Cellular and molecular biology (Noisy-le-Grand, France)
Expression of functional Na,K-ATPase isozymes in normal human cardiac biopsies. Cell Mol Biol (Noisy-le-grand). 2001 Mar; 47(2):265-71.
Expression of functional Na,K-ATPase isozymes in normal human cardiac biopsies.
Rossi D, Simeoni I, Micheli M, Bootman M, Lipp P, Allen PD, Sorrentino V
RyR1 and RyR3 isoforms provide distinct intracellular Ca2+ signals in HEK 293 cells. J Cell Sci. 2002 06 15; 115(Pt 12):2497-504.
RyR1 and RyR3 isoforms provide distinct intracellular Ca2+ signals in HEK 293 cells.
Allen PD, López JR, Sánchez V, Ryan JF, Sreter FA
EU 4093 decreases intracellular [Ca2+] in skeletal muscle fibers from control and malignant hyperthermia-susceptible swine. Anesthesiology. 1992 Jan; 76(1):132-8.
EU 4093 decreases intracellular [Ca2+] in skeletal muscle fibers from control and malignant hyperthermia-susceptible swine.
Physostigmine: effectiveness as an antagonist of respiratory depression and psychomotor effects caused by morphine or diazepam. Anesthesiology. 1984 Nov; 61(5):523-8.
Physostigmine: effectiveness as an antagonist of respiratory depression and psychomotor effects caused by morphine or diazepam.
Christensen RA, Shtifman A, Allen PD, Lopez JR, Querfurth HW
Calcium dyshomeostasis in beta-amyloid and tau-bearing skeletal myotubes. J Biol Chem. 2004 Dec 17; 279(51):53524-32.
Calcium dyshomeostasis in beta-amyloid and tau-bearing skeletal myotubes.
Lopez JR, Alamo LA, Jones DE, Papp L, Allen PD, Gergely J, Sréter FA
[Ca2+]i in muscles of malignant hyperthermia susceptible pigs determined in vivo with Ca2+ selective microelectrodes. Muscle Nerve. 1986 Jan; 9(1):85-6.
[Ca2+]i in muscles of malignant hyperthermia susceptible pigs determined in vivo with Ca2+ selective microelectrodes.
Krausz MM, Utsunomiya T, McIrvine AJ, Allen PD, Levine L, Mannick JA, Shepro D, Hechtman HB
Modulation of cardiovascular function and platelet survival by endogenous prostacyclin released during surgery. Surgery. 1983 Apr; 93(4):554-9.
Modulation of cardiovascular function and platelet survival by endogenous prostacyclin released during surgery.
Anderson PA, Greig A, Mark TM, Malouf NN, Oakeley AE, Ungerleider RM, Allen PD, Kay BK
Molecular basis of human cardiac troponin T isoforms expressed in the developing, adult, and failing heart. Circ Res. 1995 Apr; 76(4):681-6.
Molecular basis of human cardiac troponin T isoforms expressed in the developing, adult, and failing heart.
Hübner N, Kreutz R, Rubattu S, Lee YA, Ganten D, Allen PD, Lindpaintner K
Mammalian genome : official journal of the International Mammalian Genome Society
The gene encoding endothelial nitric oxide synthase, Nos3, maps to rat chromosome 4. Mamm Genome. 1995 Oct; 6(10):758-9.
The gene encoding endothelial nitric oxide synthase, Nos3, maps to rat chromosome 4.
Expression of A-, B-, and C-type natriuretic peptide genes in failing and developing human ventricles. Correlation with expression of the Ca(2+)-ATPase gene. Circ Res. 1992 Jul; 71(1):9-17.
Expression of A-, B-, and C-type natriuretic peptide genes in failing and developing human ventricles. Correlation with expression of the Ca(2+)-ATPase gene.
Paolini C, Quarta M, Nori A, Boncompagni S, Canato M, Volpe P, Allen PD, Reggiani C, Protasi F
Reorganized stores and impaired calcium handling in skeletal muscle of mice lacking calsequestrin-1. J Physiol. 2007 Sep 01; 583(Pt 2):767-84.
Reorganized stores and impaired calcium handling in skeletal muscle of mice lacking calsequestrin-1.
Feng W, Tu J, Yang T, Vernon PS, Allen PD, Worley PF, Pessah IN
Homer regulates gain of ryanodine receptor type 1 channel complex. J Biol Chem. 2002 Nov 22; 277(47):44722-30.
Homer regulates gain of ryanodine receptor type 1 channel complex.
Zhu X, Ghanta J, Walker JW, Allen PD, Valdivia HH
The calmodulin binding region of the skeletal ryanodine receptor acts as a self-modulatory domain. Cell Calcium. 2004 Feb; 35(2):165-77.
The calmodulin binding region of the skeletal ryanodine receptor acts as a self-modulatory domain.
Anderson PA, Malouf NN, Oakeley AE, Pagani ED, Allen PD
Troponin T isoform expression in humans. A comparison among normal and failing adult heart, fetal heart, and adult and fetal skeletal muscle. Circ Res. 1991 Nov; 69(5):1226-33.
Troponin T isoform expression in humans. A comparison among normal and failing adult heart, fetal heart, and adult and fetal skeletal muscle.
Denniss AR, Colucci WS, Allen PD, Marsh JD
Journal of molecular and cellular cardiology
Distribution and function of human ventricular beta adrenergic receptors in congestive heart failure. J Mol Cell Cardiol. 1989 Jul; 21(7):651-60.
Distribution and function of human ventricular beta adrenergic receptors in congestive heart failure.
Jacobsen DC, Soden KJ, Allen PD, Daicoff GR
Humoral blockade on lethal pulmonary embolism in the awake dog. Surg Forum. 1971; 22:209-11.
Humoral blockade on lethal pulmonary embolism in the awake dog.
Kim DH, Sreter FA, Ohnishi ST, Ryan JF, Roberts J, Allen PD, Meszaros LG, Antoniu B, Ikemoto N
Kinetic studies of Ca2+ release from sarcoplasmic reticulum of normal and malignant hyperthermia susceptible pig muscles. Biochim Biophys Acta. 1984 Sep 05; 775(3):320-7.
Kinetic studies of Ca2+ release from sarcoplasmic reticulum of normal and malignant hyperthermia susceptible pig muscles.
Shen X, Franzini-Armstrong C, Lopez JR, Jones LR, Kobayashi YM, Wang Y, Kerrick WG, Caswell AH, Potter JD, Miller T, Allen PD, Perez CF
Triadins modulate intracellular Ca(2+) homeostasis but are not essential for excitation-contraction coupling in skeletal muscle. J Biol Chem. 2007 Dec 28; 282(52):37864-74.
Triadins modulate intracellular Ca(2+) homeostasis but are not essential for excitation-contraction coupling in skeletal muscle.
Homo-dimerization of RyR1 C-terminus via charged residues in random coils or in an alpha-helix. Exp Mol Med. 2007 Oct 31; 39(5):594-602.
Homo-dimerization of RyR1 C-terminus via charged residues in random coils or in an alpha-helix.
Coordinated movement of cytoplasmic and transmembrane domains of RyR1 upon gating. PLoS Biol. 2009 Apr 14; 7(4):e85.
Coordinated movement of cytoplasmic and transmembrane domains of RyR1 upon gating.
Contractility effects of local anesthetics in the presence of sodium channel blockade. Reg Anesth. 1989 Mar-Apr; 14(2):58-62.
Contractility effects of local anesthetics in the presence of sodium channel blockade.
Bannister RA, Estève E, Eltit JM, Pessah IN, Allen PD, López JR, Beam KG
A malignant hyperthermia-inducing mutation in RYR1 (R163C): consequent alterations in the functional properties of DHPR channels. J Gen Physiol. 2010 Jun; 135(6):629-40.
A malignant hyperthermia-inducing mutation in RYR1 (R163C): consequent alterations in the functional properties of DHPR channels.
