholamban ablation does not prevent ventricular failure in genetic hypertrophy.
PubMed Identifier: 12639992
author list: Song Q, Schmidt AG, Hahn HS, Carr AN, Frank B, Pater L, Gerst M, Young K, Hoit BD, McConnell BK, Haghighi K, Seidman CE, Seidman JG, Dorn GW, Kranias EG
published in: The Journal of clinical investigation
information resource reference: Rescue of cardiomyocyte dysfunction by phospholamban ablation does not prevent ventricular failure in genetic hypertrophy. J Clin Invest. 2003 Mar; 111(6):859-67.
journal title abbreviation: J Clin Invest
publication date: 2003-03-01T00:00:00
year: 2003
type: Academic Article
type: Article
type: Document
type: Information Resource

Tbx5 is required for forelimb bud formation and continued outgrowth.
PubMed Identifier: 12736217
author list: Rallis C, Bruneau BG, Del Buono J, Seidman CE, Seidman JG, Nissim S, Tabin CJ, Logan MP
published in: Development (Cambridge, England)
information resource reference: Tbx5 is required for forelimb bud formation and continued outgrowth. Development. 2003 Jun; 130(12):2741-51.
journal title abbreviation: Development
publication date: 2003-06-01T00:00:00
year: 2003
type: Academic Article
type: Article
type: Document
type: Information Resource

Adult Hallervorden-Spatz syndrome simulating amyotrophic lateral sclerosis.
PubMed Identifier: 12811783
author list: Vasconcelos OM, Harter DH, Duffy C, McDonough B, Seidman JG, Seidman CE, Campbell WW
published in: Muscle & nerve
information resource reference: Adult Hallervorden-Spatz syndrome simulating amyotrophic lateral sclerosis. Muscle Nerve. 2003 Jul; 28(1):118-22.
journal title abbreviation: Muscle Nerve
publication date: 2003-07-01T00:00:00
year: 2003
type: Academic Article
type: Article
type: Document
type: Information Resource

Regulation of murine fetal-placental calcium metabolism by the calcium-sensing receptor.
PubMed Identifier: 9637715
author list: Kovacs CS, Ho-Pao CL, Hunzelman JL, Lanske B, Fox J, Seidman JG, Seidman CE, Kronenberg HM
published in: The Journal of clinical investigation
information resource reference: Regulation of murine fetal-placental calcium metabolism by the calcium-sensing receptor. J Clin Invest. 1998 Jun 15; 101(12):2812-20.
journal title abbreviation: J Clin Invest
publication date: 1998-06-15T00:00:00
year: 1998
type: Academic Article
type: Article
type: Document
type: Information Resource

Altered crossbridge kinetics in the alphaMHC403/+ mouse model of familial hypertrophic cardiomyopathy.
PubMed Identifier: 10066683
author list: Blanchard E, Seidman C, Seidman JG, LeWinter M, Maughan D
published in: Circulation research
information resource reference: Altered crossbridge kinetics in the alphaMHC403/+ mouse model of familial hypertrophic cardiomyopathy. Circ Res. 1999 Mar 05; 84(4):475-83.
journal title abbreviation: Circ Res
publication date: 1999-03-05T00:00:00
year: 1999
type: Academic Article
type: Article
type: Document
type: Information Resource

Sporadic hypertrophic cardiomyopathy due to de novo myosin mutations.
PubMed Identifier: 1430197
author list: Watkins H, Thierfelder L, Hwang DS, McKenna W, Seidman JG, Seidman CE
published in: The Journal of clinical investigation
information resource reference: Sporadic hypertrophic cardiomyopathy due to de novo myosin mutations. J Clin Invest. 1992 Nov; 90(5):1666-71.
journal title abbreviation: J Clin Invest
publication date: 1992-11-01T00:00:00
year: 1992
type: Academic Article
type: Article
type: Document
type: Information Resource

Different TBX5 interactions in heart and limb defined by Holt-Oram syndrome mutations.
PubMed Identifier: 10077612
author list: Basson CT, Huang T, Lin RC, Bachinsky DR, Weremowicz S, Vaglio A, Bruzzone R, Quadrelli R, Lerone M, Romeo G, Silengo M, Pereira A, Krieger J, Mesquita SF, Kamisago M, Morton CC, Pierpont ME, Müller CW, Seidman JG, Seidman CE
published in: Proceedings of the National Academy of Sciences of the United States of America
information resource reference: Different TBX5 interactions in heart and limb defined by Holt-Oram syndrome mutations. Proc Natl Acad Sci U S A. 1999 Mar 16; 96(6):2919-24.
journal title abbreviation: Proc Natl Acad Sci U S A
publication date: 1999-03-16T00:00:00
year: 1999
type: Academic Article
type: Article
type: Document
type: Information Resource

Familial hypertrophic cardiomyopathy and atrial fibrillation caused by Arg663His beta-cardiac myosin heavy chain mutation.
PubMed Identifier: 10750581
author list: Gruver EJ, Fatkin D, Dodds GA, Kisslo J, Maron BJ, Seidman JG, Seidman CE
published in: The American journal of cardiology
information resource reference: Familial hypertrophic cardiomyopathy and atrial fibrillation caused by Arg663His beta-cardiac myosin heavy chain mutation. Am J Cardiol. 1999 Jun 17; 83(12A):13H-18H.
journal title abbreviation: Am J Cardiol
publication date: 1999-06-17T00:00:00
year: 1999
type: Academic Article
type: Article
type: Document
type: Information Resource

https://connects.catalyst.harvard.edu/Profiles/profile/794045
PubMed Identifier: 22068434
author list: Gersh BJ, Maron BJ, Bonow RO, Dearani JA, Fifer MA, Link MS, Naidu SS, Nishimura RA, Ommen SR, Rakowski H, Seidman CE, Towbin JA, Udelson JE, Yancy CW
published in: Circulation
information resource reference: 2011 ACCF/AHA guideline for the diagnosis and treatment of hypertrophic cardiomyopathy: a report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines. Circulation. 2011 Dec 13; 124(24):e783-831.
journal title abbreviation: Circulation
publication date: 2011-11-08T00:00:00
year: 2011
type: Academic Article
type: Article
type: Document
type: Information Resource
label: 2011 ACCF/AHA guideline for the diagnosis and treatment of hypertrophic cardiomyopathy: a report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines.

Biosynthesis and secretion of proatrial natriuretic factor by cultured rat cardiocytes.
PubMed Identifier: 2933808
author list: Bloch KD, Scott JA, Zisfein JB, Fallon JT, Margolies MN, Seidman CE, Matsueda GR, Homcy CJ, Graham RM, Seidman JG
published in: Science (New York, N.Y.)
information resource reference: Biosynthesis and secretion of proatrial natriuretic factor by cultured rat cardiocytes. Science. 1985 Dec 06; 230(4730):1168-71.
journal title abbreviation: Science
publication date: 1985-12-06T00:00:00
year: 1985
type: Academic Article
type: Article
type: Document
type: Information Resource

beta-Arrestin1 knockout mice appear normal but demonstrate altered cardiac responses to beta-adrenergic stimulation.
PubMed Identifier: 9400383
author list: Conner DA, Mathier MA, Mortensen RM, Christe M, Vatner SF, Seidman CE, Seidman JG
published in: Circulation research
information resource reference: beta-Arrestin1 knockout mice appear normal but demonstrate altered cardiac responses to beta-adrenergic stimulation. Circ Res. 1997 Dec; 81(6):1021-6.
journal title abbreviation: Circ Res
publication date: 1997-12-01T00:00:00
year: 1997
type: Academic Article
type: Article
type: Document
type: Information Resource

Mutations in the gene for cardiac myosin-binding protein C and late-onset familial hypertrophic cardiomyopathy.
PubMed Identifier: 9562578
author list: Niimura H, Bachinski LL, Sangwatanaroj S, Watkins H, Chudley AE, McKenna W, Kristinsson A, Roberts R, Sole M, Maron BJ, Seidman JG, Seidman CE
published in: The New England journal of medicine
information resource reference: Mutations in the gene for cardiac myosin-binding protein C and late-onset familial hypertrophic cardiomyopathy. N Engl J Med. 1998 Apr 30; 338(18):1248-57.
journal title abbreviation: N Engl J Med
publication date: 1998-04-30T00:00:00
year: 1998
type: Academic Article
type: Article
type: Document
type: Information Resource

Dilated cardiomyopathy in homozygous myosin-binding protein-C mutant mice.
PubMed Identifier: 10545522
author list: McConnell BK, Jones KA, Fatkin D, Arroyo LH, Lee RT, Aristizabal O, Turnbull DH, Georgakopoulos D, Kass D, Bond M, Niimura H, Schoen FJ, Conner D, Fischman DA, Seidman CE, Seidman JG, Fischman DH
published in: The Journal of clinical investigation
information resource reference: Dilated cardiomyopathy in homozygous myosin-binding protein-C mutant mice. J Clin Invest. 1999 Nov; 104(9):1235-44.
journal title abbreviation: J Clin Invest
publication date: 1999-11-01T00:00:00
year: 1999
type: Academic Article
type: Article
type: Document
type: Information Resource

Cardiac expression of the ventricle-specific homeobox gene Irx4 is modulated by Nkx2-5 and dHand.
PubMed Identifier: 10625552
author list: Bruneau BG, Bao ZZ, Tanaka M, Schott JJ, Izumo S, Cepko CL, Seidman JG, Seidman CE
published in: Developmental biology
information resource reference: Cardiac expression of the ventricle-specific homeobox gene Irx4 is modulated by Nkx2-5 and dHand. Dev Biol. 2000 Jan 15; 217(2):266-77.
journal title abbreviation: Dev Biol
publication date: 2000-01-15T00:00:00
year: 2000
type: Academic Article
type: Article
type: Document
type: Information Resource

Relationship between carbohydrate-induced hypertriglyceridemia and fatty acid synthesis in lean and obese subjects.
PubMed Identifier: 10744780
author list: Hudgins LC, Hellerstein MK, Seidman CE, Neese RA, Tremaroli JD, Hirsch J
published in: Journal of lipid research
information resource reference: Relationship between carbohydrate-induced hypertriglyceridemia and fatty acid synthesis in lean and obese subjects. J Lipid Res. 2000 Apr; 41(4):595-604.
journal title abbreviation: J Lipid Res
publication date: 2000-04-01T00:00:00
year: 2000
type: Academic Article
type: Article
type: Document
type: Information Resource

Dilated cardiomyopathy and heart failure caused by a mutation in phospholamban.
PubMed Identifier: 12610310
author list: Schmitt JP, Kamisago M, Asahi M, Li GH, Ahmad F, Mende U, Kranias EG, MacLennan DH, Seidman JG, Seidman CE
published in: Science (New York, N.Y.)
information resource reference: Dilated cardiomyopathy and heart failure caused by a mutation in phospholamban. Science. 2003 Feb 28; 299(5611):1410-3.
journal title abbreviation: Science
publication date: 2003-02-28T00:00:00
year: 2003
type: Academic Article
type: Article
type: Document
type: Information Resource

Role of cardiac myosin binding protein C in sustaining left ventricular systolic stiffening.
PubMed Identifier: 15059932
author list: Palmer BM, Georgakopoulos D, Janssen PM, Wang Y, Alpert NR, Belardi DF, Harris SP, Moss RL, Burgon PG, Seidman CE, Seidman JG, Maughan DW, Kass DA
published in: Circulation research
information resource reference: Role of cardiac myosin binding protein C in sustaining left ventricular systolic stiffening. Circ Res. 2004 May 14; 94(9):1249-55.
journal title abbreviation: Circ Res
publication date: 2004-04-01T00:00:00
year: 2004
type: Academic Article
type: Article
type: Document
type: Information Resource

An abnormal Ca(2+) response in mutant sarcomere protein-mediated familial hypertrophic cardiomyopathy.
PubMed Identifier: 11104788
author list: Fatkin D, McConnell BK, Mudd JO, Semsarian C, Moskowitz IG, Schoen FJ, Giewat M, Seidman CE, Seidman JG
published in: The Journal of clinical investigation
information resource reference: An abnormal Ca(2+) response in mutant sarcomere protein-mediated familial hypertrophic cardiomyopathy. J Clin Invest. 2000 Dec; 106(11):1351-9.
journal title abbreviation: J Clin Invest
publication date: 2000-12-01T00:00:00
year: 2000
type: Academic Article
type: Article
type: Document
type: Information Resource

Cardiomyopathy in Irx4-deficient mice is preceded by abnormal ventricular gene expression.
PubMed Identifier: 11238910
author list: Bruneau BG, Bao ZZ, Fatkin D, Xavier-Neto J, Georgakopoulos D, Maguire CT, Berul CI, Kass DA, Kuroski-de Bold ML, de Bold AJ, Conner DA, Rosenthal N, Cepko CL, Seidman CE, Seidman JG
published in: Molecular and cellular biology
information resource reference: Cardiomyopathy in Irx4-deficient mice is preceded by abnormal ventricular gene expression. Mol Cell Biol. 2001 Mar; 21(5):1730-6.
journal title abbreviation: Mol Cell Biol
publication date: 2001-03-01T00:00:00
year: 2001
type: Academic Article
type: Article
type: Document
type: Information Resource

The coming of age of cardiovascular science.
PubMed Identifier: 12858581
author list: Seidman CE, Seidman JG
published in: Cold Spring Harbor symposia on quantitative biology
information resource reference: The coming of age of cardiovascular science. Cold Spring Harb Symp Quant Biol. 2002; 67:543-50.
journal title abbreviation: Cold Spring Harb Symp Quant Biol
publication date: 2002-01-01T00:00:00
year: 2002
type: Academic Article
type: Article
type: Document
type: Information Resource

Alpha 1-adrenergic receptor mRNA level is regulated by norepinephrine in rabbit aortic smooth muscle cells.
PubMed Identifier: 2166953
author list: Izzo NJ, Seidman CE, Collins S, Colucci WS
published in: Proceedings of the National Academy of Sciences of the United States of America
information resource reference: Alpha 1-adrenergic receptor mRNA level is regulated by norepinephrine in rabbit aortic smooth muscle cells. Proc Natl Acad Sci U S A. 1990 Aug; 87(16):6268-71.
journal title abbreviation: Proc Natl Acad Sci U S A
publication date: 1990-08-01T00:00:00
year: 1990
type: Academic Article
type: Article
type: Document
type: Information Resource

