Van Allen, Eliezer
completed student projects: Dissecting Genomic Determinants of Response to Platinum-based Chemotherapy in Advanced NSCLC and Colorectal Cancer
completed student projects: Genomic predictors of response to CTLA4 blockade in metastatic melanoma
completed student projects: Intron retention as a novel source of tumor neoantigens associated with response to checkpoint inhibitor therapy
completed student projects: Transcriptomic Correlates of Response to Immune Checkpoint Therapies in Melanoma
completed student projects: Expanding accessibility of a molecular oncology almanac for precision cancer medicine
eCommons Login: EMV7
first name: Eliezer
last name: Van Allen
coauthor of: Choueiri, Toni
coauthor of: Gillani, Riaz
coauthor of: Aldubayan, Saud
coauthor of: Pimenta, Erica
coauthor of: Liu, David
full name: Eliezer Mendel Van Allen, M.D.
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Authorship 1045571
type: Authorship
author rank in publication: 16
linked author: Van Allen, Eliezer
linked information resource: Inherited DNA-Repair Defects in Colorectal Cancer.

Authorship 1046280
type: Authorship
author rank in publication: 22
linked author: Van Allen, Eliezer
linked information resource: Convergent Therapeutic Strategies to Overcome the Heterogeneity of Acquired Resistance in BRAFV600E Colorectal Cancer.

Inherited DNA-Repair Defects in Colorectal Cancer.
PubMed Identifier: 29478780
author list: AlDubayan SH, Giannakis M, Moore ND, Han GC, Reardon B, Hamada T, Mu XJ, Nishihara R, Qian Z, Liu L, Yurgelun MB, Syngal S, Garraway LA, Ogino S, Fuchs CS, Van Allen EM
published in: American journal of human genetics
information resource reference: Inherited DNA-Repair Defects in Colorectal Cancer. Am J Hum Genet. 2018 03 01; 102(3):401-414.
journal title abbreviation: Am J Hum Genet
publication date: 2018-02-22T00:00:00
year: 2018
type: Academic Article
type: Article
type: Document
type: Information Resource

Convergent Therapeutic Strategies to Overcome the Heterogeneity of Acquired Resistance in BRAFV600E Colorectal Cancer.
PubMed Identifier: 29431697
author list: Hazar-Rethinam M, Kleyman M, Han GC, Liu D, Ahronian LG, Shahzade HA, Chen L, Parikh AR, Allen JN, Clark JW, Kwak EL, Faris JE, Murphy JE, Hong TS, Van Seventer EE, Nadres B, Hong CB, Gurski JM, Jessop NA, Dias-Santagata D, Iafrate AJ, Van Allen EM, Corcoran RB
published in: Cancer discovery
information resource reference: Convergent Therapeutic Strategies to Overcome the Heterogeneity of Acquired Resistance in BRAFV600E Colorectal Cancer. Cancer Discov. 2018 04; 8(4):417-427.
journal title abbreviation: Cancer Discov
publication date: 2018-02-05T00:00:00
year: 2018
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1055226
type: Authorship
author rank in publication: 6
linked author: Van Allen, Eliezer
linked information resource: Phase I Trial of a Tablet Formulation of Pilaralisib, a Pan-Class I PI3K Inhibitor, in Patients with Advanced Solid Tumors.

Phase I Trial of a Tablet Formulation of Pilaralisib, a Pan-Class I PI3K Inhibitor, in Patients with Advanced Solid Tumors.
PubMed Identifier: 29593099
author list: Edelman G, Rodon J, Lager J, Castell C, Jiang J, Van Allen EM, Wagle N, Lindeman NI, Sholl LM, Shapiro GI
published in: The oncologist
information resource reference: Phase I Trial of a Tablet Formulation of Pilaralisib, a Pan-Class I PI3K Inhibitor, in Patients with Advanced Solid Tumors. Oncologist. 2018 04; 23(4):401-e38.
journal title abbreviation: Oncologist
publication date: 2018-03-28T00:00:00
year: 2018
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1055906
type: Authorship
author rank in publication: 40
linked author: Van Allen, Eliezer
linked information resource: The long tail of oncogenic drivers in prostate cancer.

The long tail of oncogenic drivers in prostate cancer.
PubMed Identifier: 29610475
author list: Armenia J, Wankowicz SAM, Liu D, Gao J, Kundra R, Reznik E, Chatila WK, Chakravarty D, Han GC, Coleman I, Montgomery B, Pritchard C, Morrissey C, Barbieri CE, Beltran H, Sboner A, Zafeiriou Z, Miranda S, Bielski CM, Penson AV, Tolonen C, Huang FW, Robinson D, Wu YM, Lonigro R, Garraway LA, Demichelis F, Kantoff PW, Taplin ME, Abida W, Taylor BS, Scher HI, Nelson PS, de Bono JS, Rubin MA, Sawyers CL, Chinnaiyan AM, Schultz N, Van Allen EM
published in: Nature genetics
information resource reference: The long tail of oncogenic drivers in prostate cancer. Nat Genet. 2018 05; 50(5):645-651.
journal title abbreviation: Nat Genet
publication date: 2018-04-02T00:00:00
year: 2018
type: Academic Article
type: Article
type: Document
type: Information Resource

Cancer-Germline Antigen Expression Discriminates Clinical Outcome to CTLA-4 Blockade.
PubMed Identifier: 29656892
author list: Shukla SA, Bachireddy P, Schilling B, Galonska C, Zhan Q, Bango C, Langer R, Lee PC, Gusenleitner D, Keskin DB, Babadi M, Mohammad A, Gnirke A, Clement K, Cartun ZJ, Van Allen EM, Miao D, Huang Y, Snyder A, Merghoub T, Wolchok JD, Garraway LA, Meissner A, Weber JS, Hacohen N, Neuberg D, Potts PR, Murphy GF, Lian CG, Schadendorf D, Hodi FS, Wu CJ
published in: Cell
information resource reference: Cancer-Germline Antigen Expression Discriminates Clinical Outcome to CTLA-4 Blockade. Cell. 2018 04 19; 173(3):624-633.e8.
journal title abbreviation: Cell
publication date: 2018-04-12T00:00:00
year: 2018
type: Academic Article
type: Article
type: Document
type: Information Resource

One day later. Continuing psychological stress after a cardiac intensive care rotation.
PubMed Identifier: 20414737
author list: Van Allen EM
published in: Journal of general internal medicine
information resource reference: One day later. Continuing psychological stress after a cardiac intensive care rotation. J Gen Intern Med. 2010 Aug; 25(8):882-3.
journal title abbreviation: J Gen Intern Med
publication date: 2010-08-01T00:00:00
year: 2010
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1057481
type: Authorship
author rank in publication: 33
linked author: Van Allen, Eliezer
linked information resource: Comprehensive Characterization of Cancer Driver Genes and Mutations.

Authorship 1057621
type: Authorship
author rank in publication: 51
linked author: Van Allen, Eliezer
linked information resource: Oncogenic Signaling Pathways in The Cancer Genome Atlas.

Authorship 1058309
type: Authorship
author rank in publication: 16
linked author: Van Allen, Eliezer
linked information resource: Cancer-Germline Antigen Expression Discriminates Clinical Outcome to CTLA-4 Blockade.

Oncogenic Signaling Pathways in The Cancer Genome Atlas.
PubMed Identifier: 29625050
author list: Sanchez-Vega F, Mina M, Armenia J, Chatila WK, Luna A, La KC, Dimitriadoy S, Liu DL, Kantheti HS, Saghafinia S, Chakravarty D, Daian F, Gao Q, Bailey MH, Liang WW, Foltz SM, Shmulevich I, Ding L, Heins Z, Ochoa A, Gross B, Gao J, Zhang H, Kundra R, Kandoth C, Bahceci I, Dervishi L, Dogrusoz U, Zhou W, Shen H, Laird PW, Way GP, Greene CS, Liang H, Xiao Y, Wang C, Iavarone A, Berger AH, Bivona TG, Lazar AJ, Hammer GD, Giordano T, Kwong LN, McArthur G, Huang C, Tward AD, Frederick MJ, McCormick F, Meyerson M, Van Allen EM, Cherniack AD, Ciriello G, Sander C, Schultz N
published in: Cell
information resource reference: Oncogenic Signaling Pathways in The Cancer Genome Atlas. Cell. 2018 04 05; 173(2):321-337.e10.
journal title abbreviation: Cell
publication date: 2018-04-05T00:00:00
year: 2018
type: Academic Article
type: Article
type: Document
type: Information Resource

Comprehensive Characterization of Cancer Driver Genes and Mutations.
PubMed Identifier: 29625053
author list: Bailey MH, Tokheim C, Porta-Pardo E, Sengupta S, Bertrand D, Weerasinghe A, Colaprico A, Wendl MC, Kim J, Reardon B, Ng PK, Jeong KJ, Cao S, Wang Z, Gao J, Gao Q, Wang F, Liu EM, Mularoni L, Rubio-Perez C, Nagarajan N, Cortés-Ciriano I, Zhou DC, Liang WW, Hess JM, Yellapantula VD, Tamborero D, Gonzalez-Perez A, Suphavilai C, Ko JY, Khurana E, Park PJ, Van Allen EM, Liang H, Lawrence MS, Godzik A, Lopez-Bigas N, Stuart J, Wheeler D, Getz G, Chen K, Lazar AJ, Mills GB, Karchin R, Ding L
published in: Cell
information resource reference: Comprehensive Characterization of Cancer Driver Genes and Mutations. Cell. 2018 04 05; 173(2):371-385.e18.
journal title abbreviation: Cell
publication date: 2018-04-05T00:00:00
year: 2018
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1061157
type: Authorship
author rank in publication: 18
linked author: Van Allen, Eliezer
linked information resource: Whole-exome sequencing of cell-free DNA and circulating tumor cells in multiple myeloma.

Whole-exome sequencing of cell-free DNA and circulating tumor cells in multiple myeloma.
PubMed Identifier: 29703982
author list: Manier S, Park J, Capelletti M, Bustoros M, Freeman SS, Ha G, Rhoades J, Liu CJ, Huynh D, Reed SC, Gydush G, Salem KZ, Rotem D, Freymond C, Yosef A, Perilla-Glen A, Garderet L, Van Allen EM, Kumar S, Love JC, Getz G, Adalsteinsson VA, Ghobrial IM
published in: Nature communications
information resource reference: Whole-exome sequencing of cell-free DNA and circulating tumor cells in multiple myeloma. Nat Commun. 2018 04 27; 9(1):1691.
journal title abbreviation: Nat Commun
publication date: 2018-04-27T00:00:00
year: 2018
type: Academic Article
type: Article
type: Document
type: Information Resource

Dissecting Genomic Determinants of Response to Platinum-based Chemotherapy in Advanced NSCLC and Colorectal Cancer
end date: 2017-12-31T00:00:00
start date: 2017-01-01T00:00:00
type: Mentoring - Completed Student Project
overview: Part Time

The Clinical Activity of PD-1/PD-L1 Inhibitors in Metastatic Non-Clear Cell Renal Cell Carcinoma.
PubMed Identifier: 29748390
author list: McKay RR, Bossé D, Xie W, Wankowicz SAM, Flaifel A, Brandao R, Lalani AA, Martini DJ, Wei XX, Braun DA, Van Allen E, Castellano D, De Velasco G, Wells JC, Heng DY, Fay AP, Schutz FA, Hsu J, Pal SK, Lee JL, Hsieh JJ, Harshman LC, Signoretti S, Motzer RJ, Feldman D, Choueiri TK
published in: Cancer immunology research
information resource reference: The Clinical Activity of PD-1/PD-L1 Inhibitors in Metastatic Non-Clear Cell Renal Cell Carcinoma. Cancer Immunol Res. 2018 07; 6(7):758-765.
journal title abbreviation: Cancer Immunol Res
publication date: 2018-05-10T00:00:00
year: 2018
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1066293
type: Authorship
author rank in publication: 11
linked author: Van Allen, Eliezer
linked information resource: The Clinical Activity of PD-1/PD-L1 Inhibitors in Metastatic Non-Clear Cell Renal Cell Carcinoma.

Integrative Somatic and Germline Computational Biology to Redefine Clinical Actionability in Solid Tumors
end date: 2023-05-31
principal investigator name: VAN ALLEN, ELIEZER M
start date: 2018-06-01
type: Grant
sponsor award id: R01CA227388

Principal Investigator
type: Researcher Role
researcher role of: Van Allen, Eliezer
contributes to: Integrative Somatic and Germline Computational Biology to Redefine Clinical Actionability in Solid Tumors

Authorship 1074208
type: Authorship
author rank in publication: 26
linked author: Van Allen, Eliezer
linked information resource: Structural Alterations Driving Castration-Resistant Prostate Cancer Revealed by Linked-Read Genome Sequencing.

Authorship 1073227
type: Authorship
author rank in publication: 10
linked author: Van Allen, Eliezer
linked information resource: Integrated genomic characterization of oral carcinomas in post-hematopoietic stem cell transplantation survivors.

Authorship 1073851
type: Authorship
author rank in publication: 4
linked author: Van Allen, Eliezer
linked information resource: Neoadjuvant-Intensive Androgen Deprivation Therapy Selects for Prostate Tumor Foci with Diverse Subclonal Oncogenic Alterations.

Authorship 1074477
type: Authorship
author rank in publication: 10
linked author: Van Allen, Eliezer
linked information resource: Early loss of mitochondrial complex I and rewiring of glutathione metabolism in renal oncocytoma.

Neoadjuvant-Intensive Androgen Deprivation Therapy Selects for Prostate Tumor Foci with Diverse Subclonal Oncogenic Alterations.
PubMed Identifier: 29921690
author list: Sowalsky AG, Ye H, Bhasin M, Van Allen EM, Loda M, Lis RT, Montaser-Kouhsari L, Calagua C, Ma F, Russo JW, Schaefer RJ, Voznesensky OS, Zhang Z, Bubley GJ, Montgomery B, Mostaghel EA, Nelson PS, Taplin ME, Balk SP
published in: Cancer research
information resource reference: Neoadjuvant-Intensive Androgen Deprivation Therapy Selects for Prostate Tumor Foci with Diverse Subclonal Oncogenic Alterations. Cancer Res. 2018 08 15; 78(16):4716-4730.
journal title abbreviation: Cancer Res
publication date: 2018-06-19T00:00:00
year: 2018
type: Academic Article
type: Article
type: Document
type: Information Resource

Early loss of mitochondrial complex I and rewiring of glutathione metabolism in renal oncocytoma.
PubMed Identifier: 29915083
author list: Gopal RK, Calvo SE, Shih AR, Chaves FL, McGuone D, Mick E, Pierce KA, Li Y, Garofalo A, Van Allen EM, Clish CB, Oliva E, Mootha VK
published in: Proceedings of the National Academy of Sciences of the United States of America
information resource reference: Early loss of mitochondrial complex I and rewiring of glutathione metabolism in renal oncocytoma. Proc Natl Acad Sci U S A. 2018 07 03; 115(27):E6283-E6290.
journal title abbreviation: Proc Natl Acad Sci U S A
publication date: 2018-06-18T00:00:00
year: 2018
type: Academic Article
type: Article
type: Document
type: Information Resource

Integrated genomic characterization of oral carcinomas in post-hematopoietic stem cell transplantation survivors.
PubMed Identifier: 29884406
author list: Hanna GJ, Kofman ER, Shazib MA, Woo SB, Reardon B, Treister NS, Haddad RI, Cutler CS, Antin JH, Van Allen EM, Uppaluri R, Soiffer RJ
published in: Oral oncology
information resource reference: Integrated genomic characterization of oral carcinomas in post-hematopoietic stem cell transplantation survivors. Oral Oncol. 2018 06; 81:1-9.
journal title abbreviation: Oral Oncol
publication date: 2018-04-10T00:00:00
year: 2018
type: Academic Article
type: Article
type: Document
type: Information Resource

Structural Alterations Driving Castration-Resistant Prostate Cancer Revealed by Linked-Read Genome Sequencing.
PubMed Identifier: 29909985
author list: Viswanathan SR, Ha G, Hoff AM, Wala JA, Carrot-Zhang J, Whelan CW, Haradhvala NJ, Freeman SS, Reed SC, Rhoades J, Polak P, Cipicchio M, Wankowicz SA, Wong A, Kamath T, Zhang Z, Gydush GJ, Rotem D, Love JC, Getz G, Gabriel S, Zhang CZ, Dehm SM, Nelson PS, Van Allen EM, Choudhury AD, Adalsteinsson VA, Beroukhim R, Taplin ME, Meyerson M
published in: Cell
information resource reference: Structural Alterations Driving Castration-Resistant Prostate Cancer Revealed by Linked-Read Genome Sequencing. Cell. 2018 07 12; 174(2):433-447.e19.
journal title abbreviation: Cell
publication date: 2018-06-18T00:00:00
year: 2018
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1077119
type: Authorship
author rank in publication: 11
linked author: Van Allen, Eliezer
linked information resource: LSD1 Ablation Stimulates Anti-tumor Immunity and Enables Checkpoint Blockade.

LSD1 Ablation Stimulates Anti-tumor Immunity and Enables Checkpoint Blockade.
PubMed Identifier: 29937226
author list: Sheng W, LaFleur MW, Nguyen TH, Chen S, Chakravarthy A, Conway JR, Li Y, Chen H, Yang H, Hsu PH, Van Allen EM, Freeman GJ, De Carvalho DD, He HH, Sharpe AH, Shi Y
published in: Cell
information resource reference: LSD1 Ablation Stimulates Anti-tumor Immunity and Enables Checkpoint Blockade. Cell. 2018 07 26; 174(3):549-563.e19.
journal title abbreviation: Cell
publication date: 2018-06-21T00:00:00
year: 2018
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1077659
type: Authorship
author rank in publication: 21
linked author: Van Allen, Eliezer
linked information resource: ERCC2 Helicase Domain Mutations Confer Nucleotide Excision Repair Deficiency and Drive Cisplatin Sensitivity in Muscle-Invasive Bladder Cancer.

ERCC2 Helicase Domain Mutations Confer Nucleotide Excision Repair Deficiency and Drive Cisplatin Sensitivity in Muscle-Invasive Bladder Cancer.
PubMed Identifier: 29980530
author list: Li Q, Damish AW, Frazier Z, Liu D, Reznichenko E, Kamburov A, Bell A, Zhao H, Jordan EJ, Gao SP, Ma J, Abbosh PH, Bellmunt J, Plimack ER, Lazaro JB, Solit DB, Bajorin D, Rosenberg JE, D'Andrea AD, Riaz N, Van Allen EM, Iyer G, Mouw KW
published in: Clinical cancer research : an official journal of the American Association for Cancer Research
information resource reference: ERCC2 Helicase Domain Mutations Confer Nucleotide Excision Repair Deficiency and Drive Cisplatin Sensitivity in Muscle-Invasive Bladder Cancer. Clin Cancer Res. 2019 02 01; 25(3):977-988.
journal title abbreviation: Clin Cancer Res
publication date: 2018-07-06T00:00:00
year: 2018
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1082783
type: Authorship
author rank in publication: 9
linked author: Van Allen, Eliezer
linked information resource: Detection of Somatic Structural Variants Enables Quantification and Characterization of Circulating Tumor DNA in Children With Solid Tumors.

Detection of Somatic Structural Variants Enables Quantification and Characterization of Circulating Tumor DNA in Children With Solid Tumors.
PubMed Identifier: 30027144
author list: Klega K, Imamovic-Tuco A, Ha G, Clapp AN, Meyer S, Ward A, Clinton C, Nag A, Van Allen E, Mullen E, DuBois SG, Janeway K, Meyerson M, Thorner AR, Crompton BD
published in: JCO precision oncology
information resource reference: Detection of Somatic Structural Variants Enables Quantification and Characterization of Circulating Tumor DNA in Children With Solid Tumors. JCO Precis Oncol. 2018; 2018.
journal title abbreviation: JCO Precis Oncol
publication date: 2018-07-05T00:00:00
year: 2018
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1086919
type: Authorship
author rank in publication: 33
linked author: Van Allen, Eliezer
linked information resource: Comprehensive Characterization of Cancer Driver Genes and Mutations.

Comprehensive Characterization of Cancer Driver Genes and Mutations.
PubMed Identifier: 30096302
author list: Bailey MH, Tokheim C, Porta-Pardo E, Sengupta S, Bertrand D, Weerasinghe A, Colaprico A, Wendl MC, Kim J, Reardon B, Kwok-Shing Ng P, Jeong KJ, Cao S, Wang Z, Gao J, Gao Q, Wang F, Liu EM, Mularoni L, Rubio-Perez C, Nagarajan N, Cortés-Ciriano I, Zhou DC, Liang WW, Hess JM, Yellapantula VD, Tamborero D, Gonzalez-Perez A, Suphavilai C, Ko JY, Khurana E, Park PJ, Van Allen EM, Liang H, Lawrence MS, Godzik A, Lopez-Bigas N, Stuart J, Wheeler D, Getz G, Chen K, Lazar AJ, Mills GB, Karchin R, Ding L
published in: Cell
information resource reference: Comprehensive Characterization of Cancer Driver Genes and Mutations. Cell. 2018 08 09; 174(4):1034-1035.
journal title abbreviation: Cell
publication date: 2018-08-09T00:00:00
year: 2018
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1088546
type: Authorship
author rank in publication: 9
linked author: Van Allen, Eliezer
linked information resource: Intron retention is a source of neoepitopes in cancer.

Intron retention is a source of neoepitopes in cancer.
PubMed Identifier: 30114007
author list: Smart AC, Margolis CA, Pimentel H, He MX, Miao D, Adeegbe D, Fugmann T, Wong KK, Van Allen EM
published in: Nature biotechnology
information resource reference: Intron retention is a source of neoepitopes in cancer. Nat Biotechnol. 2018 12; 36(11):1056-1058.
journal title abbreviation: Nat Biotechnol
publication date: 2018-08-16T00:00:00
year: 2018
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1088788
type: Authorship
author rank in publication: 7
linked author: Van Allen, Eliezer
linked information resource: Detection of circulating tumour DNA is associated with inferior outcomes in Ewing sarcoma and osteosarcoma: a report from the Children's Oncology Group.

Authorship 1089189
type: Authorship
author rank in publication: 11
linked author: Van Allen, Eliezer
linked information resource: A framework to rank genomic alterations as targets for cancer precision medicine: the ESMO Scale for Clinical Actionability of molecular Targets (ESCAT).

Detection of circulating tumour DNA is associated with inferior outcomes in Ewing sarcoma and osteosarcoma: a report from the Children's Oncology Group.
PubMed Identifier: 30131550
author list: Shulman DS, Klega K, Imamovic-Tuco A, Clapp A, Nag A, Thorner AR, Van Allen E, Ha G, Lessnick SL, Gorlick R, Janeway KA, Leavey PJ, Mascarenhas L, London WB, Vo KT, Stegmaier K, Hall D, Krailo MD, Barkauskas DA, DuBois SG, Crompton BD
published in: British journal of cancer
information resource reference: Detection of circulating tumour DNA is associated with inferior outcomes in Ewing sarcoma and osteosarcoma: a report from the Children's Oncology Group. Br J Cancer. 2018 08; 119(5):615-621.
journal title abbreviation: Br J Cancer
publication date: 2018-08-21T00:00:00
year: 2018
type: Academic Article
type: Article
type: Document
type: Information Resource

A framework to rank genomic alterations as targets for cancer precision medicine: the ESMO Scale for Clinical Actionability of molecular Targets (ESCAT).
PubMed Identifier: 30137196
author list: Mateo J, Chakravarty D, Dienstmann R, Jezdic S, Gonzalez-Perez A, Lopez-Bigas N, Ng CKY, Bedard PL, Tortora G, Douillard JY, Van Allen EM, Schultz N, Swanton C, André F, Pusztai L
published in: Annals of oncology : official journal of the European Society for Medical Oncology
information resource reference: A framework to rank genomic alterations as targets for cancer precision medicine: the ESMO Scale for Clinical Actionability of molecular Targets (ESCAT). Ann Oncol. 2018 09 01; 29(9):1895-1902.
journal title abbreviation: Ann Oncol
publication date: 2018-09-01T00:00:00
year: 2018
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1090308
type: Authorship
author rank in publication: 31
linked author: Van Allen, Eliezer
linked information resource: Genomic correlates of response to immune checkpoint blockade in microsatellite-stable solid tumors.

Genomic correlates of response to immune checkpoint blockade in microsatellite-stable solid tumors.
PubMed Identifier: 30150660
author list: Miao D, Margolis CA, Vokes NI, Liu D, Taylor-Weiner A, Wankowicz SM, Adeegbe D, Keliher D, Schilling B, Tracy A, Manos M, Chau NG, Hanna GJ, Polak P, Rodig SJ, Signoretti S, Sholl LM, Engelman JA, Getz G, Jänne PA, Haddad RI, Choueiri TK, Barbie DA, Haq R, Awad MM, Schadendorf D, Hodi FS, Bellmunt J, Wong KK, Hammerman P, Van Allen EM
published in: Nature genetics
information resource reference: Genomic correlates of response to immune checkpoint blockade in microsatellite-stable solid tumors. Nat Genet. 2018 09; 50(9):1271-1281.
journal title abbreviation: Nat Genet
publication date: 2018-08-27T00:00:00
year: 2018
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1091939
type: Authorship
author rank in publication: 51
linked author: Van Allen, Eliezer
linked information resource: Immunogenomic analyses associate immunological alterations with mismatch repair defects in prostate cancer.

Immunogenomic analyses associate immunological alterations with mismatch repair defects in prostate cancer.
PubMed Identifier: 30179225
author list: Nava Rodrigues D, Rescigno P, Liu D, Yuan W, Carreira S, Lambros MB, Seed G, Mateo J, Riisnaes R, Mullane S, Margolis C, Miao D, Miranda S, Dolling D, Clarke M, Bertan C, Crespo M, Boysen G, Ferreira A, Sharp A, Figueiredo I, Keliher D, Aldubayan S, Burke KP, Sumanasuriya S, Fontes MS, Bianchini D, Zafeiriou Z, Teixeira Mendes LS, Mouw K, Schweizer MT, Pritchard CC, Salipante S, Taplin ME, Beltran H, Rubin MA, Cieslik M, Robinson D, Heath E, Schultz N, Armenia J, Abida W, Scher H, Lord C, D'Andrea A, Sawyers CL, Chinnaiyan AM, Alimonti A, Nelson PS, Drake CG, Van Allen EM, de Bono JS
published in: The Journal of clinical investigation
information resource reference: Immunogenomic analyses associate immunological alterations with mismatch repair defects in prostate cancer. J Clin Invest. 2018 10 01; 128(10):4441-4453.
journal title abbreviation: J Clin Invest
publication date: 2018-09-04T00:00:00
year: 2018
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1093890
type: Authorship
author rank in publication: 12
linked author: Van Allen, Eliezer
linked information resource: Everolimus and pazopanib (E/P) benefit genomically selected patients with metastatic urothelial carcinoma.

Everolimus and pazopanib (E/P) benefit genomically selected patients with metastatic urothelial carcinoma.
PubMed Identifier: 30220708
author list: Bellmunt J, Lalani AA, Jacobus S, Wankowicz SA, Polacek L, Takeda DY, Harshman LC, Wagle N, Moreno I, Lundgren K, Bossé D, Van Allen EM, Choueiri TK, Rosenberg JE
published in: British journal of cancer
information resource reference: Everolimus and pazopanib (E/P) benefit genomically selected patients with metastatic urothelial carcinoma. Br J Cancer. 2018 09; 119(6):707-712.
journal title abbreviation: Br J Cancer
publication date: 2018-09-17T00:00:00
year: 2018
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1102949
type: Authorship
author rank in publication: 10
linked author: Van Allen, Eliezer
linked information resource: Transforming the Perioperative Treatment Paradigm in Non-Metastatic RCC-A Possible Path Forward.

Transforming the Perioperative Treatment Paradigm in Non-Metastatic RCC-A Possible Path Forward.
PubMed Identifier: 30334002
author list: Harshman LC, Drake CG, Haas NB, Manola J, Puligandla M, Signoretti S, Cella D, Gupta RT, Bhatt R, Van Allen E, Lara P, Choueiri TK, Kapoor A, Heng DYC, Shuch B, Jewett M, George D, Michaelson D, Carducci MA, McDermott D, Allaf M
published in: Kidney cancer (Clifton, Va.)
information resource reference: Transforming the Perioperative Treatment Paradigm in Non-Metastatic RCC-A Possible Path Forward. Kidney Cancer. 2017 Jul 26; 1(1):31-40.
journal title abbreviation: Kidney Cancer
publication date: 2017-07-26T00:00:00
year: 2017
type: Academic Article
type: Article
type: Document
type: Information Resource

A piece of my mind. Paracentesis by moonlight.
PubMed Identifier: 21521838
author list: Van Allen EM
published in: JAMA
information resource reference: A piece of my mind. Paracentesis by moonlight. JAMA. 2011 Apr 27; 305(16):1635-6.
journal title abbreviation: JAMA
publication date: 2011-04-27T00:00:00
year: 2011
type: Academic Article
type: Article
type: Document
type: Information Resource

A Common Language for Transformative Healthcare Networking
author list: Van Allen EM
published in: New England Journal of Medicine
information resource reference: A Common Language for Transformative Healthcare Networking. New England Journal of Medicine. 2012.
publication date: 2012-04-16T00:00:00
year: 2012
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1109786
type: Authorship
author rank in publication: 44
linked author: Van Allen, Eliezer
linked information resource: A Cancer Cell Program Promotes T Cell Exclusion and Resistance to Checkpoint Blockade.

Authorship 1109194
type: Authorship
author rank in publication: 51
linked author: Van Allen, Eliezer
linked information resource: Immunogenomic analyses associate immunological alterations with mismatch repair defects in prostate cancer.

A Cancer Cell Program Promotes T Cell Exclusion and Resistance to Checkpoint Blockade.
PubMed Identifier: 30388455
author list: Jerby-Arnon L, Shah P, Cuoco MS, Rodman C, Su MJ, Melms JC, Leeson R, Kanodia A, Mei S, Lin JR, Wang S, Rabasha B, Liu D, Zhang G, Margolais C, Ashenberg O, Ott PA, Buchbinder EI, Haq R, Hodi FS, Boland GM, Sullivan RJ, Frederick DT, Miao B, Moll T, Flaherty KT, Herlyn M, Jenkins RW, Thummalapalli R, Kowalczyk MS, Cañadas I, Schilling B, Cartwright ANR, Luoma AM, Malu S, Hwu P, Bernatchez C, Forget MA, Barbie DA, Shalek AK, Tirosh I, Sorger PK, Wucherpfennig K, Van Allen EM, Schadendorf D, Johnson BE, Rotem A, Rozenblatt-Rosen O, Garraway LA, Yoon CH, Izar B, Regev A
published in: Cell
information resource reference: A Cancer Cell Program Promotes T Cell Exclusion and Resistance to Checkpoint Blockade. Cell. 2018 11 01; 175(4):984-997.e24.
journal title abbreviation: Cell
publication date: 2018-11-01T00:00:00
year: 2018
type: Academic Article
type: Article
type: Document
type: Information Resource

Immunogenomic analyses associate immunological alterations with mismatch repair defects in prostate cancer.
PubMed Identifier: 30382943
author list: Rodrigues DN, Rescigno P, Liu D, Yuan W, Carreira S, Lambros MB, Seed G, Mateo J, Riisnaes R, Mullane S, Margolis C, Miao D, Miranda S, Dolling D, Clarke M, Bertan C, Crespo M, Boysen G, Ferreira A, Sharp A, Figueiredo I, Keliher D, Aldubayan S, Burke KP, Sumanasuriya S, Fontes MS, Bianchini D, Zafeiriou Z, Mendes LST, Mouw K, Schweizer MT, Pritchard CC, Salipante S, Taplin ME, Beltran H, Rubin MA, Cieslik M, Robinson D, Heath E, Schultz N, Armenia J, Abida W, Scher H, Lord C, D'Andrea A, Sawyers CL, Chinnaiyan AM, Alimonti A, Nelson PS, Drake CG, Van Allen EM, de Bono JS
published in: The Journal of clinical investigation
information resource reference: Immunogenomic analyses associate immunological alterations with mismatch repair defects in prostate cancer. J Clin Invest. 2018 11 01; 128(11):5185.
journal title abbreviation: J Clin Invest
publication date: 2018-11-01T00:00:00
year: 2018
type: Academic Article
type: Article
type: Document
type: Information Resource

Genomics of response to immune checkpoint therapies for cancer: implications for precision medicine.
PubMed Identifier: 30497521
author list: Conway JR, Kofman E, Mo SS, Elmarakeby H, Van Allen E
published in: Genome medicine
information resource reference: Genomics of response to immune checkpoint therapies for cancer: implications for precision medicine. Genome Med. 2018 11 29; 10(1):93.
journal title abbreviation: Genome Med
publication date: 2018-11-29T00:00:00
year: 2018
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1116275
type: Authorship
author rank in publication: 5
linked author: Van Allen, Eliezer
linked information resource: Genomics of response to immune checkpoint therapies for cancer: implications for precision medicine.

A role in transition.
PubMed Identifier: 19755369
author list: Van Allen EM
published in: Annals of internal medicine
information resource reference: A role in transition. Ann Intern Med. 2009 Sep 15; 151(6):427-8.
journal title abbreviation: Ann Intern Med
publication date: 2009-09-15T00:00:00
year: 2009
type: Academic Article
type: Article
type: Document
type: Information Resource

Transcriptomic Correlates of Response to Immune Checkpoint Therapies in Melanoma
end date: 2018-12-28T00:00:00
start date: 2018-01-01T00:00:00
type: Mentoring - Completed Student Project
overview: Soma Weiss

Expanding accessibility of a molecular oncology almanac for precision cancer medicine
end date: 2019-08-02T00:00:00
start date: 2018-08-06T00:00:00
type: Mentoring - Completed Student Project
overview: Soma Weiss

The paradox of positive thinking.
PubMed Identifier: 21422410
author list: Van Allen EM
published in: Journal of clinical oncology : official journal of the American Society of Clinical Oncology
information resource reference: The paradox of positive thinking. J Clin Oncol. 2011 Jul 01; 29(19):2730-1.
journal title abbreviation: J Clin Oncol
publication date: 2011-03-21T00:00:00
year: 2011
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1121892
type: Authorship
author rank in publication: 6
linked author: Van Allen, Eliezer
linked information resource: Mutational Analysis of 472 Urothelial Carcinoma Across Grades and Anatomic Sites.

Mutational Analysis of 472 Urothelial Carcinoma Across Grades and Anatomic Sites.
PubMed Identifier: 30593515
author list: Nassar AH, Umeton R, Kim J, Lundgren K, Harshman L, Van Allen EM, Preston M, Dong F, Bellmunt J, Mouw KW, Choueiri TK, Sonpavde G, Kwiatkowski DJ
published in: Clinical cancer research : an official journal of the American Association for Cancer Research
information resource reference: Mutational Analysis of 472 Urothelial Carcinoma Across Grades and Anatomic Sites. Clin Cancer Res. 2019 04 15; 25(8):2458-2470.
journal title abbreviation: Clin Cancer Res
publication date: 2018-12-28T00:00:00
year: 2018
type: Academic Article
type: Article
type: Document
type: Information Resource

Molecular and immune drivers of immunotherapy responsiveness in prostate cancer
end date: 2023-08-31
principal investigator name: FONG, LAWRENCE ;VAN ALLEN, ELIEZER M
start date: 2018-09-19
type: Grant
sponsor award id: U01CA233100

The Cellular Geography of Therapeutic Resistance in Cancer
end date: 2024-08-31
principal investigator name: JOHNSON, BRUCE E.
start date: 2018-09-24
type: Grant
sponsor award id: U2CCA233195

Principal Investigator
type: Researcher Role
researcher role of: Van Allen, Eliezer
contributes to: Molecular and immune drivers of immunotherapy responsiveness in prostate cancer

Authorship 1061
type: Authorship
author rank in publication: 1
linked author: Van Allen, Eliezer
linked information resource: A piece of my mind. Paracentesis by moonlight.

Authorship 12225
type: Authorship
author rank in publication: 1
linked author: Van Allen, Eliezer
linked information resource: Off-label use of rituximab in a multipayer insurance system.

Authorship 1127818
type: Authorship
author rank in publication: 26
linked author: Van Allen, Eliezer
linked information resource: Association of Inherited Pathogenic Variants in Checkpoint Kinase 2 (CHEK2) With Susceptibility to Testicular Germ Cell Tumors.

Association of Inherited Pathogenic Variants in Checkpoint Kinase 2 (CHEK2) With Susceptibility to Testicular Germ Cell Tumors.
PubMed Identifier: 30676620
author list: AlDubayan SH, Pyle LC, Gamulin M, Kulis T, Moore ND, Taylor-Weiner A, Hamid AA, Reardon B, Wubbenhorst B, Godse R, Vaughn DJ, Jacobs LA, Meien S, Grgic M, Kastelan Z, Markt SC, Damrauer SM, Rader DJ, Kember RL, Loud JT, Kanetsky PA, Greene MH, Sweeney CJ, Kubisch C, Nathanson KL, Van Allen EM, Stewart DR, Lessel D
published in: JAMA oncology
information resource reference: Association of Inherited Pathogenic Variants in Checkpoint Kinase 2 (CHEK2) With Susceptibility to Testicular Germ Cell Tumors. JAMA Oncol. 2019 Apr 01; 5(4):514-522.
journal title abbreviation: JAMA Oncol
publication date: 2019-04-01T00:00:00
year: 2019
type: Academic Article
type: Article
type: Document
type: Information Resource

https://connects.catalyst.harvard.edu/Profiles/profile/117510475
type: URLLink
label: http://vanallenlab.dana-farber.org
link anchor text: vanallenlab.dana-farber.org

Molecular origins and evolution to chemoresistance in germ cell tumors
end date: 2025-01-31
principal investigator name: VAN ALLEN, ELIEZER M
start date: 2018-02-01
type: Grant
sponsor award id: R37CA222574

Principal Investigator
type: Researcher Role
researcher role of: Van Allen, Eliezer
contributes to: Molecular origins and evolution to chemoresistance in germ cell tumors

Authorship 630140
type: Authorship
author rank in publication: 11
linked author: Van Allen, Eliezer
linked information resource: Punctuated evolution of prostate cancer genomes.

Authorship 630141
type: Authorship
author rank in publication: 1
linked author: Van Allen, Eliezer
linked information resource: Clinical analysis and interpretation of cancer genome data.

Authorship 1135517
type: Authorship
author rank in publication: 7
linked author: Van Allen, Eliezer
linked information resource: Correction: Detection of circulating tumour DNA is associated with inferior outcomes in Ewing sarcoma and osteosarcoma: a report from the Children's Oncology Group.

Authorship 1137638
type: Authorship
author rank in publication: 3
linked author: Van Allen, Eliezer
linked information resource: Genomic correlates of response to immune checkpoint blockade.

Correction: Detection of circulating tumour DNA is associated with inferior outcomes in Ewing sarcoma and osteosarcoma: a report from the Children's Oncology Group.
PubMed Identifier: 30880335
author list: Shulman DS, Klega K, Imamovic-Tuco A, Clapp A, Nag A, Thorner AR, Van Allen E, Ha G, Lessnick SL, Gorlick R, Janeway KA, Leavey PJ, Mascarenhas L, London WB, Vo KT, Stegmaier K, Hall D, Krailo MD, Barkauskas DA, DuBois SG, Crompton BD
published in: British journal of cancer
information resource reference: Correction: Detection of circulating tumour DNA is associated with inferior outcomes in Ewing sarcoma and osteosarcoma: a report from the Children's Oncology Group. Br J Cancer. 2019 Apr; 120(8):869.
journal title abbreviation: Br J Cancer
publication date: 2019-04-01T00:00:00
year: 2019
type: Academic Article
type: Article
type: Document
type: Information Resource

Genomic correlates of response to immune checkpoint blockade.
PubMed Identifier: 30842677
author list: Keenan TE, Burke KP, Van Allen EM
published in: Nature medicine
information resource reference: Genomic correlates of response to immune checkpoint blockade. Nat Med. 2019 03; 25(3):389-402.
journal title abbreviation: Nat Med
publication date: 2019-03-06T00:00:00
year: 2019
type: Academic Article
type: Article
type: Document
type: Information Resource

Drug Resistance, Neoplasm
MeSH DescriptorUI: D019008
MeSH semantic group name: Physiology
number of authors: 1448
number of publications: 5643
uniqueness weight: 0.327697
type: Concept

Clinical analysis and interpretation of cancer genome data.
PubMed Identifier: 23589549
author list: Van Allen EM, Wagle N, Levy MA
published in: Journal of clinical oncology : official journal of the American Society of Clinical Oncology
information resource reference: Clinical analysis and interpretation of cancer genome data. J Clin Oncol. 2013 May 20; 31(15):1825-33.
journal title abbreviation: J Clin Oncol
publication date: 2013-04-15T00:00:00
year: 2013
type: Academic Article
type: Article
type: Document
type: Information Resource

Carcinoma, Renal Cell
MeSH DescriptorUI: D002292
MeSH semantic group name: Disorders
number of authors: 765
number of publications: 3441
uniqueness weight: 0.327539
type: Concept

Genomics
MeSH DescriptorUI: D023281
MeSH semantic group name: Occupations
number of authors: 2037
number of publications: 6390
uniqueness weight: 0.308696
type: Concept

Kidney Neoplasms
MeSH DescriptorUI: D007680
MeSH semantic group name: Disorders
number of authors: 1043
number of publications: 4593
uniqueness weight: 0.293687
type: Concept

Authorship 1140372
type: Authorship
author rank in publication: 5
linked author: Van Allen, Eliezer
linked information resource: https://connects.catalyst.harvard.edu/Profiles/profile/72396259

Authorship 1142860
type: Authorship
author rank in publication: 9
linked author: Van Allen, Eliezer
linked information resource: Compound Genomic Alterations of TP53, PTEN, and RB1 Tumor Suppressors in Localized and Metastatic Prostate Cancer.

Compound Genomic Alterations of TP53, PTEN, and RB1 Tumor Suppressors in Localized and Metastatic Prostate Cancer.
PubMed Identifier: 30553611
author list: Hamid AA, Gray KP, Shaw G, MacConaill LE, Evan C, Bernard B, Loda M, Corcoran NM, Van Allen EM, Choudhury AD, Sweeney CJ
published in: European urology
information resource reference: Compound Genomic Alterations of TP53, PTEN, and RB1 Tumor Suppressors in Localized and Metastatic Prostate Cancer. Eur Urol. 2019 07; 76(1):89-97.
journal title abbreviation: Eur Urol
publication date: 2018-12-12T00:00:00
year: 2018
type: Academic Article
type: Article
type: Document
type: Information Resource

Neoplasms
MeSH DescriptorUI: D009369
MeSH semantic group name: Disorders
number of authors: 4708
number of publications: 23778
uniqueness weight: 0.125669
type: Concept

Authorship 1151395
type: Authorship
author rank in publication: 10
linked author: Van Allen, Eliezer
linked information resource: Genomic correlates of clinical outcome in advanced prostate cancer.

