Allen, Paul
eCommons Login: PDA1
first name: Paul
last name: Allen
coauthor of: Breakefield, Xandra
coauthor of: Ingwall, Joanne
coauthor of: Nascimben, Luigino
coauthor of: Vacanti, Charles
coauthor of: Desai, Sukumar
full name: Paul Denney Allen, M.D., Ph.D.
has faculty rank: Full Professor
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latitude: 42.33510370000000
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Person ID: 20466
person in primary position: Professor of Anaesthesia, Emeritus
physical neighbor: Lieberman, Ellice
physical neighbor: Philip, James
physical neighbor: Racowsky, Catherine
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physical neighbor: Vacanti, Charles
similar to: Clapham, David
similar to: Rutkove, Seward
similar to: Goodyear, Laurie
similar to: Brown, Edward
similar to: Hasselgren, Per-Olof
type: Agent
type: Person
selected publications: Authorship 656139
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Authorship 102058
type: Authorship
author rank in publication: 4
linked author: Allen, Paul
linked information resource: Contractile protein function in failing and nonfailing human myocardium.

Expression of functional Na,K-ATPase isozymes in normal human cardiac biopsies.
PubMed Identifier: 11355000
author list: Lelievr LG, Crambert G, Allen PD
published in: Cellular and molecular biology (Noisy-le-Grand, France)
information resource reference: Expression of functional Na,K-ATPase isozymes in normal human cardiac biopsies. Cell Mol Biol (Noisy-le-grand). 2001 Mar; 47(2):265-71.
journal title abbreviation: Cell Mol Biol (Noisy-le-grand)
publication date: 2001-03-01T00:00:00
year: 2001
type: Academic Article
type: Article
type: Document
type: Information Resource

RyR1 and RyR3 isoforms provide distinct intracellular Ca2+ signals in HEK 293 cells.
PubMed Identifier: 12045220
author list: Rossi D, Simeoni I, Micheli M, Bootman M, Lipp P, Allen PD, Sorrentino V
published in: Journal of cell science
information resource reference: RyR1 and RyR3 isoforms provide distinct intracellular Ca2+ signals in HEK 293 cells. J Cell Sci. 2002 06 15; 115(Pt 12):2497-504.
journal title abbreviation: J Cell Sci
publication date: 2002-06-15T00:00:00
year: 2002
type: Academic Article
type: Article
type: Document
type: Information Resource

EU 4093 decreases intracellular [Ca2+] in skeletal muscle fibers from control and malignant hyperthermia-susceptible swine.
PubMed Identifier: 1729917
author list: Allen PD, López JR, Sánchez V, Ryan JF, Sreter FA
published in: Anesthesiology
information resource reference: EU 4093 decreases intracellular [Ca2+] in skeletal muscle fibers from control and malignant hyperthermia-susceptible swine. Anesthesiology. 1992 Jan; 76(1):132-8.
journal title abbreviation: Anesthesiology
publication date: 1992-01-01T00:00:00
year: 1992
type: Academic Article
type: Article
type: Document
type: Information Resource

Physostigmine: effectiveness as an antagonist of respiratory depression and psychomotor effects caused by morphine or diazepam.
PubMed Identifier: 6437286
author list: Bourke DL, Rosenberg M, Allen PD
published in: Anesthesiology
information resource reference: Physostigmine: effectiveness as an antagonist of respiratory depression and psychomotor effects caused by morphine or diazepam. Anesthesiology. 1984 Nov; 61(5):523-8.
journal title abbreviation: Anesthesiology
publication date: 1984-11-01T00:00:00
year: 1984
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 102340
type: Authorship
author rank in publication: 1
linked author: Allen, Paul
linked information resource: Sarcoplasmic reticulum calcium uptake in cryostat sections of skeletal muscle from malignant hyperthermia patients and controls.

Calcium dyshomeostasis in beta-amyloid and tau-bearing skeletal myotubes.
PubMed Identifier: 15385569
author list: Christensen RA, Shtifman A, Allen PD, Lopez JR, Querfurth HW
published in: The Journal of biological chemistry
information resource reference: Calcium dyshomeostasis in beta-amyloid and tau-bearing skeletal myotubes. J Biol Chem. 2004 Dec 17; 279(51):53524-32.
journal title abbreviation: J Biol Chem
publication date: 2004-09-22T00:00:00
year: 2004
type: Academic Article
type: Article
type: Document
type: Information Resource

[Ca2+]i in muscles of malignant hyperthermia susceptible pigs determined in vivo with Ca2+ selective microelectrodes.
PubMed Identifier: 3951486
author list: Lopez JR, Alamo LA, Jones DE, Papp L, Allen PD, Gergely J, Sréter FA
published in: Muscle & nerve
information resource reference: [Ca2+]i in muscles of malignant hyperthermia susceptible pigs determined in vivo with Ca2+ selective microelectrodes. Muscle Nerve. 1986 Jan; 9(1):85-6.
journal title abbreviation: Muscle Nerve
publication date: 1986-01-01T00:00:00
year: 1986
type: Academic Article
type: Article
type: Document
type: Information Resource

Modulation of cardiovascular function and platelet survival by endogenous prostacyclin released during surgery.
PubMed Identifier: 6340233
author list: Krausz MM, Utsunomiya T, McIrvine AJ, Allen PD, Levine L, Mannick JA, Shepro D, Hechtman HB
published in: Surgery
information resource reference: Modulation of cardiovascular function and platelet survival by endogenous prostacyclin released during surgery. Surgery. 1983 Apr; 93(4):554-9.
journal title abbreviation: Surgery
publication date: 1983-04-01T00:00:00
year: 1983
type: Academic Article
type: Article
type: Document
type: Information Resource

Molecular basis of human cardiac troponin T isoforms expressed in the developing, adult, and failing heart.
PubMed Identifier: 7534662
author list: Anderson PA, Greig A, Mark TM, Malouf NN, Oakeley AE, Ungerleider RM, Allen PD, Kay BK
published in: Circulation research
information resource reference: Molecular basis of human cardiac troponin T isoforms expressed in the developing, adult, and failing heart. Circ Res. 1995 Apr; 76(4):681-6.
journal title abbreviation: Circ Res
publication date: 1995-04-01T00:00:00
year: 1995
type: Academic Article
type: Article
type: Document
type: Information Resource

The gene encoding endothelial nitric oxide synthase, Nos3, maps to rat chromosome 4.
PubMed Identifier: 8563182
author list: Hübner N, Kreutz R, Rubattu S, Lee YA, Ganten D, Allen PD, Lindpaintner K
published in: Mammalian genome : official journal of the International Mammalian Genome Society
information resource reference: The gene encoding endothelial nitric oxide synthase, Nos3, maps to rat chromosome 4. Mamm Genome. 1995 Oct; 6(10):758-9.
journal title abbreviation: Mamm Genome
publication date: 1995-10-01T00:00:00
year: 1995
type: Academic Article
type: Article
type: Document
type: Information Resource

Expression of A-, B-, and C-type natriuretic peptide genes in failing and developing human ventricles. Correlation with expression of the Ca(2+)-ATPase gene.
PubMed Identifier: 1535030
author list: Takahashi T, Allen PD, Izumo S
published in: Circulation research
information resource reference: Expression of A-, B-, and C-type natriuretic peptide genes in failing and developing human ventricles. Correlation with expression of the Ca(2+)-ATPase gene. Circ Res. 1992 Jul; 71(1):9-17.
journal title abbreviation: Circ Res
publication date: 1992-07-01T00:00:00
year: 1992
type: Academic Article
type: Article
type: Document
type: Information Resource

Reorganized stores and impaired calcium handling in skeletal muscle of mice lacking calsequestrin-1.
PubMed Identifier: 17627988
author list: Paolini C, Quarta M, Nori A, Boncompagni S, Canato M, Volpe P, Allen PD, Reggiani C, Protasi F
published in: The Journal of physiology
information resource reference: Reorganized stores and impaired calcium handling in skeletal muscle of mice lacking calsequestrin-1. J Physiol. 2007 Sep 01; 583(Pt 2):767-84.
journal title abbreviation: J Physiol
publication date: 2007-07-12T00:00:00
year: 2007
type: Academic Article
type: Article
type: Document
type: Information Resource

Homer regulates gain of ryanodine receptor type 1 channel complex.
PubMed Identifier: 12223488
author list: Feng W, Tu J, Yang T, Vernon PS, Allen PD, Worley PF, Pessah IN
published in: The Journal of biological chemistry
information resource reference: Homer regulates gain of ryanodine receptor type 1 channel complex. J Biol Chem. 2002 Nov 22; 277(47):44722-30.
journal title abbreviation: J Biol Chem
publication date: 2002-09-09T00:00:00
year: 2002
type: Academic Article
type: Article
type: Document
type: Information Resource

The calmodulin binding region of the skeletal ryanodine receptor acts as a self-modulatory domain.
PubMed Identifier: 14706290
author list: Zhu X, Ghanta J, Walker JW, Allen PD, Valdivia HH
published in: Cell calcium
information resource reference: The calmodulin binding region of the skeletal ryanodine receptor acts as a self-modulatory domain. Cell Calcium. 2004 Feb; 35(2):165-77.
journal title abbreviation: Cell Calcium
publication date: 2004-02-01T00:00:00
year: 2004
type: Academic Article
type: Article
type: Document
type: Information Resource

Troponin T isoform expression in humans. A comparison among normal and failing adult heart, fetal heart, and adult and fetal skeletal muscle.
PubMed Identifier: 1934353
author list: Anderson PA, Malouf NN, Oakeley AE, Pagani ED, Allen PD
published in: Circulation research
information resource reference: Troponin T isoform expression in humans. A comparison among normal and failing adult heart, fetal heart, and adult and fetal skeletal muscle. Circ Res. 1991 Nov; 69(5):1226-33.
journal title abbreviation: Circ Res
publication date: 1991-11-01T00:00:00
year: 1991
type: Academic Article
type: Article
type: Document
type: Information Resource

Distribution and function of human ventricular beta adrenergic receptors in congestive heart failure.
PubMed Identifier: 2552129
author list: Denniss AR, Colucci WS, Allen PD, Marsh JD
published in: Journal of molecular and cellular cardiology
information resource reference: Distribution and function of human ventricular beta adrenergic receptors in congestive heart failure. J Mol Cell Cardiol. 1989 Jul; 21(7):651-60.
journal title abbreviation: J Mol Cell Cardiol
publication date: 1989-07-01T00:00:00
year: 1989
type: Academic Article
type: Article
type: Document
type: Information Resource

Humoral blockade on lethal pulmonary embolism in the awake dog.
PubMed Identifier: 4399269
author list: Jacobsen DC, Soden KJ, Allen PD, Daicoff GR
published in: Surgical forum
information resource reference: Humoral blockade on lethal pulmonary embolism in the awake dog. Surg Forum. 1971; 22:209-11.
journal title abbreviation: Surg Forum
publication date: 1971-01-01T00:00:00
year: 1971
type: Academic Article
type: Article
type: Document
type: Information Resource

Kinetic studies of Ca2+ release from sarcoplasmic reticulum of normal and malignant hyperthermia susceptible pig muscles.
PubMed Identifier: 6087905
author list: Kim DH, Sreter FA, Ohnishi ST, Ryan JF, Roberts J, Allen PD, Meszaros LG, Antoniu B, Ikemoto N
published in: Biochimica et biophysica acta
information resource reference: Kinetic studies of Ca2+ release from sarcoplasmic reticulum of normal and malignant hyperthermia susceptible pig muscles. Biochim Biophys Acta. 1984 Sep 05; 775(3):320-7.
journal title abbreviation: Biochim Biophys Acta
publication date: 1984-09-05T00:00:00
year: 1984
type: Academic Article
type: Article
type: Document
type: Information Resource

Triadins modulate intracellular Ca(2+) homeostasis but are not essential for excitation-contraction coupling in skeletal muscle.
PubMed Identifier: 17981799
author list: Shen X, Franzini-Armstrong C, Lopez JR, Jones LR, Kobayashi YM, Wang Y, Kerrick WG, Caswell AH, Potter JD, Miller T, Allen PD, Perez CF
published in: The Journal of biological chemistry
information resource reference: Triadins modulate intracellular Ca(2+) homeostasis but are not essential for excitation-contraction coupling in skeletal muscle. J Biol Chem. 2007 Dec 28; 282(52):37864-74.
journal title abbreviation: J Biol Chem
publication date: 2007-11-02T00:00:00
year: 2007
type: Academic Article
type: Article
type: Document
type: Information Resource

Homo-dimerization of RyR1 C-terminus via charged residues in random coils or in an alpha-helix.
PubMed Identifier: 18059135
author list: Lee EH, Allen PD
published in: Experimental & molecular medicine
information resource reference: Homo-dimerization of RyR1 C-terminus via charged residues in random coils or in an alpha-helix. Exp Mol Med. 2007 Oct 31; 39(5):594-602.
journal title abbreviation: Exp Mol Med
publication date: 2007-10-31T00:00:00
year: 2007
type: Academic Article
type: Article
type: Document
type: Information Resource

Coordinated movement of cytoplasmic and transmembrane domains of RyR1 upon gating.
PubMed Identifier: 19402748
author list: Samsó M, Feng W, Pessah IN, Allen PD
published in: PLoS biology
information resource reference: Coordinated movement of cytoplasmic and transmembrane domains of RyR1 upon gating. PLoS Biol. 2009 Apr 14; 7(4):e85.
journal title abbreviation: PLoS Biol
publication date: 2009-04-14T00:00:00
year: 2009
type: Academic Article
type: Article
type: Document
type: Information Resource

Contractility effects of local anesthetics in the presence of sodium channel blockade.
PubMed Identifier: 2562153
author list: Desai SP, Marsh JD, Allen PD
published in: Regional anesthesia
information resource reference: Contractility effects of local anesthetics in the presence of sodium channel blockade. Reg Anesth. 1989 Mar-Apr; 14(2):58-62.
journal title abbreviation: Reg Anesth
publication date: 1989-03-01T00:00:00
year: 1989
type: Academic Article
type: Article
type: Document
type: Information Resource

A malignant hyperthermia-inducing mutation in RYR1 (R163C): consequent alterations in the functional properties of DHPR channels.
PubMed Identifier: 20479108
author list: Bannister RA, Estève E, Eltit JM, Pessah IN, Allen PD, López JR, Beam KG
published in: The Journal of general physiology
information resource reference: A malignant hyperthermia-inducing mutation in RYR1 (R163C): consequent alterations in the functional properties of DHPR channels. J Gen Physiol. 2010 Jun; 135(6):629-40.
journal title abbreviation: J Gen Physiol
publication date: 2010-05-17T00:00:00
year: 2010
type: Academic Article
type: Article
type: Document
type: Information Resource

Frog alpha- and beta-ryanodine receptors provide distinct intracellular Ca2+ signals in a myogenic cell line.
PubMed Identifier: 20634947
author list: Kashiyama T, Murayama T, Suzuki E, Allen PD, Ogawa Y
published in: PloS one
information resource reference: Frog alpha- and beta-ryanodine receptors provide distinct intracellular Ca2+ signals in a myogenic cell line. PLoS One. 2010 Jul 12; 5(7):e11526.
journal title abbreviation: PLoS One
publication date: 2010-07-12T00:00:00
year: 2010
type: Academic Article
type: Article
type: Document
type: Information Resource

RyR1/RyR3 chimeras reveal that multiple domains of RyR1 are involved in skeletal-type E-C coupling.
PubMed Identifier: 12668474
author list: Perez CF, Voss A, Pessah IN, Allen PD
published in: Biophysical journal
information resource reference: RyR1/RyR3 chimeras reveal that multiple domains of RyR1 are involved in skeletal-type E-C coupling. Biophys J. 2003 Apr; 84(4):2655-63.
journal title abbreviation: Biophys J
publication date: 2003-04-01T00:00:00
year: 2003
type: Academic Article
type: Article
type: Document
type: Information Resource

All three ryanodine receptor isoforms generate rapid cooling responses in muscle cells.
PubMed Identifier: 14592807
author list: Protasi F, Shtifman A, Julian FJ, Allen PD
published in: American journal of physiology. Cell physiology
information resource reference: All three ryanodine receptor isoforms generate rapid cooling responses in muscle cells. Am J Physiol Cell Physiol. 2004 Mar; 286(3):C662-70.
journal title abbreviation: Am J Physiol Cell Physiol
publication date: 2003-10-30T00:00:00
year: 2003
type: Academic Article
type: Article
type: Document
type: Information Resource

Genomics, proteomics and bioinformatics of human heart failure.
PubMed Identifier: 14620738
author list: Dos Remedios CG, Liew CC, Allen PD, Winslow RL, Van Eyk JE, Dunn MJ
published in: Journal of muscle research and cell motility
information resource reference: Genomics, proteomics and bioinformatics of human heart failure. J Muscle Res Cell Motil. 2003; 24(4-6):251-60.
journal title abbreviation: J Muscle Res Cell Motil
publication date: 2003-01-01T00:00:00
year: 2003
type: Academic Article
type: Article
type: Document
type: Information Resource

Occurrence of atypical Ca2+ transients in triadin-binding deficient-RYR1 mutants.
PubMed Identifier: 17092484
author list: Lee EH, Song DW, Lee JM, Meissner G, Allen PD, Kim DH
published in: Biochemical and biophysical research communications
information resource reference: Occurrence of atypical Ca2+ transients in triadin-binding deficient-RYR1 mutants. Biochem Biophys Res Commun. 2006 Dec 29; 351(4):909-14.
journal title abbreviation: Biochem Biophys Res Commun
publication date: 2006-11-07T00:00:00
year: 2006
type: Academic Article
type: Article
type: Document
type: Information Resource

Abnormal intracellular calcium handling, a major cause of systolic and diastolic dysfunction in ventricular myocardium from patients with heart failure.
PubMed Identifier: 2153479
author list: Morgan JP, Erny RE, Allen PD, Grossman W, Gwathmey JK
published in: Circulation
information resource reference: Abnormal intracellular calcium handling, a major cause of systolic and diastolic dysfunction in ventricular myocardium from patients with heart failure. Circulation. 1990 Feb; 81(2 Suppl):III21-32.
journal title abbreviation: Circulation
publication date: 1990-02-01T00:00:00
year: 1990
type: Academic Article
type: Article
type: Document
type: Information Resource