Transgenic mice overexpressing mutant PRKAG2 define the cause of Wolff-Parkinson-White syndrome in glycogen storage cardiomyopathy.
PubMed Identifier: 12782567
author list: Arad M, Moskowitz IP, Patel VV, Ahmad F, Perez-Atayde AR, Sawyer DB, Walter M, Li GH, Burgon PG, Maguire CT, Stapleton D, Schmitt JP, Guo XX, Pizard A, Kupershmidt S, Roden DM, Berul CI, Seidman CE, Seidman JG
published in: Circulation
information resource reference: Transgenic mice overexpressing mutant PRKAG2 define the cause of Wolff-Parkinson-White syndrome in glycogen storage cardiomyopathy. Circulation. 2003 Jun 10; 107(22):2850-6.
journal title abbreviation: Circulation
publication date: 2003-06-02T00:00:00
year: 2003
type: Academic Article
type: Article
type: Document
type: Information Resource

Familial dilated cardiomyopathy caused by an alpha-tropomyosin mutation: the distinctive natural history of sarcomeric dilated cardiomyopathy.
PubMed Identifier: 20117437
author list: Lakdawala NK, Dellefave L, Redwood CS, Sparks E, Cirino AL, Depalma S, Colan SD, Funke B, Zimmerman RS, Robinson P, Watkins H, Seidman CE, Seidman JG, McNally EM, Ho CY
published in: Journal of the American College of Cardiology
information resource reference: Familial dilated cardiomyopathy caused by an alpha-tropomyosin mutation: the distinctive natural history of sarcomeric dilated cardiomyopathy. J Am Coll Cardiol. 2010 Jan 26; 55(4):320-9.
journal title abbreviation: J Am Coll Cardiol
publication date: 2010-01-26T00:00:00
year: 2010
type: Academic Article
type: Article
type: Document
type: Information Resource

Phenotypic diversity in hypertrophic cardiomyopathy.
PubMed Identifier: 12351586
author list: Arad M, Seidman JG, Seidman CE
published in: Human molecular genetics
information resource reference: Phenotypic diversity in hypertrophic cardiomyopathy. Hum Mol Genet. 2002 Oct 01; 11(20):2499-506.
journal title abbreviation: Hum Mol Genet
publication date: 2002-10-01T00:00:00
year: 2002
type: Academic Article
type: Article
type: Document
type: Information Resource

https://connects.catalyst.harvard.edu/Profiles/profile/818427
PubMed Identifier: 14585256
author list: Maron BJ, McKenna WJ, Danielson GK, Kappenberger LJ, Kuhn HJ, Seidman CE, Shah PM, Spencer WH, Spirito P, Ten Cate FJ, Wigle ED
published in: European heart journal
information resource reference: American College of Cardiology/European Society of Cardiology Clinical Expert Consensus Document on Hypertrophic Cardiomyopathy. A report of the American College of Cardiology Foundation Task Force on Clinical Expert Consensus Documents and the European Society of Cardiology Committee for Practice Guidelines. Eur Heart J. 2003 Nov; 24(21):1965-91.
journal title abbreviation: Eur Heart J
publication date: 2003-11-01T00:00:00
year: 2003
type: Academic Article
type: Article
type: Document
type: Information Resource
label: American College of Cardiology/European Society of Cardiology Clinical Expert Consensus Document on Hypertrophic Cardiomyopathy. A report of the American College of Cardiology Foundation Task Force on Clinical Expert Consensus Documents and the European Society of Cardiology Committee for Practice Guidelines.

Effect of cardiac myosin binding protein-C on mechanoenergetics in mouse myocardium.
PubMed Identifier: 15155526
author list: Palmer BM, Noguchi T, Wang Y, Heim JR, Alpert NR, Burgon PG, Seidman CE, Seidman JG, Maughan DW, LeWinter MM
published in: Circulation research
information resource reference: Effect of cardiac myosin binding protein-C on mechanoenergetics in mouse myocardium. Circ Res. 2004 Jun 25; 94(12):1615-22.
journal title abbreviation: Circ Res
publication date: 2004-05-20T00:00:00
year: 2004
type: Academic Article
type: Article
type: Document
type: Information Resource

N488I mutation of the gamma2-subunit results in bidirectional changes in AMP-activated protein kinase activity.
PubMed Identifier: 16051890
author list: Zou L, Shen M, Arad M, He H, Løfgren B, Ingwall JS, Seidman CE, Seidman JG, Tian R
published in: Circulation research
information resource reference: N488I mutation of the gamma2-subunit results in bidirectional changes in AMP-activated protein kinase activity. Circ Res. 2005 Aug 19; 97(4):323-8.
journal title abbreviation: Circ Res
publication date: 2005-07-28T00:00:00
year: 2005
type: Academic Article
type: Article
type: Document
type: Information Resource

Connexin 40, a target of transcription factor Tbx5, patterns wrist, digits, and sternum.
PubMed Identifier: 15923624
author list: Pizard A, Burgon PG, Paul DL, Bruneau BG, Seidman CE, Seidman JG
published in: Molecular and cellular biology
information resource reference: Connexin 40, a target of transcription factor Tbx5, patterns wrist, digits, and sternum. Mol Cell Biol. 2005 Jun; 25(12):5073-83.
journal title abbreviation: Mol Cell Biol
publication date: 2005-06-01T00:00:00
year: 2005
type: Academic Article
type: Article
type: Document
type: Information Resource

https://connects.catalyst.harvard.edu/Profiles/profile/823399
PubMed Identifier: 22093712
author list: Gersh BJ, Maron BJ, Bonow RO, Dearani JA, Fifer MA, Link MS, Naidu SS, Nishimura RA, Ommen SR, Rakowski H, Seidman CE, Towbin JA, Udelson JE, Yancy CW
published in: The Journal of thoracic and cardiovascular surgery
information resource reference: 2011 ACCF/AHA guideline for the diagnosis and treatment of hypertrophic cardiomyopathy: executive summary: a report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines. J Thorac Cardiovasc Surg. 2011 Dec; 142(6):1303-38.
journal title abbreviation: J Thorac Cardiovasc Surg
publication date: 2011-12-01T00:00:00
year: 2011
type: Academic Article
type: Article
type: Document
type: Information Resource
label: 2011 ACCF/AHA guideline for the diagnosis and treatment of hypertrophic cardiomyopathy: executive summary: a report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines.

Sudden death due to troponin T mutations.
PubMed Identifier: 9060892
author list: Moolman JC, Corfield VA, Posen B, Ngumbela K, Seidman C, Brink PA, Watkins H
published in: Journal of the American College of Cardiology
information resource reference: Sudden death due to troponin T mutations. J Am Coll Cardiol. 1997 Mar 01; 29(3):549-55.
journal title abbreviation: J Am Coll Cardiol
publication date: 1997-03-01T00:00:00
year: 1997
type: Academic Article
type: Article
type: Document
type: Information Resource

Familial hypertrophic cardiomyopathy mice display gender differences in electrophysiological abnormalities.
PubMed Identifier: 9869991
author list: Berul CI, Christe ME, Aronovitz MJ, Maguire CT, Seidman CE, Seidman JG, Mendelsohn ME
published in: Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing
information resource reference: Familial hypertrophic cardiomyopathy mice display gender differences in electrophysiological abnormalities. J Interv Card Electrophysiol. 1998 Mar; 2(1):7-14.
journal title abbreviation: J Interv Card Electrophysiol
publication date: 1998-03-01T00:00:00
year: 1998
type: Academic Article
type: Article
type: Document
type: Information Resource

Neonatal cardiomyopathy in mice homozygous for the Arg403Gln mutation in the alpha cardiac myosin heavy chain gene.
PubMed Identifier: 9884344
author list: Fatkin D, Christe ME, Aristizabal O, McConnell BK, Srinivasan S, Schoen FJ, Seidman CE, Turnbull DH, Seidman JG
published in: The Journal of clinical investigation
information resource reference: Neonatal cardiomyopathy in mice homozygous for the Arg403Gln mutation in the alpha cardiac myosin heavy chain gene. J Clin Invest. 1999 Jan; 103(1):147-53.
journal title abbreviation: J Clin Invest
publication date: 1999-01-01T00:00:00
year: 1999
type: Academic Article
type: Article
type: Document
type: Information Resource

Cardiac myosin binding protein C phosphorylation is cardioprotective.
PubMed Identifier: 17075052
author list: Sadayappan S, Osinska H, Klevitsky R, Lorenz JN, Sargent M, Molkentin JD, Seidman CE, Seidman JG, Robbins J
published in: Proceedings of the National Academy of Sciences of the United States of America
information resource reference: Cardiac myosin binding protein C phosphorylation is cardioprotective. Proc Natl Acad Sci U S A. 2006 Nov 07; 103(45):16918-23.
journal title abbreviation: Proc Natl Acad Sci U S A
publication date: 2006-10-30T00:00:00
year: 2006
type: Academic Article
type: Article
type: Document
type: Information Resource

Calsequestrin 2 (CASQ2) mutations increase expression of calreticulin and ryanodine receptors, causing catecholaminergic polymorphic ventricular tachycardia.
PubMed Identifier: 17607358
author list: Song L, Alcalai R, Arad M, Wolf CM, Toka O, Conner DA, Berul CI, Eldar M, Seidman CE, Seidman JG
published in: The Journal of clinical investigation
information resource reference: Calsequestrin 2 (CASQ2) mutations increase expression of calreticulin and ryanodine receptors, causing catecholaminergic polymorphic ventricular tachycardia. J Clin Invest. 2007 Jul; 117(7):1814-23.
journal title abbreviation: J Clin Invest
publication date: 2007-07-01T00:00:00
year: 2007
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 987966
type: Authorship
author rank in publication: 16
linked author: Seidman, Christine
linked information resource: Cardiac Myosin Binding Protein-C Autoantibodies are Potential Early Indicators of Cardiac Dysfunction and Patient Outcome in Acute Coronary Syndrome.

Cardiac Myosin Binding Protein-C Autoantibodies are Potential Early Indicators of Cardiac Dysfunction and Patient Outcome in Acute Coronary Syndrome.
PubMed Identifier: 28596995
author list: Lynch TL, Kuster DWD, Gonzalez B, Balasubramanian N, Nair N, Day S, Calvino JE, Tan Y, Liebetrau C, Troidl C, Hamm CW, Güçlü A, McDonough B, Marian AJ, van der Velden J, Seidman CE, Huggins GS, Sadayappan S
published in: JACC. Basic to translational science
information resource reference: Cardiac Myosin Binding Protein-C Autoantibodies are Potential Early Indicators of Cardiac Dysfunction and Patient Outcome in Acute Coronary Syndrome. JACC Basic Transl Sci. 2017 Apr; 2(2):122-131.
journal title abbreviation: JACC Basic Transl Sci
publication date: 2016-12-19T00:00:00
year: 2016
type: Academic Article
type: Article
type: Document
type: Information Resource

Proposal for contemporary screening strategies in families with hypertrophic cardiomyopathy.
PubMed Identifier: 15582308
author list: Maron BJ, Seidman JG, Seidman CE
published in: Journal of the American College of Cardiology
information resource reference: Proposal for contemporary screening strategies in families with hypertrophic cardiomyopathy. J Am Coll Cardiol. 2004 Dec 07; 44(11):2125-32.
journal title abbreviation: J Am Coll Cardiol
publication date: 2004-12-07T00:00:00
year: 2004
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 988934
type: Authorship
author rank in publication: 18
linked author: Seidman, Christine
linked information resource: Integrative Analysis of PRKAG2 Cardiomyopathy iPS and Microtissue Models Identifies AMPK as a Regulator of Metabolism, Survival, and Fibrosis.

Authorship 989994
type: Authorship
author rank in publication: 6
linked author: Seidman, Christine
linked information resource: Effects of myosin variants on interacting-heads motif explain distinct hypertrophic and dilated cardiomyopathy phenotypes.

Effects of myosin variants on interacting-heads motif explain distinct hypertrophic and dilated cardiomyopathy phenotypes.
PubMed Identifier: 28606303
author list: Alamo L, Ware JS, Pinto A, Gillilan RE, Seidman JG, Seidman CE, Padrón R
published in: eLife
information resource reference: Effects of myosin variants on interacting-heads motif explain distinct hypertrophic and dilated cardiomyopathy phenotypes. Elife. 2017 06 13; 6.
journal title abbreviation: Elife
publication date: 2017-06-13T00:00:00
year: 2017
type: Academic Article
type: Article
type: Document
type: Information Resource

Integrative Analysis of PRKAG2 Cardiomyopathy iPS and Microtissue Models Identifies AMPK as a Regulator of Metabolism, Survival, and Fibrosis.
PubMed Identifier: 28614725
author list: Hinson JT, Chopra A, Lowe A, Sheng CC, Gupta RM, Kuppusamy R, O'Sullivan J, Rowe G, Wakimoto H, Gorham J, Burke MA, Zhang K, Musunuru K, Gerszten RE, Wu SM, Chen CS, Seidman JG, Seidman CE
published in: Cell reports
information resource reference: Integrative Analysis of PRKAG2 Cardiomyopathy iPS and Microtissue Models Identifies AMPK as a Regulator of Metabolism, Survival, and Fibrosis. Cell Rep. 2017 06 13; 19(11):2410.
journal title abbreviation: Cell Rep
publication date: 2017-06-13T00:00:00
year: 2017
type: Academic Article
type: Article
type: Document
type: Information Resource

Lamin A/C haploinsufficiency causes dilated cardiomyopathy and apoptosis-triggered cardiac conduction system disease.
PubMed Identifier: 18182166
author list: Wolf CM, Wang L, Alcalai R, Pizard A, Burgon PG, Ahmad F, Sherwood M, Branco DM, Wakimoto H, Fishman GI, See V, Stewart CL, Conner DA, Berul CI, Seidman CE, Seidman JG
published in: Journal of molecular and cellular cardiology
information resource reference: Lamin A/C haploinsufficiency causes dilated cardiomyopathy and apoptosis-triggered cardiac conduction system disease. J Mol Cell Cardiol. 2008 Feb; 44(2):293-303.
journal title abbreviation: J Mol Cell Cardiol
publication date: 2007-12-03T00:00:00
year: 2007
type: Academic Article
type: Article
type: Document
type: Information Resource

Increased glycogen stores due to gamma-AMPK overexpression protects against ischemia and reperfusion damage.
PubMed Identifier: 18261713
author list: Ofir M, Arad M, Porat E, Freimark D, Chepurko Y, Vidne BA, Seidman CE, Seidman JG, Kemp BE, Hochhauser E
published in: Biochemical pharmacology
information resource reference: Increased glycogen stores due to gamma-AMPK overexpression protects against ischemia and reperfusion damage. Biochem Pharmacol. 2008 Apr 01; 75(7):1482-91.
journal title abbreviation: Biochem Pharmacol
publication date: 2008-01-05T00:00:00
year: 2008
type: Academic Article
type: Article
type: Document
type: Information Resource