Genomic correlates of clinical outcome in advanced prostate cancer.
PubMed Identifier: 31061129
author list: Abida W, Cyrta J, Heller G, Prandi D, Armenia J, Coleman I, Cieslik M, Benelli M, Robinson D, Van Allen EM, Sboner A, Fedrizzi T, Mosquera JM, Robinson BD, De Sarkar N, Kunju LP, Tomlins S, Wu YM, Nava Rodrigues D, Loda M, Gopalan A, Reuter VE, Pritchard CC, Mateo J, Bianchini D, Miranda S, Carreira S, Rescigno P, Filipenko J, Vinson J, Montgomery RB, Beltran H, Heath EI, Scher HI, Kantoff PW, Taplin ME, Schultz N, deBono JS, Demichelis F, Nelson PS, Rubin MA, Chinnaiyan AM, Sawyers CL
published in: Proceedings of the National Academy of Sciences of the United States of America
information resource reference: Genomic correlates of clinical outcome in advanced prostate cancer. Proc Natl Acad Sci U S A. 2019 06 04; 116(23):11428-11436.
journal title abbreviation: Proc Natl Acad Sci U S A
publication date: 2019-05-06T00:00:00
year: 2019
type: Academic Article
type: Article
type: Document
type: Information Resource

Medicine
type: Department
type: Organization

Pediatrics
type: Department
type: Organization

Radiation Oncology
type: Department
type: Organization

Hematology/Oncology
type: Division
type: Organization

Oncology
type: Division
type: Organization

Channing Division of Network Medicine
type: Division
type: Organization

Beth Israel Deaconess Medical Center
type: Organization

Brigham and Women's Hospital
type: Organization

Dana-Farber Cancer Institute
type: Organization

Massachusetts General Hospital
type: Organization

Barabasi, Albert-Laszlo
eCommons Login: AB152
first name: Albert-Laszlo
last name: Barabasi
full name: Albert-Laszlo Barabasi, Ph.D.
has faculty rank: Lecturer
latitude: 42.33582300000000
longitude: -71.10748200000000
Person ID: 24039
person in primary position: Lecturer on Medicine, Part-time
type: Agent
type: Person
preferred title: Lecturer on Medicine, Part-time

NIkiforow, Sarah
eCommons Login: SN110
first name: Sarah
last name: NIkiforow
full name: Sarah NIkiforow, M.D.,Ph.D.
has faculty rank: Assistant Professor
latitude: 42.33582300000000
longitude: -71.10748200000000
Person ID: 92508
person in primary position: Assistant Professor of Medicine
type: Agent
type: Person
preferred title: Assistant Professor of Medicine

Authorship 1153876
type: Authorship
author rank in publication: 2
linked author: Van Allen, Eliezer
linked information resource: Mechanisms of Resistance to Immune Checkpoint Blockade: Why Does Checkpoint Inhibitor Immunotherapy Not Work for All Patients?

Mechanisms of Resistance to Immune Checkpoint Blockade: Why Does Checkpoint Inhibitor Immunotherapy Not Work for All Patients?
PubMed Identifier: 31099674
author list: Fares CM, Van Allen EM, Drake CG, Allison JP, Hu-Lieskovan S
published in: American Society of Clinical Oncology educational book. American Society of Clinical Oncology. Annual Meeting
information resource reference: Mechanisms of Resistance to Immune Checkpoint Blockade: Why Does Checkpoint Inhibitor Immunotherapy Not Work for All Patients? Am Soc Clin Oncol Educ Book. 2019 Jan; 39:147-164.
journal title abbreviation: Am Soc Clin Oncol Educ Book
publication date: 2019-05-17T00:00:00
year: 2019
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1157289
type: Authorship
author rank in publication: 40
linked author: Van Allen, Eliezer
linked information resource: Publisher Correction: The long tail of oncogenic drivers in prostate cancer.

Publisher Correction: The long tail of oncogenic drivers in prostate cancer.
PubMed Identifier: 31152158
author list: Armenia J, Wankowicz SAM, Liu D, Gao J, Kundra R, Reznik E, Chatila WK, Chakravarty D, Han GC, Coleman I, Montgomery B, Pritchard C, Morrissey C, Barbieri CE, Beltran H, Sboner A, Zafeiriou Z, Miranda S, Bielski CM, Penson AV, Tolonen C, Huang FW, Robinson D, Wu YM, Lonigro R, Garraway LA, Demichelis F, Kantoff PW, Taplin ME, Abida W, Taylor BS, Scher HI, Nelson PS, de Bono JS, Rubin MA, Sawyers CL, Chinnaiyan AM, Schultz N, Van Allen EM
published in: Nature genetics
information resource reference: Publisher Correction: The long tail of oncogenic drivers in prostate cancer. Nat Genet. 2019 Jul; 51(7):1194.
journal title abbreviation: Nat Genet
publication date: 2019-07-01T00:00:00
year: 2019
type: Academic Article
type: Article
type: Document
type: Information Resource

Choueiri, Toni
eCommons Login: TKC6
first name: Toni
last name: Choueiri
full name: Toni K. Choueiri, M.D.
has faculty rank: Full Professor
latitude: 42.33789600000000
longitude: -71.10724930000000
photo: https://connects.catalyst.harvard.edu/Profiles/profile/Modules/CustomViewPersonGeneralInfo/PhotoHandler.ashx
Person ID: 77491
person in primary position: Jerome and Nancy Kohlberg Professor of Medicine
type: Agent
type: Person
preferred title: Jerome and Nancy Kohlberg Professor of Medicine

Authorship 1159224
type: Authorship
author rank in publication: 18
linked author: Van Allen, Eliezer
linked information resource: Genomic Evolutionary Patterns of Leiomyosarcoma and Liposarcoma.

O'Donnell, Elizabeth
eCommons Login: EKO2
first name: Elizabeth
last name: O'Donnell
full name: Elizabeth Keating O'Donnell, M.D.
has faculty rank: Associate Professor
latitude: 42.33582300000000
longitude: -71.10748200000000
Person ID: 52036
person in primary position: Associate Professor of Medicine
type: Agent
type: Person
preferred title: Associate Professor of Medicine

Genomic Evolutionary Patterns of Leiomyosarcoma and Liposarcoma.
PubMed Identifier: 31164371
author list: Amin-Mansour A, George S, Sioletic S, Carter SL, Rosenberg M, Taylor-Weiner A, Stewart C, Chevalier A, Seepo S, Tracy A, Getz G, Hornick JL, Nucci MR, Quade B, Demetri GD, Raut CP, Garraway LA, Van Allen EM, Wagner AJ
published in: Clinical cancer research : an official journal of the American Association for Cancer Research
information resource reference: Genomic Evolutionary Patterns of Leiomyosarcoma and Liposarcoma. Clin Cancer Res. 2019 08 15; 25(16):5135-5142.
journal title abbreviation: Clin Cancer Res
publication date: 2019-06-04T00:00:00
year: 2019
type: Academic Article
type: Article
type: Document
type: Information Resource

Spektor, Alexander
eCommons Login: AS386
first name: Alexander
last name: Spektor
full name: Alexander Spektor, M.D.,Ph.D.
has faculty rank: Assistant Professor
latitude: 42.33582300000000
longitude: -71.10748200000000
Person ID: 37516
person in primary position: Assistant Professor of Radiation Oncology
type: Agent
type: Person
preferred title: Assistant Professor of Radiation Oncology

Bellmunt Molins, Joaquin
eCommons Login: JB208
first name: Joaquin
last name: Bellmunt Molins
full name: Joaquin Bellmunt Molins, M.D.
has faculty rank: Full Professor
Person ID: 72828
person in primary position: Professor of Medicine
type: Agent
type: Person
preferred title: Professor of Medicine

Enzinger, Andrea
eCommons Login: ACP10
first name: Andrea
last name: Enzinger
full name: Andrea Catherine Enzinger, M.D.
has faculty rank: Assistant Professor
latitude: 42.33582300000000
longitude: -71.10748200000000
Person ID: 20242
person in primary position: Assistant Professor of Medicine
type: Agent
type: Person
preferred title: Assistant Professor of Medicine

selected publications
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Authorship 1163092
type: Authorship
author rank in publication: 15
linked author: Van Allen, Eliezer
linked information resource: Intrinsic Resistance to Immune Checkpoint Blockade in a Mismatch Repair-Deficient Colorectal Cancer.

Intrinsic Resistance to Immune Checkpoint Blockade in a Mismatch Repair-Deficient Colorectal Cancer.
PubMed Identifier: 31217164
author list: Gurjao C, Liu D, Hofree M, AlDubayan SH, Wakiro I, Su MJ, Felt K, Gjini E, Brais LK, Rotem A, Rosenthal MH, Rozenblatt-Rosen O, Rodig S, Ng K, Van Allen EM, Corsello SM, Ogino S, Regev A, Nowak JA, Giannakis M
published in: Cancer immunology research
information resource reference: Intrinsic Resistance to Immune Checkpoint Blockade in a Mismatch Repair-Deficient Colorectal Cancer. Cancer Immunol Res. 2019 08; 7(8):1230-1236.
journal title abbreviation: Cancer Immunol Res
publication date: 2019-06-19T00:00:00
year: 2019
type: Academic Article
type: Article
type: Document
type: Information Resource

Flaherty, Keith
eCommons Login: KTF3
first name: Keith
last name: Flaherty
full name: Keith Thomas Flaherty, M.D.
has faculty rank: Full Professor
latitude: 42.36241700000000
longitude: -71.06893700000000
Person ID: 39135
person in primary position: Professor of Medicine
type: Agent
type: Person
preferred title: Professor of Medicine

Integrative Molecular Characterization of Resistance to Neoadjuvant Chemoradiation in Rectal Cancer.
PubMed Identifier: 31253631
author list: Kamran SC, Lennerz JK, Margolis CA, Liu D, Reardon B, Wankowicz SA, Van Seventer EE, Tracy A, Wo JY, Carter SL, Willers H, Corcoran RB, Hong TS, Van Allen EM
published in: Clinical cancer research : an official journal of the American Association for Cancer Research
information resource reference: Integrative Molecular Characterization of Resistance to Neoadjuvant Chemoradiation in Rectal Cancer. Clin Cancer Res. 2019 09 15; 25(18):5561-5571.
journal title abbreviation: Clin Cancer Res
publication date: 2019-06-28T00:00:00
year: 2019
type: Academic Article
type: Article
type: Document
type: Information Resource

Hodi, Frank
eCommons Login: FSH1
first name: Frank
last name: Hodi
full name: Frank Stephen Hodi, M.D.
has faculty rank: Full Professor
latitude: 42.33789600000000
longitude: -71.10724930000000
Person ID: 81575
person in primary position: Professor of Medicine
type: Agent
type: Person
preferred title: Professor of Medicine

Authorship 1168045
type: Authorship
author rank in publication: 14
linked author: Van Allen, Eliezer
linked information resource: Integrative Molecular Characterization of Resistance to Neoadjuvant Chemoradiation in Rectal Cancer.

McDermott, David
eCommons Login: DFM7
first name: David
last name: McDermott
full name: David Francis McDermott, M.D.
has faculty rank: Full Professor
Person ID: 83685
person in primary position: Victor J. Aresty Professor of Medicine
type: Agent
type: Person
preferred title: Victor J. Aresty Professor of Medicine

A statistical framework to systematically characterize cancer driver mutations in noncoding genomic regions
end date: 2021-06-30
principal investigator name: VAN ALLEN, ELIEZER M
start date: 2019-07-01
type: Grant
sponsor award id: R21CA242861

Principal Investigator
type: Researcher Role
researcher role of: Van Allen, Eliezer
contributes to: A statistical framework to systematically characterize cancer driver mutations in noncoding genomic regions

Authorship 1175382
type: Authorship
author rank in publication: 4
linked author: Van Allen, Eliezer
linked information resource: Assessment of Deep Natural Language Processing in Ascertaining Oncologic Outcomes From Radiology Reports.

Assessment of Deep Natural Language Processing in Ascertaining Oncologic Outcomes From Radiology Reports.
PubMed Identifier: 31343664
author list: Kehl KL, Elmarakeby H, Nishino M, Van Allen EM, Lepisto EM, Hassett MJ, Johnson BE, Schrag D
published in: JAMA oncology
information resource reference: Assessment of Deep Natural Language Processing in Ascertaining Oncologic Outcomes From Radiology Reports. JAMA Oncol. 2019 Oct 01; 5(10):1421-1429.
journal title abbreviation: JAMA Oncol
publication date: 2019-10-01T00:00:00
year: 2019
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1187727
type: Authorship
author rank in publication: 4
linked author: Van Allen, Eliezer
linked information resource: Clinical Validation of PBRM1 Alterations as a Marker of Immune Checkpoint Inhibitor Response in Renal Cell Carcinoma.

Clinical Validation of PBRM1 Alterations as a Marker of Immune Checkpoint Inhibitor Response in Renal Cell Carcinoma.
PubMed Identifier: 31486842
author list: Braun DA, Ishii Y, Walsh AM, Van Allen EM, Wu CJ, Shukla SA, Choueiri TK
published in: JAMA oncology
information resource reference: Clinical Validation of PBRM1 Alterations as a Marker of Immune Checkpoint Inhibitor Response in Renal Cell Carcinoma. JAMA Oncol. 2019 Nov 01; 5(11):1631-1633.
journal title abbreviation: JAMA Oncol
publication date: 2019-11-01T00:00:00
year: 2019
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1190691
type: Authorship
author rank in publication: 1
linked author: Van Allen, Eliezer
linked information resource: Finding the edge of the seat.

Finding the edge of the seat.
PubMed Identifier: 31501594
author list: Van Allen EM
published in: Nature medicine
information resource reference: Finding the edge of the seat. Nat Med. 2019 09; 25(9):1328.
journal title abbreviation: Nat Med
publication date: 2019-09-01T00:00:00
year: 2019
type: Academic Article
type: Article
type: Document
type: Information Resource

Metabolomic adaptations and correlates of survival to immune checkpoint blockade.
PubMed Identifier: 31554815
author list: Li H, Bullock K, Gurjao C, Braun D, Shukla SA, Bossé D, Lalani AA, Gopal S, Jin C, Horak C, Wind-Rotolo M, Signoretti S, McDermott DF, Freeman GJ, Van Allen EM, Schreiber SL, Stephen Hodi F, Sellers WR, Garraway LA, Clish CB, Choueiri TK, Giannakis M
published in: Nature communications
information resource reference: Metabolomic adaptations and correlates of survival to immune checkpoint blockade. Nat Commun. 2019 09 25; 10(1):4346.
journal title abbreviation: Nat Commun
publication date: 2019-09-25T00:00:00
year: 2019
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1192151
type: Authorship
author rank in publication: 15
linked author: Van Allen, Eliezer
linked information resource: Metabolomic adaptations and correlates of survival to immune checkpoint blockade.

Authorship 163165
type: Authorship
author rank in publication: 1
linked author: Van Allen, Eliezer
linked information resource: One day later. Continuing psychological stress after a cardiac intensive care rotation.

Authorship 1200350
type: Authorship
author rank in publication: 8
linked author: Van Allen, Eliezer
linked information resource: Scaling computational genomics to millions of individuals with GPUs.

Scaling computational genomics to millions of individuals with GPUs.
PubMed Identifier: 31675989
author list: Taylor-Weiner A, Aguet F, Haradhvala NJ, Gosai S, Anand S, Kim J, Ardlie K, Van Allen EM, Getz G
published in: Genome biology
information resource reference: Scaling computational genomics to millions of individuals with GPUs. Genome Biol. 2019 11 01; 20(1):228.
journal title abbreviation: Genome Biol
publication date: 2019-11-01T00:00:00
year: 2019
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 142112
type: Authorship
author rank in publication: 3
linked author: Van Allen, Eliezer
linked information resource: A genome-scale RNA interference screen implicates NF1 loss in resistance to RAF inhibition.

Results of a Multicenter Phase II Study of Atezolizumab and Bevacizumab for Patients With Metastatic Renal Cell Carcinoma With Variant Histology and/or Sarcomatoid Features.
PubMed Identifier: 31721643
author list: McGregor BA, McKay RR, Braun DA, Werner L, Gray K, Flaifel A, Signoretti S, Hirsch MS, Steinharter JA, Bakouny Z, Flippot R, Wei XX, Choudhury A, Kilbridge K, Freeman GJ, Van Allen EM, Harshman LC, McDermott DF, Vaishampayan U, Choueiri TK
published in: Journal of clinical oncology : official journal of the American Society of Clinical Oncology
information resource reference: Results of a Multicenter Phase II Study of Atezolizumab and Bevacizumab for Patients With Metastatic Renal Cell Carcinoma With Variant Histology and/or Sarcomatoid Features. J Clin Oncol. 2020 01 01; 38(1):63-70.
journal title abbreviation: J Clin Oncol
publication date: 2019-11-13T00:00:00
year: 2019
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1205227
type: Authorship
author rank in publication: 29
linked author: Van Allen, Eliezer
linked information resource: CREB5 Promotes Resistance to Androgen-Receptor Antagonists and Androgen Deprivation in Prostate Cancer.

Authorship 1204667
type: Authorship
author rank in publication: 16
linked author: Van Allen, Eliezer
linked information resource: Results of a Multicenter Phase II Study of Atezolizumab and Bevacizumab for Patients With Metastatic Renal Cell Carcinoma With Variant Histology and/or Sarcomatoid Features.

CREB5 Promotes Resistance to Androgen-Receptor Antagonists and Androgen Deprivation in Prostate Cancer.
PubMed Identifier: 31747605
author list: Hwang JH, Seo JH, Beshiri ML, Wankowicz S, Liu D, Cheung A, Li J, Qiu X, Hong AL, Botta G, Golumb L, Richter C, So J, Sandoval GJ, Giacomelli AO, Ly SH, Han C, Dai C, Pakula H, Sheahan A, Piccioni F, Gjoerup O, Loda M, Sowalsky AG, Ellis L, Long H, Root DE, Kelly K, Van Allen EM, Freedman ML, Choudhury AD, Hahn WC
published in: Cell reports
information resource reference: CREB5 Promotes Resistance to Androgen-Receptor Antagonists and Androgen Deprivation in Prostate Cancer. Cell Rep. 2019 11 19; 29(8):2355-2370.e6.
journal title abbreviation: Cell Rep
publication date: 2019-11-19T00:00:00
year: 2019
type: Academic Article
type: Article
type: Document
type: Information Resource

Assistant Professor of Medicine
is primary position: true
position in department: Medicine
position in division: Oncology
sort order: 1
type: Position
HR job title: Assistant Professor of Medicine
position in organization: Dana-Farber Cancer Institute

Authorship 1207815
type: Authorship
author rank in publication: 35
linked author: Van Allen, Eliezer
linked information resource: Integrative molecular and clinical modeling of clinical outcomes to PD1 blockade in patients with metastatic melanoma.

Integrative molecular and clinical modeling of clinical outcomes to PD1 blockade in patients with metastatic melanoma.
PubMed Identifier: 31792460
author list: Liu D, Schilling B, Liu D, Sucker A, Livingstone E, Jerby-Arnon L, Zimmer L, Gutzmer R, Satzger I, Loquai C, Grabbe S, Vokes N, Margolis CA, Conway J, He MX, Elmarakeby H, Dietlein F, Miao D, Tracy A, Gogas H, Goldinger SM, Utikal J, Blank CU, Rauschenberg R, von Bubnoff D, Krackhardt A, Weide B, Haferkamp S, Kiecker F, Izar B, Garraway L, Regev A, Flaherty K, Paschen A, Van Allen EM, Schadendorf D
published in: Nature medicine
information resource reference: Integrative molecular and clinical modeling of clinical outcomes to PD1 blockade in patients with metastatic melanoma. Nat Med. 2019 12; 25(12):1916-1927.
journal title abbreviation: Nat Med
publication date: 2019-12-02T00:00:00
year: 2019
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1210535
type: Authorship
author rank in publication: 13
linked author: Van Allen, Eliezer
linked information resource: Prevalence of pathogenic germline cancer risk variants in high-risk urothelial carcinoma.

Authorship 1211579
type: Authorship
author rank in publication: 20
linked author: Van Allen, Eliezer
linked information resource: Harmonization of Tumor Mutational Burden Quantification and Association With Response to Immune Checkpoint Blockade in Non-Small-Cell Lung Cancer.

Authorship 1212652
type: Authorship
author rank in publication: 9
linked author: Van Allen, Eliezer
linked information resource: A model combining clinical and genomic factors to predict response to PD-1/PD-L1 blockade in advanced urothelial carcinoma.

Prevalence of pathogenic germline cancer risk variants in high-risk urothelial carcinoma.
PubMed Identifier: 31844177
author list: Nassar AH, Abou Alaiwi S, AlDubayan SH, Moore N, Mouw KW, Kwiatkowski DJ, Choueiri TK, Curran C, Berchuck JE, Harshman LC, Nuzzo PV, Chanza NM, Van Allen E, Esplin ED, Yang S, Callis T, Garber JE, Rana HQ, Sonpavde G
published in: Genetics in medicine : official journal of the American College of Medical Genetics
information resource reference: Prevalence of pathogenic germline cancer risk variants in high-risk urothelial carcinoma. Genet Med. 2020 04; 22(4):709-718.
journal title abbreviation: Genet Med
publication date: 2019-12-17T00:00:00
year: 2019
type: Academic Article
type: Article
type: Document
type: Information Resource

Harmonization of Tumor Mutational Burden Quantification and Association With Response to Immune Checkpoint Blockade in Non-Small-Cell Lung Cancer.
PubMed Identifier: 31832578
author list: Vokes NI, Liu D, Ricciuti B, Jimenez-Aguilar E, Rizvi H, Dietlein F, He MX, Margolis CA, Elmarakeby HA, Girshman J, Adeni A, Sanchez-Vega F, Schultz N, Dahlberg S, Zehir A, Jänne PA, Nishino M, Umeton R, Sholl LM, Van Allen EM, Hellmann MD, Awad MM
published in: JCO precision oncology
information resource reference: Harmonization of Tumor Mutational Burden Quantification and Association With Response to Immune Checkpoint Blockade in Non-Small-Cell Lung Cancer. JCO Precis Oncol. 2019; 3.
journal title abbreviation: JCO Precis Oncol
publication date: 2019-11-12T00:00:00
year: 2019
type: Academic Article
type: Article
type: Document
type: Information Resource

A model combining clinical and genomic factors to predict response to PD-1/PD-L1 blockade in advanced urothelial carcinoma.
PubMed Identifier: 31857723
author list: Nassar AH, Mouw KW, Jegede O, Shinagare AB, Kim J, Liu CJ, Pomerantz M, Harshman LC, Van Allen EM, Wei XX, McGregor B, Choudhury AD, Preston MA, Dong F, Signoretti S, Lindeman NI, Bellmunt J, Choueiri TK, Sonpavde G, Kwiatkowski DJ
published in: British journal of cancer
information resource reference: A model combining clinical and genomic factors to predict response to PD-1/PD-L1 blockade in advanced urothelial carcinoma. Br J Cancer. 2020 02; 122(4):555-563.
journal title abbreviation: Br J Cancer
publication date: 2019-12-20T00:00:00
year: 2019
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1223181
type: Authorship
author rank in publication: 4
linked author: Van Allen, Eliezer
linked information resource: The role of site-specific therapy for cancers of unknown of primary: A meta-analysis.

Authorship 1223020
type: Authorship
author rank in publication: 8
linked author: Van Allen, Eliezer
linked information resource: Identification of cancer driver genes based on nucleotide context.

Authorship 1223115
type: Authorship
author rank in publication: 20
linked author: Van Allen, Eliezer
linked information resource: Tumor Mutational Burden and PTEN Alterations as Molecular Correlates of Response to PD-1/L1 Blockade in Metastatic Triple-Negative Breast Cancer.

Identification of cancer driver genes based on nucleotide context.
PubMed Identifier: 32015527
author list: Dietlein F, Weghorn D, Taylor-Weiner A, Richters A, Reardon B, Liu D, Lander ES, Van Allen EM, Sunyaev SR
published in: Nature genetics
information resource reference: Identification of cancer driver genes based on nucleotide context. Nat Genet. 2020 02; 52(2):208-218.
journal title abbreviation: Nat Genet
publication date: 2020-02-03T00:00:00
year: 2020
type: Academic Article
type: Article
type: Document
type: Information Resource

The role of site-specific therapy for cancers of unknown of primary: A meta-analysis.
PubMed Identifier: 32007711
author list: Rassy E, Bakouny Z, Choueiri TK, Van Allen EM, Fizazi K, Greco FA, Pavlidis N
published in: European journal of cancer (Oxford, England : 1990)
information resource reference: The role of site-specific therapy for cancers of unknown of primary: A meta-analysis. Eur J Cancer. 2020 03; 127:118-122.
journal title abbreviation: Eur J Cancer
publication date: 2020-01-30T00:00:00
year: 2020
type: Academic Article
type: Article
type: Document
type: Information Resource

Tumor Mutational Burden and PTEN Alterations as Molecular Correlates of Response to PD-1/L1 Blockade in Metastatic Triple-Negative Breast Cancer.
PubMed Identifier: 32019858
author list: Barroso-Sousa R, Keenan TE, Pernas S, Exman P, Jain E, Garrido-Castro AC, Hughes M, Bychkovsky B, Umeton R, Files JL, Lindeman NI, MacConaill LE, Hodi FS, Krop IE, Dillon D, Winer EP, Wagle N, Lin NU, Mittendorf EA, Van Allen EM, Tolaney SM
published in: Clinical cancer research : an official journal of the American Association for Cancer Research
information resource reference: Tumor Mutational Burden and PTEN Alterations as Molecular Correlates of Response to PD-1/L1 Blockade in Metastatic Triple-Negative Breast Cancer. Clin Cancer Res. 2020 06 01; 26(11):2565-2572.
journal title abbreviation: Clin Cancer Res
publication date: 2020-02-04T00:00:00
year: 2020
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1231606
type: Authorship
author rank in publication: 13
linked author: Van Allen, Eliezer
linked information resource: ATM Loss Confers Greater Sensitivity to ATR Inhibition Than PARP Inhibition in Prostate Cancer.

Authorship 1233446
type: Authorship
author rank in publication: 6
linked author: Van Allen, Eliezer
linked information resource: Germline Features Associated with Immune Infiltration in Solid Tumors.

ATM Loss Confers Greater Sensitivity to ATR Inhibition Than PARP Inhibition in Prostate Cancer.
PubMed Identifier: 32127357
author list: Rafiei S, Fitzpatrick K, Liu D, Cai MY, Elmarakeby HA, Park J, Ricker C, Kochupurakkal BS, Choudhury AD, Hahn WC, Balk SP, Hwang JH, Van Allen EM, Mouw KW
published in: Cancer research
information resource reference: ATM Loss Confers Greater Sensitivity to ATR Inhibition Than PARP Inhibition in Prostate Cancer. Cancer Res. 2020 06 01; 80(11):2094-2100.
journal title abbreviation: Cancer Res
publication date: 2020-03-03T00:00:00
year: 2020
type: Academic Article
type: Article
type: Document
type: Information Resource

Germline Features Associated with Immune Infiltration in Solid Tumors.
PubMed Identifier: 32130895
author list: Shahamatdar S, He MX, Reyna MA, Gusev A, AlDubayan SH, Van Allen EM, Ramachandran S
published in: Cell reports
information resource reference: Germline Features Associated with Immune Infiltration in Solid Tumors. Cell Rep. 2020 03 03; 30(9):2900-2908.e4.
journal title abbreviation: Cell Rep
publication date: 2020-03-03T00:00:00
year: 2020
type: Academic Article
type: Article
type: Document
type: Information Resource

Mammalian SWI/SNF Complex Genomic Alterations and Immune Checkpoint Blockade in Solid Tumors.
PubMed Identifier: 32321774
author list: Abou Alaiwi S, Nassar AH, Xie W, Bakouny Z, Berchuck JE, Braun DA, Baca SC, Nuzzo PV, Flippot R, Mouhieddine TH, Spurr LF, Li YY, Li T, Flaifel A, Steinharter JA, Margolis CA, Vokes NI, Du H, Shukla SA, Cherniack AD, Sonpavde G, Haddad RI, Awad MM, Giannakis M, Hodi FS, Liu XS, Signoretti S, Kadoch C, Freedman ML, Kwiatkowski DJ, Van Allen EM, Choueiri TK
published in: Cancer immunology research
information resource reference: Mammalian SWI/SNF Complex Genomic Alterations and Immune Checkpoint Blockade in Solid Tumors. Cancer Immunol Res. 2020 08; 8(8):1075-1084.
journal title abbreviation: Cancer Immunol Res
publication date: 2020-04-22T00:00:00
year: 2020
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1242288
type: Authorship
author rank in publication: 31
linked author: Van Allen, Eliezer
linked information resource: Mammalian SWI/SNF Complex Genomic Alterations and Immune Checkpoint Blockade in Solid Tumors.

Characterizing diversity in the tumor-immune microenvironment of distinct subclasses of gastroesophageal adenocarcinomas.
PubMed Identifier: 32387455
author list: Derks S, de Klerk LK, Xu X, Fleitas T, Liu KX, Liu Y, Dietlein F, Margolis C, Chiaravalli AM, Da Silva AC, Ogino S, Akarca FG, Freeman GJ, Rodig SJ, Hornick JL, van Allen E, Li B, Liu SX, Thorsson V, Bass AJ
published in: Annals of oncology : official journal of the European Society for Medical Oncology
information resource reference: Characterizing diversity in the tumor-immune microenvironment of distinct subclasses of gastroesophageal adenocarcinomas. Ann Oncol. 2020 08; 31(8):1011-1020.
journal title abbreviation: Ann Oncol
publication date: 2020-05-06T00:00:00
year: 2020
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1244628
type: Authorship
author rank in publication: 23
linked author: Van Allen, Eliezer
linked information resource: Inactivation of Fbxw7 Impairs dsRNA Sensing and Confers Resistance to PD-1 Blockade.

Inactivation of Fbxw7 Impairs dsRNA Sensing and Confers Resistance to PD-1 Blockade.
PubMed Identifier: 32371478
author list: Gstalder C, Liu D, Miao D, Lutterbach B, DeVine AL, Lin C, Shettigar M, Pancholi P, Buchbinder EI, Carter SL, Manos MP, Rojas-Rudilla V, Brennick R, Gjini E, Chen PH, Lako A, Rodig S, Yoon CH, Freeman GJ, Barbie DA, Hodi FS, Miles W, Van Allen EM, Haq R
published in: Cancer discovery
information resource reference: Inactivation of Fbxw7 Impairs dsRNA Sensing and Confers Resistance to PD-1 Blockade. Cancer Discov. 2020 09; 10(9):1296-1311.
journal title abbreviation: Cancer Discov
publication date: 2020-05-05T00:00:00
year: 2020
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1246958
type: Authorship
author rank in publication: 16
linked author: Van Allen, Eliezer
linked information resource: Characterizing diversity in the tumor-immune microenvironment of distinct subclasses of gastroesophageal adenocarcinomas.

Authorship 1246876
type: Authorship
author rank in publication: 26
linked author: Van Allen, Eliezer
linked information resource: Targeting the innate immunoreceptor RIG-I overcomes melanoma-intrinsic resistance to T cell immunotherapy.

Authorship 1248889
type: Authorship
author rank in publication: 18
linked author: Van Allen, Eliezer
linked information resource: Genomic Profiling of Smoldering Multiple Myeloma Identifies Patients at a High Risk of Disease Progression.

Genomic Profiling of Smoldering Multiple Myeloma Identifies Patients at a High Risk of Disease Progression.
PubMed Identifier: 32442065
author list: Bustoros M, Sklavenitis-Pistofidis R, Park J, Redd R, Zhitomirsky B, Dunford AJ, Salem K, Tai YT, Anand S, Mouhieddine TH, Chavda SJ, Boehner C, Elagina L, Neuse CJ, Cha J, Rahmat M, Taylor-Weiner A, Van Allen E, Kumar S, Kastritis E, Leshchiner I, Morgan EA, Laubach J, Casneuf T, Richardson P, Munshi NC, Anderson KC, Trippa L, Aguet F, Stewart C, Dimopoulos MA, Yong K, Bergsagel PL, Manier S, Getz G, Ghobrial IM
published in: Journal of clinical oncology : official journal of the American Society of Clinical Oncology
information resource reference: Genomic Profiling of Smoldering Multiple Myeloma Identifies Patients at a High Risk of Disease Progression. J Clin Oncol. 2020 07 20; 38(21):2380-2389.
journal title abbreviation: J Clin Oncol
publication date: 2020-05-22T00:00:00
year: 2020
type: Academic Article
type: Article
type: Document
type: Information Resource

Targeting the innate immunoreceptor RIG-I overcomes melanoma-intrinsic resistance to T cell immunotherapy.
PubMed Identifier: 32427578
author list: Such L, Zhao F, Liu D, Thier B, Le-Trilling VTK, Sucker A, Coch C, Pieper N, Howe S, Bhat H, Kalkavan H, Ritter C, Brinkhaus R, Ugurel S, Köster J, Seifert U, Dittmer U, Schuler M, Lang KS, Kufer TA, Hartmann G, Becker JC, Horn S, Ferrone S, Liu D, Van Allen EM, Schadendorf D, Griewank K, Trilling M, Paschen A
published in: The Journal of clinical investigation
information resource reference: Targeting the innate immunoreceptor RIG-I overcomes melanoma-intrinsic resistance to T cell immunotherapy. J Clin Invest. 2020 08 03; 130(8):4266-4281.
journal title abbreviation: J Clin Invest
publication date: 2020-08-03T00:00:00
year: 2020
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1251259
type: Authorship
author rank in publication: 22
linked author: Van Allen, Eliezer
linked information resource: Interplay of somatic alterations and immune infiltration modulates response to PD-1 blockade in advanced clear cell renal cell carcinoma.

Interplay of somatic alterations and immune infiltration modulates response to PD-1 blockade in advanced clear cell renal cell carcinoma.
PubMed Identifier: 32472114
author list: Braun DA, Hou Y, Bakouny Z, Ficial M, Sant' Angelo M, Forman J, Ross-Macdonald P, Berger AC, Jegede OA, Elagina L, Steinharter J, Sun M, Wind-Rotolo M, Pignon JC, Cherniack AD, Lichtenstein L, Neuberg D, Catalano P, Freeman GJ, Sharpe AH, McDermott DF, Van Allen EM, Signoretti S, Wu CJ, Shukla SA, Choueiri TK
published in: Nature medicine
information resource reference: Interplay of somatic alterations and immune infiltration modulates response to PD-1 blockade in advanced clear cell renal cell carcinoma. Nat Med. 2020 06; 26(6):909-918.
journal title abbreviation: Nat Med
publication date: 2020-05-29T00:00:00
year: 2020
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1252957
type: Authorship
author rank in publication: 4
linked author: Van Allen, Eliezer
linked information resource: CoMut: visualizing integrated molecular information with comutation plots.

CoMut: visualizing integrated molecular information with comutation plots.
PubMed Identifier: 32502231
author list: Crowdis J, He MX, Reardon B, Van Allen EM
published in: Bioinformatics (Oxford, England)
information resource reference: CoMut: visualizing integrated molecular information with comutation plots. Bioinformatics. 2020 08 01; 36(15):4348-4349.
journal title abbreviation: Bioinformatics
publication date: 2020-08-01T00:00:00
year: 2020
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1254741
type: Authorship
author rank in publication: 35
linked author: Van Allen, Eliezer
linked information resource: Author Correction: Integrative molecular and clinical modeling of clinical outcomes to PD1 blockade in patients with metastatic melanoma.

Authorship 1255944
type: Authorship
author rank in publication: 21
linked author: Van Allen, Eliezer
linked information resource: Clonal hematopoiesis is associated with adverse outcomes in multiple myeloma patients undergoing transplant.

Authorship 1256968
type: Authorship
author rank in publication: 22
linked author: Van Allen, Eliezer
linked information resource: Cancer Moonshot Immuno-Oncology Translational Network (IOTN): accelerating the clinical translation of basic discoveries for improving immunotherapy and immunoprevention of cancer.

Clonal hematopoiesis is associated with adverse outcomes in multiple myeloma patients undergoing transplant.
PubMed Identifier: 32533060
author list: Mouhieddine TH, Sperling AS, Redd R, Park J, Leventhal M, Gibson CJ, Manier S, Nassar AH, Capelletti M, Huynh D, Bustoros M, Sklavenitis-Pistofidis R, Tahri S, Hornburg K, Dumke H, Itani MM, Boehner CJ, Liu CJ, AlDubayan SH, Reardon B, Van Allen EM, Keats JJ, Stewart C, Mehr S, Auclair D, Schlossman RL, Munshi NC, Anderson KC, Steensma DP, Laubach JP, Richardson PG, Ritz J, Ebert BL, Soiffer RJ, Trippa L, Getz G, Neuberg DS, Ghobrial IM
published in: Nature communications
information resource reference: Clonal hematopoiesis is associated with adverse outcomes in multiple myeloma patients undergoing transplant. Nat Commun. 2020 06 12; 11(1):2996.
journal title abbreviation: Nat Commun
publication date: 2020-06-12T00:00:00
year: 2020
type: Academic Article
type: Article
type: Document
type: Information Resource

Author Correction: Integrative molecular and clinical modeling of clinical outcomes to PD1 blockade in patients with metastatic melanoma.
PubMed Identifier: 32561875
author list: Liu D, Schilling B, Liu D, Sucker A, Livingstone E, Jerby-Arnon L, Zimmer L, Gutzmer R, Satzger I, Loquai C, Grabbe S, Vokes N, Margolis CA, Conway J, He MX, Elmarakeby H, Dietlein F, Miao D, Tracy A, Gogas H, Goldinger SM, Utikal J, Blank CU, Rauschenberg R, von Bubnoff D, Krackhardt A, Weide B, Haferkamp S, Kiecker F, Izar B, Garraway L, Regev A, Flaherty K, Paschen A, Van Allen EM, Schadendorf D
published in: Nature medicine
information resource reference: Author Correction: Integrative molecular and clinical modeling of clinical outcomes to PD1 blockade in patients with metastatic melanoma. Nat Med. 2020 Jul; 26(7):1147.
journal title abbreviation: Nat Med
publication date: 2020-07-01T00:00:00
year: 2020
type: Academic Article
type: Article
type: Document
type: Information Resource

Cancer Moonshot Immuno-Oncology Translational Network (IOTN): accelerating the clinical translation of basic discoveries for improving immunotherapy and immunoprevention of cancer.
PubMed Identifier: 32554617
author list: Annapragada A, Sikora A, Bollard C, Conejo-Garcia J, Cruz CR, Demehri S, Demetriou M, Demirdjian L, Fong L, Horowitz M, Hutson A, Kadash-Edmondson K, Kufe D, Lipkin S, Liu S, McCarthy C, Morgan M, Morris Z, Pan Y, Pasquini M, Schoenberger S, Van Allen E, Vilar E, Xing Y, Zha W, Odunsi A
published in: Journal for immunotherapy of cancer
information resource reference: Cancer Moonshot Immuno-Oncology Translational Network (IOTN): accelerating the clinical translation of basic discoveries for improving immunotherapy and immunoprevention of cancer. J Immunother Cancer. 2020 06; 8(1).
journal title abbreviation: J Immunother Cancer
publication date: 2020-06-01T00:00:00
year: 2020
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1258050
type: Authorship
author rank in publication: 8
linked author: Van Allen, Eliezer
linked information resource: FiTAc-seq: fixed-tissue ChIP-seq for H3K27ac profiling and super-enhancer analysis of FFPE tissues.

FiTAc-seq: fixed-tissue ChIP-seq for H3K27ac profiling and super-enhancer analysis of FFPE tissues.
PubMed Identifier: 32591768
author list: Font-Tello A, Kesten N, Xie Y, Taing L, Varešlija D, Young LS, Hamid AA, Van Allen EM, Sweeney CJ, Gjini E, Lako A, Hodi FS, Bellmunt J, Brown M, Cejas P, Long HW
published in: Nature protocols
information resource reference: FiTAc-seq: fixed-tissue ChIP-seq for H3K27ac profiling and super-enhancer analysis of FFPE tissues. Nat Protoc. 2020 08; 15(8):2503-2518.
journal title abbreviation: Nat Protoc
publication date: 2020-06-26T00:00:00
year: 2020
type: Academic Article
type: Article
type: Document
type: Information Resource

Assistant Professor of Medicine
is primary position: true
position in department: Medicine
position in division: Oncology
sort order: 1
type: Position
HR job title: Assistant Professor of Medicine
position in organization: Dana-Farber Cancer Institute

Authorship 1272438
type: Authorship
author rank in publication: 6
linked author: Van Allen, Eliezer
linked information resource: Natural Language Processing to Ascertain Cancer Outcomes From Medical Oncologist Notes.

Authorship 1274078
type: Authorship
author rank in publication: 17
linked author: Van Allen, Eliezer
linked information resource: A phase 2 trial of buparlisib in patients with platinum-resistant metastatic urothelial carcinoma.

Natural Language Processing to Ascertain Cancer Outcomes From Medical Oncologist Notes.
PubMed Identifier: 32755459
author list: Kehl KL, Xu W, Lepisto E, Elmarakeby H, Hassett MJ, Van Allen EM, Johnson BE, Schrag D
published in: JCO clinical cancer informatics
information resource reference: Natural Language Processing to Ascertain Cancer Outcomes From Medical Oncologist Notes. JCO Clin Cancer Inform. 2020 08; 4:680-690.
journal title abbreviation: JCO Clin Cancer Inform
publication date: 2020-08-01T00:00:00
year: 2020
type: Academic Article
type: Article
type: Document
type: Information Resource

A phase 2 trial of buparlisib in patients with platinum-resistant metastatic urothelial carcinoma.
PubMed Identifier: 32767682
author list: McPherson V, Reardon B, Bhayankara A, Scott SN, Boyd ME, Garcia-Grossman IR, Regazzi AM, McCoy AS, Kim PH, Al-Ahmadie H, Ostrovnaya I, Roth AJ, Farooki A, Berger MF, Rosenberg JE, Solit DB, Van Allen E, Milowsky MI, Bajorin DF, Iyer G
published in: Cancer
information resource reference: A phase 2 trial of buparlisib in patients with platinum-resistant metastatic urothelial carcinoma. Cancer. 2020 10 15; 126(20):4532-4544.
journal title abbreviation: Cancer
publication date: 2020-08-07T00:00:00
year: 2020
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1279862
type: Authorship
author rank in publication: 2
linked author: Van Allen, Eliezer
linked information resource: Integrated Analysis of Germ Cell Tumors.