A malignant hyperthermia-inducing mutation in RYR1 (R163C): alterations in Ca2+ entry, release, and retrograde signaling to the DHPR.
PubMed Identifier: 20479110
author list: Estève E, Eltit JM, Bannister RA, Liu K, Pessah IN, Beam KG, Allen PD, López JR
published in: The Journal of general physiology
information resource reference: A malignant hyperthermia-inducing mutation in RYR1 (R163C): alterations in Ca2+ entry, release, and retrograde signaling to the DHPR. J Gen Physiol. 2010 Jun; 135(6):619-28.
journal title abbreviation: J Gen Physiol
publication date: 2010-05-17T00:00:00
year: 2010
type: Academic Article
type: Article
type: Document
type: Information Resource

Three-dimensional localization of the a and ß subunits and of the II-III loop in the skeletal muscle L-type Ca2+ channel.
PubMed Identifier: 23118233
author list: Szpyt J, Lorenzon N, Perez CF, Norris E, Allen PD, Beam KG, Samsó M
published in: The Journal of biological chemistry
information resource reference: Three-dimensional localization of the a and ß subunits and of the II-III loop in the skeletal muscle L-type Ca2+ channel. J Biol Chem. 2012 Dec 21; 287(52):43853-61.
journal title abbreviation: J Biol Chem
publication date: 2012-11-01T00:00:00
year: 2012
type: Academic Article
type: Article
type: Document
type: Information Resource

Myoplasmic free [Ca2+] during a malignant hyperthermia episode in swine.
PubMed Identifier: 3340102
author list: López JR, Allen PD, Alamo L, Jones D, Sreter FA
published in: Muscle & nerve
information resource reference: Myoplasmic free [Ca2+] during a malignant hyperthermia episode in swine. Muscle Nerve. 1988 Jan; 11(1):82-8.
journal title abbreviation: Muscle Nerve
publication date: 1988-01-01T00:00:00
year: 1988
type: Academic Article
type: Article
type: Document
type: Information Resource

Is mammography painful? A multicenter patient survey.
PubMed Identifier: 3341852
author list: Stomper PC, Kopans DB, Sadowsky NL, Sonnenfeld MR, Swann CA, Gelman RS, Meyer JE, Jochelson MS, Hunt MS, Allen PD
published in: Archives of internal medicine
information resource reference: Is mammography painful? A multicenter patient survey. Arch Intern Med. 1988 Mar; 148(3):521-4.
journal title abbreviation: Arch Intern Med
publication date: 1988-03-01T00:00:00
year: 1988
type: Academic Article
type: Article
type: Document
type: Information Resource

Dextroamphetamine with morphine: respiratory effects.
PubMed Identifier: 6404951
author list: Bourke DL, Allen PD, Rosenberg M, Mendes RW, Karabelas AN
published in: Journal of clinical pharmacology
information resource reference: Dextroamphetamine with morphine: respiratory effects. J Clin Pharmacol. 1983 Jan; 23(1):65-70.
journal title abbreviation: J Clin Pharmacol
publication date: 1983-01-01T00:00:00
year: 1983
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 115626
type: Authorship
author rank in publication: 5
linked author: Allen, Paul
linked information resource: Ryanodine receptor type 1 (RyR1) mutations C4958S and C4961S reveal excitation-coupled calcium entry (ECCE) is independent of sarcoplasmic reticulum store depletion.

Authorship 112016
type: Authorship
author rank in publication: 5
linked author: Allen, Paul
linked information resource: A transgenic myogenic cell line lacking ryanodine receptor protein for homologous expression studies: reconstitution of Ry1R protein and function.

The effects of extracellular magnesium on myoplasmic [Ca2+] in malignant hyperthermia susceptible swine.
PubMed Identifier: 2360720
author list: Lopez JR, Sanchez V, Lopez I, Ryan JF, Mendoza M, Sreter FA, Allen PD
published in: Anesthesiology
information resource reference: The effects of extracellular magnesium on myoplasmic [Ca2+] in malignant hyperthermia susceptible swine. Anesthesiology. 1990 Jul; 73(1):109-17.
journal title abbreviation: Anesthesiology
publication date: 1990-07-01T00:00:00
year: 1990
type: Academic Article
type: Article
type: Document
type: Information Resource

Sarcoplasmic reticulum calcium uptake in cryostat sections of skeletal muscle from malignant hyperthermia patients and controls.
PubMed Identifier: 3724793
author list: Allen PD, Ryan JF, Jones DE, Mabuchi K, Virga A, Roberts J, Sreter F
published in: Muscle & nerve
information resource reference: Sarcoplasmic reticulum calcium uptake in cryostat sections of skeletal muscle from malignant hyperthermia patients and controls. Muscle Nerve. 1986 Jun; 9(5):474-5.
journal title abbreviation: Muscle Nerve
publication date: 1986-06-01T00:00:00
year: 1986
type: Academic Article
type: Article
type: Document
type: Information Resource

Triadin, not essential, but useful.
PubMed Identifier: 19567750
author list: Allen PD
published in: The Journal of physiology
information resource reference: Triadin, not essential, but useful. J Physiol. 2009 Jul 01; 587(Pt 13):3123-4.
journal title abbreviation: J Physiol
publication date: 2009-07-01T00:00:00
year: 2009
type: Academic Article
type: Article
type: Document
type: Information Resource

Heart and skeletal muscle are targets of dengue virus infection.
PubMed Identifier: 20032806
author list: Salgado DM, Eltit JM, Mansfield K, Panqueba C, Castro D, Vega MR, Xhaja K, Schmidt D, Martin KJ, Allen PD, Rodriguez JA, Dinsmore JH, López JR, Bosch I
published in: The Pediatric infectious disease journal
information resource reference: Heart and skeletal muscle are targets of dengue virus infection. Pediatr Infect Dis J. 2010 Mar; 29(3):238-42.
journal title abbreviation: Pediatr Infect Dis J
publication date: 2010-03-01T00:00:00
year: 2010
type: Academic Article
type: Article
type: Document
type: Information Resource

Ablation of triadin causes loss of cardiac Ca2+ release units, impaired excitation-contraction coupling, and cardiac arrhythmias.
PubMed Identifier: 19383796
author list: Chopra N, Yang T, Asghari P, Moore ED, Huke S, Akin B, Cattolica RA, Perez CF, Hlaing T, Knollmann-Ritschel BE, Jones LR, Pessah IN, Allen PD, Franzini-Armstrong C, Knollmann BC
published in: Proceedings of the National Academy of Sciences of the United States of America
information resource reference: Ablation of triadin causes loss of cardiac Ca2+ release units, impaired excitation-contraction coupling, and cardiac arrhythmias. Proc Natl Acad Sci U S A. 2009 May 05; 106(18):7636-41.
journal title abbreviation: Proc Natl Acad Sci U S A
publication date: 2009-04-21T00:00:00
year: 2009
type: Academic Article
type: Article
type: Document
type: Information Resource

RyR1-mediated Ca2+ leak and Ca2+ entry determine resting intracellular Ca2+ in skeletal myotubes.
PubMed Identifier: 20207743
author list: Eltit JM, Yang T, Li H, Molinski TF, Pessah IN, Allen PD, Lopez JR
published in: The Journal of biological chemistry
information resource reference: RyR1-mediated Ca2+ leak and Ca2+ entry determine resting intracellular Ca2+ in skeletal myotubes. J Biol Chem. 2010 Apr 30; 285(18):13781-7.
journal title abbreviation: J Biol Chem
publication date: 2010-03-05T00:00:00
year: 2010
type: Academic Article
type: Article
type: Document
type: Information Resource

Enhanced excitation-coupled calcium entry in myotubes is associated with expression of RyR1 malignant hyperthermia mutations.
PubMed Identifier: 17942409
author list: Yang T, Allen PD, Pessah IN, Lopez JR
published in: The Journal of biological chemistry
information resource reference: Enhanced excitation-coupled calcium entry in myotubes is associated with expression of RyR1 malignant hyperthermia mutations. J Biol Chem. 2007 Dec 28; 282(52):37471-8.
journal title abbreviation: J Biol Chem
publication date: 2007-10-16T00:00:00
year: 2007
type: Academic Article
type: Article
type: Document
type: Information Resource

Enhanced excitation-coupled calcium entry in myotubes expressing malignant hyperthermia mutation R163C is attenuated by dantrolene.
PubMed Identifier: 18171728
author list: Cherednichenko G, Ward CW, Feng W, Cabrales E, Michaelson L, Samso M, López JR, Allen PD, Pessah IN
published in: Molecular pharmacology
information resource reference: Enhanced excitation-coupled calcium entry in myotubes expressing malignant hyperthermia mutation R163C is attenuated by dantrolene. Mol Pharmacol. 2008 Apr; 73(4):1203-12.
journal title abbreviation: Mol Pharmacol
publication date: 2008-01-02T00:00:00
year: 2008
type: Academic Article
type: Article
type: Document
type: Information Resource

Maintenance of cardiodynamics with aspirin during abdominal aortic aneurysmectomy (AAA).
PubMed Identifier: 6117260
author list: Utsunomiya T, Krausz MM, Dunham B, Mannick JA, Allen PD, Shepro D, Hechtman HB
published in: Annals of surgery
information resource reference: Maintenance of cardiodynamics with aspirin during abdominal aortic aneurysmectomy (AAA). Ann Surg. 1981 Nov; 194(5):602-8.
journal title abbreviation: Ann Surg
publication date: 1981-11-01T00:00:00
year: 1981
type: Academic Article
type: Article
type: Document
type: Information Resource

Enhanced dihydropyridine receptor channel activity in the presence of ryanodine receptor.
PubMed Identifier: 8598910
author list: Nakai J, Dirksen RT, Nguyen HT, Pessah IN, Beam KG, Allen PD
published in: Nature
information resource reference: Enhanced dihydropyridine receptor channel activity in the presence of ryanodine receptor. Nature. 1996 Mar 07; 380(6569):72-5.
journal title abbreviation: Nature
publication date: 1996-03-07T00:00:00
year: 1996
type: Academic Article
type: Article
type: Document
type: Information Resource

Inhibition of the creatine kinase reaction decreases the contractile reserve of isolated rat hearts.
PubMed Identifier: 7573498
author list: Hamman BL, Bittl JA, Jacobus WE, Allen PD, Spencer RS, Tian R, Ingwall JS
published in: The American journal of physiology
information resource reference: Inhibition of the creatine kinase reaction decreases the contractile reserve of isolated rat hearts. Am J Physiol. 1995 Sep; 269(3 Pt 2):H1030-6.
journal title abbreviation: Am J Physiol
publication date: 1995-09-01T00:00:00
year: 1995
type: Academic Article
type: Article
type: Document
type: Information Resource

The relationship between temperature and oxygen uptake of contracting skeletal muscle.
PubMed Identifier: 4826689
author list: Barclay JK, Allen PD, Stainsby WN
published in: Medicine and science in sports
information resource reference: The relationship between temperature and oxygen uptake of contracting skeletal muscle. Med Sci Sports. 1974; 6(1):33-7.
journal title abbreviation: Med Sci Sports
publication date: 1974-01-01T00:00:00
year: 1974
type: Academic Article
type: Article
type: Document
type: Information Resource

Modulation by the thyroid state of intracellular calcium and contractility in ferret ventricular muscle.
PubMed Identifier: 3197273
author list: MacKinnon R, Gwathmey JK, Allen PD, Briggs GM, Morgan JP
published in: Circulation research
information resource reference: Modulation by the thyroid state of intracellular calcium and contractility in ferret ventricular muscle. Circ Res. 1988 Dec; 63(6):1080-9.
journal title abbreviation: Circ Res
publication date: 1988-12-01T00:00:00
year: 1988
type: Academic Article
type: Article
type: Document
type: Information Resource

Epidural morphine provides postoperative pain relief in peripheral vascular and orthopedic surgical patients: a dose-response study.
PubMed Identifier: 3942304
author list: Allen PD, Walman T, Concepcion M, Sheskey M, Patterson MK, Cullen D, Covino BG
published in: Anesthesia and analgesia
information resource reference: Epidural morphine provides postoperative pain relief in peripheral vascular and orthopedic surgical patients: a dose-response study. Anesth Analg. 1986 Feb; 65(2):165-70.
journal title abbreviation: Anesth Analg
publication date: 1986-02-01T00:00:00
year: 1986
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 11432
type: Authorship
author rank in publication: 7
linked author: Allen, Paul
linked information resource: The effects of extracellular magnesium on myoplasmic [Ca2+] in malignant hyperthermia susceptible swine.

Authorship 13537
type: Authorship
author rank in publication: 1
linked author: Allen, Paul
linked information resource: Epidural morphine provides postoperative pain relief in peripheral vascular and orthopedic surgical patients: a dose-response study.

Authorship 131803
type: Authorship
author rank in publication: 7
linked author: Allen, Paul
linked information resource: Expression of ryanodine receptor RyR3 produces Ca2+ sparks in dyspedic myotubes.

https://connects.catalyst.harvard.edu/Profiles/profile/1144951
PubMed Identifier: 8222079
author list: Glass MG, Fuleihan F, Liao R, Lincoff AM, Chapados R, Hamlin R, Apstein CS, Allen PD, Ingwall JS, Hajjar RJ
published in: Circulation research
information resource reference: Differences in cardioprotective efficacy of adrenergic receptor antagonists and Ca2+ channel antagonists in an animal model of dilated cardiomyopathy. Effects on gross morphology, global cardiac function, and twitch force. Circ Res. 1993 Dec; 73(6):1077-89.
journal title abbreviation: Circ Res
publication date: 1993-12-01T00:00:00
year: 1993
type: Academic Article
type: Article
type: Document
type: Information Resource
label: Differences in cardioprotective efficacy of adrenergic receptor antagonists and Ca2+ channel antagonists in an animal model of dilated cardiomyopathy. Effects on gross morphology, global cardiac function, and twitch force.

https://connects.catalyst.harvard.edu/Profiles/profile/1145083
PubMed Identifier: 8380532
author list: Schmidt TA, Allen PD, Colucci WS, Marsh JD, Kjeldsen K
published in: The American journal of cardiology
information resource reference: No adaptation to digitalization as evaluated by digitalis receptor (Na,K-ATPase) quantification in explanted hearts from donors without heart disease and from digitalized recipients with end-stage heart failure. Am J Cardiol. 1993 Jan 01; 71(1):110-4.
journal title abbreviation: Am J Cardiol
publication date: 1993-01-01T00:00:00
year: 1993
type: Academic Article
type: Article
type: Document
type: Information Resource
label: No adaptation to digitalization as evaluated by digitalis receptor (Na,K-ATPase) quantification in explanted hearts from donors without heart disease and from digitalized recipients with end-stage heart failure.

Determinants of cardiovascular stability during abdominal aortic aneurysmectomy (AAA).
PubMed Identifier: 6365002
author list: Huval WV, Lelcuk S, Allen PD, Mannick JA, Shepro D, Hechtman HB
published in: Annals of surgery
information resource reference: Determinants of cardiovascular stability during abdominal aortic aneurysmectomy (AAA). Ann Surg. 1984 Feb; 199(2):216-22.
journal title abbreviation: Ann Surg
publication date: 1984-02-01T00:00:00
year: 1984
type: Academic Article
type: Article
type: Document
type: Information Resource

Negative inotropic and relaxant effects of cocaine on myopathic human ventricular myocardium and epicardial coronary arteries in vitro.
PubMed Identifier: 8472278
author list: Perreault CL, Hague NL, Morgan KG, Allen PD, Morgan JP
published in: Cardiovascular research
information resource reference: Negative inotropic and relaxant effects of cocaine on myopathic human ventricular myocardium and epicardial coronary arteries in vitro. Cardiovasc Res. 1993 Feb; 27(2):262-8.
journal title abbreviation: Cardiovasc Res
publication date: 1993-02-01T00:00:00
year: 1993
type: Academic Article
type: Article
type: Document
type: Information Resource

Bidirectional signaling between calcium channels of skeletal muscle requires multiple direct and indirect interactions.
PubMed Identifier: 17172444
author list: Sheridan DC, Takekura H, Franzini-Armstrong C, Beam KG, Allen PD, Perez CF
published in: Proceedings of the National Academy of Sciences of the United States of America
information resource reference: Bidirectional signaling between calcium channels of skeletal muscle requires multiple direct and indirect interactions. Proc Natl Acad Sci U S A. 2006 Dec 26; 103(52):19760-5.
journal title abbreviation: Proc Natl Acad Sci U S A
publication date: 2006-12-15T00:00:00
year: 2006
type: Academic Article
type: Article
type: Document
type: Information Resource

Myoplasmic calcium changes precede metabolic and clinical signs of porcine malignant hyperthermia.
PubMed Identifier: 7978379
author list: Ryan JF, Lopez JR, Sanchez VB, Sréter FA, Allen PD
published in: Anesthesia and analgesia
information resource reference: Myoplasmic calcium changes precede metabolic and clinical signs of porcine malignant hyperthermia. Anesth Analg. 1994 Nov; 79(5):1007-11.
journal title abbreviation: Anesth Analg
publication date: 1994-11-01T00:00:00
year: 1994
type: Academic Article
type: Article
type: Document
type: Information Resource

Influence of isoproterenol and ouabain on excitation-contraction coupling, cross-bridge function, and energetics in failing human myocardium.
PubMed Identifier: 8989123
author list: Hasenfuss G, Mulieri LA, Allen PD, Just H, Alpert NR
published in: Circulation
information resource reference: Influence of isoproterenol and ouabain on excitation-contraction coupling, cross-bridge function, and energetics in failing human myocardium. Circulation. 1996 Dec 15; 94(12):3155-60.
journal title abbreviation: Circulation
publication date: 1996-12-15T00:00:00
year: 1996
type: Academic Article
type: Article
type: Document
type: Information Resource

Contraction frequency dependence of twitch and diastolic tension in human dilated cardiomyopathy (tension-frequency relation in cardiomyopathy).
PubMed Identifier: 1497569
author list: Mulieri LA, Leavitt BJ, Hasenfuss G, Allen PD, Alpert NR
published in: Basic research in cardiology
information resource reference: Contraction frequency dependence of twitch and diastolic tension in human dilated cardiomyopathy (tension-frequency relation in cardiomyopathy). Basic Res Cardiol. 1992; 87 Suppl 1:199-212.
journal title abbreviation: Basic Res Cardiol
publication date: 1992-01-01T00:00:00
year: 1992
type: Academic Article
type: Article
type: Document
type: Information Resource