Myofilament mechanical performance is enhanced by R403Q myosin in mouse myocardium independent of sex.
PubMed Identifier: 18281382
author list: Palmer BM, Wang Y, Teekakirikul P, Hinson JT, Fatkin D, Strouse S, Vanburen P, Seidman CE, Seidman JG, Maughan DW
published in: American journal of physiology. Heart and circulatory physiology
information resource reference: Myofilament mechanical performance is enhanced by R403Q myosin in mouse myocardium independent of sex. Am J Physiol Heart Circ Physiol. 2008 Apr; 294(4):H1939-47.
journal title abbreviation: Am J Physiol Heart Circ Physiol
publication date: 2008-02-15T00:00:00
year: 2008
type: Academic Article
type: Article
type: Document
type: Information Resource

A locus for inherited focal segmental glomerulosclerosis maps to chromosome 19q13.
PubMed Identifier: 9461087
author list: Mathis BJ, Kim SH, Calabrese K, Haas M, Seidman JG, Seidman CE, Pollak MR
published in: Kidney international
information resource reference: A locus for inherited focal segmental glomerulosclerosis maps to chromosome 19q13. Kidney Int. 1998 Feb; 53(2):282-6.
journal title abbreviation: Kidney Int
publication date: 1998-02-01T00:00:00
year: 1998
type: Academic Article
type: Article
type: Document
type: Information Resource

Causes of clinical diversity in human TBX5 mutations.
PubMed Identifier: 12858531
author list: Huang T, Lock JE, Marshall AC, Basson C, Seidman JG, Seidman CE
published in: Cold Spring Harbor symposia on quantitative biology
information resource reference: Causes of clinical diversity in human TBX5 mutations. Cold Spring Harb Symp Quant Biol. 2002; 67:115-20.
journal title abbreviation: Cold Spring Harb Symp Quant Biol
publication date: 2002-01-01T00:00:00
year: 2002
type: Academic Article
type: Article
type: Document
type: Information Resource

Progress in familial hypertrophic cardiomyopathy: molecular genetic analyses in the original family studied by Teare.
PubMed Identifier: 1739523
author list: Watkins H, Seidman CE, MacRae C, Seidman JG, McKenna W
published in: British heart journal
information resource reference: Progress in familial hypertrophic cardiomyopathy: molecular genetic analyses in the original family studied by Teare. Br Heart J. 1992 Jan; 67(1):34-8.
journal title abbreviation: Br Heart J
publication date: 1992-01-01T00:00:00
year: 1992
type: Academic Article
type: Article
type: Document
type: Information Resource

Burden of rare sarcomere gene variants in the Framingham and Jackson Heart Study cohorts.
PubMed Identifier: 22958901
author list: Bick AG, Flannick J, Ito K, Cheng S, Vasan RS, Parfenov MG, Herman DS, DePalma SR, Gupta N, Gabriel SB, Funke BH, Rehm HL, Benjamin EJ, Aragam J, Taylor HA, Fox ER, Newton-Cheh C, Kathiresan S, O'Donnell CJ, Wilson JG, Altshuler DM, Hirschhorn JN, Seidman JG, Seidman C
published in: American journal of human genetics
information resource reference: Burden of rare sarcomere gene variants in the Framingham and Jackson Heart Study cohorts. Am J Hum Genet. 2012 Sep 07; 91(3):513-9.
journal title abbreviation: Am J Hum Genet
publication date: 2012-09-07T00:00:00
year: 2012
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 993094
type: Authorship
author rank in publication: 10
linked author: Seidman, Christine
linked information resource: Fundamental Cardiovascular Research: Returns on Societal Investment: A Scientific Statement From the American Heart Association.

Fundamental Cardiovascular Research: Returns on Societal Investment: A Scientific Statement From the American Heart Association.
PubMed Identifier: 28652256
author list: Hill JA, Ardehali R, Clarke KT, Del Zoppo GJ, Eckhardt LL, Griendling KK, Libby P, Roden DM, Sadek HA, Seidman CE, Vaughan DE
published in: Circulation research
information resource reference: Fundamental Cardiovascular Research: Returns on Societal Investment: A Scientific Statement From the American Heart Association. Circ Res. 2017 Jul 21; 121(3):e2-e8.
journal title abbreviation: Circ Res
publication date: 2017-06-26T00:00:00
year: 2017
type: Academic Article
type: Article
type: Document
type: Information Resource

Elevated rates of force development and MgATP binding in F764L and S532P myosin mutations causing dilated cardiomyopathy.
PubMed Identifier: 23313350
author list: Palmer BM, Schmitt JP, Seidman CE, Seidman JG, Wang Y, Bell SP, Lewinter MM, Maughan DW
published in: Journal of molecular and cellular cardiology
information resource reference: Elevated rates of force development and MgATP binding in F764L and S532P myosin mutations causing dilated cardiomyopathy. J Mol Cell Cardiol. 2013 Apr; 57:23-31.
journal title abbreviation: J Mol Cell Cardiol
publication date: 2013-01-08T00:00:00
year: 2013
type: Academic Article
type: Article
type: Document
type: Information Resource

Dissection of chromosome 18 blood pressure and salt-sensitivity quantitative trait loci in the spontaneously hypertensive rat.
PubMed Identifier: 19620519
author list: Johnson MD, He L, Herman D, Wakimoto H, Wallace CA, Zidek V, Mlejnek P, Musilova A, Simakova M, Vorlicek J, Kren V, Viklicky O, Qi NR, Wang J, Seidman CE, Seidman J, Kurtz TW, Aitman TJ, Pravenec M
published in: Hypertension (Dallas, Tex. : 1979)
information resource reference: Dissection of chromosome 18 blood pressure and salt-sensitivity quantitative trait loci in the spontaneously hypertensive rat. Hypertension. 2009 Sep; 54(3):639-45.
journal title abbreviation: Hypertension
publication date: 2009-07-20T00:00:00
year: 2009
type: Academic Article
type: Article
type: Document
type: Information Resource

Molecular studies of the atrial natriuretic factor gene.
PubMed Identifier: 3158606
author list: Seidman CE, Bloch KD, Zisfein J, Smith JA, Haber E, Homcy C, Duby AD, Choi E, Graham RM, Seidman JG
published in: Hypertension (Dallas, Tex. : 1979)
information resource reference: Molecular studies of the atrial natriuretic factor gene. Hypertension. 1985 May-Jun; 7(3 Pt 2):I31-4.
journal title abbreviation: Hypertension
publication date: 1985-05-01T00:00:00
year: 1985
type: Academic Article
type: Article
type: Document
type: Information Resource

Glycogen storage diseases presenting as hypertrophic cardiomyopathy.
PubMed Identifier: 15673802
author list: Arad M, Maron BJ, Gorham JM, Johnson WH, Saul JP, Perez-Atayde AR, Spirito P, Wright GB, Kanter RJ, Seidman CE, Seidman JG
published in: The New England journal of medicine
information resource reference: Glycogen storage diseases presenting as hypertrophic cardiomyopathy. N Engl J Med. 2005 Jan 27; 352(4):362-72.
journal title abbreviation: N Engl J Med
publication date: 2005-01-27T00:00:00
year: 2005
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 996811
type: Authorship
author rank in publication: 7
linked author: Seidman, Christine
linked information resource: Joint analysis of left ventricular expression and circulating plasma levels of Omentin after myocardial ischemia.

Authorship 997807
type: Authorship
author rank in publication: 11
linked author: Seidman, Christine
linked information resource: Identification of pathogenic gene mutations in LMNA and MYBPC3 that alter RNA splicing.

Joint analysis of left ventricular expression and circulating plasma levels of Omentin after myocardial ischemia.
PubMed Identifier: 28687077
author list: Saddic LA, Nicoloro SM, Gupta OT, Czech MP, Gorham J, Shernan SK, Seidman CE, Seidman JG, Aranki SF, Body SC, Fitzgibbons TP, Muehlschlegel JD
published in: Cardiovascular diabetology
information resource reference: Joint analysis of left ventricular expression and circulating plasma levels of Omentin after myocardial ischemia. Cardiovasc Diabetol. 2017 07 07; 16(1):87.
journal title abbreviation: Cardiovasc Diabetol
publication date: 2017-07-07T00:00:00
year: 2017
type: Academic Article
type: Article
type: Document
type: Information Resource

Identification of pathogenic gene mutations in LMNA and MYBPC3 that alter RNA splicing.
PubMed Identifier: 28679633
author list: Ito K, Patel PN, Gorham JM, McDonough B, DePalma SR, Adler EE, Lam L, MacRae CA, Mohiuddin SM, Fatkin D, Seidman CE, Seidman JG
published in: Proceedings of the National Academy of Sciences of the United States of America
information resource reference: Identification of pathogenic gene mutations in LMNA and MYBPC3 that alter RNA splicing. Proc Natl Acad Sci U S A. 2017 07 18; 114(29):7689-7694.
journal title abbreviation: Proc Natl Acad Sci U S A
publication date: 2017-07-05T00:00:00
year: 2017
type: Academic Article
type: Article
type: Document
type: Information Resource

T cell responses in calcineurin A alpha-deficient mice.
PubMed Identifier: 8627154
author list: Zhang BW, Zimmer G, Chen J, Ladd D, Li E, Alt FW, Wiederrecht G, Cryan J, O'Neill EA, Seidman CE, Abbas AK, Seidman JG
published in: The Journal of experimental medicine
information resource reference: T cell responses in calcineurin A alpha-deficient mice. J Exp Med. 1996 Feb 01; 183(2):413-20.
journal title abbreviation: J Exp Med
publication date: 1996-02-01T00:00:00
year: 1996
type: Academic Article
type: Article
type: Document
type: Information Resource

Reduced cross-bridge dependent stiffness of skinned myocardium from mice lacking cardiac myosin binding protein-C.
PubMed Identifier: 15524168
author list: Palmer BM, McConnell BK, Li GH, Seidman CE, Seidman JG, Irving TC, Alpert NR, Maughan DW
published in: Molecular and cellular biochemistry
information resource reference: Reduced cross-bridge dependent stiffness of skinned myocardium from mice lacking cardiac myosin binding protein-C. Mol Cell Biochem. 2004 Aug; 263(1-2):73-80.
journal title abbreviation: Mol Cell Biochem
publication date: 2004-08-01T00:00:00
year: 2004
type: Academic Article
type: Article
type: Document
type: Information Resource

77 Avenue Louis Pasteur
type: Address
address line 1: Harvard Medical School
address line 2: Dept. Genetics, NRB-256
address line 3: 77 Avenue Louis Pasteur
city: Boston
postal code: 02115
state or province: MA

Introduction of plasmid DNA into cells.
PubMed Identifier: 18265047
author list: Seidman CE, Struhl K, Sheen J, Jessen T
published in: Current protocols in molecular biology
information resource reference: Introduction of plasmid DNA into cells. Curr Protoc Mol Biol. 2001 May; Chapter 1:Unit1.8.
journal title abbreviation: Curr Protoc Mol Biol
publication date: 2001-05-01T00:00:00
year: 2001
type: Academic Article
type: Article
type: Document
type: Information Resource

Cloning and functional characterization of extracellular Ca(2+)-sensing receptors from parathyroid and kidney.
PubMed Identifier: 8579901
author list: Brown EM, Pollak M, Chou YH, Seidman CE, Seidman JG, Hebert SC
published in: Bone
information resource reference: Cloning and functional characterization of extracellular Ca(2+)-sensing receptors from parathyroid and kidney. Bone. 1995 Aug; 17(2 Suppl):7S-11S.
journal title abbreviation: Bone
publication date: 1995-08-01T00:00:00
year: 1995
type: Academic Article
type: Article
type: Document
type: Information Resource

Missense mutation in the pore region of HERG causes familial long QT syndrome.
PubMed Identifier: 8635257
author list: Benson DW, MacRae CA, Vesely MR, Walsh EP, Seidman JG, Seidman CE, Satler CA
published in: Circulation
information resource reference: Missense mutation in the pore region of HERG causes familial long QT syndrome. Circulation. 1996 May 15; 93(10):1791-5.
journal title abbreviation: Circulation
publication date: 1996-05-15T00:00:00
year: 1996
type: Academic Article
type: Article
type: Document
type: Information Resource

Aberrant activation of AMP-activated protein kinase remodels metabolic network in favor of cardiac glycogen storage.
PubMed Identifier: 17431505
author list: Luptak I, Shen M, He H, Hirshman MF, Musi N, Goodyear LJ, Yan J, Wakimoto H, Morita H, Arad M, Seidman CE, Seidman JG, Ingwall JS, Balschi JA, Tian R
published in: The Journal of clinical investigation
information resource reference: Aberrant activation of AMP-activated protein kinase remodels metabolic network in favor of cardiac glycogen storage. J Clin Invest. 2007 May; 117(5):1432-9.
journal title abbreviation: J Clin Invest
publication date: 2007-04-12T00:00:00
year: 2007
type: Academic Article
type: Article
type: Document
type: Information Resource

Severe heart failure and early mortality in a double-mutation mouse model of familial hypertrophic cardiomyopathy.
PubMed Identifier: 18362229
author list: Tsoutsman T, Kelly M, Ng DC, Tan JE, Tu E, Lam L, Bogoyevitch MA, Seidman CE, Seidman JG, Semsarian C
published in: Circulation
information resource reference: Severe heart failure and early mortality in a double-mutation mouse model of familial hypertrophic cardiomyopathy. Circulation. 2008 Apr 08; 117(14):1820-31.
journal title abbreviation: Circulation
publication date: 2008-03-24T00:00:00
year: 2008
type: Academic Article
type: Article
type: Document
type: Information Resource

HLA and other immunogenetic approaches to the study of diseases in man.
PubMed Identifier: 324531
author list: Levis WR, Seidman CE
published in: Biomedicine / [publiee pour l'A.A.I.C.I.G.]
information resource reference: HLA and other immunogenetic approaches to the study of diseases in man. Biomedicine. 1977 Feb; 26(1):5-8.
journal title abbreviation: Biomedicine
publication date: 1977-02-01T00:00:00
year: 1977
type: Academic Article
type: Article
type: Document
type: Information Resource

Transcription factor genes Smad4 and Gata4 cooperatively regulate cardiac valve development. [corrected]
PubMed Identifier: 21330551
author list: Moskowitz IP, Wang J, Peterson MA, Pu WT, Mackinnon AC, Oxburgh L, Chu GC, Sarkar M, Berul C, Smoot L, Robertson EJ, Schwartz R, Seidman JG, Seidman CE
published in: Proceedings of the National Academy of Sciences of the United States of America
information resource reference: Transcription factor genes Smad4 and Gata4 cooperatively regulate cardiac valve development. [corrected] Proc Natl Acad Sci U S A. 2011 Mar 08; 108(10):4006-11.
journal title abbreviation: Proc Natl Acad Sci U S A
publication date: 2011-02-17T00:00:00
year: 2011
type: Academic Article
type: Article
type: Document
type: Information Resource

