Kagan, Jonathan
eCommons Login: JCK17
first name: Jonathan
last name: Kagan
coauthor of: Evavold, Charles
coauthor of: Zanoni, Ivan
coauthor of: Ragland, Stephanie
coauthor of: Lieberman, Judy
coauthor of: Okin, Daniel
full name: Jonathan C. Kagan, Ph.D.
has faculty rank: Full Professor
has network: selected publications
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latitude: 42.33743600000000
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Person ID: 36686
person in primary position: Marian R. Neutra, PhD Professor of Pediatrics
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similar to: Colonna, Marco
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similar to: Lieberman, Judy
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selected publications: Authorship 1852772
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Authorship 1045767
type: Authorship
author rank in publication: 1
linked author: Kagan, Jonathan
linked information resource: Biological constraint, cultural variety, and psychological structures.

Authorship 1049819
type: Authorship
author rank in publication: 5
linked author: Kagan, Jonathan
linked information resource: STING-dependent translation inhibition restricts RNA virus replication.

Authorship 1048019
type: Authorship
author rank in publication: 1
linked author: Kagan, Jonathan
linked information resource: NIAID Division of AIDS flow cytometry quality assessment program.

STING-dependent translation inhibition restricts RNA virus replication.
PubMed Identifier: 29440426
author list: Franz KM, Neidermyer WJ, Tan YJ, Whelan SPJ, Kagan JC
published in: Proceedings of the National Academy of Sciences of the United States of America
information resource reference: STING-dependent translation inhibition restricts RNA virus replication. Proc Natl Acad Sci U S A. 2018 02 27; 115(9):E2058-E2067.
journal title abbreviation: Proc Natl Acad Sci U S A
publication date: 2018-02-12T00:00:00
year: 2018
type: Academic Article
type: Article
type: Document
type: Information Resource

Biological constraint, cultural variety, and psychological structures.
PubMed Identifier: 11411164
author list: Kagan J
published in: Annals of the New York Academy of Sciences
information resource reference: Biological constraint, cultural variety, and psychological structures. Ann N Y Acad Sci. 2001 May; 935:177-90.
journal title abbreviation: Ann N Y Acad Sci
publication date: 2001-05-01T00:00:00
year: 2001
type: Academic Article
type: Article
type: Document
type: Information Resource

Serum neopterin, an immune activation marker, independently predicts disease progression in advanced HIV-1 infection.
PubMed Identifier: 15736019
author list: Mildvan D, Spritzler J, Grossberg SE, Fahey JL, Johnston DM, Schock BR, Kagan J
published in: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
information resource reference: Serum neopterin, an immune activation marker, independently predicts disease progression in advanced HIV-1 infection. Clin Infect Dis. 2005 Mar 15; 40(6):853-8.
journal title abbreviation: Clin Infect Dis
publication date: 2005-02-18T00:00:00
year: 2005
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1057558
type: Authorship
author rank in publication: 13
linked author: Kagan, Jonathan
linked information resource: Retraction Notice to: The Unfolded Protein Response Element IRE1a Senses Bacterial Proteins Invading the ER to Activate RIG-I and Innate Immune Signaling.

Authorship 1059989
type: Authorship
author rank in publication: 9
linked author: Kagan, Jonathan
linked information resource: The IAP-antagonist ARTS initiates caspase activation upstream of cytochrome C and SMAC/Diablo.

Retraction Notice to: The Unfolded Protein Response Element IRE1a Senses Bacterial Proteins Invading the ER to Activate RIG-I and Innate Immune Signaling.
PubMed Identifier: 29649448
author list: Cho JA, Lee AH, Platzer B, Cross BCS, Gardner BM, De Luca H, Luong P, Harding HP, Glimcher LH, Walter P, Fiebiger E, Ron D, Kagan JC, Lencer WI
published in: Cell host & microbe
information resource reference: Retraction Notice to: The Unfolded Protein Response Element IRE1a Senses Bacterial Proteins Invading the ER to Activate RIG-I and Innate Immune Signaling. Cell Host Microbe. 2018 04 11; 23(4):571.
journal title abbreviation: Cell Host Microbe
publication date: 2018-04-11T00:00:00
year: 2018
type: Academic Article
type: Article
type: Document
type: Information Resource

The IAP-antagonist ARTS initiates caspase activation upstream of cytochrome C and SMAC/Diablo.
PubMed Identifier: 21869827
author list: Edison N, Zuri D, Maniv I, Bornstein B, Lev T, Gottfried Y, Kemeny S, Garcia-Fernandez M, Kagan J, Larisch S
published in: Cell death and differentiation
information resource reference: The IAP-antagonist ARTS initiates caspase activation upstream of cytochrome C and SMAC/Diablo. Cell Death Differ. 2012 Feb; 19(2):356-68.
journal title abbreviation: Cell Death Differ
publication date: 2011-08-26T00:00:00
year: 2011
type: Academic Article
type: Article
type: Document
type: Information Resource

