An improved washing apparatus for nucleoside phosphorylation assays. Biotechniques. 1993 Sep; 15(3):402-4, 406.
An improved washing apparatus for nucleoside phosphorylation assays.
D'Amato RJ, Lentzsch S, Anderson KC, Rogers MS
Mechanism of action of thalidomide and 3-aminothalidomide in multiple myeloma. Semin Oncol. 2001 Dec; 28(6):597-601.
Mechanism of action of thalidomide and 3-aminothalidomide in multiple myeloma.
Dao DT, Anez-Bustillos L, Ourieff J, Pan A, Mitchell PD, Kishikawa H, Fell GL, Baker MA, Watnick RS, Chen H, Hamilton TE, Rogers MS, Bielenberg DR, Puder M
Heparin impairs angiogenic signaling and compensatory lung growth after left pneumonectomy. Angiogenesis. 2018 11; 21(4):837-848.
Heparin impairs angiogenic signaling and compensatory lung growth after left pneumonectomy.
Nakai K, Rogers MS, Baba T, Funakoshi T, Birsner AE, Luyindula DS, D'Amato RJ
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Genetic loci that control the size of laser-induced choroidal neovascularization. FASEB J. 2009 Jul; 23(7):2235-43.
Genetic loci that control the size of laser-induced choroidal neovascularization.
Rogers MS, Boyartchuk V, Rohan RM, Birsner AE, Dietrich WF, D'Amato RJ
The classical pink-eyed dilution mutation affects angiogenic responsiveness. PLoS One. 2012; 7(5):e35237.
The classical pink-eyed dilution mutation affects angiogenic responsiveness.
Cao S, Cryan L, Habeshian KA, Murillo C, Tamayo-Castillo G, Rogers MS, Clardy J
Bioorganic & medicinal chemistry letters
Phenolic compounds as antiangiogenic CMG2 inhibitors from Costa Rican endophytic fungi. Bioorg Med Chem Lett. 2012 Sep 15; 22(18):5885-8.
Phenolic compounds as antiangiogenic CMG2 inhibitors from Costa Rican endophytic fungi.
Lentzsch S, Rogers MS, LeBlanc R, Birsner AE, Shah JH, Treston AM, Anderson KC, D'Amato RJ
S-3-Amino-phthalimido-glutarimide inhibits angiogenesis and growth of B-cell neoplasias in mice. Cancer Res. 2002 Apr 15; 62(8):2300-5.
S-3-Amino-phthalimido-glutarimide inhibits angiogenesis and growth of B-cell neoplasias in mice.
Rogers MS, Rohan RM, Birsner AE, D'Amato RJ
Genetic loci that control vascular endothelial growth factor-induced angiogenesis. FASEB J. 2003 Nov; 17(14):2112-4.
Genetic loci that control vascular endothelial growth factor-induced angiogenesis.
Dao DT, Anez-Bustillos L, Jabbouri SS, Pan A, Kishikawa H, Mitchell PD, Fell GL, Baker MA, Watnick RS, Chen H, Rogers MS, Bielenberg DR, Puder M
A paradoxical method to enhance compensatory lung growth: Utilizing a VEGF inhibitor. PLoS One. 2018; 13(12):e0208579.
A paradoxical method to enhance compensatory lung growth: Utilizing a VEGF inhibitor.
Cryan LM, Habeshian KA, Caldwell TP, Morris MT, Ackroyd PC, Christensen KA, Rogers MS
Identification of small molecules that inhibit the interaction of TEM8 with anthrax protective antigen using a FRET assay. J Biomol Screen. 2013 Jul; 18(6):714-25.
Identification of small molecules that inhibit the interaction of TEM8 with anthrax protective antigen using a FRET assay.
Ghalali A, Rice JM, Kusztos A, Jernigan FE, Zetter BR, Rogers MS
Developing a novel FRET assay, targeting the binding between Antizyme-AZIN. Sci Rep. 2019 03 15; 9(1):4632.
Developing a novel FRET assay, targeting the binding between Antizyme-AZIN.