Integrated Analysis of Germ Cell Tumors.
PubMed Identifier: 32852765
author list: Tewari A, Van Allen E
published in: Methods in molecular biology (Clifton, N.J.)
information resource reference: Integrated Analysis of Germ Cell Tumors. Methods Mol Biol. 2021; 2195:181-187.
journal title abbreviation: Methods Mol Biol
publication date: 2021-01-01T00:00:00
year: 2021
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1281469
type: Authorship
author rank in publication: 17
linked author: Van Allen, Eliezer
linked information resource: Effect of Eribulin With or Without Pembrolizumab on Progression-Free Survival for Patients With Hormone Receptor-Positive, ERBB2-Negative Metastatic Breast Cancer: A Randomized Clinical Trial.

Authorship 1282402
type: Authorship
author rank in publication: 19
linked author: Van Allen, Eliezer
linked information resource: Genomic Predictors of Good Outcome, Recurrence, or Progression in High-Grade T1 Non-Muscle-Invasive Bladder Cancer.

Genomic Predictors of Good Outcome, Recurrence, or Progression in High-Grade T1 Non-Muscle-Invasive Bladder Cancer.
PubMed Identifier: 32868381
author list: Bellmunt J, Kim J, Reardon B, Perera-Bel J, Orsola A, Rodriguez-Vida A, Wankowicz SA, Bowden M, Barletta JA, Morote J, de Torres I, Juanpere N, Lloreta-Trull J, Hernandez S, Mouw KW, Taplin ME, Cejas P, Long HW, Van Allen EM, Getz G, Kwiatkowski DJ
published in: Cancer research
information resource reference: Genomic Predictors of Good Outcome, Recurrence, or Progression in High-Grade T1 Non-Muscle-Invasive Bladder Cancer. Cancer Res. 2020 10 15; 80(20):4476-4486.
journal title abbreviation: Cancer Res
publication date: 2020-08-31T00:00:00
year: 2020
type: Academic Article
type: Article
type: Document
type: Information Resource

Effect of Eribulin With or Without Pembrolizumab on Progression-Free Survival for Patients With Hormone Receptor-Positive, ERBB2-Negative Metastatic Breast Cancer: A Randomized Clinical Trial.
PubMed Identifier: 32880602
author list: Tolaney SM, Barroso-Sousa R, Keenan T, Li T, Trippa L, Vaz-Luis I, Wulf G, Spring L, Sinclair NF, Andrews C, Pittenger J, Richardson ET, Dillon D, Lin NU, Overmoyer B, Partridge AH, Van Allen E, Mittendorf EA, Winer EP, Krop IE
published in: JAMA oncology
information resource reference: Effect of Eribulin With or Without Pembrolizumab on Progression-Free Survival for Patients With Hormone Receptor-Positive, ERBB2-Negative Metastatic Breast Cancer: A Randomized Clinical Trial. JAMA Oncol. 2020 10 01; 6(10):1598-1605.
journal title abbreviation: JAMA Oncol
publication date: 2020-10-01T00:00:00
year: 2020
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1283831
type: Authorship
author rank in publication: 11
linked author: Van Allen, Eliezer
linked information resource: Engaging Patients in Precision Oncology: Development and Usability of a Web-Based Patient-Facing Genomic Sequencing Report.

Authorship 1287602
type: Authorship
author rank in publication: 15
linked author: Van Allen, Eliezer
linked information resource: Genomic Resistance Patterns to Second-Generation Androgen Blockade in Paired Tumor Biopsies of Metastatic Castration-Resistant Prostate Cancer.

Engaging Patients in Precision Oncology: Development and Usability of a Web-Based Patient-Facing Genomic Sequencing Report.
PubMed Identifier: 32923887
author list: Solomon IB, McGraw S, Shen J, Albayrak A, Alterovitz G, Davies M, Del Vecchio Fitz C, Freedman RA, Lopez LN, Sholl LM, Van Allen E, Mortimer J, Fakih M, Pal S, Reckamp KL, Yuan Y, Gray SW
published in: JCO precision oncology
information resource reference: Engaging Patients in Precision Oncology: Development and Usability of a Web-Based Patient-Facing Genomic Sequencing Report. JCO Precis Oncol. 2020; 4.
journal title abbreviation: JCO Precis Oncol
publication date: 2020-04-14T00:00:00
year: 2020
type: Academic Article
type: Article
type: Document
type: Information Resource

Genomic Resistance Patterns to Second-Generation Androgen Blockade in Paired Tumor Biopsies of Metastatic Castration-Resistant Prostate Cancer.
PubMed Identifier: 32913968
author list: Han GC, Hwang J, Wankowicz SAM, Zhang Z, Liu D, Cibulskis C, Gaviola GC, Ghazikhanian V, McKay RR, Bubley GJ, Carter SL, Balk SP, Hahn WC, Taplin ME, Van Allen EM
published in: JCO precision oncology
information resource reference: Genomic Resistance Patterns to Second-Generation Androgen Blockade in Paired Tumor Biopsies of Metastatic Castration-Resistant Prostate Cancer. JCO Precis Oncol. 2017; 1.
journal title abbreviation: JCO Precis Oncol
publication date: 2017-12-11T00:00:00
year: 2017
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1295354
type: Authorship
author rank in publication: 35
linked author: Van Allen, Eliezer
linked information resource: Functional Precision Medicine Identifies New Therapeutic Candidates for Medulloblastoma.

Functional Precision Medicine Identifies New Therapeutic Candidates for Medulloblastoma.
PubMed Identifier: 33046443
author list: Rusert JM, Juarez EF, Brabetz S, Jensen J, Garancher A, Chau LQ, Tacheva-Grigorova SK, Wahab S, Udaka YT, Finlay D, Seker-Cin H, Reardon B, Gröbner S, Serrano J, Ecker J, Qi L, Kogiso M, Du Y, Baxter PA, Henderson JJ, Berens ME, Vuori K, Milde T, Cho YJ, Li XN, Olson JM, Reyes I, Snuderl M, Wong TC, Dimmock DP, Nahas SA, Malicki D, Crawford JR, Levy ML, Van Allen EM, Pfister SM, Tamayo P, Kool M, Mesirov JP, Wechsler-Reya RJ
published in: Cancer research
information resource reference: Functional Precision Medicine Identifies New Therapeutic Candidates for Medulloblastoma. Cancer Res. 2020 12 01; 80(23):5393-5407.
journal title abbreviation: Cancer Res
publication date: 2020-10-12T00:00:00
year: 2020
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1302272
type: Authorship
author rank in publication: 27
linked author: Van Allen, Eliezer
linked information resource: Identification of a Synthetic Lethal Relationship between Nucleotide Excision Repair Deficiency and Irofulven Sensitivity in Urothelial Cancer.

Authorship 1306990
type: Authorship
author rank in publication: 16
linked author: Van Allen, Eliezer
linked information resource: Integrated molecular drivers coordinate biological and clinical states in melanoma.

Authorship 1306648
type: Authorship
author rank in publication: 3
linked author: Van Allen, Eliezer
linked information resource: https://connects.catalyst.harvard.edu/Profiles/profile/172390653

Authorship 1304955
type: Authorship
author rank in publication: 26
linked author: Van Allen, Eliezer
linked information resource: Germ Cell Tumor Molecular Heterogeneity Revealed Through Analysis of Primary and Metastasis Pairs.

Authorship 1306238
type: Authorship
author rank in publication: 16
linked author: Van Allen, Eliezer
linked information resource: Detection of Pathogenic Variants With Germline Genetic Testing Using Deep Learning vs Standard Methods in Patients With Prostate Cancer and Melanoma.

Detection of Pathogenic Variants With Germline Genetic Testing Using Deep Learning vs Standard Methods in Patients With Prostate Cancer and Melanoma.
PubMed Identifier: 33201204
author list: AlDubayan SH, Conway JR, Camp SY, Witkowski L, Kofman E, Reardon B, Han S, Moore N, Elmarakeby H, Salari K, Choudhry H, Al-Rubaish AM, Al-Sulaiman AA, Al-Ali AK, Taylor-Weiner A, Van Allen EM
published in: JAMA
information resource reference: Detection of Pathogenic Variants With Germline Genetic Testing Using Deep Learning vs Standard Methods in Patients With Prostate Cancer and Melanoma. JAMA. 2020 11 17; 324(19):1957-1969.
journal title abbreviation: JAMA
publication date: 2020-11-17T00:00:00
year: 2020
type: Academic Article
type: Article
type: Document
type: Information Resource

Identification of a Synthetic Lethal Relationship between Nucleotide Excision Repair Deficiency and Irofulven Sensitivity in Urothelial Cancer.
PubMed Identifier: 33208343
author list: Börcsök J, Sztupinszki Z, Bekele R, Gao SP, Diossy M, Samant AS, Dillon KM, Tisza V, Spisák S, Rusz O, Csabai I, Pappot H, Frazier ZJ, Konieczkowski DJ, Liu D, Vasani N, Rodrigues JA, Solit DB, Hoffman-Censits JH, Plimack ER, Rosenberg JE, Lazaro JB, Taplin ME, Iyer G, Brunak S, Lozsa R, Van Allen EM, Szüts D, Mouw KW, Szallasi Z
published in: Clinical cancer research : an official journal of the American Association for Cancer Research
information resource reference: Identification of a Synthetic Lethal Relationship between Nucleotide Excision Repair Deficiency and Irofulven Sensitivity in Urothelial Cancer. Clin Cancer Res. 2021 04 01; 27(7):2011-2022.
journal title abbreviation: Clin Cancer Res
publication date: 2020-11-18T00:00:00
year: 2020
type: Academic Article
type: Article
type: Document
type: Information Resource

Integrated molecular drivers coordinate biological and clinical states in melanoma.
PubMed Identifier: 33230298
author list: Conway JR, Dietlein F, Taylor-Weiner A, AlDubayan S, Vokes N, Keenan T, Reardon B, He MX, Margolis CA, Weirather JL, Haq R, Schilling B, Stephen Hodi F, Schadendorf D, Liu D, Van Allen EM
published in: Nature genetics
information resource reference: Integrated molecular drivers coordinate biological and clinical states in melanoma. Nat Genet. 2020 12; 52(12):1373-1383.
journal title abbreviation: Nat Genet
publication date: 2020-11-23T00:00:00
year: 2020
type: Academic Article
type: Article
type: Document
type: Information Resource

https://connects.catalyst.harvard.edu/Profiles/profile/172390653
PubMed Identifier: 33218823
author list: Iyer G, Bochner BH, Van Allen EM, Solit DB, Rosenberg JE
published in: European urology
information resource reference: Re: Russell E.N. Becker, Alexa R. Meyer, Aaron Brant, et al. Clinical Restaging and Tumor Sequencing are Inaccurate Indicators of Response to Neoadjuvant Chemotherapy for Muscle-invasive Bladder Cancer. Eur Urol. In press. https://doi.org/10.1016/j.eururo.2020.07.016. Eur Urol. 2021 02; 79(2):e56-e57.
journal title abbreviation: Eur Urol
publication date: 2020-11-18T00:00:00
year: 2020
type: Academic Article
type: Article
type: Document
type: Information Resource
label: Re: Russell E.N. Becker, Alexa R. Meyer, Aaron Brant, et al. Clinical Restaging and Tumor Sequencing are Inaccurate Indicators of Response to Neoadjuvant Chemotherapy for Muscle-invasive Bladder Cancer. Eur Urol. In press. https://doi.org/10.1016/j.eururo.2020.07.016.

Germ Cell Tumor Molecular Heterogeneity Revealed Through Analysis of Primary and Metastasis Pairs.
PubMed Identifier: 33163850
author list: Cheng ML, Donoghue MTA, Audenet F, Wong NC, Pietzak EJ, Bielski CM, Isharwal S, Iyer G, Funt S, Bagrodia A, Bajorin DF, Reuter VE, Eng J, Joseph G, Bourque C, Bromberg M, Ling L, Selcuklu SD, Arcila ME, Tsui DWY, Zehir A, Viale A, Berger MF, Bosl GJ, Sheinfeld J, Van Allen E, Taylor BS, Al-Ahmadie H, Solit DB, Feldman DR
published in: JCO precision oncology
information resource reference: Germ Cell Tumor Molecular Heterogeneity Revealed Through Analysis of Primary and Metastasis Pairs. JCO Precis Oncol. 2020; 4.
journal title abbreviation: JCO Precis Oncol
publication date: 2020-10-30T00:00:00
year: 2020
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1308539
type: Authorship
author rank in publication: 20
linked author: Van Allen, Eliezer
linked information resource: Clinical Efficacy and Molecular Response Correlates of the WEE1 Inhibitor Adavosertib Combined with Cisplatin in Patients with Metastatic Triple-Negative Breast Cancer.

Clinical Efficacy and Molecular Response Correlates of the WEE1 Inhibitor Adavosertib Combined with Cisplatin in Patients with Metastatic Triple-Negative Breast Cancer.
PubMed Identifier: 33257427
author list: Keenan TE, Li T, Vallius T, Guerriero JL, Tayob N, Kochupurakkal B, Davis J, Pastorello R, Tahara RK, Anderson L, Conway J, He MX, Shannon E, Godin RE, Sorger PK, D'Andrea A, Overmoyer B, Winer EP, Mittendorf EA, Van Allen EM, Shapiro GI, Tolaney SM
published in: Clinical cancer research : an official journal of the American Association for Cancer Research
information resource reference: Clinical Efficacy and Molecular Response Correlates of the WEE1 Inhibitor Adavosertib Combined with Cisplatin in Patients with Metastatic Triple-Negative Breast Cancer. Clin Cancer Res. 2021 02 15; 27(4):983-991.
journal title abbreviation: Clin Cancer Res
publication date: 2020-11-30T00:00:00
year: 2020
type: Academic Article
type: Article
type: Document
type: Information Resource

Dissecting the immunogenomic biology of cancer for biomarker development.
PubMed Identifier: 33299070
author list: Van Allen EM, Choueiri TK
published in: Nature reviews. Clinical oncology
information resource reference: Dissecting the immunogenomic biology of cancer for biomarker development. Nat Rev Clin Oncol. 2021 03; 18(3):133-134.
journal title abbreviation: Nat Rev Clin Oncol
publication date: 2021-03-01T00:00:00
year: 2021
type: Academic Article
type: Article
type: Document
type: Information Resource

Predicting immunotherapy response through genomics.
PubMed Identifier: 33307238
author list: Cormedi MCV, Van Allen EM, Colli LM
published in: Current opinion in genetics & development
information resource reference: Predicting immunotherapy response through genomics. Curr Opin Genet Dev. 2021 02; 66:1-9.
journal title abbreviation: Curr Opin Genet Dev
publication date: 2020-12-08T00:00:00
year: 2020
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1310293
type: Authorship
author rank in publication: 2
linked author: Van Allen, Eliezer
linked information resource: Predicting immunotherapy response through genomics.

Authorship 1312115
type: Authorship
author rank in publication: 1
linked author: Van Allen, Eliezer
linked information resource: Dissecting the immunogenomic biology of cancer for biomarker development.

Authorship 1317220
type: Authorship
author rank in publication: 25
linked author: Van Allen, Eliezer
linked information resource: Single-cell RNA sequencing reveals compromised immune microenvironment in precursor stages of multiple myeloma.

Single-cell RNA sequencing reveals compromised immune microenvironment in precursor stages of multiple myeloma.
PubMed Identifier: 33409501
author list: Zavidij O, Haradhvala NJ, Mouhieddine TH, Sklavenitis-Pistofidis R, Cai S, Reidy M, Rahmat M, Flaifel A, Ferland B, Su NK, Agius MP, Park J, Manier S, Bustoros M, Huynh D, Capelletti M, Berrios B, Liu CJ, He MX, Braggio E, Fonseca R, Maruvka YE, Guerriero JL, Goldman M, Van Allen EM, McCarroll SA, Azzi J, Getz G, Ghobrial IM
published in: Nature cancer
information resource reference: Single-cell RNA sequencing reveals compromised immune microenvironment in precursor stages of multiple myeloma. Nat Cancer. 2020 05; 1(5):493-506.
journal title abbreviation: Nat Cancer
publication date: 2020-04-27T00:00:00
year: 2020
type: Academic Article
type: Article
type: Document
type: Information Resource

Beyond conventional immune-checkpoint inhibition - novel immunotherapies for renal cell carcinoma.
PubMed Identifier: 33437048
author list: Braun DA, Bakouny Z, Hirsch L, Flippot R, Van Allen EM, Wu CJ, Choueiri TK
published in: Nature reviews. Clinical oncology
information resource reference: Beyond conventional immune-checkpoint inhibition - novel immunotherapies for renal cell carcinoma. Nat Rev Clin Oncol. 2021 04; 18(4):199-214.
journal title abbreviation: Nat Rev Clin Oncol
publication date: 2021-01-12T00:00:00
year: 2021
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1322573
type: Authorship
author rank in publication: 5
linked author: Van Allen, Eliezer
linked information resource: Beyond conventional immune-checkpoint inhibition - novel immunotherapies for renal cell carcinoma.

Count Me In: Partnering with patients to define the clinical and genomic landscape of rare aggressive sarcomas in children and adults
end date: 2026-08-31
principal investigator name: JANEWAY, KATHERINE A
start date: 2020-09-01
type: Grant
sponsor award id: U2CCA252974

Co-Principal Investigator
type: Researcher Role
researcher role of: Van Allen, Eliezer
contributes to: The Use of Whole-Exome Sequencing to Guide the Care of Cancer Patients

Authorship 1325004
type: Authorship
author rank in publication: 52
linked author: Van Allen, Eliezer
linked information resource: Integrative molecular characterization of sarcomatoid and rhabdoid renal cell carcinoma.

Authorship 1325776
type: Authorship
author rank in publication: 8
linked author: Van Allen, Eliezer
linked information resource: Evaluating the molecular diagnostic yield of joint genotyping-based approach for detecting rare germline pathogenic and putative loss-of-function variants.

Integrative molecular characterization of sarcomatoid and rhabdoid renal cell carcinoma.
PubMed Identifier: 33547292
author list: Bakouny Z, Braun DA, Shukla SA, Pan W, Gao X, Hou Y, Flaifel A, Tang S, Bosma-Moody A, He MX, Vokes N, Nyman J, Xie W, Nassar AH, Abou Alaiwi S, Flippot R, Bouchard G, Steinharter JA, Nuzzo PV, Ficial M, Sant'Angelo M, Forman J, Berchuck JE, Dudani S, Bi K, Park J, Camp S, Sticco-Ivins M, Hirsch L, Baca SC, Wind-Rotolo M, Ross-Macdonald P, Sun M, Lee GM, Chang SL, Wei XX, McGregor BA, Harshman LC, Genovese G, Ellis L, Pomerantz M, Hirsch MS, Freedman ML, Atkins MB, Wu CJ, Ho TH, Linehan WM, McDermott DF, Heng DYC, Viswanathan SR, Signoretti S, Van Allen EM, Choueiri TK
published in: Nature communications
information resource reference: Integrative molecular characterization of sarcomatoid and rhabdoid renal cell carcinoma. Nat Commun. 2021 02 05; 12(1):808.
journal title abbreviation: Nat Commun
publication date: 2021-02-05T00:00:00
year: 2021
type: Academic Article
type: Article
type: Document
type: Information Resource

Evaluating the molecular diagnostic yield of joint genotyping-based approach for detecting rare germline pathogenic and putative loss-of-function variants.
PubMed Identifier: 33531667
author list: Camp SY, Kofman E, Reardon B, Moore ND, Al-Rubaish AM, Aljumaan M, Al-Ali AK, Van Allen EM, Taylor-Weiner A, AlDubayan SH
published in: Genetics in medicine : official journal of the American College of Medical Genetics
information resource reference: Evaluating the molecular diagnostic yield of joint genotyping-based approach for detecting rare germline pathogenic and putative loss-of-function variants. Genet Med. 2021 05; 23(5):918-926.
journal title abbreviation: Genet Med
publication date: 2021-02-02T00:00:00
year: 2021
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1328804
type: Authorship
author rank in publication: 6
linked author: Van Allen, Eliezer
linked information resource: Systematic auditing is essential to debiasing machine learning in biology.

Systematic auditing is essential to debiasing machine learning in biology.
PubMed Identifier: 33568741
author list: Eid FE, Elmarakeby HA, Chan YA, Fornelos N, ElHefnawi M, Van Allen EM, Heath LS, Lage K
published in: Communications biology
information resource reference: Systematic auditing is essential to debiasing machine learning in biology. Commun Biol. 2021 02 10; 4(1):183.
journal title abbreviation: Commun Biol
publication date: 2021-02-10T00:00:00
year: 2021
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1331080
type: Authorship
author rank in publication: 4
linked author: Van Allen, Eliezer
linked information resource: Enrichment of FGFR3-TACC3 Fusions in Patients With Bladder Cancer Who Are Young, Asian, or Have Never Smoked.

Enrichment of FGFR3-TACC3 Fusions in Patients With Bladder Cancer Who Are Young, Asian, or Have Never Smoked.
PubMed Identifier: 33604498
author list: Nassar AH, Lundgren K, Pomerantz M, Van Allen E, Harshman L, Choudhury AD, Preston MA, Steele GS, Mouw KW, Wei XX, McGregor BA, Choueiri TK, Bellmunt J, Kwiatkowski DJ, Sonpavde GP
published in: JCO precision oncology
information resource reference: Enrichment of FGFR3-TACC3 Fusions in Patients With Bladder Cancer Who Are Young, Asian, or Have Never Smoked. JCO Precis Oncol. 2018; 2.
journal title abbreviation: JCO Precis Oncol
publication date: 2018-05-16T00:00:00
year: 2018
type: Academic Article
type: Article
type: Document
type: Information Resource

Transcriptional mediators of treatment resistance in lethal prostate cancer.
PubMed Identifier: 33664492
author list: He MX, Cuoco MS, Crowdis J, Bosma-Moody A, Zhang Z, Bi K, Kanodia A, Su MJ, Ku SY, Garcia MM, Sweet AR, Rodman C, DelloStritto L, Silver R, Steinharter J, Shah P, Izar B, Walk NC, Burke KP, Bakouny Z, Tewari AK, Liu D, Camp SY, Vokes NI, Salari K, Park J, Vigneau S, Fong L, Russo JW, Yuan X, Balk SP, Beltran H, Rozenblatt-Rosen O, Regev A, Rotem A, Taplin ME, Van Allen EM
published in: Nature medicine
information resource reference: Transcriptional mediators of treatment resistance in lethal prostate cancer. Nat Med. 2021 03; 27(3):426-433.
journal title abbreviation: Nat Med
publication date: 2021-03-04T00:00:00
year: 2021
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1335873
type: Authorship
author rank in publication: 37
linked author: Van Allen, Eliezer
linked information resource: Transcriptional mediators of treatment resistance in lethal prostate cancer.

Tumor and immune reprogramming during immunotherapy in advanced renal cell carcinoma.
PubMed Identifier: 33711272
author list: Bi K, He MX, Bakouny Z, Kanodia A, Napolitano S, Wu J, Grimaldi G, Braun DA, Cuoco MS, Mayorga A, DelloStritto L, Bouchard G, Steinharter J, Tewari AK, Vokes NI, Shannon E, Sun M, Park J, Chang SL, McGregor BA, Haq R, Denize T, Signoretti S, Guerriero JL, Vigneau S, Rozenblatt-Rosen O, Rotem A, Regev A, Choueiri TK, Van Allen EM
published in: Cancer cell
information resource reference: Tumor and immune reprogramming during immunotherapy in advanced renal cell carcinoma. Cancer Cell. 2021 05 10; 39(5):649-661.e5.
journal title abbreviation: Cancer Cell
publication date: 2021-03-11T00:00:00
year: 2021
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1338016
type: Authorship
author rank in publication: 30
linked author: Van Allen, Eliezer
linked information resource: Tumor and immune reprogramming during immunotherapy in advanced renal cell carcinoma.

Authorship 1337517
type: Authorship
author rank in publication: 29
linked author: Van Allen, Eliezer
linked information resource: Intrinsic Immunogenicity of Small Cell Lung Carcinoma Revealed by Its Cellular Plasticity.

Intrinsic Immunogenicity of Small Cell Lung Carcinoma Revealed by Its Cellular Plasticity.
PubMed Identifier: 33707236
author list: Mahadevan NR, Knelson EH, Wolff JO, Vajdi A, Saigí M, Campisi M, Hong D, Thai TC, Piel B, Han S, Reinhold BB, Duke-Cohan JS, Poitras MJ, Taus LJ, Lizotte PH, Portell A, Quadros V, Santucci AD, Murayama T, Cañadas I, Kitajima S, Akitsu A, Fridrikh M, Watanabe H, Reardon B, Gokhale PC, Paweletz CP, Awad MM, Van Allen EM, Lako A, Wang XT, Chen B, Hong F, Sholl LM, Tolstorukov MY, Pfaff K, Jänne PA, Gjini E, Edwards R, Rodig S, Reinherz EL, Oser MG, Barbie DA
published in: Cancer discovery
information resource reference: Intrinsic Immunogenicity of Small Cell Lung Carcinoma Revealed by Its Cellular Plasticity. Cancer Discov. 2021 08; 11(8):1952-1969.
journal title abbreviation: Cancer Discov
publication date: 2021-03-11T00:00:00
year: 2021
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1347668
type: Authorship
author rank in publication: 9
linked author: Van Allen, Eliezer
linked information resource: Impact of Pathogenic Germline DNA Damage Repair alterations on Response to Intense Neoadjuvant Androgen Deprivation Therapy in High-risk Localized Prostate Cancer.

Authorship 1348634
type: Authorship
author rank in publication: 12
linked author: Van Allen, Eliezer
linked information resource: Phase II Multicenter Study of Enzalutamide in Metastatic Castration-Resistant Prostate Cancer to Identify Mechanisms Driving Resistance.

Phase II Multicenter Study of Enzalutamide in Metastatic Castration-Resistant Prostate Cancer to Identify Mechanisms Driving Resistance.
PubMed Identifier: 33849963
author list: McKay RR, Kwak L, Crowdis JP, Sperger JM, Zhao SG, Xie W, Werner L, Lis RT, Zhang Z, Wei XX, Lang JM, Van Allen EM, Bhatt RS, Yu EY, Nelson PS, Bubley GJ, Montgomery RB, Taplin ME
published in: Clinical cancer research : an official journal of the American Association for Cancer Research
information resource reference: Phase II Multicenter Study of Enzalutamide in Metastatic Castration-Resistant Prostate Cancer to Identify Mechanisms Driving Resistance. Clin Cancer Res. 2021 07 01; 27(13):3610-3619.
journal title abbreviation: Clin Cancer Res
publication date: 2021-04-13T00:00:00
year: 2021
type: Academic Article
type: Article
type: Document
type: Information Resource

Impact of Pathogenic Germline DNA Damage Repair alterations on Response to Intense Neoadjuvant Androgen Deprivation Therapy in High-risk Localized Prostate Cancer.
PubMed Identifier: 33888356
author list: Berchuck JE, Zhang Z, Silver R, Kwak L, Xie W, Lee GM, Freedman ML, Kibel AS, Van Allen EM, McKay RR, Taplin ME
published in: European urology
information resource reference: Impact of Pathogenic Germline DNA Damage Repair alterations on Response to Intense Neoadjuvant Androgen Deprivation Therapy in High-risk Localized Prostate Cancer. Eur Urol. 2021 09; 80(3):295-303.
journal title abbreviation: Eur Urol
publication date: 2021-04-19T00:00:00
year: 2021
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1352955
type: Authorship
author rank in publication: 34
linked author: Van Allen, Eliezer
linked information resource: Evolution of delayed resistance to immunotherapy in a melanoma responder.

Evolution of delayed resistance to immunotherapy in a melanoma responder.
PubMed Identifier: 33941922
author list: Liu D, Lin JR, Robitschek EJ, Kasumova GG, Heyde A, Shi A, Kraya A, Zhang G, Moll T, Frederick DT, Chen YA, Wang S, Schapiro D, Ho LL, Bi K, Sahu A, Mei S, Miao B, Sharova T, Alvarez-Breckenridge C, Stocking JH, Kim T, Fadden R, Lawrence D, Hoang MP, Cahill DP, Malehmir M, Nowak MA, Brastianos PK, Lian CG, Ruppin E, Izar B, Herlyn M, Van Allen EM, Nathanson K, Flaherty KT, Sullivan RJ, Kellis M, Sorger PK, Boland GM
published in: Nature medicine
information resource reference: Evolution of delayed resistance to immunotherapy in a melanoma responder. Nat Med. 2021 06; 27(6):985-992.
journal title abbreviation: Nat Med
publication date: 2021-05-03T00:00:00
year: 2021
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1361981
type: Authorship
author rank in publication: 7
linked author: Van Allen, Eliezer
linked information resource: Clinical Inflection Point Detection on the Basis of EHR Data to Identify Clinical Trial-Ready Patients With Cancer.

Authorship 1362650
type: Authorship
author rank in publication: 22
linked author: Van Allen, Eliezer
linked information resource: Gene Fusions Create Partner and Collateral Dependencies Essential to Cancer Cell Survival.

Gene Fusions Create Partner and Collateral Dependencies Essential to Cancer Cell Survival.
PubMed Identifier: 34099491
author list: Gillani R, Seong BKA, Crowdis J, Conway JR, Dharia NV, Alimohamed S, Haas BJ, Han K, Park J, Dietlein F, He MX, Imamovic A, Ma C, Bassik MC, Boehm JS, Vazquez F, Gusev A, Liu D, Janeway KA, McFarland JM, Stegmaier K, Van Allen EM
published in: Cancer research
information resource reference: Gene Fusions Create Partner and Collateral Dependencies Essential to Cancer Cell Survival. Cancer Res. 2021 08 01; 81(15):3971-3984.
journal title abbreviation: Cancer Res
publication date: 2021-06-07T00:00:00
year: 2021
type: Academic Article
type: Article
type: Document
type: Information Resource

Clinical Inflection Point Detection on the Basis of EHR Data to Identify Clinical Trial-Ready Patients With Cancer.
PubMed Identifier: 34097438
author list: Kehl KL, Groha S, Lepisto EM, Elmarakeby H, Lindsay J, Gusev A, Van Allen EM, Hassett MJ, Schrag D
published in: JCO clinical cancer informatics
information resource reference: Clinical Inflection Point Detection on the Basis of EHR Data to Identify Clinical Trial-Ready Patients With Cancer. JCO Clin Cancer Inform. 2021 06; 5:622-630.
journal title abbreviation: JCO Clin Cancer Inform
publication date: 2021-06-01T00:00:00
year: 2021
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1363814
type: Authorship
author rank in publication: 8
linked author: Van Allen, Eliezer
linked information resource: Transcriptional profiling of primary prostate tumor in metastatic hormone-sensitive prostate cancer and association with clinical outcomes: correlative analysis of the E3805 CHAARTED trial.

Authorship 1364127
type: Authorship
author rank in publication: 12
linked author: Van Allen, Eliezer
linked information resource: Discovery and Features of an Alkylating Signature in Colorectal Cancer.

Discovery and Features of an Alkylating Signature in Colorectal Cancer.
PubMed Identifier: 34140290
author list: Gurjao C, Zhong R, Haruki K, Li YY, Spurr LF, Lee-Six H, Reardon B, Ugai T, Zhang X, Cherniack AD, Song M, Van Allen EM, Meyerhardt JA, Nowak JA, Giovannucci EL, Fuchs CS, Wu K, Ogino S, Giannakis M
published in: Cancer discovery
information resource reference: Discovery and Features of an Alkylating Signature in Colorectal Cancer. Cancer Discov. 2021 10; 11(10):2446-2455.
journal title abbreviation: Cancer Discov
publication date: 2021-06-17T00:00:00
year: 2021
type: Academic Article
type: Article
type: Document
type: Information Resource

Transcriptional profiling of primary prostate tumor in metastatic hormone-sensitive prostate cancer and association with clinical outcomes: correlative analysis of the E3805 CHAARTED trial.
PubMed Identifier: 34129855
author list: Hamid AA, Huang HC, Wang V, Chen YH, Feng F, Den R, Attard G, Van Allen EM, Tran PT, Spratt DE, Dittamore R, Davicioni E, Liu G, DiPaola R, Carducci MA, Sweeney CJ
published in: Annals of oncology : official journal of the European Society for Medical Oncology
information resource reference: Transcriptional profiling of primary prostate tumor in metastatic hormone-sensitive prostate cancer and association with clinical outcomes: correlative analysis of the E3805 CHAARTED trial. Ann Oncol. 2021 09; 32(9):1157-1166.
journal title abbreviation: Ann Oncol
publication date: 2021-06-12T00:00:00
year: 2021
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1375770
type: Authorship
author rank in publication: 21
linked author: Van Allen, Eliezer
linked information resource: Accelerating precision medicine in metastatic prostate cancer.

Accelerating precision medicine in metastatic prostate cancer.
PubMed Identifier: 34258585
author list: Mateo J, McKay R, Abida W, Aggarwal R, Alumkal J, Alva A, Feng F, Gao X, Graff J, Hussain M, Karzai F, Montgomery B, Oh W, Patel V, Rathkopf D, Rettig M, Schultz N, Smith M, Solit D, Sternberg C, Van Allen E, VanderWeele D, Vinson J, Soule HR, Chinnaiyan A, Small E, Simons JW, Dahut W, Miyahira AK, Beltran H
published in: Nature cancer
information resource reference: Accelerating precision medicine in metastatic prostate cancer. Nat Cancer. 2020 11; 1(11):1041-1053.
journal title abbreviation: Nat Cancer
publication date: 2020-11-17T00:00:00
year: 2020
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1388842
type: Authorship
author rank in publication: 14
linked author: Van Allen, Eliezer
linked information resource: Nivolumab in combination with cabozantinib for metastatic triple-negative breast cancer: a phase II and biomarker study.

Nivolumab in combination with cabozantinib for metastatic triple-negative breast cancer: a phase II and biomarker study.
PubMed Identifier: 34433812
author list: Barroso-Sousa R, Keenan TE, Li T, Tayob N, Trippa L, Pastorello RG, Richardson Iii ET, Dillon D, Amoozgar Z, Overmoyer B, Schnitt SJ, Winer EP, Mittendorf EA, Van Allen E, Duda DG, Tolaney SM
published in: NPJ breast cancer
information resource reference: Nivolumab in combination with cabozantinib for metastatic triple-negative breast cancer: a phase II and biomarker study. NPJ Breast Cancer. 2021 Aug 25; 7(1):110.
journal title abbreviation: NPJ Breast Cancer
publication date: 2021-08-25T00:00:00
year: 2021
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1394783
type: Authorship
author rank in publication: 20
linked author: Van Allen, Eliezer
linked information resource: Molecular features of exceptional response to neoadjuvant anti-androgen therapy in high-risk localized prostate cancer.

Molecular features of exceptional response to neoadjuvant anti-androgen therapy in high-risk localized prostate cancer.
PubMed Identifier: 34496240
author list: Tewari AK, Cheung ATM, Crowdis J, Conway JR, Camp SY, Wankowicz SA, Livitz DG, Park J, Lis RT, Bosma-Moody A, He MX, AlDubayan SH, Zhang Z, McKay RR, Leshchiner I, Brown M, Balk SP, Getz G, Taplin ME, Van Allen EM
published in: Cell reports
information resource reference: Molecular features of exceptional response to neoadjuvant anti-androgen therapy in high-risk localized prostate cancer. Cell Rep. 2021 09 07; 36(10):109665.
journal title abbreviation: Cell Rep
publication date: 2021-09-07T00:00:00
year: 2021
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1396331
type: Authorship
author rank in publication: 28
linked author: Van Allen, Eliezer
linked information resource: Molecular correlates of response to eribulin and pembrolizumab in hormone receptor-positive metastatic breast cancer.

Authorship 1396465
type: Authorship
author rank in publication: 17
linked author: Van Allen, Eliezer
linked information resource: RAF1 amplification drives a subset of bladder tumors and confers sensitivity to MAPK-directed therapeutics.

Biologically informed deep neural network for prostate cancer discovery.
PubMed Identifier: 34552244
author list: Elmarakeby HA, Hwang J, Arafeh R, Crowdis J, Gang S, Liu D, AlDubayan SH, Salari K, Kregel S, Richter C, Arnoff TE, Park J, Hahn WC, Van Allen EM
published in: Nature
information resource reference: Biologically informed deep neural network for prostate cancer discovery. Nature. 2021 10; 598(7880):348-352.
journal title abbreviation: Nature
publication date: 2021-09-22T00:00:00
year: 2021
type: Academic Article
type: Article
type: Document
type: Information Resource

Molecular correlates of response to eribulin and pembrolizumab in hormone receptor-positive metastatic breast cancer.
PubMed Identifier: 34548479
author list: Keenan TE, Guerriero JL, Barroso-Sousa R, Li T, O'Meara T, Giobbie-Hurder A, Tayob N, Hu J, Severgnini M, Agudo J, Vaz-Luis I, Anderson L, Attaya V, Park J, Conway J, He MX, Reardon B, Shannon E, Wulf G, Spring LM, Jeselsohn R, Krop I, Lin NU, Partridge A, Winer EP, Mittendorf EA, Liu D, Van Allen EM, Tolaney SM
published in: Nature communications
information resource reference: Molecular correlates of response to eribulin and pembrolizumab in hormone receptor-positive metastatic breast cancer. Nat Commun. 2021 09 21; 12(1):5563.
journal title abbreviation: Nat Commun
publication date: 2021-09-21T00:00:00
year: 2021
type: Academic Article
type: Article
type: Document
type: Information Resource

RAF1 amplification drives a subset of bladder tumors and confers sensitivity to MAPK-directed therapeutics.
PubMed Identifier: 34554931
author list: Bekele RT, Samant AS, Nassar AH, So J, Garcia EP, Curran CR, Hwang JH, Mayhew DL, Nag A, Thorner AR, Börcsök J, Sztupinszki Z, Pan CX, Bellmunt J, Kwiatkowski DJ, Sonpavde GP, Van Allen EM, Mouw KW
published in: The Journal of clinical investigation
information resource reference: RAF1 amplification drives a subset of bladder tumors and confers sensitivity to MAPK-directed therapeutics. J Clin Invest. 2021 11 15; 131(22).
journal title abbreviation: J Clin Invest
publication date: 2021-11-15T00:00:00
year: 2021
type: Academic Article
type: Article
type: Document
type: Information Resource

Subtype heterogeneity and epigenetic convergence in neuroendocrine prostate cancer.
PubMed Identifier: 34599169
author list: Cejas P, Xie Y, Font-Tello A, Lim K, Syamala S, Qiu X, Tewari AK, Shah N, Nguyen HM, Patel RA, Brown L, Coleman I, Hackeng WM, Brosens L, Dreijerink KMA, Ellis L, Alaiwi SA, Seo JH, Baca S, Beltran H, Khani F, Pomerantz M, Dall'Agnese A, Crowdis J, Van Allen EM, Bellmunt J, Morrisey C, Nelson PS, DeCaprio J, Farago A, Dyson N, Drapkin B, Liu XS, Freedman M, Haffner MC, Corey E, Brown M, Long HW
published in: Nature communications
information resource reference: Subtype heterogeneity and epigenetic convergence in neuroendocrine prostate cancer. Nat Commun. 2021 10 01; 12(1):5775.
journal title abbreviation: Nat Commun
publication date: 2021-10-01T00:00:00
year: 2021
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 189810
type: Authorship
author rank in publication: 1
linked author: Van Allen, Eliezer
linked information resource: The paradox of positive thinking.

Authorship 1399277
type: Authorship
author rank in publication: 25
linked author: Van Allen, Eliezer
linked information resource: Subtype heterogeneity and epigenetic convergence in neuroendocrine prostate cancer.

Authorship 1400213
type: Authorship
author rank in publication: 14
linked author: Van Allen, Eliezer
linked information resource: Biologically informed deep neural network for prostate cancer discovery.

Racial and Ethnic Disparities Among Participants in Precision Oncology Clinical Studies.
PubMed Identifier: 34748007
author list: Aldrighetti CM, Niemierko A, Van Allen E, Willers H, Kamran SC
published in: JAMA network open
information resource reference: Racial and Ethnic Disparities Among Participants in Precision Oncology Clinical Studies. JAMA Netw Open. 2021 11 01; 4(11):e2133205.
journal title abbreviation: JAMA Netw Open
publication date: 2021-11-01T00:00:00
year: 2021
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1415751
type: Authorship
author rank in publication: 3
linked author: Van Allen, Eliezer
linked information resource: Racial and Ethnic Disparities Among Participants in Precision Oncology Clinical Studies.

Authorship 1418457
type: Authorship
author rank in publication: 8
linked author: Van Allen, Eliezer
linked information resource: Building Tools for Machine Learning and Artificial Intelligence in Cancer Research: Best Practices and a Case Study with the PathML Toolkit for Computational Pathology.

Authorship 1418331
type: Authorship
author rank in publication: 13
linked author: Van Allen, Eliezer
linked information resource: Genomic attributes of homology-directed DNA repair deficiency in metastatic prostate cancer.

Authorship 1418377
type: Authorship
author rank in publication: 20
linked author: Van Allen, Eliezer
linked information resource: Inherited TP53 Variants and Risk of Prostate Cancer.

Building Tools for Machine Learning and Artificial Intelligence in Cancer Research: Best Practices and a Case Study with the PathML Toolkit for Computational Pathology.
PubMed Identifier: 34880124
author list: Rosenthal J, Carelli R, Omar M, Brundage D, Halbert E, Nyman J, Hari SN, Van Allen EM, Marchionni L, Umeton R, Loda M
published in: Molecular cancer research : MCR
information resource reference: Building Tools for Machine Learning and Artificial Intelligence in Cancer Research: Best Practices and a Case Study with the PathML Toolkit for Computational Pathology. Mol Cancer Res. 2022 02; 20(2):202-206.
journal title abbreviation: Mol Cancer Res
publication date: 2021-12-08T00:00:00
year: 2021
type: Academic Article
type: Article
type: Document
type: Information Resource

Inherited TP53 Variants and Risk of Prostate Cancer.
PubMed Identifier: 34863587
author list: Maxwell KN, Cheng HH, Powers J, Gulati R, Ledet EM, Morrison C, Le A, Hausler R, Stopfer J, Hyman S, Kohlmann W, Naumer A, Vagher J, Greenberg SE, Naylor L, Laurino M, Konnick EQ, Shirts BH, AlDubayan SH, Van Allen EM, Nguyen B, Vijai J, Abida W, Carlo MI, Dubard-Gault M, Lee DJ, Maese LD, Mandelker D, Montgomery B, Morris MJ, Nicolosi P, Nussbaum RL, Schwartz LE, Stadler Z, Garber JE, Offit K, Schiffman JD, Nelson PS, Sartor O, Walsh MF, Pritchard CC
published in: European urology
information resource reference: Inherited TP53 Variants and Risk of Prostate Cancer. Eur Urol. 2022 Mar; 81(3):243-250.
journal title abbreviation: Eur Urol
publication date: 2021-12-01T00:00:00
year: 2021
type: Academic Article
type: Article
type: Document
type: Information Resource

Genomic attributes of homology-directed DNA repair deficiency in metastatic prostate cancer.
PubMed Identifier: 34877933
author list: De Sarkar N, Dasgupta S, Chatterjee P, Coleman I, Ha G, Ang LS, Kohlbrenner EA, Frank SB, Nunez TA, Salipante SJ, Corey E, Morrissey C, Van Allen E, Schweizer MT, Haffner MC, Patel R, Hanratty B, Lucas JM, Dumpit RF, Pritchard CC, Montgomery RB, Nelson PS
published in: JCI insight
information resource reference: Genomic attributes of homology-directed DNA repair deficiency in metastatic prostate cancer. JCI Insight. 2021 12 08; 6(23).
journal title abbreviation: JCI Insight
publication date: 2021-12-08T00:00:00
year: 2021
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1419658
type: Authorship
author rank in publication: 8
linked author: Van Allen, Eliezer
linked information resource: Artificial intelligence-aided clinical annotation of a large multi-cancer genomic dataset.