Expression of ryanodine receptor RyR3 produces Ca2+ sparks in dyspedic myotubes.
PubMed Identifier: 10811728
author list: Ward CW, Schneider MF, Castillo D, Protasi F, Wang Y, Chen SR, Allen PD
published in: The Journal of physiology
information resource reference: Expression of ryanodine receptor RyR3 produces Ca2+ sparks in dyspedic myotubes. J Physiol. 2000 May 15; 525 Pt 1:91-103.
journal title abbreviation: J Physiol
publication date: 2000-05-15T00:00:00
year: 2000
type: Academic Article
type: Article
type: Document
type: Information Resource

Maurocalcine and peptide A stabilize distinct subconductance states of ryanodine receptor type 1, revealing a proportional gating mechanism.
PubMed Identifier: 12586831
author list: Chen L, Estève E, Sabatier JM, Ronjat M, De Waard M, Allen PD, Pessah IN
published in: The Journal of biological chemistry
information resource reference: Maurocalcine and peptide A stabilize distinct subconductance states of ryanodine receptor type 1, revealing a proportional gating mechanism. J Biol Chem. 2003 May 02; 278(18):16095-106.
journal title abbreviation: J Biol Chem
publication date: 2003-02-13T00:00:00
year: 2003
type: Academic Article
type: Article
type: Document
type: Information Resource

Not all sudden death is the same.
PubMed Identifier: 14500330
author list: Allen PD
published in: Circulation research
information resource reference: Not all sudden death is the same. Circ Res. 2003 Sep 19; 93(6):484-6.
journal title abbreviation: Circ Res
publication date: 2003-09-19T00:00:00
year: 2003
type: Academic Article
type: Article
type: Document
type: Information Resource

Structural determinants of 4-chloro-m-cresol required for activation of ryanodine receptor type 1.
PubMed Identifier: 16601083
author list: Jacobson AR, Moe ST, Allen PD, Fessenden JD
published in: Molecular pharmacology
information resource reference: Structural determinants of 4-chloro-m-cresol required for activation of ryanodine receptor type 1. Mol Pharmacol. 2006 Jul; 70(1):259-66.
journal title abbreviation: Mol Pharmacol
publication date: 2006-04-06T00:00:00
year: 2006
type: Academic Article
type: Article
type: Document
type: Information Resource

TRPC3-interacting triadic proteins in skeletal muscle.
PubMed Identifier: 18215135
author list: Woo JS, Kim DH, Allen PD, Lee EH
published in: The Biochemical journal
information resource reference: TRPC3-interacting triadic proteins in skeletal muscle. Biochem J. 2008 Apr 15; 411(2):399-405.
journal title abbreviation: Biochem J
publication date: 2008-04-15T00:00:00
year: 2008
type: Academic Article
type: Article
type: Document
type: Information Resource

Adult muscle 'stem' cells can be sustained in culture as free-floating myospheres.
PubMed Identifier: 20381487
author list: Westerman KA, Penvose A, Yang Z, Allen PD, Vacanti CA
published in: Experimental cell research
information resource reference: Adult muscle 'stem' cells can be sustained in culture as free-floating myospheres. Exp Cell Res. 2010 Jul 15; 316(12):1966-76.
journal title abbreviation: Exp Cell Res
publication date: 2010-04-08T00:00:00
year: 2010
type: Academic Article
type: Article
type: Document
type: Information Resource

Reduced gain of excitation-contraction coupling in triadin-null myotubes is mediated by the disruption of FKBP12/RyR1 interaction.
PubMed Identifier: 21310482
author list: Eltit JM, Szpyt J, Li H, Allen PD, Perez CF
published in: Cell calcium
information resource reference: Reduced gain of excitation-contraction coupling in triadin-null myotubes is mediated by the disruption of FKBP12/RyR1 interaction. Cell Calcium. 2011 Feb; 49(2):128-35.
journal title abbreviation: Cell Calcium
publication date: 2011-02-01T00:00:00
year: 2011
type: Academic Article
type: Article
type: Document
type: Information Resource

Muscle Fibers, Skeletal
MeSH DescriptorUI: D018485
MeSH semantic group name: Anatomy
number of authors: 266
number of publications: 566
uniqueness weight: 0.761096
type: Concept

Calcium
MeSH DescriptorUI: D002118
MeSH semantic group name: Chemicals & Drugs
number of authors: 1845
number of publications: 5734
uniqueness weight: 0.392709
type: Concept

Sarcoplasmic Reticulum
MeSH DescriptorUI: D012519
MeSH semantic group name: Anatomy
number of authors: 69
number of publications: 171
uniqueness weight: 0.941639
type: Concept

Ryanodine Receptor Calcium Release Channel
MeSH DescriptorUI: D019837
MeSH semantic group name: Chemicals & Drugs
number of authors: 82
number of publications: 199
uniqueness weight: 0.885791
type: Concept

Malignant Hyperthermia
MeSH DescriptorUI: D008305
MeSH semantic group name: Disorders
number of authors: 43
number of publications: 72
uniqueness weight: 0.961365
type: Concept

Anaesthesia
type: Department
type: Organization

Emeritus
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type: Organization

Medicine
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Neurology
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type: Organization

Surgery
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type: Organization

Joslin
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type: Organization

Beth Israel Deaconess Medical Center
type: Organization

Brigham and Women's Hospital
type: Organization

Harvard Medical School
type: Organization

Joslin Diabetes Center
type: Organization

Massachusetts General Hospital
type: Organization

Vacanti, Charles
eCommons Login: CAV5
first name: Charles
last name: Vacanti
full name: Charles Alfred Vacanti, M.D.
has faculty rank: Full Professor
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Person ID: 66461
person in primary position: Vandam/Covino Professor of Anaesthesia, Emeritus
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Ingwall, Joanne
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Desai, Sukumar
eCommons Login: SPD2
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last name: Desai
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Person ID: 55783
person in primary position: Associate Professor of Anaesthesia
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Authorship 138642
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linked author: Allen, Paul
linked information resource: Allosterically coupled calcium and magnesium binding sites are unmasked by ryanodine receptor chimeras.

Breakefield, Xandra
eCommons Login: XOB1
first name: Xandra
last name: Breakefield
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person in primary position: Professor of Neurology
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Lieberman, Ellice
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Authorship 121345
type: Authorship
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linked author: Allen, Paul
linked information resource: Troponin T isoform expression in humans. A comparison among normal and failing adult heart, fetal heart, and adult and fetal skeletal muscle.

Hasselgren, Per-Olof
eCommons Login: PH17
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Philip, James
eCommons Login: JHP1
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longitude: -71.10616490000000
Person ID: 11465
person in primary position: Professor of Anaesthesia, Emeritus
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Nascimben, Luigino
eCommons Login: LN2
first name: Luigino
last name: Nascimben
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latitude: 42.33510370000000
longitude: -71.10616490000000
Person ID: 34234
person in primary position: Assistant Professor of Anaesthesia
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Brown, Edward
eCommons Login: EMB6
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last name: Brown
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person in primary position: Professor of Medicine, Emeritus
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Spector, Myron
eCommons Login: MS51
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photo: https://connects.catalyst.harvard.edu/Profiles/profile/Modules/CustomViewPersonGeneralInfo/PhotoHandler.ashx
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person in primary position: Professor of Orthopedic Surgery (Biomaterials), Emeritus
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Goodyear, Laurie
eCommons Login: LJG1
first name: Laurie
last name: Goodyear
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Person ID: 25240
person in primary position: Professor of Medicine
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Rutkove, Seward
eCommons Login: SBR1
first name: Seward
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latitude: 42.34022770000000
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person in primary position: Nancy Lurie Marks Professor of Neurology
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Racowsky, Catherine
eCommons Login: CR5
first name: Catherine
last name: Racowsky
full name: Catherine Racowsky, Ph.D.
has faculty rank: Full Professor
latitude: 42.33510370000000
longitude: -71.10616490000000
Person ID: 62029
person in primary position: Professor of Obstetrics, Gynecology and Reproductive Biology, Emerita
type: Agent
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Authorship 129131
type: Authorship
author rank in publication: 4
linked author: Allen, Paul
linked information resource: Two regions of the ryanodine receptor involved in coupling with L-type Ca2+ channels.

Clapham, David
eCommons Login: DEC3
first name: David
last name: Clapham
full name: David Clapham, M.D., Ph.D.
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latitude: 42.33790000000000
longitude: -71.10590000000000
Person ID: 11196
person in primary position: Aldo R. Castaneda Professor of Cardiovascular Research, Emeritus
type: Agent
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preferred title: Aldo R. Castaneda Professor of Cardiovascular Research, Emeritus

Authorship 138528
type: Authorship
author rank in publication: 5
linked author: Allen, Paul
linked information resource: Divergent functional properties of ryanodine receptor types 1 and 3 expressed in a myogenic cell line.

Authorship 146809
type: Authorship
author rank in publication: 8
linked author: Allen, Paul
linked information resource: Dynamic regulation of ryanodine receptor type 1 (RyR1) channel activity by Homer 1.

Professor of Neurology
is primary position: true
position in department: Neurology
position in division: https://connects.catalyst.harvard.edu/Profiles/profile/1229413
sort order: 1
type: Position
HR job title: Professor of Neurology
position in organization: Massachusetts General Hospital

Assistant Professor of Anaesthesia
is primary position: true
position in department: Anaesthesia
position in division: https://connects.catalyst.harvard.edu/Profiles/profile/1229413
sort order: 1
type: Position
HR job title: Assistant Professor of Anaesthesia
position in organization: Brigham and Women's Hospital

Aldo R. Castaneda Professor of Cardiovascular Research, Emeritus
is primary position: true
position in department: Emeritus
position in division: https://connects.catalyst.harvard.edu/Profiles/profile/1229413
sort order: 1
type: Position
HR job title: Aldo R. Castaneda Professor of Cardiovascular Research, Emeritus
position in organization: Harvard Medical School

Authorship 170803
type: Authorship
author rank in publication: 5
linked author: Allen, Paul
linked information resource: Conformational activation of Ca2+ entry by depolarization of skeletal myotubes.

Authorship 176537
type: Authorship
author rank in publication: 4
linked author: Allen, Paul
linked information resource: Ca2+ influx through alpha1S DHPR may play a role in regulating Ca2+ release from RyR1 in skeletal muscle.

Authorship 181808
type: Authorship
author rank in publication: 4
linked author: Allen, Paul
linked information resource: RyR1/RyR3 chimeras reveal that multiple domains of RyR1 are involved in skeletal-type E-C coupling.

Authorship 146621
type: Authorship
author rank in publication: 7
linked author: Allen, Paul
linked information resource: Conformational coupling of DHPR and RyR1 in skeletal myotubes is influenced by long-range allosterism: evidence for a negative regulatory module.

Authorship 161043
type: Authorship
author rank in publication: 2
linked author: Allen, Paul
linked information resource: Developmental regulation of cardiac calcium channels and contractile sensitivity to [Ca]o.

Authorship 190710
type: Authorship
author rank in publication: 9
linked author: Allen, Paul
linked information resource: HSV-1 amplicon vectors are a highly efficient gene delivery system for skeletal muscle myoblasts and myotubes.

Authorship 146170
type: Authorship
author rank in publication: 5
linked author: Allen, Paul
linked information resource: Herpes simplex virus type 1 amplicon vector-mediated gene transfer to muscle.

Authorship 145793
type: Authorship
author rank in publication: 3
linked author: Allen, Paul
linked information resource: Genomics, proteomics and bioinformatics of human heart failure.

Authorship 158378
type: Authorship
author rank in publication: 3
linked author: Allen, Paul
linked information resource: Interplay between intra- and extracellular calcium ions.

Authorship 246950
type: Authorship
author rank in publication: 7
linked author: Allen, Paul
linked information resource: A malignant hyperthermia-inducing mutation in RYR1 (R163C): alterations in Ca2+ entry, release, and retrograde signaling to the DHPR.

Authorship 226579
type: Authorship
author rank in publication: 3
linked author: Allen, Paul
linked information resource: Structural determinants of 4-chloro-m-cresol required for activation of ryanodine receptor type 1.

Authorship 214805
type: Authorship
author rank in publication: 1
linked author: Allen, Paul
linked information resource: "Noninvasive" testing for malignant hyperthermia susceptibility.

Authorship 188444
type: Authorship
author rank in publication: 6
linked author: Allen, Paul
linked information resource: Ryanodine receptor point mutant E4032A reveals an allosteric interaction with ryanodine.

Authorship 304650
type: Authorship
author rank in publication: 4
linked author: Allen, Paul
linked information resource: Mutational analysis of putative calcium binding motifs within the skeletal ryanodine receptor isoform, RyR1.

Authorship 340995
type: Authorship
author rank in publication: 4
linked author: Allen, Paul
linked information resource: Altered myocardial force-frequency relation in human heart failure.

Associate Professor of Anaesthesia
is primary position: true
position in department: Anaesthesia
position in division: https://connects.catalyst.harvard.edu/Profiles/profile/1229413
sort order: 1
type: Position
HR job title: Associate Professor of Anaesthesia
position in organization: Brigham and Women's Hospital

Authorship 425158
type: Authorship
author rank in publication: 6
linked author: Allen, Paul
linked information resource: Vascular smooth muscle expresses a truncated Na+, K(+)-ATPase alpha-1 subunit isoform.

Boston University, Medical Science
end date: 05/1967
educational organization: Boston University
training location: Boston, MA
type: EducationalTraining
degree earned: BA
major field of degree: Medical Science

Boston University, Medicine
end date: 05/1967
educational organization: Boston University
training location: Boston, MA
type: EducationalTraining
degree earned: MD
major field of degree: Medicine

University of Florida, Physiology
end date: 06/1973
educational organization: University of Florida
training location: Gainesville, FL
type: EducationalTraining
degree earned: PhD
major field of degree: Physiology

Authorship 352189
type: Authorship
author rank in publication: 3
linked author: Allen, Paul
linked information resource: Internal structure and visualization of transmembrane domains of the RyR1 calcium release channel by cryo-EM.

Authorship 35274
type: Authorship
author rank in publication: 6
linked author: Allen, Paul
linked information resource: Pharmacologic and functional characterization of malignant hyperthermia in the R163C RyR1 knock-in mouse.

Authorship 39426
type: Authorship
author rank in publication: 4
linked author: Allen, Paul
linked information resource: Cyclic ADP-ribose induces a larger than normal calcium release in malignant hyperthermia-susceptible skeletal muscle fibers.

Authorship 4439
type: Authorship
author rank in publication: 7
linked author: Allen, Paul
linked information resource: Altered sarcoplasmic reticulum Ca2(+)-ATPase gene expression in the human ventricle during end-stage heart failure.

Authorship 177759
type: Authorship
author rank in publication: 3
linked author: Allen, Paul
linked information resource: Influence of isoproterenol and ouabain on excitation-contraction coupling, cross-bridge function, and energetics in failing human myocardium.

Authorship 492604
type: Authorship
author rank in publication: 6
linked author: Allen, Paul
linked information resource: The human cardiac muscle ryanodine receptor-calcium release channel: identification, primary structure and topological analysis.

Authorship 255142
type: Authorship
author rank in publication: 4
linked author: Allen, Paul
linked information resource: Functional analysis of the R1086H malignant hyperthermia mutation in the DHPR reveals an unexpected influence of the III-IV loop on skeletal muscle EC coupling.

Nancy Lurie Marks Professor of Neurology
is primary position: true
position in department: Neurology
position in division: https://connects.catalyst.harvard.edu/Profiles/profile/1229413
sort order: 1
type: Position
HR job title: Nancy Lurie Marks Professor of Neurology
position in organization: Beth Israel Deaconess Medical Center

Authorship 363185
type: Authorship
author rank in publication: 3
linked author: Allen, Paul
linked information resource: Role of ryanodine receptors in the assembly of calcium release units in skeletal muscle.

George H. A. Clowes, Jr. Distinguished Professor of Surgery
is primary position: true
position in department: Surgery
position in division: https://connects.catalyst.harvard.edu/Profiles/profile/1229413
sort order: 1
type: Position
HR job title: George H. A. Clowes, Jr. Distinguished Professor of Surgery
position in organization: Beth Israel Deaconess Medical Center

Professor of Medicine
is primary position: true
position in department: Medicine
position in division: Joslin
sort order: 1
type: Position
HR job title: Professor of Medicine
position in organization: Joslin Diabetes Center

Authorship 27814
type: Authorship
author rank in publication: 5
linked author: Allen, Paul
linked information resource: A malignant hyperthermia-inducing mutation in RYR1 (R163C): consequent alterations in the functional properties of DHPR channels.

Authorship 34245
type: Authorship
author rank in publication: 3
linked author: Allen, Paul
linked information resource: Expression of functional Na,K-ATPase isozymes in normal human cardiac biopsies.

Authorship 658750
type: Authorship
author rank in publication: 9
linked author: Allen, Paul
linked information resource: Ablation of junctin or triadin is associated with increased cardiac injury following ischaemia/reperfusion.

Authorship 652184
type: Authorship
author rank in publication: 5
linked author: Allen, Paul
linked information resource: Three-dimensional localization of the a and ß subunits and of the II-III loop in the skeletal muscle L-type Ca2+ channel.

Authorship 641866
type: Authorship
author rank in publication: 4
linked author: Allen, Paul
linked information resource: Mice null for calsequestrin 1 exhibit deficits in functional performance and sarcoplasmic reticulum calcium handling.

Authorship 642060
type: Authorship
author rank in publication: 4
linked author: Allen, Paul
linked information resource: Reduced gain of excitation-contraction coupling in triadin-null myotubes is mediated by the disruption of FKBP12/RyR1 interaction.

Authorship 643584
type: Authorship
author rank in publication: 10
linked author: Allen, Paul
linked information resource: Malignant hyperthermia susceptibility arising from altered resting coupling between the skeletal muscle L-type Ca2+ channel and the type 1 ryanodine receptor.

Authorship 653774
type: Authorship
author rank in publication: 8
linked author: Allen, Paul
linked information resource: Ablation of skeletal muscle triadin impairs FKBP12/RyR1 channel interactions essential for maintaining resting cytoplasmic Ca2+.

Authorship 657107
type: Authorship
author rank in publication: 7
linked author: Allen, Paul
linked information resource: Functional and biochemical properties of ryanodine receptor type 1 channels from heterozygous R163C malignant hyperthermia-susceptible mice.