Defining the subcellular sites of innate immune signal transduction.
PubMed Identifier: 22817912
author list: Kagan JC
published in: Trends in immunology
information resource reference: Defining the subcellular sites of innate immune signal transduction. Trends Immunol. 2012 Sep; 33(9):442-8.
journal title abbreviation: Trends Immunol
publication date: 2012-07-18T00:00:00
year: 2012
type: Academic Article
type: Article
type: Document
type: Information Resource

Recycling endosomes and TLR signaling--the Rab11 GTPase leads the way.
PubMed Identifier: 21029967
author list: Kagan JC
published in: Immunity
information resource reference: Recycling endosomes and TLR signaling--the Rab11 GTPase leads the way. Immunity. 2010 Oct 29; 33(4):578-80.
journal title abbreviation: Immunity
publication date: 2010-10-29T00:00:00
year: 2010
type: Academic Article
type: Article
type: Document
type: Information Resource

Interferon ß is associated with type 1 interferon-inducible gene expression in dermatomyositis.
PubMed Identifier: 21177291
author list: Liao AP, Salajegheh M, Nazareno R, Kagan JC, Jubin RG, Greenberg SA
published in: Annals of the rheumatic diseases
information resource reference: Interferon ß is associated with type 1 interferon-inducible gene expression in dermatomyositis. Ann Rheum Dis. 2011 May; 70(5):831-6.
journal title abbreviation: Ann Rheum Dis
publication date: 2010-12-21T00:00:00
year: 2010
type: Academic Article
type: Article
type: Document
type: Information Resource

A 3-year follow-up of children with and without behavioral inhibition.
PubMed Identifier: 8340303
author list: Biederman J, Rosenbaum JF, Bolduc-Murphy EA, Faraone SV, Chaloff J, Hirshfeld DR, Kagan J
published in: Journal of the American Academy of Child and Adolescent Psychiatry
information resource reference: A 3-year follow-up of children with and without behavioral inhibition. J Am Acad Child Adolesc Psychiatry. 1993 Jul; 32(4):814-21.
journal title abbreviation: J Am Acad Child Adolesc Psychiatry
publication date: 1993-07-01T00:00:00
year: 1993
type: Academic Article
type: Article
type: Document
type: Information Resource

CD14 controls the LPS-induced endocytosis of Toll-like receptor 4.
PubMed Identifier: 22078883
author list: Zanoni I, Ostuni R, Marek LR, Barresi S, Barbalat R, Barton GM, Granucci F, Kagan JC
published in: Cell
information resource reference: CD14 controls the LPS-induced endocytosis of Toll-like receptor 4. Cell. 2011 Nov 11; 147(4):868-80.
journal title abbreviation: Cell
publication date: 2011-11-11T00:00:00
year: 2011
type: Academic Article
type: Article
type: Document
type: Information Resource

A C-terminal translocation signal required for Dot/Icm-dependent delivery of the Legionella RalF protein to host cells.
PubMed Identifier: 15613486
author list: Nagai H, Cambronne ED, Kagan JC, Amor JC, Kahn RA, Roy CR
published in: Proceedings of the National Academy of Sciences of the United States of America
information resource reference: A C-terminal translocation signal required for Dot/Icm-dependent delivery of the Legionella RalF protein to host cells. Proc Natl Acad Sci U S A. 2005 Jan 18; 102(3):826-31.
journal title abbreviation: Proc Natl Acad Sci U S A
publication date: 2004-12-21T00:00:00
year: 2004
type: Academic Article
type: Article
type: Document
type: Information Resource

"Complementing" toll signaling.
PubMed Identifier: 20442416
author list: Kagan JC
published in: Science signaling
information resource reference: "Complementing" toll signaling. Sci Signal. 2010 May 04; 3(120):pe15.
journal title abbreviation: Sci Signal
publication date: 2010-05-04T00:00:00
year: 2010
type: Academic Article
type: Article
type: Document
type: Information Resource

Interlaboratory variability of CD8 subset measurements by flow cytometry and its applications to multicenter clinical trials. NAID/NICHD Women and Infants Transmission Study Group.
PubMed Identifier: 7583925
author list: Landay AL, Brambilla D, Pitt J, Hillyer G, Golenbock D, Moye J, Landesman S, Kagan J
published in: Clinical and diagnostic laboratory immunology
information resource reference: Interlaboratory variability of CD8 subset measurements by flow cytometry and its applications to multicenter clinical trials. NAID/NICHD Women and Infants Transmission Study Group. Clin Diagn Lab Immunol. 1995 Jul; 2(4):462-8.
journal title abbreviation: Clin Diagn Lab Immunol
publication date: 1995-07-01T00:00:00
year: 1995
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1088111
type: Authorship
author rank in publication: 6
linked author: Kagan, Jonathan
linked information resource: An Antiviral Branch of the IL-1 Signaling Pathway Restricts Immune-Evasive Virus Replication.

An Antiviral Branch of the IL-1 Signaling Pathway Restricts Immune-Evasive Virus Replication.
PubMed Identifier: 30100266
author list: Orzalli MH, Smith A, Jurado KA, Iwasaki A, Garlick JA, Kagan JC
published in: Molecular cell
information resource reference: An Antiviral Branch of the IL-1 Signaling Pathway Restricts Immune-Evasive Virus Replication. Mol Cell. 2018 09 06; 71(5):825-840.e6.
journal title abbreviation: Mol Cell
publication date: 2018-08-09T00:00:00
year: 2018
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 11693
type: Authorship
author rank in publication: 7
linked author: Kagan, Jonathan
linked information resource: MyD88-dependent TLR1/2 signals educate dendritic cells with gut-specific imprinting properties.