Mapping a gene for familial hypertrophic cardiomyopathy to chromosome 14q1.
PubMed Identifier: 2811944
author list: Jarcho JA, McKenna W, Pare JA, Solomon SD, Holcombe RF, Dickie S, Levi T, Donis-Keller H, Seidman JG, Seidman CE
published in: The New England journal of medicine
information resource reference: Mapping a gene for familial hypertrophic cardiomyopathy to chromosome 14q1. N Engl J Med. 1989 Nov 16; 321(20):1372-8.
journal title abbreviation: N Engl J Med
publication date: 1989-11-16T00:00:00
year: 1989
type: Academic Article
type: Article
type: Document
type: Information Resource

Comparison of two murine models of familial hypertrophic cardiomyopathy.
PubMed Identifier: 11230104
author list: McConnell BK, Fatkin D, Semsarian C, Jones KA, Georgakopoulos D, Maguire CT, Healey MJ, Mudd JO, Moskowitz IP, Conner DA, Giewat M, Wakimoto H, Berul CI, Schoen FJ, Kass DA, Seidman CE, Seidman JG
published in: Circulation research
information resource reference: Comparison of two murine models of familial hypertrophic cardiomyopathy. Circ Res. 2001 Mar 02; 88(4):383-9.
journal title abbreviation: Circ Res
publication date: 2001-03-02T00:00:00
year: 2001
type: Academic Article
type: Article
type: Document
type: Information Resource

Atrial natriuretic factor: assessment of its structure in atria and regulation of its biosynthesis with volume depletion.
PubMed Identifier: 2946873
author list: Zisfein JB, Matsueda GR, Fallon JT, Bloch KD, Seidman CE, Seidman JG, Homcy CJ, Graham RM
published in: Journal of molecular and cellular cardiology
information resource reference: Atrial natriuretic factor: assessment of its structure in atria and regulation of its biosynthesis with volume depletion. J Mol Cell Cardiol. 1986 Sep; 18(9):917-29.
journal title abbreviation: J Mol Cell Cardiol
publication date: 1986-09-01T00:00:00
year: 1986
type: Academic Article
type: Article
type: Document
type: Information Resource

Genetics of congenital heart disease: the glass half empty.
PubMed Identifier: 23410880
author list: Fahed AC, Gelb BD, Seidman JG, Seidman CE
published in: Circulation research
information resource reference: Genetics of congenital heart disease: the glass half empty. Circ Res. 2013 Feb 15; 112(4):707-20.
journal title abbreviation: Circ Res
publication date: 2013-02-15T00:00:00
year: 2013
type: Academic Article
type: Article
type: Document
type: Information Resource

A novel custom resequencing array for dilated cardiomyopathy.
PubMed Identifier: 20474083
author list: Zimmerman RS, Cox S, Lakdawala NK, Cirino A, Mancini-DiNardo D, Clark E, Leon A, Duffy E, White E, Baxter S, Alaamery M, Farwell L, Weiss S, Seidman CE, Seidman JG, Ho CY, Rehm HL, Funke BH
published in: Genetics in medicine : official journal of the American College of Medical Genetics
information resource reference: A novel custom resequencing array for dilated cardiomyopathy. Genet Med. 2010 May; 12(5):268-78.
journal title abbreviation: Genet Med
publication date: 2010-05-01T00:00:00
year: 2010
type: Academic Article
type: Article
type: Document
type: Information Resource

Optimizing catecholaminergic polymorphic ventricular tachycardia therapy in calsequestrin-mutant mice.
PubMed Identifier: 20620233
author list: Katz G, Khoury A, Kurtzwald E, Hochhauser E, Porat E, Shainberg A, Seidman JG, Seidman CE, Lorber A, Eldar M, Arad M
published in: Heart rhythm
information resource reference: Optimizing catecholaminergic polymorphic ventricular tachycardia therapy in calsequestrin-mutant mice. Heart Rhythm. 2010 Nov; 7(11):1676-82.
journal title abbreviation: Heart Rhythm
publication date: 2010-07-08T00:00:00
year: 2010
type: Academic Article
type: Article
type: Document
type: Information Resource

Research priorities in hypertrophic cardiomyopathy: report of a Working Group of the National Heart, Lung, and Blood Institute.
PubMed Identifier: 20837938
author list: Force T, Bonow RO, Houser SR, Solaro RJ, Hershberger RE, Adhikari B, Anderson ME, Boineau R, Byrne BJ, Cappola TP, Kalluri R, LeWinter MM, Maron MS, Molkentin JD, Ommen SR, Regnier M, Tang WH, Tian R, Konstam MA, Maron BJ, Seidman CE
published in: Circulation
information resource reference: Research priorities in hypertrophic cardiomyopathy: report of a Working Group of the National Heart, Lung, and Blood Institute. Circulation. 2010 Sep 14; 122(11):1130-3.
journal title abbreviation: Circulation
publication date: 2010-09-14T00:00:00
year: 2010
type: Academic Article
type: Article
type: Document
type: Information Resource

Brazilian urban population genetic structure reveals a high degree of admixture.
PubMed Identifier: 21863058
author list: Giolo SR, Soler JM, Greenway SC, Almeida MA, de Andrade M, Seidman JG, Seidman CE, Krieger JE, Pereira AC
published in: European journal of human genetics : EJHG
information resource reference: Brazilian urban population genetic structure reveals a high degree of admixture. Eur J Hum Genet. 2012 Jan; 20(1):111-6.
journal title abbreviation: Eur J Hum Genet
publication date: 2011-08-24T00:00:00
year: 2011
type: Academic Article
type: Article
type: Document
type: Information Resource

Localized expression of the atrial natriuretic factor gene during cardiac embryogenesis.
PubMed Identifier: 2962900
author list: Zeller R, Bloch KD, Williams BS, Arceci RJ, Seidman CE
published in: Genes & development
information resource reference: Localized expression of the atrial natriuretic factor gene during cardiac embryogenesis. Genes Dev. 1987 Sep; 1(7):693-8.
journal title abbreviation: Genes Dev
publication date: 1987-09-01T00:00:00
year: 1987
type: Academic Article
type: Article
type: Document
type: Information Resource

Exercise training improves cardiac function and attenuates arrhythmia in CPVT mice.
PubMed Identifier: 23042908
author list: Kurtzwald-Josefson E, Hochhauser E, Katz G, Porat E, Seidman JG, Seidman CE, Chepurko Y, Shainberg A, Eldar M, Arad M
published in: Journal of applied physiology (Bethesda, Md. : 1985)
information resource reference: Exercise training improves cardiac function and attenuates arrhythmia in CPVT mice. J Appl Physiol (1985). 2012 Dec 01; 113(11):1677-83.
journal title abbreviation: J Appl Physiol (1985)
publication date: 2012-10-04T00:00:00
year: 2012
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1006323
type: Authorship
author rank in publication: 18
linked author: Seidman, Christine
linked information resource: Fabry Disease in Families With Hypertrophic Cardiomyopathy: Clinical Manifestations in the Classic and Later-Onset Phenotypes.

Fabry Disease in Families With Hypertrophic Cardiomyopathy: Clinical Manifestations in the Classic and Later-Onset Phenotypes.
PubMed Identifier: 28798024
author list: Adalsteinsdottir B, Palsson R, Desnick RJ, Gardarsdottir M, Teekakirikul P, Maron M, Appelbaum E, Neisius U, Maron BJ, Burke MA, Chen B, Pagant S, Madsen CV, Danielsen R, Arngrimsson R, Feldt-Rasmussen U, Seidman JG, Seidman CE, Gunnarsson GT
published in: Circulation. Cardiovascular genetics
information resource reference: Fabry Disease in Families With Hypertrophic Cardiomyopathy: Clinical Manifestations in the Classic and Later-Onset Phenotypes. Circ Cardiovasc Genet. 2017 Aug; 10(4).
journal title abbreviation: Circ Cardiovasc Genet
publication date: 2017-08-01T00:00:00
year: 2017
type: Academic Article
type: Article
type: Document
type: Information Resource

Genetic Determinants of Chagas Cardiomyopathy
end date: 2021-03-31
principal investigator name: SEIDMAN, CHRISTINE E
start date: 2017-04-01
type: Grant
sponsor award id: R01HL133165

Principal Investigator
type: Researcher Role
researcher role of: Seidman, Christine
contributes to: Genetic Determinants of Chagas Cardiomyopathy

Reduced penetrance, variable expressivity, and genetic heterogeneity of familial atrial septal defects.
PubMed Identifier: 9610535
author list: Benson DW, Sharkey A, Fatkin D, Lang P, Basson CT, McDonough B, Strauss AW, Seidman JG, Seidman CE
published in: Circulation
information resource reference: Reduced penetrance, variable expressivity, and genetic heterogeneity of familial atrial septal defects. Circulation. 1998 May 26; 97(20):2043-8.
journal title abbreviation: Circulation
publication date: 1998-05-26T00:00:00
year: 1998
type: Academic Article
type: Article
type: Document
type: Information Resource

Congenital heart disease caused by mutations in the transcription factor NKX2-5.
PubMed Identifier: 9651244
author list: Schott JJ, Benson DW, Basson CT, Pease W, Silberbach GM, Moak JP, Maron BJ, Seidman CE, Seidman JG
published in: Science (New York, N.Y.)
information resource reference: Congenital heart disease caused by mutations in the transcription factor NKX2-5. Science. 1998 Jul 03; 281(5373):108-11.
journal title abbreviation: Science
publication date: 1998-07-03T00:00:00
year: 1998
type: Academic Article
type: Article
type: Document
type: Information Resource

Dilated cardiomyopathy and sensorineural hearing loss: a heritable syndrome that maps to 6q23-24.
PubMed Identifier: 10769282
author list: Schönberger J, Levy H, Grünig E, Sangwatanaroj S, Fatkin D, MacRae C, Stäcker H, Halpin C, Eavey R, Philbin EF, Katus H, Seidman JG, Seidman CE
published in: Circulation
information resource reference: Dilated cardiomyopathy and sensorineural hearing loss: a heritable syndrome that maps to 6q23-24. Circulation. 2000 Apr 18; 101(15):1812-8.
journal title abbreviation: Circulation
publication date: 2000-04-18T00:00:00
year: 2000
type: Academic Article
type: Article
type: Document
type: Information Resource

The genetic basis for cardiomyopathy: from mutation identification to mechanistic paradigms.
PubMed Identifier: 11239412
author list: Seidman JG, Seidman C
published in: Cell
information resource reference: The genetic basis for cardiomyopathy: from mutation identification to mechanistic paradigms. Cell. 2001 Feb 23; 104(4):557-67.
journal title abbreviation: Cell
publication date: 2001-02-23T00:00:00
year: 2001
type: Academic Article
type: Article
type: Document
type: Information Resource

In memorium.
PubMed Identifier: 11448127
author list: Clapham D, Michel T, Seidman C
published in: Journal of molecular and cellular cardiology
information resource reference: In memorium. J Mol Cell Cardiol. 2001 Aug; 33(8):1393-4.
journal title abbreviation: J Mol Cell Cardiol
publication date: 2001-08-01T00:00:00
year: 2001
type: Academic Article
type: Article
type: Document
type: Information Resource

A murine model of Holt-Oram syndrome defines roles of the T-box transcription factor Tbx5 in cardiogenesis and disease.
PubMed Identifier: 11572777
author list: Bruneau BG, Nemer G, Schmitt JP, Charron F, Robitaille L, Caron S, Conner DA, Gessler M, Nemer M, Seidman CE, Seidman JG
published in: Cell
information resource reference: A murine model of Holt-Oram syndrome defines roles of the T-box transcription factor Tbx5 in cardiogenesis and disease. Cell. 2001 Sep 21; 106(6):709-21.
journal title abbreviation: Cell
publication date: 2001-09-21T00:00:00
year: 2001
type: Academic Article
type: Article
type: Document
type: Information Resource

Constitutively active AMP kinase mutations cause glycogen storage disease mimicking hypertrophic cardiomyopathy.
PubMed Identifier: 11827995
author list: Arad M, Benson DW, Perez-Atayde AR, McKenna WJ, Sparks EA, Kanter RJ, McGarry K, Seidman JG, Seidman CE
published in: The Journal of clinical investigation
information resource reference: Constitutively active AMP kinase mutations cause glycogen storage disease mimicking hypertrophic cardiomyopathy. J Clin Invest. 2002 Feb; 109(3):357-62.
journal title abbreviation: J Clin Invest
publication date: 2002-02-01T00:00:00
year: 2002
type: Academic Article
type: Article
type: Document
type: Information Resource

Assessment of diastolic function with Doppler tissue imaging to predict genotype in preclinical hypertrophic cardiomyopathy.
PubMed Identifier: 12081993
author list: Ho CY, Sweitzer NK, McDonough B, Maron BJ, Casey SA, Seidman JG, Seidman CE, Solomon SD
published in: Circulation
information resource reference: Assessment of diastolic function with Doppler tissue imaging to predict genotype in preclinical hypertrophic cardiomyopathy. Circulation. 2002 Jun 25; 105(25):2992-7.
journal title abbreviation: Circulation
publication date: 2002-06-25T00:00:00
year: 2002
type: Academic Article
type: Article
type: Document
type: Information Resource

Genetic causes of inherited cardiac hypertrophy: Robert L. Frye Lecture.
PubMed Identifier: 12479519
author list: Seidman C
published in: Mayo Clinic proceedings
information resource reference: Genetic causes of inherited cardiac hypertrophy: Robert L. Frye Lecture. Mayo Clin Proc. 2002 Dec; 77(12):1315-9.
journal title abbreviation: Mayo Clin Proc
publication date: 2002-12-01T00:00:00
year: 2002
type: Academic Article
type: Article
type: Document
type: Information Resource

Consequences of pressure overload on sarcomere protein mutation-induced hypertrophic cardiomyopathy.
PubMed Identifier: 12925456
author list: Schmitt JP, Semsarian C, Arad M, Gannon J, Ahmad F, Duffy C, Lee RT, Seidman CE, Seidman JG
published in: Circulation
information resource reference: Consequences of pressure overload on sarcomere protein mutation-induced hypertrophic cardiomyopathy. Circulation. 2003 Sep 02; 108(9):1133-8.
journal title abbreviation: Circulation
publication date: 2003-08-18T00:00:00
year: 2003
type: Academic Article
type: Article
type: Document
type: Information Resource