Artificial intelligence-aided clinical annotation of a large multi-cancer genomic dataset.
PubMed Identifier: 34911934
author list: Kehl KL, Xu W, Gusev A, Bakouny Z, Choueiri TK, Riaz IB, Elmarakeby H, Van Allen EM, Schrag D
published in: Nature communications
information resource reference: Artificial intelligence-aided clinical annotation of a large multi-cancer genomic dataset. Nat Commun. 2021 12 15; 12(1):7304.
journal title abbreviation: Nat Commun
publication date: 2021-12-15T00:00:00
year: 2021
type: Academic Article
type: Article
type: Document
type: Information Resource

Integrative clinical and molecular characterization of translocation renal cell carcinoma.
PubMed Identifier: 34986355
author list: Bakouny Z, Sadagopan A, Ravi P, Metaferia NY, Li J, AbuHammad S, Tang S, Denize T, Garner ER, Gao X, Braun DA, Hirsch L, Steinharter JA, Bouchard G, Walton E, West D, Labaki C, Dudani S, Gan CL, Sethunath V, Carvalho FLF, Imamovic A, Ricker C, Vokes NI, Nyman J, Berchuck JE, Park J, Hirsch MS, Haq R, Mary Lee GS, McGregor BA, Chang SL, Feldman AS, Wu CJ, McDermott DF, Heng DYC, Signoretti S, Van Allen EM, Choueiri TK, Viswanathan SR
published in: Cell reports
information resource reference: Integrative clinical and molecular characterization of translocation renal cell carcinoma. Cell Rep. 2022 01 04; 38(1):110190.
journal title abbreviation: Cell Rep
publication date: 2022-01-04T00:00:00
year: 2022
type: Academic Article
type: Article
type: Document
type: Information Resource

Tumor Mutations Across Racial Groups in a Real-World Data Registry.
PubMed Identifier: 34994651
author list: Kamran SC, Xie J, Cheung ATM, Mavura MY, Song H, Palapattu EL, Madej J, Gusev A, Van Allen EM, Huang FW
published in: JCO precision oncology
information resource reference: Tumor Mutations Across Racial Groups in a Real-World Data Registry. JCO Precis Oncol. 2021 11; 5:1654-1658.
journal title abbreviation: JCO Precis Oncol
publication date: 2021-11-01T00:00:00
year: 2021
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1421834
type: Authorship
author rank in publication: 38
linked author: Van Allen, Eliezer
linked information resource: Integrative clinical and molecular characterization of translocation renal cell carcinoma.

Authorship 1423622
type: Authorship
author rank in publication: 13
linked author: Van Allen, Eliezer
linked information resource: Genomic Features of Muscle-invasive Bladder Cancer Arising After Prostate Radiotherapy.

Authorship 1421925
type: Authorship
author rank in publication: 9
linked author: Van Allen, Eliezer
linked information resource: Tumor Mutations Across Racial Groups in a Real-World Data Registry.

Genomic Features of Muscle-invasive Bladder Cancer Arising After Prostate Radiotherapy.
PubMed Identifier: 34953602
author list: Mossanen M, Carvalho FLF, Muralidhar V, Preston MA, Reardon B, Conway JR, Curran C, Freeman D, Sha S, Sonpavde G, Hirsch M, Kibel AS, Van Allen EM, Mouw KW
published in: European urology
information resource reference: Genomic Features of Muscle-invasive Bladder Cancer Arising After Prostate Radiotherapy. Eur Urol. 2022 05; 81(5):466-473.
journal title abbreviation: Eur Urol
publication date: 2021-12-23T00:00:00
year: 2021
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1428190
type: Authorship
author rank in publication: 16
linked author: Van Allen, Eliezer
linked information resource: Implementation of a prostate cancer-specific targeted sequencing panel for credentialing of patient-derived cell lines and genomic characterization of patient samples.

Implementation of a prostate cancer-specific targeted sequencing panel for credentialing of patient-derived cell lines and genomic characterization of patient samples.
PubMed Identifier: 35084050
author list: Stover EH, Oh C, Keskula P, Choudhury AD, Tseng YY, Adalsteinsson VA, Lohr JG, Thorner AR, Ducar M, Kryukov GV, Ha G, Rosenberg M, Freeman SS, Zhang Z, Wu X, Van Allen EM, Takeda DY, Loda M, Wu CL, Taplin ME, Garraway LA, Boehm JS, Huang FW
published in: The Prostate
information resource reference: Implementation of a prostate cancer-specific targeted sequencing panel for credentialing of patient-derived cell lines and genomic characterization of patient samples. Prostate. 2022 04; 82(5):584-597.
journal title abbreviation: Prostate
publication date: 2022-01-27T00:00:00
year: 2022
type: Academic Article
type: Article
type: Document
type: Information Resource

Integrating molecular profiles into clinical frameworks through the Molecular Oncology Almanac to prospectively guide precision oncology.
PubMed Identifier: 35121878
author list: Reardon B, Moore ND, Moore NS, Kofman E, AlDubayan SH, Cheung ATM, Conway J, Elmarakeby H, Imamovic A, Kamran SC, Keenan T, Keliher D, Konieczkowski DJ, Liu D, Mouw KW, Park J, Vokes NI, Dietlein F, Van Allen EM
published in: Nature cancer
information resource reference: Integrating molecular profiles into clinical frameworks through the Molecular Oncology Almanac to prospectively guide precision oncology. Nat Cancer. 2021 10; 2(10):1102-1112.
journal title abbreviation: Nat Cancer
publication date: 2021-09-30T00:00:00
year: 2021
type: Academic Article
type: Article
type: Document
type: Information Resource

Towards a Better Understanding of Antibody-Drug Conjugates in Urothelial Carcinoma.
PubMed Identifier: 35105532
author list: Labaki C, Bakouny Z, Sonpavde G, Choueiri TK, Van Allen EM
published in: European urology oncology
information resource reference: Towards a Better Understanding of Antibody-Drug Conjugates in Urothelial Carcinoma. Eur Urol Oncol. 2022 12; 5(6):719-721.
journal title abbreviation: Eur Urol Oncol
publication date: 2022-01-31T00:00:00
year: 2022
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1431120
type: Authorship
author rank in publication: 13
linked author: Van Allen, Eliezer
linked information resource: Autocrine Canonical Wnt Signaling Primes Noncanonical Signaling through ROR1 in Metastatic Castration-Resistant Prostate Cancer.

Authorship 1430066
type: Authorship
author rank in publication: 5
linked author: Van Allen, Eliezer
linked information resource: Towards a Better Understanding of Antibody-Drug Conjugates in Urothelial Carcinoma.

Authorship 1430162
type: Authorship
author rank in publication: 19
linked author: Van Allen, Eliezer
linked information resource: Integrating molecular profiles into clinical frameworks through the Molecular Oncology Almanac to prospectively guide precision oncology.

Authorship 1431188
type: Authorship
author rank in publication: 2
linked author: Van Allen, Eliezer
linked information resource: Linking a Trio of Molecular Features in Clear-Cell Renal Cell Carcinoma.

Autocrine Canonical Wnt Signaling Primes Noncanonical Signaling through ROR1 in Metastatic Castration-Resistant Prostate Cancer.
PubMed Identifier: 35131873
author list: Ma F, Arai S, Wang K, Calagua C, Yuan AR, Poluben L, Gu Z, Russo JW, Einstein DJ, Ye H, He MX, Liu Y, Van Allen E, Sowalsky AG, Bhasin MK, Yuan X, Balk SP
published in: Cancer research
information resource reference: Autocrine Canonical Wnt Signaling Primes Noncanonical Signaling through ROR1 in Metastatic Castration-Resistant Prostate Cancer. Cancer Res. 2022 04 15; 82(8):1518-1533.
journal title abbreviation: Cancer Res
publication date: 2022-04-15T00:00:00
year: 2022
type: Academic Article
type: Article
type: Document
type: Information Resource

Linking a Trio of Molecular Features in Clear-Cell Renal Cell Carcinoma.
PubMed Identifier: 35131809
author list: Labaki C, Van Allen EM, Choueiri TK
published in: Cancer immunology research
information resource reference: Linking a Trio of Molecular Features in Clear-Cell Renal Cell Carcinoma. Cancer Immunol Res. 2022 03 01; 10(3):274.
journal title abbreviation: Cancer Immunol Res
publication date: 2022-03-01T00:00:00
year: 2022
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1435263
type: Authorship
author rank in publication: 10
linked author: Van Allen, Eliezer
linked information resource: Concurrent TP53 Mutations Facilitate Resistance Evolution in EGFR-Mutant Lung Adenocarcinoma.

Authorship 1438347
type: Authorship
author rank in publication: 5
linked author: Van Allen, Eliezer
linked information resource: Computed Tomography Texture Analysis for Predicting Clinical Outcomes in Patients With Metastatic Renal Cell Carcinoma Treated With Immune Checkpoint Inhibitors.

Concurrent TP53 Mutations Facilitate Resistance Evolution in EGFR-Mutant Lung Adenocarcinoma.
PubMed Identifier: 35331964
author list: Vokes NI, Chambers E, Nguyen T, Coolidge A, Lydon CA, Le X, Sholl L, Heymach JV, Nishino M, Van Allen EM, Jänne PA
published in: Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer
information resource reference: Concurrent TP53 Mutations Facilitate Resistance Evolution in EGFR-Mutant Lung Adenocarcinoma. J Thorac Oncol. 2022 06; 17(6):779-792.
journal title abbreviation: J Thorac Oncol
publication date: 2022-03-21T00:00:00
year: 2022
type: Academic Article
type: Article
type: Document
type: Information Resource

Computed Tomography Texture Analysis for Predicting Clinical Outcomes in Patients With Metastatic Renal Cell Carcinoma Treated With Immune Checkpoint Inhibitors.
PubMed Identifier: 35348767
author list: Park HJ, Qin L, Bakouny Z, Krajewski KM, Van Allen EM, Choueiri TK, Shinagare AB
published in: The oncologist
information resource reference: Computed Tomography Texture Analysis for Predicting Clinical Outcomes in Patients With Metastatic Renal Cell Carcinoma Treated With Immune Checkpoint Inhibitors. Oncologist. 2022 05 06; 27(5):389-397.
journal title abbreviation: Oncologist
publication date: 2022-05-06T00:00:00
year: 2022
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1444926
type: Authorship
author rank in publication: 17
linked author: Van Allen, Eliezer
linked information resource: Germline predisposition to pediatric Ewing sarcoma is characterized by inherited pathogenic variants in DNA damage repair genes.

Authorship 1446592
type: Authorship
author rank in publication: 10
linked author: Van Allen, Eliezer
linked information resource: Genome-wide analysis of somatic noncoding mutation patterns in cancer.

Authorship 1447851
type: Authorship
author rank in publication: 12
linked author: Van Allen, Eliezer
linked information resource: Insights into Immune Escape During Tumor Evolution and Response to Immunotherapy Using a Rat Model of Breast Cancer.

Germline predisposition to pediatric Ewing sarcoma is characterized by inherited pathogenic variants in DNA damage repair genes.
PubMed Identifier: 35512711
author list: Gillani R, Camp SY, Han S, Jones JK, Chu H, O'Brien S, Young EL, Hayes L, Mitchell G, Fowler T, Gusev A, Kamihara J, Janeway KA, Schiffman JD, Crompton BD, AlDubayan SH, Van Allen EM
published in: American journal of human genetics
information resource reference: Germline predisposition to pediatric Ewing sarcoma is characterized by inherited pathogenic variants in DNA damage repair genes. Am J Hum Genet. 2022 06 02; 109(6):1026-1037.
journal title abbreviation: Am J Hum Genet
publication date: 2022-05-04T00:00:00
year: 2022
type: Academic Article
type: Article
type: Document
type: Information Resource

Genome-wide analysis of somatic noncoding mutation patterns in cancer.
PubMed Identifier: 35389777
author list: Dietlein F, Wang AB, Fagre C, Tang A, Besselink NJM, Cuppen E, Li C, Sunyaev SR, Neal JT, Van Allen EM
published in: Science (New York, N.Y.)
information resource reference: Genome-wide analysis of somatic noncoding mutation patterns in cancer. Science. 2022 04 08; 376(6589):eabg5601.
journal title abbreviation: Science
publication date: 2022-04-08T00:00:00
year: 2022
type: Academic Article
type: Article
type: Document
type: Information Resource

Insights into Immune Escape During Tumor Evolution and Response to Immunotherapy Using a Rat Model of Breast Cancer.
PubMed Identifier: 35446942
author list: Gil Del Alcazar CR, Trinh A, Aleckovic M, Rojas Jimenez E, Harper NW, Oliphant MUJ, Xie S, Krop ED, Lulseged B, Murphy KC, Keenan TE, Van Allen EM, Tolaney SM, Freeman GJ, Dillon DA, Muthuswamy SK, Polyak K
published in: Cancer immunology research
information resource reference: Insights into Immune Escape During Tumor Evolution and Response to Immunotherapy Using a Rat Model of Breast Cancer. Cancer Immunol Res. 2022 06 03; 10(6):680-697.
journal title abbreviation: Cancer Immunol Res
publication date: 2022-06-03T00:00:00
year: 2022
type: Academic Article
type: Article
type: Document
type: Information Resource

CREB5 reprograms FOXA1 nuclear interactions to promote resistance to androgen receptor-targeting therapies.
PubMed Identifier: 35550030
author list: Hwang JH, Arafeh R, Seo JH, Baca SC, Ludwig M, Arnoff TE, Sawyer L, Richter C, Tape S, Bergom HE, McSweeney S, Rennhack JP, Klingenberg SA, Cheung ATM, Kwon J, So J, Kregel S, Van Allen EM, Drake JM, Freedman ML, Hahn WC
published in: eLife
information resource reference: CREB5 reprograms FOXA1 nuclear interactions to promote resistance to androgen receptor-targeting therapies. Elife. 2022 05 12; 11.
journal title abbreviation: Elife
publication date: 2022-05-12T00:00:00
year: 2022
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1452807
type: Authorship
author rank in publication: 18
linked author: Van Allen, Eliezer
linked information resource: CREB5 reprograms FOXA1 nuclear interactions to promote resistance to androgen receptor-targeting therapies.

Association of High Tumor Mutation Burden in Non-Small Cell Lung Cancers With Increased Immune Infiltration and Improved Clinical Outcomes of PD-L1 Blockade Across PD-L1 Expression Levels.
PubMed Identifier: 35708671
author list: Ricciuti B, Wang X, Alessi JV, Rizvi H, Mahadevan NR, Li YY, Polio A, Lindsay J, Umeton R, Sinha R, Vokes NI, Recondo G, Lamberti G, Lawrence M, Vaz VR, Leonardi GC, Plodkowski AJ, Gupta H, Cherniack AD, Tolstorukov MY, Sharma B, Felt KD, Gainor JF, Ravi A, Getz G, Schalper KA, Henick B, Forde P, Anagnostou V, Jänne PA, Van Allen EM, Nishino M, Sholl LM, Christiani DC, Lin X, Rodig SJ, Hellmann MD, Awad MM
published in: JAMA oncology
information resource reference: Association of High Tumor Mutation Burden in Non-Small Cell Lung Cancers With Increased Immune Infiltration and Improved Clinical Outcomes of PD-L1 Blockade Across PD-L1 Expression Levels. JAMA Oncol. 2022 08 01; 8(8):1160-1168.
journal title abbreviation: JAMA Oncol
publication date: 2022-08-01T00:00:00
year: 2022
type: Academic Article
type: Article
type: Document
type: Information Resource

Molecular profiling identifies targeted therapy opportunities in pediatric solid cancer.
PubMed Identifier: 35739269
author list: Church AJ, Corson LB, Kao PC, Imamovic-Tuco A, Reidy D, Doan D, Kang W, Pinto N, Maese L, Laetsch TW, Kim A, Colace SI, Macy ME, Applebaum MA, Bagatell R, Sabnis AJ, Weiser DA, Glade-Bender JL, Homans AC, Hipps J, Harris H, Manning D, Al-Ibraheemi A, Li Y, Gupta H, Cherniack AD, Lo YC, Strand GR, Lee LA, Pinches RS, Lazo De La Vega L, Harden MV, Lennon NJ, Choi S, Comeau H, Harris MH, Forrest SJ, Clinton CM, Crompton BD, Kamihara J, MacConaill LE, Volchenboum SL, Lindeman NI, Van Allen E, DuBois SG, London WB, Janeway KA
published in: Nature medicine
information resource reference: Molecular profiling identifies targeted therapy opportunities in pediatric solid cancer. Nat Med. 2022 08; 28(8):1581-1589.
journal title abbreviation: Nat Med
publication date: 2022-06-23T00:00:00
year: 2022
type: Academic Article
type: Article
type: Document
type: Information Resource

A Process Framework for Ethically Deploying Artificial Intelligence in Oncology.
PubMed Identifier: 35849792
author list: Hantel A, Clancy DD, Kehl KL, Marron JM, Van Allen EM, Abel GA
published in: Journal of clinical oncology : official journal of the American Society of Clinical Oncology
information resource reference: A Process Framework for Ethically Deploying Artificial Intelligence in Oncology. J Clin Oncol. 2022 12 01; 40(34):3907-3911.
journal title abbreviation: J Clin Oncol
publication date: 2022-07-18T00:00:00
year: 2022
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1465408
type: Authorship
author rank in publication: 20
linked author: Van Allen, Eliezer
linked information resource: Tissue-resident memory and circulating T cells are early responders to pre-surgical cancer immunotherapy.

Authorship 1466159
type: Authorship
author rank in publication: 5
linked author: Van Allen, Eliezer
linked information resource: A Process Framework for Ethically Deploying Artificial Intelligence in Oncology.

Authorship 1468536
type: Authorship
author rank in publication: 18
linked author: Van Allen, Eliezer
linked information resource: Multidimensional Molecular Profiling of Metastatic Triple-Negative Breast Cancer and Immune Checkpoint Inhibitor Benefit.

Authorship 1466898
type: Authorship
author rank in publication: 44
linked author: Van Allen, Eliezer
linked information resource: Molecular profiling identifies targeted therapy opportunities in pediatric solid cancer.

Authorship 1467155
type: Authorship
author rank in publication: 31
linked author: Van Allen, Eliezer
linked information resource: Association of High Tumor Mutation Burden in Non-Small Cell Lung Cancers With Increased Immune Infiltration and Improved Clinical Outcomes of PD-L1 Blockade Across PD-L1 Expression Levels.

Tissue-resident memory and circulating T cells are early responders to pre-surgical cancer immunotherapy.
PubMed Identifier: 35803260
author list: Luoma AM, Suo S, Wang Y, Gunasti L, Porter CBM, Nabilsi N, Tadros J, Ferretti AP, Liao S, Gurer C, Chen YH, Criscitiello S, Ricker CA, Dionne D, Rozenblatt-Rosen O, Uppaluri R, Haddad RI, Ashenberg O, Regev A, Van Allen EM, MacBeath G, Schoenfeld JD, Wucherpfennig KW
published in: Cell
information resource reference: Tissue-resident memory and circulating T cells are early responders to pre-surgical cancer immunotherapy. Cell. 2022 08 04; 185(16):2918-2935.e29.
journal title abbreviation: Cell
publication date: 2022-07-07T00:00:00
year: 2022
type: Academic Article
type: Article
type: Document
type: Information Resource

Multidimensional Molecular Profiling of Metastatic Triple-Negative Breast Cancer and Immune Checkpoint Inhibitor Benefit.
PubMed Identifier: 35797509
author list: Barroso-Sousa R, Forman J, Collier K, Weber ZT, Jammihal TR, Kao KZ, Richardson ET, Keenan T, Cohen O, Manos MP, Brennick RC, Ott PA, Hodi FS, Dillon DA, Attaya V, O'Meara T, Lin NU, Van Allen EM, Rodig S, Winer EP, Mittendorf EA, Wu CJ, Wagle N, Stover DG, Shukla SA, Tolaney SM
published in: JCO precision oncology
information resource reference: Multidimensional Molecular Profiling of Metastatic Triple-Negative Breast Cancer and Immune Checkpoint Inhibitor Benefit. JCO Precis Oncol. 2022 07; 6:e2100413.
journal title abbreviation: JCO Precis Oncol
publication date: 2022-07-01T00:00:00
year: 2022
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1500123
type: Authorship
author rank in publication: 14
linked author: Van Allen, Eliezer
linked information resource: Phase Ib study of pembrolizumab in combination with trastuzumab emtansine for metastatic HER2-positive breast cancer.

Authorship 1477058
type: Authorship
author rank in publication: 3
linked author: Van Allen, Eliezer
linked information resource: https://connects.catalyst.harvard.edu/Profiles/profile/203408875

Authorship 1482589
type: Authorship
author rank in publication: 15
linked author: Van Allen, Eliezer
linked information resource: Addition of Germline Testing to Tumor-Only Sequencing Improves Detection of Pathogenic Germline Variants in Men With Advanced Prostate Cancer.

Authorship 1476823
type: Authorship
author rank in publication: 11
linked author: Van Allen, Eliezer
linked information resource: Patterns of structural variation define prostate cancer across disease states.

Authorship 1488179
type: Authorship
author rank in publication: 21
linked author: Van Allen, Eliezer
linked information resource: Mutational Footprint of Platinum Chemotherapy in a Secondary Thyroid Cancer.

Authorship 1489923
type: Authorship
author rank in publication: 14
linked author: Van Allen, Eliezer
linked information resource: Randomized Trial of Olaparib With or Without Cediranib for Metastatic Castration-Resistant Prostate Cancer: The Results From National Cancer Institute 9984.

Authorship 1501151
type: Authorship
author rank in publication: 32
linked author: Van Allen, Eliezer
linked information resource: A patient-driven clinicogenomic partnership for metastatic prostate cancer.

Patterns of structural variation define prostate cancer across disease states.
PubMed Identifier: 35943799
author list: Zhou M, Ko M, Hoge AC, Luu K, Liu Y, Russell ML, Hannon WW, Zhang Z, Carrot-Zhang J, Beroukhim R, Van Allen EM, Choudhury AD, Nelson PS, Freedman ML, Taplin ME, Meyerson M, Viswanathan SR, Ha G
published in: JCI insight
information resource reference: Patterns of structural variation define prostate cancer across disease states. JCI Insight. 2022 09 08; 7(17).
journal title abbreviation: JCI Insight
publication date: 2022-09-08T00:00:00
year: 2022
type: Academic Article
type: Article
type: Document
type: Information Resource

Randomized Trial of Olaparib With or Without Cediranib for Metastatic Castration-Resistant Prostate Cancer: The Results From National Cancer Institute 9984.
PubMed Identifier: 36256912
author list: Kim JW, McKay RR, Radke MR, Zhao S, Taplin ME, Davis NB, Monk P, Appleman LJ, Lara PN, Vaishampayan UN, Zhang J, Paul AK, Bubley G, Van Allen EM, Unlu S, Huang Y, Loda M, Shapiro GI, Glazer PM, LoRusso PM, Ivy SP, Shyr Y, Swisher EM, Petrylak DP
published in: Journal of clinical oncology : official journal of the American Society of Clinical Oncology
information resource reference: Randomized Trial of Olaparib With or Without Cediranib for Metastatic Castration-Resistant Prostate Cancer: The Results From National Cancer Institute 9984. J Clin Oncol. 2023 02 01; 41(4):871-880.
journal title abbreviation: J Clin Oncol
publication date: 2022-10-18T00:00:00
year: 2022
type: Academic Article
type: Article
type: Document
type: Information Resource

Phase Ib study of pembrolizumab in combination with trastuzumab emtansine for metastatic HER2-positive breast cancer.
PubMed Identifier: 36252998
author list: Waks AG, Keenan TE, Li T, Tayob N, Wulf GM, Richardson ET, Attaya V, Anderson L, Mittendorf EA, Overmoyer B, Winer EP, Krop IE, Agudo J, Van Allen EM, Tolaney SM
published in: Journal for immunotherapy of cancer
information resource reference: Phase Ib study of pembrolizumab in combination with trastuzumab emtansine for metastatic HER2-positive breast cancer. J Immunother Cancer. 2022 10; 10(10).
journal title abbreviation: J Immunother Cancer
publication date: 2022-10-01T00:00:00
year: 2022
type: Academic Article
type: Article
type: Document
type: Information Resource

https://connects.catalyst.harvard.edu/Profiles/profile/203408875
PubMed Identifier: 35945087
author list: Carvalho FLF, Mossanen M, Van Allen EM, Mouw KW
published in: European urology
information resource reference: Reply to Yuxuan Song, Yiqing Du, and Tao Xu's Letter to the Editor re: Matthew Mossanen, Filipe L.F. Carvalho, Vinayak Muralidhar, et al. Genomic Features of Muscle-invasive Bladder Cancer Arising After Prostate Radiotherapy. Eur Urol 2022;81:466-73. Eur Urol. 2022 11; 82(5):e141-e142.
journal title abbreviation: Eur Urol
publication date: 2022-08-06T00:00:00
year: 2022
type: Academic Article
type: Article
type: Document
type: Information Resource
label: Reply to Yuxuan Song, Yiqing Du, and Tao Xu's Letter to the Editor re: Matthew Mossanen, Filipe L.F. Carvalho, Vinayak Muralidhar, et al. Genomic Features of Muscle-invasive Bladder Cancer Arising After Prostate Radiotherapy. Eur Urol 2022;81:466-73.

Mutational Footprint of Platinum Chemotherapy in a Secondary Thyroid Cancer.
PubMed Identifier: 36075011
author list: Schiantarelli J, Pappa T, Conway J, Crowdis J, Reardon B, Dietlein F, Huang J, Stanizzi D, Carey E, Bosma-Moody A, Imamovic A, Han S, Camp S, Kofman E, Shannon E, Barletta JA, He MX, Liu D, Park J, Lorch JH, Van Allen EM
published in: JCO precision oncology
information resource reference: Mutational Footprint of Platinum Chemotherapy in a Secondary Thyroid Cancer. JCO Precis Oncol. 2022 08; 6:e2200183.
journal title abbreviation: JCO Precis Oncol
publication date: 2022-08-01T00:00:00
year: 2022
type: Academic Article
type: Article
type: Document
type: Information Resource

Addition of Germline Testing to Tumor-Only Sequencing Improves Detection of Pathogenic Germline Variants in Men With Advanced Prostate Cancer.
PubMed Identifier: 36103646
author list: Berchuck JE, Boiarsky D, Silver R, Sunkara R, McClure HM, Tsai HK, Siegmund S, Tewari AK, Nowak JA, Lindeman NI, Rana HQ, Choudhury AD, Pomerantz MM, Freedman ML, Van Allen EM, Taplin ME
published in: JCO precision oncology
information resource reference: Addition of Germline Testing to Tumor-Only Sequencing Improves Detection of Pathogenic Germline Variants in Men With Advanced Prostate Cancer. JCO Precis Oncol. 2022 Aug; 6:e2200329.
journal title abbreviation: JCO Precis Oncol
publication date: 2022-08-01T00:00:00
year: 2022
type: Academic Article
type: Article
type: Document
type: Information Resource

A patient-driven clinicogenomic partnership for metastatic prostate cancer.
PubMed Identifier: 36177448
author list: Crowdis J, Balch S, Sterlin L, Thomas BS, Camp SY, Dunphy M, Anastasio E, Shah S, Damon AL, Ramos R, Sosa DM, Small IK, Tomson BN, Nguyen CM, McGillicuddy M, Chastain PS, He MX, Cheung ATM, Wankowicz S, Tewari AK, Kim D, AlDubayan SH, Dowdye A, Zola B, Nowak J, Manarite J, Gunn IH, Olson B, Lander ES, Painter CA, Wagle N, Van Allen EM
published in: Cell genomics
information resource reference: A patient-driven clinicogenomic partnership for metastatic prostate cancer. Cell Genom. 2022 Sep 14; 2(9).
journal title abbreviation: Cell Genom
publication date: 2022-08-19T00:00:00
year: 2022
type: Academic Article
type: Article
type: Document
type: Information Resource

Disparities in the Inclusion of Racial and Ethnic Minority Groups and Older Adults in Prostate Cancer Clinical Trials: A Meta-analysis.
PubMed Identifier: 36416812
author list: Riaz IB, Islam M, Ikram W, Naqvi SAA, Maqsood H, Saleem Y, Riaz A, Ravi P, Wang Z, Hussain SA, Warner JL, Odedina FT, Duma N, Singh P, Kehl KL, Kamran SC, Murad MH, Landman A, Van Allen E, Bryce AH
published in: JAMA oncology
information resource reference: Disparities in the Inclusion of Racial and Ethnic Minority Groups and Older Adults in Prostate Cancer Clinical Trials: A Meta-analysis. JAMA Oncol. 2023 02 01; 9(2):180-187.
journal title abbreviation: JAMA Oncol
publication date: 2023-02-01T00:00:00
year: 2023
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1505459
type: Authorship
author rank in publication: 19
linked author: Van Allen, Eliezer
linked information resource: Disparities in the Inclusion of Racial and Ethnic Minority Groups and Older Adults in Prostate Cancer Clinical Trials: A Meta-analysis.

Germline variants associated with toxicity to immune checkpoint blockade.
PubMed Identifier: 36526723
author list: Groha S, Alaiwi SA, Xu W, Naranbhai V, Nassar AH, Bakouny Z, El Zarif T, Saliby RM, Wan G, Rajeh A, Adib E, Nuzzo PV, Schmidt AL, Labaki C, Ricciuti B, Alessi JV, Braun DA, Shukla SA, Keenan TE, Van Allen E, Awad MM, Manos M, Rahma O, Zubiri L, Villani AC, Fairfax B, Hammer C, Khan Z, Reynolds K, Semenov Y, Schrag D, Kehl KL, Freedman ML, Choueiri TK, Gusev A
published in: Nature medicine
information resource reference: Germline variants associated with toxicity to immune checkpoint blockade. Nat Med. 2022 12; 28(12):2584-2591.
journal title abbreviation: Nat Med
publication date: 2022-12-16T00:00:00
year: 2022
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1514372
type: Authorship
author rank in publication: 20
linked author: Van Allen, Eliezer
linked information resource: Germline variants associated with toxicity to immune checkpoint blockade.

Racial and ethnic disparities in a real-world precision oncology data registry.
PubMed Identifier: 36658153
author list: Cheung ATM, Palapattu EL, Pompa IR, Aldrighetti CM, Niemierko A, Willers H, Huang F, Vapiwala N, Van Allen E, Kamran SC
published in: NPJ precision oncology
information resource reference: Racial and ethnic disparities in a real-world precision oncology data registry. NPJ Precis Oncol. 2023 Jan 19; 7(1):7.
journal title abbreviation: NPJ Precis Oncol
publication date: 2023-01-19T00:00:00
year: 2023
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1517621
type: Authorship
author rank in publication: 9
linked author: Van Allen, Eliezer
linked information resource: Racial and ethnic disparities in a real-world precision oncology data registry.

Authorship 1521340
type: Authorship
author rank in publication: 18
linked author: Van Allen, Eliezer
linked information resource: Spatially aware deep learning reveals tumor heterogeneity patterns that encode distinct kidney cancer states.

Authorship 1521351
type: Authorship
author rank in publication: 16
linked author: Van Allen, Eliezer
linked information resource: Integrative Analysis of Germline Rare Variants in Clear and Non-Clear Cell Renal Cell Carcinoma.

Spatially aware deep learning reveals tumor heterogeneity patterns that encode distinct kidney cancer states.
PubMed Identifier: 36712053
author list: Nyman J, Denize T, Bakouny Z, Labaki C, Titchen BM, Bi K, Hari SN, Rosenthal J, Mehta N, Jiang B, Sharma B, Felt K, Umeton R, Braun DA, Rodig S, Choueiri TK, Signoretti S, Van Allen EM
published in: bioRxiv : the preprint server for biology
information resource reference: Spatially aware deep learning reveals tumor heterogeneity patterns that encode distinct kidney cancer states. bioRxiv. 2023 Feb 20.
journal title abbreviation: bioRxiv
publication date: 2023-02-20T00:00:00
year: 2023
type: Academic Article
type: Article
type: Document
type: Information Resource

Integrative Analysis of Germline Rare Variants in Clear and Non-Clear Cell Renal Cell Carcinoma.
PubMed Identifier: 36712083
author list: Han S, Camp SY, Chu H, Collins R, Gillani R, Park J, Bakouny Z, Ricker CA, Reardon B, Moore N, Kofman E, Labaki C, Braun D, Choueiri TK, AlDubayan SH, Van Allen EM
published in: medRxiv : the preprint server for health sciences
information resource reference: Integrative Analysis of Germline Rare Variants in Clear and Non-Clear Cell Renal Cell Carcinoma. medRxiv. 2023 Jan 19.
journal title abbreviation: medRxiv
publication date: 2023-01-19T00:00:00
year: 2023
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1523767
type: Authorship
author rank in publication: 14
linked author: Van Allen, Eliezer
linked information resource: A Phase I Study of Combination Olaparib and Radium-223 in Men with Metastatic Castration-Resistant Prostate Cancer (mCRPC) with Bone Metastases (COMRADE).

A Phase I Study of Combination Olaparib and Radium-223 in Men with Metastatic Castration-Resistant Prostate Cancer (mCRPC) with Bone Metastases (COMRADE).
PubMed Identifier: 36780008
author list: Pan E, Xie W, Ajmera A, Araneta A, Jamieson C, Folefac E, Hussain A, Kyriakopoulos CE, Olson A, Parikh M, Parikh R, Saraiya B, Ivy SP, Van Allen EM, Lindeman NI, Kochupurakkal BS, Shapiro GI, McKay RR
published in: Molecular cancer therapeutics
information resource reference: A Phase I Study of Combination Olaparib and Radium-223 in Men with Metastatic Castration-Resistant Prostate Cancer (mCRPC) with Bone Metastases (COMRADE). Mol Cancer Ther. 2023 04 03; 22(4):511-518.
journal title abbreviation: Mol Cancer Ther
publication date: 2023-04-03T00:00:00
year: 2023
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1528326
type: Authorship
author rank in publication: 14
linked author: Van Allen, Eliezer
linked information resource: First-line Systemic Treatment Options for Metastatic Castration-Sensitive Prostate Cancer: A Living Systematic Review and Network Meta-analysis.

Authorship 1528307
type: Authorship
author rank in publication: 42
linked author: Van Allen, Eliezer
linked information resource: Overcoming Barriers to Tumor Genomic Profiling through Direct-to-Patient Outreach.

Overcoming Barriers to Tumor Genomic Profiling through Direct-to-Patient Outreach.
PubMed Identifier: 36862133
author list: Doe-Tetteh SA, Camp SY, Reales D, Crowdis J, Noronha AM, Wolff B, Alano T, Galle J, Selcuklu SD, Viale A, Socci ND, Liu YL, Tew WP, Aghajanian C, Ladanyi M, He MX, AlDubayan SH, Mazor RD, Shpilberg O, Hershkovitz-Rokah O, Riancho JA, Hernandez JL, Gonzalez-Vela MC, Buthorn JJ, Wilson M, Webber AE, Yabe M, Petrova-Drus K, Rosenblum M, Durham BH, Abdel-Wahab O, Berger MF, Donoghue MTA, Kung AL, Glade Bender J, Shukla NN, Funt SA, Dogan A, Soslow RA, Al-Ahmadie H, Feldman DR, Van Allen EM, Diamond EL, Solit DB
published in: Clinical cancer research : an official journal of the American Association for Cancer Research
information resource reference: Overcoming Barriers to Tumor Genomic Profiling through Direct-to-Patient Outreach. Clin Cancer Res. 2023 07 05; 29(13):2445-2455.
journal title abbreviation: Clin Cancer Res
publication date: 2023-07-05T00:00:00
year: 2023
type: Academic Article
type: Article
type: Document
type: Information Resource

First-line Systemic Treatment Options for Metastatic Castration-Sensitive Prostate Cancer: A Living Systematic Review and Network Meta-analysis.
PubMed Identifier: 36862387
author list: Riaz IB, Naqvi SAA, He H, Asghar N, Siddiqi R, Liu H, Singh P, Childs DS, Ravi P, Hussain SA, Murad MH, Boorjian SA, Sweeney C, Van Allen EM, Bryce AH
published in: JAMA oncology
information resource reference: First-line Systemic Treatment Options for Metastatic Castration-Sensitive Prostate Cancer: A Living Systematic Review and Network Meta-analysis. JAMA Oncol. 2023 05 01; 9(5):635-645.
journal title abbreviation: JAMA Oncol
publication date: 2023-05-01T00:00:00
year: 2023
type: Academic Article
type: Article
type: Document
type: Information Resource

Impact of an Expanded Definition of Family History on Outcomes of Active Surveillance for Prostate Cancer.
PubMed Identifier: 36951811
author list: Schneider AC, Chandrasekar T, Bowler N, Fogg R, Leong JY, Gusev A, Rodgers LH, McCormick SR, Dahl DM, Efstathiou JA, Blute ML, Zietman AL, Wu CL, Smith MR, Van Allen EM, Feldman AS, Salari K
published in: The Journal of urology
information resource reference: Impact of an Expanded Definition of Family History on Outcomes of Active Surveillance for Prostate Cancer. J Urol. 2023 06; 209(6):1112-1119.
journal title abbreviation: J Urol
publication date: 2023-03-09T00:00:00
year: 2023
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1533311
type: Authorship
author rank in publication: 15
linked author: Van Allen, Eliezer
linked information resource: Impact of an Expanded Definition of Family History on Outcomes of Active Surveillance for Prostate Cancer.

Molecular markers of metastatic disease in KRAS-mutant lung adenocarcinoma.
PubMed Identifier: 37121400
author list: Boiarsky D, Lydon CA, Chambers ES, Sholl LM, Nishino M, Skoulidis F, Heymach JV, Luo J, Awad MM, Janne PA, Van Allen EM, Barbie DA, Vokes NI
published in: Annals of oncology : official journal of the European Society for Medical Oncology
information resource reference: Molecular markers of metastatic disease in KRAS-mutant lung adenocarcinoma. Ann Oncol. 2023 07; 34(7):589-604.
journal title abbreviation: Ann Oncol
publication date: 2023-04-29T00:00:00
year: 2023
type: Academic Article
type: Article
type: Document
type: Information Resource

Circulating and Intratumoral Immune Determinants of Response to Atezolizumab plus Bevacizumab in Patients with Variant Histology or Sarcomatoid Renal Cell Carcinoma.
PubMed Identifier: 37279009
author list: Saliby RM, El Zarif T, Bakouny Z, Shah V, Xie W, Flippot R, Denize T, Kane MH, Madsen KN, Ficial M, Hirsch L, Wei XX, Steinharter JA, Harshman LC, Vaishampayan UN, Severgnini M, McDermott DF, Lee GM, Xu W, Van Allen EM, McGregor BA, Signoretti S, Choueiri TK, McKay RR, Braun DA
published in: Cancer immunology research
information resource reference: Circulating and Intratumoral Immune Determinants of Response to Atezolizumab plus Bevacizumab in Patients with Variant Histology or Sarcomatoid Renal Cell Carcinoma. Cancer Immunol Res. 2023 08 03; 11(8):1114-1124.
journal title abbreviation: Cancer Immunol Res
publication date: 2023-08-03T00:00:00
year: 2023
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1567676
type: Authorship
author rank in publication: 11
linked author: Van Allen, Eliezer
linked information resource: Molecular markers of metastatic disease in KRAS-mutant lung adenocarcinoma.

Authorship 1569667
type: Authorship
author rank in publication: 20
linked author: Van Allen, Eliezer
linked information resource: Circulating and Intratumoral Immune Determinants of Response to Atezolizumab plus Bevacizumab in Patients with Variant Histology or Sarcomatoid Renal Cell Carcinoma.

Authorship 1565692
type: Authorship
author rank in publication: 28
linked author: Van Allen, Eliezer
linked information resource: Interferon signaling promotes tolerance to chromosomal instability during metastatic evolution in renal cancer.

Authorship 1566880
type: Authorship
author rank in publication: 10
linked author: Van Allen, Eliezer
linked information resource: Current Landscape of Genomic Biomarkers in Clear Cell Renal Cell Carcinoma.