Standardization of absolute CD4+ lymphocyte counts across laboratories: an evaluation of the Ortho CytoronAbsolute flow cytometry system on normal donors.
PubMed Identifier: 8556951
author list: Connelly MC, Knight M, Giorgi JV, Kagan J, Landay AL, Parker JW, Page E, Spino C, Wilkening C, Mercolino TJ
published in: Cytometry
information resource reference: Standardization of absolute CD4+ lymphocyte counts across laboratories: an evaluation of the Ortho CytoronAbsolute flow cytometry system on normal donors. Cytometry. 1995 Sep 15; 22(3):200-10.
journal title abbreviation: Cytometry
publication date: 1995-09-15T00:00:00
year: 1995
type: Academic Article
type: Article
type: Document
type: Information Resource

A cell biological view of Toll-like receptor function: regulation through compartmentalization.
PubMed Identifier: 19556980
author list: Barton GM, Kagan JC
published in: Nature reviews. Immunology
information resource reference: A cell biological view of Toll-like receptor function: regulation through compartmentalization. Nat Rev Immunol. 2009 Aug; 9(8):535-42.
journal title abbreviation: Nat Rev Immunol
publication date: 2009-06-26T00:00:00
year: 2009
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1100912
type: Authorship
author rank in publication: 5
linked author: Kagan, Jonathan
linked information resource: Vector Immunity and Evolutionary Ecology: The Harmonious Dissonance.

Vector Immunity and Evolutionary Ecology: The Harmonious Dissonance.
PubMed Identifier: 30301592
author list: Shaw DK, Tate AT, Schneider DS, Levashina EA, Kagan JC, Pal U, Fikrig E, Pedra JHF
published in: Trends in immunology
information resource reference: Vector Immunity and Evolutionary Ecology: The Harmonious Dissonance. Trends Immunol. 2018 11; 39(11):862-873.
journal title abbreviation: Trends Immunol
publication date: 2018-10-06T00:00:00
year: 2018
type: Academic Article
type: Article
type: Document
type: Information Resource

Daylength during pregnancy and shyness in children: results from northern and southern hemispheres.
PubMed Identifier: 9298636
author list: Gortmaker SL, Kagan J, Caspi A, Silva PA
published in: Developmental psychobiology
information resource reference: Daylength during pregnancy and shyness in children: results from northern and southern hemispheres. Dev Psychobiol. 1997 Sep; 31(2):107-14.
journal title abbreviation: Dev Psychobiol
publication date: 1997-09-01T00:00:00
year: 1997
type: Academic Article
type: Article
type: Document
type: Information Resource

Influences of gender and social class on adolescents' perceptions of health.
PubMed Identifier: 9308867
author list: Goodman E, Amick BC, Rezendes MO, Tarlov AR, Rogers WH, Kagan J
published in: Archives of pediatrics & adolescent medicine
information resource reference: Influences of gender and social class on adolescents' perceptions of health. Arch Pediatr Adolesc Med. 1997 Sep; 151(9):899-904.
journal title abbreviation: Arch Pediatr Adolesc Med
publication date: 1997-09-01T00:00:00
year: 1997
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1109747
type: Authorship
author rank in publication: 2
linked author: Kagan, Jonathan
linked information resource: The Fly Way of Antiviral Resistance and Disease Tolerance.

The Fly Way of Antiviral Resistance and Disease Tolerance.
PubMed Identifier: 30366519
author list: Chow J, Kagan JC
published in: Advances in immunology
information resource reference: The Fly Way of Antiviral Resistance and Disease Tolerance. Adv Immunol. 2018; 140:59-93.
journal title abbreviation: Adv Immunol
publication date: 2018-09-18T00:00:00
year: 2018
type: Academic Article
type: Article
type: Document
type: Information Resource

Startle potentiation by threat of aversive stimuli and darkness in adolescents: a multi-site study.
PubMed Identifier: 10192009
author list: Grillon C, Merikangas KR, Dierker L, Snidman N, Arriaga RI, Kagan J, Donzella B, Dikel T, Nelson C
published in: International journal of psychophysiology : official journal of the International Organization of Psychophysiology
information resource reference: Startle potentiation by threat of aversive stimuli and darkness in adolescents: a multi-site study. Int J Psychophysiol. 1999 Apr; 32(1):63-73.
journal title abbreviation: Int J Psychophysiol
publication date: 1999-04-01T00:00:00
year: 1999
type: Academic Article
type: Article
type: Document
type: Information Resource

Ragland, Stephanie
eCommons Login: SR403
first name: Stephanie
last name: Ragland
full name: Stephanie Ragland, Ph.D.
has faculty rank: Fellow or Post Doc
Person ID: 174950
person in primary position: Research Fellow in Pediatrics
type: Agent
type: Person
preferred title: Research Fellow in Pediatrics