Authorship 652747
type: Authorship
author rank in publication: 6
linked author: Allen, Paul
linked information resource: Impaired Orai1-mediated resting Ca2+ entry reduces the cytosolic [Ca2+] and sarcoplasmic reticulum Ca2+ loading in quiescent junctophilin 1 knock-out myotubes.

Authorship 658278
type: Authorship
author rank in publication: 7
linked author: Allen, Paul
linked information resource: Basal bioenergetic abnormalities in skeletal muscle from ryanodine receptor malignant hyperthermia-susceptible R163C knock-in mice.

Authorship 658762
type: Authorship
author rank in publication: 4
linked author: Allen, Paul
linked information resource: Triadin/Junctin double null mouse reveals a differential role for Triadin and Junctin in anchoring CASQ to the jSR and regulating Ca(2+) homeostasis.

Authorship 664208
type: Authorship
author rank in publication: 6
linked author: Allen, Paul
linked information resource: Orthograde dihydropyridine receptor signal regulates ryanodine receptor passive leak.

Authorship 656139
type: Authorship
author rank in publication: 4
linked author: Allen, Paul
linked information resource: Dynamic measurement of the calcium buffering properties of the sarcoplasmic reticulum in mouse skeletal muscle.

Functional and biochemical properties of ryanodine receptor type 1 channels from heterozygous R163C malignant hyperthermia-susceptible mice.
PubMed Identifier: 21156754
author list: Feng W, Barrientos GC, Cherednichenko G, Yang T, Padilla IT, Truong K, Allen PD, Lopez JR, Pessah IN
published in: Molecular pharmacology
information resource reference: Functional and biochemical properties of ryanodine receptor type 1 channels from heterozygous R163C malignant hyperthermia-susceptible mice. Mol Pharmacol. 2011 Mar; 79(3):420-31.
journal title abbreviation: Mol Pharmacol
publication date: 2010-12-14T00:00:00
year: 2010
type: Academic Article
type: Article
type: Document
type: Information Resource

Basal bioenergetic abnormalities in skeletal muscle from ryanodine receptor malignant hyperthermia-susceptible R163C knock-in mice.
PubMed Identifier: 20978128
author list: Giulivi C, Ross-Inta C, Omanska-Klusek A, Napoli E, Sakaguchi D, Barrientos G, Allen PD, Pessah IN
published in: The Journal of biological chemistry
information resource reference: Basal bioenergetic abnormalities in skeletal muscle from ryanodine receptor malignant hyperthermia-susceptible R163C knock-in mice. J Biol Chem. 2011 Jan 07; 286(1):99-113.
journal title abbreviation: J Biol Chem
publication date: 2010-10-26T00:00:00
year: 2010
type: Academic Article
type: Article
type: Document
type: Information Resource

Dynamic measurement of the calcium buffering properties of the sarcoplasmic reticulum in mouse skeletal muscle.
PubMed Identifier: 23148320
author list: Manno C, Sztretye M, Figueroa L, Allen PD, Ríos E
published in: The Journal of physiology
information resource reference: Dynamic measurement of the calcium buffering properties of the sarcoplasmic reticulum in mouse skeletal muscle. J Physiol. 2013 Jan 15; 591(2):423-42.
journal title abbreviation: J Physiol
publication date: 2012-11-12T00:00:00
year: 2012
type: Academic Article
type: Article
type: Document
type: Information Resource

Ablation of junctin or triadin is associated with increased cardiac injury following ischaemia/reperfusion.
PubMed Identifier: 22411973
author list: Cai WF, Pritchard T, Florea S, Lam CK, Han P, Zhou X, Yuan Q, Lehnart SE, Allen PD, Kranias EG
published in: Cardiovascular research
information resource reference: Ablation of junctin or triadin is associated with increased cardiac injury following ischaemia/reperfusion. Cardiovasc Res. 2012 May 01; 94(2):333-41.
journal title abbreviation: Cardiovasc Res
publication date: 2012-03-12T00:00:00
year: 2012
type: Academic Article
type: Article
type: Document
type: Information Resource

Mice null for calsequestrin 1 exhibit deficits in functional performance and sarcoplasmic reticulum calcium handling.
PubMed Identifier: 22164205
author list: Olojo RO, Ziman AP, Hernández-Ochoa EO, Allen PD, Schneider MF, Ward CW
published in: PloS one
information resource reference: Mice null for calsequestrin 1 exhibit deficits in functional performance and sarcoplasmic reticulum calcium handling. PLoS One. 2011; 6(12):e27036.
journal title abbreviation: PLoS One
publication date: 2011-12-02T00:00:00
year: 2011
type: Academic Article
type: Article
type: Document
type: Information Resource

Malignant hyperthermia susceptibility arising from altered resting coupling between the skeletal muscle L-type Ca2+ channel and the type 1 ryanodine receptor.
PubMed Identifier: 22547813
author list: Eltit JM, Bannister RA, Moua O, Altamirano F, Hopkins PM, Pessah IN, Molinski TF, López JR, Beam KG, Allen PD
published in: Proceedings of the National Academy of Sciences of the United States of America
information resource reference: Malignant hyperthermia susceptibility arising from altered resting coupling between the skeletal muscle L-type Ca2+ channel and the type 1 ryanodine receptor. Proc Natl Acad Sci U S A. 2012 May 15; 109(20):7923-8.
journal title abbreviation: Proc Natl Acad Sci U S A
publication date: 2012-04-30T00:00:00
year: 2012
type: Academic Article
type: Article
type: Document
type: Information Resource

Orthograde dihydropyridine receptor signal regulates ryanodine receptor passive leak.
PubMed Identifier: 21482776
author list: Eltit JM, Li H, Ward CW, Molinski T, Pessah IN, Allen PD, Lopez JR
published in: Proceedings of the National Academy of Sciences of the United States of America
information resource reference: Orthograde dihydropyridine receptor signal regulates ryanodine receptor passive leak. Proc Natl Acad Sci U S A. 2011 Apr 26; 108(17):7046-51.
journal title abbreviation: Proc Natl Acad Sci U S A
publication date: 2011-04-11T00:00:00
year: 2011
type: Academic Article
type: Article
type: Document
type: Information Resource

Impaired Orai1-mediated resting Ca2+ entry reduces the cytosolic [Ca2+] and sarcoplasmic reticulum Ca2+ loading in quiescent junctophilin 1 knock-out myotubes.
PubMed Identifier: 20937810
author list: Li H, Ding X, Lopez JR, Takeshima H, Ma J, Allen PD, Eltit JM
published in: The Journal of biological chemistry
information resource reference: Impaired Orai1-mediated resting Ca2+ entry reduces the cytosolic [Ca2+] and sarcoplasmic reticulum Ca2+ loading in quiescent junctophilin 1 knock-out myotubes. J Biol Chem. 2010 Dec 10; 285(50):39171-9.
journal title abbreviation: J Biol Chem
publication date: 2010-10-11T00:00:00
year: 2010
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 263041
type: Authorship
author rank in publication: 2
linked author: Allen, Paul
linked information resource: https://connects.catalyst.harvard.edu/Profiles/profile/1145083

Authorship 285770
type: Authorship
author rank in publication: 6
linked author: Allen, Paul
linked information resource: Maurocalcine and peptide A stabilize distinct subconductance states of ryanodine receptor type 1, revealing a proportional gating mechanism.

Authorship 347061
type: Authorship
author rank in publication: 2
linked author: Allen, Paul
linked information resource: Expression of dihydropyridine receptor (Ca2+ channel) and calsequestrin genes in the myocardium of patients with end-stage heart failure.

Authorship 196616
type: Authorship
author rank in publication: 1
linked author: Allen, Paul
linked information resource: Perceived exertion associated with breathing hyperoxic mixtures during submaximal work.

Professor of Anaesthesia, Emeritus
is primary position: true
position in department: Emeritus
position in division: https://connects.catalyst.harvard.edu/Profiles/profile/1229413
sort order: 1
type: Position
HR job title: Professor of Anaesthesia, Emeritus
position in organization: Harvard Medical School

Vandam/Covino Professor of Anaesthesia, Emeritus
is primary position: true
position in department: Emeritus
position in division: https://connects.catalyst.harvard.edu/Profiles/profile/1229413
sort order: 1
type: Position
HR job title: Vandam/Covino Professor of Anaesthesia, Emeritus
position in organization: Harvard Medical School

Professor of Obstetrics, Gynecology and Reproductive Biology, Emerita
is primary position: true
position in department: Emeritus
position in division: https://connects.catalyst.harvard.edu/Profiles/profile/1229413
sort order: 1
type: Position
HR job title: Professor of Obstetrics, Gynecology and Reproductive Biology, Emerita
position in organization: Harvard Medical School

Professor of Orthopedic Surgery (Biomaterials), Emeritus
is primary position: true
position in department: Emeritus
position in division: https://connects.catalyst.harvard.edu/Profiles/profile/1229413
sort order: 1
type: Position
HR job title: Professor of Orthopedic Surgery (Biomaterials), Emeritus
position in organization: Harvard Medical School

Professor of Medicine (Physiology), Emerita
is primary position: true
position in department: Emeritus
position in division: https://connects.catalyst.harvard.edu/Profiles/profile/1229413
sort order: 1
type: Position
HR job title: Professor of Medicine (Physiology), Emerita
position in organization: Harvard Medical School

Professor of Obstetrics, Gynecology and Reproductive Biology, Emerita
is primary position: true
position in department: Emeritus
position in division: https://connects.catalyst.harvard.edu/Profiles/profile/1229413
sort order: 1
type: Position
HR job title: Professor of Obstetrics, Gynecology and Reproductive Biology, Emerita
position in organization: Harvard Medical School

Professor of Anaesthesia, Emeritus
is primary position: true
position in department: Emeritus
position in division: https://connects.catalyst.harvard.edu/Profiles/profile/1229413
sort order: 1
type: Position
HR job title: Professor of Anaesthesia, Emeritus
position in organization: Harvard Medical School

Professor of Medicine, Emeritus
is primary position: true
position in department: Emeritus
position in division: https://connects.catalyst.harvard.edu/Profiles/profile/1229413
sort order: 1
type: Position
HR job title: Professor of Medicine, Emeritus
position in organization: Harvard Medical School

Authorship 224016
type: Authorship
author rank in publication: 3
linked author: Allen, Paul
linked information resource: Distribution and function of human ventricular beta adrenergic receptors in congestive heart failure.

Authorship 229358
type: Authorship
author rank in publication: 3
linked author: Allen, Paul
linked information resource: Determinants of cardiovascular stability during abdominal aortic aneurysmectomy (AAA).

Authorship 205806
type: Authorship
author rank in publication: 2
linked author: Allen, Paul
linked information resource: Acute appendicitis in children; a review of 1,165 cases.

Authorship 266206
type: Authorship
author rank in publication: 8
linked author: Allen, Paul
linked information resource: Green tea catechins are potent sensitizers of ryanodine receptor type 1 (RyR1).

Authorship 420116
type: Authorship
author rank in publication: 4
linked author: Allen, Paul
linked information resource: Enhanced response to caffeine and 4-chloro-m-cresol in malignant hyperthermia-susceptible muscle is related in part to chronically elevated resting [Ca2+]i.

Authorship 223376
type: Authorship
author rank in publication: 4
linked author: Allen, Paul
linked information resource: Modulation of cardiovascular function and platelet survival by endogenous prostacyclin released during surgery.

Authorship 233299
type: Authorship
author rank in publication: 5
linked author: Allen, Paul
linked information resource: RyR1-specific requirement for depolarization-induced Ca2+ sparks in urinary bladder smooth muscle.

Authorship 16761
type: Authorship
author rank in publication: 1
linked author: Allen, Paul
linked information resource: Not all sudden death is the same.

Authorship 36430
type: Authorship
author rank in publication: 9
linked author: Allen, Paul
linked information resource: Chemical synthesis and characterization of maurocalcine, a scorpion toxin that activates Ca(2+) release channel/ryanodine receptors.

Authorship 324545
type: Authorship
author rank in publication: 7
linked author: Allen, Paul
linked information resource: Molecular basis of human cardiac troponin T isoforms expressed in the developing, adult, and failing heart.

Authorship 346252
type: Authorship
author rank in publication: 5
linked author: Allen, Paul
linked information resource: [Ca2+]i in muscles of malignant hyperthermia susceptible pigs determined in vivo with Ca2+ selective microelectrodes.

Authorship 459080
type: Authorship
author rank in publication: 7
linked author: Allen, Paul
linked information resource: Reorganized stores and impaired calcium handling in skeletal muscle of mice lacking calsequestrin-1.

Authorship 401014
type: Authorship
author rank in publication: 10
linked author: Allen, Paul
linked information resource: Is mammography painful? A multicenter patient survey.

Authorship 539622
type: Authorship
author rank in publication: 1
linked author: Allen, Paul
linked information resource: Anesthesia and the human genome project: the quest for accurate prediction of drug responses.

Authorship 559975
type: Authorship
author rank in publication: 1
linked author: Allen, Paul
linked information resource: Leaky "feet" and sudden death.

Authorship 34978
type: Authorship
author rank in publication: 11
linked author: Allen, Paul
linked information resource: Triadins modulate intracellular Ca(2+) homeostasis but are not essential for excitation-contraction coupling in skeletal muscle.

Authorship 353928
type: Authorship
author rank in publication: 5
linked author: Allen, Paul
linked information resource: Troponin T isoform expression in the normal and failing human left ventricle: a correlation with myofibrillar ATPase activity.

Authorship 455041
type: Authorship
author rank in publication: 3
linked author: Allen, Paul
linked information resource: Contractility effects of local anesthetics in the presence of sodium channel blockade.

Authorship 43493
type: Authorship
author rank in publication: 5
linked author: Allen, Paul
linked information resource: Role of bone marrow cell trafficking in replenishing skeletal muscle SP and MP cell populations.

Authorship 439660
type: Authorship
author rank in publication: 6
linked author: Allen, Paul
linked information resource: Multiple regions of RyR1 mediate functional and structural interactions with alpha(1S)-dihydropyridine receptors in skeletal muscle.

Authorship 536273
type: Authorship
author rank in publication: 6
linked author: Allen, Paul
linked information resource: Kinetic studies of Ca2+ release from sarcoplasmic reticulum of normal and malignant hyperthermia susceptible pig muscles.

Authorship 57062
type: Authorship
author rank in publication: 4
linked author: Allen, Paul
linked information resource: Dyspedic mouse skeletal muscle expresses major elements of the triadic junction but lacks detectable ryanodine receptor protein and function.

Authorship 8679
type: Authorship
author rank in publication: 5
linked author: Allen, Paul
linked information resource: Elevated resting [Ca(2+)](i) in myotubes expressing malignant hyperthermia RyR1 cDNAs is partially restored by modulation of passive calcium leak from the SR.

Authorship 516194
type: Authorship
author rank in publication: 3
linked author: Allen, Paul
linked information resource: Cardiac gene expression profiling provides evidence for cytokinopathy as a molecular mechanism in Chagas' disease cardiomyopathy.

Authorship 61967
type: Authorship
author rank in publication: 7
linked author: Allen, Paul
linked information resource: Herpes simplex virus type 1/adeno-associated virus rep(+) hybrid amplicon vector improves the stability of transgene expression in human cells by site-specific integration.

Authorship 436716
type: Authorship
author rank in publication: 2
linked author: Allen, Paul
linked information resource: Enhanced excitation-coupled calcium entry in myotubes is associated with expression of RyR1 malignant hyperthermia mutations.

Authorship 460244
type: Authorship
author rank in publication: 2
linked author: Allen, Paul
linked information resource: Dextroamphetamine with morphine: respiratory effects.

Authorship 508784
type: Authorship
author rank in publication: 6
linked author: Allen, Paul
linked information resource: Bastadins relate ryanodine-sensitive and -insensitive Ca2+ efflux pathways in skeletal SR and BC3H1 cells.

Authorship 474315
type: Authorship
author rank in publication: 1
linked author: Allen, Paul
linked information resource: Na,K-ATPase expression in normal and failing human left ventricle.

Authorship 225576
type: Authorship
author rank in publication: 1
linked author: Allen, Paul
linked information resource: Presbycusis phenotypes form a heterogeneous continuum when ordered by degree and configuration of hearing loss.

Authorship 176172
type: Authorship
author rank in publication: 5
linked author: Allen, Paul
linked information resource: Gating of store-operated channels by conformational coupling to ryanodine receptors.

Authorship 540669
type: Authorship
author rank in publication: 3
linked author: Allen, Paul
linked information resource: Ca2+ activation of RyR1 is not necessary for the initiation of skeletal-type excitation-contraction coupling.

Authorship 406580
type: Authorship
author rank in publication: 7
linked author: Allen, Paul
linked information resource: The creatine kinase system in normal and diseased human myocardium.

Authorship 407608
type: Authorship
author rank in publication: 4
linked author: Allen, Paul
linked information resource: FKBP12 binding to RyR1 modulates excitation-contraction coupling in mouse skeletal myotubes.

Authorship 225071
type: Authorship
author rank in publication: 6
linked author: Allen, Paul
linked information resource: RyR1 and RyR3 isoforms provide distinct intracellular Ca2+ signals in HEK 293 cells.

Authorship 525054
type: Authorship
author rank in publication: 4
linked author: Allen, Paul
linked information resource: Hypersensitivity of malignant hyperthermia-susceptible swine skeletal muscle to caffeine is mediated by high resting myoplasmic [Ca2+ ].

Authorship 53175
type: Authorship
author rank in publication: 4
linked author: Allen, Paul
linked information resource: The calmodulin binding region of the skeletal ryanodine receptor acts as a self-modulatory domain.

Authorship 275364
type: Authorship
author rank in publication: 4
linked author: Allen, Paul
linked information resource: All three ryanodine receptor isoforms generate rapid cooling responses in muscle cells.

Authorship 290986
type: Authorship
author rank in publication: 7
linked author: Allen, Paul
linked information resource: Conformation-dependent stability of junctophilin 1 (JP1) and ryanodine receptor type 1 (RyR1) channel complex is mediated by their hyper-reactive thiols.

Authorship 462435
type: Authorship
author rank in publication: 5
linked author: Allen, Paul
linked information resource: Identification of a region of RyR1 that participates in allosteric coupling with the alpha(1S) (Ca(V)1.1) II-III loop.

Authorship 566466
type: Authorship
author rank in publication: 3
linked author: Allen, Paul
linked information resource: High-performance ion-exchange chromatography of myosin using a DEAE-5PW column.