Interferon signaling promotes tolerance to chromosomal instability during metastatic evolution in renal cancer.
PubMed Identifier: 37365326
author list: Perelli L, Carbone F, Zhang L, Huang JK, Le C, Khan H, Citron F, Del Poggetto E, Gutschner T, Tomihara H, Soeung M, Minelli R, Srinivasan S, Peoples M, Lam TNA, Lundgren S, Xia R, Zhu C, Mohamed AMT, Zhang J, Sircar K, Sgambato A, Gao J, Jonasch E, Draetta GF, Futreal A, Bakouny Z, Van Allen EM, Choueiri T, Signoretti S, Msaouel P, Litchfield K, Turajlic S, Wang L, Chen YB, Di Natale RG, Hakimi AA, Giuliani V, Heffernan TP, Viale A, Bristow CA, Tannir NM, Carugo A, Genovese G
published in: Nature cancer
information resource reference: Interferon signaling promotes tolerance to chromosomal instability during metastatic evolution in renal cancer. Nat Cancer. 2023 07; 4(7):984-1000.
journal title abbreviation: Nat Cancer
publication date: 2023-06-26T00:00:00
year: 2023
type: Academic Article
type: Article
type: Document
type: Information Resource

Current Landscape of Genomic Biomarkers in Clear Cell Renal Cell Carcinoma.
PubMed Identifier: 37085424
author list: Cotta BH, Choueiri TK, Cieslik M, Ghatalia P, Mehra R, Morgan TM, Palapattu GS, Shuch B, Vaishampayan U, Van Allen E, Ari Hakimi A, Salami SS
published in: European urology
information resource reference: Current Landscape of Genomic Biomarkers in Clear Cell Renal Cell Carcinoma. Eur Urol. 2023 08; 84(2):166-175.
journal title abbreviation: Eur Urol
publication date: 2023-04-19T00:00:00
year: 2023
type: Academic Article
type: Article
type: Document
type: Information Resource

Genome-guided discovery of cancer therapeutic targets.
PubMed Identifier: 37572322
author list: Konda P, Garinet S, Van Allen EM, Viswanathan SR
published in: Cell reports
information resource reference: Genome-guided discovery of cancer therapeutic targets. Cell Rep. 2023 Aug 29; 42(8):112978.
journal title abbreviation: Cell Rep
publication date: 2023-08-10T00:00:00
year: 2023
type: Academic Article
type: Article
type: Document
type: Information Resource

Integration of Genomic Sequencing Drives Therapeutic Targeting of PDGFRA in T-Cell Acute Lymphoblastic Leukemia/Lymphoblastic Lymphoma.
PubMed Identifier: 37725576
author list: Paolino J, Dimitrov B, Apsel Winger B, Sandoval-Perez A, Rangarajan AV, Ocasio-Martinez N, Tsai HK, Li Y, Robichaud AL, Khalid D, Hatton C, Gillani R, Polonen P, Dilig A, Gotti G, Kavanagh J, Adhav AA, Gow S, Tsai J, Li Y, Ebert BL, Van Allen EM, Bledsoe J, Kim AS, Tasian SK, Cooper SL, Cooper TM, Hijiya N, Sulis ML, Shukla NN, Magee JA, Mullighan CG, Burke MJ, Luskin MR, Mar BG, Jacobson MP, Harris MH, Stegmaier K, Place AE, Pikman Y
published in: Clinical cancer research : an official journal of the American Association for Cancer Research
information resource reference: Integration of Genomic Sequencing Drives Therapeutic Targeting of PDGFRA in T-Cell Acute Lymphoblastic Leukemia/Lymphoblastic Lymphoma. Clin Cancer Res. 2023 11 14; 29(22):4613-4626.
journal title abbreviation: Clin Cancer Res
publication date: 2023-11-14T00:00:00
year: 2023
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1590810
type: Authorship
author rank in publication: 3
linked author: Van Allen, Eliezer
linked information resource: Reply to: Addressing racial and ethnic disparities in AACR project GENIE.

Authorship 1588905
type: Authorship
author rank in publication: 22
linked author: Van Allen, Eliezer
linked information resource: Integration of Genomic Sequencing Drives Therapeutic Targeting of PDGFRA in T-Cell Acute Lymphoblastic Leukemia/Lymphoblastic Lymphoma.

Authorship 1591003
type: Authorship
author rank in publication: 12
linked author: Van Allen, Eliezer
linked information resource: Interplay of Mendelian and polygenic risk factors in Arab breast cancer patients.

Authorship 1589147
type: Authorship
author rank in publication: 18
linked author: Van Allen, Eliezer
linked information resource: Spatially aware deep learning reveals tumor heterogeneity patterns that encode distinct kidney cancer states.

Authorship 1583407
type: Authorship
author rank in publication: 34
linked author: Van Allen, Eliezer
linked information resource: Intertumoral lineage diversity and immunosuppressive transcriptional programs in well-differentiated gastroenteropancreatic neuroendocrine tumors.

Authorship 1590996
type: Authorship
author rank in publication: 6
linked author: Van Allen, Eliezer
linked information resource: Empirical evaluation of language modeling to ascertain cancer outcomes from clinical text reports.

Authorship 1584539
type: Authorship
author rank in publication: 3
linked author: Van Allen, Eliezer
linked information resource: Genome-guided discovery of cancer therapeutic targets.

Reply to: Addressing racial and ethnic disparities in AACR project GENIE.
PubMed Identifier: 37653109
author list: Cheung ATM, Niemierko A, Van Allen E, Vapiwala N, Kamran SC
published in: NPJ precision oncology
information resource reference: Reply to: Addressing racial and ethnic disparities in AACR project GENIE. NPJ Precis Oncol. 2023 Aug 31; 7(1):82.
journal title abbreviation: NPJ Precis Oncol
publication date: 2023-08-31T00:00:00
year: 2023
type: Academic Article
type: Article
type: Document
type: Information Resource

Spatially aware deep learning reveals tumor heterogeneity patterns that encode distinct kidney cancer states.
PubMed Identifier: 37729872
author list: Nyman J, Denize T, Bakouny Z, Labaki C, Titchen BM, Bi K, Hari SN, Rosenthal J, Mehta N, Jiang B, Sharma B, Felt K, Umeton R, Braun DA, Rodig S, Choueiri TK, Signoretti S, Van Allen EM
published in: Cell reports. Medicine
information resource reference: Spatially aware deep learning reveals tumor heterogeneity patterns that encode distinct kidney cancer states. Cell Rep Med. 2023 09 19; 4(9):101189.
journal title abbreviation: Cell Rep Med
publication date: 2023-09-19T00:00:00
year: 2023
type: Academic Article
type: Article
type: Document
type: Information Resource

Empirical evaluation of language modeling to ascertain cancer outcomes from clinical text reports.
PubMed Identifier: 37658330
author list: Elmarakeby HA, Trukhanov PS, Arroyo VM, Riaz IB, Schrag D, Van Allen EM, Kehl KL
published in: BMC bioinformatics
information resource reference: Empirical evaluation of language modeling to ascertain cancer outcomes from clinical text reports. BMC Bioinformatics. 2023 Sep 02; 24(1):328.
journal title abbreviation: BMC Bioinformatics
publication date: 2023-09-02T00:00:00
year: 2023
type: Academic Article
type: Article
type: Document
type: Information Resource

Interplay of Mendelian and polygenic risk factors in Arab breast cancer patients.
PubMed Identifier: 37658461
author list: Al-Jumaan M, Chu H, Alsulaiman A, Camp SY, Han S, Gillani R, Al Marzooq Y, Almulhim F, Vatte C, Al Nemer A, Almuhanna A, Van Allen EM, Al-Ali A, AlDubayan SH
published in: Genome medicine
information resource reference: Interplay of Mendelian and polygenic risk factors in Arab breast cancer patients. Genome Med. 2023 09 01; 15(1):65.
journal title abbreviation: Genome Med
publication date: 2023-09-01T00:00:00
year: 2023
type: Academic Article
type: Article
type: Document
type: Information Resource

Intertumoral lineage diversity and immunosuppressive transcriptional programs in well-differentiated gastroenteropancreatic neuroendocrine tumors.
PubMed Identifier: 37756410
author list: Hoffman SE, Dowrey TW, Villacorta Martin C, Bi K, Titchen B, Johri S, DelloStritto L, Patel M, Mackichan C, Inga S, Chen J, Grimaldi G, Napolitano S, Wakiro I, Wu J, Yeung J, Rotem A, Sicinska E, Shannon E, Clancy T, Wang J, Denning S, Brais L, Besson NR, Pfaff KL, Huang Y, Kao KZ, Rodig S, Hornick JL, Vigneau S, Park J, Kulke MH, Chan J, Van Allen EM, Murphy GJ
published in: Science advances
information resource reference: Intertumoral lineage diversity and immunosuppressive transcriptional programs in well-differentiated gastroenteropancreatic neuroendocrine tumors. Sci Adv. 2023 09 29; 9(39):eadd9668.
journal title abbreviation: Sci Adv
publication date: 2023-09-27T00:00:00
year: 2023
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1601946
type: Authorship
author rank in publication: 13
linked author: Van Allen, Eliezer
linked information resource: Genomic Tumor Correlates of Clinical Outcomes Following Organ-Sparing Chemoradiation Therapy for Bladder Cancer.

Genomic Tumor Correlates of Clinical Outcomes Following Organ-Sparing Chemoradiation Therapy for Bladder Cancer.
PubMed Identifier: 37870965
author list: Kamran SC, Zhou Y, Otani K, Drumm M, Otani Y, Wu S, Wu CL, Feldman AS, Wszolek M, Lee RJ, Saylor PJ, Lennerz J, Van Allen E, Willers H, Hong TS, Liu Y, Davicioni E, Gibb EA, Shipley WU, Mouw KW, Efstathiou JA, Miyamoto DT
published in: Clinical cancer research : an official journal of the American Association for Cancer Research
information resource reference: Genomic Tumor Correlates of Clinical Outcomes Following Organ-Sparing Chemoradiation Therapy for Bladder Cancer. Clin Cancer Res. 2023 12 15; 29(24):5116-5127.
journal title abbreviation: Clin Cancer Res
publication date: 2023-12-15T00:00:00
year: 2023
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1609181
type: Authorship
author rank in publication: 80
linked author: Van Allen, Eliezer
linked information resource: The role of APOBEC3B in lung tumor evolution and targeted cancer therapy resistance.

The role of APOBEC3B in lung tumor evolution and targeted cancer therapy resistance.
PubMed Identifier: 38049664
author list: Caswell DR, Gui P, Mayekar MK, Law EK, Pich O, Bailey C, Boumelha J, Kerr DL, Blakely CM, Manabe T, Martinez-Ruiz C, Bakker B, De Dios Palomino Villcas J, I Vokes N, Dietzen M, Angelova M, Gini B, Tamaki W, Allegakoen P, Wu W, Humpton TJ, Hill W, Tomaschko M, Lu WT, Haderk F, Al Bakir M, Nagano A, Gimeno-Valiente F, de Carné Trécesson S, Vendramin R, Barbè V, Mugabo M, Weeden CE, Rowan A, McCoach CE, Almeida B, Green M, Gomez C, Nanjo S, Barbosa D, Moore C, Przewrocka J, Black JRM, Grönroos E, Suarez-Bonnet A, Priestnall SL, Zverev C, Lighterness S, Cormack J, Olivas V, Cech L, Andrews T, Rule B, Jiao Y, Zhang X, Ashford P, Durfee C, Venkatesan S, Temiz NA, Tan L, Larson LK, Argyris PP, Brown WL, Yu EA, Rotow JK, Guha U, Roper N, Yu J, Vogel RI, Thomas NJ, Marra A, Selenica P, Yu H, Bakhoum SF, Chew SK, Reis-Filho JS, Jamal-Hanjani M, Vousden KH, McGranahan N, Van Allen EM, Kanu N, Harris RS, Downward J, Bivona TG, Swanton C
published in: Nature genetics
information resource reference: The role of APOBEC3B in lung tumor evolution and targeted cancer therapy resistance. Nat Genet. 2024 Jan; 56(1):60-73.
journal title abbreviation: Nat Genet
publication date: 2023-12-04T00:00:00
year: 2023
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1619801
type: Authorship
author rank in publication: 3
linked author: Van Allen, Eliezer
linked information resource: Historical perspective and future directions: computational science in immuno-oncology.

Historical perspective and future directions: computational science in immuno-oncology.
PubMed Identifier: 38191244
author list: Ricker CA, Meli K, Van Allen EM
published in: Journal for immunotherapy of cancer
information resource reference: Historical perspective and future directions: computational science in immuno-oncology. J Immunother Cancer. 2024 01 08; 12(1).
journal title abbreviation: J Immunother Cancer
publication date: 2024-01-08T00:00:00
year: 2024
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1623933
type: Authorship
author rank in publication: 21
linked author: Van Allen, Eliezer
linked information resource: Biomarkers of pembrolizumab efficacy in advanced anal squamous cell carcinoma: analysis of a phase II clinical trial and a cohort of long-term responders.

Biomarkers of pembrolizumab efficacy in advanced anal squamous cell carcinoma: analysis of a phase II clinical trial and a cohort of long-term responders.
PubMed Identifier: 38272561
author list: Huffman BM, Singh H, Ali LR, Horick N, Wang SJ, Hoffman MT, Metayer KA, Murray S, Bird A, Abrams TA, Biller LH, Chan JA, Meyerhardt JA, McCleary NJ, Goessling W, Patel AK, Wisch JS, Yurgelun MB, Mouw K, Reardon B, Van Allen EM, Zerillo JA, Clark JW, Parikh A, Mayer RJ, Schlechter B, Ng K, Kumar S, Del Vecchio Fitz C, Kuperwasser C, Hanna GJ, Coveler AL, Rubinson DA, Welsh EL, Pfaff K, Rodig S, Dougan SK, Cleary JM
published in: Journal for immunotherapy of cancer
information resource reference: Biomarkers of pembrolizumab efficacy in advanced anal squamous cell carcinoma: analysis of a phase II clinical trial and a cohort of long-term responders. J Immunother Cancer. 2024 01 25; 12(1).
journal title abbreviation: J Immunother Cancer
publication date: 2024-01-25T00:00:00
year: 2024
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1639458
type: Authorship
author rank in publication: 16
linked author: Van Allen, Eliezer
linked information resource: Integrative Analysis of Germline Rare Variants in Clear and Non-clear Cell Renal Cell Carcinoma.

Authorship 1638956
type: Authorship
author rank in publication: 14
linked author: Van Allen, Eliezer
linked information resource: Randomized Phase II Study Evaluating the Addition of Pembrolizumab to Radium-223 in Metastatic Castration-resistant Prostate Cancer.

Authorship 1638736
type: Authorship
author rank in publication: 6
linked author: Van Allen, Eliezer
linked information resource: Perspectives of Oncologists on the Ethical Implications of Using Artificial Intelligence for Cancer Care.

Integrative Analysis of Germline Rare Variants in Clear and Non-clear Cell Renal Cell Carcinoma.
PubMed Identifier: 38496821
author list: Han SH, Camp SY, Chu H, Collins R, Gillani R, Park J, Bakouny Z, Ricker CA, Reardon B, Moore N, Kofman E, Labaki C, Braun D, Choueiri TK, AlDubayan SH, Van Allen EM
published in: European urology open science
information resource reference: Integrative Analysis of Germline Rare Variants in Clear and Non-clear Cell Renal Cell Carcinoma. Eur Urol Open Sci. 2024 Apr; 62:107-122.
journal title abbreviation: Eur Urol Open Sci
publication date: 2024-03-08T00:00:00
year: 2024
type: Academic Article
type: Article
type: Document
type: Information Resource

Perspectives of Oncologists on the Ethical Implications of Using Artificial Intelligence for Cancer Care.
PubMed Identifier: 38546644
author list: Hantel A, Walsh TP, Marron JM, Kehl KL, Sharp R, Van Allen E, Abel GA
published in: JAMA network open
information resource reference: Perspectives of Oncologists on the Ethical Implications of Using Artificial Intelligence for Cancer Care. JAMA Netw Open. 2024 03 04; 7(3):e244077.
journal title abbreviation: JAMA Netw Open
publication date: 2024-03-04T00:00:00
year: 2024
type: Academic Article
type: Article
type: Document
type: Information Resource

Randomized Phase II Study Evaluating the Addition of Pembrolizumab to Radium-223 in Metastatic Castration-resistant Prostate Cancer.
PubMed Identifier: 38552171
author list: Choudhury AD, Kwak L, Cheung A, Allaire KM, Marquez J, Yang DD, Tripathi A, Kilar JM, Flynn M, Maynard B, Reichel R, Pace AF, Chen BK, Van Allen EM, Kilbridge K, Wei XX, McGregor BA, Pomerantz MM, Bhatt RS, Sweeney CJ, Bubley GJ, Jacene HA, Taplin ME, Huang FW, Harshman LC, Fong L
published in: Cancer immunology research
information resource reference: Randomized Phase II Study Evaluating the Addition of Pembrolizumab to Radium-223 in Metastatic Castration-resistant Prostate Cancer. Cancer Immunol Res. 2024 Jun 04; 12(6):704-718.
journal title abbreviation: Cancer Immunol Res
publication date: 2024-06-04T00:00:00
year: 2024
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1643053
type: Authorship
author rank in publication: 12
linked author: Van Allen, Eliezer
linked information resource: PCO24-175: Immune Cell Dynamics After Radiotherapy for Oligometastatic Prostate Cancer.

Authorship 1643022
type: Authorship
author rank in publication: 21
linked author: Van Allen, Eliezer
linked information resource: Impact of renal cell carcinoma molecular subtypes on immunotherapy and targeted therapy outcomes.

Authorship 1641261
type: Authorship
author rank in publication: 5
linked author: Van Allen, Eliezer
linked information resource: Artificial Intelligence in Oncology: Current Landscape, Challenges, and Future Directions.

PCO24-175: Immune Cell Dynamics After Radiotherapy for Oligometastatic Prostate Cancer.
PubMed Identifier: 38579846
author list: Kamran SC, Otani Y, Qi D, Pompa IR, Dzeng RK, Pittie R, Chung E, Otani K, Wo JY, Zietman AL, Reeves PM, Van Allen EM, Efstathiou JA, Miyamoto DT
published in: Journal of the National Comprehensive Cancer Network : JNCCN
information resource reference: PCO24-175: Immune Cell Dynamics After Radiotherapy for Oligometastatic Prostate Cancer. J Natl Compr Canc Netw. 2024 Apr 05; 22(2.5).
journal title abbreviation: J Natl Compr Canc Netw
publication date: 2024-04-05T00:00:00
year: 2024
type: Academic Article
type: Article
type: Document
type: Information Resource

Artificial Intelligence in Oncology: Current Landscape, Challenges, and Future Directions.
PubMed Identifier: 38597966
author list: Lotter W, Hassett MJ, Schultz N, Kehl KL, Van Allen EM, Cerami E
published in: Cancer discovery
information resource reference: Artificial Intelligence in Oncology: Current Landscape, Challenges, and Future Directions. Cancer Discov. 2024 May 01; 14(5):711-726.
journal title abbreviation: Cancer Discov
publication date: 2024-05-01T00:00:00
year: 2024
type: Academic Article
type: Article
type: Document
type: Information Resource

Impact of renal cell carcinoma molecular subtypes on immunotherapy and targeted therapy outcomes.
PubMed Identifier: 38579722
author list: Saliby RM, Labaki C, Jammihal TR, Xie W, Sun M, Shah V, Saad E, Kane MH, Kashima S, Sadak K, El Zarif T, Poduval D, Motzer RJ, Powles T, Rini BI, Albiges L, Pal SK, McGregor BA, McKay RR, Signoretti S, Van Allen EM, Shukla SA, Choueiri TK, Braun DA
published in: Cancer cell
information resource reference: Impact of renal cell carcinoma molecular subtypes on immunotherapy and targeted therapy outcomes. Cancer Cell. 2024 May 13; 42(5):732-735.
journal title abbreviation: Cancer Cell
publication date: 2024-04-04T00:00:00
year: 2024
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 618638
type: Authorship
linked author: Van Allen, Eliezer
linked information resource: A Common Language for Transformative Healthcare Networking

Dissecting Integrated Cellular Programs Promoting Platinum Resistance and Progression in Bladder Cancer
end date: 2029-03-31
principal investigator name: VAN ALLEN, ELIEZER M
start date: 2024-04-01
type: Grant
sponsor award id: R01CA279221

Dissecting Convergent Somatic and Germline Alterations that Mediate the Origins and Evolution of Kidney Cancer
end date: 2028-12-31
principal investigator name: VAN ALLEN, ELIEZER M
start date: 2024-01-01
type: Grant
sponsor award id: R01CA278980

Principal Investigator
type: Researcher Role
researcher role of: Van Allen, Eliezer
contributes to: Dissecting Convergent Somatic and Germline Alterations that Mediate the Origins and Evolution of Kidney Cancer

Principal Investigator
type: Researcher Role
researcher role of: Van Allen, Eliezer
contributes to: Dissecting Integrated Cellular Programs Promoting Platinum Resistance and Progression in Bladder Cancer

Co-Principal Investigator
type: Researcher Role
researcher role of: Van Allen, Eliezer
contributes to: Count Me In: Partnering with patients to define the clinical and genomic landscape of rare aggressive sarcomas in children and adults

Co-Principal Investigator
type: Researcher Role
researcher role of: Van Allen, Eliezer
contributes to: The Cellular Geography of Therapeutic Resistance in Cancer

Authorship 1649981
type: Authorship
author rank in publication: 10
linked author: Van Allen, Eliezer
linked information resource: Somatic structural variants drive distinct modes of oncogenesis in melanoma.

Authorship 1652959
type: Authorship
author rank in publication: 18
linked author: Van Allen, Eliezer
linked information resource: Rare germline structural variants increase risk for pediatric solid tumors.

Somatic structural variants drive distinct modes of oncogenesis in melanoma.
PubMed Identifier: 38758740
author list: Conway JR, Gillani R, Crowdis J, Reardon B, Park J, Han S, Titchen B, Benamar M, Haq R, Van Allen EM
published in: The Journal of clinical investigation
information resource reference: Somatic structural variants drive distinct modes of oncogenesis in melanoma. J Clin Invest. 2024 May 14; 134(13).
journal title abbreviation: J Clin Invest
publication date: 2024-05-14T00:00:00
year: 2024
type: Academic Article
type: Article
type: Document
type: Information Resource

Rare germline structural variants increase risk for pediatric solid tumors.
PubMed Identifier: 38746320
author list: Gillani R, Collins RL, Crowdis J, Garza A, Jones JK, Walker M, Sanchis-Juan A, Whelan C, Pierce-Hoffman E, Talkowski M, Brand H, Haigis K, LoPiccolo J, AlDubayan SH, Gusev A, Crompton BD, Janeway KA, Van Allen EM
published in: bioRxiv : the preprint server for biology
information resource reference: Rare germline structural variants increase risk for pediatric solid tumors. bioRxiv. 2024 Apr 29.
journal title abbreviation: bioRxiv
publication date: 2024-04-29T00:00:00
year: 2024
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1662219
type: Authorship
author rank in publication: 32
linked author: Van Allen, Eliezer
linked information resource: Epigenomic signatures of sarcomatoid differentiation to guide the treatment of renal cell carcinoma.

Authorship 1659728
type: Authorship
author rank in publication: 2
linked author: Van Allen, Eliezer
linked information resource: AI and immunology.

Authorship 1659711
type: Authorship
author rank in publication: 15
linked author: Van Allen, Eliezer
linked information resource: Urine Biopsy as Dynamic Biomarker to Enhance Clinical Staging of Bladder Cancer in Radical Cystectomy Candidates.

Epigenomic signatures of sarcomatoid differentiation to guide the treatment of renal cell carcinoma.
PubMed Identifier: 38870013
author list: El Zarif T, Semaan K, Eid M, Seo JH, Garinet S, Davidsohn MP, Sahgal P, Fortunato B, Canniff J, Nassar AH, Abou Alaiwi S, Bakouny Z, Lakshminarayanan G, Savignano H, Lyons K, Matar S, Ali A, Saad E, Saliby RM, Cordeiro P, Zhang Z, El Ahmar N, Laimon YN, Labaki C, Shah V, Freeman D, O'Toole J, Lee GM, Hwang J, Pomerantz M, Signoretti S, Van Allen EM, Xie W, Berchuck JE, Viswanathan SR, Braun DA, Choueiri TK, Freedman ML, Baca SC
published in: Cell reports
information resource reference: Epigenomic signatures of sarcomatoid differentiation to guide the treatment of renal cell carcinoma. Cell Rep. 2024 06 25; 43(6):114350.
journal title abbreviation: Cell Rep
publication date: 2024-06-12T00:00:00
year: 2024
type: Academic Article
type: Article
type: Document
type: Information Resource

Urine Biopsy as Dynamic Biomarker to Enhance Clinical Staging of Bladder Cancer in Radical Cystectomy Candidates.
PubMed Identifier: 38865671
author list: Satyal U, Valentine H, Liu D, Slifker M, Lallas CD, Trabulsi EJ, Bukavina L, Szeto L, Hoffman-Censits JH, Mouw KW, Faltas BM, Grivas P, Ibragimova I, Porten SP, Van Allen EM, Geynisman DM, Parker DC, O'Neill JP, Drevik J, Christianson SS, Ginzburg S, Correa AF, Uzzo RG, Ross EA, Zibelman MR, Ghatalia P, Plimack ER, Kutikov A, Abbosh PH
published in: JCO precision oncology
information resource reference: Urine Biopsy as Dynamic Biomarker to Enhance Clinical Staging of Bladder Cancer in Radical Cystectomy Candidates. JCO Precis Oncol. 2024 06; 8:e2300362.
journal title abbreviation: JCO Precis Oncol
publication date: 2024-06-01T00:00:00
year: 2024
type: Academic Article
type: Article
type: Document
type: Information Resource

AI and immunology.
PubMed Identifier: 38865960
author list: Germain RN, Van Allen EM, Trynka G, Tsang JS, Grün D, Kiemen AL, Shi Y, Pugh Bernard A, Nolan GP
published in: Immunity
information resource reference: AI and immunology. Immunity. 2024 06 11; 57(6):1177-1181.
journal title abbreviation: Immunity
publication date: 2024-06-11T00:00:00
year: 2024
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1665125
type: Authorship
author rank in publication: 35
linked author: Van Allen, Eliezer
linked information resource: Mechanisms of Resistance to Oncogenic KRAS Inhibition in Pancreatic Cancer.

Mechanisms of Resistance to Oncogenic KRAS Inhibition in Pancreatic Cancer.
PubMed Identifier: 38975874
author list: Dilly J, Hoffman MT, Abbassi L, Li Z, Paradiso F, Parent BD, Hennessey CJ, Jordan AC, Morgado M, Dasgupta S, Uribe GA, Yang A, Kapner KS, Hambitzer FP, Qiang L, Feng H, Geisberg J, Wang J, Evans KE, Lyu H, Schalck A, Feng N, Lopez AM, Bristow CA, Kim MP, Rajapakshe KI, Bahrambeigi V, Roth JA, Garg K, Guerrero PA, Stanger BZ, Cristea S, Lowe SW, Baslan T, Van Allen EM, Mancias JD, Chan E, Anderson A, Katlinskaya YV, Shalek AK, Hong DS, Pant S, Hallin J, Anderes K, Olson P, Heffernan TP, Chugh S, Christensen JG, Maitra A, Wolpin BM, Raghavan S, Nowak JA, Winter PS, Dougan SK, Aguirre AJ
published in: Cancer discovery
information resource reference: Mechanisms of Resistance to Oncogenic KRAS Inhibition in Pancreatic Cancer. Cancer Discov. 2024 Nov 01; 14(11):2135-2161.
journal title abbreviation: Cancer Discov
publication date: 2024-11-01T00:00:00
year: 2024
type: Academic Article
type: Article
type: Document
type: Information Resource

Professor of Medicine
is primary position: true
position in department: Medicine
position in division: Hematology/Oncology
sort order: 1
type: Position
HR job title: Professor of Medicine
position in organization: Massachusetts General Hospital

Professor of Medicine
is primary position: true
position in department: Medicine
position in division: Oncology
sort order: 1
type: Position
HR job title: Professor of Medicine
position in organization: Dana-Farber Cancer Institute

Assistant Professor of Medicine
is primary position: true
position in department: Medicine
position in division: Oncology
sort order: 1
type: Position
HR job title: Assistant Professor of Medicine
position in organization: Dana-Farber Cancer Institute

Jerome and Nancy Kohlberg Professor of Medicine
is primary position: true
position in department: Medicine
position in division: Oncology
sort order: 1
type: Position
HR job title: Jerome and Nancy Kohlberg Professor of Medicine
position in organization: Dana-Farber Cancer Institute

Authorship 1677965
type: Authorship
author rank in publication: 21
linked author: Van Allen, Eliezer
linked information resource: ESMO Recommendations on clinical reporting of genomic test results for solid cancers.

ESMO Recommendations on clinical reporting of genomic test results for solid cancers.
PubMed Identifier: 39112111
author list: van de Haar J, Roepman P, Andre F, Balmaña J, Castro E, Chakravarty D, Curigliano G, Czarnecka AM, Dienstmann R, Horak P, Italiano A, Marchiò C, Monkhorst K, Pritchard CC, Reardon B, Russnes HEG, Sirohi B, Sosinsky A, Spanic T, Turnbull C, Van Allen E, Westphalen CB, Tamborero D, Mateo J
published in: Annals of oncology : official journal of the European Society for Medical Oncology
information resource reference: ESMO Recommendations on clinical reporting of genomic test results for solid cancers. Ann Oncol. 2024 Nov; 35(11):954-967.
journal title abbreviation: Ann Oncol
publication date: 2024-07-09T00:00:00
year: 2024
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1688849
type: Authorship
author rank in publication: 22
linked author: Van Allen, Eliezer
linked information resource: Cell states and neighborhoods in distinct clinical stages of primary and metastatic esophageal adenocarcinoma.

Cell states and neighborhoods in distinct clinical stages of primary and metastatic esophageal adenocarcinoma.
PubMed Identifier: 39229240
author list: Yates J, Mathey-Andrews C, Park J, Garza A, Gagné A, Hoffman S, Bi K, Titchen B, Hennessey C, Remland J, Shannon E, Camp S, Balamurali S, Cavale SK, Li Z, Raghawan AK, Kraft A, Boland G, Aguirre AJ, Sethi NS, Boeva V, Van Allen E
published in: bioRxiv : the preprint server for biology
information resource reference: Cell states and neighborhoods in distinct clinical stages of primary and metastatic esophageal adenocarcinoma. bioRxiv. 2025 Mar 03.
journal title abbreviation: bioRxiv
publication date: 2025-03-03T00:00:00
year: 2025
type: Academic Article
type: Article
type: Document
type: Information Resource

Germline polygenic risk scores are associated with immune gene expression signature and immune cell infiltration in breast cancer.
PubMed Identifier: 39270649
author list: Liu Y, Peng C, Brorson IS, O'Mahony DG, Kelly RL, Heng YJ, Baker GM, Grenaker Alnæs GI, Bodelon C, Stover DG, Van Allen EM, Eliassen AH, Kristensen VN, Tamimi RM, Kraft P
published in: American journal of human genetics
information resource reference: Germline polygenic risk scores are associated with immune gene expression signature and immune cell infiltration in breast cancer. Am J Hum Genet. 2024 Oct 03; 111(10):2150-2163.
journal title abbreviation: Am J Hum Genet
publication date: 2024-09-12T00:00:00
year: 2024
type: Academic Article
type: Article
type: Document
type: Information Resource

Toward a CRISPR-based mouse model of Vhl-deficient clear cell kidney cancer: Initial experience and lessons learned.
PubMed Identifier: 39365820
author list: Stransky LA, Gao W, Schmidt LS, Bi K, Ricketts CJ, Ramesh V, James A, Difilippantonio S, Ileva L, Kalen JD, Karim B, Jeon A, Morgan T, Warner AC, Turan S, Unite J, Tran B, Choudhari S, Zhao Y, Linn DE, Yun C, Dhandapani S, Parab V, Pinheiro EM, Morris N, He L, Vigeant SM, Pignon JC, Sticco-Ivins M, Signoretti S, Van Allen EM, Linehan WM, Kaelin WG
published in: Proceedings of the National Academy of Sciences of the United States of America
information resource reference: Toward a CRISPR-based mouse model of Vhl-deficient clear cell kidney cancer: Initial experience and lessons learned. Proc Natl Acad Sci U S A. 2024 Oct 08; 121(41):e2408549121.
journal title abbreviation: Proc Natl Acad Sci U S A
publication date: 2024-10-04T00:00:00
year: 2024
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1697145
type: Authorship
author rank in publication: 15
linked author: Van Allen, Eliezer
linked information resource: A New Era of Data-Driven Cancer Research and Care: Opportunities and Challenges.

Authorship 1697955
type: Authorship
author rank in publication: 19
linked author: Van Allen, Eliezer
linked information resource: Dual Immune Checkpoint Inhibition in Patients With Aggressive Thyroid Carcinoma: A Phase 2 Nonrandomized Clinical Trial.

Authorship 1697204
type: Authorship
author rank in publication: 31
linked author: Van Allen, Eliezer
linked information resource: Toward a CRISPR-based mouse model of Vhl-deficient clear cell kidney cancer: Initial experience and lessons learned.

Authorship 1699719
type: Authorship
author rank in publication: 11
linked author: Van Allen, Eliezer
linked information resource: Germline polygenic risk scores are associated with immune gene expression signature and immune cell infiltration in breast cancer.

Authorship 1695650
type: Authorship
author rank in publication: 56
linked author: Van Allen, Eliezer
linked information resource: CTLA4 blockade abrogates KEAP1/STK11-related resistance to PD-(L)1 inhibitors.

A New Era of Data-Driven Cancer Research and Care: Opportunities and Challenges.
PubMed Identifier: 39363742
author list: Gomez F, Danos AM, Del Fiol G, Madabhushi A, Tiwari P, McMichael JF, Bakas S, Bian J, Davatzikos C, Fertig EJ, Kalpathy-Cramer J, Kenney J, Savova GK, Yetisgen M, Van Allen EM, Warner JL, Prior F, Griffith M, Griffith OL
published in: Cancer discovery
information resource reference: A New Era of Data-Driven Cancer Research and Care: Opportunities and Challenges. Cancer Discov. 2024 Oct 04; 14(10):1774-1778.
journal title abbreviation: Cancer Discov
publication date: 2024-10-04T00:00:00
year: 2024
type: Academic Article
type: Article
type: Document
type: Information Resource

Dual Immune Checkpoint Inhibition in Patients With Aggressive Thyroid Carcinoma: A Phase 2 Nonrandomized Clinical Trial.
PubMed Identifier: 39446365
author list: Sehgal K, Pappa T, Shin KY, Schiantarelli J, Liu M, Ricker C, Besson NR, Jones SM, Welsh EL, Pfaff KL, Barletta JA, Park J, Reardon B, Doherty GM, Alexander EK, Rodig SJ, Barbie DA, O'Neill A, Van Allen E, Haddad RI, Lorch JH
published in: JAMA oncology
information resource reference: Dual Immune Checkpoint Inhibition in Patients With Aggressive Thyroid Carcinoma: A Phase 2 Nonrandomized Clinical Trial. JAMA Oncol. 2024 12 01; 10(12):1663-1671.
journal title abbreviation: JAMA Oncol
publication date: 2024-12-01T00:00:00
year: 2024
type: Academic Article
type: Article
type: Document
type: Information Resource

CTLA4 blockade abrogates KEAP1/STK11-related resistance to PD-(L)1 inhibitors.
PubMed Identifier: 39385035
author list: Skoulidis F, Araujo HA, Do MT, Qian Y, Sun X, Galan-Cobo A, Le JT, Montesion M, Palmer R, Jahchan N, Juan JM, Min C, Yu Y, Pan X, Arbour KC, Vokes N, Schmidt ST, Molkentine D, Owen DH, Memmott R, Patil PD, Marmarelis ME, Awad MM, Murray JC, Hellyer JA, Gainor JF, Dimou A, Bestvina CM, Shu CA, Riess JW, Blakely CM, Pecot CV, Mezquita L, Tabbó F, Scheffler M, Digumarthy S, Mooradian MJ, Sacher AG, Lau SCM, Saltos AN, Rotow J, Johnson RP, Liu C, Stewart T, Goldberg SB, Killam J, Walther Z, Schalper K, Davies KD, Woodcock MG, Anagnostou V, Marrone KA, Forde PM, Ricciuti B, Venkatraman D, Van Allen EM, Cummings AL, Goldman JW, Shaish H, Kier M, Katz S, Aggarwal C, Ni Y, Azok JT, Segal J, Ritterhouse L, Neal JW, Lacroix L, Elamin YY, Negrao MV, Le X, Lam VK, Lewis WE, Kemp HN, Carter B, Roth JA, Swisher S, Lee R, Zhou T, Poteete A, Kong Y, Takehara T, Paula AG, Parra Cuentas ER, Behrens C, Wistuba II, Zhang J, Blumenschein GR, Gay C, Byers LA, Gibbons DL, Tsao A, Lee JJ, Bivona TG, Camidge DR, Gray JE, Leighl NB, Levy B, Brahmer JR, Garassino MC, Gandara DR, Garon EB, Rizvi NA, Scagliotti GV, Wolf J, Planchard D, Besse B, Herbst RS, Wakelee HA, Pennell NA, Shaw AT, Jänne PA, Carbone DP, Hellmann MD, Rudin CM, Albacker L, Mann H, Zhu Z, Lai Z, Stewart R, Peters S, Johnson ML, Wong KK, Huang A, Winslow MM, Rosen MJ, Winters IP, Papadimitrakopoulou VA, Cascone T, Jewsbury P, Heymach JV
published in: Nature
information resource reference: CTLA4 blockade abrogates KEAP1/STK11-related resistance to PD-(L)1 inhibitors. Nature. 2024 11; 635(8038):462-471.
journal title abbreviation: Nature
publication date: 2024-10-09T00:00:00
year: 2024
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1703491
type: Authorship
author rank in publication: 25
linked author: Van Allen, Eliezer
linked information resource: Ten challenges and opportunities in computational immuno-oncology.

Ten challenges and opportunities in computational immuno-oncology.
PubMed Identifier: 39461879
author list: Bao R, Hutson A, Madabhushi A, Jonsson VD, Rosario SR, Barnholtz-Sloan JS, Fertig EJ, Marathe H, Harris L, Altreuter J, Chen Q, Dignam J, Gentles AJ, Gonzalez-Kozlova E, Gnjatic S, Kim E, Long M, Morgan M, Ruppin E, Valen DV, Zhang H, Vokes N, Meerzaman D, Liu S, Van Allen EM, Xing Y
published in: Journal for immunotherapy of cancer
information resource reference: Ten challenges and opportunities in computational immuno-oncology. J Immunother Cancer. 2024 Oct 26; 12(10).
journal title abbreviation: J Immunother Cancer
publication date: 2024-10-26T00:00:00
year: 2024
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1709506
type: Authorship
author rank in publication: 24
linked author: Van Allen, Eliezer
linked information resource: Single-cell epigenetic profiling reveals an interferon response-high program associated with BAP1 deficiency in kidney cancer.

Authorship 1708768
type: Authorship
author rank in publication: 37
linked author: Van Allen, Eliezer
linked information resource: Genomic heterogeneity and ploidy identify patients with intrinsic resistance to PD-1 blockade in metastatic melanoma.

Genomic heterogeneity and ploidy identify patients with intrinsic resistance to PD-1 blockade in metastatic melanoma.
PubMed Identifier: 39602539
author list: Tarantino G, Ricker CA, Wang A, Ge W, Aprati TJ, Huang AY, Madha S, Chen J, Shi Y, Glettig M, Feng CH, Frederick DT, Freeman S, Holovatska MM, Manos MP, Zimmer L, Rösch A, Zaremba A, Livingstone E, Jameson JC, Saghafian S, Lee A, Zhao K, Morris LGT, Reardon B, Park J, Elmarakeby HA, Schilling B, Giobbie-Hurder A, Vokes NI, Buchbinder EI, Flaherty KT, Haq R, Wu CJ, Boland GM, Hodi FS, Van Allen EM, Schadendorf D, Liu D
published in: Science advances
information resource reference: Genomic heterogeneity and ploidy identify patients with intrinsic resistance to PD-1 blockade in metastatic melanoma. Sci Adv. 2024 11 29; 10(48):eadp4670.
journal title abbreviation: Sci Adv
publication date: 2024-11-27T00:00:00
year: 2024
type: Academic Article
type: Article
type: Document
type: Information Resource

Single-cell epigenetic profiling reveals an interferon response-high program associated with BAP1 deficiency in kidney cancer.
PubMed Identifier: 39605676
author list: Camp SY, He MX, Cuoco MS, Saad E, Pimenta E, Meli K, Bakouny Z, Labaki C, Titchen BM, Kang YJ, Horst J, Trowbridge R, Shannon E, Helvie K, Thorner AR, Vigneau S, Mayorga A, Kodali J, Lachmayr H, Bemus M, Park J, Choueiri T, Bi K, Van Allen EM
published in: bioRxiv : the preprint server for biology
information resource reference: Single-cell epigenetic profiling reveals an interferon response-high program associated with BAP1 deficiency in kidney cancer. bioRxiv. 2024 Nov 18.
journal title abbreviation: bioRxiv
publication date: 2024-11-18T00:00:00
year: 2024
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1710657
type: Authorship
author rank in publication: 16
linked author: Van Allen, Eliezer
linked information resource: Evolution of myeloid-mediated immunotherapy resistance in prostate cancer.

Evolution of myeloid-mediated immunotherapy resistance in prostate cancer.
PubMed Identifier: 39633050
author list: Lyu A, Fan Z, Clark M, Lea A, Luong D, Setayesh A, Starzinski A, Wolters R, Arias-Badia M, Allaire K, Wu K, Gurunathan V, Valderrábano L, Wei XX, Miller RA, Van Allen EM, Fong L
published in: Nature
information resource reference: Evolution of myeloid-mediated immunotherapy resistance in prostate cancer. Nature. 2025 01; 637(8048):1207-1217.
journal title abbreviation: Nature
publication date: 2024-12-04T00:00:00
year: 2024
type: Academic Article
type: Article
type: Document
type: Information Resource

An evaluation framework for clinical use of large language models in patient interaction tasks.
PubMed Identifier: 39747685
author list: Johri S, Jeong J, Tran BA, Schlessinger DI, Wongvibulsin S, Barnes LA, Zhou HY, Cai ZR, Van Allen EM, Kim D, Daneshjou R, Rajpurkar P
published in: Nature medicine
information resource reference: An evaluation framework for clinical use of large language models in patient interaction tasks. Nat Med. 2025 Jan; 31(1):77-86.
journal title abbreviation: Nat Med
publication date: 2025-01-02T00:00:00
year: 2025
type: Academic Article
type: Article
type: Document
type: Information Resource

Rare germline structural variants increase risk for pediatric solid tumors.
PubMed Identifier: 39745975
author list: Gillani R, Collins RL, Crowdis J, Garza A, Jones JK, Walker M, Sanchis-Juan A, Whelan CW, Pierce-Hoffman E, Talkowski ME, Brand H, Haigis K, LoPiccolo J, AlDubayan SH, Gusev A, Crompton BD, Janeway KA, Van Allen EM
published in: Science (New York, N.Y.)
information resource reference: Rare germline structural variants increase risk for pediatric solid tumors. Science. 2025 01 03; 387(6729):eadq0071.
journal title abbreviation: Science
publication date: 2025-01-03T00:00:00
year: 2025
type: Academic Article
type: Article
type: Document
type: Information Resource

Immunogenomic determinants of exceptional response to immune checkpoint inhibition in renal cell carcinoma.
PubMed Identifier: 39789182
author list: Jammihal T, Saliby RM, Labaki C, Soulati H, Gallegos J, Peris A, McCurry D, Yu C, Shah V, Poduval D, El Zarif T, El Ahmar N, Laimon YN, Eid M, Sheshdeh AB, Krajewski KM, Büttner FA, Schwab M, Heng D, Casellas RC, Rai K, Zacharias Millward NM, Msaouel P, Karam J, Signoretti S, Van Allen E, Choueiri TK, Braun DA, Shukla SA
published in: Nature cancer
information resource reference: Immunogenomic determinants of exceptional response to immune checkpoint inhibition in renal cell carcinoma. Nat Cancer. 2025 Feb; 6(2):372-384.
journal title abbreviation: Nat Cancer
publication date: 2025-01-09T00:00:00
year: 2025
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1717275
type: Authorship
author rank in publication: 9
linked author: Van Allen, Eliezer
linked information resource: An evaluation framework for clinical use of large language models in patient interaction tasks.