Guideline for flow cytometric immunophenotyping: a report from the National Institute of Allergy and Infectious Diseases, Division of AIDS.
PubMed Identifier: 8243200
author list: Calvelli T, Denny TN, Paxton H, Gelman R, Kagan J
published in: Cytometry
information resource reference: Guideline for flow cytometric immunophenotyping: a report from the National Institute of Allergy and Infectious Diseases, Division of AIDS. Cytometry. 1993 Oct; 14(7):702-15.
journal title abbreviation: Cytometry
publication date: 1993-10-01T00:00:00
year: 1993
type: Academic Article
type: Article
type: Document
type: Information Resource

Cellular and Molecular Aspects of Legionella pneumophila transport to the endoplasmic reticulum
author list: Jonathan C. Kagan
published in: Cellular and Molecular Aspects of Legionella pneumophila transport to the endoplasmic reticulum
information resource reference: Cellular and Molecular Aspects of Legionella pneumophila transport to the endoplasmic reticulum. 2003.
publication date: 2003-05-24T00:00:00
year: 2003
type: Academic Article
type: Article
type: Document
type: Information Resource

Safety of autologous, ex vivo-expanded human immunodeficiency virus (HIV)-specific cytotoxic T-lymphocyte infusion in HIV-infected patients.
PubMed Identifier: 9310470
author list: Lieberman J, Skolnik PR, Parkerson GR, Fabry JA, Landry B, Bethel J, Kagan J
published in: Blood
information resource reference: Safety of autologous, ex vivo-expanded human immunodeficiency virus (HIV)-specific cytotoxic T-lymphocyte infusion in HIV-infected patients. Blood. 1997 Sep 15; 90(6):2196-206.
journal title abbreviation: Blood
publication date: 1997-09-15T00:00:00
year: 1997
type: Academic Article
type: Article
type: Document
type: Information Resource

A bacterial guanine nucleotide exchange factor activates ARF on Legionella phagosomes.
PubMed Identifier: 11809974
author list: Nagai H, Kagan JC, Zhu X, Kahn RA, Roy CR
published in: Science (New York, N.Y.)
information resource reference: A bacterial guanine nucleotide exchange factor activates ARF on Legionella phagosomes. Science. 2002 Jan 25; 295(5555):679-82.
journal title abbreviation: Science
publication date: 2002-01-25T00:00:00
year: 2002
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1125012
type: Authorship
author rank in publication: 2
linked author: Kagan, Jonathan
linked information resource: Defying Death: The (W)hole Truth about the Fate of GSDMD Pores.

Defying Death: The (W)hole Truth about the Fate of GSDMD Pores.
PubMed Identifier: 30650374
author list: Evavold CL, Kagan JC
published in: Immunity
information resource reference: Defying Death: The (W)hole Truth about the Fate of GSDMD Pores. Immunity. 2019 01 15; 50(1):15-17.
journal title abbreviation: Immunity
publication date: 2019-01-15T00:00:00
year: 2019
type: Academic Article
type: Article
type: Document
type: Information Resource

TRAM couples endocytosis of Toll-like receptor 4 to the induction of interferon-beta.
PubMed Identifier: 18297073
author list: Kagan JC, Su T, Horng T, Chow A, Akira S, Medzhitov R
published in: Nature immunology
information resource reference: TRAM couples endocytosis of Toll-like receptor 4 to the induction of interferon-beta. Nat Immunol. 2008 Apr; 9(4):361-8.
journal title abbreviation: Nat Immunol
publication date: 2008-02-24T00:00:00
year: 2008
type: Academic Article
type: Article
type: Document
type: Information Resource

Regulation of lipopolysaccharide-induced translation of tumor necrosis factor-alpha by the toll-like receptor 4 adaptor protein TRAM.
PubMed Identifier: 21494017
author list: Wang L, Trebicka E, Fu Y, Waggoner L, Akira S, Fitzgerald KA, Kagan JC, Cherayil BJ
published in: Journal of innate immunity
information resource reference: Regulation of lipopolysaccharide-induced translation of tumor necrosis factor-alpha by the toll-like receptor 4 adaptor protein TRAM. J Innate Immun. 2011; 3(5):437-46.
journal title abbreviation: J Innate Immun
publication date: 2011-04-14T00:00:00
year: 2011
type: Academic Article
type: Article
type: Document
type: Information Resource

Phosphoinositide binding by the Toll adaptor dMyD88 controls antibacterial responses in Drosophila.
PubMed Identifier: 22464168
author list: Marek LR, Kagan JC
published in: Immunity
information resource reference: Phosphoinositide binding by the Toll adaptor dMyD88 controls antibacterial responses in Drosophila. Immunity. 2012 Apr 20; 36(4):612-22.
journal title abbreviation: Immunity
publication date: 2012-03-29T00:00:00
year: 2012
type: Academic Article
type: Article
type: Document
type: Information Resource

Phagosome as the organelle linking innate and adaptive immunity.
PubMed Identifier: 22577865
author list: Kagan JC, Iwasaki A
published in: Traffic (Copenhagen, Denmark)
information resource reference: Phagosome as the organelle linking innate and adaptive immunity. Traffic. 2012 Aug; 13(8):1053-61.
journal title abbreviation: Traffic
publication date: 2012-06-12T00:00:00
year: 2012
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1135364
type: Authorship
author rank in publication: 7
linked author: Kagan, Jonathan
linked information resource: Phosphoinositide Interactions Position cGAS at the Plasma Membrane to Ensure Efficient Distinction between Self- and Viral DNA.