Authorship 568640
type: Authorship
author rank in publication: 2
linked author: Allen, Paul
linked information resource: The relationship between temperature and oxygen uptake of contracting skeletal muscle.

Authorship 22185
type: Authorship
author rank in publication: 2
linked author: Allen, Paul
linked information resource: Myoplasmic free [Ca2+] during a malignant hyperthermia episode in swine.

Authorship 7286
type: Authorship
author rank in publication: 3
linked author: Allen, Paul
linked information resource: TRPC3-interacting triadic proteins in skeletal muscle.

Authorship 76326
type: Authorship
author rank in publication: 6
linked author: Allen, Paul
linked information resource: RyR1-mediated Ca2+ leak and Ca2+ entry determine resting intracellular Ca2+ in skeletal myotubes.

Authorship 105978
type: Authorship
author rank in publication: 2
linked author: Allen, Paul
linked information resource: Microarray gene expression profiles in dilated and hypertrophic cardiomyopathic end-stage heart failure.

Authorship 302071
type: Authorship
author rank in publication: 5
linked author: Allen, Paul
linked information resource: Cellular basis of negative inotropic effect of 2,3-butanedione monoxime in human myocardium.

Authorship 249323
type: Authorship
author rank in publication: 5
linked author: Allen, Paul
linked information resource: 23Na and 39K nuclear magnetic resonance studies of perfused rat hearts. Discrimination of intra- and extracellular ions using a shift reagent.

Authorship 331548
type: Authorship
author rank in publication: 6
linked author: Allen, Paul
linked information resource: Calcium transients in 1B5 myotubes lacking ryanodine receptors are related to inositol trisphosphate receptors.

Authorship 467235
type: Authorship
author rank in publication: 7
linked author: Allen, Paul
linked information resource: Protein kinase C-alpha and -epsilon modulate connexin-43 phosphorylation in human heart.

Authorship 27193
type: Authorship
author rank in publication: 6
linked author: Allen, Paul
linked information resource: Transgenic expression of beta-APP in fast-twitch skeletal muscle leads to calcium dyshomeostasis and IBM-like pathology.

Authorship 29945
type: Authorship
author rank in publication: 6
linked author: Allen, Paul
linked information resource: Altered microRNA expression in human heart disease.

Authorship 246540
type: Authorship
author rank in publication: 8
linked author: Allen, Paul
linked information resource: Creatine kinase system in failing and nonfailing human myocardium.

Authorship 283482
type: Authorship
author rank in publication: 6
linked author: Allen, Paul
linked information resource: Changes in myofibrillar content and Mg-ATPase activity in ventricular tissues from patients with heart failure caused by coronary artery disease, cardiomyopathy, or mitral valve insufficiency.

Authorship 401627
type: Authorship
author rank in publication: 5
linked author: Allen, Paul
linked information resource: Homer regulates gain of ryanodine receptor type 1 channel complex.

Authorship 218883
type: Authorship
author rank in publication: 1
linked author: Allen, Paul
linked information resource: Triadin, not essential, but useful.

Authorship 417250
type: Authorship
author rank in publication: 3
linked author: Allen, Paul
linked information resource: Physostigmine: effectiveness as an antagonist of respiratory depression and psychomotor effects caused by morphine or diazepam.

Authorship 438845
type: Authorship
author rank in publication: 3
linked author: Allen, Paul
linked information resource: Calcium dyshomeostasis in beta-amyloid and tau-bearing skeletal myotubes.

Authorship 517995
type: Authorship
author rank in publication: 7
linked author: Allen, Paul
linked information resource: The ryanodine receptor modulates the spontaneous beating rate of cardiomyocytes during development.

Authorship 405421
type: Authorship
author rank in publication: 5
linked author: Allen, Paul
linked information resource: N-terminal region of FKBP12 is essential for binding to the skeletal ryanodine receptor.

Authorship 87804
type: Authorship
author rank in publication: 5
linked author: Allen, Paul
linked information resource: Autotransplantation in mdx mice of mdx myoblasts genetically corrected by an HSV-1 amplicon vector.

Authorship 280131
type: Authorship
author rank in publication: 6
linked author: Allen, Paul
linked information resource: RYR1 and RYR3 have different roles in the assembly of calcium release units of skeletal muscle.

Authorship 258273
type: Authorship
author rank in publication: 3
linked author: Allen, Paul
linked information resource: Structural characterization of the RyR1-FKBP12 interaction.

Authorship 271273
type: Authorship
author rank in publication: 5
linked author: Allen, Paul
linked information resource: Maintenance of cardiodynamics with aspirin during abdominal aortic aneurysmectomy (AAA).

Authorship 275535
type: Authorship
author rank in publication: 1
linked author: Allen, Paul
linked information resource: EU 4093 decreases intracellular [Ca2+] in skeletal muscle fibers from control and malignant hyperthermia-susceptible swine.

Authorship 451281
type: Authorship
author rank in publication: 6
linked author: Allen, Paul
linked information resource: Troponin T mRNA and protein isoforms in the human left ventricle: pattern of expression in failing and control hearts.

Authorship 481886
type: Authorship
author rank in publication: 5
linked author: Allen, Paul
linked information resource: Identification of a key determinant of ryanodine receptor type 1 required for activation by 4-chloro-m-cresol.

Authorship 484825
type: Authorship
author rank in publication: 4
linked author: Allen, Paul
linked information resource: Frog alpha- and beta-ryanodine receptors provide distinct intracellular Ca2+ signals in a myogenic cell line.

Authorship 390498
type: Authorship
author rank in publication: 5
linked author: Allen, Paul
linked information resource: Contractile impairment and structural alterations of skeletal muscles from knockout mice lacking type 1 and type 3 ryanodine receptors.

Authorship 413787
type: Authorship
author rank in publication: 8
linked author: Allen, Paul
linked information resource: Alpha2delta1 dihydropyridine receptor subunit is a critical element for excitation-coupled calcium entry but not for formation of tetrads in skeletal myotubes.

Authorship 49242
type: Authorship
author rank in publication: 4
linked author: Allen, Paul
linked information resource: Negative inotropic and relaxant effects of cocaine on myopathic human ventricular myocardium and epicardial coronary arteries in vitro.

Authorship 53164
type: Authorship
author rank in publication: 5
linked author: Allen, Paul
linked information resource: Morphology and molecular composition of sarcoplasmic reticulum surface junctions in the absence of DHPR and RyR in mouse skeletal muscle.

Authorship 173690
type: Authorship
author rank in publication: 5
linked author: Allen, Paul
linked information resource: Altered Ca2+ homeostasis in human uremic skeletal muscle: possible involvement of cADPR in elevation of intracellular resting [Ca2+].

Authorship 290998
type: Authorship
author rank in publication: 3
linked author: Allen, Paul
linked information resource: Properties of adult rat ventricular cells in long-term culture.

Authorship 339019
type: Authorship
author rank in publication: 4
linked author: Allen, Paul
linked information resource: Adult muscle 'stem' cells can be sustained in culture as free-floating myospheres.

Authorship 379153
type: Authorship
author rank in publication: 7
linked author: Allen, Paul
linked information resource: Type 1 and type 3 ryanodine receptors generate different Ca(2+) release event activity in both intact and permeabilized myotubes.

Authorship 379711
type: Authorship
author rank in publication: 3
linked author: Allen, Paul
linked information resource: Modulation by the thyroid state of intracellular calcium and contractility in ferret ventricular muscle.

Authorship 458866
type: Authorship
author rank in publication: 6
linked author: Allen, Paul
linked information resource: Enhanced dihydropyridine receptor channel activity in the presence of ryanodine receptor.

Authorship 487622
type: Authorship
author rank in publication: 2
linked author: Allen, Paul
linked information resource: Global gene expression profiling of end-stage dilated cardiomyopathy using a human cardiovascular-based cDNA microarray.

Authorship 54288
type: Authorship
author rank in publication: 4
linked author: Allen, Paul
linked information resource: Amino acid residues Gln4020 and Lys4021 of the ryanodine receptor type 1 are required for activation by 4-chloro-m-cresol.

Authorship 577022
type: Authorship
author rank in publication: 4
linked author: Allen, Paul
linked information resource: Effects of dantrolene on myoplasmic free [Ca2+] measured in vivo in patients susceptible to malignant hyperthermia.

Authorship 70777
type: Authorship
author rank in publication: 5
linked author: Allen, Paul
linked information resource: Bidirectional signaling between calcium channels of skeletal muscle requires multiple direct and indirect interactions.

Authorship 363487
type: Authorship
author rank in publication: 4
linked author: Allen, Paul
linked information resource: Skeletal actin mRNA increases in the human heart during ontogenic development and is the major isoform of control and failing adult hearts.

Authorship 481883
type: Authorship
author rank in publication: 2
linked author: Allen, Paul
linked information resource: Homo-dimerization of RyR1 C-terminus via charged residues in random coils or in an alpha-helix.

Authorship 487975
type: Authorship
author rank in publication: 3
linked author: Allen, Paul
linked information resource: Expression levels of RyR1 and RyR3 control resting free Ca2+ in skeletal muscle.

Authorship 464670
type: Authorship
author rank in publication: 5
linked author: Allen, Paul
linked information resource: Functional nonequality of the cardiac and skeletal ryanodine receptors.

Authorship 49332
type: Authorship
author rank in publication: 4
linked author: Allen, Paul
linked information resource: Alteration of contractile function and excitation-contraction coupling in dilated cardiomyopathy.

Authorship 554004
type: Authorship
author rank in publication: 3
linked author: Allen, Paul
linked information resource: Troponin I phosphorylation in the normal and failing adult human heart.

Authorship 316710
type: Authorship
author rank in publication: 6
linked author: Allen, Paul
linked information resource: The gene encoding endothelial nitric oxide synthase, Nos3, maps to rat chromosome 4.

Authorship 326129
type: Authorship
author rank in publication: 8
linked author: Allen, Paul
linked information resource: Enhanced excitation-coupled calcium entry in myotubes expressing malignant hyperthermia mutation R163C is attenuated by dantrolene.

Authorship 349811
type: Authorship
author rank in publication: 7
linked author: Allen, Paul
linked information resource: Molecular cloning and characterization of a human brain ryanodine receptor.

Authorship 185746
type: Authorship
author rank in publication: 5
linked author: Allen, Paul
linked information resource: Occurrence of atypical Ca2+ transients in triadin-binding deficient-RYR1 mutants.

Authorship 3686
type: Authorship
author rank in publication: 10
linked author: Allen, Paul
linked information resource: Heart and skeletal muscle are targets of dengue virus infection.

Authorship 41552
type: Authorship
author rank in publication: 5
linked author: Allen, Paul
linked information resource: Myoplasmic calcium changes precede metabolic and clinical signs of porcine malignant hyperthermia.

Assistant Professor
sort order: 2
type: Faculty Rank

Associate Professor
sort order: 1
type: Faculty Rank

Full Professor
sort order: 0
type: Faculty Rank

Authorship 527664
type: Authorship
author rank in publication: 4
linked author: Allen, Paul
linked information resource: Functional coupling between TRPC3 and RyR1 regulates the expressions of key triadic proteins.

Authorship 484705
type: Authorship
author rank in publication: 4
linked author: Allen, Paul
linked information resource: Contraction frequency dependence of twitch and diastolic tension in human dilated cardiomyopathy (tension-frequency relation in cardiomyopathy).

Authorship 50424
type: Authorship
author rank in publication: 5
linked author: Allen, Paul
linked information resource: Targeted transgene integration into transgenic mouse fibroblasts carrying the full-length human AAVS1 locus mediated by HSV/AAV rep(+) hybrid amplicon vector.

MOLECULAR &ENVIRONMENTAL FACTORS INFLUENCING MH
end date: 2005-02-28
principal investigator name: ALLEN, PAUL D
start date: 2000-03-10
type: Grant
sponsor award id: R01AR046513

Mechanisms controlling Ca2+ dyshomeostasis in MH susceptible mice
end date: 2021-08-31
principal investigator name: ALLEN, PAUL D
start date: 2016-11-01
type: Grant
sponsor award id: R01AR068897

Dihydropyridine receptors and slow calcium signals
end date: 2008-08-31
principal investigator name: ALLEN, PAUL D
start date: 2004-09-01
type: Grant
sponsor award id: R03TW006437

Structure Function Studies of RyR1 in a Myogenic Knockout
end date: 2012-03-31
principal investigator name: ALLEN, PAUL D
start date: 1996-04-01
type: Grant
sponsor award id: R01AR043140

Muscle: Excitation/Contraction Coupling Gordon Research Conference
end date: 2012-08-31
principal investigator name: ALLEN, PAUL D
start date: 2011-09-20
type: Grant
sponsor award id: R13AR062438

E-C Coupling: Signaling Between Calcium Channels
end date: 2009-08-31
principal investigator name: ALLEN, PAUL D
start date: 1997-09-08
type: Grant
sponsor award id: P01AR044750

Integral membrane protein overexpression using organ bioreactors
end date: 2010-07-31
principal investigator name: ALLEN, PAUL D
start date: 2007-09-15
type: Grant
sponsor award id: R01GM081819

Uncovering the Molecular Basis of Malignant Hyperthermia
end date: 2018-05-31
principal investigator name: PESSAH, ISAAC N
start date: 2005-01-01
type: Grant
sponsor award id: P01AR052354

Co-Principal Investigator
type: Researcher Role
researcher role of: Allen, Paul
contributes to: Uncovering the Molecular Basis of Malignant Hyperthermia

Principal Investigator
type: Researcher Role
researcher role of: Allen, Paul
contributes to: Muscle: Excitation/Contraction Coupling Gordon Research Conference

Principal Investigator
type: Researcher Role
researcher role of: Allen, Paul
contributes to: Mechanisms controlling Ca2+ dyshomeostasis in MH susceptible mice

Principal Investigator
type: Researcher Role
researcher role of: Allen, Paul
contributes to: E-C Coupling: Signaling Between Calcium Channels

Principal Investigator
type: Researcher Role
researcher role of: Allen, Paul
contributes to: Dihydropyridine receptors and slow calcium signals

Principal Investigator
type: Researcher Role
researcher role of: Allen, Paul
contributes to: Integral membrane protein overexpression using organ bioreactors

Principal Investigator
type: Researcher Role
researcher role of: Allen, Paul
contributes to: Structure Function Studies of RyR1 in a Myogenic Knockout

Principal Investigator
type: Researcher Role
researcher role of: Allen, Paul
contributes to: MOLECULAR &ENVIRONMENTAL FACTORS INFLUENCING MH

Authorship 69845
type: Authorship
author rank in publication: 2
linked author: Allen, Paul
linked information resource: Cardiac calcium release channel (ryanodine receptor) in control and cardiomyopathic human hearts: mRNA and protein contents are differentially regulated.

Authorship 84949
type: Authorship
author rank in publication: 13
linked author: Allen, Paul
linked information resource: Ablation of triadin causes loss of cardiac Ca2+ release units, impaired excitation-contraction coupling, and cardiac arrhythmias.

Authorship 419968
type: Authorship
author rank in publication: 3
linked author: Allen, Paul
linked information resource: Humoral blockade on lethal pulmonary embolism in the awake dog.

Authorship 43107
type: Authorship
author rank in publication: 3
linked author: Allen, Paul
linked information resource: Abnormal intracellular calcium handling, a major cause of systolic and diastolic dysfunction in ventricular myocardium from patients with heart failure.

Authorship 540282
type: Authorship
author rank in publication: 3
linked author: Allen, Paul
linked information resource: Amino acids 1-1,680 of ryanodine receptor type 1 hold critical determinants of skeletal type for excitation-contraction coupling. Role of divergence domain D2.

Authorship 553777
type: Authorship
author rank in publication: 3
linked author: Allen, Paul
linked information resource: Effects of milrinone on Ca++-sensitivity of myofibrillar Mg-adenosine triphosphatase isolated from normal human and canine hearts.

Authorship 90448
type: Authorship
author rank in publication: 4
linked author: Allen, Paul
linked information resource: Inhibition of the creatine kinase reaction decreases the contractile reserve of isolated rat hearts.

Authorship 346498
type: Authorship
author rank in publication: 4
linked author: Allen, Paul
linked information resource: Coordinated movement of cytoplasmic and transmembrane domains of RyR1 upon gating.

Authorship 36226
type: Authorship
author rank in publication: 10
linked author: Allen, Paul
linked information resource: Neuromuscular development in the avian paralytic mutant crooked neck dwarf (cn/cn): further evidence for the role of neuromuscular activity in motoneuron survival.

Authorship 378652
type: Authorship
author rank in publication: 3
linked author: Allen, Paul
linked information resource: Transmembrane redox sensor of ryanodine receptor complex.

Authorship 444103
type: Authorship
author rank in publication: 4
linked author: Allen, Paul
linked information resource: Functional defects in six ryanodine receptor isoform-1 (RyR1) mutations associated with malignant hyperthermia and their impact on skeletal excitation-contraction coupling.

Authorship 48278
type: Authorship
author rank in publication: 2
linked author: Allen, Paul
linked information resource: Expression of A-, B-, and C-type natriuretic peptide genes in failing and developing human ventricles. Correlation with expression of the Ca(2+)-ATPase gene.

Authorship 525829
type: Authorship
author rank in publication: 8
linked author: Allen, Paul
linked information resource: https://connects.catalyst.harvard.edu/Profiles/profile/1144951

Authorship 529915
type: Authorship
author rank in publication: 4
linked author: Allen, Paul
linked information resource: Comparison of contractile state and myosin isozymes of rat right and left ventricular myocardium.

Authorship 539788
type: Authorship
author rank in publication: 4
linked author: Allen, Paul
linked information resource: Dynamics of transgene expression in human glioblastoma cells mediated by herpes simplex virus/adeno-associated virus amplicon vectors.