Kashiyama T, Murayama T, Suzuki E, Allen PD, Ogawa Y
Frog alpha- and beta-ryanodine receptors provide distinct intracellular Ca2+ signals in a myogenic cell line. PLoS One. 2010 Jul 12; 5(7):e11526.
Frog alpha- and beta-ryanodine receptors provide distinct intracellular Ca2+ signals in a myogenic cell line.
RyR1/RyR3 chimeras reveal that multiple domains of RyR1 are involved in skeletal-type E-C coupling. Biophys J. 2003 Apr; 84(4):2655-63.
RyR1/RyR3 chimeras reveal that multiple domains of RyR1 are involved in skeletal-type E-C coupling.
Protasi F, Shtifman A, Julian FJ, Allen PD
American journal of physiology. Cell physiology
All three ryanodine receptor isoforms generate rapid cooling responses in muscle cells. Am J Physiol Cell Physiol. 2004 Mar; 286(3):C662-70.
All three ryanodine receptor isoforms generate rapid cooling responses in muscle cells.
Dos Remedios CG, Liew CC, Allen PD, Winslow RL, Van Eyk JE, Dunn MJ
Journal of muscle research and cell motility
Genomics, proteomics and bioinformatics of human heart failure. J Muscle Res Cell Motil. 2003; 24(4-6):251-60.
Genomics, proteomics and bioinformatics of human heart failure.
Lee EH, Song DW, Lee JM, Meissner G, Allen PD, Kim DH
Biochemical and biophysical research communications
Occurrence of atypical Ca2+ transients in triadin-binding deficient-RYR1 mutants. Biochem Biophys Res Commun. 2006 Dec 29; 351(4):909-14.
Occurrence of atypical Ca2+ transients in triadin-binding deficient-RYR1 mutants.
Morgan JP, Erny RE, Allen PD, Grossman W, Gwathmey JK
Abnormal intracellular calcium handling, a major cause of systolic and diastolic dysfunction in ventricular myocardium from patients with heart failure. Circulation. 1990 Feb; 81(2 Suppl):III21-32.
Abnormal intracellular calcium handling, a major cause of systolic and diastolic dysfunction in ventricular myocardium from patients with heart failure.
Estève E, Eltit JM, Bannister RA, Liu K, Pessah IN, Beam KG, Allen PD, López JR
A malignant hyperthermia-inducing mutation in RYR1 (R163C): alterations in Ca2+ entry, release, and retrograde signaling to the DHPR. J Gen Physiol. 2010 Jun; 135(6):619-28.
A malignant hyperthermia-inducing mutation in RYR1 (R163C): alterations in Ca2+ entry, release, and retrograde signaling to the DHPR.
Szpyt J, Lorenzon N, Perez CF, Norris E, Allen PD, Beam KG, Samsó M
Three-dimensional localization of the a and ß subunits and of the II-III loop in the skeletal muscle L-type Ca2+ channel. J Biol Chem. 2012 Dec 21; 287(52):43853-61.
Three-dimensional localization of the a and ß subunits and of the II-III loop in the skeletal muscle L-type Ca2+ channel.
López JR, Allen PD, Alamo L, Jones D, Sreter FA
Myoplasmic free [Ca2+] during a malignant hyperthermia episode in swine. Muscle Nerve. 1988 Jan; 11(1):82-8.
Myoplasmic free [Ca2+] during a malignant hyperthermia episode in swine.
Stomper PC, Kopans DB, Sadowsky NL, Sonnenfeld MR, Swann CA, Gelman RS, Meyer JE, Jochelson MS, Hunt MS, Allen PD
Is mammography painful? A multicenter patient survey. Arch Intern Med. 1988 Mar; 148(3):521-4.
Is mammography painful? A multicenter patient survey.
Bourke DL, Allen PD, Rosenberg M, Mendes RW, Karabelas AN
Dextroamphetamine with morphine: respiratory effects. J Clin Pharmacol. 1983 Jan; 23(1):65-70.
Dextroamphetamine with morphine: respiratory effects.
Lopez JR, Sanchez V, Lopez I, Ryan JF, Mendoza M, Sreter FA, Allen PD
The effects of extracellular magnesium on myoplasmic [Ca2+] in malignant hyperthermia susceptible swine. Anesthesiology. 1990 Jul; 73(1):109-17.
The effects of extracellular magnesium on myoplasmic [Ca2+] in malignant hyperthermia susceptible swine.
Allen PD, Ryan JF, Jones DE, Mabuchi K, Virga A, Roberts J, Sreter F
Sarcoplasmic reticulum calcium uptake in cryostat sections of skeletal muscle from malignant hyperthermia patients and controls. Muscle Nerve. 1986 Jun; 9(5):474-5.
Sarcoplasmic reticulum calcium uptake in cryostat sections of skeletal muscle from malignant hyperthermia patients and controls.
Triadin, not essential, but useful. J Physiol. 2009 Jul 01; 587(Pt 13):3123-4.
Salgado DM, Eltit JM, Mansfield K, Panqueba C, Castro D, Vega MR, Xhaja K, Schmidt D, Martin KJ, Allen PD, Rodriguez JA, Dinsmore JH, López JR, Bosch I
The Pediatric infectious disease journal
Heart and skeletal muscle are targets of dengue virus infection. Pediatr Infect Dis J. 2010 Mar; 29(3):238-42.
Heart and skeletal muscle are targets of dengue virus infection.
Chopra N, Yang T, Asghari P, Moore ED, Huke S, Akin B, Cattolica RA, Perez CF, Hlaing T, Knollmann-Ritschel BE, Jones LR, Pessah IN, Allen PD, Franzini-Armstrong C, Knollmann BC
Proceedings of the National Academy of Sciences of the United States of America
Ablation of triadin causes loss of cardiac Ca2+ release units, impaired excitation-contraction coupling, and cardiac arrhythmias. Proc Natl Acad Sci U S A. 2009 May 05; 106(18):7636-41.
Ablation of triadin causes loss of cardiac Ca2+ release units, impaired excitation-contraction coupling, and cardiac arrhythmias.
Eltit JM, Yang T, Li H, Molinski TF, Pessah IN, Allen PD, Lopez JR
RyR1-mediated Ca2+ leak and Ca2+ entry determine resting intracellular Ca2+ in skeletal myotubes. J Biol Chem. 2010 Apr 30; 285(18):13781-7.
RyR1-mediated Ca2+ leak and Ca2+ entry determine resting intracellular Ca2+ in skeletal myotubes.
Enhanced excitation-coupled calcium entry in myotubes is associated with expression of RyR1 malignant hyperthermia mutations. J Biol Chem. 2007 Dec 28; 282(52):37471-8.
Enhanced excitation-coupled calcium entry in myotubes is associated with expression of RyR1 malignant hyperthermia mutations.
Cherednichenko G, Ward CW, Feng W, Cabrales E, Michaelson L, Samso M, López JR, Allen PD, Pessah IN
Enhanced excitation-coupled calcium entry in myotubes expressing malignant hyperthermia mutation R163C is attenuated by dantrolene. Mol Pharmacol. 2008 Apr; 73(4):1203-12.
Enhanced excitation-coupled calcium entry in myotubes expressing malignant hyperthermia mutation R163C is attenuated by dantrolene.
Utsunomiya T, Krausz MM, Dunham B, Mannick JA, Allen PD, Shepro D, Hechtman HB
Maintenance of cardiodynamics with aspirin during abdominal aortic aneurysmectomy (AAA). Ann Surg. 1981 Nov; 194(5):602-8.
Maintenance of cardiodynamics with aspirin during abdominal aortic aneurysmectomy (AAA).
Nakai J, Dirksen RT, Nguyen HT, Pessah IN, Beam KG, Allen PD
Enhanced dihydropyridine receptor channel activity in the presence of ryanodine receptor. Nature. 1996 Mar 07; 380(6569):72-5.
Enhanced dihydropyridine receptor channel activity in the presence of ryanodine receptor.