Authorship 1137822
type: Authorship
author rank in publication: 2
linked author: Kagan, Jonathan
linked information resource: Innate Immune Signaling Organelles Display Natural and Programmable Signaling Flexibility.

Phosphoinositide Interactions Position cGAS at the Plasma Membrane to Ensure Efficient Distinction between Self- and Viral DNA.
PubMed Identifier: 30827685
author list: Barnett KC, Coronas-Serna JM, Zhou W, Ernandes MJ, Cao A, Kranzusch PJ, Kagan JC
published in: Cell
information resource reference: Phosphoinositide Interactions Position cGAS at the Plasma Membrane to Ensure Efficient Distinction between Self- and Viral DNA. Cell. 2019 03 07; 176(6):1432-1446.e11.
journal title abbreviation: Cell
publication date: 2019-02-28T00:00:00
year: 2019
type: Academic Article
type: Article
type: Document
type: Information Resource

Innate Immune Signaling Organelles Display Natural and Programmable Signaling Flexibility.
PubMed Identifier: 30853218
author list: Tan Y, Kagan JC
published in: Cell
information resource reference: Innate Immune Signaling Organelles Display Natural and Programmable Signaling Flexibility. Cell. 2019 04 04; 177(2):384-398.e11.
journal title abbreviation: Cell
publication date: 2019-03-07T00:00:00
year: 2019
type: Academic Article
type: Article
type: Document
type: Information Resource

Receptors, Pattern Recognition
MeSH DescriptorUI: D051192
MeSH semantic group name: Chemicals & Drugs
number of authors: 53
number of publications: 88
uniqueness weight: 0.899937
type: Concept

Toll-Like Receptors
MeSH DescriptorUI: D051193
MeSH semantic group name: Chemicals & Drugs
number of authors: 347
number of publications: 596
uniqueness weight: 0.752635
type: Concept

Inflammasomes
MeSH DescriptorUI: D058847
MeSH semantic group name: Chemicals & Drugs
number of authors: 355
number of publications: 616
uniqueness weight: 0.650918
type: Concept

Experimental Medicine Unit - CCIB
type: Division
type: Organization

Pulmonary and Critical Care Medicine
type: Division
type: Organization

Immunity, Innate
MeSH DescriptorUI: D007113
MeSH semantic group name: Physiology
number of authors: 1370
number of publications: 3329
uniqueness weight: 0.399633
type: Concept

Authorship 1149196
type: Authorship
author rank in publication: 3
linked author: Kagan, Jonathan
linked information resource: Depression and allergies: survey of a nonclinical population.

Authorship 1148531
type: Authorship
author rank in publication: 4
linked author: Kagan, Jonathan
linked information resource: Modular Architecture of the STING C-Terminal Tail Allows Interferon and NF-?B Signaling Adaptation.

Authorship 1149394
type: Authorship
author rank in publication: 3
linked author: Kagan, Jonathan
linked information resource: Is allergic rhinitis more frequent in young adults with extreme shyness? A preliminary survey.

Is allergic rhinitis more frequent in young adults with extreme shyness? A preliminary survey.
PubMed Identifier: 2247557
author list: Bell IR, Jasnoski ML, Kagan J, King DS
published in: Psychosomatic medicine
information resource reference: Is allergic rhinitis more frequent in young adults with extreme shyness? A preliminary survey. Psychosom Med. 1990 Sep-Oct; 52(5):517-25.
journal title abbreviation: Psychosom Med
publication date: 1990-09-01T00:00:00
year: 1990
type: Academic Article
type: Article
type: Document
type: Information Resource

Modular Architecture of the STING C-Terminal Tail Allows Interferon and NF-?B Signaling Adaptation.
PubMed Identifier: 31018131
author list: de Oliveira Mann CC, Orzalli MH, King DS, Kagan JC, Lee ASY, Kranzusch PJ
published in: Cell reports
information resource reference: Modular Architecture of the STING C-Terminal Tail Allows Interferon and NF-?B Signaling Adaptation. Cell Rep. 2019 04 23; 27(4):1165-1175.e5.
journal title abbreviation: Cell Rep
publication date: 2019-04-23T00:00:00
year: 2019
type: Academic Article
type: Article
type: Document
type: Information Resource

Depression and allergies: survey of a nonclinical population.
PubMed Identifier: 1866437
author list: Bell IR, Jasnoski ML, Kagan J, King DS
published in: Psychotherapy and psychosomatics
information resource reference: Depression and allergies: survey of a nonclinical population. Psychother Psychosom. 1991; 55(1):24-31.
journal title abbreviation: Psychother Psychosom
publication date: 1991-01-01T00:00:00
year: 1991
type: Academic Article
type: Article
type: Document
type: Information Resource

Signal Transduction
MeSH DescriptorUI: D015398
MeSH semantic group name: Physiology
number of authors: 4851
number of publications: 24369
uniqueness weight: 0.193083
type: Concept