The human cardiac muscle ryanodine receptor-calcium release channel: identification, primary structure and topological analysis.
PubMed Identifier: 8809036
author list: Tunwell RE, Wickenden C, Bertrand BM, Shevchenko VI, Walsh MB, Allen PD, Lai FA
published in: The Biochemical journal
information resource reference: The human cardiac muscle ryanodine receptor-calcium release channel: identification, primary structure and topological analysis. Biochem J. 1996 Sep 01; 318 ( Pt 2):477-87.
journal title abbreviation: Biochem J
publication date: 1996-09-01T00:00:00
year: 1996
type: Academic Article
type: Article
type: Document
type: Information Resource

Creatine kinase system in failing and nonfailing human myocardium.
PubMed Identifier: 8873665
author list: Nascimben L, Ingwall JS, Pauletto P, Friedrich J, Gwathmey JK, Saks V, Pessina AC, Allen PD
published in: Circulation
information resource reference: Creatine kinase system in failing and nonfailing human myocardium. Circulation. 1996 Oct 15; 94(8):1894-901.
journal title abbreviation: Circulation
publication date: 1996-10-15T00:00:00
year: 1996
type: Academic Article
type: Article
type: Document
type: Information Resource

Functional nonequality of the cardiac and skeletal ryanodine receptors.
PubMed Identifier: 9023375
author list: Nakai J, Ogura T, Protasi F, Franzini-Armstrong C, Allen PD, Beam KG
published in: Proceedings of the National Academy of Sciences of the United States of America
information resource reference: Functional nonequality of the cardiac and skeletal ryanodine receptors. Proc Natl Acad Sci U S A. 1997 Feb 04; 94(3):1019-22.
journal title abbreviation: Proc Natl Acad Sci U S A
publication date: 1997-02-04T00:00:00
year: 1997
type: Academic Article
type: Article
type: Document
type: Information Resource

Bastadins relate ryanodine-sensitive and -insensitive Ca2+ efflux pathways in skeletal SR and BC3H1 cells.
PubMed Identifier: 9124304
author list: Pessah IN, Molinski TF, Meloy TD, Wong P, Buck ED, Allen PD, Mohr FC, Mack MM
published in: The American journal of physiology
information resource reference: Bastadins relate ryanodine-sensitive and -insensitive Ca2+ efflux pathways in skeletal SR and BC3H1 cells. Am J Physiol. 1997 Feb; 272(2 Pt 1):C601-14.
journal title abbreviation: Am J Physiol
publication date: 1997-02-01T00:00:00
year: 1997
type: Academic Article
type: Article
type: Document
type: Information Resource

Cyclic ADP-ribose induces a larger than normal calcium release in malignant hyperthermia-susceptible skeletal muscle fibers.
PubMed Identifier: 10898524
author list: López JR, Cordovez G, Linares N, Allen PD
published in: Pflugers Archiv : European journal of physiology
information resource reference: Cyclic ADP-ribose induces a larger than normal calcium release in malignant hyperthermia-susceptible skeletal muscle fibers. Pflugers Arch. 2000 Jun; 440(2):236-42.
journal title abbreviation: Pflugers Arch
publication date: 2000-06-01T00:00:00
year: 2000
type: Academic Article
type: Article
type: Document
type: Information Resource

Herpes simplex virus type 1/adeno-associated virus rep(+) hybrid amplicon vector improves the stability of transgene expression in human cells by site-specific integration.
PubMed Identifier: 12072515
author list: Wang Y, Camp SM, Niwano M, Shen X, Bakowska JC, Breakefield XO, Allen PD
published in: Journal of virology
information resource reference: Herpes simplex virus type 1/adeno-associated virus rep(+) hybrid amplicon vector improves the stability of transgene expression in human cells by site-specific integration. J Virol. 2002 Jul; 76(14):7150-62.
journal title abbreviation: J Virol
publication date: 2002-07-01T00:00:00
year: 2002
type: Academic Article
type: Article
type: Document
type: Information Resource

Identification of a key determinant of ryanodine receptor type 1 required for activation by 4-chloro-m-cresol.
PubMed Identifier: 12761215
author list: Fessenden JD, Perez CF, Goth S, Pessah IN, Allen PD
published in: The Journal of biological chemistry
information resource reference: Identification of a key determinant of ryanodine receptor type 1 required for activation by 4-chloro-m-cresol. J Biol Chem. 2003 Aug 01; 278(31):28727-35.
journal title abbreviation: J Biol Chem
publication date: 2003-05-21T00:00:00
year: 2003
type: Academic Article
type: Article
type: Document
type: Information Resource

Molecular cloning and characterization of a human brain ryanodine receptor.
PubMed Identifier: 9395096
author list: Nakashima Y, Nishimura S, Maeda A, Barsoumian EL, Hakamata Y, Nakai J, Allen PD, Imoto K, Kita T
published in: FEBS letters
information resource reference: Molecular cloning and characterization of a human brain ryanodine receptor. FEBS Lett. 1997 Nov 03; 417(1):157-62.
journal title abbreviation: FEBS Lett
publication date: 1997-11-03T00:00:00
year: 1997
type: Academic Article
type: Article
type: Document
type: Information Resource

Transmembrane redox sensor of ryanodine receptor complex.
PubMed Identifier: 10998414
author list: Feng W, Liu G, Allen PD, Pessah IN
published in: The Journal of biological chemistry
information resource reference: Transmembrane redox sensor of ryanodine receptor complex. J Biol Chem. 2000 Nov 17; 275(46):35902-7.
journal title abbreviation: J Biol Chem
publication date: 2000-11-17T00:00:00
year: 2000
type: Academic Article
type: Article
type: Document
type: Information Resource

Mutational analysis of putative calcium binding motifs within the skeletal ryanodine receptor isoform, RyR1.
PubMed Identifier: 15469935
author list: Fessenden JD, Feng W, Pessah IN, Allen PD
published in: The Journal of biological chemistry
information resource reference: Mutational analysis of putative calcium binding motifs within the skeletal ryanodine receptor isoform, RyR1. J Biol Chem. 2004 Dec 17; 279(51):53028-35.
journal title abbreviation: J Biol Chem
publication date: 2004-10-06T00:00:00
year: 2004
type: Academic Article
type: Article
type: Document
type: Information Resource

Pharmacologic and functional characterization of malignant hyperthermia in the R163C RyR1 knock-in mouse.
PubMed Identifier: 17122579
author list: Yang T, Riehl J, Esteve E, Matthaei KI, Goth S, Allen PD, Pessah IN, Lopez JR
published in: Anesthesiology
information resource reference: Pharmacologic and functional characterization of malignant hyperthermia in the R163C RyR1 knock-in mouse. Anesthesiology. 2006 Dec; 105(6):1164-75.
journal title abbreviation: Anesthesiology
publication date: 2006-12-01T00:00:00
year: 2006
type: Academic Article
type: Article
type: Document
type: Information Resource

Cardiac calcium release channel (ryanodine receptor) in control and cardiomyopathic human hearts: mRNA and protein contents are differentially regulated.
PubMed Identifier: 9160875
author list: Sainte Beuve C, Allen PD, Dambrin G, Rannou F, Marty I, Trouvé P, Bors V, Pavie A, Gandgjbakch I, Charlemagne D
published in: Journal of molecular and cellular cardiology
information resource reference: Cardiac calcium release channel (ryanodine receptor) in control and cardiomyopathic human hearts: mRNA and protein contents are differentially regulated. J Mol Cell Cardiol. 1997 Apr; 29(4):1237-46.
journal title abbreviation: J Mol Cell Cardiol
publication date: 1997-04-01T00:00:00
year: 1997
type: Academic Article
type: Article
type: Document
type: Information Resource

Ryanodine receptor point mutant E4032A reveals an allosteric interaction with ryanodine.
PubMed Identifier: 11226332
author list: Fessenden JD, Chen L, Wang Y, Paolini C, Franzini-Armstrong C, Allen PD, Pessah IN
published in: Proceedings of the National Academy of Sciences of the United States of America
information resource reference: Ryanodine receptor point mutant E4032A reveals an allosteric interaction with ryanodine. Proc Natl Acad Sci U S A. 2001 Feb 27; 98(5):2865-70.
journal title abbreviation: Proc Natl Acad Sci U S A
publication date: 2001-02-13T00:00:00
year: 2001
type: Academic Article
type: Article
type: Document
type: Information Resource

Protein kinase C-alpha and -epsilon modulate connexin-43 phosphorylation in human heart.
PubMed Identifier: 11273731
author list: Bowling N, Huang X, Sandusky GE, Fouts RL, Mintze K, Esterman M, Allen PD, Maddi R, McCall E, Vlahos CJ
published in: Journal of molecular and cellular cardiology
information resource reference: Protein kinase C-alpha and -epsilon modulate connexin-43 phosphorylation in human heart. J Mol Cell Cardiol. 2001 Apr; 33(4):789-98.
journal title abbreviation: J Mol Cell Cardiol
publication date: 2001-04-01T00:00:00
year: 2001
type: Academic Article
type: Article
type: Document
type: Information Resource

Alteration of contractile function and excitation-contraction coupling in dilated cardiomyopathy.
PubMed Identifier: 1576741
author list: Hasenfuss G, Mulieri LA, Leavitt BJ, Allen PD, Haeberle JR, Alpert NR
published in: Circulation research
information resource reference: Alteration of contractile function and excitation-contraction coupling in dilated cardiomyopathy. Circ Res. 1992 Jun; 70(6):1225-32.
journal title abbreviation: Circ Res
publication date: 1992-06-01T00:00:00
year: 1992
type: Academic Article
type: Article
type: Document
type: Information Resource

Vascular smooth muscle expresses a truncated Na+, K(+)-ATPase alpha-1 subunit isoform.
PubMed Identifier: 1655743
author list: Medford RM, Hyman R, Ahmad M, Allen JC, Pressley TA, Allen PD, Nadal-Ginard B
published in: The Journal of biological chemistry
information resource reference: Vascular smooth muscle expresses a truncated Na+, K(+)-ATPase alpha-1 subunit isoform. J Biol Chem. 1991 Sep 25; 266(27):18308-12.
journal title abbreviation: J Biol Chem
publication date: 1991-09-25T00:00:00
year: 1991
type: Academic Article
type: Article
type: Document
type: Information Resource

Altered microRNA expression in human heart disease.
PubMed Identifier: 17712037
author list: Ikeda S, Kong SW, Lu J, Bisping E, Zhang H, Allen PD, Golub TR, Pieske B, Pu WT
published in: Physiological genomics
information resource reference: Altered microRNA expression in human heart disease. Physiol Genomics. 2007 Nov 14; 31(3):367-73.
journal title abbreviation: Physiol Genomics
publication date: 2007-08-21T00:00:00
year: 2007
type: Academic Article
type: Article
type: Document
type: Information Resource

Allosterically coupled calcium and magnesium binding sites are unmasked by ryanodine receptor chimeras.
PubMed Identifier: 18096513
author list: Voss AA, Allen PD, Pessah IN, Perez CF
published in: Biochemical and biophysical research communications
information resource reference: Allosterically coupled calcium and magnesium binding sites are unmasked by ryanodine receptor chimeras. Biochem Biophys Res Commun. 2008 Feb 22; 366(4):988-93.
journal title abbreviation: Biochem Biophys Res Commun
publication date: 2007-12-26T00:00:00
year: 2007
type: Academic Article
type: Article
type: Document
type: Information Resource

Identification of a region of RyR1 that participates in allosteric coupling with the alpha(1S) (Ca(V)1.1) II-III loop.
PubMed Identifier: 11726651
author list: Proenza C, O'Brien J, Nakai J, Mukherjee S, Allen PD, Beam KG
published in: The Journal of biological chemistry
information resource reference: Identification of a region of RyR1 that participates in allosteric coupling with the alpha(1S) (Ca(V)1.1) II-III loop. J Biol Chem. 2002 Feb 22; 277(8):6530-5.
journal title abbreviation: J Biol Chem
publication date: 2001-11-28T00:00:00
year: 2001
type: Academic Article
type: Article
type: Document
type: Information Resource

Anesthesia and the human genome project: the quest for accurate prediction of drug responses.
PubMed Identifier: 15731583
author list: Allen PD
published in: Anesthesiology
information resource reference: Anesthesia and the human genome project: the quest for accurate prediction of drug responses. Anesthesiology. 2005 Mar; 102(3):494-5.
journal title abbreviation: Anesthesiology
publication date: 2005-03-01T00:00:00
year: 2005
type: Academic Article
type: Article
type: Document
type: Information Resource

Gating of store-operated channels by conformational coupling to ryanodine receptors.
PubMed Identifier: 10983988
author list: Kiselyov KI, Shin DM, Wang Y, Pessah IN, Allen PD, Muallem S
published in: Molecular cell
information resource reference: Gating of store-operated channels by conformational coupling to ryanodine receptors. Mol Cell. 2000 Aug; 6(2):421-31.
journal title abbreviation: Mol Cell
publication date: 2000-08-01T00:00:00
year: 2000
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Cellular basis of negative inotropic effect of 2,3-butanedione monoxime in human myocardium.
PubMed Identifier: 1510147
author list: Perreault CL, Mulieri LA, Alpert NR, Ransil BJ, Allen PD, Morgan JP
published in: The American journal of physiology
information resource reference: Cellular basis of negative inotropic effect of 2,3-butanedione monoxime in human myocardium. Am J Physiol. 1992 Aug; 263(2 Pt 2):H503-10.
journal title abbreviation: Am J Physiol
publication date: 1992-08-01T00:00:00
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Microarray gene expression profiles in dilated and hypertrophic cardiomyopathic end-stage heart failure.
PubMed Identifier: 12118103
author list: Hwang JJ, Allen PD, Tseng GC, Lam CW, Fananapazir L, Dzau VJ, Liew CC
published in: Physiological genomics
information resource reference: Microarray gene expression profiles in dilated and hypertrophic cardiomyopathic end-stage heart failure. Physiol Genomics. 2002 Jul 12; 10(1):31-44.
journal title abbreviation: Physiol Genomics
publication date: 2002-07-12T00:00:00
year: 2002
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type: Information Resource

FKBP12 binding to RyR1 modulates excitation-contraction coupling in mouse skeletal myotubes.
PubMed Identifier: 12704193
author list: Avila G, Lee EH, Perez CF, Allen PD, Dirksen RT
published in: The Journal of biological chemistry
information resource reference: FKBP12 binding to RyR1 modulates excitation-contraction coupling in mouse skeletal myotubes. J Biol Chem. 2003 Jun 20; 278(25):22600-8.
journal title abbreviation: J Biol Chem
publication date: 2003-04-17T00:00:00
year: 2003
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Amino acids 1-1,680 of ryanodine receptor type 1 hold critical determinants of skeletal type for excitation-contraction coupling. Role of divergence domain D2.
PubMed Identifier: 12900411
author list: Perez CF, Mukherjee S, Allen PD
published in: The Journal of biological chemistry
information resource reference: Amino acids 1-1,680 of ryanodine receptor type 1 hold critical determinants of skeletal type for excitation-contraction coupling. Role of divergence domain D2. J Biol Chem. 2003 Oct 10; 278(41):39644-52.
journal title abbreviation: J Biol Chem
publication date: 2003-08-04T00:00:00
year: 2003
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Ca2+ influx through alpha1S DHPR may play a role in regulating Ca2+ release from RyR1 in skeletal muscle.
PubMed Identifier: 12954602
author list: Shtifman A, Paolini C, López JR, Allen PD, Protasi F
published in: American journal of physiology. Cell physiology
information resource reference: Ca2+ influx through alpha1S DHPR may play a role in regulating Ca2+ release from RyR1 in skeletal muscle. Am J Physiol Cell Physiol. 2004 Jan; 286(1):C73-8.
journal title abbreviation: Am J Physiol Cell Physiol
publication date: 2003-09-03T00:00:00
year: 2003
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Expression levels of RyR1 and RyR3 control resting free Ca2+ in skeletal muscle.
PubMed Identifier: 15548569
author list: Perez CF, López JR, Allen PD
published in: American journal of physiology. Cell physiology
information resource reference: Expression levels of RyR1 and RyR3 control resting free Ca2+ in skeletal muscle. Am J Physiol Cell Physiol. 2005 Mar; 288(3):C640-9.
journal title abbreviation: Am J Physiol Cell Physiol
publication date: 2004-11-17T00:00:00
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type: Document
type: Information Resource