Hamman BL, Bittl JA, Jacobus WE, Allen PD, Spencer RS, Tian R, Ingwall JS
Inhibition of the creatine kinase reaction decreases the contractile reserve of isolated rat hearts. Am J Physiol. 1995 Sep; 269(3 Pt 2):H1030-6.
Inhibition of the creatine kinase reaction decreases the contractile reserve of isolated rat hearts.
The relationship between temperature and oxygen uptake of contracting skeletal muscle. Med Sci Sports. 1974; 6(1):33-7.
The relationship between temperature and oxygen uptake of contracting skeletal muscle.
MacKinnon R, Gwathmey JK, Allen PD, Briggs GM, Morgan JP
Modulation by the thyroid state of intracellular calcium and contractility in ferret ventricular muscle. Circ Res. 1988 Dec; 63(6):1080-9.
Modulation by the thyroid state of intracellular calcium and contractility in ferret ventricular muscle.
Allen PD, Walman T, Concepcion M, Sheskey M, Patterson MK, Cullen D, Covino BG
Epidural morphine provides postoperative pain relief in peripheral vascular and orthopedic surgical patients: a dose-response study. Anesth Analg. 1986 Feb; 65(2):165-70.
Epidural morphine provides postoperative pain relief in peripheral vascular and orthopedic surgical patients: a dose-response study.
Glass MG, Fuleihan F, Liao R, Lincoff AM, Chapados R, Hamlin R, Apstein CS, Allen PD, Ingwall JS, Hajjar RJ
Differences in cardioprotective efficacy of adrenergic receptor antagonists and Ca2+ channel antagonists in an animal model of dilated cardiomyopathy. Effects on gross morphology, global cardiac function, and twitch force. Circ Res. 1993 Dec; 73(6):1077-89.
Differences in cardioprotective efficacy of adrenergic receptor antagonists and Ca2+ channel antagonists in an animal model of dilated cardiomyopathy. Effects on gross morphology, global cardiac function, and twitch force.
Schmidt TA, Allen PD, Colucci WS, Marsh JD, Kjeldsen K
No adaptation to digitalization as evaluated by digitalis receptor (Na,K-ATPase) quantification in explanted hearts from donors without heart disease and from digitalized recipients with end-stage heart failure. Am J Cardiol. 1993 Jan 01; 71(1):110-4.
No adaptation to digitalization as evaluated by digitalis receptor (Na,K-ATPase) quantification in explanted hearts from donors without heart disease and from digitalized recipients with end-stage heart failure.
Huval WV, Lelcuk S, Allen PD, Mannick JA, Shepro D, Hechtman HB
Determinants of cardiovascular stability during abdominal aortic aneurysmectomy (AAA). Ann Surg. 1984 Feb; 199(2):216-22.
Determinants of cardiovascular stability during abdominal aortic aneurysmectomy (AAA).
Perreault CL, Hague NL, Morgan KG, Allen PD, Morgan JP
Negative inotropic and relaxant effects of cocaine on myopathic human ventricular myocardium and epicardial coronary arteries in vitro. Cardiovasc Res. 1993 Feb; 27(2):262-8.
Negative inotropic and relaxant effects of cocaine on myopathic human ventricular myocardium and epicardial coronary arteries in vitro.
Sheridan DC, Takekura H, Franzini-Armstrong C, Beam KG, Allen PD, Perez CF
Bidirectional signaling between calcium channels of skeletal muscle requires multiple direct and indirect interactions. Proc Natl Acad Sci U S A. 2006 Dec 26; 103(52):19760-5.
Bidirectional signaling between calcium channels of skeletal muscle requires multiple direct and indirect interactions.
Ryan JF, Lopez JR, Sanchez VB, Sréter FA, Allen PD
Myoplasmic calcium changes precede metabolic and clinical signs of porcine malignant hyperthermia. Anesth Analg. 1994 Nov; 79(5):1007-11.
Myoplasmic calcium changes precede metabolic and clinical signs of porcine malignant hyperthermia.
Hasenfuss G, Mulieri LA, Allen PD, Just H, Alpert NR
Influence of isoproterenol and ouabain on excitation-contraction coupling, cross-bridge function, and energetics in failing human myocardium. Circulation. 1996 Dec 15; 94(12):3155-60.
Influence of isoproterenol and ouabain on excitation-contraction coupling, cross-bridge function, and energetics in failing human myocardium.
Mulieri LA, Leavitt BJ, Hasenfuss G, Allen PD, Alpert NR
Contraction frequency dependence of twitch and diastolic tension in human dilated cardiomyopathy (tension-frequency relation in cardiomyopathy). Basic Res Cardiol. 1992; 87 Suppl 1:199-212.
Contraction frequency dependence of twitch and diastolic tension in human dilated cardiomyopathy (tension-frequency relation in cardiomyopathy).
Ward CW, Schneider MF, Castillo D, Protasi F, Wang Y, Chen SR, Allen PD
Expression of ryanodine receptor RyR3 produces Ca2+ sparks in dyspedic myotubes. J Physiol. 2000 May 15; 525 Pt 1:91-103.
Expression of ryanodine receptor RyR3 produces Ca2+ sparks in dyspedic myotubes.
Chen L, Estève E, Sabatier JM, Ronjat M, De Waard M, Allen PD, Pessah IN
Maurocalcine and peptide A stabilize distinct subconductance states of ryanodine receptor type 1, revealing a proportional gating mechanism. J Biol Chem. 2003 May 02; 278(18):16095-106.
Maurocalcine and peptide A stabilize distinct subconductance states of ryanodine receptor type 1, revealing a proportional gating mechanism.
Not all sudden death is the same. Circ Res. 2003 Sep 19; 93(6):484-6.
Jacobson AR, Moe ST, Allen PD, Fessenden JD
Structural determinants of 4-chloro-m-cresol required for activation of ryanodine receptor type 1. Mol Pharmacol. 2006 Jul; 70(1):259-66.
Structural determinants of 4-chloro-m-cresol required for activation of ryanodine receptor type 1.
TRPC3-interacting triadic proteins in skeletal muscle. Biochem J. 2008 Apr 15; 411(2):399-405.
TRPC3-interacting triadic proteins in skeletal muscle.
Westerman KA, Penvose A, Yang Z, Allen PD, Vacanti CA
Adult muscle 'stem' cells can be sustained in culture as free-floating myospheres. Exp Cell Res. 2010 Jul 15; 316(12):1966-76.
Adult muscle 'stem' cells can be sustained in culture as free-floating myospheres.
Eltit JM, Szpyt J, Li H, Allen PD, Perez CF
Reduced gain of excitation-contraction coupling in triadin-null myotubes is mediated by the disruption of FKBP12/RyR1 interaction. Cell Calcium. 2011 Feb; 49(2):128-35.
Reduced gain of excitation-contraction coupling in triadin-null myotubes is mediated by the disruption of FKBP12/RyR1 interaction.
Ryanodine Receptor Calcium Release Channel
Vandam/Covino Professor of Anaesthesia, Emeritus
Professor of Medicine (Physiology), Emerita
Professor of Obstetrics, Gynecology and Reproductive Biology, Emerita
George H. A. Clowes, Jr. Distinguished Professor of Surgery
Professor of Orthopedic Surgery (Biomaterials), Emeritus
Nancy Lurie Marks Professor of Neurology
Aldo R. Castaneda Professor of Cardiovascular Research, Emeritus
Feng W, Barrientos GC, Cherednichenko G, Yang T, Padilla IT, Truong K, Allen PD, Lopez JR, Pessah IN
Functional and biochemical properties of ryanodine receptor type 1 channels from heterozygous R163C malignant hyperthermia-susceptible mice. Mol Pharmacol. 2011 Mar; 79(3):420-31.
Functional and biochemical properties of ryanodine receptor type 1 channels from heterozygous R163C malignant hyperthermia-susceptible mice.