Authorship 1717890
type: Authorship
author rank in publication: 26
linked author: Van Allen, Eliezer
linked information resource: Immunogenomic determinants of exceptional response to immune checkpoint inhibition in renal cell carcinoma.

Authorship 1717155
type: Authorship
author rank in publication: 18
linked author: Van Allen, Eliezer
linked information resource: Rare germline structural variants increase risk for pediatric solid tumors.

HIF regulates multiple translated endogenous retroviruses: Implications for cancer immunotherapy.
PubMed Identifier: 40023154
author list: Jiang Q, Braun DA, Clauser KR, Ramesh V, Shirole NH, Duke-Cohan JE, Nabilsi N, Kramer NJ, Forman C, Lippincott IE, Klaeger S, Phulphagar KM, Chea V, Kim N, Vanasse AP, Saad E, Parsons T, Carr-Reynolds M, Carulli I, Pinjusic K, Jiang Y, Li R, Syamala S, Rachimi S, Verzani EK, Stevens JD, Lane WJ, Camp SY, Meli K, Pappalardi MB, Herbert ZT, Qiu X, Cejas P, Long HW, Shukla SA, Van Allen EM, Choueiri TK, Churchman LS, Abelin JG, Gurer C, MacBeath G, Childs RW, Carr SA, Keskin DB, Wu CJ, Kaelin WG
published in: Cell
information resource reference: HIF regulates multiple translated endogenous retroviruses: Implications for cancer immunotherapy. Cell. 2025 Apr 03; 188(7):1807-1827.e34.
journal title abbreviation: Cell
publication date: 2025-02-28T00:00:00
year: 2025
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 678983
type: Authorship
author rank in publication: 12
linked author: Van Allen, Eliezer
linked information resource: A survey of informatics approaches to whole-exome and whole-genome clinical reporting in the electronic health record.

A survey of informatics approaches to whole-exome and whole-genome clinical reporting in the electronic health record.
PubMed Identifier: 24071794
author list: Tarczy-Hornoch P, Amendola L, Aronson SJ, Garraway L, Gray S, Grundmeier RW, Hindorff LA, Jarvik G, Karavite D, Lebo M, Plon SE, Van Allen E, Weck KE, White PS, Yang Y
published in: Genetics in medicine : official journal of the American College of Medical Genetics
information resource reference: A survey of informatics approaches to whole-exome and whole-genome clinical reporting in the electronic health record. Genet Med. 2013 Oct; 15(10):824-32.
journal title abbreviation: Genet Med
publication date: 2013-09-26T00:00:00
year: 2013
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1736798
type: Authorship
author rank in publication: 56
linked author: Van Allen, Eliezer
linked information resource: Author Correction: CTLA4 blockade abrogates KEAP1/STK11-related resistance to PD-(L)1 inhibitors.

Authorship 1733603
type: Authorship
author rank in publication: 22
linked author: Van Allen, Eliezer
linked information resource: Epigenetic dysregulation of metabolic programs mediates liposarcoma cell plasticity.

Authorship 1734705
type: Authorship
author rank in publication: 14
linked author: Van Allen, Eliezer
linked information resource: Genomic mediators of acquired resistance to immunotherapy in metastatic melanoma.

Authorship 1730894
type: Authorship
author rank in publication: 36
linked author: Van Allen, Eliezer
linked information resource: HIF regulates multiple translated endogenous retroviruses: Implications for cancer immunotherapy.

Authorship 1731043
type: Authorship
author rank in publication: 13
linked author: Van Allen, Eliezer
linked information resource: Dissecting tumor cell programs through group biology estimation in clinical single-cell transcriptomics.

Genomic mediators of acquired resistance to immunotherapy in metastatic melanoma.
PubMed Identifier: 39933900
author list: Schiantarelli J, Benamar M, Park J, Sax HE, Oliveira G, Bosma-Moody A, Campbell KM, Liu D, Johnson DB, Rodig S, Wu CJ, Hodi FS, Ribas A, Van Allen E, Haq R
published in: Cancer cell
information resource reference: Genomic mediators of acquired resistance to immunotherapy in metastatic melanoma. Cancer Cell. 2025 Feb 10; 43(2):308-316.e6.
journal title abbreviation: Cancer Cell
publication date: 2025-02-10T00:00:00
year: 2025
type: Academic Article
type: Article
type: Document
type: Information Resource

Author Correction: CTLA4 blockade abrogates KEAP1/STK11-related resistance to PD-(L)1 inhibitors.
PubMed Identifier: 40016449
author list: Skoulidis F, Araujo HA, Do MT, Qian Y, Sun X, Cobo AG, Le JT, Montesion M, Palmer R, Jahchan N, Juan JM, Min C, Yu Y, Pan X, Arbour KC, Vokes N, Schmidt ST, Molkentine D, Owen DH, Memmott R, Patil PD, Marmarelis ME, Awad MM, Murray JC, Hellyer JA, Gainor JF, Dimou A, Bestvina CM, Shu CA, Riess JW, Blakely CM, Pecot CV, Mezquita L, Tabbó F, Scheffler M, Digumarthy S, Mooradian MJ, Sacher AG, Lau SCM, Saltos AN, Rotow J, Johnson RP, Liu C, Stewart T, Goldberg SB, Killam J, Walther Z, Schalper K, Davies KD, Woodcock MG, Anagnostou V, Marrone KA, Forde PM, Ricciuti B, Venkatraman D, Van Allen EM, Cummings AL, Goldman JW, Shaish H, Kier M, Katz S, Aggarwal C, Ni Y, Azok JT, Segal J, Ritterhouse L, Neal JW, Lacroix L, Elamin YY, Negrao MV, Le X, Lam VK, Lewis WE, Kemp HN, Carter B, Roth JA, Swisher S, Lee R, Zhou T, Poteete A, Kong Y, Takehara T, Paula AG, Parra Cuentas ER, Behrens C, Wistuba II, Zhang J, Blumenschein GR, Gay C, Byers LA, Gibbons DL, Tsao A, Lee JJ, Bivona TG, Camidge DR, Gray JE, Leighl NB, Levy B, Brahmer JR, Garassino MC, Gandara DR, Garon EB, Rizvi NA, Scagliotti GV, Wolf J, Planchard D, Besse B, Herbst RS, Wakelee HA, Pennell NA, Shaw AT, Jänne PA, Carbone DP, Hellmann MD, Rudin CM, Albacker L, Mann H, Zhu Z, Lai Z, Stewart R, Peters S, Johnson ML, Wong KK, Huang A, Winslow MM, Rosen MJ, Winters IP, Papadimitrakopoulou VA, Cascone T, Jewsbury P, Heymach JV
published in: Nature
information resource reference: Author Correction: CTLA4 blockade abrogates KEAP1/STK11-related resistance to PD-(L)1 inhibitors. Nature. 2025 Mar; 639(8054):E19.
journal title abbreviation: Nature
publication date: 2025-03-01T00:00:00
year: 2025
type: Academic Article
type: Article
type: Document
type: Information Resource

Dissecting tumor cell programs through group biology estimation in clinical single-cell transcriptomics.
PubMed Identifier: 40025015
author list: Johri S, Bi K, Titchen BM, Fu J, Conway J, Crowdis JP, Vokes NI, Fan Z, Fong L, Park J, Liu D, He MX, Van Allen EM
published in: Nature communications
information resource reference: Dissecting tumor cell programs through group biology estimation in clinical single-cell transcriptomics. Nat Commun. 2025 Mar 01; 16(1):2090.
journal title abbreviation: Nat Commun
publication date: 2025-03-01T00:00:00
year: 2025
type: Academic Article
type: Article
type: Document
type: Information Resource

Epigenetic dysregulation of metabolic programs mediates liposarcoma cell plasticity.
PubMed Identifier: 39896505
author list: Pimenta EM, Garza AE, Camp SY, Park J, Hoffman SE, Valderrábano L, Fu J, Bi K, Karam J, Titchen BM, Khandekar MJ, Shannon E, Kang YJ, Nag A, Thorner AR, Raut CP, Hornick JL, Merriam P, Solimini NL, George S, Demetri GD, Van Allen EM
published in: bioRxiv : the preprint server for biology
information resource reference: Epigenetic dysregulation of metabolic programs mediates liposarcoma cell plasticity. bioRxiv. 2025 Jan 24.
journal title abbreviation: bioRxiv
publication date: 2025-01-24T00:00:00
year: 2025
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 690753
type: Authorship
author rank in publication: 3
linked author: Van Allen, Eliezer
linked information resource: A phase II trial of AS1411 (a novel nucleolin-targeted DNA aptamer) in metastatic renal cell carcinoma.

A phase II trial of AS1411 (a novel nucleolin-targeted DNA aptamer) in metastatic renal cell carcinoma.
PubMed Identifier: 24242861
author list: Rosenberg JE, Bambury RM, Van Allen EM, Drabkin HA, Lara PN, Harzstark AL, Wagle N, Figlin RA, Smith GW, Garraway LA, Choueiri T, Erlandsson F, Laber DA
published in: Investigational new drugs
information resource reference: A phase II trial of AS1411 (a novel nucleolin-targeted DNA aptamer) in metastatic renal cell carcinoma. Invest New Drugs. 2014 Feb; 32(1):178-87.
journal title abbreviation: Invest New Drugs
publication date: 2013-11-16T00:00:00
year: 2013
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 197848
type: Authorship
author rank in publication: 1
linked author: Van Allen, Eliezer
linked information resource: A role in transition.

Processes and preliminary outputs for identification of actionable genes as incidental findings in genomic sequence data in the Clinical Sequencing Exploratory Research Consortium.
PubMed Identifier: 24195999
author list: Berg JS, Amendola LM, Eng C, Van Allen E, Gray SW, Wagle N, Rehm HL, DeChene ET, Dulik MC, Hisama FM, Burke W, Spinner NB, Garraway L, Green RC, Plon S, Evans JP, Jarvik GP
published in: Genetics in medicine : official journal of the American College of Medical Genetics
information resource reference: Processes and preliminary outputs for identification of actionable genes as incidental findings in genomic sequence data in the Clinical Sequencing Exploratory Research Consortium. Genet Med. 2013 Nov; 15(11):860-7.
journal title abbreviation: Genet Med
publication date: 2013-10-24T00:00:00
year: 2013
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 693233
type: Authorship
author rank in publication: 2
linked author: Van Allen, Eliezer
linked information resource: MAP kinase pathway alterations in BRAF-mutant melanoma patients with acquired resistance to combined RAF/MEK inhibition.

Authorship 693234
type: Authorship
author rank in publication: 1
linked author: Van Allen, Eliezer
linked information resource: The genetic landscape of clinical resistance to RAF inhibition in metastatic melanoma.

The genetic landscape of clinical resistance to RAF inhibition in metastatic melanoma.
PubMed Identifier: 24265153
author list: Van Allen EM, Wagle N, Sucker A, Treacy DJ, Johannessen CM, Goetz EM, Place CS, Taylor-Weiner A, Whittaker S, Kryukov GV, Hodis E, Rosenberg M, McKenna A, Cibulskis K, Farlow D, Zimmer L, Hillen U, Gutzmer R, Goldinger SM, Ugurel S, Gogas HJ, Egberts F, Berking C, Trefzer U, Loquai C, Weide B, Hassel JC, Gabriel SB, Carter SL, Getz G, Garraway LA, Schadendorf D
published in: Cancer discovery
information resource reference: The genetic landscape of clinical resistance to RAF inhibition in metastatic melanoma. Cancer Discov. 2014 Jan; 4(1):94-109.
journal title abbreviation: Cancer Discov
publication date: 2013-11-21T00:00:00
year: 2013
type: Academic Article
type: Article
type: Document
type: Information Resource

MAP kinase pathway alterations in BRAF-mutant melanoma patients with acquired resistance to combined RAF/MEK inhibition.
PubMed Identifier: 24265154
author list: Wagle N, Van Allen EM, Treacy DJ, Frederick DT, Cooper ZA, Taylor-Weiner A, Rosenberg M, Goetz EM, Sullivan RJ, Farlow DN, Friedrich DC, Anderka K, Perrin D, Johannessen CM, McKenna A, Cibulskis K, Kryukov G, Hodis E, Lawrence DP, Fisher S, Getz G, Gabriel SB, Carter SL, Flaherty KT, Wargo JA, Garraway LA
published in: Cancer discovery
information resource reference: MAP kinase pathway alterations in BRAF-mutant melanoma patients with acquired resistance to combined RAF/MEK inhibition. Cancer Discov. 2014 Jan; 4(1):61-8.
journal title abbreviation: Cancer Discov
publication date: 2013-11-21T00:00:00
year: 2013
type: Academic Article
type: Article
type: Document
type: Information Resource

Lecturer on Medicine, Part-time
is primary position: true
position in department: Medicine
position in division: Channing Division of Network Medicine
sort order: 1
type: Position
HR job title: Lecturer on Medicine, Part-time
position in organization: Brigham and Women's Hospital

Instructor in Medicine
is primary position: true
position in department: Medicine
position in division: Oncology
sort order: 1
type: Position
HR job title: Instructor in Medicine
position in organization: Dana-Farber Cancer Institute

Assistant Professor of Pediatrics
is primary position: true
position in department: Pediatrics
position in division: DFCI
sort order: 1
type: Position
HR job title: Assistant Professor of Pediatrics
position in organization: Dana-Farber Cancer Institute

Authorship 1749747
type: Authorship
author rank in publication: 2
linked author: Van Allen, Eliezer
linked information resource: New horizons at the interface of artificial intelligence and translational cancer research.

New horizons at the interface of artificial intelligence and translational cancer research.
PubMed Identifier: 40233719
author list: Yates J, Van Allen EM
published in: Cancer cell
information resource reference: New horizons at the interface of artificial intelligence and translational cancer research. Cancer Cell. 2025 Apr 14; 43(4):708-727.
journal title abbreviation: Cancer Cell
publication date: 2025-04-14T00:00:00
year: 2025
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 699834
type: Authorship
author rank in publication: 1
linked author: Van Allen, Eliezer
linked information resource: Successful whole-exome sequencing from a prostate cancer bone metastasis biopsy.

Authorship 699835
type: Authorship
author rank in publication: 4
linked author: Van Allen, Eliezer
linked information resource: Processes and preliminary outputs for identification of actionable genes as incidental findings in genomic sequence data in the Clinical Sequencing Exploratory Research Consortium.

Successful whole-exome sequencing from a prostate cancer bone metastasis biopsy.
PubMed Identifier: 24366412
author list: Van Allen EM, Foye A, Wagle N, Kim W, Carter SL, McKenna A, Simko JP, Garraway LA, Febbo PG
published in: Prostate cancer and prostatic diseases
information resource reference: Successful whole-exome sequencing from a prostate cancer bone metastasis biopsy. Prostate Cancer Prostatic Dis. 2014 Mar; 17(1):23-7.
journal title abbreviation: Prostate Cancer Prostatic Dis
publication date: 2013-12-24T00:00:00
year: 2013
type: Academic Article
type: Article
type: Document
type: Information Resource

Professor of Medicine
is primary position: true
position in department: Medicine
position in division: Oncology
sort order: 1
type: Position
HR job title: Professor of Medicine
position in organization: Dana-Farber Cancer Institute

Research Associate in Medicine
is primary position: true
position in department: Medicine
position in division: Oncology
sort order: 1
type: Position
HR job title: Research Associate in Medicine
position in organization: Dana-Farber Cancer Institute

Whole-exome sequencing of circulating tumor cells provides a window into metastatic prostate cancer.
PubMed Identifier: 24752078
author list: Lohr JG, Adalsteinsson VA, Cibulskis K, Choudhury AD, Rosenberg M, Cruz-Gordillo P, Francis JM, Zhang CZ, Shalek AK, Satija R, Trombetta JJ, Lu D, Tallapragada N, Tahirova N, Kim S, Blumenstiel B, Sougnez C, Lowe A, Wong B, Auclair D, Van Allen EM, Nakabayashi M, Lis RT, Lee GS, Li T, Chabot MS, Ly A, Taplin ME, Clancy TE, Loda M, Regev A, Meyerson M, Hahn WC, Kantoff PW, Golub TR, Getz G, Boehm JS, Love JC
published in: Nature biotechnology
information resource reference: Whole-exome sequencing of circulating tumor cells provides a window into metastatic prostate cancer. Nat Biotechnol. 2014 May; 32(5):479-84.
journal title abbreviation: Nat Biotechnol
publication date: 2014-04-20T00:00:00
year: 2014
type: Academic Article
type: Article
type: Document
type: Information Resource

Efficacy, safety, and predictive biomarkers of neoadjuvant nab-paclitaxel and pembrolizumab in hormone receptor-positive breast cancer: A randomized pilot trial.
PubMed Identifier: 41315271
author list: Waks AG, Fu J, Chu X, Binboga Kurt B, Li T, Kuntz TM, Shen Y, Yang D, Meli K, Reardon B, Park J, Partridge A, Abravanel D, Jeselsohn R, Wrabel E, Alberti J, DiLullo M, Chen S, Mohammed-Abreu A, Sun X, Balko JM, Kleijn M, Audeh W, Morgan XC, Krop IE, Tayob N, Van Allen EM, Mittendorf EA, Tolaney SM
published in: Nature communications
information resource reference: Efficacy, safety, and predictive biomarkers of neoadjuvant nab-paclitaxel and pembrolizumab in hormone receptor-positive breast cancer: A randomized pilot trial. Nat Commun. 2025 Nov 28; 16(1):10705.
journal title abbreviation: Nat Commun
publication date: 2025-11-28T00:00:00
year: 2025
type: Academic Article
type: Article
type: Document
type: Information Resource

Professor of Medicine
is primary position: true
position in department: Medicine
position in division: Oncology
sort order: 1
type: Position
HR job title: Professor of Medicine
position in organization: Dana-Farber Cancer Institute

Disruption of Microhomology-mediated End-joining in Ewing Sarcoma.
PubMed Identifier: 40568108
author list: Asada S, Zhu G, Abeykoon JP, Tanaka Y, Nguyen H, Hirohashi Y, Iyer DR, Ashton NW, Mukkavalli S, Velazquez M, Jiang L, Busso MD, Thangaiah JJ, Robinson SI, Parmar K, Van Allen EM, Gillani R, Shapiro GI, D'Andrea AD
published in: bioRxiv : the preprint server for biology
information resource reference: Disruption of Microhomology-mediated End-joining in Ewing Sarcoma. bioRxiv. 2025 Sep 18.
journal title abbreviation: bioRxiv
publication date: 2025-09-18T00:00:00
year: 2025
type: Academic Article
type: Article
type: Document
type: Information Resource

Conserved Neuronal-like and Secretory Programs Define the Spatial Architecture of Gastroenteropancreatic Neuroendocrine Tumors.
PubMed Identifier: 41509223
author list: Karam J, Hoffman SE, Garza A, Gui D, Hoffman HI, Titchen BM, Tanaka Y, Pimenta E, Pappa T, Valderrabano L, Bi K, Gillani R, Brais L, Shannon E, Hornick JL, Park J, Chan J, Van Allen EM
published in: bioRxiv : the preprint server for biology
information resource reference: Conserved Neuronal-like and Secretory Programs Define the Spatial Architecture of Gastroenteropancreatic Neuroendocrine Tumors. bioRxiv. 2025 Dec 29.
journal title abbreviation: bioRxiv
publication date: 2025-12-29T00:00:00
year: 2025
type: Academic Article
type: Article
type: Document
type: Information Resource

Implementing a context-augmented large language model to guide precision cancer medicine.
PubMed Identifier: 40778147
author list: Jun H, Tanaka Y, Johri S, Carvalho FL, Jordan AC, Labaki C, Nagy M, O'Meara TA, Pappa T, Pimenta EM, Saad E, Yang DD, Gillani R, Tewari AK, Reardon B, Van Allen E
published in: medRxiv : the preprint server for health sciences
information resource reference: Implementing a context-augmented large language model to guide precision cancer medicine. medRxiv. 2025 Jul 24.
journal title abbreviation: medRxiv
publication date: 2025-07-24T00:00:00
year: 2025
type: Academic Article
type: Article
type: Document
type: Information Resource

Associate Professor of Medicine
is primary position: true
position in department: Medicine
position in division: Oncology
sort order: 1
type: Position
HR job title: Associate Professor of Medicine
position in organization: Dana-Farber Cancer Institute

Victor J. Aresty Professor of Medicine
is primary position: true
position in department: Medicine
position in division: DF Melanoma
sort order: 1
type: Position
HR job title: Victor J. Aresty Professor of Medicine
position in organization: Beth Israel Deaconess Medical Center

DF Melanoma
type: Division
type: Organization

Authorship 727422
type: Authorship
author rank in publication: 3
linked author: Van Allen, Eliezer
linked information resource: Activating mTOR mutations in a patient with an extraordinary response on a phase I trial of everolimus and pazopanib.

Authorship 727192
type: Authorship
author rank in publication: 21
linked author: Van Allen, Eliezer
linked information resource: Whole-exome sequencing of circulating tumor cells provides a window into metastatic prostate cancer.

Activating mTOR mutations in a patient with an extraordinary response on a phase I trial of everolimus and pazopanib.
PubMed Identifier: 24625776
author list: Wagle N, Grabiner BC, Van Allen EM, Hodis E, Jacobus S, Supko JG, Stewart M, Choueiri TK, Gandhi L, Cleary JM, Elfiky AA, Taplin ME, Stack EC, Signoretti S, Loda M, Shapiro GI, Sabatini DM, Lander ES, Gabriel SB, Kantoff PW, Garraway LA, Rosenberg JE
published in: Cancer discovery
information resource reference: Activating mTOR mutations in a patient with an extraordinary response on a phase I trial of everolimus and pazopanib. Cancer Discov. 2014 May; 4(5):546-53.
journal title abbreviation: Cancer Discov
publication date: 2014-03-13T00:00:00
year: 2014
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 731274
type: Authorship
author rank in publication: 1
linked author: Van Allen, Eliezer
linked information resource: Whole-exome sequencing and clinical interpretation of formalin-fixed, paraffin-embedded tumor samples to guide precision cancer medicine.

Whole-exome sequencing and clinical interpretation of formalin-fixed, paraffin-embedded tumor samples to guide precision cancer medicine.
PubMed Identifier: 24836576
author list: Van Allen EM, Wagle N, Stojanov P, Perrin DL, Cibulskis K, Marlow S, Jane-Valbuena J, Friedrich DC, Kryukov G, Carter SL, McKenna A, Sivachenko A, Rosenberg M, Kiezun A, Voet D, Lawrence M, Lichtenstein LT, Gentry JG, Huang FW, Fostel J, Farlow D, Barbie D, Gandhi L, Lander ES, Gray SW, Joffe S, Janne P, Garber J, MacConaill L, Lindeman N, Rollins B, Kantoff P, Fisher SA, Gabriel S, Getz G, Garraway LA
published in: Nature medicine
information resource reference: Whole-exome sequencing and clinical interpretation of formalin-fixed, paraffin-embedded tumor samples to guide precision cancer medicine. Nat Med. 2014 Jun; 20(6):682-8.
journal title abbreviation: Nat Med
publication date: 2014-05-18T00:00:00
year: 2014
type: Academic Article
type: Article
type: Document
type: Information Resource

Fusion-driven oncogenic programs shape the immune landscape in translocation renal cell carcinoma.
PubMed Identifier: 40950046
author list: Konda P, Weiss CN, Cui Y, Matar S, Wang J, Nabil YL, Deodhar R, Li J, Horst J, Camp SY, Sheshdeh AB, Hecht JL, Einstein DJ, Rustagi Y, Nag A, Thorner AR, Zhang CZ, Van Allen EM, Signoretti S, Choueiri TK, Viswanathan SR
published in: bioRxiv : the preprint server for biology
information resource reference: Fusion-driven oncogenic programs shape the immune landscape in translocation renal cell carcinoma. bioRxiv. 2025 Sep 01.
journal title abbreviation: bioRxiv
publication date: 2025-09-01T00:00:00
year: 2025
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1771404
type: Authorship
author rank in publication: 27
linked author: Van Allen, Eliezer
linked information resource: Efficacy, safety, and predictive biomarkers of neoadjuvant nab-paclitaxel and pembrolizumab in hormone receptor-positive breast cancer: A randomized pilot trial.

Authorship 1778684
type: Authorship
author rank in publication: 16
linked author: Van Allen, Eliezer
linked information resource: Implementing a context-augmented large language model to guide precision cancer medicine.

Authorship 1783899
type: Authorship
author rank in publication: 18
linked author: Van Allen, Eliezer
linked information resource: Fusion-driven oncogenic programs shape the immune landscape in translocation renal cell carcinoma.

Authorship 1784596
type: Authorship
author rank in publication: 18
linked author: Van Allen, Eliezer
linked information resource: Conserved Neuronal-like and Secretory Programs Define the Spatial Architecture of Gastroenteropancreatic Neuroendocrine Tumors.

Authorship 1783347
type: Authorship
author rank in publication: 16
linked author: Van Allen, Eliezer
linked information resource: Disruption of Microhomology-mediated End-joining in Ewing Sarcoma.

Authorship 1794552
type: Authorship
author rank in publication: 9
linked author: Van Allen, Eliezer
linked information resource: Mechanisms of tumor persistence in metastatic melanoma following successful immunotherapy.

Authorship 1808942
type: Authorship
author rank in publication: 21
linked author: Van Allen, Eliezer
linked information resource: Optimizing participant and community engagement in cancer genomic sequencing research.

Authorship 1814970
type: Authorship
author rank in publication: 29
linked author: Van Allen, Eliezer
linked information resource: Single-cell epigenetic profiling reveals a tumor-intrinsic interferon response program in ccRCC tied to poor prognosis and BAP1 loss.

Authorship 1815745
type: Authorship
author rank in publication: 22
linked author: Van Allen, Eliezer
linked information resource: Tamoxifen induces PI3K activation in uterine cancer.

Authorship 1816793
type: Authorship
author rank in publication: 25
linked author: Van Allen, Eliezer
linked information resource: Comparative Survival in Metastatic Hormone-sensitive Prostate Cancer by Volume of Disease and Timing of Metastasis: A Living Network Meta-analysis.

Authorship 1817281
type: Authorship
author rank in publication: 21
linked author: Van Allen, Eliezer
linked information resource: Cellular reprogramming during anti-PD-1 and chemotherapy treatment in early-stage primary hormone receptor-positive breast cancer.

Authorship 1817863
type: Authorship
author rank in publication: 10
linked author: Van Allen, Eliezer
linked information resource: Learning Patient Similarity from Genomics for Precision Oncology.

Authorship 1824432
type: Authorship
author rank in publication: 16
linked author: Van Allen, Eliezer
linked information resource: Relationship Among DNA Damage Response Gene Alterations, Molecular Subtypes, and Survival Outcomes in Patients With Metastatic Bladder Cancer Treated on CALGB 90601.

Authorship 1828555
type: Authorship
author rank in publication: 15
linked author: Van Allen, Eliezer
linked information resource: Spatially organized lymphocytic microenvironments in high grade primary prostate tumors.

Authorship 1829483
type: Authorship
author rank in publication: 5
linked author: Van Allen, Eliezer
linked information resource: Segregating DNA lesions point to high selective advantage of tumor initiating cells.

Authorship 1835560
type: Authorship
author rank in publication: 20
linked author: Van Allen, Eliezer
linked information resource: A context-augmented large language model for accurate precision oncology medicine recommendations.

Authorship 1844290
type: Authorship
author rank in publication: 17
linked author: Van Allen, Eliezer
linked information resource: Immune Spatial Organization Predicts Metastasis Risk in Aggressive Localized Prostate Cancer.

Authorship 1844481
type: Authorship
author rank in publication: 30
linked author: Van Allen, Eliezer
linked information resource: Tumor and immune reprogramming during immunotherapy in advanced renal cell carcinoma.

Authorship 1845616
type: Authorship
author rank in publication: 6
linked author: Van Allen, Eliezer
linked information resource: Dynamic single-cell systemic immune responses in immunotherapy-treated early-stage HR+ breast cancer patients.

Authorship 1850791
type: Authorship
author rank in publication: 14
linked author: Van Allen, Eliezer
linked information resource: Evaluation of single-cell RNA profiling technologies using FFPE, fresh, and frozen ccRCC tumor specimens.

Authorship 1850018
type: Authorship
author rank in publication: 8
linked author: Van Allen, Eliezer
linked information resource: Simulation and empirical evaluation of biologically-informed neural network performance.

Authorship 1849871
type: Authorship
author rank in publication: 4
linked author: Van Allen, Eliezer
linked information resource: Empirical Evaluation of Single-Cell Foundation Models for Predicting Cancer Outcomes.

Authorship 1851981
type: Authorship
author rank in publication: 28
linked author: Van Allen, Eliezer
linked information resource: Epigenetic dysregulation of metabolic programs mediates liposarcoma cell plasticity.

Tumor and immune reprogramming during immunotherapy in advanced renal cell carcinoma.
PubMed Identifier: 40494276
author list: Bi K, He MX, Bakouny Z, Kanodia A, Napolitano S, Wu J, Grimaldi G, Braun DA, Cuoco MS, Mayorga A, DelloStritto L, Bouchard G, Steinharter J, Tewari AK, Vokes NI, Shannon E, Sun M, Park J, Chang SL, McGregor BA, Haq R, Denize T, Signoretti S, Guerriero JL, Vigneau S, Rozenblatt-Rosen O, Rotem A, Regev A, Choueiri TK, Van Allen EM
published in: Cancer cell
information resource reference: Tumor and immune reprogramming during immunotherapy in advanced renal cell carcinoma. Cancer Cell. 2025 Jun 09; 43(6):1177-1179.
journal title abbreviation: Cancer Cell
publication date: 2025-06-09T00:00:00
year: 2025
type: Academic Article
type: Article
type: Document
type: Information Resource

Optimizing participant and community engagement in cancer genomic sequencing research.
PubMed Identifier: 40517303
author list: Crossnohere NL, Schuster ALR, Blair CK, Bland H, Carpten JD, Claus EB, Colditz GA, Diehl D, Ding L, Drake BF, Fields RC, George S, Janeway K, Kim H, Lenz HJ, Mack JW, Ricker C, Stern MC, Sussman A, Trent J, Van Allen E, Verhaak R, Willman C, Bridges JFP, Mishra SI, Kwan BM
published in: Genetics in medicine : official journal of the American College of Medical Genetics
information resource reference: Optimizing participant and community engagement in cancer genomic sequencing research. Genet Med. 2025 Sep; 27(9):101483.
journal title abbreviation: Genet Med
publication date: 2025-06-11T00:00:00
year: 2025
type: Academic Article
type: Article
type: Document
type: Information Resource

Tamoxifen induces PI3K activation in uterine cancer.
PubMed Identifier: 40846762
author list: Kübler K, Nardone A, Anand S, Gurevich D, Gao J, Droog M, Hermida-Prado F, Akhshi T, Feiglin A, Feit AS, Cohen Feit G, Dackus G, Pun M, Kuang Y, Cha J, Miller M, Gregoricchio S, Lanfermeijer M, Cornelissen S, Gibson WJ, Paweletz CP, Van Allen EM, van Leeuwen FE, Nederlof PM, Nguyen QD, Mourits MJE, Radovich M, Leshchiner I, Stewart C, Matulonis UA, Zwart W, Maruvka YE, Getz G, Jeselsohn R
published in: Nature genetics
information resource reference: Tamoxifen induces PI3K activation in uterine cancer. Nat Genet. 2025 Sep; 57(9):2192-2202.
journal title abbreviation: Nat Genet
publication date: 2025-08-22T00:00:00
year: 2025
type: Academic Article
type: Article
type: Document
type: Information Resource

Spatially organized lymphocytic microenvironments in high grade primary prostate tumors.
PubMed Identifier: 41000797
author list: Amiryousefi A, Wala J, Lin JR, Labadie BW, Atmakuri A, Maliga Z, Toye E, Chaudagar K, Torcasso MS, Coy S, Fanelli GN, Kobs B, Socciarelli F, Gagne A, Van Allen EM, Patnaik A, Sorger P
published in: bioRxiv : the preprint server for biology
information resource reference: Spatially organized lymphocytic microenvironments in high grade primary prostate tumors. bioRxiv. 2025 Sep 21.
journal title abbreviation: bioRxiv
publication date: 2025-09-21T00:00:00
year: 2025
type: Academic Article
type: Article
type: Document
type: Information Resource

Learning Patient Similarity from Genomics for Precision Oncology.
PubMed Identifier: 41445600
author list: Shady M, Reardon B, Jiang S, Pimenta E, O'Meara T, Park J, Kehl KL, Elmarakeby HA, Sunyaev SR, Van Allen EM
published in: medRxiv : the preprint server for health sciences
information resource reference: Learning Patient Similarity from Genomics for Precision Oncology. medRxiv. 2025 Dec 18.
journal title abbreviation: medRxiv
publication date: 2025-12-18T00:00:00
year: 2025
type: Academic Article
type: Article
type: Document
type: Information Resource

Mechanisms of tumor persistence in metastatic melanoma following successful immunotherapy.
PubMed Identifier: 41473281
author list: Shi Y, Maliga Z, Vallius T, Pant SM, Pelletier R, Kobs B, Priyanka S, He Y, Van Allen E, Santagata S, Ott P, Lian CG, Buchbinder EI, Liu D, Sorger PK
published in: bioRxiv : the preprint server for biology
information resource reference: Mechanisms of tumor persistence in metastatic melanoma following successful immunotherapy. bioRxiv. 2025 Dec 15.
journal title abbreviation: bioRxiv
publication date: 2025-12-15T00:00:00
year: 2025
type: Academic Article
type: Article
type: Document
type: Information Resource

Epigenetic dysregulation of metabolic programs mediates liposarcoma cell plasticity.
PubMed Identifier: 41564157
author list: Pimenta EM, Garza AE, Camp SY, Park J, Hoffman SE, Valderrábano L, Fu J, Bi K, Carson MT, Karam J, Titchen BM, Medjahed S, Khandekar MJ, Shannon E, Kang YJ, Coy S, Lin JR, Nag A, Thorner AR, Gibson WJ, Santagata S, Raut CP, Hornick JL, Merriam P, Solimini NL, George S, Demetri GD, Van Allen EM
published in: Science translational medicine
information resource reference: Epigenetic dysregulation of metabolic programs mediates liposarcoma cell plasticity. Sci Transl Med. 2026 Jan 21; 18(833):eadw4689.
journal title abbreviation: Sci Transl Med
publication date: 2026-01-21T00:00:00
year: 2026
type: Academic Article
type: Article
type: Document
type: Information Resource

Single-cell epigenetic profiling reveals a tumor-intrinsic interferon response program in ccRCC tied to poor prognosis and BAP1 loss.
PubMed Identifier: 41719400
author list: Camp SY, He MX, Cuoco MS, Garza AE, Xirenayi S, Bakouny Z, Saad E, El Masri J, Pimenta E, Meli K, Labaki C, Titchen BM, Kang YJ, Horst J, Trowbridge R, Shannon E, Helvie K, Thorner AR, Vigneau S, Mayorga A, Kodali J, Lachmayr H, Bemus M, Chen P, Deng H, Park J, Choueiri TK, Bi K, Van Allen EM
published in: Science advances
information resource reference: Single-cell epigenetic profiling reveals a tumor-intrinsic interferon response program in ccRCC tied to poor prognosis and BAP1 loss. Sci Adv. 2026 Feb 20; 12(8):eadv5457.
journal title abbreviation: Sci Adv
publication date: 2026-02-20T00:00:00
year: 2026
type: Academic Article
type: Article
type: Document
type: Information Resource

A context-augmented large language model for accurate precision oncology medicine recommendations.
PubMed Identifier: 41544626
author list: Jun H, Tanaka Y, Johri S, Camp SY, Bao EL, Carvalho FLF, Gui DY, Jordan AC, Labaki C, Martin SD, Nagy M, O'Meara TA, Pappa T, Pimenta EM, Saad E, Yang DD, Gillani R, Tewari AK, Reardon B, Van Allen E
published in: Cancer cell
information resource reference: A context-augmented large language model for accurate precision oncology medicine recommendations. Cancer Cell. 2026 Mar 09; 44(3):676-685.e4.
journal title abbreviation: Cancer Cell
publication date: 2026-01-15T00:00:00
year: 2026
type: Academic Article
type: Article
type: Document
type: Information Resource

Immune Spatial Organization Predicts Metastasis Risk in Aggressive Localized Prostate Cancer.
PubMed Identifier: 40475504
author list: Yang DD, Abdelnaser A, Wala J, Haas AJ, Barney AA, Saad E, Crowdis JP, Ricker CA, Park J, King MT, Nguyen PL, Choueiri TK, Tewari AK, Salari K, Taplin ME, Wu CL, Van Allen EM
published in: bioRxiv : the preprint server for biology
information resource reference: Immune Spatial Organization Predicts Metastasis Risk in Aggressive Localized Prostate Cancer. bioRxiv. 2025 May 19.
journal title abbreviation: bioRxiv
publication date: 2025-05-19T00:00:00
year: 2025
type: Academic Article
type: Article
type: Document
type: Information Resource

Dynamic single-cell systemic immune responses in immunotherapy-treated early-stage HR+ breast cancer patients.
PubMed Identifier: 40610460
author list: Sun X, Axelrod ML, Waks AG, Fu J, DiLullo M, Van Allen EM, Tolaney SM, Mittendorf EA, Xu Y, Balko JM
published in: NPJ breast cancer
information resource reference: Dynamic single-cell systemic immune responses in immunotherapy-treated early-stage HR+ breast cancer patients. NPJ Breast Cancer. 2025 Jul 03; 11(1):65.
journal title abbreviation: NPJ Breast Cancer
publication date: 2025-07-03T00:00:00
year: 2025
type: Academic Article
type: Article
type: Document
type: Information Resource

Relationship Among DNA Damage Response Gene Alterations, Molecular Subtypes, and Survival Outcomes in Patients With Metastatic Bladder Cancer Treated on CALGB 90601.
PubMed Identifier: 40591902
author list: Iyer G, Choi W, Luo B, Carvalho F, Hanlon T, Reis H, Guercio BJ, Fong M, Mountain J, Feng M, Regazzi AM, McCart L, Wen Y, Al-Ahmadie H, Mouw KW, Van Allen EM, Bellmunt J, Dreicer R, Flaig TW, Halabi S, McConkey DJ, Rosenberg JE
published in: JCO precision oncology
information resource reference: Relationship Among DNA Damage Response Gene Alterations, Molecular Subtypes, and Survival Outcomes in Patients With Metastatic Bladder Cancer Treated on CALGB 90601. JCO Precis Oncol. 2025 Jul; 9:e2400938.
journal title abbreviation: JCO Precis Oncol
publication date: 2025-07-01T00:00:00
year: 2025
type: Academic Article
type: Article
type: Document
type: Information Resource

Segregating DNA lesions point to high selective advantage of tumor initiating cells.
PubMed Identifier: 41256703
author list: Seplyarskiy V, Shady M, Andrianova MA, Chapman MS, Van Allen EM, Sunyaev SR
published in: bioRxiv : the preprint server for biology
information resource reference: Segregating DNA lesions point to high selective advantage of tumor initiating cells. bioRxiv. 2025 Oct 04.
journal title abbreviation: bioRxiv
publication date: 2025-10-04T00:00:00
year: 2025
type: Academic Article
type: Article
type: Document
type: Information Resource

Simulation and empirical evaluation of biologically-informed neural network performance.
PubMed Identifier: 41292768
author list: Miller GA, Roman A, Glettig M, Elmarakeby HA, AlDubayan SH, Park J, Collins RL, Van Allen EM
published in: bioRxiv : the preprint server for biology
information resource reference: Simulation and empirical evaluation of biologically-informed neural network performance. bioRxiv. 2025 Nov 14.
journal title abbreviation: bioRxiv
publication date: 2025-11-14T00:00:00
year: 2025
type: Academic Article
type: Article
type: Document
type: Information Resource

Evaluation of single-cell RNA profiling technologies using FFPE, fresh, and frozen ccRCC tumor specimens.
PubMed Identifier: 41394662
author list: Xirenayi S, Camp SY, Garza AE, Rustagi Y, Pimenta E, Shannon E, Nag A, Betherman A, Anselmo A, Trowbridge R, Thorner AR, Park J, Bi K, Van Allen EM
published in: bioRxiv : the preprint server for biology
information resource reference: Evaluation of single-cell RNA profiling technologies using FFPE, fresh, and frozen ccRCC tumor specimens. bioRxiv. 2025 Nov 28.
journal title abbreviation: bioRxiv
publication date: 2025-11-28T00:00:00
year: 2025
type: Academic Article
type: Article
type: Document
type: Information Resource

Cellular reprogramming during anti-PD-1 and chemotherapy treatment in early-stage primary hormone receptor-positive breast cancer.
PubMed Identifier: 41315371
author list: Fu J, Waks AG, Pimenta E, Titchen B, Bi K, Camp S, Pappa T, Keenan T, Shannon E, Vigneau S, Bemus M, Nag A, Thorner AR, Park J, DiLullo M, Wrabel E, Jeselsohn R, Mittendorf EA, Abravanel DL, Tolaney SM, Van Allen EM
published in: Nature communications
information resource reference: Cellular reprogramming during anti-PD-1 and chemotherapy treatment in early-stage primary hormone receptor-positive breast cancer. Nat Commun. 2025 Nov 28; 16(1):10704.
journal title abbreviation: Nat Commun
publication date: 2025-11-28T00:00:00
year: 2025
type: Academic Article
type: Article
type: Document
type: Information Resource

Comparative Survival in Metastatic Hormone-sensitive Prostate Cancer by Volume of Disease and Timing of Metastasis: A Living Network Meta-analysis.
PubMed Identifier: 41193370
author list: Riaz IB, Ahmed Naqvi SA, Faisal KS, He H, Rubab Khakwani KZ, Childs DS, Orme JJ, Ravi P, Singh P, Hussain SA, Chi K, Agarwal N, Merseburger AS, Davis ID, Armstrong A, Hussain MH, Smith M, Attard G, Tombal B, Fizazi K, James N, Omlin A, Gillessen S, Murad MH, Van Allen EM, Sweeney CJ, Bryce AH
published in: European urology
information resource reference: Comparative Survival in Metastatic Hormone-sensitive Prostate Cancer by Volume of Disease and Timing of Metastasis: A Living Network Meta-analysis. Eur Urol. 2026 Jan; 89(1):31-44.
journal title abbreviation: Eur Urol
publication date: 2025-11-04T00:00:00
year: 2025
type: Academic Article
type: Article
type: Document
type: Information Resource

Empirical Evaluation of Single-Cell Foundation Models for Predicting Cancer Outcomes.
PubMed Identifier: 41279698
author list: Elmarakeby H, Roman A, Johri S, Van Allen EM
published in: bioRxiv : the preprint server for biology
information resource reference: Empirical Evaluation of Single-Cell Foundation Models for Predicting Cancer Outcomes. bioRxiv. 2025 Nov 03.
journal title abbreviation: bioRxiv
publication date: 2025-11-03T00:00:00
year: 2025
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 743873
type: Authorship
author rank in publication: 2
linked author: Van Allen, Eliezer
linked information resource: Assessing the clinical utility of cancer genomic and proteomic data across tumor types.