G-Doyagüez E, Carrero P, Madrona A, Rodriguez-Salamanca P, Martínez-Gualda B, Camarasa MJ, Jimeno ML, Bennallack PR, Finnell JG, Tsang TM, Christensen KA, San-Félix A, Rogers MS
Galloyl Carbohydrates with Antiangiogenic Activity Mediated by Capillary Morphogenesis Gene 2 (CMG2) Protein Binding. J Med Chem. 2019 04 25; 62(8):3958-3970.
Galloyl Carbohydrates with Antiangiogenic Activity Mediated by Capillary Morphogenesis Gene 2 (CMG2) Protein Binding.
Harvard T.H. Chan School of Public Health
Maude and Lillian Presley Professor of Microbiology and Immunobiology, Emeritus
Charles Nowiszewski Professor of Cancer Biology in the Department of Surgery
Julia Dyckman Andrus Professor of Surgery
Claes H. Dohlman Professor of Ophthalmology
A. Werk Cook Professor of Radiation Oncology (Tumor Biology)
Fattori V, Franklin NS, Gonzalez-Cano R, Peterse D, Ghalali A, Madrian E, Verri WA, Andrews N, Woolf CJ, Rogers MS
Nonsurgical mouse model of endometriosis-associated pain that responds to clinically active drugs. Pain. 2020 06; 161(6):1321-1331.
Nonsurgical mouse model of endometriosis-associated pain that responds to clinically active drugs.
Van Egeren D, Novokhodko A, Stoddard M, Tran U, Zetter B, Rogers MS, Joseph-McCarthy D, Chakravarty A
Controlling long-term SARS-CoV-2 infections can slow viral evolution and reduce the risk of treatment failure. Sci Rep. 2021 11 19; 11(1):22630.
Controlling long-term SARS-CoV-2 infections can slow viral evolution and reduce the risk of treatment failure.
Van Egeren D, Stoddard M, Novokhodko A, Rogers MS, Joseph-McCarthy D, Zetter B, Chakravarty A
Rapid relaxation of pandemic restrictions after vaccine rollout favors growth of SARS-CoV-2 variants: A model-based analysis. PLoS One. 2021; 16(11):e0258997.
Rapid relaxation of pandemic restrictions after vaccine rollout favors growth of SARS-CoV-2 variants: A model-based analysis.
Finnell JG, Tsang TM, Cryan L, Garrard S, Lee SL, Ackroyd PC, Rogers MS, Christensen KA
A Canstatin-Derived Peptide Provides Insight into the Role of Capillary Morphogenesis Gene 2 in Angiogenic Regulation and Matrix Uptake. ACS Chem Biol. 2020 02 21; 15(2):587-596.
A Canstatin-Derived Peptide Provides Insight into the Role of Capillary Morphogenesis Gene 2 in Angiogenic Regulation and Matrix Uptake.
Cryan LM, Tsang TM, Stiles J, Bazinet L, Lee SL, Garrard S, Madrian E, Roberts C, Payne J, Jensen A, Frankel AE, Ackroyd PC, Christensen KA, Rogers MS
Capillary morphogenesis gene 2 (CMG2) mediates growth factor-induced angiogenesis by regulating endothelial cell chemotaxis. Angiogenesis. 2022 08; 25(3):397-410.
Capillary morphogenesis gene 2 (CMG2) mediates growth factor-induced angiogenesis by regulating endothelial cell chemotaxis.
Zaninelli TH, Fattori V, Saraiva-Santos T, Badaro-Garcia S, Staurengo-Ferrari L, Andrade KC, Artero NA, Ferraz CR, Bertozzi MM, Rasquel-Oliveira F, Manchope MF, Amaral FA, Teixeira MM, Borghi SM, Rogers MS, Casagrande R, Verri WA
RvD1 disrupts nociceptor neuron and macrophage activation and neuroimmune communication, reducing pain and inflammation in gouty arthritis in mice. Br J Pharmacol. 2022 09; 179(18):4500-4515.
RvD1 disrupts nociceptor neuron and macrophage activation and neuroimmune communication, reducing pain and inflammation in gouty arthritis in mice.