Dyspedic mouse skeletal muscle expresses major elements of the triadic junction but lacks detectable ryanodine receptor protein and function.
PubMed Identifier: 9054435
author list: Buck ED, Nguyen HT, Pessah IN, Allen PD
published in: The Journal of biological chemistry
information resource reference: Dyspedic mouse skeletal muscle expresses major elements of the triadic junction but lacks detectable ryanodine receptor protein and function. J Biol Chem. 1997 Mar 14; 272(11):7360-7.
journal title abbreviation: J Biol Chem
publication date: 1997-03-14T00:00:00
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Troponin T mRNA and protein isoforms in the human left ventricle: pattern of expression in failing and control hearts.
PubMed Identifier: 9405179
author list: Mesnard-Rouiller L, Mercadier JJ, Butler-Browne G, Heimburger M, Logeart D, Allen PD, Samson F
published in: Journal of molecular and cellular cardiology
information resource reference: Troponin T mRNA and protein isoforms in the human left ventricle: pattern of expression in failing and control hearts. J Mol Cell Cardiol. 1997 Nov; 29(11):3043-55.
journal title abbreviation: J Mol Cell Cardiol
publication date: 1997-11-01T00:00:00
year: 1997
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The ryanodine receptor modulates the spontaneous beating rate of cardiomyocytes during development.
PubMed Identifier: 12089338
author list: Yang HT, Tweedie D, Wang S, Guia A, Vinogradova T, Bogdanov K, Allen PD, Stern MD, Lakatta EG, Boheler KR
published in: Proceedings of the National Academy of Sciences of the United States of America
information resource reference: The ryanodine receptor modulates the spontaneous beating rate of cardiomyocytes during development. Proc Natl Acad Sci U S A. 2002 Jul 09; 99(14):9225-30.
journal title abbreviation: Proc Natl Acad Sci U S A
publication date: 2002-06-27T00:00:00
year: 2002
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RYR1 and RYR3 have different roles in the assembly of calcium release units of skeletal muscle.
PubMed Identifier: 11053125
author list: Protasi F, Takekura H, Wang Y, Chen SR, Meissner G, Allen PD, Franzini-Armstrong C
published in: Biophysical journal
information resource reference: RYR1 and RYR3 have different roles in the assembly of calcium release units of skeletal muscle. Biophys J. 2000 Nov; 79(5):2494-508.
journal title abbreviation: Biophys J
publication date: 2000-11-01T00:00:00
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Role of ryanodine receptors in the assembly of calcium release units in skeletal muscle.
PubMed Identifier: 9472035
author list: Protasi F, Franzini-Armstrong C, Allen PD
published in: The Journal of cell biology
information resource reference: Role of ryanodine receptors in the assembly of calcium release units in skeletal muscle. J Cell Biol. 1998 Feb 23; 140(4):831-42.
journal title abbreviation: J Cell Biol
publication date: 1998-02-23T00:00:00
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Role of bone marrow cell trafficking in replenishing skeletal muscle SP and MP cell populations.
PubMed Identifier: 15054107
author list: Rivier F, Alkan O, Flint AF, Muskiewicz K, Allen PD, Leboulch P, Gussoni E
published in: Journal of cell science
information resource reference: Role of bone marrow cell trafficking in replenishing skeletal muscle SP and MP cell populations. J Cell Sci. 2004 Apr 15; 117(Pt 10):1979-88.
journal title abbreviation: J Cell Sci
publication date: 2004-03-30T00:00:00
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Morphology and molecular composition of sarcoplasmic reticulum surface junctions in the absence of DHPR and RyR in mouse skeletal muscle.
PubMed Identifier: 12023238
author list: Felder E, Protasi F, Hirsch R, Franzini-Armstrong C, Allen PD
published in: Biophysical journal
information resource reference: Morphology and molecular composition of sarcoplasmic reticulum surface junctions in the absence of DHPR and RyR in mouse skeletal muscle. Biophys J. 2002 Jun; 82(6):3144-9.
journal title abbreviation: Biophys J
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Effects of dantrolene on myoplasmic free [Ca2+] measured in vivo in patients susceptible to malignant hyperthermia.
PubMed Identifier: 1575338
author list: Lopez JR, Gerardi A, Lopez MJ, Allen PD
published in: Anesthesiology
information resource reference: Effects of dantrolene on myoplasmic free [Ca2+] measured in vivo in patients susceptible to malignant hyperthermia. Anesthesiology. 1992 May; 76(5):711-9.
journal title abbreviation: Anesthesiology
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Contractile protein function in failing and nonfailing human myocardium.
PubMed Identifier: 1497566
author list: Hasenfuss G, Mulieri LA, Leavitt BJ, Allen PD, Holubarsch C, Just H, Alpert NR
published in: Basic research in cardiology
information resource reference: Contractile protein function in failing and nonfailing human myocardium. Basic Res Cardiol. 1992; 87 Suppl 1:107-16.
journal title abbreviation: Basic Res Cardiol
publication date: 1992-01-01T00:00:00
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Functional defects in six ryanodine receptor isoform-1 (RyR1) mutations associated with malignant hyperthermia and their impact on skeletal excitation-contraction coupling.
PubMed Identifier: 12732639
author list: Yang T, Ta TA, Pessah IN, Allen PD
published in: The Journal of biological chemistry
information resource reference: Functional defects in six ryanodine receptor isoform-1 (RyR1) mutations associated with malignant hyperthermia and their impact on skeletal excitation-contraction coupling. J Biol Chem. 2003 Jul 11; 278(28):25722-30.
journal title abbreviation: J Biol Chem
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Global gene expression profiling of end-stage dilated cardiomyopathy using a human cardiovascular-based cDNA microarray.
PubMed Identifier: 12057908
author list: Barrans JD, Allen PD, Stamatiou D, Dzau VJ, Liew CC
published in: The American journal of pathology
information resource reference: Global gene expression profiling of end-stage dilated cardiomyopathy using a human cardiovascular-based cDNA microarray. Am J Pathol. 2002 Jun; 160(6):2035-43.
journal title abbreviation: Am J Pathol
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Na,K-ATPase expression in normal and failing human left ventricle.
PubMed Identifier: 1323267
author list: Allen PD, Schmidt TA, Marsh JD, Kjeldsen K
published in: Basic research in cardiology
information resource reference: Na,K-ATPase expression in normal and failing human left ventricle. Basic Res Cardiol. 1992; 87 Suppl 1:87-94.
journal title abbreviation: Basic Res Cardiol
publication date: 1992-01-01T00:00:00
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Neuromuscular development in the avian paralytic mutant crooked neck dwarf (cn/cn): further evidence for the role of neuromuscular activity in motoneuron survival.
PubMed Identifier: 9133573
author list: Oppenheim RW, Prevette D, Houenou LJ, Pincon-Raymond M, Dimitriadou V, Donevan A, O'Donovan M, Wenner P, Mckemy DD, Allen PD
published in: The Journal of comparative neurology
information resource reference: Neuromuscular development in the avian paralytic mutant crooked neck dwarf (cn/cn): further evidence for the role of neuromuscular activity in motoneuron survival. J Comp Neurol. 1997 May 12; 381(3):353-72.
journal title abbreviation: J Comp Neurol
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Chemical synthesis and characterization of maurocalcine, a scorpion toxin that activates Ca(2+) release channel/ryanodine receptors.
PubMed Identifier: 10713267
author list: Fajloun Z, Kharrat R, Chen L, Lecomte C, Di Luccio E, Bichet D, El Ayeb M, Rochat H, Allen PD, Pessah IN, De Waard M, Sabatier JM
published in: FEBS letters
information resource reference: Chemical synthesis and characterization of maurocalcine, a scorpion toxin that activates Ca(2+) release channel/ryanodine receptors. FEBS Lett. 2000 Mar 10; 469(2-3):179-85.
journal title abbreviation: FEBS Lett
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Dynamics of transgene expression in human glioblastoma cells mediated by herpes simplex virus/adeno-associated virus amplicon vectors.
PubMed Identifier: 12542846
author list: Lam P, Hui KM, Wang Y, Allen PD, Louis DN, Yuan CJ, Breakefield XO
published in: Human gene therapy
information resource reference: Dynamics of transgene expression in human glioblastoma cells mediated by herpes simplex virus/adeno-associated virus amplicon vectors. Hum Gene Ther. 2002 Dec 10; 13(18):2147-59.
journal title abbreviation: Hum Gene Ther
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Ablation of skeletal muscle triadin impairs FKBP12/RyR1 channel interactions essential for maintaining resting cytoplasmic Ca2+.
PubMed Identifier: 20926377
author list: Eltit JM, Feng W, Lopez JR, Padilla IT, Pessah IN, Molinski TF, Fruen BR, Allen PD, Perez CF
published in: The Journal of biological chemistry
information resource reference: Ablation of skeletal muscle triadin impairs FKBP12/RyR1 channel interactions essential for maintaining resting cytoplasmic Ca2+. J Biol Chem. 2010 Dec 03; 285(49):38453-62.
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High-performance ion-exchange chromatography of myosin using a DEAE-5PW column.
PubMed Identifier: 2793983
author list: Lema MJ, Pluskal MG, Allen PD
published in: Journal of chromatography
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journal title abbreviation: J Chromatogr
publication date: 1989-06-30T00:00:00
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"Noninvasive" testing for malignant hyperthermia susceptibility.
PubMed Identifier: 12411783
author list: Allen PD, López JR
published in: Anesthesiology
information resource reference: "Noninvasive" testing for malignant hyperthermia susceptibility. Anesthesiology. 2002 Nov; 97(5):1045-6.
journal title abbreviation: Anesthesiology
publication date: 2002-11-01T00:00:00
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Functional analysis of the R1086H malignant hyperthermia mutation in the DHPR reveals an unexpected influence of the III-IV loop on skeletal muscle EC coupling.
PubMed Identifier: 15201141
author list: Weiss RG, O'Connell KM, Flucher BE, Allen PD, Grabner M, Dirksen RT
published in: American journal of physiology. Cell physiology
information resource reference: Functional analysis of the R1086H malignant hyperthermia mutation in the DHPR reveals an unexpected influence of the III-IV loop on skeletal muscle EC coupling. Am J Physiol Cell Physiol. 2004 Oct; 287(4):C1094-102.
journal title abbreviation: Am J Physiol Cell Physiol
publication date: 2004-06-16T00:00:00
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Internal structure and visualization of transmembrane domains of the RyR1 calcium release channel by cryo-EM.
PubMed Identifier: 15908964
author list: Samsó M, Wagenknecht T, Allen PD
published in: Nature structural & molecular biology
information resource reference: Internal structure and visualization of transmembrane domains of the RyR1 calcium release channel by cryo-EM. Nat Struct Mol Biol. 2005 Jun; 12(6):539-44.
journal title abbreviation: Nat Struct Mol Biol
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Interplay between intra- and extracellular calcium ions.
PubMed Identifier: 16819293
author list: Lee EH, Kim DH, Allen PD
published in: Molecules and cells
information resource reference: Interplay between intra- and extracellular calcium ions. Mol Cells. 2006 Jun 30; 21(3):315-29.
journal title abbreviation: Mol Cells
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Altered sarcoplasmic reticulum Ca2(+)-ATPase gene expression in the human ventricle during end-stage heart failure.
PubMed Identifier: 2136864
author list: Mercadier JJ, Lompré AM, Duc P, Boheler KR, Fraysse JB, Wisnewsky C, Allen PD, Komajda M, Schwartz K
published in: The Journal of clinical investigation
information resource reference: Altered sarcoplasmic reticulum Ca2(+)-ATPase gene expression in the human ventricle during end-stage heart failure. J Clin Invest. 1990 Jan; 85(1):305-9.
journal title abbreviation: J Clin Invest
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Elevated resting [Ca(2+)](i) in myotubes expressing malignant hyperthermia RyR1 cDNAs is partially restored by modulation of passive calcium leak from the SR.
PubMed Identifier: 17182726
author list: Yang T, Esteve E, Pessah IN, Molinski TF, Allen PD, López JR
published in: American journal of physiology. Cell physiology
information resource reference: Elevated resting [Ca(2+)](i) in myotubes expressing malignant hyperthermia RyR1 cDNAs is partially restored by modulation of passive calcium leak from the SR. Am J Physiol Cell Physiol. 2007 May; 292(5):C1591-8.
journal title abbreviation: Am J Physiol Cell Physiol
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Targeted transgene integration into transgenic mouse fibroblasts carrying the full-length human AAVS1 locus mediated by HSV/AAV rep(+) hybrid amplicon vector.
PubMed Identifier: 12923568
author list: Bakowska JC, Di Maria MV, Camp SM, Wang Y, Allen PD, Breakefield XO
published in: Gene therapy
information resource reference: Targeted transgene integration into transgenic mouse fibroblasts carrying the full-length human AAVS1 locus mediated by HSV/AAV rep(+) hybrid amplicon vector. Gene Ther. 2003 Sep; 10(19):1691-702.
journal title abbreviation: Gene Ther
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Properties of adult rat ventricular cells in long-term culture.
PubMed Identifier: 2102811
author list: Ikeda U, Briggs GM, Allen PD, Sen L, Medford RM, Smith TW
published in: Cardioscience
information resource reference: Properties of adult rat ventricular cells in long-term culture. Cardioscience. 1990 Sep; 1(3):225-33.
journal title abbreviation: Cardioscience
publication date: 1990-09-01T00:00:00
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Transgenic expression of beta-APP in fast-twitch skeletal muscle leads to calcium dyshomeostasis and IBM-like pathology.
PubMed Identifier: 16940437
author list: Moussa CE, Fu Q, Kumar P, Shtifman A, Lopez JR, Allen PD, LaFerla F, Weinberg D, Magrane J, Aprahamian T, Walsh K, Rosen KM, Querfurth HW
published in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology
information resource reference: Transgenic expression of beta-APP in fast-twitch skeletal muscle leads to calcium dyshomeostasis and IBM-like pathology. FASEB J. 2006 Oct; 20(12):2165-7.
journal title abbreviation: FASEB J
publication date: 2006-08-29T00:00:00
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type: Information Resource

N-terminal region of FKBP12 is essential for binding to the skeletal ryanodine receptor.
PubMed Identifier: 15033987
author list: Lee EH, Rho SH, Kwon SJ, Eom SH, Allen PD, Kim DH
published in: The Journal of biological chemistry
information resource reference: N-terminal region of FKBP12 is essential for binding to the skeletal ryanodine receptor. J Biol Chem. 2004 Jun 18; 279(25):26481-8.
journal title abbreviation: J Biol Chem
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Altered Ca2+ homeostasis in human uremic skeletal muscle: possible involvement of cADPR in elevation of intracellular resting [Ca2+].
PubMed Identifier: 15855809
author list: López JR, Mijares A, Rojas B, Linares N, Allen PD, Shtifman A
published in: Nephron. Physiology
information resource reference: Altered Ca2+ homeostasis in human uremic skeletal muscle: possible involvement of cADPR in elevation of intracellular resting [Ca2+]. Nephron Physiol. 2005; 100(4):p51-60.
journal title abbreviation: Nephron Physiol
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type: Information Resource

Cardiac gene expression profiling provides evidence for cytokinopathy as a molecular mechanism in Chagas' disease cardiomyopathy.
PubMed Identifier: 16049318
author list: Cunha-Neto E, Dzau VJ, Allen PD, Stamatiou D, Benvenutti L, Higuchi ML, Koyama NS, Silva JS, Kalil J, Liew CC
published in: The American journal of pathology
information resource reference: Cardiac gene expression profiling provides evidence for cytokinopathy as a molecular mechanism in Chagas' disease cardiomyopathy. Am J Pathol. 2005 Aug; 167(2):305-13.
journal title abbreviation: Am J Pathol
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23Na and 39K nuclear magnetic resonance studies of perfused rat hearts. Discrimination of intra- and extracellular ions using a shift reagent.
PubMed Identifier: 4016206
author list: Pike MM, Frazer JC, Dedrick DF, Ingwall JS, Allen PD, Springer CS, Smith TW
published in: Biophysical journal
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journal title abbreviation: Biophys J
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Expression of dihydropyridine receptor (Ca2+ channel) and calsequestrin genes in the myocardium of patients with end-stage heart failure.
PubMed Identifier: 1326001
author list: Takahashi T, Allen PD, Lacro RV, Marks AR, Dennis AR, Schoen FJ, Grossman W, Marsh JD, Izumo S
published in: The Journal of clinical investigation
information resource reference: Expression of dihydropyridine receptor (Ca2+ channel) and calsequestrin genes in the myocardium of patients with end-stage heart failure. J Clin Invest. 1992 Sep; 90(3):927-35.
journal title abbreviation: J Clin Invest
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26952 Middle Golf Drive
type: Address
address line 1: Brigham and Women
address line 3: 26952 Middle Golf Drive
city: Davis
postal code: 95618
state or province: CA

Changes in myofibrillar content and Mg-ATPase activity in ventricular tissues from patients with heart failure caused by coronary artery disease, cardiomyopathy, or mitral valve insufficiency.
PubMed Identifier: 2969307
author list: Pagani ED, Alousi AA, Grant AM, Older TM, Dziuban SW, Allen PD
published in: Circulation research
information resource reference: Changes in myofibrillar content and Mg-ATPase activity in ventricular tissues from patients with heart failure caused by coronary artery disease, cardiomyopathy, or mitral valve insufficiency. Circ Res. 1988 Aug; 63(2):380-5.
journal title abbreviation: Circ Res
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HSV-1 amplicon vectors are a highly efficient gene delivery system for skeletal muscle myoblasts and myotubes.
PubMed Identifier: 10712251
author list: Wang Y, Fraefel C, Protasi F, Moore RA, Fessenden JD, Pessah IN, DiFrancesco A, Breakefield X, Allen PD
published in: American journal of physiology. Cell physiology
information resource reference: HSV-1 amplicon vectors are a highly efficient gene delivery system for skeletal muscle myoblasts and myotubes. Am J Physiol Cell Physiol. 2000 Mar; 278(3):C619-26.
journal title abbreviation: Am J Physiol Cell Physiol
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Divergent functional properties of ryanodine receptor types 1 and 3 expressed in a myogenic cell line.
PubMed Identifier: 11053126
author list: Fessenden JD, Wang Y, Moore RA, Chen SR, Allen PD, Pessah IN
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information resource reference: Divergent functional properties of ryanodine receptor types 1 and 3 expressed in a myogenic cell line. Biophys J. 2000 Nov; 79(5):2509-25.
journal title abbreviation: Biophys J
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Altered myocardial force-frequency relation in human heart failure.
PubMed Identifier: 1572031
author list: Mulieri LA, Hasenfuss G, Leavitt B, Allen PD, Alpert NR
published in: Circulation
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journal title abbreviation: Circulation
publication date: 1992-05-01T00:00:00
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Type 1 and type 3 ryanodine receptors generate different Ca(2+) release event activity in both intact and permeabilized myotubes.
PubMed Identifier: 11720987
author list: Ward CW, Protasi F, Castillo D, Wang Y, Chen SR, Pessah IN, Allen PD, Schneider MF
published in: Biophysical journal
information resource reference: Type 1 and type 3 ryanodine receptors generate different Ca(2+) release event activity in both intact and permeabilized myotubes. Biophys J. 2001 Dec; 81(6):3216-30.
journal title abbreviation: Biophys J
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Alpha2delta1 dihydropyridine receptor subunit is a critical element for excitation-coupled calcium entry but not for formation of tetrads in skeletal myotubes.
PubMed Identifier: 18192372
author list: Gach MP, Cherednichenko G, Haarmann C, Lopez JR, Beam KG, Pessah IN, Franzini-Armstrong C, Allen PD
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information resource reference: Alpha2delta1 dihydropyridine receptor subunit is a critical element for excitation-coupled calcium entry but not for formation of tetrads in skeletal myotubes. Biophys J. 2008 Apr 15; 94(8):3023-34.
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Troponin I phosphorylation in the normal and failing adult human heart.
PubMed Identifier: 9315537
author list: Bodor GS, Oakeley AE, Allen PD, Crimmins DL, Ladenson JH, Anderson PA
published in: Circulation
information resource reference: Troponin I phosphorylation in the normal and failing adult human heart. Circulation. 1997 Sep 02; 96(5):1495-500.
journal title abbreviation: Circulation
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A transgenic myogenic cell line lacking ryanodine receptor protein for homologous expression studies: reconstitution of Ry1R protein and function.
PubMed Identifier: 9472036
author list: Moore RA, Nguyen H, Galceran J, Pessah IN, Allen PD
published in: The Journal of cell biology
information resource reference: A transgenic myogenic cell line lacking ryanodine receptor protein for homologous expression studies: reconstitution of Ry1R protein and function. J Cell Biol. 1998 Feb 23; 140(4):843-51.
journal title abbreviation: J Cell Biol
publication date: 1998-02-23T00:00:00
year: 1998
type: Academic Article
type: Article
type: Document
type: Information Resource