The genetic basis for cardiac remodeling.
PubMed Identifier: 16124859
author list: Ahmad F, Seidman JG, Seidman CE
published in: Annual review of genomics and human genetics
information resource reference: The genetic basis for cardiac remodeling. Annu Rev Genomics Hum Genet. 2005; 6:185-216.
journal title abbreviation: Annu Rev Genomics Hum Genet
publication date: 2005-01-01T00:00:00
year: 2005
type: Academic Article
type: Article
type: Document
type: Information Resource

Genetic basis of hypertrophic cardiomyopathy: from bench to the clinics.
PubMed Identifier: 17916152
author list: Alcalai R, Seidman JG, Seidman CE
published in: Journal of cardiovascular electrophysiology
information resource reference: Genetic basis of hypertrophic cardiomyopathy: from bench to the clinics. J Cardiovasc Electrophysiol. 2008 Jan; 19(1):104-10.
journal title abbreviation: J Cardiovasc Electrophysiol
publication date: 2007-10-04T00:00:00
year: 2007
type: Academic Article
type: Article
type: Document
type: Information Resource

Eya4-deficient mice are a model for heritable otitis media.
PubMed Identifier: 18219393
author list: Depreux FF, Darrow K, Conner DA, Eavey RD, Liberman MC, Seidman CE, Seidman JG
published in: The Journal of clinical investigation
information resource reference: Eya4-deficient mice are a model for heritable otitis media. J Clin Invest. 2008 Feb; 118(2):651-8.
journal title abbreviation: J Clin Invest
publication date: 2008-02-01T00:00:00
year: 2008
type: Academic Article
type: Article
type: Document
type: Information Resource

Introduction of plasmid DNA into cells.
PubMed Identifier: 18428443
author list: Seidman CE, Struhl K
published in: Current protocols in neuroscience
information resource reference: Introduction of plasmid DNA into cells. Curr Protoc Neurosci. 2001 May; Appendix 1:Appendix 1L.
journal title abbreviation: Curr Protoc Neurosci
publication date: 2001-05-01T00:00:00
year: 2001
type: Academic Article
type: Article
type: Document
type: Information Resource

Genetic evaluation of cardiomyopathy--a Heart Failure Society of America practice guideline.
PubMed Identifier: 19254666
author list: Hershberger RE, Lindenfeld J, Mestroni L, Seidman CE, Taylor MR, Towbin JA
published in: Journal of cardiac failure
information resource reference: Genetic evaluation of cardiomyopathy--a Heart Failure Society of America practice guideline. J Card Fail. 2009 Mar; 15(2):83-97.
journal title abbreviation: J Card Fail
publication date: 2009-03-01T00:00:00
year: 2009
type: Academic Article
type: Article
type: Document
type: Information Resource

Ca2+ dysregulation in Ryr1(I4895T/wt) mice causes congenital myopathy with progressive formation of minicores, cores, and nemaline rods.
PubMed Identifier: 19959667
author list: Zvaritch E, Kraeva N, Bombardier E, McCloy RA, Depreux F, Holmyard D, Kraev A, Seidman CE, Seidman JG, Tupling AR, MacLennan DH
published in: Proceedings of the National Academy of Sciences of the United States of America
information resource reference: Ca2+ dysregulation in Ryr1(I4895T/wt) mice causes congenital myopathy with progressive formation of minicores, cores, and nemaline rods. Proc Natl Acad Sci U S A. 2009 Dec 22; 106(51):21813-8.
journal title abbreviation: Proc Natl Acad Sci U S A
publication date: 2009-12-03T00:00:00
year: 2009
type: Academic Article
type: Article
type: Document
type: Information Resource

Genome-wide identification of mouse congenital heart disease loci.
PubMed Identifier: 20511334
author list: Kamp A, Peterson MA, Svenson KL, Bjork BC, Hentges KE, Rajapaksha TW, Moran J, Justice MJ, Seidman JG, Seidman CE, Moskowitz IP, Beier DR
published in: Human molecular genetics
information resource reference: Genome-wide identification of mouse congenital heart disease loci. Hum Mol Genet. 2010 Aug 15; 19(16):3105-13.
journal title abbreviation: Hum Mol Genet
publication date: 2010-05-28T00:00:00
year: 2010
type: Academic Article
type: Article
type: Document
type: Information Resource

Activation of multiple signaling pathways causes developmental defects in mice with a Noonan syndrome–associated Sos1 mutation.
PubMed Identifier: 21041952
author list: Chen PC, Wakimoto H, Conner D, Araki T, Yuan T, Roberts A, Seidman C, Bronson R, Neel B, Seidman JG, Kucherlapati R
published in: The Journal of clinical investigation
information resource reference: Activation of multiple signaling pathways causes developmental defects in mice with a Noonan syndrome–associated Sos1 mutation. J Clin Invest. 2010 Dec; 120(12):4353-65.
journal title abbreviation: J Clin Invest
publication date: 2010-12-01T00:00:00
year: 2010
type: Academic Article
type: Article
type: Document
type: Information Resource

https://connects.catalyst.harvard.edu/Profiles/profile/894755
PubMed Identifier: 9841131
author list: Maron BJ, Moller JH, Seidman CE, Vincent GM, Dietz HC, Moss AJ, Sondheimer HM, Pyeritz RE, McGee G, Epstein AE
published in: Circulation
information resource reference: Impact of laboratory molecular diagnosis on contemporary diagnostic criteria for genetically transmitted cardiovascular diseases:hypertrophic cardiomyopathy, long-QT syndrome, and Marfan syndrome. A statement for healthcare professionals from the Councils on Clinical Cardiology, Cardiovascular Disease in the Young, and Basic Science, American Heart Association. Circulation. 1998 Oct 06; 98(14):1460-71.
journal title abbreviation: Circulation
publication date: 1998-10-06T00:00:00
year: 1998
type: Academic Article
type: Article
type: Document
type: Information Resource
label: Impact of laboratory molecular diagnosis on contemporary diagnostic criteria for genetically transmitted cardiovascular diseases:hypertrophic cardiomyopathy, long-QT syndrome, and Marfan syndrome. A statement for healthcare professionals from the Councils on Clinical Cardiology, Cardiovascular Disease in the Young, and Basic Science, American Heart Association.

Synthesis and characterization of a radioiodinated photoaffinity probe for the alpha 1-adrenergic receptor.
PubMed Identifier: 6327524
author list: Seidman CE, Hess HJ, Homcy CJ, Graham RM
published in: Hypertension (Dallas, Tex. : 1979)
information resource reference: Synthesis and characterization of a radioiodinated photoaffinity probe for the alpha 1-adrenergic receptor. Hypertension. 1984 Mar-Apr; 6(2 Pt 2):I7-11.
journal title abbreviation: Hypertension
publication date: 1984-03-01T00:00:00
year: 1984
type: Academic Article
type: Article
type: Document
type: Information Resource

Isolation of a de novo mutant myocardial beta MHC protein in a pedigree with hypertrophic cardiomyopathy.
PubMed Identifier: 7874131
author list: Greve G, Bachinski L, Friedman DL, Czernuzewicz G, Anan R, Towbin J, Seidman CE, Roberts R
published in: Human molecular genetics
information resource reference: Isolation of a de novo mutant myocardial beta MHC protein in a pedigree with hypertrophic cardiomyopathy. Hum Mol Genet. 1994 Nov; 3(11):2073-5.
journal title abbreviation: Hum Mol Genet
publication date: 1994-11-01T00:00:00
year: 1994
type: Academic Article
type: Article
type: Document
type: Information Resource

https://connects.catalyst.harvard.edu/Profiles/profile/904411
PubMed Identifier: 14607462
author list: Maron BJ, McKenna WJ, Danielson GK, Kappenberger LJ, Kuhn HJ, Seidman CE, Shah PM, Spencer WH, Spirito P, Ten Cate FJ, Wigle ED
published in: Journal of the American College of Cardiology
information resource reference: American College of Cardiology/European Society of Cardiology clinical expert consensus document on hypertrophic cardiomyopathy. A report of the American College of Cardiology Foundation Task Force on Clinical Expert Consensus Documents and the European Society of Cardiology Committee for Practice Guidelines. J Am Coll Cardiol. 2003 Nov 05; 42(9):1687-713.
journal title abbreviation: J Am Coll Cardiol
publication date: 2003-11-05T00:00:00
year: 2003
type: Academic Article
type: Article
type: Document
type: Information Resource
label: American College of Cardiology/European Society of Cardiology clinical expert consensus document on hypertrophic cardiomyopathy. A report of the American College of Cardiology Foundation Task Force on Clinical Expert Consensus Documents and the European Society of Cardiology Committee for Practice Guidelines.

Clinical and genetic linkage analysis of a large Venezuelan kindred with Usher syndrome.
PubMed Identifier: 15236894
author list: Keogh IJ, Godinho RN, Wu TP, Diaz de Palacios AM, Palacios N, Bello de Alford M, De Almada MI, MarPalacios N, Vazquez A, Mattei R, Seidman C, Seidman J, Eavey RD
published in: International journal of pediatric otorhinolaryngology
information resource reference: Clinical and genetic linkage analysis of a large Venezuelan kindred with Usher syndrome. Int J Pediatr Otorhinolaryngol. 2004 Aug; 68(8):1063-8.
journal title abbreviation: Int J Pediatr Otorhinolaryngol
publication date: 2004-08-01T00:00:00
year: 2004
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1017918
type: Authorship
author rank in publication: 43
linked author: Seidman, Christine
linked information resource: Contribution of rare inherited and de novo variants in 2,871 congenital heart disease probands.

Authorship 1019323
type: Authorship
author rank in publication: 2
linked author: Seidman, Christine
linked information resource: Closing the Genotype-Phenotype Loop for Precision Medicine.

Authorship 1019256
type: Authorship
author rank in publication: 14
linked author: Seidman, Christine
linked information resource: A Comparison of Whole Genome Sequencing to Multigene Panel Testing in Hypertrophic Cardiomyopathy Patients.

A Comparison of Whole Genome Sequencing to Multigene Panel Testing in Hypertrophic Cardiomyopathy Patients.
PubMed Identifier: 29030401
author list: Cirino AL, Lakdawala NK, McDonough B, Conner L, Adler D, Weinfeld M, O'Gara P, Rehm HL, Machini K, Lebo M, Blout C, Green RC, MacRae CA, Seidman CE, Ho CY
published in: Circulation. Cardiovascular genetics
information resource reference: A Comparison of Whole Genome Sequencing to Multigene Panel Testing in Hypertrophic Cardiomyopathy Patients. Circ Cardiovasc Genet. 2017 Oct; 10(5).
journal title abbreviation: Circ Cardiovasc Genet
publication date: 2017-10-01T00:00:00
year: 2017
type: Academic Article
type: Article
type: Document
type: Information Resource

Contribution of rare inherited and de novo variants in 2,871 congenital heart disease probands.
PubMed Identifier: 28991257
author list: Jin SC, Homsy J, Zaidi S, Lu Q, Morton S, DePalma SR, Zeng X, Qi H, Chang W, Sierant MC, Hung WC, Haider S, Zhang J, Knight J, Bjornson RD, Castaldi C, Tikhonoa IR, Bilguvar K, Mane SM, Sanders SJ, Mital S, Russell MW, Gaynor JW, Deanfield J, Giardini A, Porter GA, Srivastava D, Lo CW, Shen Y, Watkins WS, Yandell M, Yost HJ, Tristani-Firouzi M, Newburger JW, Roberts AE, Kim R, Zhao H, Kaltman JR, Goldmuntz E, Chung WK, Seidman JG, Gelb BD, Seidman CE, Lifton RP, Brueckner M
published in: Nature genetics
information resource reference: Contribution of rare inherited and de novo variants in 2,871 congenital heart disease probands. Nat Genet. 2017 Nov; 49(11):1593-1601.
journal title abbreviation: Nat Genet
publication date: 2017-10-09T00:00:00
year: 2017
type: Academic Article
type: Article
type: Document
type: Information Resource

Closing the Genotype-Phenotype Loop for Precision Medicine.
PubMed Identifier: 29038206
author list: MacRae CA, Seidman CE
published in: Circulation
information resource reference: Closing the Genotype-Phenotype Loop for Precision Medicine. Circulation. 2017 10 17; 136(16):1492-1494.
journal title abbreviation: Circulation
publication date: 2017-10-17T00:00:00
year: 2017
type: Academic Article
type: Article
type: Document
type: Information Resource

Preclinical diagnosis of familial hypertrophic cardiomyopathy by genetic analysis of blood lymphocytes.
PubMed Identifier: 1944483
author list: Rosenzweig A, Watkins H, Hwang DS, Miri M, McKenna W, Traill TA, Seidman JG, Seidman CE
published in: The New England journal of medicine
information resource reference: Preclinical diagnosis of familial hypertrophic cardiomyopathy by genetic analysis of blood lymphocytes. N Engl J Med. 1991 Dec 19; 325(25):1753-60.
journal title abbreviation: N Engl J Med
publication date: 1991-12-19T00:00:00
year: 1991
type: Academic Article
type: Article
type: Document
type: Information Resource

A contemporary approach to hypertrophic cardiomyopathy.
PubMed Identifier: 16785342
author list: Ho CY, Seidman CE
published in: Circulation
information resource reference: A contemporary approach to hypertrophic cardiomyopathy. Circulation. 2006 Jun 20; 113(24):e858-62.
journal title abbreviation: Circulation
publication date: 2006-06-20T00:00:00
year: 2006
type: Academic Article
type: Article
type: Document
type: Information Resource

Tbx5-dependent rheostatic control of cardiac gene expression and morphogenesis.
PubMed Identifier: 16870172
author list: Mori AD, Zhu Y, Vahora I, Nieman B, Koshiba-Takeuchi K, Davidson L, Pizard A, Seidman JG, Seidman CE, Chen XJ, Henkelman RM, Bruneau BG
published in: Developmental biology
information resource reference: Tbx5-dependent rheostatic control of cardiac gene expression and morphogenesis. Dev Biol. 2006 Sep 15; 297(2):566-86.
journal title abbreviation: Dev Biol
publication date: 2006-05-24T00:00:00
year: 2006
type: Academic Article
type: Article
type: Document
type: Information Resource

Eya4 regulation of Na+/K+-ATPase is required for sensory system development in zebrafish.
PubMed Identifier: 18799547
author list: Wang L, Sewell WF, Kim SD, Shin JT, MacRae CA, Zon LI, Seidman JG, Seidman CE
published in: Development (Cambridge, England)
information resource reference: Eya4 regulation of Na+/K+-ATPase is required for sensory system development in zebrafish. Development. 2008 Oct; 135(20):3425-34.
journal title abbreviation: Development
publication date: 2008-09-17T00:00:00
year: 2008
type: Academic Article
type: Article
type: Document
type: Information Resource

How should hypertrophic cardiomyopathy be classified?: What's in a name? Dilemmas in nomenclature characterizing hypertrophic cardiomyopathy and left ventricular hypertrophy.
PubMed Identifier: 20031569
author list: Maron BJ, Seidman CE, Ackerman MJ, Towbin JA, Maron MS, Ommen SR, Nishimura RA, Gersh BJ
published in: Circulation. Cardiovascular genetics
information resource reference: How should hypertrophic cardiomyopathy be classified?: What's in a name? Dilemmas in nomenclature characterizing hypertrophic cardiomyopathy and left ventricular hypertrophy. Circ Cardiovasc Genet. 2009 Feb; 2(1):81-5; discussion 86.
journal title abbreviation: Circ Cardiovasc Genet
publication date: 2009-02-01T00:00:00
year: 2009
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1021524
type: Authorship
author rank in publication: 11
linked author: Seidman, Christine
linked information resource: Cardiovascular homeostasis dependence on MICU2, a regulatory subunit of the mitochondrial calcium uniporter.