Medicine
type: Department
type: Organization

Pediatrics
type: Department
type: Organization

Gastroenterology
type: Division
type: Organization

Hematology/Oncology
type: Division
type: Organization

Beth Israel Deaconess Medical Center
type: Organization

Boston Children's Hospital
type: Organization

Massachusetts Eye and Ear Infirmary
type: Organization

Massachusetts General Hospital
type: Organization

Lieberman, Judy
eCommons Login: JL29
first name: Judy
last name: Lieberman
full name: Judy Lieberman, M.D., Ph.D.
has faculty rank: Full Professor
latitude: 42.33594500000000
longitude: -71.10295800000000
Person ID: 34254
person in primary position: Professor of Pediatrics
type: Agent
type: Person
preferred title: Professor of Pediatrics

Lightdale, Jenifer
first name: Jenifer
last name: Lightdale
full name: Jenifer Ruth Lightdale, M.D.
has faculty rank: Full Professor
latitude: 42.33743600000000
longitude: -71.10544700000000
Person ID: 44181
person in primary position: Professor of Pediatrics
type: Agent
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preferred title: Professor of Pediatrics

Hron, Bridget
eCommons Login: BMC10
first name: Bridget
last name: Hron
full name: Bridget Mary Hron, M.D.
has faculty rank: Assistant Professor
latitude: 42.33743600000000
longitude: -71.10544700000000
Person ID: 84890
person in primary position: Assistant Professor of Pediatrics
type: Agent
type: Person
preferred title: Assistant Professor of Pediatrics

Authorship 1158063
type: Authorship
author rank in publication: 2
linked author: Kagan, Jonathan
linked information resource: Host-Encoded Sensors of Bacteria: Our Windows into the Microbial World.

Host-Encoded Sensors of Bacteria: Our Windows into the Microbial World.
PubMed Identifier: 31152521
author list: Odendall C, Kagan JC
published in: Microbiology spectrum
information resource reference: Host-Encoded Sensors of Bacteria: Our Windows into the Microbial World. Microbiol Spectr. 2019 05; 7(3).
journal title abbreviation: Microbiol Spectr
publication date: 2019-05-01T00:00:00
year: 2019
type: Academic Article
type: Article
type: Document
type: Information Resource

Bousvaros, Athos
eCommons Login: AB16
first name: Athos
last name: Bousvaros
full name: Athos Bousvaros, M.D.
has faculty rank: Full Professor
latitude: 42.33743600000000
longitude: -71.10544700000000
Person ID: 30137
person in primary position: Professor of Pediatrics
type: Agent
type: Person
preferred title: Professor of Pediatrics

Kamin, Daniel
eCommons Login: DSK3
first name: Daniel
last name: Kamin
full name: Daniel S Kamin, M.D.
has faculty rank: Assistant Professor
latitude: 42.33743600000000
longitude: -71.10544700000000
Person ID: 2862
person in primary position: Assistant Professor of Pediatrics
type: Agent
type: Person
preferred title: Assistant Professor of Pediatrics

Wolf, Anne
eCommons Login: AAW3
first name: Anne
last name: Wolf
full name: Anne Armour Wolf, M.D.
has faculty rank: Assistant Professor
latitude: 42.33743600000000
longitude: -71.10544700000000
Person ID: 84872
person in primary position: Assistant Professor of Pediatrics
type: Agent
type: Person
preferred title: Assistant Professor of Pediatrics

selected publications
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research areas
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similar to
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predicate: similar to
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Authorship 1161043
type: Authorship
author rank in publication: 2
linked author: Kagan, Jonathan
linked information resource: Lipids that directly regulate innate immune signal transduction.

Lipids that directly regulate innate immune signal transduction.
PubMed Identifier: 31180799
author list: Barnett KC, Kagan JC
published in: Innate immunity
information resource reference: Lipids that directly regulate innate immune signal transduction. Innate Immun. 2020 01; 26(1):4-14.
journal title abbreviation: Innate Immun
publication date: 2019-06-10T00:00:00
year: 2019
type: Academic Article
type: Article
type: Document
type: Information Resource

Levy, Ofer
eCommons Login: OL1
first name: Ofer
last name: Levy
full name: Ofer Levy, M.D., Ph.D.
has faculty rank: Full Professor
latitude: 42.33743600000000
longitude: -71.10544700000000
Person ID: 45538
person in primary position: Professor of Pediatrics
type: Agent
type: Person
preferred title: Professor of Pediatrics

Authorship 1165396
type: Authorship
author rank in publication: 7
linked author: Kagan, Jonathan
linked information resource: Patterns, dynamics and consequences of microplastic ingestion by the temperate coral, Astrangia poculata.

Authorship 1164938
type: Authorship
author rank in publication: 2
linked author: Kagan, Jonathan
linked information resource: In vitro selection of murine antigen-specific T-lymphocytes. I. Description of selection procedure.

Authorship 1165157
type: Authorship
author rank in publication: 2
linked author: Kagan, Jonathan
linked information resource: Antigen-induced proliferation of murine T-lymphocytes in vitro. II. The effect of different macrophage populations on the antigen-induced proliferative response.