Giulivi C, Ross-Inta C, Omanska-Klusek A, Napoli E, Sakaguchi D, Barrientos G, Allen PD, Pessah IN
Basal bioenergetic abnormalities in skeletal muscle from ryanodine receptor malignant hyperthermia-susceptible R163C knock-in mice. J Biol Chem. 2011 Jan 07; 286(1):99-113.
Basal bioenergetic abnormalities in skeletal muscle from ryanodine receptor malignant hyperthermia-susceptible R163C knock-in mice.
Manno C, Sztretye M, Figueroa L, Allen PD, Ríos E
Dynamic measurement of the calcium buffering properties of the sarcoplasmic reticulum in mouse skeletal muscle. J Physiol. 2013 Jan 15; 591(2):423-42.
Dynamic measurement of the calcium buffering properties of the sarcoplasmic reticulum in mouse skeletal muscle.
Cai WF, Pritchard T, Florea S, Lam CK, Han P, Zhou X, Yuan Q, Lehnart SE, Allen PD, Kranias EG
Ablation of junctin or triadin is associated with increased cardiac injury following ischaemia/reperfusion. Cardiovasc Res. 2012 May 01; 94(2):333-41.
Ablation of junctin or triadin is associated with increased cardiac injury following ischaemia/reperfusion.
Olojo RO, Ziman AP, Hernández-Ochoa EO, Allen PD, Schneider MF, Ward CW
Mice null for calsequestrin 1 exhibit deficits in functional performance and sarcoplasmic reticulum calcium handling. PLoS One. 2011; 6(12):e27036.
Mice null for calsequestrin 1 exhibit deficits in functional performance and sarcoplasmic reticulum calcium handling.
Eltit JM, Bannister RA, Moua O, Altamirano F, Hopkins PM, Pessah IN, Molinski TF, López JR, Beam KG, Allen PD
Malignant hyperthermia susceptibility arising from altered resting coupling between the skeletal muscle L-type Ca2+ channel and the type 1 ryanodine receptor. Proc Natl Acad Sci U S A. 2012 May 15; 109(20):7923-8.
Malignant hyperthermia susceptibility arising from altered resting coupling between the skeletal muscle L-type Ca2+ channel and the type 1 ryanodine receptor.
Eltit JM, Li H, Ward CW, Molinski T, Pessah IN, Allen PD, Lopez JR
Orthograde dihydropyridine receptor signal regulates ryanodine receptor passive leak. Proc Natl Acad Sci U S A. 2011 Apr 26; 108(17):7046-51.
Orthograde dihydropyridine receptor signal regulates ryanodine receptor passive leak.
Li H, Ding X, Lopez JR, Takeshima H, Ma J, Allen PD, Eltit JM
Impaired Orai1-mediated resting Ca2+ entry reduces the cytosolic [Ca2+] and sarcoplasmic reticulum Ca2+ loading in quiescent junctophilin 1 knock-out myotubes. J Biol Chem. 2010 Dec 10; 285(50):39171-9.
Impaired Orai1-mediated resting Ca2+ entry reduces the cytosolic [Ca2+] and sarcoplasmic reticulum Ca2+ loading in quiescent junctophilin 1 knock-out myotubes.
MOLECULAR &ENVIRONMENTAL FACTORS INFLUENCING MH
Mechanisms controlling Ca2+ dyshomeostasis in MH susceptible mice
Dihydropyridine receptors and slow calcium signals
Structure Function Studies of RyR1 in a Myogenic Knockout
Muscle: Excitation/Contraction Coupling Gordon Research Conference
E-C Coupling: Signaling Between Calcium Channels
Integral membrane protein overexpression using organ bioreactors
Uncovering the Molecular Basis of Malignant Hyperthermia
Tunwell RE, Wickenden C, Bertrand BM, Shevchenko VI, Walsh MB, Allen PD, Lai FA
The human cardiac muscle ryanodine receptor-calcium release channel: identification, primary structure and topological analysis. Biochem J. 1996 Sep 01; 318 ( Pt 2):477-87.
The human cardiac muscle ryanodine receptor-calcium release channel: identification, primary structure and topological analysis.
Nascimben L, Ingwall JS, Pauletto P, Friedrich J, Gwathmey JK, Saks V, Pessina AC, Allen PD
Creatine kinase system in failing and nonfailing human myocardium. Circulation. 1996 Oct 15; 94(8):1894-901.
Creatine kinase system in failing and nonfailing human myocardium.
Nakai J, Ogura T, Protasi F, Franzini-Armstrong C, Allen PD, Beam KG
Functional nonequality of the cardiac and skeletal ryanodine receptors. Proc Natl Acad Sci U S A. 1997 Feb 04; 94(3):1019-22.
Functional nonequality of the cardiac and skeletal ryanodine receptors.
Pessah IN, Molinski TF, Meloy TD, Wong P, Buck ED, Allen PD, Mohr FC, Mack MM
Bastadins relate ryanodine-sensitive and -insensitive Ca2+ efflux pathways in skeletal SR and BC3H1 cells. Am J Physiol. 1997 Feb; 272(2 Pt 1):C601-14.
Bastadins relate ryanodine-sensitive and -insensitive Ca2+ efflux pathways in skeletal SR and BC3H1 cells.
López JR, Cordovez G, Linares N, Allen PD
Pflugers Archiv : European journal of physiology
Cyclic ADP-ribose induces a larger than normal calcium release in malignant hyperthermia-susceptible skeletal muscle fibers. Pflugers Arch. 2000 Jun; 440(2):236-42.
Cyclic ADP-ribose induces a larger than normal calcium release in malignant hyperthermia-susceptible skeletal muscle fibers.
Wang Y, Camp SM, Niwano M, Shen X, Bakowska JC, Breakefield XO, Allen PD
Herpes simplex virus type 1/adeno-associated virus rep(+) hybrid amplicon vector improves the stability of transgene expression in human cells by site-specific integration. J Virol. 2002 Jul; 76(14):7150-62.
Herpes simplex virus type 1/adeno-associated virus rep(+) hybrid amplicon vector improves the stability of transgene expression in human cells by site-specific integration.
Fessenden JD, Perez CF, Goth S, Pessah IN, Allen PD
Identification of a key determinant of ryanodine receptor type 1 required for activation by 4-chloro-m-cresol. J Biol Chem. 2003 Aug 01; 278(31):28727-35.
Identification of a key determinant of ryanodine receptor type 1 required for activation by 4-chloro-m-cresol.
Nakashima Y, Nishimura S, Maeda A, Barsoumian EL, Hakamata Y, Nakai J, Allen PD, Imoto K, Kita T
Molecular cloning and characterization of a human brain ryanodine receptor. FEBS Lett. 1997 Nov 03; 417(1):157-62.
Molecular cloning and characterization of a human brain ryanodine receptor.
Transmembrane redox sensor of ryanodine receptor complex. J Biol Chem. 2000 Nov 17; 275(46):35902-7.
Transmembrane redox sensor of ryanodine receptor complex.
Fessenden JD, Feng W, Pessah IN, Allen PD
Mutational analysis of putative calcium binding motifs within the skeletal ryanodine receptor isoform, RyR1. J Biol Chem. 2004 Dec 17; 279(51):53028-35.
Mutational analysis of putative calcium binding motifs within the skeletal ryanodine receptor isoform, RyR1.
Yang T, Riehl J, Esteve E, Matthaei KI, Goth S, Allen PD, Pessah IN, Lopez JR
Pharmacologic and functional characterization of malignant hyperthermia in the R163C RyR1 knock-in mouse. Anesthesiology. 2006 Dec; 105(6):1164-75.
Pharmacologic and functional characterization of malignant hyperthermia in the R163C RyR1 knock-in mouse.
Sainte Beuve C, Allen PD, Dambrin G, Rannou F, Marty I, Trouvé P, Bors V, Pavie A, Gandgjbakch I, Charlemagne D
Cardiac calcium release channel (ryanodine receptor) in control and cardiomyopathic human hearts: mRNA and protein contents are differentially regulated. J Mol Cell Cardiol. 1997 Apr; 29(4):1237-46.