Ghalali A, Wang L, Stopsack KH, Rice JM, Wu S, Wu CL, Zetter BR, Rogers MS
AZIN1 RNA editing alters protein interactions, leading to nuclear translocation and worse outcomes in prostate cancer. Exp Mol Med. 2022 10; 54(10):1713-1726.
AZIN1 RNA editing alters protein interactions, leading to nuclear translocation and worse outcomes in prostate cancer.
Saraiva-Santos T, Zaninelli TH, Manchope MF, Andrade KC, Ferraz CR, Bertozzi MM, Artero NA, Franciosi A, Badaro-Garcia S, Staurengo-Ferrari L, Borghi SM, Ceravolo GS, Andrello AC, Zanoveli JM, Rogers MS, Casagrande R, Pinho-Ribeiro FA, Verri WA
Therapeutic activity of lipoxin A4 in TiO2-induced arthritis in mice: NF-?B and Nrf2 in synovial fluid leukocytes and neuronal TRPV1 mechanisms. Front Immunol. 2023; 14:949407.
Therapeutic activity of lipoxin A4 in TiO2-induced arthritis in mice: NF-?B and Nrf2 in synovial fluid leukocytes and neuronal TRPV1 mechanisms.
Van Egeren D, Stoddard M, White LF, Hochberg NS, Rogers MS, Zetter B, Joseph-McCarthy D, Chakravarty A
Vaccines Alone Cannot Slow the Evolution of SARS-CoV-2. Vaccines (Basel). 2023 Apr 16; 11(4).
Vaccines Alone Cannot Slow the Evolution of SARS-CoV-2.
Functional requirement of CMG2 for endothelial cell chemotaxis and resulting angiogenesis
Identification of a Novel Target for the Treatment of Endometriosis-associated Pain
Zaninelli TH, Fattori V, Heintz OK, Wright KR, Bennallack PR, Sim D, Bukhari H, Terry KL, Vitonis AF, Missmer SA, Andrello AC, Anchan RM, Godin SK, Bree D, Verri WA, Rogers MS
Targeting NGF but not VEGFR1 or BDNF signaling reduces endometriosis-associated pain in mice. J Adv Res. 2025 Jul; 73:593-605.
Targeting NGF but not VEGFR1 or BDNF signaling reduces endometriosis-associated pain in mice.
Rogers MS, Adini I, McBride AF, Birsner AE, D'Amato RJ
The albino mutation of tyrosinase alters ocular angiogenic responsiveness. Angiogenesis. 2013 Jul; 16(3):639-46.
The albino mutation of tyrosinase alters ocular angiogenic responsiveness.
Fattori V, Zaninelli TH, Rasquel-Oliveira FS, Heintz OK, Jain A, Sun L, Seshan ML, Peterse D, Lindholm AE, Anchan RM, Verri WA, Rogers MS
Nociceptor-to-macrophage communication through CGRP/RAMP1 signaling drives endometriosis-associated pain and lesion growth in mice. Sci Transl Med. 2024 11 06; 16(772):eadk8230.
Nociceptor-to-macrophage communication through CGRP/RAMP1 signaling drives endometriosis-associated pain and lesion growth in mice.
Ochoa S, Rasquel-Oliveira FS, McKinnon B, Haro M, Subramaniam S, Yu P, Coetzee S, Anglesio MS, Wright KN, Meyer R, Gargett CE, Mortlock S, Montgomery GW, Rogers MS, Lawrenson K
bioRxiv : the preprint server for biology
M2 Macrophages are Major Mediators of Germline Risk of Endometriosis and Explain Pleiotropy with Comorbid Traits. bioRxiv. 2024 Nov 22.
M2 Macrophages are Major Mediators of Germline Risk of Endometriosis and Explain Pleiotropy with Comorbid Traits.
Bharath N, DiPietro E, Durfee O, Kycia I, Splaine J, Sethupathy P, Rogers MS, Vakili K
SLAS discovery : advancing life sciences R & D
A novel high-throughput screening platform to identify inhibitors of DNAJB1-PRKACA-driven transcriptional activity in fibrolamellar carcinoma. SLAS Discov. 2025 04; 32:100221.
A novel high-throughput screening platform to identify inhibitors of DNAJB1-PRKACA-driven transcriptional activity in fibrolamellar carcinoma.