Authorship 1165020
type: Authorship
author rank in publication: 1
linked author: Kagan, Jonathan
linked information resource: Antigen-induced proliferation of murine T-lymphocytes in vitro. I. Characterization of the lymphocyte culture system.

Patterns, dynamics and consequences of microplastic ingestion by the temperate coral, Astrangia poculata.
PubMed Identifier: 31238843
author list: Rotjan RD, Sharp KH, Gauthier AE, Yelton R, Lopez EMB, Carilli J, Kagan JC, Urban-Rich J
published in: Proceedings. Biological sciences
information resource reference: Patterns, dynamics and consequences of microplastic ingestion by the temperate coral, Astrangia poculata. Proc Biol Sci. 2019 06 26; 286(1905):20190726.
journal title abbreviation: Proc Biol Sci
publication date: 2019-06-26T00:00:00
year: 2019
type: Academic Article
type: Article
type: Document
type: Information Resource

Antigen-induced proliferation of murine T-lymphocytes in vitro. I. Characterization of the lymphocyte culture system.
PubMed Identifier: 6968800
author list: Kagan J, Ben-Sasson SZ
published in: Journal of immunological methods
information resource reference: Antigen-induced proliferation of murine T-lymphocytes in vitro. I. Characterization of the lymphocyte culture system. J Immunol Methods. 1980; 37(1):15-27.
journal title abbreviation: J Immunol Methods
publication date: 1980-01-01T00:00:00
year: 1980
type: Academic Article
type: Article
type: Document
type: Information Resource

Antigen-induced proliferation of murine T-lymphocytes in vitro. II. The effect of different macrophage populations on the antigen-induced proliferative response.
PubMed Identifier: 6971903
author list: Ben-Sasson SZ, Kagan J
published in: Journal of immunological methods
information resource reference: Antigen-induced proliferation of murine T-lymphocytes in vitro. II. The effect of different macrophage populations on the antigen-induced proliferative response. J Immunol Methods. 1981; 41(3):321-31.
journal title abbreviation: J Immunol Methods
publication date: 1981-01-01T00:00:00
year: 1981
type: Academic Article
type: Article
type: Document
type: Information Resource

In vitro selection of murine antigen-specific T-lymphocytes. I. Description of selection procedure.
PubMed Identifier: 6169763
author list: Ben-Sasson SZ, Kagan J
published in: Journal of immunological methods
information resource reference: In vitro selection of murine antigen-specific T-lymphocytes. I. Description of selection procedure. J Immunol Methods. 1981; 42(3):291-304.
journal title abbreviation: J Immunol Methods
publication date: 1981-01-01T00:00:00
year: 1981
type: Academic Article
type: Article
type: Document
type: Information Resource

Szabo, Gyongyi
eCommons Login: GS14
first name: Gyongyi
last name: Szabo
full name: Gyongyi Szabo, M.D., Ph.D.
has faculty rank: Full Professor
Person ID: 28770
person in primary position: Professor of Medicine
type: Agent
type: Person
preferred title: Professor of Medicine

Authorship 1188113
type: Authorship
author rank in publication: 2
linked author: Kagan, Jonathan
linked information resource: Inflammasomes: Threat-Assessment Organelles of the Innate Immune System.

Authorship 1187308
type: Authorship
author rank in publication: 3
linked author: Kagan, Jonathan
linked information resource: Gasdermin D activity in inflammation and host defense.

Gasdermin D activity in inflammation and host defense.
PubMed Identifier: 31492708
author list: Lieberman J, Wu H, Kagan JC
published in: Science immunology
information resource reference: Gasdermin D activity in inflammation and host defense. Sci Immunol. 2019 09 06; 4(39).
journal title abbreviation: Sci Immunol
publication date: 2019-09-06T00:00:00
year: 2019
type: Academic Article
type: Article
type: Document
type: Information Resource

Inflammasomes: Threat-Assessment Organelles of the Innate Immune System.
PubMed Identifier: 31473100
author list: Evavold CL, Kagan JC
published in: Immunity
information resource reference: Inflammasomes: Threat-Assessment Organelles of the Innate Immune System. Immunity. 2019 10 15; 51(4):609-624.
journal title abbreviation: Immunity
publication date: 2019-08-28T00:00:00
year: 2019
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1201964
type: Authorship
author rank in publication: 10
linked author: Kagan, Jonathan
linked information resource: Asymmetric distribution of TLR3 leads to a polarized immune response in human intestinal epithelial cells.

Asymmetric distribution of TLR3 leads to a polarized immune response in human intestinal epithelial cells.
PubMed Identifier: 31686029
author list: Stanifer ML, Mukenhirn M, Muenchau S, Pervolaraki K, Kanaya T, Albrecht D, Odendall C, Hielscher T, Haucke V, Kagan JC, Bartfeld S, Ohno H, Boulant S
published in: Nature microbiology
information resource reference: Asymmetric distribution of TLR3 leads to a polarized immune response in human intestinal epithelial cells. Nat Microbiol. 2020 01; 5(1):181-191.
journal title abbreviation: Nat Microbiol
publication date: 2019-11-04T00:00:00
year: 2019
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1233383
type: Authorship
author rank in publication: 2
linked author: Kagan, Jonathan
linked information resource: Toll-like Receptors and the Control of Immunity.