Cardiac calcium release channel (ryanodine receptor) in control and cardiomyopathic human hearts: mRNA and protein contents are differentially regulated.
Fessenden JD, Chen L, Wang Y, Paolini C, Franzini-Armstrong C, Allen PD, Pessah IN
Ryanodine receptor point mutant E4032A reveals an allosteric interaction with ryanodine. Proc Natl Acad Sci U S A. 2001 Feb 27; 98(5):2865-70.
Ryanodine receptor point mutant E4032A reveals an allosteric interaction with ryanodine.
Bowling N, Huang X, Sandusky GE, Fouts RL, Mintze K, Esterman M, Allen PD, Maddi R, McCall E, Vlahos CJ
Protein kinase C-alpha and -epsilon modulate connexin-43 phosphorylation in human heart. J Mol Cell Cardiol. 2001 Apr; 33(4):789-98.
Protein kinase C-alpha and -epsilon modulate connexin-43 phosphorylation in human heart.
Hasenfuss G, Mulieri LA, Leavitt BJ, Allen PD, Haeberle JR, Alpert NR
Alteration of contractile function and excitation-contraction coupling in dilated cardiomyopathy. Circ Res. 1992 Jun; 70(6):1225-32.
Alteration of contractile function and excitation-contraction coupling in dilated cardiomyopathy.
Medford RM, Hyman R, Ahmad M, Allen JC, Pressley TA, Allen PD, Nadal-Ginard B
Vascular smooth muscle expresses a truncated Na+, K(+)-ATPase alpha-1 subunit isoform. J Biol Chem. 1991 Sep 25; 266(27):18308-12.
Vascular smooth muscle expresses a truncated Na+, K(+)-ATPase alpha-1 subunit isoform.
Ikeda S, Kong SW, Lu J, Bisping E, Zhang H, Allen PD, Golub TR, Pieske B, Pu WT
Altered microRNA expression in human heart disease. Physiol Genomics. 2007 Nov 14; 31(3):367-73.
Altered microRNA expression in human heart disease.
Allosterically coupled calcium and magnesium binding sites are unmasked by ryanodine receptor chimeras. Biochem Biophys Res Commun. 2008 Feb 22; 366(4):988-93.
Allosterically coupled calcium and magnesium binding sites are unmasked by ryanodine receptor chimeras.
Proenza C, O'Brien J, Nakai J, Mukherjee S, Allen PD, Beam KG
Identification of a region of RyR1 that participates in allosteric coupling with the alpha(1S) (Ca(V)1.1) II-III loop. J Biol Chem. 2002 Feb 22; 277(8):6530-5.
Identification of a region of RyR1 that participates in allosteric coupling with the alpha(1S) (Ca(V)1.1) II-III loop.
Anesthesia and the human genome project: the quest for accurate prediction of drug responses. Anesthesiology. 2005 Mar; 102(3):494-5.
Anesthesia and the human genome project: the quest for accurate prediction of drug responses.
Kiselyov KI, Shin DM, Wang Y, Pessah IN, Allen PD, Muallem S
Gating of store-operated channels by conformational coupling to ryanodine receptors. Mol Cell. 2000 Aug; 6(2):421-31.
Gating of store-operated channels by conformational coupling to ryanodine receptors.
Perreault CL, Mulieri LA, Alpert NR, Ransil BJ, Allen PD, Morgan JP
Cellular basis of negative inotropic effect of 2,3-butanedione monoxime in human myocardium. Am J Physiol. 1992 Aug; 263(2 Pt 2):H503-10.
Cellular basis of negative inotropic effect of 2,3-butanedione monoxime in human myocardium.
Hwang JJ, Allen PD, Tseng GC, Lam CW, Fananapazir L, Dzau VJ, Liew CC
Microarray gene expression profiles in dilated and hypertrophic cardiomyopathic end-stage heart failure. Physiol Genomics. 2002 Jul 12; 10(1):31-44.
Microarray gene expression profiles in dilated and hypertrophic cardiomyopathic end-stage heart failure.
Avila G, Lee EH, Perez CF, Allen PD, Dirksen RT
FKBP12 binding to RyR1 modulates excitation-contraction coupling in mouse skeletal myotubes. J Biol Chem. 2003 Jun 20; 278(25):22600-8.
FKBP12 binding to RyR1 modulates excitation-contraction coupling in mouse skeletal myotubes.
Amino acids 1-1,680 of ryanodine receptor type 1 hold critical determinants of skeletal type for excitation-contraction coupling. Role of divergence domain D2. J Biol Chem. 2003 Oct 10; 278(41):39644-52.
Amino acids 1-1,680 of ryanodine receptor type 1 hold critical determinants of skeletal type for excitation-contraction coupling. Role of divergence domain D2.
Shtifman A, Paolini C, López JR, Allen PD, Protasi F
Ca2+ influx through alpha1S DHPR may play a role in regulating Ca2+ release from RyR1 in skeletal muscle. Am J Physiol Cell Physiol. 2004 Jan; 286(1):C73-8.
Ca2+ influx through alpha1S DHPR may play a role in regulating Ca2+ release from RyR1 in skeletal muscle.
Expression levels of RyR1 and RyR3 control resting free Ca2+ in skeletal muscle. Am J Physiol Cell Physiol. 2005 Mar; 288(3):C640-9.
Expression levels of RyR1 and RyR3 control resting free Ca2+ in skeletal muscle.
Dyspedic mouse skeletal muscle expresses major elements of the triadic junction but lacks detectable ryanodine receptor protein and function. J Biol Chem. 1997 Mar 14; 272(11):7360-7.
Dyspedic mouse skeletal muscle expresses major elements of the triadic junction but lacks detectable ryanodine receptor protein and function.
Mesnard-Rouiller L, Mercadier JJ, Butler-Browne G, Heimburger M, Logeart D, Allen PD, Samson F
Troponin T mRNA and protein isoforms in the human left ventricle: pattern of expression in failing and control hearts. J Mol Cell Cardiol. 1997 Nov; 29(11):3043-55.
Troponin T mRNA and protein isoforms in the human left ventricle: pattern of expression in failing and control hearts.
Yang HT, Tweedie D, Wang S, Guia A, Vinogradova T, Bogdanov K, Allen PD, Stern MD, Lakatta EG, Boheler KR
The ryanodine receptor modulates the spontaneous beating rate of cardiomyocytes during development. Proc Natl Acad Sci U S A. 2002 Jul 09; 99(14):9225-30.
The ryanodine receptor modulates the spontaneous beating rate of cardiomyocytes during development.
Protasi F, Takekura H, Wang Y, Chen SR, Meissner G, Allen PD, Franzini-Armstrong C
RYR1 and RYR3 have different roles in the assembly of calcium release units of skeletal muscle. Biophys J. 2000 Nov; 79(5):2494-508.
RYR1 and RYR3 have different roles in the assembly of calcium release units of skeletal muscle.
Protasi F, Franzini-Armstrong C, Allen PD
Role of ryanodine receptors in the assembly of calcium release units in skeletal muscle. J Cell Biol. 1998 Feb 23; 140(4):831-42.
Role of ryanodine receptors in the assembly of calcium release units in skeletal muscle.
Rivier F, Alkan O, Flint AF, Muskiewicz K, Allen PD, Leboulch P, Gussoni E
Role of bone marrow cell trafficking in replenishing skeletal muscle SP and MP cell populations. J Cell Sci. 2004 Apr 15; 117(Pt 10):1979-88.
Role of bone marrow cell trafficking in replenishing skeletal muscle SP and MP cell populations.
Felder E, Protasi F, Hirsch R, Franzini-Armstrong C, Allen PD
Morphology and molecular composition of sarcoplasmic reticulum surface junctions in the absence of DHPR and RyR in mouse skeletal muscle. Biophys J. 2002 Jun; 82(6):3144-9.