Cardiovascular homeostasis dependence on MICU2, a regulatory subunit of the mitochondrial calcium uniporter.
PubMed Identifier: 29073106
author list: Bick AG, Wakimoto H, Kamer KJ, Sancak Y, Goldberger O, Axelsson A, DeLaughter DM, Gorham JM, Mootha VK, Seidman JG, Seidman CE
published in: Proceedings of the National Academy of Sciences of the United States of America
information resource reference: Cardiovascular homeostasis dependence on MICU2, a regulatory subunit of the mitochondrial calcium uniporter. Proc Natl Acad Sci U S A. 2017 10 24; 114(43):E9096-E9104.
journal title abbreviation: Proc Natl Acad Sci U S A
publication date: 2017-10-09T00:00:00
year: 2017
type: Academic Article
type: Article
type: Document
type: Information Resource

Comparative proteomics profiling of a phospholamban mutant mouse model of dilated cardiomyopathy reveals progressive intracellular stress responses.
PubMed Identifier: 18056057
author list: Gramolini AO, Kislinger T, Alikhani-Koopaei R, Fong V, Thompson NJ, Isserlin R, Sharma P, Oudit GY, Trivieri MG, Fagan A, Kannan A, Higgins DG, Huedig H, Hess G, Arab S, Seidman JG, Seidman CE, Frey B, Perry M, Backx PH, Liu PP, MacLennan DH, Emili A
published in: Molecular & cellular proteomics : MCP
information resource reference: Comparative proteomics profiling of a phospholamban mutant mouse model of dilated cardiomyopathy reveals progressive intracellular stress responses. Mol Cell Proteomics. 2008 Mar; 7(3):519-33.
journal title abbreviation: Mol Cell Proteomics
publication date: 2007-11-30T00:00:00
year: 2007
type: Academic Article
type: Article
type: Document
type: Information Resource

Molecular approaches to the study of atrial natriuretic factor.
PubMed Identifier: 2959153
author list: Seidman CE, Bloch KD
published in: The American journal of the medical sciences
information resource reference: Molecular approaches to the study of atrial natriuretic factor. Am J Med Sci. 1987 Sep; 294(3):144-9.
journal title abbreviation: Am J Med Sci
publication date: 1987-09-01T00:00:00
year: 1987
type: Academic Article
type: Article
type: Document
type: Information Resource

Cis-acting sequences that modulate atrial natriuretic factor gene expression.
PubMed Identifier: 2967498
author list: Seidman CE, Wong DW, Jarcho JA, Bloch KD, Seidman JG
published in: Proceedings of the National Academy of Sciences of the United States of America
information resource reference: Cis-acting sequences that modulate atrial natriuretic factor gene expression. Proc Natl Acad Sci U S A. 1988 Jun; 85(11):4104-8.
journal title abbreviation: Proc Natl Acad Sci U S A
publication date: 1988-06-01T00:00:00
year: 1988
type: Academic Article
type: Article
type: Document
type: Information Resource

The PTPN11 gene is not implicated in nonsyndromic hypertrophic cardiomyopathy.
PubMed Identifier: 15578621
author list: Roberts AE, Hult B, Rehm HL, Rehm HL, McDonough B, Barr S, Seidman CE, Seidman JG, Kucherlapati RS
published in: American journal of medical genetics. Part A
information resource reference: The PTPN11 gene is not implicated in nonsyndromic hypertrophic cardiomyopathy. Am J Med Genet A. 2005 Jan 30; 132A(3):333-4.
journal title abbreviation: Am J Med Genet A
publication date: 2005-01-30T00:00:00
year: 2005
type: Academic Article
type: Article
type: Document
type: Information Resource

Mutations in the cardiac transcription factor NKX2.5 affect diverse cardiac developmental pathways.
PubMed Identifier: 10587520
author list: Benson DW, Silberbach GM, Kavanaugh-McHugh A, Cottrill C, Zhang Y, Riggs S, Smalls O, Johnson MC, Watson MS, Seidman JG, Seidman CE, Plowden J, Kugler JD
published in: The Journal of clinical investigation
information resource reference: Mutations in the cardiac transcription factor NKX2.5 affect diverse cardiac developmental pathways. J Clin Invest. 1999 Dec; 104(11):1567-73.
journal title abbreviation: J Clin Invest
publication date: 1999-12-01T00:00:00
year: 1999
type: Academic Article
type: Article
type: Document
type: Information Resource

AMP-activated protein kinase in the heart: role during health and disease.
PubMed Identifier: 17332438
author list: Arad M, Seidman CE, Seidman JG
published in: Circulation research
information resource reference: AMP-activated protein kinase in the heart: role during health and disease. Circ Res. 2007 Mar 02; 100(4):474-88.
journal title abbreviation: Circ Res
publication date: 2007-03-02T00:00:00
year: 2007
type: Academic Article
type: Article
type: Document
type: Information Resource

Loss of function and inhibitory effects of human CSX/NKX2.5 homeoprotein mutations associated with congenital heart disease.
PubMed Identifier: 10903346
author list: Kasahara H, Lee B, Schott JJ, Benson DW, Seidman JG, Seidman CE, Izumo S
published in: The Journal of clinical investigation
information resource reference: Loss of function and inhibitory effects of human CSX/NKX2.5 homeoprotein mutations associated with congenital heart disease. J Clin Invest. 2000 Jul; 106(2):299-308.
journal title abbreviation: J Clin Invest
publication date: 2000-07-01T00:00:00
year: 2000
type: Academic Article
type: Article
type: Document
type: Information Resource

Cloning, expression, and chromosomal location of SHH and IHH: two human homologues of the Drosophila segment polarity gene hedgehog.
PubMed Identifier: 7590746
author list: Marigo V, Roberts DJ, Lee SM, Tsukurov O, Levi T, Gastier JM, Epstein DJ, Gilbert DJ, Copeland NG, Seidman CE
published in: Genomics
information resource reference: Cloning, expression, and chromosomal location of SHH and IHH: two human homologues of the Drosophila segment polarity gene hedgehog. Genomics. 1995 Jul 01; 28(1):44-51.
journal title abbreviation: Genomics
publication date: 1995-07-01T00:00:00
year: 1995
type: Academic Article
type: Article
type: Document
type: Information Resource

Variation in the 4q25 chromosomal locus predicts atrial fibrillation after coronary artery bypass graft surgery.
PubMed Identifier: 20031626
author list: Body SC, Collard CD, Shernan SK, Fox AA, Liu KY, Ritchie MD, Perry TE, Muehlschlegel JD, Aranki S, Donahue BS, Pretorius M, Estrada JC, Ellinor PT, Newton-Cheh C, Seidman CE, Seidman JG, Herman DS, Lichtner P, Meitinger T, Pfeufer A, Kääb S, Brown NJ, Roden DM, Darbar D
published in: Circulation. Cardiovascular genetics
information resource reference: Variation in the 4q25 chromosomal locus predicts atrial fibrillation after coronary artery bypass graft surgery. Circ Cardiovasc Genet. 2009 Oct; 2(5):499-506.
journal title abbreviation: Circ Cardiovasc Genet
publication date: 2009-08-02T00:00:00
year: 2009
type: Academic Article
type: Article
type: Document
type: Information Resource

IL-12 is required for differentiation of pathogenic CD8+ T cell effectors that cause myocarditis.
PubMed Identifier: 12618521
author list: Grabie N, Delfs MW, Westrich JR, Love VA, Stavrakis G, Ahmad F, Seidman CE, Seidman JG, Lichtman AH
published in: The Journal of clinical investigation
information resource reference: IL-12 is required for differentiation of pathogenic CD8+ T cell effectors that cause myocarditis. J Clin Invest. 2003 Mar; 111(5):671-80.
journal title abbreviation: J Clin Invest
publication date: 2003-03-01T00:00:00
year: 2003
type: Academic Article
type: Article
type: Document
type: Information Resource

The T-Box transcription factor Tbx5 is required for the patterning and maturation of the murine cardiac conduction system.
PubMed Identifier: 15289437
author list: Moskowitz IP, Pizard A, Patel VV, Bruneau BG, Kim JB, Kupershmidt S, Roden D, Berul CI, Seidman CE, Seidman JG
published in: Development (Cambridge, England)
information resource reference: The T-Box transcription factor Tbx5 is required for the patterning and maturation of the murine cardiac conduction system. Development. 2004 Aug; 131(16):4107-16.
journal title abbreviation: Development
publication date: 2004-08-01T00:00:00
year: 2004
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1028754
type: Authorship
author rank in publication: 45
linked author: Seidman, Christine
linked information resource: IL-11 is a crucial determinant of cardiovascular fibrosis.

IL-11 is a crucial determinant of cardiovascular fibrosis.
PubMed Identifier: 29160304
author list: Schafer S, Viswanathan S, Widjaja AA, Lim WW, Moreno-Moral A, DeLaughter DM, Ng B, Patone G, Chow K, Khin E, Tan J, Chothani SP, Ye L, Rackham OJL, Ko NSJ, Sahib NE, Pua CJ, Zhen NTG, Xie C, Wang M, Maatz H, Lim S, Saar K, Blachut S, Petretto E, Schmidt S, Putoczki T, Guimarães-Camboa N, Wakimoto H, van Heesch S, Sigmundsson K, Lim SL, Soon JL, Chao VTT, Chua YL, Tan TE, Evans SM, Loh YJ, Jamal MH, Ong KK, Chua KC, Ong BH, Chakaramakkil MJ, Seidman JG, Seidman CE, Hubner N, Sin KYK, Cook SA
published in: Nature
information resource reference: IL-11 is a crucial determinant of cardiovascular fibrosis. Nature. 2017 12 07; 552(7683):110-115.
journal title abbreviation: Nature
publication date: 2017-11-13T00:00:00
year: 2017
type: Academic Article
type: Article
type: Document
type: Information Resource

Heterozygosity for a loss-of-function mutation in GALNT2 improves plasma triglyceride clearance in man.
PubMed Identifier: 22152306
author list: Holleboom AG, Karlsson H, Lin RS, Beres TM, Sierts JA, Herman DS, Stroes ES, Aerts JM, Kastelein JJ, Motazacker MM, Dallinga-Thie GM, Levels JH, Zwinderman AH, Seidman JG, Seidman CE, Ljunggren S, Lefeber DJ, Morava E, Wevers RA, Fritz TA, Tabak LA, Lindahl M, Hovingh GK, Kuivenhoven JA
published in: Cell metabolism
information resource reference: Heterozygosity for a loss-of-function mutation in GALNT2 improves plasma triglyceride clearance in man. Cell Metab. 2011 Dec 07; 14(6):811-8.
journal title abbreviation: Cell Metab
publication date: 2011-12-07T00:00:00
year: 2011
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1030073
type: Authorship
author rank in publication: 7
linked author: Seidman, Christine
linked information resource: Cardiac-enriched BAF chromatin-remodeling complex subunit Baf60c regulates gene expression programs essential for heart development and function.

Cardiac-enriched BAF chromatin-remodeling complex subunit Baf60c regulates gene expression programs essential for heart development and function.
PubMed Identifier: 29183906
author list: Sun X, Hota SK, Zhou YQ, Novak S, Miguel-Perez D, Christodoulou D, Seidman CE, Seidman JG, Gregorio CC, Henkelman RM, Rossant J, Bruneau BG
published in: Biology open
information resource reference: Cardiac-enriched BAF chromatin-remodeling complex subunit Baf60c regulates gene expression programs essential for heart development and function. Biol Open. 2018 Jan 05; 7(1).
journal title abbreviation: Biol Open
publication date: 2018-01-05T00:00:00
year: 2018
type: Academic Article
type: Article
type: Document
type: Information Resource

Polycomb repressive complex 2 regulates normal development of the mouse heart.
PubMed Identifier: 22158708
author list: He A, Ma Q, Cao J, von Gise A, Zhou P, Xie H, Zhang B, Hsing M, Christodoulou DC, Cahan P, Daley GQ, Kong SW, Orkin SH, Seidman CE, Seidman JG, Pu WT
published in: Circulation research
information resource reference: Polycomb repressive complex 2 regulates normal development of the mouse heart. Circ Res. 2012 Feb 03; 110(3):406-15.
journal title abbreviation: Circ Res
publication date: 2011-12-08T00:00:00
year: 2011
type: Academic Article
type: Article
type: Document
type: Information Resource

Deletion of thioredoxin-interacting protein in mice impairs mitochondrial function but protects the myocardium from ischemia-reperfusion injury.
PubMed Identifier: 22201682
author list: Yoshioka J, Chutkow WA, Lee S, Kim JB, Yan J, Tian R, Lindsey ML, Feener EP, Seidman CE, Seidman JG, Lee RT
published in: The Journal of clinical investigation
information resource reference: Deletion of thioredoxin-interacting protein in mice impairs mitochondrial function but protects the myocardium from ischemia-reperfusion injury. J Clin Invest. 2012 Jan; 122(1):267-79.
journal title abbreviation: J Clin Invest
publication date: 2011-12-27T00:00:00
year: 2011
type: Academic Article
type: Article
type: Document
type: Information Resource

Truncations of titin causing dilated cardiomyopathy.
PubMed Identifier: 22335739
author list: Herman DS, Lam L, Taylor MR, Wang L, Teekakirikul P, Christodoulou D, Conner L, DePalma SR, McDonough B, Sparks E, Teodorescu DL, Cirino AL, Banner NR, Pennell DJ, Graw S, Merlo M, Di Lenarda A, Sinagra G, Bos JM, Ackerman MJ, Mitchell RN, Murry CE, Lakdawala NK, Ho CY, Barton PJ, Cook SA, Mestroni L, Seidman JG, Seidman CE
published in: The New England journal of medicine
information resource reference: Truncations of titin causing dilated cardiomyopathy. N Engl J Med. 2012 Feb 16; 366(7):619-28.
journal title abbreviation: N Engl J Med
publication date: 2012-02-16T00:00:00
year: 2012
type: Academic Article
type: Article
type: Document
type: Information Resource