Yuan L, Stoddard M, Sarkar S, Egeren DV, Mangalaganesh S, Nolan RP, Rogers MS, Hather G, White LF, Chakravarty A
The Impact of Vaccination Frequency on COVID-19 Public Health Outcomes: A Model-Based Analysis. Vaccines (Basel). 2025 Mar 30; 13(4).
The Impact of Vaccination Frequency on COVID-19 Public Health Outcomes: A Model-Based Analysis.
Proceedings of the National Academy of Sciences of the United States of America
Pomalidomide is strongly antiangiogenic and teratogenic in relevant animal models. Proc Natl Acad Sci U S A. 2013 Dec 10; 110(50):E4818.
Pomalidomide is strongly antiangiogenic and teratogenic in relevant animal models.
Adini I, Ghosh K, Adini A, Chi ZL, Yoshimura T, Benny O, Connor KM, Rogers MS, Bazinet L, Birsner AE, Bielenberg DR, D'Amato RJ
Melanocyte-secreted fibromodulin promotes an angiogenic microenvironment. J Clin Invest. 2014 Jan; 124(1):425-36.
Melanocyte-secreted fibromodulin promotes an angiogenic microenvironment.
CMG2 as a target for safe and effective treatment of endometriosis-associate pain
Rogers MS, Novak K, Zurakowski D, Cryan LM, Blois A, Lifshits E, Bø TH, Oyan AM, Bender ER, Lampa M, Kang SY, Naxerova K, Kalland KH, Straume O, Akslen LA, Watnick RS, Folkman J, Naumov GN
Spontaneous reversion of the angiogenic phenotype to a nonangiogenic and dormant state in human tumors. Mol Cancer Res. 2014 May; 12(5):754-64.
Spontaneous reversion of the angiogenic phenotype to a nonangiogenic and dormant state in human tumors.
Are 90% of deaths from cancer caused by metastases? Cancer Med. 2019 Sep; 8(12):5574-5576.
Are 90% of deaths from cancer caused by metastases?
Boccia T, Pan W, Fattori V, Cervantes-Diaz R, Rogers MS, Zanoni I, Cuenca AG
Adjuvant conditioning shapes the adaptive immune response promoting immunotolerance via NLRP3/interleukin-1. iScience. 2025 Jun 20; 28(6):112653.
Adjuvant conditioning shapes the adaptive immune response promoting immunotolerance via NLRP3/interleukin-1.
Dodds KN, Fattori V, Andrews NA, Appleyard CB, Christianson JA, Gomez R, McAllister SL, Missmer SA, Nagel J, Nunez-Badinez P, Rogers MS, Saunders PTK, Tejada MA, Vincent K, Hummelshoj L, Bruner-Tran KL, Greaves E
WERF Endometriosis Phenome and Biobanking Harmonisation Project for Experimental Models in Endometriosis Research (EPHect-EM-Pain): methods to assess pain behaviour in rodent models of endometriosis. Mol Hum Reprod. 2025 Jul 03; 31(3).
WERF Endometriosis Phenome and Biobanking Harmonisation Project for Experimental Models in Endometriosis Research (EPHect-EM-Pain): methods to assess pain behaviour in rodent models of endometriosis.
Burns KA, Peterse D, Appleyard CB, Chandler R, Guo SW, Pearson A, Persoons E, Anglesio MS, Rogers MS, Sharpe-Timms KL, Vriens J, McAllister SL, Dodds KN, Cousins FL, Hummelshoj L, Missmer SA, Bruner-Tran KL, Greaves E
WERF Endometriosis Phenome and Biobanking Harmonisation Project for Experimental Models in Endometriosis Research (EPHect-EM-Homologous): homologous rodent models. Mol Hum Reprod. 2025 Jul 03; 31(3).
WERF Endometriosis Phenome and Biobanking Harmonisation Project for Experimental Models in Endometriosis Research (EPHect-EM-Homologous): homologous rodent models.
Jiang F, Mongre RK, Truman J, de Oliveira R, Hardy E, Hardy E, Fowler J, Wang C, Lin HL, Rose ZJ, Kelly RT, Ackroyd PC, Rogers MS, Christensen KA
CMG2 interaction with actin is required for growth factor-induced chemotaxis in endothelial cells. bioRxiv. 2025 Jul 24.