Morphology and molecular composition of sarcoplasmic reticulum surface junctions in the absence of DHPR and RyR in mouse skeletal muscle.
Effects of dantrolene on myoplasmic free [Ca2+] measured in vivo in patients susceptible to malignant hyperthermia. Anesthesiology. 1992 May; 76(5):711-9.
Effects of dantrolene on myoplasmic free [Ca2+] measured in vivo in patients susceptible to malignant hyperthermia.
Hasenfuss G, Mulieri LA, Leavitt BJ, Allen PD, Holubarsch C, Just H, Alpert NR
Contractile protein function in failing and nonfailing human myocardium. Basic Res Cardiol. 1992; 87 Suppl 1:107-16.
Contractile protein function in failing and nonfailing human myocardium.
Functional defects in six ryanodine receptor isoform-1 (RyR1) mutations associated with malignant hyperthermia and their impact on skeletal excitation-contraction coupling. J Biol Chem. 2003 Jul 11; 278(28):25722-30.
Functional defects in six ryanodine receptor isoform-1 (RyR1) mutations associated with malignant hyperthermia and their impact on skeletal excitation-contraction coupling.
Barrans JD, Allen PD, Stamatiou D, Dzau VJ, Liew CC
Global gene expression profiling of end-stage dilated cardiomyopathy using a human cardiovascular-based cDNA microarray. Am J Pathol. 2002 Jun; 160(6):2035-43.
Global gene expression profiling of end-stage dilated cardiomyopathy using a human cardiovascular-based cDNA microarray.
Allen PD, Schmidt TA, Marsh JD, Kjeldsen K
Na,K-ATPase expression in normal and failing human left ventricle. Basic Res Cardiol. 1992; 87 Suppl 1:87-94.
Na,K-ATPase expression in normal and failing human left ventricle.
Oppenheim RW, Prevette D, Houenou LJ, Pincon-Raymond M, Dimitriadou V, Donevan A, O'Donovan M, Wenner P, Mckemy DD, Allen PD
Neuromuscular development in the avian paralytic mutant crooked neck dwarf (cn/cn): further evidence for the role of neuromuscular activity in motoneuron survival. J Comp Neurol. 1997 May 12; 381(3):353-72.
Neuromuscular development in the avian paralytic mutant crooked neck dwarf (cn/cn): further evidence for the role of neuromuscular activity in motoneuron survival.
Fajloun Z, Kharrat R, Chen L, Lecomte C, Di Luccio E, Bichet D, El Ayeb M, Rochat H, Allen PD, Pessah IN, De Waard M, Sabatier JM
Chemical synthesis and characterization of maurocalcine, a scorpion toxin that activates Ca(2+) release channel/ryanodine receptors. FEBS Lett. 2000 Mar 10; 469(2-3):179-85.
Chemical synthesis and characterization of maurocalcine, a scorpion toxin that activates Ca(2+) release channel/ryanodine receptors.
Lam P, Hui KM, Wang Y, Allen PD, Louis DN, Yuan CJ, Breakefield XO
Dynamics of transgene expression in human glioblastoma cells mediated by herpes simplex virus/adeno-associated virus amplicon vectors. Hum Gene Ther. 2002 Dec 10; 13(18):2147-59.
Dynamics of transgene expression in human glioblastoma cells mediated by herpes simplex virus/adeno-associated virus amplicon vectors.
Eltit JM, Feng W, Lopez JR, Padilla IT, Pessah IN, Molinski TF, Fruen BR, Allen PD, Perez CF
Ablation of skeletal muscle triadin impairs FKBP12/RyR1 channel interactions essential for maintaining resting cytoplasmic Ca2+. J Biol Chem. 2010 Dec 03; 285(49):38453-62.
Ablation of skeletal muscle triadin impairs FKBP12/RyR1 channel interactions essential for maintaining resting cytoplasmic Ca2+.
High-performance ion-exchange chromatography of myosin using a DEAE-5PW column. J Chromatogr. 1989 Jun 30; 491(1):61-8.
High-performance ion-exchange chromatography of myosin using a DEAE-5PW column.
"Noninvasive" testing for malignant hyperthermia susceptibility. Anesthesiology. 2002 Nov; 97(5):1045-6.
"Noninvasive" testing for malignant hyperthermia susceptibility.
Weiss RG, O'Connell KM, Flucher BE, Allen PD, Grabner M, Dirksen RT
Functional analysis of the R1086H malignant hyperthermia mutation in the DHPR reveals an unexpected influence of the III-IV loop on skeletal muscle EC coupling. Am J Physiol Cell Physiol. 2004 Oct; 287(4):C1094-102.
Functional analysis of the R1086H malignant hyperthermia mutation in the DHPR reveals an unexpected influence of the III-IV loop on skeletal muscle EC coupling.
Internal structure and visualization of transmembrane domains of the RyR1 calcium release channel by cryo-EM. Nat Struct Mol Biol. 2005 Jun; 12(6):539-44.
Internal structure and visualization of transmembrane domains of the RyR1 calcium release channel by cryo-EM.
Interplay between intra- and extracellular calcium ions. Mol Cells. 2006 Jun 30; 21(3):315-29.
Interplay between intra- and extracellular calcium ions.
Mercadier JJ, Lompré AM, Duc P, Boheler KR, Fraysse JB, Wisnewsky C, Allen PD, Komajda M, Schwartz K
Altered sarcoplasmic reticulum Ca2(+)-ATPase gene expression in the human ventricle during end-stage heart failure. J Clin Invest. 1990 Jan; 85(1):305-9.
Altered sarcoplasmic reticulum Ca2(+)-ATPase gene expression in the human ventricle during end-stage heart failure.
Yang T, Esteve E, Pessah IN, Molinski TF, Allen PD, López JR
Elevated resting [Ca(2+)](i) in myotubes expressing malignant hyperthermia RyR1 cDNAs is partially restored by modulation of passive calcium leak from the SR. Am J Physiol Cell Physiol. 2007 May; 292(5):C1591-8.
Elevated resting [Ca(2+)](i) in myotubes expressing malignant hyperthermia RyR1 cDNAs is partially restored by modulation of passive calcium leak from the SR.
Bakowska JC, Di Maria MV, Camp SM, Wang Y, Allen PD, Breakefield XO
Targeted transgene integration into transgenic mouse fibroblasts carrying the full-length human AAVS1 locus mediated by HSV/AAV rep(+) hybrid amplicon vector. Gene Ther. 2003 Sep; 10(19):1691-702.
Targeted transgene integration into transgenic mouse fibroblasts carrying the full-length human AAVS1 locus mediated by HSV/AAV rep(+) hybrid amplicon vector.
Ikeda U, Briggs GM, Allen PD, Sen L, Medford RM, Smith TW
Properties of adult rat ventricular cells in long-term culture. Cardioscience. 1990 Sep; 1(3):225-33.
Properties of adult rat ventricular cells in long-term culture.
Moussa CE, Fu Q, Kumar P, Shtifman A, Lopez JR, Allen PD, LaFerla F, Weinberg D, Magrane J, Aprahamian T, Walsh K, Rosen KM, Querfurth HW
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Transgenic expression of beta-APP in fast-twitch skeletal muscle leads to calcium dyshomeostasis and IBM-like pathology. FASEB J. 2006 Oct; 20(12):2165-7.
Transgenic expression of beta-APP in fast-twitch skeletal muscle leads to calcium dyshomeostasis and IBM-like pathology.
Lee EH, Rho SH, Kwon SJ, Eom SH, Allen PD, Kim DH
N-terminal region of FKBP12 is essential for binding to the skeletal ryanodine receptor. J Biol Chem. 2004 Jun 18; 279(25):26481-8.
N-terminal region of FKBP12 is essential for binding to the skeletal ryanodine receptor.