Assessing the clinical utility of cancer genomic and proteomic data across tumor types.
PubMed Identifier: 24952901
author list: Yuan Y, Van Allen EM, Omberg L, Wagle N, Amin-Mansour A, Sokolov A, Byers LA, Xu Y, Hess KR, Diao L, Han L, Huang X, Lawrence MS, Weinstein JN, Stuart JM, Mills GB, Garraway LA, Margolin AA, Getz G, Liang H
published in: Nature biotechnology
information resource reference: Assessing the clinical utility of cancer genomic and proteomic data across tumor types. Nat Biotechnol. 2014 Jul; 32(7):644-52.
journal title abbreviation: Nat Biotechnol
publication date: 2014-06-22T00:00:00
year: 2014
type: Academic Article
type: Article
type: Document
type: Information Resource

Assistant Professor of Radiation Oncology
is primary position: true
position in department: Radiation Oncology
position in division: https://connects.catalyst.harvard.edu/Profiles/profile/1229413
sort order: 1
type: Position
HR job title: Assistant Professor of Radiation Oncology
position in organization: Dana-Farber Cancer Institute

Aldubayan, Saud
eCommons Login: SHA16
first name: Saud
last name: Aldubayan
full name: Saud H Aldubayan, M.B.,B.S.
has faculty rank: Other Faculty
photo: https://connects.catalyst.harvard.edu/Profiles/profile/Modules/CustomViewPersonGeneralInfo/PhotoHandler.ashx
Person ID: 129930
person in primary position: Research Associate in Medicine
type: Agent
type: Person
preferred title: Research Associate in Medicine

Authorship 745007
type: Authorship
author rank in publication: 1
linked author: Van Allen, Eliezer
linked information resource: Somatic ERCC2 mutations correlate with cisplatin sensitivity in muscle-invasive urothelial carcinoma.

Somatic ERCC2 mutations correlate with cisplatin sensitivity in muscle-invasive urothelial carcinoma.
PubMed Identifier: 25096233
author list: Van Allen EM, Mouw KW, Kim P, Iyer G, Wagle N, Al-Ahmadie H, Zhu C, Ostrovnaya I, Kryukov GV, O'Connor KW, Sfakianos J, Garcia-Grossman I, Kim J, Guancial EA, Bambury R, Bahl S, Gupta N, Farlow D, Qu A, Signoretti S, Barletta JA, Reuter V, Boehm J, Lawrence M, Getz G, Kantoff P, Bochner BH, Choueiri TK, Bajorin DF, Solit DB, Gabriel S, D'Andrea A, Garraway LA, Rosenberg JE
published in: Cancer discovery
information resource reference: Somatic ERCC2 mutations correlate with cisplatin sensitivity in muscle-invasive urothelial carcinoma. Cancer Discov. 2014 Oct; 4(10):1140-53.
journal title abbreviation: Cancer Discov
publication date: 2014-08-05T00:00:00
year: 2014
type: Academic Article
type: Article
type: Document
type: Information Resource

Liu, David
eCommons Login: DL197
first name: David
last name: Liu
full name: David Liu, M.D.
has faculty rank: Assistant Professor
photo: https://connects.catalyst.harvard.edu/Profiles/profile/Modules/CustomViewPersonGeneralInfo/PhotoHandler.ashx
Person ID: 131167
person in primary position: Assistant Professor of Medicine
type: Agent
type: Person
preferred title: Assistant Professor of Medicine

Authorship 762206
type: Authorship
author rank in publication: 3
linked author: Van Allen, Eliezer
linked information resource: Response and acquired resistance to everolimus in anaplastic thyroid cancer.

Response and acquired resistance to everolimus in anaplastic thyroid cancer.
PubMed Identifier: 25295501
author list: Wagle N, Grabiner BC, Van Allen EM, Amin-Mansour A, Taylor-Weiner A, Rosenberg M, Gray N, Barletta JA, Guo Y, Swanson SJ, Ruan DT, Hanna GJ, Haddad RI, Getz G, Kwiatkowski DJ, Carter SL, Sabatini DM, Jänne PA, Garraway LA, Lorch JH
published in: The New England journal of medicine
information resource reference: Response and acquired resistance to everolimus in anaplastic thyroid cancer. N Engl J Med. 2014 Oct 09; 371(15):1426-33.
journal title abbreviation: N Engl J Med
publication date: 2014-10-09T00:00:00
year: 2014
type: Academic Article
type: Article
type: Document
type: Information Resource

RNF43 is frequently mutated in colorectal and endometrial cancers.
PubMed Identifier: 25344691
author list: Giannakis M, Hodis E, Jasmine Mu X, Yamauchi M, Rosenbluh J, Cibulskis K, Saksena G, Lawrence MS, Qian ZR, Nishihara R, Van Allen EM, Hahn WC, Gabriel SB, Lander ES, Getz G, Ogino S, Fuchs CS, Garraway LA
published in: Nature genetics
information resource reference: RNF43 is frequently mutated in colorectal and endometrial cancers. Nat Genet. 2014 Dec; 46(12):1264-6.
journal title abbreviation: Nat Genet
publication date: 2014-10-26T00:00:00
year: 2014
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 771547
type: Authorship
author rank in publication: 11
linked author: Van Allen, Eliezer
linked information resource: RNF43 is frequently mutated in colorectal and endometrial cancers.

Authorship 776750
type: Authorship
author rank in publication: 4
linked author: Van Allen, Eliezer
linked information resource: Complementary genomic approaches highlight the PI3K/mTOR pathway as a common vulnerability in osteosarcoma.

Authorship 776751
type: Authorship
linked author: Van Allen, Eliezer
linked information resource: Kinome-wide functional screen identifies role of PLK1 in hormone-independent, ER-positive breast cancer.

Kinome-wide functional screen identifies role of PLK1 in hormone-independent, ER-positive breast cancer.
PubMed Identifier: 25480943
author list: Bhola NE, Jansen VM, Bafna S, Giltnane JM, Balko JM, Estrada MV, Meszoely I, Mayer I, Abramson V, Ye F, Sanders M, Dugger TC, Allen EV, Arteaga CL
published in: Cancer research
information resource reference: Kinome-wide functional screen identifies role of PLK1 in hormone-independent, ER-positive breast cancer. Cancer Res. 2015 Jan 15; 75(2):405-14.
journal title abbreviation: Cancer Res
publication date: 2014-12-05T00:00:00
year: 2014
type: Academic Article
type: Article
type: Document
type: Information Resource

Complementary genomic approaches highlight the PI3K/mTOR pathway as a common vulnerability in osteosarcoma.
PubMed Identifier: 25512523
author list: Perry JA, Kiezun A, Tonzi P, Van Allen EM, Carter SL, Baca SC, Cowley GS, Bhatt AS, Rheinbay E, Pedamallu CS, Helman E, Taylor-Weiner A, McKenna A, DeLuca DS, Lawrence MS, Ambrogio L, Sougnez C, Sivachenko A, Walensky LD, Wagle N, Mora J, de Torres C, Lavarino C, Dos Santos Aguiar S, Yunes JA, Brandalise SR, Mercado-Celis GE, Melendez-Zajgla J, Cárdenas-Cardós R, Velasco-Hidalgo L, Roberts CW, Garraway LA, Rodriguez-Galindo C, Gabriel SB, Lander ES, Golub TR, Orkin SH, Getz G, Janeway KA
published in: Proceedings of the National Academy of Sciences of the United States of America
information resource reference: Complementary genomic approaches highlight the PI3K/mTOR pathway as a common vulnerability in osteosarcoma. Proc Natl Acad Sci U S A. 2014 Dec 23; 111(51):E5564-73.
journal title abbreviation: Proc Natl Acad Sci U S A
publication date: 2014-12-15T00:00:00
year: 2014
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 492048
type: Authorship
author rank in publication: 1
linked author: Van Allen, Eliezer
linked information resource: Comments on the recent clinical guidance statement on HIV screening.

Authorship 512258
type: Authorship
author rank in publication: 1
linked author: Van Allen, Eliezer
linked information resource: Moving toward personalized medicine in castration-resistant prostate cancer.

A functional landscape of resistance to ALK inhibition in lung cancer.
PubMed Identifier: 25759024
author list: Wilson FH, Johannessen CM, Piccioni F, Tamayo P, Kim JW, Van Allen EM, Corsello SM, Capelletti M, Calles A, Butaney M, Sharifnia T, Gabriel SB, Mesirov JP, Hahn WC, Engelman JA, Meyerson M, Root DE, Jänne PA, Garraway LA
published in: Cancer cell
information resource reference: A functional landscape of resistance to ALK inhibition in lung cancer. Cancer Cell. 2015 Mar 09; 27(3):397-408.
journal title abbreviation: Cancer Cell
publication date: 2015-03-09T00:00:00
year: 2015
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 41350
type: Authorship
author rank in publication: 9
linked author: Van Allen, Eliezer
linked information resource: Exome sequencing identifies recurrent SPOP, FOXA1 and MED12 mutations in prostate cancer.

Gillani, Riaz
eCommons Login: RG189
first name: Riaz
last name: Gillani
full name: Riaz Gillani, M.D.
has faculty rank: Assistant Professor
Person ID: 138571
person in primary position: Assistant Professor of Pediatrics
type: Agent
type: Person
preferred title: Assistant Professor of Pediatrics

Authorship 789036
type: Authorship
author rank in publication: 3
linked author: Van Allen, Eliezer
linked information resource: Clinical Acquired Resistance to RAF Inhibitor Combinations in BRAF-Mutant Colorectal Cancer through MAPK Pathway Alterations.

Authorship 802754
type: Authorship
author rank in publication: 6
linked author: Van Allen, Eliezer
linked information resource: A functional landscape of resistance to ALK inhibition in lung cancer.

Authorship 791112
type: Authorship
author rank in publication: 2
linked author: Van Allen, Eliezer
linked information resource: Integrative clinical genomics of advanced prostate cancer.

Authorship 805616
type: Authorship
author rank in publication: 5
linked author: Van Allen, Eliezer
linked information resource: PLZF, a tumor suppressor genetically lost in metastatic castration-resistant prostate cancer, is a mediator of resistance to androgen deprivation therapy.

Authorship 788978
type: Authorship
author rank in publication: 10
linked author: Van Allen, Eliezer
linked information resource: Somatic Copy Number Abnormalities and Mutations in PI3K/AKT/mTOR Pathway Have Prognostic Significance for Overall Survival in Platinum Treated Locally Advanced or Metastatic Urothelial Tumors.

Integrative clinical genomics of advanced prostate cancer.
PubMed Identifier: 26000489
author list: Robinson D, Van Allen EM, Wu YM, Schultz N, Lonigro RJ, Mosquera JM, Montgomery B, Taplin ME, Pritchard CC, Attard G, Beltran H, Abida W, Bradley RK, Vinson J, Cao X, Vats P, Kunju LP, Hussain M, Feng FY, Tomlins SA, Cooney KA, Smith DC, Brennan C, Siddiqui J, Mehra R, Chen Y, Rathkopf DE, Morris MJ, Solomon SB, Durack JC, Reuter VE, Gopalan A, Gao J, Loda M, Lis RT, Bowden M, Balk SP, Gaviola G, Sougnez C, Gupta M, Yu EY, Mostaghel EA, Cheng HH, Mulcahy H, True LD, Plymate SR, Dvinge H, Ferraldeschi R, Flohr P, Miranda S, Zafeiriou Z, Tunariu N, Mateo J, Perez-Lopez R, Demichelis F, Robinson BD, Schiffman M, Nanus DM, Tagawa ST, Sigaras A, Eng KW, Elemento O, Sboner A, Heath EI, Scher HI, Pienta KJ, Kantoff P, de Bono JS, Rubin MA, Nelson PS, Garraway LA, Sawyers CL, Chinnaiyan AM
published in: Cell
information resource reference: Integrative clinical genomics of advanced prostate cancer. Cell. 2015 May 21; 161(5):1215-1228.
journal title abbreviation: Cell
publication date: 2015-05-21T00:00:00
year: 2015
type: Academic Article
type: Article
type: Document
type: Information Resource

Somatic Copy Number Abnormalities and Mutations in PI3K/AKT/mTOR Pathway Have Prognostic Significance for Overall Survival in Platinum Treated Locally Advanced or Metastatic Urothelial Tumors.
PubMed Identifier: 26039708
author list: Bellmunt J, Werner L, Leow JJ, Mullane SA, Fay AP, Riester M, Van Hummelen P, Taplin ME, Choueiri TK, Van Allen E, Rosenberg J
published in: PloS one
information resource reference: Somatic Copy Number Abnormalities and Mutations in PI3K/AKT/mTOR Pathway Have Prognostic Significance for Overall Survival in Platinum Treated Locally Advanced or Metastatic Urothelial Tumors. PLoS One. 2015; 10(6):e0124711.
journal title abbreviation: PLoS One
publication date: 2015-06-03T00:00:00
year: 2015
type: Academic Article
type: Article
type: Document
type: Information Resource

PLZF, a tumor suppressor genetically lost in metastatic castration-resistant prostate cancer, is a mediator of resistance to androgen deprivation therapy.
PubMed Identifier: 25808865
author list: Hsieh CL, Botta G, Gao S, Li T, Van Allen EM, Treacy DJ, Cai C, He HH, Sweeney CJ, Brown M, Balk SP, Nelson PS, Garraway LA, Kantoff PW
published in: Cancer research
information resource reference: PLZF, a tumor suppressor genetically lost in metastatic castration-resistant prostate cancer, is a mediator of resistance to androgen deprivation therapy. Cancer Res. 2015 May 15; 75(10):1944-8.
journal title abbreviation: Cancer Res
publication date: 2015-03-25T00:00:00
year: 2015
type: Academic Article
type: Article
type: Document
type: Information Resource

Clinical Acquired Resistance to RAF Inhibitor Combinations in BRAF-Mutant Colorectal Cancer through MAPK Pathway Alterations.
PubMed Identifier: 25673644
author list: Ahronian LG, Sennott EM, Van Allen EM, Wagle N, Kwak EL, Faris JE, Godfrey JT, Nishimura K, Lynch KD, Mermel CH, Lockerman EL, Kalsy A, Gurski JM, Bahl S, Anderka K, Green LM, Lennon NJ, Huynh TG, Mino-Kenudson M, Getz G, Dias-Santagata D, Iafrate AJ, Engelman JA, Garraway LA, Corcoran RB
published in: Cancer discovery
information resource reference: Clinical Acquired Resistance to RAF Inhibitor Combinations in BRAF-Mutant Colorectal Cancer through MAPK Pathway Alterations. Cancer Discov. 2015 Apr; 5(4):358-67.
journal title abbreviation: Cancer Discov
publication date: 2015-02-11T00:00:00
year: 2015
type: Academic Article
type: Article
type: Document
type: Information Resource

DFCI
type: Division
type: Organization

Authorship 813562
type: Authorship
author rank in publication: 1
linked author: Van Allen, Eliezer
linked information resource: https://connects.catalyst.harvard.edu/Profiles/profile/59796168

https://connects.catalyst.harvard.edu/Profiles/profile/59796168
PubMed Identifier: 25770487
author list: Van Allen EM, Garraway LA, Rosenberg JE
published in: European urology
information resource reference: Re: Floris H. Groenendijk, Jeroen de Jong, Elisabeth E. Fransen van de Putte, et al. ERBB2 Mutations Characterize a Subgroup of Muscle-invasive Bladder Cancers with Excellent Response to Neoadjuvant Chemotherapy. Eur Urol. In press. http://dx.doi.org/10.1016/j.eururo.2015.01.014. Eur Urol. 2015 Aug; 68(2):e31-2.
journal title abbreviation: Eur Urol
publication date: 2015-03-12T00:00:00
year: 2015
type: Academic Article
type: Article
type: Document
type: Information Resource
label: Re: Floris H. Groenendijk, Jeroen de Jong, Elisabeth E. Fransen van de Putte, et al. ERBB2 Mutations Characterize a Subgroup of Muscle-invasive Bladder Cancers with Excellent Response to Neoadjuvant Chemotherapy. Eur Urol. In press. http://dx.doi.org/10.1016/j.eururo.2015.01.014.

Authorship 817100
type: Authorship
author rank in publication: 1
linked author: Van Allen, Eliezer
linked information resource: Genomic Correlate of Exceptional Erlotinib Response in Head and Neck Squamous Cell Carcinoma.

Genomic Correlate of Exceptional Erlotinib Response in Head and Neck Squamous Cell Carcinoma.
PubMed Identifier: 26181029
author list: Van Allen EM, Lui VW, Egloff AM, Goetz EM, Li H, Johnson JT, Duvvuri U, Bauman JE, Stransky N, Zeng Y, Gilbert BR, Pendleton KP, Wang L, Chiosea S, Sougnez C, Wagle N, Zhang F, Du Y, Close D, Johnston PA, McKenna A, Carter SL, Golub TR, Getz G, Mills GB, Garraway LA, Grandis JR
published in: JAMA oncology
information resource reference: Genomic Correlate of Exceptional Erlotinib Response in Head and Neck Squamous Cell Carcinoma. JAMA Oncol. 2015 May; 1(2):238-44.
journal title abbreviation: JAMA Oncol
publication date: 2015-05-01T00:00:00
year: 2015
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 821104
type: Authorship
author rank in publication: 2
linked author: Van Allen, Eliezer
linked information resource: Next-generation sequencing to guide cancer therapy.

Next-generation sequencing to guide cancer therapy.
PubMed Identifier: 26221189
author list: Gagan J, Van Allen EM
published in: Genome medicine
information resource reference: Next-generation sequencing to guide cancer therapy. Genome Med. 2015; 7(1):80.
journal title abbreviation: Genome Med
publication date: 2015-07-29T00:00:00
year: 2015
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 822228
type: Authorship
author rank in publication: 1
linked author: Van Allen, Eliezer
linked information resource: Long-term Benefit of PD-L1 Blockade in Lung Cancer Associated with JAK3 Activation.

Long-term Benefit of PD-L1 Blockade in Lung Cancer Associated with JAK3 Activation.
PubMed Identifier: 26014096
author list: Van Allen EM, Golay HG, Liu Y, Koyama S, Wong K, Taylor-Weiner A, Giannakis M, Harden M, Rojas-Rudilla V, Chevalier A, Thai T, Lydon C, Mach S, Avila AG, Wong JA, Rabin AR, Helmkamp J, Sholl L, Carter SL, Oxnard G, Janne P, Getz G, Lindeman N, Hammerman PS, Garraway LA, Hodi FS, Rodig SJ, Dranoff G, Wong KK, Barbie DA
published in: Cancer immunology research
information resource reference: Long-term Benefit of PD-L1 Blockade in Lung Cancer Associated with JAK3 Activation. Cancer Immunol Res. 2015 Aug; 3(8):855-63.
journal title abbreviation: Cancer Immunol Res
publication date: 2015-05-26T00:00:00
year: 2015
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 834745
type: Authorship
author rank in publication: 5
linked author: Van Allen, Eliezer
linked information resource: Phase II study of tivantinib (ARQ 197) in patients with metastatic triple-negative breast cancer.

Authorship 835635
type: Authorship
author rank in publication: 5
linked author: Van Allen, Eliezer
linked information resource: Phase 2 trial of sunitinib and gemcitabine in patients with sarcomatoid and/or poor-risk metastatic renal cell carcinoma.

Phase 2 trial of sunitinib and gemcitabine in patients with sarcomatoid and/or poor-risk metastatic renal cell carcinoma.
PubMed Identifier: 26058385
author list: Michaelson MD, McKay RR, Werner L, Atkins MB, Van Allen EM, Olivier KM, Song J, Signoretti S, McDermott DF, Choueiri TK
published in: Cancer
information resource reference: Phase 2 trial of sunitinib and gemcitabine in patients with sarcomatoid and/or poor-risk metastatic renal cell carcinoma. Cancer. 2015 Oct 01; 121(19):3435-43.
journal title abbreviation: Cancer
publication date: 2015-06-08T00:00:00
year: 2015
type: Academic Article
type: Article
type: Document
type: Information Resource

Phase II study of tivantinib (ARQ 197) in patients with metastatic triple-negative breast cancer.
PubMed Identifier: 26123926
author list: Tolaney SM, Tan S, Guo H, Barry W, Van Allen E, Wagle N, Brock J, Larrabee K, Paweletz C, Ivanova E, Janne P, Overmoyer B, Wright JJ, Shapiro GI, Winer EP, Krop IE
published in: Investigational new drugs
information resource reference: Phase II study of tivantinib (ARQ 197) in patients with metastatic triple-negative breast cancer. Invest New Drugs. 2015 Oct; 33(5):1108-14.
journal title abbreviation: Invest New Drugs
publication date: 2015-07-01T00:00:00
year: 2015
type: Academic Article
type: Article
type: Document
type: Information Resource

Genomic Characterization of Brain Metastases Reveals Branched Evolution and Potential Therapeutic Targets.
PubMed Identifier: 26410082
author list: Brastianos PK, Carter SL, Santagata S, Cahill DP, Taylor-Weiner A, Jones RT, Van Allen EM, Lawrence MS, Horowitz PM, Cibulskis K, Ligon KL, Tabernero J, Seoane J, Martinez-Saez E, Curry WT, Dunn IF, Paek SH, Park SH, McKenna A, Chevalier A, Rosenberg M, Barker FG, Gill CM, Van Hummelen P, Thorner AR, Johnson BE, Hoang MP, Choueiri TK, Signoretti S, Sougnez C, Rabin MS, Lin NU, Winer EP, Stemmer-Rachamimov A, Meyerson M, Garraway L, Gabriel S, Lander ES, Beroukhim R, Batchelor TT, Baselga J, Louis DN, Getz G, Hahn WC
published in: Cancer discovery
information resource reference: Genomic Characterization of Brain Metastases Reveals Branched Evolution and Potential Therapeutic Targets. Cancer Discov. 2015 Nov; 5(11):1164-1177.
journal title abbreviation: Cancer Discov
publication date: 2015-09-26T00:00:00
year: 2015
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 839427
type: Authorship
author rank in publication: 1
linked author: Van Allen, Eliezer
linked information resource: Genomic correlates of response to CTLA-4 blockade in metastatic melanoma.

Genomic correlates of response to CTLA-4 blockade in metastatic melanoma.
PubMed Identifier: 26359337
author list: Van Allen EM, Miao D, Schilling B, Shukla SA, Blank C, Zimmer L, Sucker A, Hillen U, Foppen MHG, Goldinger SM, Utikal J, Hassel JC, Weide B, Kaehler KC, Loquai C, Mohr P, Gutzmer R, Dummer R, Gabriel S, Wu CJ, Schadendorf D, Garraway LA
published in: Science (New York, N.Y.)
information resource reference: Genomic correlates of response to CTLA-4 blockade in metastatic melanoma. Science. 2015 Oct 09; 350(6257):207-211.
journal title abbreviation: Science
publication date: 2015-09-10T00:00:00
year: 2015
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 843550
type: Authorship
author rank in publication: 7
linked author: Van Allen, Eliezer
linked information resource: Genomic Characterization of Brain Metastases Reveals Branched Evolution and Potential Therapeutic Targets.

Authorship 849117
type: Authorship
author rank in publication: 11
linked author: Van Allen, Eliezer
linked information resource: CSER and eMERGE: current and potential state of the display of genetic information in the electronic health record.

CSER and eMERGE: current and potential state of the display of genetic information in the electronic health record.
PubMed Identifier: 26142422
author list: Shirts BH, Salama JS, Aronson SJ, Chung WK, Gray SW, Hindorff LA, Jarvik GP, Plon SE, Stoffel EM, Tarczy-Hornoch PZ, Van Allen EM, Weck KE, Chute CG, Freimuth RR, Grundmeier RW, Hartzler AL, Li R, Peissig PL, Peterson JF, Rasmussen LV, Starren JB, Williams MS, Overby CL
published in: Journal of the American Medical Informatics Association : JAMIA
information resource reference: CSER and eMERGE: current and potential state of the display of genetic information in the electronic health record. J Am Med Inform Assoc. 2015 Nov; 22(6):1231-42.
journal title abbreviation: J Am Med Inform Assoc
publication date: 2015-07-03T00:00:00
year: 2015
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 56627
type: Authorship
author rank in publication: 1
linked author: Van Allen, Eliezer
linked information resource: Novel secondary hormonal therapy in advanced prostate cancer: an update.

Genomic predictors of response to CTLA4 blockade in metastatic melanoma
end date: 2015-08-30T00:00:00
start date: 2015-06-15T00:00:00
type: Mentoring - Completed Student Project
overview: Summer

Exome sequencing reveals recurrent germ line variants in patients with familial Waldenström macroglobulinemia.
PubMed Identifier: 26903547
author list: Roccaro AM, Sacco A, Shi J, Chiarini M, Perilla-Glen A, Manier S, Glavey S, Aljawai Y, Mishima Y, Kawano Y, Moschetta M, Correll M, Improgo MR, Brown JR, Imberti L, Rossi G, Castillo JJ, Treon SP, Freedman ML, Van Allen EM, Hide W, Hiller E, Rainville I, Ghobrial IM
published in: Blood
information resource reference: Exome sequencing reveals recurrent germ line variants in patients with familial Waldenström macroglobulinemia. Blood. 2016 05 26; 127(21):2598-606.
journal title abbreviation: Blood
publication date: 2016-02-22T00:00:00
year: 2016
type: Academic Article
type: Article
type: Document
type: Information Resource

Mutations in TSC1, TSC2, and MTOR Are Associated with Response to Rapalogs in Patients with Metastatic Renal Cell Carcinoma.
PubMed Identifier: 26831717
author list: Kwiatkowski DJ, Choueiri TK, Fay AP, Rini BI, Thorner AR, de Velasco G, Tyburczy ME, Hamieh L, Albiges L, Agarwal N, Ho TH, Song J, Pignon JC, Barrios PM, Michaelson MD, Van Allen E, Krajewski KM, Porta C, Pal S, Bellmunt J, McDermott DF, Heng DYC, Gray KP, Signoretti S
published in: Clinical cancer research : an official journal of the American Association for Cancer Research
information resource reference: Mutations in TSC1, TSC2, and MTOR Are Associated with Response to Rapalogs in Patients with Metastatic Renal Cell Carcinoma. Clin Cancer Res. 2016 05 15; 22(10):2445-2452.
journal title abbreviation: Clin Cancer Res
publication date: 2016-02-01T00:00:00
year: 2016
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 866761
type: Authorship
author rank in publication: 14
linked author: Van Allen, Eliezer
linked information resource: Divergent clonal evolution of castration-resistant neuroendocrine prostate cancer.

Divergent clonal evolution of castration-resistant neuroendocrine prostate cancer.
PubMed Identifier: 26855148
author list: Beltran H, Prandi D, Mosquera JM, Benelli M, Puca L, Cyrta J, Marotz C, Giannopoulou E, Chakravarthi BV, Varambally S, Tomlins SA, Nanus DM, Tagawa ST, Van Allen EM, Elemento O, Sboner A, Garraway LA, Rubin MA, Demichelis F
published in: Nature medicine
information resource reference: Divergent clonal evolution of castration-resistant neuroendocrine prostate cancer. Nat Med. 2016 Mar; 22(3):298-305.
journal title abbreviation: Nat Med
publication date: 2016-02-08T00:00:00
year: 2016
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 873059
type: Authorship
author rank in publication: 19
linked author: Van Allen, Eliezer
linked information resource: Clonal neoantigens elicit T cell immunoreactivity and sensitivity to immune checkpoint blockade.

Clonal neoantigens elicit T cell immunoreactivity and sensitivity to immune checkpoint blockade.
PubMed Identifier: 26940869
author list: McGranahan N, Furness AJ, Rosenthal R, Ramskov S, Lyngaa R, Saini SK, Jamal-Hanjani M, Wilson GA, Birkbak NJ, Hiley CT, Watkins TB, Shafi S, Murugaesu N, Mitter R, Akarca AU, Linares J, Marafioti T, Henry JY, Van Allen EM, Miao D, Schilling B, Schadendorf D, Garraway LA, Makarov V, Rizvi NA, Snyder A, Hellmann MD, Merghoub T, Wolchok JD, Shukla SA, Wu CJ, Peggs KS, Chan TA, Hadrup SR, Quezada SA, Swanton C
published in: Science (New York, N.Y.)
information resource reference: Clonal neoantigens elicit T cell immunoreactivity and sensitivity to immune checkpoint blockade. Science. 2016 Mar 25; 351(6280):1463-9.
journal title abbreviation: Science
publication date: 2016-03-03T00:00:00
year: 2016
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 875575
type: Authorship
author rank in publication: 2
linked author: Van Allen, Eliezer
linked information resource: Precision medicine for advanced prostate cancer.

Precision medicine for advanced prostate cancer.
PubMed Identifier: 26909474
author list: Mullane SA, Van Allen EM
published in: Current opinion in urology
information resource reference: Precision medicine for advanced prostate cancer. Curr Opin Urol. 2016 May; 26(3):231-9.
journal title abbreviation: Curr Opin Urol
publication date: 2016-05-01T00:00:00
year: 2016
type: Academic Article
type: Article
type: Document
type: Information Resource

Characterizing genomic alterations in cancer by complementary functional associations.
PubMed Identifier: 27088724
author list: Kim JW, Botvinnik OB, Abudayyeh O, Birger C, Rosenbluh J, Shrestha Y, Abazeed ME, Hammerman PS, DiCara D, Konieczkowski DJ, Johannessen CM, Liberzon A, Alizad-Rahvar AR, Alexe G, Aguirre A, Ghandi M, Greulich H, Vazquez F, Weir BA, Van Allen EM, Tsherniak A, Shao DD, Zack TI, Noble M, Getz G, Beroukhim R, Garraway LA, Ardakani M, Romualdi C, Sales G, Barbie DA, Boehm JS, Hahn WC, Mesirov JP, Tamayo P
published in: Nature biotechnology
information resource reference: Characterizing genomic alterations in cancer by complementary functional associations. Nat Biotechnol. 2016 05; 34(5):539-46.
journal title abbreviation: Nat Biotechnol
publication date: 2016-04-18T00:00:00
year: 2016
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 879142
type: Authorship
author rank in publication: 26
linked author: Van Allen, Eliezer
linked information resource: Dissecting the multicellular ecosystem of metastatic melanoma by single-cell RNA-seq.

Dissecting the multicellular ecosystem of metastatic melanoma by single-cell RNA-seq.
PubMed Identifier: 27124452
author list: Tirosh I, Izar B, Prakadan SM, Wadsworth MH, Treacy D, Trombetta JJ, Rotem A, Rodman C, Lian C, Murphy G, Fallahi-Sichani M, Dutton-Regester K, Lin JR, Cohen O, Shah P, Lu D, Genshaft AS, Hughes TK, Ziegler CG, Kazer SW, Gaillard A, Kolb KE, Villani AC, Johannessen CM, Andreev AY, Van Allen EM, Bertagnolli M, Sorger PK, Sullivan RJ, Flaherty KT, Frederick DT, Jané-Valbuena J, Yoon CH, Rozenblatt-Rosen O, Shalek AK, Regev A, Garraway LA
published in: Science (New York, N.Y.)
information resource reference: Dissecting the multicellular ecosystem of metastatic melanoma by single-cell RNA-seq. Science. 2016 Apr 08; 352(6282):189-96.
journal title abbreviation: Science
publication date: 2016-04-08T00:00:00
year: 2016
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 880544
type: Authorship
author rank in publication: 11
linked author: Van Allen, Eliezer
linked information resource: Genetic Effect of Chemotherapy Exposure in Children of Testicular Cancer Survivors.

Genetic Effect of Chemotherapy Exposure in Children of Testicular Cancer Survivors.
PubMed Identifier: 26631610
author list: Kryukov GV, Bielski CM, Samocha K, Fromer M, Seepo S, Gentry C, Neale B, Garraway LA, Sweeney CJ, Taplin ME, Van Allen EM
published in: Clinical cancer research : an official journal of the American Association for Cancer Research
information resource reference: Genetic Effect of Chemotherapy Exposure in Children of Testicular Cancer Survivors. Clin Cancer Res. 2016 05 01; 22(9):2183-9.
journal title abbreviation: Clin Cancer Res
publication date: 2015-12-02T00:00:00
year: 2015
type: Academic Article
type: Article
type: Document
type: Information Resource

Genomic Correlates of Immune-Cell Infiltrates in Colorectal Carcinoma.
PubMed Identifier: 27149842
author list: Giannakis M, Mu XJ, Shukla SA, Qian ZR, Cohen O, Nishihara R, Bahl S, Cao Y, Amin-Mansour A, Yamauchi M, Sukawa Y, Stewart C, Rosenberg M, Mima K, Inamura K, Nosho K, Nowak JA, Lawrence MS, Giovannucci EL, Chan AT, Ng K, Meyerhardt JA, Van Allen EM, Getz G, Gabriel SB, Lander ES, Wu CJ, Fuchs CS, Ogino S, Garraway LA
published in: Cell reports
information resource reference: Genomic Correlates of Immune-Cell Infiltrates in Colorectal Carcinoma. Cell Rep. 2016 Apr 26; 15(4):857-865.
journal title abbreviation: Cell Rep
publication date: 2016-04-14T00:00:00
year: 2016
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 881091
type: Authorship
author rank in publication: 16
linked author: Van Allen, Eliezer
linked information resource: Mutations in TSC1, TSC2, and MTOR Are Associated with Response to Rapalogs in Patients with Metastatic Renal Cell Carcinoma.

Authorship 881571
type: Authorship
author rank in publication: 20
linked author: Van Allen, Eliezer
linked information resource: Characterizing genomic alterations in cancer by complementary functional associations.

Authorship 883345
type: Authorship
author rank in publication: 20
linked author: Van Allen, Eliezer
linked information resource: Exome sequencing reveals recurrent germ line variants in patients with familial Waldenström macroglobulinemia.

Authorship 883256
type: Authorship
author rank in publication: 8
linked author: Van Allen, Eliezer
linked information resource: Somatic ERCC2 mutations are associated with a distinct genomic signature in urothelial tumors.

Somatic ERCC2 mutations are associated with a distinct genomic signature in urothelial tumors.
PubMed Identifier: 27111033
author list: Kim J, Mouw KW, Polak P, Braunstein LZ, Kamburov A, Kwiatkowski DJ, Rosenberg JE, Van Allen EM, D'Andrea A, Getz G
published in: Nature genetics
information resource reference: Somatic ERCC2 mutations are associated with a distinct genomic signature in urothelial tumors. Nat Genet. 2016 06; 48(6):600-606.
journal title abbreviation: Nat Genet
publication date: 2016-04-25T00:00:00
year: 2016
type: Academic Article
type: Article
type: Document
type: Information Resource

Pimenta, Erica
eCommons Login: EMP25
first name: Erica
last name: Pimenta
full name: Erica Maria Pimenta, M.D., Ph.D.
has faculty rank: Instructor
Person ID: 150429
person in primary position: Instructor in Medicine
type: Agent
type: Person
preferred title: Instructor in Medicine

Assistant Professor
sort order: 2
type: Faculty Rank

Associate Professor
sort order: 1
type: Faculty Rank

Full Professor
sort order: 0
type: Faculty Rank

Instructor
sort order: 4
type: Faculty Rank

Lecturer
sort order: 3
type: Faculty Rank

Other Faculty
sort order: 5
type: Faculty Rank

Authorship 891715
type: Authorship
author rank in publication: 4
linked author: Van Allen, Eliezer
linked information resource: Whole-Exome Sequencing in Two Extreme Phenotypes of Response to VEGF-Targeted Therapies in Patients With Metastatic Clear Cell Renal Cell Carcinoma.

Whole-Exome Sequencing in Two Extreme Phenotypes of Response to VEGF-Targeted Therapies in Patients With Metastatic Clear Cell Renal Cell Carcinoma.
PubMed Identifier: 27407122
author list: Fay AP, de Velasco G, Ho TH, Van Allen EM, Murray B, Albiges L, Signoretti S, Hakimi AA, Stanton ML, Bellmunt J, McDermott DF, Atkins MB, Garraway LA, Kwiatkowski DJ, Choueiri TK
published in: Journal of the National Comprehensive Cancer Network : JNCCN
information resource reference: Whole-Exome Sequencing in Two Extreme Phenotypes of Response to VEGF-Targeted Therapies in Patients With Metastatic Clear Cell Renal Cell Carcinoma. J Natl Compr Canc Netw. 2016 07; 14(7):820-4.
journal title abbreviation: J Natl Compr Canc Netw
publication date: 2016-07-01T00:00:00
year: 2016
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 894048
type: Authorship
author rank in publication: 21
linked author: Van Allen, Eliezer
linked information resource: The impact of tumor profiling approaches and genomic data strategies for cancer precision medicine.

Authorship 895082
type: Authorship
author rank in publication: 10
linked author: Van Allen, Eliezer
linked information resource: A phase 1 study of buparlisib and bevacizumab in patients with metastatic renal cell carcinoma progressing on vascular endothelial growth factor-targeted therapies.

A phase 1 study of buparlisib and bevacizumab in patients with metastatic renal cell carcinoma progressing on vascular endothelial growth factor-targeted therapies.
PubMed Identifier: 27198170
author list: McKay RR, De Velasco G, Werner L, Bellmunt J, Harshman L, Sweeney C, Rosenberg JE, Hirsch M, Signoretti S, Van Allen EM, Walsh M, Vaishampayan U, McDermott DF, Choueiri TK
published in: Cancer
information resource reference: A phase 1 study of buparlisib and bevacizumab in patients with metastatic renal cell carcinoma progressing on vascular endothelial growth factor-targeted therapies. Cancer. 2016 Aug 01; 122(15):2389-98.
journal title abbreviation: Cancer
publication date: 2016-05-19T00:00:00
year: 2016
type: Academic Article
type: Article
type: Document
type: Information Resource

The impact of tumor profiling approaches and genomic data strategies for cancer precision medicine.
PubMed Identifier: 27460824
author list: Garofalo A, Sholl L, Reardon B, Taylor-Weiner A, Amin-Mansour A, Miao D, Liu D, Oliver N, MacConaill L, Ducar M, Rojas-Rudilla V, Giannakis M, Ghazani A, Gray S, Janne P, Garber J, Joffe S, Lindeman N, Wagle N, Garraway LA, Van Allen EM
published in: Genome medicine
information resource reference: The impact of tumor profiling approaches and genomic data strategies for cancer precision medicine. Genome Med. 2016 07 26; 8(1):79.
journal title abbreviation: Genome Med
publication date: 2016-07-26T00:00:00
year: 2016
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 896887
type: Authorship
author rank in publication: 6
linked author: Van Allen, Eliezer
linked information resource: Clinical Validation of Chemotherapy Response Biomarker ERCC2 in Muscle-Invasive Urothelial Bladder Carcinoma.

Authorship 897254
type: Authorship
author rank in publication: 6
linked author: Van Allen, Eliezer
linked information resource: Characterization of Clinical Cases of Collecting Duct Carcinoma of the Kidney Assessed by Comprehensive Genomic Profiling.

Characterization of Clinical Cases of Collecting Duct Carcinoma of the Kidney Assessed by Comprehensive Genomic Profiling.
PubMed Identifier: 26149668
author list: Pal SK, Choueiri TK, Wang K, Khaira D, Karam JA, Van Allen E, Palma NA, Stein MN, Johnson A, Squillace R, Elvin JA, Chmielecki J, Yelensky R, Yakirevich E, Lipson D, Lin DI, Miller VA, Stephens PJ, Ali SM, Ross JS
published in: European urology
information resource reference: Characterization of Clinical Cases of Collecting Duct Carcinoma of the Kidney Assessed by Comprehensive Genomic Profiling. Eur Urol. 2016 09; 70(3):516-21.
journal title abbreviation: Eur Urol
publication date: 2015-07-03T00:00:00
year: 2015
type: Academic Article
type: Article
type: Document
type: Information Resource

Clinical Validation of Chemotherapy Response Biomarker ERCC2 in Muscle-Invasive Urothelial Bladder Carcinoma.
PubMed Identifier: 27310333
author list: Liu D, Plimack ER, Hoffman-Censits J, Garraway LA, Bellmunt J, Van Allen E, Rosenberg JE
published in: JAMA oncology
information resource reference: Clinical Validation of Chemotherapy Response Biomarker ERCC2 in Muscle-Invasive Urothelial Bladder Carcinoma. JAMA Oncol. 2016 Aug 01; 2(8):1094-6.
journal title abbreviation: JAMA Oncol
publication date: 2016-08-01T00:00:00
year: 2016
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 901368
type: Authorship
author rank in publication: 40
linked author: Van Allen, Eliezer
linked information resource: Inherited DNA-Repair Gene Mutations in Men with Metastatic Prostate Cancer.

Inherited DNA-Repair Gene Mutations in Men with Metastatic Prostate Cancer.
PubMed Identifier: 27433846
author list: Pritchard CC, Mateo J, Walsh MF, De Sarkar N, Abida W, Beltran H, Garofalo A, Gulati R, Carreira S, Eeles R, Elemento O, Rubin MA, Robinson D, Lonigro R, Hussain M, Chinnaiyan A, Vinson J, Filipenko J, Garraway L, Taplin ME, AlDubayan S, Han GC, Beightol M, Morrissey C, Nghiem B, Cheng HH, Montgomery B, Walsh T, Casadei S, Berger M, Zhang L, Zehir A, Vijai J, Scher HI, Sawyers C, Schultz N, Kantoff PW, Solit D, Robson M, Van Allen EM, Offit K, de Bono J, Nelson PS
published in: The New England journal of medicine
information resource reference: Inherited DNA-Repair Gene Mutations in Men with Metastatic Prostate Cancer. N Engl J Med. 2016 Aug 04; 375(5):443-53.
journal title abbreviation: N Engl J Med
publication date: 2016-07-06T00:00:00
year: 2016
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 908304
type: Authorship
author rank in publication: 2
linked author: Van Allen, Eliezer
linked information resource: Genomic determinants of cancer immunotherapy.