CMG2 interaction with actin is required for growth factor-induced chemotaxis in endothelial cells.
Boccia T, Fattori V, Veloso Da Silva MD, Asquith NL, Pan W, Rogers MS, Zanoni I, Cuenca AG
Journal of immunology (Baltimore, Md. : 1950)
Adjuvant conditioning enhances neutrophil function while inducing a suppressive peritoneal macrophage phenotype. J Immunol. 2025 Dec 01; 214(12):3604-3617.
Adjuvant conditioning enhances neutrophil function while inducing a suppressive peritoneal macrophage phenotype.
Boccia T, Veloso da Silva MD, Fattori V, Pan W, Rogers MS, Cuenca AG
Protocol for modeling innate immune training by repeated alum exposure in mice (adjuvant conditioning). STAR Protoc. 2026 Mar 20; 7(1):104390.
Protocol for modeling innate immune training by repeated alum exposure in mice (adjuvant conditioning).
Ochoa S, Rasquel-Oliveira FS, McKinnon B, Haro M, Subramaniam S, Yu P, Coetzee S, Anglesio MS, Wright KN, Meyer R, Porter AE, Gargett CE, Mortlock S, Montgomery GW, Rogers MS, Lawrenson K
Advanced science (Weinheim, Baden-Wurttemberg, Germany)
M2 Macrophages are Major Mediators of Germline Risk of Endometriosis and Explain Pleiotropy With Comorbid Traits. Adv Sci (Weinh). 2025 Nov; 12(41):e15285.
M2 Macrophages are Major Mediators of Germline Risk of Endometriosis and Explain Pleiotropy With Comorbid Traits.
Fattori V, Rasquel-Oliveira FS, Ochoa S, Graf E, Bazzano MV, Aung T, Vural M, Kohl C, Solano ME, da Silva MDV, Heintz OK, Brierley SM, Verri WA, Haerteis S, Castro J, Lawrenson K, Rogers MS
Pro-endometriosis macrophage release of IL-33 is key for endometriosis pain and lesion formation. bioRxiv. 2025 Oct 21.
Pro-endometriosis macrophage release of IL-33 is key for endometriosis pain and lesion formation.
Endometriosis. Semin Reprod Med. 2025 Sep; 43(3):165-166.
Novel Angiogenesis Inhibitors Targeting the Anthrax Toxin Receptors
Assay for Inhibitors of Angiogenesis and Anthrax Toxin Receptor 1
Assays to Identify Prostate Cancer Therapeutics Targeting Antizyme Inhibitor
Thalidomide for multiple myeloma. N Engl J Med. 2006 Jun 01; 354(22):2389-90; author reply 2389-90.
Qian H, Rogers MS, Schleucher J, Edlund U, Strehler EE, Sethson I
Protein science : a publication of the Protein Society
Sequential assignment of 1H, 15N, 13C resonances and secondary structure of human calmodulin-like protein determined by NMR spectroscopy. Protein Sci. 1998 Nov; 7(11):2421-30.
Sequential assignment of 1H, 15N, 13C resonances and secondary structure of human calmodulin-like protein determined by NMR spectroscopy.
Shaked Y, Bertolini F, Man S, Rogers MS, Cervi D, Foutz T, Rawn K, Voskas D, Dumont DJ, Ben-David Y, Lawler J, Henkin J, Huber J, Hicklin DJ, D'Amato RJ, Kerbel RS
Genetic heterogeneity of the vasculogenic phenotype parallels angiogenesis; Implications for cellular surrogate marker analysis of antiangiogenesis. Cancer Cell. 2005 Jan; 7(1):101-11.
Genetic heterogeneity of the vasculogenic phenotype parallels angiogenesis; Implications for cellular surrogate marker analysis of antiangiogenesis.
Genetic loci that control the angiogenic response to basic fibroblast growth factor. FASEB J. 2004 Jul; 18(10):1050-9.
Genetic loci that control the angiogenic response to basic fibroblast growth factor.