López JR, Mijares A, Rojas B, Linares N, Allen PD, Shtifman A
Altered Ca2+ homeostasis in human uremic skeletal muscle: possible involvement of cADPR in elevation of intracellular resting [Ca2+]. Nephron Physiol. 2005; 100(4):p51-60.
Altered Ca2+ homeostasis in human uremic skeletal muscle: possible involvement of cADPR in elevation of intracellular resting [Ca2+].
Cunha-Neto E, Dzau VJ, Allen PD, Stamatiou D, Benvenutti L, Higuchi ML, Koyama NS, Silva JS, Kalil J, Liew CC
Cardiac gene expression profiling provides evidence for cytokinopathy as a molecular mechanism in Chagas' disease cardiomyopathy. Am J Pathol. 2005 Aug; 167(2):305-13.
Cardiac gene expression profiling provides evidence for cytokinopathy as a molecular mechanism in Chagas' disease cardiomyopathy.
Pike MM, Frazer JC, Dedrick DF, Ingwall JS, Allen PD, Springer CS, Smith TW
23Na and 39K nuclear magnetic resonance studies of perfused rat hearts. Discrimination of intra- and extracellular ions using a shift reagent. Biophys J. 1985 Jul; 48(1):159-73.
23Na and 39K nuclear magnetic resonance studies of perfused rat hearts. Discrimination of intra- and extracellular ions using a shift reagent.
Takahashi T, Allen PD, Lacro RV, Marks AR, Dennis AR, Schoen FJ, Grossman W, Marsh JD, Izumo S
Expression of dihydropyridine receptor (Ca2+ channel) and calsequestrin genes in the myocardium of patients with end-stage heart failure. J Clin Invest. 1992 Sep; 90(3):927-35.
Expression of dihydropyridine receptor (Ca2+ channel) and calsequestrin genes in the myocardium of patients with end-stage heart failure.
Pagani ED, Alousi AA, Grant AM, Older TM, Dziuban SW, Allen PD
Changes in myofibrillar content and Mg-ATPase activity in ventricular tissues from patients with heart failure caused by coronary artery disease, cardiomyopathy, or mitral valve insufficiency. Circ Res. 1988 Aug; 63(2):380-5.
Changes in myofibrillar content and Mg-ATPase activity in ventricular tissues from patients with heart failure caused by coronary artery disease, cardiomyopathy, or mitral valve insufficiency.
Wang Y, Fraefel C, Protasi F, Moore RA, Fessenden JD, Pessah IN, DiFrancesco A, Breakefield X, Allen PD
HSV-1 amplicon vectors are a highly efficient gene delivery system for skeletal muscle myoblasts and myotubes. Am J Physiol Cell Physiol. 2000 Mar; 278(3):C619-26.
HSV-1 amplicon vectors are a highly efficient gene delivery system for skeletal muscle myoblasts and myotubes.
Fessenden JD, Wang Y, Moore RA, Chen SR, Allen PD, Pessah IN
Divergent functional properties of ryanodine receptor types 1 and 3 expressed in a myogenic cell line. Biophys J. 2000 Nov; 79(5):2509-25.
Divergent functional properties of ryanodine receptor types 1 and 3 expressed in a myogenic cell line.
Mulieri LA, Hasenfuss G, Leavitt B, Allen PD, Alpert NR
Altered myocardial force-frequency relation in human heart failure. Circulation. 1992 May; 85(5):1743-50.
Altered myocardial force-frequency relation in human heart failure.
Ward CW, Protasi F, Castillo D, Wang Y, Chen SR, Pessah IN, Allen PD, Schneider MF
Type 1 and type 3 ryanodine receptors generate different Ca(2+) release event activity in both intact and permeabilized myotubes. Biophys J. 2001 Dec; 81(6):3216-30.
Type 1 and type 3 ryanodine receptors generate different Ca(2+) release event activity in both intact and permeabilized myotubes.
Gach MP, Cherednichenko G, Haarmann C, Lopez JR, Beam KG, Pessah IN, Franzini-Armstrong C, Allen PD
Alpha2delta1 dihydropyridine receptor subunit is a critical element for excitation-coupled calcium entry but not for formation of tetrads in skeletal myotubes. Biophys J. 2008 Apr 15; 94(8):3023-34.
Alpha2delta1 dihydropyridine receptor subunit is a critical element for excitation-coupled calcium entry but not for formation of tetrads in skeletal myotubes.
Bodor GS, Oakeley AE, Allen PD, Crimmins DL, Ladenson JH, Anderson PA
Troponin I phosphorylation in the normal and failing adult human heart. Circulation. 1997 Sep 02; 96(5):1495-500.
Troponin I phosphorylation in the normal and failing adult human heart.
Moore RA, Nguyen H, Galceran J, Pessah IN, Allen PD
A transgenic myogenic cell line lacking ryanodine receptor protein for homologous expression studies: reconstitution of Ry1R protein and function. J Cell Biol. 1998 Feb 23; 140(4):843-51.
A transgenic myogenic cell line lacking ryanodine receptor protein for homologous expression studies: reconstitution of Ry1R protein and function.
Troponin T isoform expression in the normal and failing human left ventricle: a correlation with myofibrillar ATPase activity. Basic Res Cardiol. 1992; 87 Suppl 1:117-27.
Troponin T isoform expression in the normal and failing human left ventricle: a correlation with myofibrillar ATPase activity.
Alousi AA, Grant AM, Allen PD, Pagani ED
The Journal of pharmacology and experimental therapeutics
Effects of milrinone on Ca++-sensitivity of myofibrillar Mg-adenosine triphosphatase isolated from normal human and canine hearts. J Pharmacol Exp Ther. 1988 Jul; 246(1):30-7.
Effects of milrinone on Ca++-sensitivity of myofibrillar Mg-adenosine triphosphatase isolated from normal human and canine hearts.
Brooks WW, Bing OH, Blaustein AS, Allen PD
Comparison of contractile state and myosin isozymes of rat right and left ventricular myocardium. J Mol Cell Cardiol. 1987 May; 19(5):433-40.
Comparison of contractile state and myosin isozymes of rat right and left ventricular myocardium.
López JR, Contreras J, Linares N, Allen PD
Hypersensitivity of malignant hyperthermia-susceptible swine skeletal muscle to caffeine is mediated by high resting myoplasmic [Ca2+ ]. Anesthesiology. 2000 Jun; 92(6):1799-806.
Hypersensitivity of malignant hyperthermia-susceptible swine skeletal muscle to caffeine is mediated by high resting myoplasmic [Ca2+ ].
O'Brien JJ, Feng W, Allen PD, Chen SR, Pessah IN, Beam KG
Ca2+ activation of RyR1 is not necessary for the initiation of skeletal-type excitation-contraction coupling. Biophys J. 2002 May; 82(5):2428-35.
Ca2+ activation of RyR1 is not necessary for the initiation of skeletal-type excitation-contraction coupling.
Acute appendicitis in children; a review of 1,165 cases. Ann Surg. 1950 Dec; 132(6):1093-1102.
Acute appendicitis in children; a review of 1,165 cases.
Lee EH, Cherednichenko G, Pessah IN, Allen PD
Functional coupling between TRPC3 and RyR1 regulates the expressions of key triadic proteins. J Biol Chem. 2006 Apr 14; 281(15):10042-8.
Functional coupling between TRPC3 and RyR1 regulates the expressions of key triadic proteins.
Wang Y, Mukherjee S, Fraefel C, Breakefield XO, Allen PD
Herpes simplex virus type 1 amplicon vector-mediated gene transfer to muscle. Hum Gene Ther. 2002 Jan 20; 13(2):261-73.
Herpes simplex virus type 1 amplicon vector-mediated gene transfer to muscle.
Ingwall JS, Kramer MF, Fifer MA, Lorell BH, Shemin R, Grossman W, Allen PD
The creatine kinase system in normal and diseased human myocardium. N Engl J Med. 1985 Oct 24; 313(17):1050-4.