Troponin T isoform expression in the normal and failing human left ventricle: a correlation with myofibrillar ATPase activity.
PubMed Identifier: 1386729
author list: Anderson PA, Malouf NN, Oakeley AE, Pagani ED, Allen PD
published in: Basic research in cardiology
information resource reference: Troponin T isoform expression in the normal and failing human left ventricle: a correlation with myofibrillar ATPase activity. Basic Res Cardiol. 1992; 87 Suppl 1:117-27.
journal title abbreviation: Basic Res Cardiol
publication date: 1992-01-01T00:00:00
year: 1992
type: Academic Article
type: Article
type: Document
type: Information Resource

Effects of milrinone on Ca++-sensitivity of myofibrillar Mg-adenosine triphosphatase isolated from normal human and canine hearts.
PubMed Identifier: 2969049
author list: Alousi AA, Grant AM, Allen PD, Pagani ED
published in: The Journal of pharmacology and experimental therapeutics
information resource reference: Effects of milrinone on Ca++-sensitivity of myofibrillar Mg-adenosine triphosphatase isolated from normal human and canine hearts. J Pharmacol Exp Ther. 1988 Jul; 246(1):30-7.
journal title abbreviation: J Pharmacol Exp Ther
publication date: 1988-07-01T00:00:00
year: 1988
type: Academic Article
type: Article
type: Document
type: Information Resource

Comparison of contractile state and myosin isozymes of rat right and left ventricular myocardium.
PubMed Identifier: 3625780
author list: Brooks WW, Bing OH, Blaustein AS, Allen PD
published in: Journal of molecular and cellular cardiology
information resource reference: Comparison of contractile state and myosin isozymes of rat right and left ventricular myocardium. J Mol Cell Cardiol. 1987 May; 19(5):433-40.
journal title abbreviation: J Mol Cell Cardiol
publication date: 1987-05-01T00:00:00
year: 1987
type: Academic Article
type: Article
type: Document
type: Information Resource

Hypersensitivity of malignant hyperthermia-susceptible swine skeletal muscle to caffeine is mediated by high resting myoplasmic [Ca2+ ].
PubMed Identifier: 10839932
author list: López JR, Contreras J, Linares N, Allen PD
published in: Anesthesiology
information resource reference: Hypersensitivity of malignant hyperthermia-susceptible swine skeletal muscle to caffeine is mediated by high resting myoplasmic [Ca2+ ]. Anesthesiology. 2000 Jun; 92(6):1799-806.
journal title abbreviation: Anesthesiology
publication date: 2000-06-01T00:00:00
year: 2000
type: Academic Article
type: Article
type: Document
type: Information Resource

Ca2+ activation of RyR1 is not necessary for the initiation of skeletal-type excitation-contraction coupling.
PubMed Identifier: 11964231
author list: O'Brien JJ, Feng W, Allen PD, Chen SR, Pessah IN, Beam KG
published in: Biophysical journal
information resource reference: Ca2+ activation of RyR1 is not necessary for the initiation of skeletal-type excitation-contraction coupling. Biophys J. 2002 May; 82(5):2428-35.
journal title abbreviation: Biophys J
publication date: 2002-05-01T00:00:00
year: 2002
type: Academic Article
type: Article
type: Document
type: Information Resource

Acute appendicitis in children; a review of 1,165 cases.
PubMed Identifier: 14790580
author list: ABEL WG, ALLEN PD
published in: Annals of surgery
information resource reference: Acute appendicitis in children; a review of 1,165 cases. Ann Surg. 1950 Dec; 132(6):1093-1102.
journal title abbreviation: Ann Surg
publication date: 1950-12-01T00:00:00
year: 1950
type: Academic Article
type: Article
type: Document
type: Information Resource

Functional coupling between TRPC3 and RyR1 regulates the expressions of key triadic proteins.
PubMed Identifier: 16484216
author list: Lee EH, Cherednichenko G, Pessah IN, Allen PD
published in: The Journal of biological chemistry
information resource reference: Functional coupling between TRPC3 and RyR1 regulates the expressions of key triadic proteins. J Biol Chem. 2006 Apr 14; 281(15):10042-8.
journal title abbreviation: J Biol Chem
publication date: 2006-02-16T00:00:00
year: 2006
type: Academic Article
type: Article
type: Document
type: Information Resource

Herpes simplex virus type 1 amplicon vector-mediated gene transfer to muscle.
PubMed Identifier: 11812282
author list: Wang Y, Mukherjee S, Fraefel C, Breakefield XO, Allen PD
published in: Human gene therapy
information resource reference: Herpes simplex virus type 1 amplicon vector-mediated gene transfer to muscle. Hum Gene Ther. 2002 Jan 20; 13(2):261-73.
journal title abbreviation: Hum Gene Ther
publication date: 2002-01-20T00:00:00
year: 2002
type: Academic Article
type: Article
type: Document
type: Information Resource

The creatine kinase system in normal and diseased human myocardium.
PubMed Identifier: 2931604
author list: Ingwall JS, Kramer MF, Fifer MA, Lorell BH, Shemin R, Grossman W, Allen PD
published in: The New England journal of medicine
information resource reference: The creatine kinase system in normal and diseased human myocardium. N Engl J Med. 1985 Oct 24; 313(17):1050-4.
journal title abbreviation: N Engl J Med
publication date: 1985-10-24T00:00:00
year: 1985
type: Academic Article
type: Article
type: Document
type: Information Resource

Conformational activation of Ca2+ entry by depolarization of skeletal myotubes.
PubMed Identifier: 15505226
author list: Cherednichenko G, Hurne AM, Fessenden JD, Lee EH, Allen PD, Beam KG, Pessah IN
published in: Proceedings of the National Academy of Sciences of the United States of America
information resource reference: Conformational activation of Ca2+ entry by depolarization of skeletal myotubes. Proc Natl Acad Sci U S A. 2004 Nov 02; 101(44):15793-8.
journal title abbreviation: Proc Natl Acad Sci U S A
publication date: 2004-10-25T00:00:00
year: 2004
type: Academic Article
type: Article
type: Document
type: Information Resource

Ryanodine receptor type 1 (RyR1) mutations C4958S and C4961S reveal excitation-coupled calcium entry (ECCE) is independent of sarcoplasmic reticulum store depletion.
PubMed Identifier: 16120606
author list: Hurne AM, O'Brien JJ, Wingrove D, Cherednichenko G, Allen PD, Beam KG, Pessah IN
published in: The Journal of biological chemistry
information resource reference: Ryanodine receptor type 1 (RyR1) mutations C4958S and C4961S reveal excitation-coupled calcium entry (ECCE) is independent of sarcoplasmic reticulum store depletion. J Biol Chem. 2005 Nov 04; 280(44):36994-7004.
journal title abbreviation: J Biol Chem
publication date: 2005-08-24T00:00:00
year: 2005
type: Academic Article
type: Article
type: Document
type: Information Resource

Structural characterization of the RyR1-FKBP12 interaction.
PubMed Identifier: 16405911
author list: Samsó M, Shen X, Allen PD
published in: Journal of molecular biology
information resource reference: Structural characterization of the RyR1-FKBP12 interaction. J Mol Biol. 2006 Mar 03; 356(4):917-27.
journal title abbreviation: J Mol Biol
publication date: 2005-12-27T00:00:00
year: 2005
type: Academic Article
type: Article
type: Document
type: Information Resource

Skeletal actin mRNA increases in the human heart during ontogenic development and is the major isoform of control and failing adult hearts.
PubMed Identifier: 2056125
author list: Boheler KR, Carrier L, de la Bastie D, Allen PD, Komajda M, Mercadier JJ, Schwartz K
published in: The Journal of clinical investigation
information resource reference: Skeletal actin mRNA increases in the human heart during ontogenic development and is the major isoform of control and failing adult hearts. J Clin Invest. 1991 Jul; 88(1):323-30.
journal title abbreviation: J Clin Invest
publication date: 1991-07-01T00:00:00
year: 1991
type: Academic Article
type: Article
type: Document
type: Information Resource

Conformation-dependent stability of junctophilin 1 (JP1) and ryanodine receptor type 1 (RyR1) channel complex is mediated by their hyper-reactive thiols.
PubMed Identifier: 17237236
author list: Phimister AJ, Lango J, Lee EH, Ernst-Russell MA, Takeshima H, Ma J, Allen PD, Pessah IN
published in: The Journal of biological chemistry
information resource reference: Conformation-dependent stability of junctophilin 1 (JP1) and ryanodine receptor type 1 (RyR1) channel complex is mediated by their hyper-reactive thiols. J Biol Chem. 2007 Mar 23; 282(12):8667-77.
journal title abbreviation: J Biol Chem
publication date: 2007-01-19T00:00:00
year: 2007
type: Academic Article
type: Article
type: Document
type: Information Resource

RyR1-specific requirement for depolarization-induced Ca2+ sparks in urinary bladder smooth muscle.
PubMed Identifier: 17925380
author list: Fritz N, Morel JL, Jeyakumar LH, Fleischer S, Allen PD, Mironneau J, Macrez N
published in: Journal of cell science
information resource reference: RyR1-specific requirement for depolarization-induced Ca2+ sparks in urinary bladder smooth muscle. J Cell Sci. 2007 Nov 01; 120(Pt 21):3784-91.
journal title abbreviation: J Cell Sci
publication date: 2007-10-09T00:00:00
year: 2007
type: Academic Article
type: Article
type: Document
type: Information Resource

Conformational coupling of DHPR and RyR1 in skeletal myotubes is influenced by long-range allosterism: evidence for a negative regulatory module.
PubMed Identifier: 13679303
author list: Lee EH, Lopez JR, Li J, Protasi F, Pessah IN, Kim DH, Allen PD
published in: American journal of physiology. Cell physiology
information resource reference: Conformational coupling of DHPR and RyR1 in skeletal myotubes is influenced by long-range allosterism: evidence for a negative regulatory module. Am J Physiol Cell Physiol. 2004 Jan; 286(1):C179-89.
journal title abbreviation: Am J Physiol Cell Physiol
publication date: 2003-09-17T00:00:00
year: 2003
type: Academic Article
type: Article
type: Document
type: Information Resource

Enhanced response to caffeine and 4-chloro-m-cresol in malignant hyperthermia-susceptible muscle is related in part to chronically elevated resting [Ca2+]i.
PubMed Identifier: 15537710
author list: López JR, Linares N, Pessah IN, Allen PD
published in: American journal of physiology. Cell physiology
information resource reference: Enhanced response to caffeine and 4-chloro-m-cresol in malignant hyperthermia-susceptible muscle is related in part to chronically elevated resting [Ca2+]i. Am J Physiol Cell Physiol. 2005 Mar; 288(3):C606-12.
journal title abbreviation: Am J Physiol Cell Physiol
publication date: 2004-11-10T00:00:00
year: 2004
type: Academic Article
type: Article
type: Document
type: Information Resource

Dynamic regulation of ryanodine receptor type 1 (RyR1) channel activity by Homer 1.
PubMed Identifier: 17707505
author list: Feng W, Tu J, Pouliquin P, Cabrales E, Shen X, Dulhunty A, Worley PF, Allen PD, Pessah IN
published in: Cell calcium
information resource reference: Dynamic regulation of ryanodine receptor type 1 (RyR1) channel activity by Homer 1. Cell Calcium. 2008 Mar; 43(3):307-14.
journal title abbreviation: Cell Calcium
publication date: 2007-08-17T00:00:00
year: 2007
type: Academic Article
type: Article
type: Document
type: Information Resource

Developmental regulation of cardiac calcium channels and contractile sensitivity to [Ca]o.
PubMed Identifier: 2463772
author list: Marsh JD, Allen PD
published in: The American journal of physiology
information resource reference: Developmental regulation of cardiac calcium channels and contractile sensitivity to [Ca]o. Am J Physiol. 1989 Jan; 256(1 Pt 2):H179-85.
journal title abbreviation: Am J Physiol
publication date: 1989-01-01T00:00:00
year: 1989
type: Academic Article
type: Article
type: Document
type: Information Resource

Triadin/Junctin double null mouse reveals a differential role for Triadin and Junctin in anchoring CASQ to the jSR and regulating Ca(2+) homeostasis.
PubMed Identifier: 22768324
author list: Boncompagni S, Thomas M, Lopez JR, Allen PD, Yuan Q, Kranias EG, Franzini-Armstrong C, Perez CF
published in: PloS one
information resource reference: Triadin/Junctin double null mouse reveals a differential role for Triadin and Junctin in anchoring CASQ to the jSR and regulating Ca(2+) homeostasis. PLoS One. 2012; 7(7):e39962.
journal title abbreviation: PLoS One
publication date: 2012-07-02T00:00:00
year: 2012
type: Academic Article
type: Article
type: Document
type: Information Resource

Presbycusis phenotypes form a heterogeneous continuum when ordered by degree and configuration of hearing loss.
PubMed Identifier: 20144701
author list: Allen PD, Eddins DA
published in: Hearing research
information resource reference: Presbycusis phenotypes form a heterogeneous continuum when ordered by degree and configuration of hearing loss. Hear Res. 2010 Jun 01; 264(1-2):10-20.
journal title abbreviation: Hear Res
publication date: 2010-02-06T00:00:00
year: 2010
type: Academic Article
type: Article
type: Document
type: Information Resource

Perceived exertion associated with breathing hyperoxic mixtures during submaximal work.
PubMed Identifier: 895429
author list: Allen PD, Pandolf KB
published in: Medicine and science in sports
information resource reference: Perceived exertion associated with breathing hyperoxic mixtures during submaximal work. Med Sci Sports. 1977; 9(2):122-7.
journal title abbreviation: Med Sci Sports
publication date: 1977-01-01T00:00:00
year: 1977
type: Academic Article
type: Article
type: Document
type: Information Resource

Green tea catechins are potent sensitizers of ryanodine receptor type 1 (RyR1).
PubMed Identifier: 20471964
author list: Feng W, Cherednichenko G, Ward CW, Padilla IT, Cabrales E, Lopez JR, Eltit JM, Allen PD, Pessah IN
published in: Biochemical pharmacology
information resource reference: Green tea catechins are potent sensitizers of ryanodine receptor type 1 (RyR1). Biochem Pharmacol. 2010 Aug 15; 80(4):512-21.
journal title abbreviation: Biochem Pharmacol
publication date: 2010-05-22T00:00:00
year: 2010
type: Academic Article
type: Article
type: Document
type: Information Resource

Calcium transients in 1B5 myotubes lacking ryanodine receptors are related to inositol trisphosphate receptors.
PubMed Identifier: 11301324
author list: Estrada M, Cárdenas C, Liberona JL, Carrasco MA, Mignery GA, Allen PD, Jaimovich E
published in: The Journal of biological chemistry
information resource reference: Calcium transients in 1B5 myotubes lacking ryanodine receptors are related to inositol trisphosphate receptors. J Biol Chem. 2001 Jun 22; 276(25):22868-74.
journal title abbreviation: J Biol Chem
publication date: 2001-04-11T00:00:00
year: 2001
type: Academic Article
type: Article
type: Document
type: Information Resource

Leaky "feet" and sudden death.
PubMed Identifier: 12169641
author list: Allen PD
published in: Circulation research
information resource reference: Leaky "feet" and sudden death. Circ Res. 2002 Aug 09; 91(3):181-2.
journal title abbreviation: Circ Res
publication date: 2002-08-09T00:00:00
year: 2002
type: Academic Article
type: Article
type: Document
type: Information Resource

Contractile impairment and structural alterations of skeletal muscles from knockout mice lacking type 1 and type 3 ryanodine receptors.
PubMed Identifier: 9489997
author list: Barone V, Bertocchini F, Bottinelli R, Protasi F, Allen PD, Franzini Armstrong C, Reggiani C, Sorrentino V
published in: FEBS letters
information resource reference: Contractile impairment and structural alterations of skeletal muscles from knockout mice lacking type 1 and type 3 ryanodine receptors. FEBS Lett. 1998 Jan 30; 422(2):160-4.
journal title abbreviation: FEBS Lett
publication date: 1998-01-30T00:00:00
year: 1998
type: Academic Article
type: Article
type: Document
type: Information Resource

Amino acid residues Gln4020 and Lys4021 of the ryanodine receptor type 1 are required for activation by 4-chloro-m-cresol.
PubMed Identifier: 16737973
author list: Fessenden JD, Feng W, Pessah IN, Allen PD
published in: The Journal of biological chemistry
information resource reference: Amino acid residues Gln4020 and Lys4021 of the ryanodine receptor type 1 are required for activation by 4-chloro-m-cresol. J Biol Chem. 2006 Jul 28; 281(30):21022-21031.
journal title abbreviation: J Biol Chem
publication date: 2006-05-31T00:00:00
year: 2006
type: Academic Article
type: Article
type: Document
type: Information Resource

Multiple regions of RyR1 mediate functional and structural interactions with alpha(1S)-dihydropyridine receptors in skeletal muscle.
PubMed Identifier: 12496092
author list: Protasi F, Paolini C, Nakai J, Beam KG, Franzini-Armstrong C, Allen PD
published in: Biophysical journal
information resource reference: Multiple regions of RyR1 mediate functional and structural interactions with alpha(1S)-dihydropyridine receptors in skeletal muscle. Biophys J. 2002 Dec; 83(6):3230-44.
journal title abbreviation: Biophys J
publication date: 2002-12-01T00:00:00
year: 2002
type: Academic Article
type: Article
type: Document
type: Information Resource

Autotransplantation in mdx mice of mdx myoblasts genetically corrected by an HSV-1 amplicon vector.
PubMed Identifier: 12588108
author list: Bujold M, Caron N, Camiran G, Mukherjee S, Allen PD, Tremblay JP, Wang Y
published in: Cell transplantation
information resource reference: Autotransplantation in mdx mice of mdx myoblasts genetically corrected by an HSV-1 amplicon vector. Cell Transplant. 2002; 11(8):759-67.
journal title abbreviation: Cell Transplant
publication date: 2002-01-01T00:00:00
year: 2002
type: Academic Article
type: Article
type: Document
type: Information Resource

Two regions of the ryanodine receptor involved in coupling with L-type Ca2+ channels.
PubMed Identifier: 9593671
author list: Nakai J, Sekiguchi N, Rando TA, Allen PD, Beam KG
published in: The Journal of biological chemistry
information resource reference: Two regions of the ryanodine receptor involved in coupling with L-type Ca2+ channels. J Biol Chem. 1998 May 29; 273(22):13403-6.
journal title abbreviation: J Biol Chem
publication date: 1998-05-29T00:00:00
year: 1998
type: Academic Article
type: Article
type: Document
type: Information Resource