Khajavi M, Zhou Y, Birsner AE, Bazinet L, Rosa Di Sant A, Schiffer AJ, Rogers MS, Krishnaji ST, Hu B, Nguyen V, Zon L, D'Amato RJ
Identification of Padi2 as a novel angiogenesis-regulating gene by genome association studies in mice. PLoS Genet. 2017 Jun; 13(6):e1006848.
Identification of Padi2 as a novel angiogenesis-regulating gene by genome association studies in mice.
Rogers MS, Kobayashi T, Pittelkow MR, Strehler EE
Human calmodulin-like protein is an epithelial-specific protein regulated during keratinocyte differentiation. Exp Cell Res. 2001 Jul 15; 267(2):216-24.
Human calmodulin-like protein is an epithelial-specific protein regulated during keratinocyte differentiation.
Frontiers in bioscience (Landmark edition)
Targeting the anthrax receptors, TEM-8 and CMG-2, for anti-angiogenic therapy. Front Biosci (Landmark Ed). 2011 01 01; 16(4):1574-88.
Targeting the anthrax receptors, TEM-8 and CMG-2, for anti-angiogenic therapy.
Rogers MS, Christensen KA, Birsner AE, Short SM, Wigelsworth DJ, Collier RJ, D'Amato RJ
Mutant anthrax toxin B moiety (protective antigen) inhibits angiogenesis and tumor growth. Cancer Res. 2007 Oct 15; 67(20):9980-5.
Mutant anthrax toxin B moiety (protective antigen) inhibits angiogenesis and tumor growth.
Cold Spring Harbor perspectives in medicine
Common polymorphisms in angiogenesis. Cold Spring Harb Perspect Med. 2012 Nov 01; 2(11).
The effect of genetic diversity on angiogenesis. Exp Cell Res. 2006 Mar 10; 312(5):561-74.
The effect of genetic diversity on angiogenesis.
Rogers MS, Foley MA, Crotty TB, Hartmann LC, Ingle JN, Roche PC, Strehler EE
Loss of immunoreactivity for human calmodulin-like protein is an early event in breast cancer development. Neoplasia. 1999 Aug; 1(3):220-5.
Loss of immunoreactivity for human calmodulin-like protein is an early event in breast cancer development.
The tumor-sensitive calmodulin-like protein is a specific light chain of human unconventional myosin X. J Biol Chem. 2001 Apr 13; 276(15):12182-9.
The tumor-sensitive calmodulin-like protein is a specific light chain of human unconventional myosin X.
Browder T, Folkman J, Hahnfeldt P, Heymach J, Hlatky L, Kieran M, Rogers MS
Antiangiogenic therapy and p53. Science. 2002 Jul 26; 297(5581):471; discussion 471.
Cryan LM, Bazinet L, Habeshian KA, Cao S, Clardy J, Christensen KA, Rogers MS
1,2,3,4,6-Penta-O-galloyl-ß-D-glucopyranose inhibits angiogenesis via inhibition of capillary morphogenesis gene 2. J Med Chem. 2013 Mar 14; 56(5):1940-5.
1,2,3,4,6-Penta-O-galloyl-ß-D-glucopyranose inhibits angiogenesis via inhibition of capillary morphogenesis gene 2.
Rogers MS, Cryan LM, Habeshian KA, Bazinet L, Caldwell TP, Ackroyd PC, Christensen KA
A FRET-based high throughput screening assay to identify inhibitors of anthrax protective antigen binding to capillary morphogenesis gene 2 protein. PLoS One. 2012; 7(6):e39911.
A FRET-based high throughput screening assay to identify inhibitors of anthrax protective antigen binding to capillary morphogenesis gene 2 protein.
The mouse cornea micropocket angiogenesis assay. Nat Protoc. 2007; 2(10):2545-50.
The mouse cornea micropocket angiogenesis assay.
Garamszegi N, Garamszegi ZP, Rogers MS, DeMarco SJ, Strehler EE
Application of a chimeric green fluorescent protein to study protein-protein interactions. Biotechniques. 1997 Nov; 23(5):864-6, 868-70, 872.
Application of a chimeric green fluorescent protein to study protein-protein interactions.