Genomic determinants of cancer immunotherapy.
PubMed Identifier: 27254251
author list: Miao D, Van Allen EM
published in: Current opinion in immunology
information resource reference: Genomic determinants of cancer immunotherapy. Curr Opin Immunol. 2016 08; 41:32-38.
journal title abbreviation: Curr Opin Immunol
publication date: 2016-05-30T00:00:00
year: 2016
type: Academic Article
type: Article
type: Document
type: Information Resource

Resistance to Emerging Androgen Deprivation Therapies in Prostate Cancer
end date: 2019-08-31
principal investigator name: VAN ALLEN, ELIEZER M
start date: 2014-09-10
type: Grant
sponsor award id: K08CA188615

The Use of Whole-Exome Sequencing to Guide the Care of Cancer Patients
end date: 2017-05-31
principal investigator name: JANNE, PASI A
start date: 2012-02-10
type: Grant
sponsor award id: U01HG006492

Principal Investigator
type: Researcher Role
researcher role of: Van Allen, Eliezer
contributes to: Resistance to Emerging Androgen Deprivation Therapies in Prostate Cancer

Authorship 917566
type: Authorship
author rank in publication: 14
linked author: Van Allen, Eliezer
linked information resource: Oncologists' and cancer patients' views on whole-exome sequencing and incidental findings: results from the CanSeq study.

Oncologists' and cancer patients' views on whole-exome sequencing and incidental findings: results from the CanSeq study.
PubMed Identifier: 26866579
author list: Gray SW, Park ER, Najita J, Martins Y, Traeger L, Bair E, Gagne J, Garber J, Jänne PA, Lindeman N, Lowenstein C, Oliver N, Sholl L, Van Allen EM, Wagle N, Wood S, Garraway L, Joffe S
published in: Genetics in medicine : official journal of the American College of Medical Genetics
information resource reference: Oncologists' and cancer patients' views on whole-exome sequencing and incidental findings: results from the CanSeq study. Genet Med. 2016 10; 18(10):1011-9.
journal title abbreviation: Genet Med
publication date: 2016-02-11T00:00:00
year: 2016
type: Academic Article
type: Article
type: Document
type: Information Resource

Genomic Correlates of Immune-Cell Infiltrates in Colorectal Carcinoma.
PubMed Identifier: 27760322
author list: Giannakis M, Mu XJ, Shukla SA, Qian ZR, Cohen O, Nishihara R, Bahl S, Cao Y, Amin-Mansour A, Yamauchi M, Sukawa Y, Stewart C, Rosenberg M, Mima K, Inamura K, Nosho K, Nowak JA, Lawrence MS, Giovannucci EL, Chan AT, Ng K, Meyerhardt JA, Van Allen EM, Getz G, Gabriel SB, Lander ES, Wu CJ, Fuchs CS, Ogino S, Garraway LA
published in: Cell reports
information resource reference: Genomic Correlates of Immune-Cell Infiltrates in Colorectal Carcinoma. Cell Rep. 2016 10 18; 17(4):1206.
journal title abbreviation: Cell Rep
publication date: 2016-10-18T00:00:00
year: 2016
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 926915
type: Authorship
author rank in publication: 23
linked author: Van Allen, Eliezer
linked information resource: Genomic Correlates of Immune-Cell Infiltrates in Colorectal Carcinoma.

Authorship 920214
type: Authorship
author rank in publication: 3
linked author: Van Allen, Eliezer
linked information resource: Genomic Approaches to Understanding Response and Resistance to Immunotherapy.

Authorship 926087
type: Authorship
author rank in publication: 23
linked author: Van Allen, Eliezer
linked information resource: Genomic Correlates of Immune-Cell Infiltrates in Colorectal Carcinoma.

Authorship 928627
type: Authorship
author rank in publication: 10
linked author: Van Allen, Eliezer
linked information resource: Tumor Mutational Load and Immune Parameters across Metastatic Renal Cell Carcinoma Risk Groups.

Genomic Approaches to Understanding Response and Resistance to Immunotherapy.
PubMed Identifier: 27698000
author list: Braun DA, Burke KP, Van Allen EM
published in: Clinical cancer research : an official journal of the American Association for Cancer Research
information resource reference: Genomic Approaches to Understanding Response and Resistance to Immunotherapy. Clin Cancer Res. 2016 Dec 01; 22(23):5642-5650.
journal title abbreviation: Clin Cancer Res
publication date: 2016-10-03T00:00:00
year: 2016
type: Academic Article
type: Article
type: Document
type: Information Resource

Tumor Mutational Load and Immune Parameters across Metastatic Renal Cell Carcinoma Risk Groups.
PubMed Identifier: 27538576
author list: de Velasco G, Miao D, Voss MH, Hakimi AA, Hsieh JJ, Tannir NM, Tamboli P, Appleman LJ, Rathmell WK, Van Allen EM, Choueiri TK
published in: Cancer immunology research
information resource reference: Tumor Mutational Load and Immune Parameters across Metastatic Renal Cell Carcinoma Risk Groups. Cancer Immunol Res. 2016 10; 4(10):820-822.
journal title abbreviation: Cancer Immunol Res
publication date: 2016-08-18T00:00:00
year: 2016
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 930034
type: Authorship
author rank in publication: 2
linked author: Van Allen, Eliezer
linked information resource: Delivering on the promise of precision cancer medicine.

Authorship 930692
type: Authorship
author rank in publication: 22
linked author: Van Allen, Eliezer
linked information resource: Genomic Heterogeneity and Exceptional Response to Dual Pathway Inhibition in Anaplastic Thyroid Cancer.

Authorship 931225
type: Authorship
author rank in publication: 12
linked author: Van Allen, Eliezer
linked information resource: Somatic cancer variant curation and harmonization through consensus minimum variant level data.

Authorship 933004
type: Authorship
author rank in publication: 18
linked author: Van Allen, Eliezer
linked information resource: Genomic Evolution after Chemoradiotherapy in Anal Squamous Cell Carcinoma.

Authorship 936403
type: Authorship
author rank in publication: 5
linked author: Van Allen, Eliezer
linked information resource: Tumor immune microenvironment characterization in clear cell renal cell carcinoma identifies prognostic and immunotherapeutically relevant messenger RNA signatures.

Somatic cancer variant curation and harmonization through consensus minimum variant level data.
PubMed Identifier: 27814769
author list: Ritter DI, Roychowdhury S, Roy A, Rao S, Landrum MJ, Sonkin D, Shekar M, Davis CF, Hart RK, Micheel C, Weaver M, Van Allen EM, Parsons DW, McLeod HL, Watson MS, Plon SE, Kulkarni S, Madhavan S
published in: Genome medicine
information resource reference: Somatic cancer variant curation and harmonization through consensus minimum variant level data. Genome Med. 2016 11 04; 8(1):117.
journal title abbreviation: Genome Med
publication date: 2016-11-04T00:00:00
year: 2016
type: Academic Article
type: Article
type: Document
type: Information Resource

Delivering on the promise of precision cancer medicine.
PubMed Identifier: 27782852
author list: Berger MF, Van Allen EM
published in: Genome medicine
information resource reference: Delivering on the promise of precision cancer medicine. Genome Med. 2016 10 25; 8(1):110.
journal title abbreviation: Genome Med
publication date: 2016-10-25T00:00:00
year: 2016
type: Academic Article
type: Article
type: Document
type: Information Resource

Tumor immune microenvironment characterization in clear cell renal cell carcinoma identifies prognostic and immunotherapeutically relevant messenger RNA signatures.
PubMed Identifier: 27855702
author list: Senbabaoglu Y, Gejman RS, Winer AG, Liu M, Van Allen EM, de Velasco G, Miao D, Ostrovnaya I, Drill E, Luna A, Weinhold N, Lee W, Manley BJ, Khalil DN, Kaffenberger SD, Chen Y, Danilova L, Voss MH, Coleman JA, Russo P, Reuter VE, Chan TA, Cheng EH, Scheinberg DA, Li MO, Choueiri TK, Hsieh JJ, Sander C, Hakimi AA
published in: Genome biology
information resource reference: Tumor immune microenvironment characterization in clear cell renal cell carcinoma identifies prognostic and immunotherapeutically relevant messenger RNA signatures. Genome Biol. 2016 11 17; 17(1):231.
journal title abbreviation: Genome Biol
publication date: 2016-11-17T00:00:00
year: 2016
type: Academic Article
type: Article
type: Document
type: Information Resource

A comparative assessment of clinical whole exome and transcriptome profiling across sequencing centers: implications for precision cancer medicine.
PubMed Identifier: 27167109
author list: Van Allen EM, Robinson D, Morrissey C, Pritchard C, Imamovic A, Carter S, Rosenberg M, McKenna A, Wu YM, Cao X, Chinnaiyan A, Garraway L, Nelson PS
published in: Oncotarget
information resource reference: A comparative assessment of clinical whole exome and transcriptome profiling across sequencing centers: implications for precision cancer medicine. Oncotarget. 2016 Aug 16; 7(33):52888-52899.
journal title abbreviation: Oncotarget
publication date: 2016-08-16T00:00:00
year: 2016
type: Academic Article
type: Article
type: Document
type: Information Resource

Genomic Evolution after Chemoradiotherapy in Anal Squamous Cell Carcinoma.
PubMed Identifier: 27852700
author list: Mouw KW, Cleary JM, Reardon B, Pike J, Braunstein LZ, Kim J, Amin-Mansour A, Miao D, Damish A, Chin J, Ott PA, Fuchs CS, Martin NE, Getz G, Carter S, Mamon HJ, Hornick JL, Van Allen EM, D'Andrea AD
published in: Clinical cancer research : an official journal of the American Association for Cancer Research
information resource reference: Genomic Evolution after Chemoradiotherapy in Anal Squamous Cell Carcinoma. Clin Cancer Res. 2017 Jun 15; 23(12):3214-3222.
journal title abbreviation: Clin Cancer Res
publication date: 2016-11-16T00:00:00
year: 2016
type: Academic Article
type: Article
type: Document
type: Information Resource

Genomic Heterogeneity and Exceptional Response to Dual Pathway Inhibition in Anaplastic Thyroid Cancer.
PubMed Identifier: 27797976
author list: Gibson WJ, Ruan DT, Paulson VA, Barletta JA, Hanna GJ, Kraft S, Calles A, Nehs MA, Moore FD, Taylor-Weiner A, Wala JA, Zack TI, Lee TC, Fennessy FM, Alexander EK, Thomas T, Janne PA, Garraway LA, Carter SL, Beroukhim R, Lorch JH, Van Allen EM
published in: Clinical cancer research : an official journal of the American Association for Cancer Research
information resource reference: Genomic Heterogeneity and Exceptional Response to Dual Pathway Inhibition in Anaplastic Thyroid Cancer. Clin Cancer Res. 2017 May 01; 23(9):2367-2373.
journal title abbreviation: Clin Cancer Res
publication date: 2016-10-17T00:00:00
year: 2016
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 941291
type: Authorship
author rank in publication: 7
linked author: Van Allen, Eliezer
linked information resource: Somatic Mutations and Neoepitope Homology in Melanomas Treated with CTLA-4 Blockade.

Somatic Mutations and Neoepitope Homology in Melanomas Treated with CTLA-4 Blockade.
PubMed Identifier: 27956380
author list: Nathanson T, Ahuja A, Rubinsteyn A, Aksoy BA, Hellmann MD, Miao D, Van Allen E, Merghoub T, Wolchok JD, Snyder A, Hammerbacher J
published in: Cancer immunology research
information resource reference: Somatic Mutations and Neoepitope Homology in Melanomas Treated with CTLA-4 Blockade. Cancer Immunol Res. 2017 01; 5(1):84-91.
journal title abbreviation: Cancer Immunol Res
publication date: 2016-12-12T00:00:00
year: 2016
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 945721
type: Authorship
author rank in publication: 1
linked author: Van Allen, Eliezer
linked information resource: A comparative assessment of clinical whole exome and transcriptome profiling across sequencing centers: implications for precision cancer medicine.

Authorship 945163
type: Authorship
author rank in publication: 33
linked author: Van Allen, Eliezer
linked information resource: Summary and Recommendations from the National Cancer Institute's Clinical Trials Planning Meeting on Novel Therapeutics for Non-Muscle Invasive Bladder Cancer.

Summary and Recommendations from the National Cancer Institute's Clinical Trials Planning Meeting on Novel Therapeutics for Non-Muscle Invasive Bladder Cancer.
PubMed Identifier: 27376138
author list: Lerner SP, Bajorin DF, Dinney CP, Efstathiou JA, Groshen S, Hahn NM, Hansel D, Kwiatkowski D, O'Donnell M, Rosenberg J, Svatek R, Abrams JS, Al-Ahmadie H, Apolo AB, Bellmunt J, Callahan M, Cha EK, Drake C, Jarow J, Kamat A, Kim W, Knowles M, Mann B, Marchionni L, McConkey D, McShane L, Ramirez N, Sharabi A, Sharpe AH, Solit D, Tangen CM, Amiri AT, Van Allen E, West PJ, Witjes JA, Quale DZ
published in: Bladder cancer (Amsterdam, Netherlands)
information resource reference: Summary and Recommendations from the National Cancer Institute's Clinical Trials Planning Meeting on Novel Therapeutics for Non-Muscle Invasive Bladder Cancer. Bladder Cancer. 2016 Apr 27; 2(2):165-202.
journal title abbreviation: Bladder Cancer
publication date: 2016-04-27T00:00:00
year: 2016
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 947625
type: Authorship
author rank in publication: 20
linked author: Van Allen, Eliezer
linked information resource: Genomic evolution and chemoresistance in germ-cell tumours.

Genomic evolution and chemoresistance in germ-cell tumours.
PubMed Identifier: 27905446
author list: Taylor-Weiner A, Zack T, O'Donnell E, Guerriero JL, Bernard B, Reddy A, Han GC, AlDubayan S, Amin-Mansour A, Schumacher SE, Litchfield K, Turnbull C, Gabriel S, Beroukhim R, Getz G, Carter SL, Hirsch MS, Letai A, Sweeney C, Van Allen EM
published in: Nature
information resource reference: Genomic evolution and chemoresistance in germ-cell tumours. Nature. 2016 11 30; 540(7631):114-118.
journal title abbreviation: Nature
publication date: 2016-11-30T00:00:00
year: 2016
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 951694
type: Authorship
author rank in publication: 38
linked author: Van Allen, Eliezer
linked information resource: Assigning clinical meaning to somatic and germ-line whole-exome sequencing data in a prospective cancer precision medicine study.

Assigning clinical meaning to somatic and germ-line whole-exome sequencing data in a prospective cancer precision medicine study.
PubMed Identifier: 28125075
author list: Ghazani AA, Oliver NM, St Pierre JP, Garofalo A, Rainville IR, Hiller E, Treacy DJ, Rojas-Rudilla V, Wood S, Bair E, Parello M, Huang F, Giannakis M, Wilson FH, Stover EH, Corsello SM, Nguyen T, Rana HQ, Church AJ, Lowenstein C, Cibulskis C, Amin-Mansour A, Heng J, Brais L, Santos A, Bauer P, Waldron A, Lo P, Gorman M, Lydon CA, Welch M, McNamara P, Gabriel S, Sholl LM, Lindeman NI, Garber JE, Joffe S, Van Allen EM, Gray SW, Ja Nne PA, Garraway LA, Wagle N
published in: Genetics in medicine : official journal of the American College of Medical Genetics
information resource reference: Assigning clinical meaning to somatic and germ-line whole-exome sequencing data in a prospective cancer precision medicine study. Genet Med. 2017 07; 19(7):787-795.
journal title abbreviation: Genet Med
publication date: 2017-01-26T00:00:00
year: 2017
type: Academic Article
type: Article
type: Document
type: Information Resource

https://connects.catalyst.harvard.edu/Profiles/profile/72396259
PubMed Identifier: 28159495
author list: Jay R, McKay RR, Werner L, Atkins MB, Van Allen EM, Olivier KM, Song J, Signoretti S, McDermott DF, Choueiri TK
published in: Urologic oncology
information resource reference: Phase 2 trial of sunitinib and gemcitabine in patients with sarcomatoid and/or poor-risk metastatic renal cell carcinoma. Michaelson MD, McKay RR, Werner L, Atkins MB, Van Allen EM, Olivier KM, Song J, Signoretti S, McDermott DF, Choueiri TK.Cancer. 2015 Oct 1;121(19):3435-43. [Epub 2015 Jun 8]. doi: 10.1002/cncr.29503. Urol Oncol. 2017 03; 35(3):117-118.
journal title abbreviation: Urol Oncol
publication date: 2017-02-01T00:00:00
year: 2017
type: Academic Article
type: Article
type: Document
type: Information Resource
label: Phase 2 trial of sunitinib and gemcitabine in patients with sarcomatoid and/or poor-risk metastatic renal cell carcinoma. Michaelson MD, McKay RR, Werner L, Atkins MB, Van Allen EM, Olivier KM, Song J, Signoretti S, McDermott DF, Choueiri TK.Cancer. 2015 Oct 1;121(19):3435-43. [Epub 2015 Jun 8]. doi: 10.1002/cncr.29503.

Authorship 957943
type: Authorship
author rank in publication: 16
linked author: Van Allen, Eliezer
linked information resource: Loss of PTEN Is Associated with Resistance to Anti-PD-1 Checkpoint Blockade Therapy in Metastatic Uterine Leiomyosarcoma.

Loss of PTEN Is Associated with Resistance to Anti-PD-1 Checkpoint Blockade Therapy in Metastatic Uterine Leiomyosarcoma.
PubMed Identifier: 28228279
author list: George S, Miao D, Demetri GD, Adeegbe D, Rodig SJ, Shukla S, Lipschitz M, Amin-Mansour A, Raut CP, Carter SL, Hammerman P, Freeman GJ, Wu CJ, Ott PA, Wong KK, Van Allen EM
published in: Immunity
information resource reference: Loss of PTEN Is Associated with Resistance to Anti-PD-1 Checkpoint Blockade Therapy in Metastatic Uterine Leiomyosarcoma. Immunity. 2017 02 21; 46(2):197-204.
journal title abbreviation: Immunity
publication date: 2017-02-21T00:00:00
year: 2017
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 969057
type: Authorship
author rank in publication: 5
linked author: Van Allen, Eliezer
linked information resource: Erratum to: Tumor immune microenvironment characterization in clear cell renal cell carcinoma identifies prognostic and immunotherapeutically relevant messenger RNA signatures.

Erratum to: Tumor immune microenvironment characterization in clear cell renal cell carcinoma identifies prognostic and immunotherapeutically relevant messenger RNA signatures.
PubMed Identifier: 28249590
author list: Senbabaoglu Y, Gejman RS, Winer AG, Liu M, Van Allen EM, de Velasco G, Miao D, Ostrovnaya I, Drill E, Luna A, Weinhold N, Lee W, Manley BJ, Khalil DN, Kaffenberger SD, Chen Y, Danilova L, Voss MH, Coleman JA, Russo P, Reuter VE, Chan TA, Cheng EH, Scheinberg DA, Li MO, Choueiri TK, Hsieh JJ, Sander C, Hakimi AA
published in: Genome biology
information resource reference: Erratum to: Tumor immune microenvironment characterization in clear cell renal cell carcinoma identifies prognostic and immunotherapeutically relevant messenger RNA signatures. Genome Biol. 2017 03 01; 18(1):46.
journal title abbreviation: Genome Biol
publication date: 2017-03-01T00:00:00
year: 2017
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 975229
type: Authorship
author rank in publication: 22
linked author: Van Allen, Eliezer
linked information resource: The Mutational Landscape of Circulating Tumor Cells in Multiple Myeloma.

The Mutational Landscape of Circulating Tumor Cells in Multiple Myeloma.
PubMed Identifier: 28380360
author list: Mishima Y, Paiva B, Shi J, Park J, Manier S, Takagi S, Massoud M, Perilla-Glen A, Aljawai Y, Huynh D, Roccaro AM, Sacco A, Capelletti M, Detappe A, Alignani D, Anderson KC, Munshi NC, Prosper F, Lohr JG, Ha G, Freeman SS, Van Allen EM, Adalsteinsson VA, Michor F, San Miguel JF, Ghobrial IM
published in: Cell reports
information resource reference: The Mutational Landscape of Circulating Tumor Cells in Multiple Myeloma. Cell Rep. 2017 04 04; 19(1):218-224.
journal title abbreviation: Cell Rep
publication date: 2017-04-04T00:00:00
year: 2017
type: Academic Article
type: Article
type: Document
type: Information Resource

Intron retention as a novel source of tumor neoantigens associated with response to checkpoint inhibitor therapy
end date: 2016-12-31T00:00:00
start date: 2016-02-01T00:00:00
type: Mentoring - Completed Student Project
overview: Summer

Authorship 981174
type: Authorship
author rank in publication: 26
linked author: Van Allen, Eliezer
linked information resource: Exome Sequencing of African-American Prostate Cancer Reveals Loss-of-Function ERF Mutations.

Exome Sequencing of African-American Prostate Cancer Reveals Loss-of-Function ERF Mutations.
PubMed Identifier: 28515055
author list: Huang FW, Mosquera JM, Garofalo A, Oh C, Baco M, Amin-Mansour A, Rabasha B, Bahl S, Mullane SA, Robinson BD, Aldubayan S, Khani F, Karir B, Kim E, Chimene-Weiss J, Hofree M, Romanel A, Osborne JR, Kim JW, Azabdaftari G, Woloszynska-Read A, Sfanos K, De Marzo AM, Demichelis F, Gabriel S, Van Allen EM, Mesirov J, Tamayo P, Rubin MA, Powell IJ, Garraway LA
published in: Cancer discovery
information resource reference: Exome Sequencing of African-American Prostate Cancer Reveals Loss-of-Function ERF Mutations. Cancer Discov. 2017 09; 7(9):973-983.
journal title abbreviation: Cancer Discov
publication date: 2017-05-17T00:00:00
year: 2017
type: Academic Article
type: Article
type: Document
type: Information Resource

Novel secondary hormonal therapy in advanced prostate cancer: an update.
PubMed Identifier: 19342958
author list: Van Allen EM, Ryan CJ
published in: Current opinion in urology
information resource reference: Novel secondary hormonal therapy in advanced prostate cancer: an update. Curr Opin Urol. 2009 May; 19(3):315-21.
journal title abbreviation: Curr Opin Urol
publication date: 2009-05-01T00:00:00
year: 2009
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 984959
type: Authorship
author rank in publication: 3
linked author: Van Allen, Eliezer
linked information resource: Toward Molecularly Driven Precision Medicine in Lung Adenocarcinoma.

Toward Molecularly Driven Precision Medicine in Lung Adenocarcinoma.
PubMed Identifier: 28576842
author list: Liu D, Vokes NI, Van Allen EM
published in: Cancer discovery
information resource reference: Toward Molecularly Driven Precision Medicine in Lung Adenocarcinoma. Cancer Discov. 2017 06; 7(6):555-557.
journal title abbreviation: Cancer Discov
publication date: 2017-06-01T00:00:00
year: 2017
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 988039
type: Authorship
author rank in publication: 19
linked author: Van Allen, Eliezer
linked information resource: Systematic genomic and translational efficiency studies of uveal melanoma.

Systematic genomic and translational efficiency studies of uveal melanoma.
PubMed Identifier: 28594900
author list: Johnson CP, Kim IK, Esmaeli B, Amin-Mansour A, Treacy DJ, Carter SL, Hodis E, Wagle N, Seepo S, Yu X, Lane AM, Gragoudas ES, Vazquez F, Nickerson E, Cibulskis K, McKenna A, Gabriel SB, Getz G, Van Allen EM, 't Hoen PAC, Garraway LA, Woodman SE
published in: PloS one
information resource reference: Systematic genomic and translational efficiency studies of uveal melanoma. PLoS One. 2017; 12(6):e0178189.
journal title abbreviation: PLoS One
publication date: 2017-06-08T00:00:00
year: 2017
type: Academic Article
type: Article
type: Document
type: Information Resource

Moving toward personalized medicine in castration-resistant prostate cancer.
PubMed Identifier: 23084525
author list: Van Allen EM, Pomerantz M
published in: The Urologic clinics of North America
information resource reference: Moving toward personalized medicine in castration-resistant prostate cancer. Urol Clin North Am. 2012 Nov; 39(4):483-90.
journal title abbreviation: Urol Clin North Am
publication date: 2012-08-27T00:00:00
year: 2012
type: Academic Article
type: Article
type: Document
type: Information Resource

44 Binney St
type: Address
address line 1: Dana-Farber Cancer Institute
address line 2: Dana 1120
address line 3: 44 Binney St
city: Boston
postal code: 02115
state or province: MA

Exome sequencing identifies recurrent SPOP, FOXA1 and MED12 mutations in prostate cancer.
PubMed Identifier: 22610119
author list: Barbieri CE, Baca SC, Lawrence MS, Demichelis F, Blattner M, Theurillat JP, White TA, Stojanov P, Van Allen E, Stransky N, Nickerson E, Chae SS, Boysen G, Auclair D, Onofrio RC, Park K, Kitabayashi N, MacDonald TY, Sheikh K, Vuong T, Guiducci C, Cibulskis K, Sivachenko A, Carter SL, Saksena G, Voet D, Hussain WM, Ramos AH, Winckler W, Redman MC, Ardlie K, Tewari AK, Mosquera JM, Rupp N, Wild PJ, Moch H, Morrissey C, Nelson PS, Kantoff PW, Gabriel SB, Golub TR, Meyerson M, Lander ES, Getz G, Rubin MA, Garraway LA
published in: Nature genetics
information resource reference: Exome sequencing identifies recurrent SPOP, FOXA1 and MED12 mutations in prostate cancer. Nat Genet. 2012 May 20; 44(6):685-9.
journal title abbreviation: Nat Genet
publication date: 2012-05-20T00:00:00
year: 2012
type: Academic Article
type: Article
type: Document
type: Information Resource

Comments on the recent clinical guidance statement on HIV screening.
PubMed Identifier: 19687498
author list: Van Allen EM, Kohlwes RJ
published in: Annals of internal medicine
information resource reference: Comments on the recent clinical guidance statement on HIV screening. Ann Intern Med. 2009 Aug 18; 151(4):286; author reply 287.
journal title abbreviation: Ann Intern Med
publication date: 2009-08-18T00:00:00
year: 2009
type: Academic Article
type: Article
type: Document
type: Information Resource

Off-label use of rituximab in a multipayer insurance system.
PubMed Identifier: 21731512
author list: Van Allen EM, Miyake T, Gunn N, Behler CM, Kohlwes J
published in: Journal of oncology practice
information resource reference: Off-label use of rituximab in a multipayer insurance system. J Oncol Pract. 2011 Mar; 7(2):76-9.
journal title abbreviation: J Oncol Pract
publication date: 2011-03-01T00:00:00
year: 2011
type: Academic Article
type: Article
type: Document
type: Information Resource

Decomposing Oncogenic Transcriptional Signatures to Generate Maps of Divergent Cellular States.
PubMed Identifier: 28837809
author list: Kim JW, Abudayyeh OO, Yeerna H, Yeang CH, Stewart M, Jenkins RW, Kitajima S, Konieczkowski DJ, Medetgul-Ernar K, Cavazos T, Mah C, Ting S, Van Allen EM, Cohen O, Mcdermott J, Damato E, Aguirre AJ, Liang J, Liberzon A, Alexe G, Doench J, Ghandi M, Vazquez F, Weir BA, Tsherniak A, Subramanian A, Meneses-Cime K, Park J, Clemons P, Garraway LA, Thomas D, Boehm JS, Barbie DA, Hahn WC, Mesirov JP, Tamayo P
published in: Cell systems
information resource reference: Decomposing Oncogenic Transcriptional Signatures to Generate Maps of Divergent Cellular States. Cell Syst. 2017 08 23; 5(2):105-118.e9.
journal title abbreviation: Cell Syst
publication date: 2017-08-23T00:00:00
year: 2017
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1000212
type: Authorship
author rank in publication: 13
linked author: Van Allen, Eliezer
linked information resource: Decomposing Oncogenic Transcriptional Signatures to Generate Maps of Divergent Cellular States.

Authorship 1000684
type: Authorship
author rank in publication: 15
linked author: Van Allen, Eliezer
linked information resource: In vivo CRISPR screening identifies Ptpn2 as a cancer immunotherapy target.

Authorship 1007130
type: Authorship
author rank in publication: 14
linked author: Van Allen, Eliezer
linked information resource: Genomic profiling of ER+ breast cancers after short-term estrogen suppression reveals alterations associated with endocrine resistance.

Authorship 1008081
type: Authorship
author rank in publication: 2
linked author: Van Allen, Eliezer
linked information resource: Integrative Clinical Genomics of Advanced Prostate Cancer.

Genomic profiling of ER+ breast cancers after short-term estrogen suppression reveals alterations associated with endocrine resistance.
PubMed Identifier: 28794284
author list: Giltnane JM, Hutchinson KE, Stricker TP, Formisano L, Young CD, Estrada MV, Nixon MJ, Du L, Sanchez V, Ericsson PG, Kuba MG, Sanders ME, Mu XJ, Van Allen EM, Wagle N, Mayer IA, Abramson V, G?mez H, Rizzo M, Toy W, Chandarlapaty S, Mayer EL, Christiansen J, Murphy D, Fitzgerald K, Wang K, Ross JS, Miller VA, Stephens PJ, Yelensky R, Garraway L, Shyr Y, Meszoely I, Balko JM, Arteaga CL
published in: Science translational medicine
information resource reference: Genomic profiling of ER+ breast cancers after short-term estrogen suppression reveals alterations associated with endocrine resistance. Sci Transl Med. 2017 Aug 09; 9(402).
journal title abbreviation: Sci Transl Med
publication date: 2017-08-09T00:00:00
year: 2017
type: Academic Article
type: Article
type: Document
type: Information Resource

Integrative Clinical Genomics of Advanced Prostate Cancer.
PubMed Identifier: 28843286
author list: Robinson D, Van Allen EM, Wu YM, Schultz N, Lonigro RJ, Mosquera JM, Montgomery B, Taplin ME, Pritchard CC, Attard G, Beltran H, Abida W, Bradley RK, Vinson J, Cao X, Vats P, Kunju LP, Hussain M, Feng FY, Tomlins SA, Cooney KA, Smith DC, Brennan C, Siddiqui J, Mehra R, Chen Y, Rathkopf DE, Morris MJ, Solomon SB, Durack JC, Reuter VE, Gopalan A, Gao J, Loda M, Lis RT, Bowden M, Balk SP, Gaviola G, Sougnez C, Gupta M, Yu EY, Mostaghel EA, Cheng HH, Mulcahy H, True LD, Plymate SR, Dvinge H, Ferraldeschi R, Flohr P, Miranda S, Zafeiriou Z, Tunariu N, Mateo J, Perez-Lopez R, Demichelis F, Robinson BD, Sboner A, Schiffman M, Nanus DM, Tagawa ST, Sigaras A, Eng KW, Elemento O, Sboner A, Heath EI, Scher HI, Pienta KJ, Kantoff P, de Bono JS, Rubin MA, Nelson PS, Garraway LA, Sawyers CL, Chinnaiyan AM
published in: Cell
information resource reference: Integrative Clinical Genomics of Advanced Prostate Cancer. Cell. 2015 Jul 16; 162(2):454.
journal title abbreviation: Cell
publication date: 2015-07-16T00:00:00
year: 2015
type: Academic Article
type: Article
type: Document
type: Information Resource

In vivo CRISPR screening identifies Ptpn2 as a cancer immunotherapy target.
PubMed Identifier: 28723893
author list: Manguso RT, Pope HW, Zimmer MD, Brown FD, Yates KB, Miller BC, Collins NB, Bi K, LaFleur MW, Juneja VR, Weiss SA, Lo J, Fisher DE, Miao D, Van Allen E, Root DE, Sharpe AH, Doench JG, Haining WN
published in: Nature
information resource reference: In vivo CRISPR screening identifies Ptpn2 as a cancer immunotherapy target. Nature. 2017 07 27; 547(7664):413-418.
journal title abbreviation: Nature
publication date: 2017-07-19T00:00:00
year: 2017
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1008913
type: Authorship
author rank in publication: 1
linked author: Van Allen, Eliezer
linked information resource: The Potential and Challenges of Expanded Germline Testing in Clinical Oncology.

The Potential and Challenges of Expanded Germline Testing in Clinical Oncology.
PubMed Identifier: 28873143
author list: Van Allen EM
published in: JAMA
information resource reference: The Potential and Challenges of Expanded Germline Testing in Clinical Oncology. JAMA. 2017 09 05; 318(9):801-803.
journal title abbreviation: JAMA
publication date: 2017-09-05T00:00:00
year: 2017
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1012063
type: Authorship
author rank in publication: 7
linked author: Van Allen, Eliezer
linked information resource: The fuzzy world of precision medicine: deliberations of a precision medicine tumor board.

The fuzzy world of precision medicine: deliberations of a precision medicine tumor board.
PubMed Identifier: 28757884
author list: McGraw SA, Garber J, Jänne PA, Lindeman N, Oliver N, Sholl LM, Van Allen EM, Wagle N, Garraway LA, Joffe S, Gray SW
published in: Personalized medicine
information resource reference: The fuzzy world of precision medicine: deliberations of a precision medicine tumor board. Per Med. 2017 Jan; 14(1):37-50.
journal title abbreviation: Per Med
publication date: 2016-12-15T00:00:00
year: 2016
type: Academic Article
type: Article
type: Document
type: Information Resource

Punctuated evolution of prostate cancer genomes.
PubMed Identifier: 23622249
author list: Baca SC, Prandi D, Lawrence MS, Mosquera JM, Romanel A, Drier Y, Park K, Kitabayashi N, MacDonald TY, Ghandi M, Van Allen E, Kryukov GV, Sboner A, Theurillat JP, Soong TD, Nickerson E, Auclair D, Tewari A, Beltran H, Onofrio RC, Boysen G, Guiducci C, Barbieri CE, Cibulskis K, Sivachenko A, Carter SL, Saksena G, Voet D, Ramos AH, Winckler W, Cipicchio M, Ardlie K, Kantoff PW, Berger MF, Gabriel SB, Golub TR, Meyerson M, Lander ES, Elemento O, Getz G, Demichelis F, Rubin MA, Garraway LA
published in: Cell
information resource reference: Punctuated evolution of prostate cancer genomes. Cell. 2013 Apr 25; 153(3):666-77.
journal title abbreviation: Cell
publication date: 2013-04-25T00:00:00
year: 2013
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1022987
type: Authorship
author rank in publication: 72
linked author: Van Allen, Eliezer
linked information resource: Ex Vivo Profiling of PD-1 Blockade Using Organotypic Tumor Spheroids.

Ex Vivo Profiling of PD-1 Blockade Using Organotypic Tumor Spheroids.
PubMed Identifier: 29101162
author list: Jenkins RW, Aref AR, Lizotte PH, Ivanova E, Stinson S, Zhou CW, Bowden M, Deng J, Liu H, Miao D, He MX, Walker W, Zhang G, Tian T, Cheng C, Wei Z, Palakurthi S, Bittinger M, Vitzthum H, Kim JW, Merlino A, Quinn M, Venkataramani C, Kaplan JA, Portell A, Gokhale PC, Phillips B, Smart A, Rotem A, Jones RE, Keogh L, Anguiano M, Stapleton L, Jia Z, Barzily-Rokni M, Cañadas I, Thai TC, Hammond MR, Vlahos R, Wang ES, Zhang H, Li S, Hanna GJ, Huang W, Hoang MP, Piris A, Eliane JP, Stemmer-Rachamimov AO, Cameron L, Su MJ, Shah P, Izar B, Thakuria M, LeBoeuf NR, Rabinowits G, Gunda V, Parangi S, Cleary JM, Miller BC, Kitajima S, Thummalapalli R, Miao B, Barbie TU, Sivathanu V, Wong J, Richards WG, Bueno R, Yoon CH, Miret J, Herlyn M, Garraway LA, Van Allen EM, Freeman GJ, Kirschmeier PT, Lorch JH, Ott PA, Hodi FS, Flaherty KT, Kamm RD, Boland GM, Wong KK, Dornan D, Paweletz CP, Barbie DA
published in: Cancer discovery
information resource reference: Ex Vivo Profiling of PD-1 Blockade Using Organotypic Tumor Spheroids. Cancer Discov. 2018 02; 8(2):196-215.
journal title abbreviation: Cancer Discov
publication date: 2017-11-03T00:00:00
year: 2017
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1025425
type: Authorship
author rank in publication: 45
linked author: Van Allen, Eliezer
linked information resource: Scalable whole-exome sequencing of cell-free DNA reveals high concordance with metastatic tumors.

Scalable whole-exome sequencing of cell-free DNA reveals high concordance with metastatic tumors.
PubMed Identifier: 29109393
author list: Adalsteinsson VA, Ha G, Freeman SS, Choudhury AD, Stover DG, Parsons HA, Gydush G, Reed SC, Rotem D, Rhoades J, Loginov D, Livitz D, Rosebrock D, Leshchiner I, Kim J, Stewart C, Rosenberg M, Francis JM, Zhang CZ, Cohen O, Oh C, Ding H, Polak P, Lloyd M, Mahmud S, Helvie K, Merrill MS, Santiago RA, O'Connor EP, Jeong SH, Leeson R, Barry RM, Kramkowski JF, Zhang Z, Polacek L, Lohr JG, Schleicher M, Lipscomb E, Saltzman A, Oliver NM, Marini L, Waks AG, Harshman LC, Tolaney SM, Van Allen EM, Winer EP, Lin NU, Nakabayashi M, Taplin ME, Johannessen CM, Garraway LA, Golub TR, Boehm JS, Wagle N, Getz G, Love JC, Meyerson M
published in: Nature communications
information resource reference: Scalable whole-exome sequencing of cell-free DNA reveals high concordance with metastatic tumors. Nat Commun. 2017 11 06; 8(1):1324.
journal title abbreviation: Nat Commun
publication date: 2017-11-06T00:00:00
year: 2017
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1029309
type: Authorship
author rank in publication: 2
linked author: Van Allen, Eliezer
linked information resource: Tumor Evolution: A Problem of Histocompatibility.

Tumor Evolution: A Problem of Histocompatibility.
PubMed Identifier: 29195070
author list: Vokes NI, Van Allen EM
published in: Cell
information resource reference: Tumor Evolution: A Problem of Histocompatibility. Cell. 2017 11 30; 171(6):1252-1253.
journal title abbreviation: Cell
publication date: 2017-11-30T00:00:00
year: 2017
type: Academic Article
type: Article
type: Document
type: Information Resource

A genome-scale RNA interference screen implicates NF1 loss in resistance to RAF inhibition.
PubMed Identifier: 23288408
author list: Whittaker SR, Theurillat JP, Van Allen E, Wagle N, Hsiao J, Cowley GS, Schadendorf D, Root DE, Garraway LA
published in: Cancer discovery
information resource reference: A genome-scale RNA interference screen implicates NF1 loss in resistance to RAF inhibition. Cancer Discov. 2013 Mar; 3(3):350-62.
journal title abbreviation: Cancer Discov
publication date: 2013-01-03T00:00:00
year: 2013
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1031654
type: Authorship
author rank in publication: 25
linked author: Van Allen, Eliezer
linked information resource: Mutational patterns in chemotherapy resistant muscle-invasive bladder cancer.

Mutational patterns in chemotherapy resistant muscle-invasive bladder cancer.
PubMed Identifier: 29259186
author list: Liu D, Abbosh P, Keliher D, Reardon B, Miao D, Mouw K, Weiner-Taylor A, Wankowicz S, Han G, Teo MY, Cipolla C, Kim J, Iyer G, Al-Ahmadie H, Dulaimi E, Chen DYT, Alpaugh RK, Hoffman-Censits J, Garraway LA, Getz G, Carter SL, Bellmunt J, Plimack ER, Rosenberg JE, Van Allen EM
published in: Nature communications
information resource reference: Mutational patterns in chemotherapy resistant muscle-invasive bladder cancer. Nat Commun. 2017 12 19; 8(1):2193.
journal title abbreviation: Nat Commun
publication date: 2017-12-19T00:00:00
year: 2017
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1036405
type: Authorship
author rank in publication: 26
linked author: Van Allen, Eliezer
linked information resource: Genomic correlates of response to immune checkpoint therapies in clear cell renal cell carcinoma.

Genomic correlates of response to immune checkpoint therapies in clear cell renal cell carcinoma.
PubMed Identifier: 29301960
author list: Miao D, Margolis CA, Gao W, Voss MH, Li W, Martini DJ, Norton C, Bossé D, Wankowicz SM, Cullen D, Horak C, Wind-Rotolo M, Tracy A, Giannakis M, Hodi FS, Drake CG, Ball MW, Allaf ME, Snyder A, Hellmann MD, Ho T, Motzer RJ, Signoretti S, Kaelin WG, Choueiri TK, Van Allen EM
published in: Science (New York, N.Y.)
information resource reference: Genomic correlates of response to immune checkpoint therapies in clear cell renal cell carcinoma. Science. 2018 Feb 16; 359(6377):801-806.
journal title abbreviation: Science
publication date: 2018-01-04T00:00:00
year: 2018
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1036775
type: Authorship
author rank in publication: 14
linked author: Van Allen, Eliezer
linked information resource: Interactive or static reports to guide clinical interpretation of cancer genomics.

Interactive or static reports to guide clinical interpretation of cancer genomics.
PubMed Identifier: 29315417
author list: Gray SW, Gagan J, Cerami E, Cronin AM, Uno H, Oliver N, Lowenstein C, Lederman R, Revette A, Suarez A, Lee C, Bryan J, Sholl L, Van Allen EM
published in: Journal of the American Medical Informatics Association : JAMIA
information resource reference: Interactive or static reports to guide clinical interpretation of cancer genomics. J Am Med Inform Assoc. 2018 05 01; 25(5):458-464.
journal title abbreviation: J Am Med Inform Assoc
publication date: 2018-05-01T00:00:00
year: 2018
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1040807
type: Authorship
author rank in publication: 10
linked author: Van Allen, Eliezer
linked information resource: Change in Neutrophil-to-lymphocyte ratio (NLR) in response to immune checkpoint blockade for metastatic renal cell carcinoma.

Change in Neutrophil-to-lymphocyte ratio (NLR) in response to immune checkpoint blockade for metastatic renal cell carcinoma.
PubMed Identifier: 29353553
author list: Lalani AA, Xie W, Martini DJ, Steinharter JA, Norton CK, Krajewski KM, Duquette A, Bossé D, Bellmunt J, Van Allen EM, McGregor BA, Creighton CJ, Harshman LC, Choueiri TK
published in: Journal for immunotherapy of cancer
information resource reference: Change in Neutrophil-to-lymphocyte ratio (NLR) in response to immune checkpoint blockade for metastatic renal cell carcinoma. J Immunother Cancer. 2018 01 22; 6(1):5.
journal title abbreviation: J Immunother Cancer
publication date: 2018-01-22T00:00:00
year: 2018
type: Academic Article
type: Article
type: Document
type: Information Resource

Molecular origins and evolution to chemoresistance in germ cell tumors
end date: 2023-01-31
principal investigator name: VAN ALLEN, ELIEZER M
start date: 2018-02-01
type: Grant
sponsor award id: R01CA222574

Principal Investigator
type: Researcher Role
researcher role of: Van Allen, Eliezer
contributes to: Molecular origins and evolution to chemoresistance in germ cell tumors