Calcium-ion-sensing cell-surface receptors.
PubMed Identifier: 7791841
author list: Brown EM, Pollak M, Seidman CE, Seidman JG, Chou YH, Riccardi D, Hebert SC
published in: The New England journal of medicine
information resource reference: Calcium-ion-sensing cell-surface receptors. N Engl J Med. 1995 Jul 27; 333(4):234-40.
journal title abbreviation: N Engl J Med
publication date: 1995-07-27T00:00:00
year: 1995
type: Academic Article
type: Article
type: Document
type: Information Resource

A mouse model of familial hypertrophic cardiomyopathy.
PubMed Identifier: 8614836
author list: Geisterfer-Lowrance AA, Christe M, Conner DA, Ingwall JS, Schoen FJ, Seidman CE, Seidman JG
published in: Science (New York, N.Y.)
information resource reference: A mouse model of familial hypertrophic cardiomyopathy. Science. 1996 May 03; 272(5262):731-4.
journal title abbreviation: Science
publication date: 1996-05-03T00:00:00
year: 1996
type: Academic Article
type: Article
type: Document
type: Information Resource

Atrial natriuretic factor gene expression in ventricles of rats with spontaneous biventricular hypertrophy.
PubMed Identifier: 2963021
author list: Lee RT, Bloch KD, Pfeffer JM, Pfeffer MA, Neer EJ, Seidman CE
published in: The Journal of clinical investigation
information resource reference: Atrial natriuretic factor gene expression in ventricles of rats with spontaneous biventricular hypertrophy. J Clin Invest. 1988 Feb; 81(2):431-4.
journal title abbreviation: J Clin Invest
publication date: 1988-02-01T00:00:00
year: 1988
type: Academic Article
type: Article
type: Document
type: Information Resource

Ouabain induces secretion of proatrial natriuretic factor by rat atrial cardiocytes.
PubMed Identifier: 2971323
author list: Bloch KD, Zamir N, Lichtstein D, Seidman CE, Seidman JG
published in: The American journal of physiology
information resource reference: Ouabain induces secretion of proatrial natriuretic factor by rat atrial cardiocytes. Am J Physiol. 1988 Sep; 255(3 Pt 1):E383-7.
journal title abbreviation: Am J Physiol
publication date: 1988-09-01T00:00:00
year: 1988
type: Academic Article
type: Article
type: Document
type: Information Resource

Genetic and environmental risk factors in congenital heart disease functionally converge in protein networks driving heart development.
PubMed Identifier: 22904188
author list: Lage K, Greenway SC, Rosenfeld JA, Wakimoto H, Gorham JM, Segrè AV, Roberts AE, Smoot LB, Pu WT, Pereira AC, Mesquita SM, Tommerup N, Brunak S, Ballif BC, Shaffer LG, Donahoe PK, Daly MJ, Seidman JG, Seidman CE, Larsen LA
published in: Proceedings of the National Academy of Sciences of the United States of America
information resource reference: Genetic and environmental risk factors in congenital heart disease functionally converge in protein networks driving heart development. Proc Natl Acad Sci U S A. 2012 Aug 28; 109(35):14035-40.
journal title abbreviation: Proc Natl Acad Sci U S A
publication date: 2012-08-16T00:00:00
year: 2012
type: Academic Article
type: Article
type: Document
type: Information Resource

Alterations of phospholamban function can exhibit cardiotoxic effects independent of excessive sarcoplasmic reticulum Ca2+-ATPase inhibition.
PubMed Identifier: 19139388
author list: Schmitt JP, Ahmad F, Lorenz K, Hein L, Schulz S, Asahi M, Maclennan DH, Seidman CE, Seidman JG, Lohse MJ
published in: Circulation
information resource reference: Alterations of phospholamban function can exhibit cardiotoxic effects independent of excessive sarcoplasmic reticulum Ca2+-ATPase inhibition. Circulation. 2009 Jan 27; 119(3):436-44.
journal title abbreviation: Circulation
publication date: 2009-01-12T00:00:00
year: 2009
type: Academic Article
type: Article
type: Document
type: Information Resource

Clinical outcome and phenotypic expression in LAMP2 cardiomyopathy.
PubMed Identifier: 19318653
author list: Maron BJ, Roberts WC, Arad M, Haas TS, Spirito P, Wright GB, Almquist AK, Baffa JM, Saul JP, Ho CY, Seidman J, Seidman CE
published in: JAMA
information resource reference: Clinical outcome and phenotypic expression in LAMP2 cardiomyopathy. JAMA. 2009 Mar 25; 301(12):1253-9.
journal title abbreviation: JAMA
publication date: 2009-03-25T00:00:00
year: 2009
type: Academic Article
type: Article
type: Document
type: Information Resource

Natriuretic peptide system gene variants are associated with ventricular dysfunction after coronary artery bypass grafting.
PubMed Identifier: 19326473
author list: Fox AA, Collard CD, Shernan SK, Seidman CE, Seidman JG, Liu KY, Muehlschlegel JD, Perry TE, Aranki SF, Lange C, Herman DS, Meitinger T, Lichtner P, Body SC
published in: Anesthesiology
information resource reference: Natriuretic peptide system gene variants are associated with ventricular dysfunction after coronary artery bypass grafting. Anesthesiology. 2009 Apr; 110(4):738-47.
journal title abbreviation: Anesthesiology
publication date: 2009-04-01T00:00:00
year: 2009
type: Academic Article
type: Article
type: Document
type: Information Resource

De novo copy number variants identify new genes and loci in isolated sporadic tetralogy of Fallot.
PubMed Identifier: 19597493
author list: Greenway SC, Pereira AC, Lin JC, DePalma SR, Israel SJ, Mesquita SM, Ergul E, Conta JH, Korn JM, McCarroll SA, Gorham JM, Gabriel S, Altshuler DM, Quintanilla-Dieck Mde L, Artunduaga MA, Eavey RD, Plenge RM, Shadick NA, Weinblatt ME, De Jager PL, Hafler DA, Breitbart RE, Seidman JG, Seidman CE
published in: Nature genetics
information resource reference: De novo copy number variants identify new genes and loci in isolated sporadic tetralogy of Fallot. Nat Genet. 2009 Aug; 41(8):931-5.
journal title abbreviation: Nat Genet
publication date: 2009-07-13T00:00:00
year: 2009
type: Academic Article
type: Article
type: Document
type: Information Resource

Heritable cardiac conduction and myocardial disease: from the clinic to the basic science laboratory and back to the clinic.
PubMed Identifier: 21691096
author list: Sparks EA, Boudoulas KD, Raman SV, Sasaki T, Graber HL, Nelson SD, Seidman CE, Boudoulas H
published in: Cardiology
information resource reference: Heritable cardiac conduction and myocardial disease: from the clinic to the basic science laboratory and back to the clinic. Cardiology. 2011; 118(3):179-86.
journal title abbreviation: Cardiology
publication date: 2011-06-17T00:00:00
year: 2011
type: Academic Article
type: Article
type: Document
type: Information Resource

https://connects.catalyst.harvard.edu/Profiles/profile/952589
PubMed Identifier: 22075468
author list: Gersh BJ, Maron BJ, Bonow RO, Dearani JA, Fifer MA, Link MS, Naidu SS, Nishimura RA, Ommen SR, Rakowski H, Seidman CE, Towbin JA, Udelson JE, Yancy CW
published in: Journal of the American College of Cardiology
information resource reference: 2011 ACCF/AHA guideline for the diagnosis and treatment of hypertrophic cardiomyopathy: executive summary: a report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines. J Am Coll Cardiol. 2011 Dec 13; 58(25):2703-38.
journal title abbreviation: J Am Coll Cardiol
publication date: 2011-11-08T00:00:00
year: 2011
type: Academic Article
type: Article
type: Document
type: Information Resource
label: 2011 ACCF/AHA guideline for the diagnosis and treatment of hypertrophic cardiomyopathy: executive summary: a report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines.

CD36 overexpression predisposes to arrhythmias but reduces infarct size in spontaneously hypertensive rats: gene expression profile analysis.
PubMed Identifier: 22128087
author list: Neckár J, Šilhavy J, Zídek V, Landa V, Mlejnek P, Šimáková M, Seidman JG, Seidman C, Kazdová L, Klevstig M, Novák F, Vecka M, Papoušek F, Houštek J, Drahota Z, Kurtz TW, Kolár F, Pravenec M
published in: Physiological genomics
information resource reference: CD36 overexpression predisposes to arrhythmias but reduces infarct size in spontaneously hypertensive rats: gene expression profile analysis. Physiol Genomics. 2012 Feb 01; 44(2):173-82.
journal title abbreviation: Physiol Genomics
publication date: 2011-11-29T00:00:00
year: 2011
type: Academic Article
type: Article
type: Document
type: Information Resource

https://connects.catalyst.harvard.edu/Profiles/profile/957087
PubMed Identifier: 22068435
author list: Gersh BJ, Maron BJ, Bonow RO, Dearani JA, Fifer MA, Link MS, Naidu SS, Nishimura RA, Ommen SR, Rakowski H, Seidman CE, Towbin JA, Udelson JE, Yancy CW
published in: Circulation
information resource reference: 2011 ACCF/AHA guideline for the diagnosis and treatment of hypertrophic cardiomyopathy: executive summary: a report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines. Circulation. 2011 Dec 13; 124(24):2761-96.
journal title abbreviation: Circulation
publication date: 2011-11-08T00:00:00
year: 2011
type: Academic Article
type: Article
type: Document
type: Information Resource
label: 2011 ACCF/AHA guideline for the diagnosis and treatment of hypertrophic cardiomyopathy: executive summary: a report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines.

Proatrial natriuretic factor is phosphorylated by rat cardiocytes in culture.
PubMed Identifier: 2956256
author list: Bloch KD, Jones SW, Preibisch G, Seipke G, Seidman CE, Seidman JG
published in: The Journal of biological chemistry
information resource reference: Proatrial natriuretic factor is phosphorylated by rat cardiocytes in culture. J Biol Chem. 1987 Jul 25; 262(21):9956-61.
journal title abbreviation: J Biol Chem
publication date: 1987-07-25T00:00:00
year: 1987
type: Academic Article
type: Article
type: Document
type: Information Resource

Inhospital CPR 25 years later: why has survival decreased?
PubMed Identifier: 4049035
author list: Dans PE, Nevin KL, Seidman CE, McArthur JC, Kariya ST
published in: Southern medical journal
information resource reference: Inhospital CPR 25 years later: why has survival decreased? South Med J. 1985 Oct; 78(10):1174-8.
journal title abbreviation: South Med J
publication date: 1985-10-01T00:00:00
year: 1985
type: Academic Article
type: Article
type: Document
type: Information Resource

Nucleotide sequences of the human and mouse atrial natriuretic factor genes.
PubMed Identifier: 6542248
author list: Seidman CE, Bloch KD, Klein KA, Smith JA, Seidman JG
published in: Science (New York, N.Y.)
information resource reference: Nucleotide sequences of the human and mouse atrial natriuretic factor genes. Science. 1984 Dec 07; 226(4679):1206-9.
journal title abbreviation: Science
publication date: 1984-12-07T00:00:00
year: 1984
type: Academic Article
type: Article
type: Document
type: Information Resource

Leptospirosis.
PubMed Identifier: 7412068
author list: Seidman CE, Murphy PA
published in: The Johns Hopkins medical journal
information resource reference: Leptospirosis. Johns Hopkins Med J. 1980 Aug; 147(2):65-9.
journal title abbreviation: Johns Hopkins Med J
publication date: 1980-08-01T00:00:00
year: 1980
type: Academic Article
type: Article
type: Document
type: Information Resource

Functional analysis of myosin missense mutations in familial hypertrophic cardiomyopathy.
PubMed Identifier: 8290568
author list: Straceski AJ, Geisterfer-Lowrance A, Seidman CE, Seidman JG, Leinwand LA
published in: Proceedings of the National Academy of Sciences of the United States of America
information resource reference: Functional analysis of myosin missense mutations in familial hypertrophic cardiomyopathy. Proc Natl Acad Sci U S A. 1994 Jan 18; 91(2):589-93.
journal title abbreviation: Proc Natl Acad Sci U S A
publication date: 1994-01-18T00:00:00
year: 1994
type: Academic Article
type: Article
type: Document
type: Information Resource

Locus for familial migrainous vertigo disease maps to chromosome 5q35.
PubMed Identifier: 19810609
author list: Bahmad F, DePalma SR, Merchant SN, Bezerra RL, Oliveira CA, Seidman CE, Seidman JG
published in: The Annals of otology, rhinology, and laryngology
information resource reference: Locus for familial migrainous vertigo disease maps to chromosome 5q35. Ann Otol Rhinol Laryngol. 2009 Sep; 118(9):670-6.
journal title abbreviation: Ann Otol Rhinol Laryngol
publication date: 2009-09-01T00:00:00
year: 2009
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1037163
type: Authorship
author rank in publication: 9
linked author: Seidman, Christine
linked information resource: A Novel Role for CSRP1 in a Lebanese Family with Congenital Cardiac Defects.

Authorship 1037842
type: Authorship
author rank in publication: 10
linked author: Seidman, Christine
linked information resource: Force Generation via ß-Cardiac Myosin, Titin, and a-Actinin Drives Cardiac Sarcomere Assembly from Cell-Matrix Adhesions.