The creatine kinase system in normal and diseased human myocardium.
Cherednichenko G, Hurne AM, Fessenden JD, Lee EH, Allen PD, Beam KG, Pessah IN
Conformational activation of Ca2+ entry by depolarization of skeletal myotubes. Proc Natl Acad Sci U S A. 2004 Nov 02; 101(44):15793-8.
Conformational activation of Ca2+ entry by depolarization of skeletal myotubes.
Hurne AM, O'Brien JJ, Wingrove D, Cherednichenko G, Allen PD, Beam KG, Pessah IN
Ryanodine receptor type 1 (RyR1) mutations C4958S and C4961S reveal excitation-coupled calcium entry (ECCE) is independent of sarcoplasmic reticulum store depletion. J Biol Chem. 2005 Nov 04; 280(44):36994-7004.
Ryanodine receptor type 1 (RyR1) mutations C4958S and C4961S reveal excitation-coupled calcium entry (ECCE) is independent of sarcoplasmic reticulum store depletion.
Structural characterization of the RyR1-FKBP12 interaction. J Mol Biol. 2006 Mar 03; 356(4):917-27.
Structural characterization of the RyR1-FKBP12 interaction.
Boheler KR, Carrier L, de la Bastie D, Allen PD, Komajda M, Mercadier JJ, Schwartz K
Skeletal actin mRNA increases in the human heart during ontogenic development and is the major isoform of control and failing adult hearts. J Clin Invest. 1991 Jul; 88(1):323-30.
Skeletal actin mRNA increases in the human heart during ontogenic development and is the major isoform of control and failing adult hearts.
Phimister AJ, Lango J, Lee EH, Ernst-Russell MA, Takeshima H, Ma J, Allen PD, Pessah IN
Conformation-dependent stability of junctophilin 1 (JP1) and ryanodine receptor type 1 (RyR1) channel complex is mediated by their hyper-reactive thiols. J Biol Chem. 2007 Mar 23; 282(12):8667-77.
Conformation-dependent stability of junctophilin 1 (JP1) and ryanodine receptor type 1 (RyR1) channel complex is mediated by their hyper-reactive thiols.
Fritz N, Morel JL, Jeyakumar LH, Fleischer S, Allen PD, Mironneau J, Macrez N
RyR1-specific requirement for depolarization-induced Ca2+ sparks in urinary bladder smooth muscle. J Cell Sci. 2007 Nov 01; 120(Pt 21):3784-91.
RyR1-specific requirement for depolarization-induced Ca2+ sparks in urinary bladder smooth muscle.
Lee EH, Lopez JR, Li J, Protasi F, Pessah IN, Kim DH, Allen PD
Conformational coupling of DHPR and RyR1 in skeletal myotubes is influenced by long-range allosterism: evidence for a negative regulatory module. Am J Physiol Cell Physiol. 2004 Jan; 286(1):C179-89.
Conformational coupling of DHPR and RyR1 in skeletal myotubes is influenced by long-range allosterism: evidence for a negative regulatory module.
López JR, Linares N, Pessah IN, Allen PD
Enhanced response to caffeine and 4-chloro-m-cresol in malignant hyperthermia-susceptible muscle is related in part to chronically elevated resting [Ca2+]i. Am J Physiol Cell Physiol. 2005 Mar; 288(3):C606-12.
Enhanced response to caffeine and 4-chloro-m-cresol in malignant hyperthermia-susceptible muscle is related in part to chronically elevated resting [Ca2+]i.
Feng W, Tu J, Pouliquin P, Cabrales E, Shen X, Dulhunty A, Worley PF, Allen PD, Pessah IN
Dynamic regulation of ryanodine receptor type 1 (RyR1) channel activity by Homer 1. Cell Calcium. 2008 Mar; 43(3):307-14.
Dynamic regulation of ryanodine receptor type 1 (RyR1) channel activity by Homer 1.
Developmental regulation of cardiac calcium channels and contractile sensitivity to [Ca]o. Am J Physiol. 1989 Jan; 256(1 Pt 2):H179-85.
Developmental regulation of cardiac calcium channels and contractile sensitivity to [Ca]o.
Boncompagni S, Thomas M, Lopez JR, Allen PD, Yuan Q, Kranias EG, Franzini-Armstrong C, Perez CF
Triadin/Junctin double null mouse reveals a differential role for Triadin and Junctin in anchoring CASQ to the jSR and regulating Ca(2+) homeostasis. PLoS One. 2012; 7(7):e39962.
Triadin/Junctin double null mouse reveals a differential role for Triadin and Junctin in anchoring CASQ to the jSR and regulating Ca(2+) homeostasis.
Presbycusis phenotypes form a heterogeneous continuum when ordered by degree and configuration of hearing loss. Hear Res. 2010 Jun 01; 264(1-2):10-20.
Presbycusis phenotypes form a heterogeneous continuum when ordered by degree and configuration of hearing loss.
Perceived exertion associated with breathing hyperoxic mixtures during submaximal work. Med Sci Sports. 1977; 9(2):122-7.
Perceived exertion associated with breathing hyperoxic mixtures during submaximal work.
Feng W, Cherednichenko G, Ward CW, Padilla IT, Cabrales E, Lopez JR, Eltit JM, Allen PD, Pessah IN
Green tea catechins are potent sensitizers of ryanodine receptor type 1 (RyR1). Biochem Pharmacol. 2010 Aug 15; 80(4):512-21.
Green tea catechins are potent sensitizers of ryanodine receptor type 1 (RyR1).
Estrada M, Cárdenas C, Liberona JL, Carrasco MA, Mignery GA, Allen PD, Jaimovich E
Calcium transients in 1B5 myotubes lacking ryanodine receptors are related to inositol trisphosphate receptors. J Biol Chem. 2001 Jun 22; 276(25):22868-74.
Calcium transients in 1B5 myotubes lacking ryanodine receptors are related to inositol trisphosphate receptors.
Leaky "feet" and sudden death. Circ Res. 2002 Aug 09; 91(3):181-2.
Barone V, Bertocchini F, Bottinelli R, Protasi F, Allen PD, Franzini Armstrong C, Reggiani C, Sorrentino V
Contractile impairment and structural alterations of skeletal muscles from knockout mice lacking type 1 and type 3 ryanodine receptors. FEBS Lett. 1998 Jan 30; 422(2):160-4.
Contractile impairment and structural alterations of skeletal muscles from knockout mice lacking type 1 and type 3 ryanodine receptors.
Amino acid residues Gln4020 and Lys4021 of the ryanodine receptor type 1 are required for activation by 4-chloro-m-cresol. J Biol Chem. 2006 Jul 28; 281(30):21022-21031.
Amino acid residues Gln4020 and Lys4021 of the ryanodine receptor type 1 are required for activation by 4-chloro-m-cresol.
Protasi F, Paolini C, Nakai J, Beam KG, Franzini-Armstrong C, Allen PD
Multiple regions of RyR1 mediate functional and structural interactions with alpha(1S)-dihydropyridine receptors in skeletal muscle. Biophys J. 2002 Dec; 83(6):3230-44.
Multiple regions of RyR1 mediate functional and structural interactions with alpha(1S)-dihydropyridine receptors in skeletal muscle.
Bujold M, Caron N, Camiran G, Mukherjee S, Allen PD, Tremblay JP, Wang Y
Autotransplantation in mdx mice of mdx myoblasts genetically corrected by an HSV-1 amplicon vector. Cell Transplant. 2002; 11(8):759-67.
Autotransplantation in mdx mice of mdx myoblasts genetically corrected by an HSV-1 amplicon vector.
Nakai J, Sekiguchi N, Rando TA, Allen PD, Beam KG
Two regions of the ryanodine receptor involved in coupling with L-type Ca2+ channels. J Biol Chem. 1998 May 29; 273(22):13403-6.
Two regions of the ryanodine receptor involved in coupling with L-type Ca2+ channels.