A Novel Role for CSRP1 in a Lebanese Family with Congenital Cardiac Defects.
PubMed Identifier: 29326753
author list: Kamar A, Fahed AC, Shibbani K, El-Hachem N, Bou-Slaiman S, Arabi M, Kurban M, Seidman JG, Seidman CE, Haidar R, Baydoun E, Nemer G, Bitar F
published in: Frontiers in genetics
information resource reference: A Novel Role for CSRP1 in a Lebanese Family with Congenital Cardiac Defects. Front Genet. 2017; 8:217.
journal title abbreviation: Front Genet
publication date: 2017-12-18T00:00:00
year: 2017
type: Academic Article
type: Article
type: Document
type: Information Resource

Force Generation via ß-Cardiac Myosin, Titin, and a-Actinin Drives Cardiac Sarcomere Assembly from Cell-Matrix Adhesions.
PubMed Identifier: 29316444
author list: Chopra A, Kutys ML, Zhang K, Polacheck WJ, Sheng CC, Luu RJ, Eyckmans J, Hinson JT, Seidman JG, Seidman CE, Chen CS
published in: Developmental cell
information resource reference: Force Generation via ß-Cardiac Myosin, Titin, and a-Actinin Drives Cardiac Sarcomere Assembly from Cell-Matrix Adhesions. Dev Cell. 2018 01 08; 44(1):87-96.e5.
journal title abbreviation: Dev Cell
publication date: 2018-01-08T00:00:00
year: 2018
type: Academic Article
type: Article
type: Document
type: Information Resource

Differentiation and Contractile Analysis of GFP-Sarcomere Reporter hiPSC-Cardiomyocytes.
PubMed Identifier: 29364522
author list: Sharma A, Toepfer CN, Schmid M, Garfinkel AC, Seidman CE
published in: Current protocols in human genetics
information resource reference: Differentiation and Contractile Analysis of GFP-Sarcomere Reporter hiPSC-Cardiomyocytes. Curr Protoc Hum Genet. 2018 01 24; 96:21.12.1-21.12.12.
journal title abbreviation: Curr Protoc Hum Genet
publication date: 2018-01-24T00:00:00
year: 2018
type: Academic Article
type: Article
type: Document
type: Information Resource

CRISPR/Cas9-Mediated Fluorescent Tagging of Endogenous Proteins in Human Pluripotent Stem Cells.
PubMed Identifier: 29364519
author list: Sharma A, Toepfer CN, Ward T, Wasson L, Agarwal R, Conner DA, Hu JH, Seidman CE
published in: Current protocols in human genetics
information resource reference: CRISPR/Cas9-Mediated Fluorescent Tagging of Endogenous Proteins in Human Pluripotent Stem Cells. Curr Protoc Hum Genet. 2018 01 24; 96:21.11.1-21.11.20.
journal title abbreviation: Curr Protoc Hum Genet
publication date: 2018-01-24T00:00:00
year: 2018
type: Academic Article
type: Article
type: Document
type: Information Resource

Hypertrophic and dilated cardiomyopathy mutations differentially affect the molecular force generation of mouse alpha-cardiac myosin in the laser trap assay.
PubMed Identifier: 17351073
author list: Debold EP, Schmitt JP, Patlak JB, Beck SE, Moore JR, Seidman JG, Seidman C, Warshaw DM
published in: American journal of physiology. Heart and circulatory physiology
information resource reference: Hypertrophic and dilated cardiomyopathy mutations differentially affect the molecular force generation of mouse alpha-cardiac myosin in the laser trap assay. Am J Physiol Heart Circ Physiol. 2007 Jul; 293(1):H284-91.
journal title abbreviation: Am J Physiol Heart Circ Physiol
publication date: 2007-03-09T00:00:00
year: 2007
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1040472
type: Authorship
author rank in publication: 8
linked author: Seidman, Christine
linked information resource: ViroFind: A novel target-enrichment deep-sequencing platform reveals a complex JC virus population in the brain of PML patients.

ViroFind: A novel target-enrichment deep-sequencing platform reveals a complex JC virus population in the brain of PML patients.
PubMed Identifier: 29360822
author list: Chalkias S, Gorham JM, Mazaika E, Parfenov M, Dang X, DePalma S, McKean D, Seidman CE, Seidman JG, Koralnik IJ
published in: PloS one
information resource reference: ViroFind: A novel target-enrichment deep-sequencing platform reveals a complex JC virus population in the brain of PML patients. PLoS One. 2018; 13(1):e0186945.
journal title abbreviation: PLoS One
publication date: 2018-01-23T00:00:00
year: 2018
type: Academic Article
type: Article
type: Document
type: Information Resource

Genetics of hypertrophic cardiomyopathy.
PubMed Identifier: 20124998
author list: Konno T, Chang S, Seidman JG, Seidman CE
published in: Current opinion in cardiology
information resource reference: Genetics of hypertrophic cardiomyopathy. Curr Opin Cardiol. 2010 May; 25(3):205-9.
journal title abbreviation: Curr Opin Cardiol
publication date: 2010-05-01T00:00:00
year: 2010
type: Academic Article
type: Article
type: Document
type: Information Resource

Prevention of ventricular arrhythmia and calcium dysregulation in a catecholaminergic polymorphic ventricular tachycardia mouse model carrying calsequestrin-2 mutation.
PubMed Identifier: 20807279
author list: Alcalai R, Wakimoto H, Arad M, Planer D, Konno T, Wang L, Seidman JG, Seidman CE, Berul CI
published in: Journal of cardiovascular electrophysiology
information resource reference: Prevention of ventricular arrhythmia and calcium dysregulation in a catecholaminergic polymorphic ventricular tachycardia mouse model carrying calsequestrin-2 mutation. J Cardiovasc Electrophysiol. 2011 Mar; 22(3):316-24.
journal title abbreviation: J Cardiovasc Electrophysiol
publication date: 2010-08-30T00:00:00
year: 2010
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1043045
type: Authorship
author rank in publication: 5
linked author: Seidman, Christine
linked information resource: Differentiation and Contractile Analysis of GFP-Sarcomere Reporter hiPSC-Cardiomyocytes.

Regulation of chamber-specific gene expression in the developing heart by Irx4.
PubMed Identifier: 10024241
author list: Bao ZZ, Bruneau BG, Seidman JG, Seidman CE, Cepko CL
published in: Science (New York, N.Y.)
information resource reference: Regulation of chamber-specific gene expression in the developing heart by Irx4. Science. 1999 Feb 19; 283(5405):1161-4.
journal title abbreviation: Science
publication date: 1999-02-19T00:00:00
year: 1999
type: Academic Article
type: Article
type: Document
type: Information Resource

Missense mutations in the rod domain of the lamin A/C gene as causes of dilated cardiomyopathy and conduction-system disease.
PubMed Identifier: 10580070
author list: Fatkin D, MacRae C, Sasaki T, Wolff MR, Porcu M, Frenneaux M, Atherton J, Vidaillet HJ, Spudich S, De Girolami U, Seidman JG, Seidman C, Muntoni F, Müehle G, Johnson W, McDonough B
published in: The New England journal of medicine
information resource reference: Missense mutations in the rod domain of the lamin A/C gene as causes of dilated cardiomyopathy and conduction-system disease. N Engl J Med. 1999 Dec 02; 341(23):1715-24.
journal title abbreviation: N Engl J Med
publication date: 1999-12-02T00:00:00
year: 1999
type: Academic Article
type: Article
type: Document
type: Information Resource

Single-molecule mechanics of R403Q cardiac myosin isolated from the mouse model of familial hypertrophic cardiomyopathy.
PubMed Identifier: 10764406
author list: Tyska MJ, Hayes E, Giewat M, Seidman CE, Seidman JG, Warshaw DM
published in: Circulation research
information resource reference: Single-molecule mechanics of R403Q cardiac myosin isolated from the mouse model of familial hypertrophic cardiomyopathy. Circ Res. 2000 Apr 14; 86(7):737-44.
journal title abbreviation: Circ Res
publication date: 2000-04-14T00:00:00
year: 2000
type: Academic Article
type: Article
type: Document
type: Information Resource

A nonsense mutation in MSX1 causes Witkop syndrome.
PubMed Identifier: 11369996
author list: Jumlongras D, Bei M, Stimson JM, Wang WF, DePalma SR, Seidman CE, Felbor U, Maas R, Seidman JG, Olsen BR
published in: American journal of human genetics
information resource reference: A nonsense mutation in MSX1 causes Witkop syndrome. Am J Hum Genet. 2001 Jul; 69(1):67-74.
journal title abbreviation: Am J Hum Genet
publication date: 2001-05-16T00:00:00
year: 2001
type: Academic Article
type: Article
type: Document
type: Information Resource

The L-type calcium channel inhibitor diltiazem prevents cardiomyopathy in a mouse model.
PubMed Identifier: 11956238
author list: Semsarian C, Ahmad I, Giewat M, Georgakopoulos D, Schmitt JP, McConnell BK, Reiken S, Mende U, Marks AR, Kass DA, Seidman CE, Seidman JG
published in: The Journal of clinical investigation
information resource reference: The L-type calcium channel inhibitor diltiazem prevents cardiomyopathy in a mouse model. J Clin Invest. 2002 Apr; 109(8):1013-20.
journal title abbreviation: J Clin Invest
publication date: 2002-04-01T00:00:00
year: 2002
type: Academic Article
type: Article
type: Document
type: Information Resource

Proximal regulatory domains of rat atrial natriuretic factor gene.
PubMed Identifier: 1832094
author list: Rosenzweig A, Halazonetis TD, Seidman JG, Seidman CE
published in: Circulation
information resource reference: Proximal regulatory domains of rat atrial natriuretic factor gene. Circulation. 1991 Sep; 84(3):1256-65.
journal title abbreviation: Circulation
publication date: 1991-09-01T00:00:00
year: 1991
type: Academic Article
type: Article
type: Document
type: Information Resource

Differential cross-bridge kinetics of FHC myosin mutations R403Q and R453C in heterozygous mouse myocardium.
PubMed Identifier: 15001446
author list: Palmer BM, Fishbaugher DE, Schmitt JP, Wang Y, Alpert NR, Seidman CE, Seidman JG, VanBuren P, Maughan DW
published in: American journal of physiology. Heart and circulatory physiology
information resource reference: Differential cross-bridge kinetics of FHC myosin mutations R403Q and R453C in heterozygous mouse myocardium. Am J Physiol Heart Circ Physiol. 2004 Jul; 287(1):H91-9.
journal title abbreviation: Am J Physiol Heart Circ Physiol
publication date: 2004-03-04T00:00:00
year: 2004
type: Academic Article
type: Article
type: Document
type: Information Resource

QTL influencing autoimmune diabetes and encephalomyelitis map to a 0.15-cM region containing Il2.
PubMed Identifier: 9988264
author list: Encinas JA, Wicker LS, Peterson LB, Mukasa A, Teuscher C, Sobel R, Weiner HL, Seidman CE, Seidman JG, Kuchroo VK
published in: Nature genetics
information resource reference: QTL influencing autoimmune diabetes and encephalomyelitis map to a 0.15-cM region containing Il2. Nat Genet. 1999 Feb; 21(2):158-60.
journal title abbreviation: Nat Genet
publication date: 1999-02-01T00:00:00
year: 1999
type: Academic Article
type: Article
type: Document
type: Information Resource

Electrophysiologic characteristics of accessory atrioventricular connections in an inherited form of Wolff-Parkinson-White syndrome.
PubMed Identifier: 10355918
author list: Mehdirad AA, Fatkin D, DiMarco JP, MacRae CA, Wase A, Seidman JG, Seidman CE, Benson DW
published in: Journal of cardiovascular electrophysiology
information resource reference: Electrophysiologic characteristics of accessory atrioventricular connections in an inherited form of Wolff-Parkinson-White syndrome. J Cardiovasc Electrophysiol. 1999 May; 10(5):629-35.
journal title abbreviation: J Cardiovasc Electrophysiol
publication date: 1999-05-01T00:00:00
year: 1999
type: Academic Article
type: Article
type: Document
type: Information Resource

Genetic testing for dilated cardiomyopathy in clinical practice.
PubMed Identifier: 22464770
author list: Lakdawala NK, Funke BH, Baxter S, Cirino AL, Roberts AE, Judge DP, Johnson N, Mendelsohn NJ, Morel C, Care M, Chung WK, Jones C, Psychogios A, Duffy E, Rehm HL, White E, Seidman JG, Seidman CE, Ho CY
published in: Journal of cardiac failure
information resource reference: Genetic testing for dilated cardiomyopathy in clinical practice. J Card Fail. 2012 Apr; 18(4):296-303.
journal title abbreviation: J Card Fail
publication date: 2012-02-15T00:00:00
year: 2012
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 100530
type: Authorship
author rank in publication: 8
linked author: Seidman, Christine
linked information resource: Molecular epidemiology of hypertrophic cardiomyopathy.

Effects of two familial hypertrophic cardiomyopathy-causing mutations on alpha-tropomyosin structure and function
PubMed Identifier: 10090775
author list: Golitsina N, An Y, Greenfield NJ, Thierfelder L, Iizuka K, Seidman JG, Seidman CE, Lehrer SS, Hitchcock-DeGregori SE
published in: Biochemistry
information resource reference: Effects of two familial hypertrophic cardiomyopathy-causing mutations on alpha-tropomyosin structure and function Biochemistry. 1999 Mar 23; 38(12):3850.
journal title abbreviation: Biochemistry
publication date: 1999-03-23T00:00:00
year: 1999
type: Academic Article
type: Article
type: Document
type: Information Resource

Mutations in COCH (formerly Coch5b2) cause DFNA9.
PubMed Identifier: 10868220
author list: Eavey RD, Manolis EN, Lubianca J, Merchant S, Seidman JG, Seidman C
published in: Advances in oto-rhino-laryngology
information resource reference: Mutations in COCH (formerly Coch5b2) cause DFNA9. Adv Otorhinolaryngol. 2000; 56:101-2.
journal title abbreviation: Adv Otorhinolaryngol
publication date: 2000-01-01T00:00:00
year: 2000
type: Academic Article
type: Article
type: Document
type: Information Resource

Various types of hereditary inclusion body myopathies map to chromosome 9p1-q1.
PubMed Identifier: 9124813
author list: Argov Z, Tiram E, Eisenberg I, Sadeh M, Seidman CE, Seidman JG, Karpati G, Mitrani-Rosenbaum S
published in: Annals of neurology
information resource reference: Various types of hereditary inclusion body myopathies map to chromosome 9p1-q1. Ann Neurol. 1997 Apr; 41(4):548-51.
journal title abbreviation: Ann Neurol
publication date: 1997-04-01T00:00:00
year: 1997
type: Academic Article
type: Article
type: Document
type: Information Resource

Cao-sensing receptor (CaR)-mediated activation of K+ channels is blunted in CaR gene-deficient mouse neurons.
PubMed Identifier: 9172145
author list: Vassilev PM, Ho-Pao CL, Kanazirska MP, Ye C, Hong K, Seidman CE, Seidman JG, Brown EM
published in: Neuroreport
information resource reference: Cao-sensing receptor (CaR)-mediated activation of K+ channels is blunted in CaR gene-deficient mouse neurons. Neuroreport. 1997 Apr 14; 8(6):1411-6.
journal title abbreviation: Neuroreport
publication date: 1997-04-14T00:00:00
year: 1997
type: Academic Article
type: Article
type: Document
type: Information Resource

Human fatty acid synthesis is reduced after the substitution of dietary starch for sugar.
PubMed Identifier: 9537610
author list: Hudgins LC, Seidman CE, Diakun J, Hirsch J
published in: The American journal of clinical nutrition
information resource reference: Human fatty acid synthesis is reduced after the substitution of dietary starch for sugar. Am J Clin Nutr. 1998 Apr; 67(4):631-9.
journal title abbreviation: Am J Clin Nutr
publication date: 1998-04-01T00:00:00
year: 1998
type: Academic Article
type: Article
type: Document
type: Information Resource