Toll-like Receptors and the Control of Immunity.
PubMed Identifier: 32164908
author list: Fitzgerald KA, Kagan JC
published in: Cell
information resource reference: Toll-like Receptors and the Control of Immunity. Cell. 2020 03 19; 180(6):1044-1066.
journal title abbreviation: Cell
publication date: 2020-03-11T00:00:00
year: 2020
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 186749
type: Authorship
author rank in publication: 1
linked author: Kagan, Jonathan
linked information resource: Analysis of Rab1 recruitment to vacuoles containing Legionella pneumophila.

Authorship 142648
type: Authorship
author rank in publication: 2
linked author: Kagan, Jonathan
linked information resource: Phosphoinositide binding by the Toll adaptor dMyD88 controls antibacterial responses in Drosophila.

Authorship 173673
type: Authorship
author rank in publication: 6
linked author: Kagan, Jonathan
linked information resource: Comorbidity of parental anxiety disorders as risk for childhood-onset anxiety in inhibited children.

Authorship 1288265
type: Authorship
author rank in publication: 14
linked author: Kagan, Jonathan
linked information resource: HDAC6 mediates an aggresome-like mechanism for NLRP3 and pyrin inflammasome activation.

HDAC6 mediates an aggresome-like mechanism for NLRP3 and pyrin inflammasome activation.
PubMed Identifier: 32943500
author list: Magupalli VG, Negro R, Tian Y, Hauenstein AV, Di Caprio G, Skillern W, Deng Q, Orning P, Alam HB, Maliga Z, Sharif H, Hu JJ, Evavold CL, Kagan JC, Schmidt FI, Fitzgerald KA, Kirchhausen T, Li Y, Wu H
published in: Science (New York, N.Y.)
information resource reference: HDAC6 mediates an aggresome-like mechanism for NLRP3 and pyrin inflammasome activation. Science. 2020 09 18; 369(6510).
journal title abbreviation: Science
publication date: 2020-09-18T00:00:00
year: 2020
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1293287
type: Authorship
author rank in publication: 7
linked author: Kagan, Jonathan
linked information resource: Mitochondrial Reactive Oxygen Species Participate in Signaling Triggered by Heme in Macrophages and upon Hemolysis.

Mitochondrial Reactive Oxygen Species Participate in Signaling Triggered by Heme in Macrophages and upon Hemolysis.
PubMed Identifier: 33037139
author list: Prestes EB, Alves LS, Rodrigues DAS, Dutra FF, Fernandez PL, Paiva CN, Kagan JC, Bozza MT
published in: Journal of immunology (Baltimore, Md. : 1950)
information resource reference: Mitochondrial Reactive Oxygen Species Participate in Signaling Triggered by Heme in Macrophages and upon Hemolysis. J Immunol. 2020 11 15; 205(10):2795-2805.
journal title abbreviation: J Immunol
publication date: 2020-10-09T00:00:00
year: 2020
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1307029
type: Authorship
author rank in publication: 11
linked author: Kagan, Jonathan
linked information resource: Inflammasomes within Hyperactive Murine Dendritic Cells Stimulate Long-Lived T Cell-Mediated Anti-tumor Immunity.

Inflammasomes within Hyperactive Murine Dendritic Cells Stimulate Long-Lived T Cell-Mediated Anti-tumor Immunity.
PubMed Identifier: 33207188
author list: Zhivaki D, Borriello F, Chow OA, Doran B, Fleming I, Theisen DJ, Pallis P, Shalek AK, Sokol CL, Zanoni I, Kagan JC
published in: Cell reports
information resource reference: Inflammasomes within Hyperactive Murine Dendritic Cells Stimulate Long-Lived T Cell-Mediated Anti-tumor Immunity. Cell Rep. 2020 11 17; 33(7):108381.
journal title abbreviation: Cell Rep
publication date: 2020-11-17T00:00:00
year: 2020
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 144240
type: Authorship
author rank in publication: 1
linked author: Kagan, Jonathan
linked information resource: Signaling organelles of the innate immune system.

Authorship 217567
type: Authorship
author rank in publication: 5
linked author: Kagan, Jonathan
linked information resource: Microtubule motors control membrane dynamics of Salmonella-containing vacuoles.

Authorship 1337554
type: Authorship
author rank in publication: 15
linked author: Kagan, Jonathan
linked information resource: Deep-sea microbes as tools to refine the rules of innate immune pattern recognition.

Deep-sea microbes as tools to refine the rules of innate immune pattern recognition.
PubMed Identifier: 33712473
author list: Gauthier AE, Chandler CE, Poli V, Gardner FM, Tekiau A, Smith R, Bonham KS, Cordes EE, Shank TM, Zanoni I, Goodlett DR, Biller SJ, Ernst RK, Rotjan RD, Kagan JC
published in: Science immunology
information resource reference: Deep-sea microbes as tools to refine the rules of innate immune pattern recognition. Sci Immunol. 2021 03 12; 6(57).
journal title abbreviation: Sci Immunol
publication date: 2021-03-12T00:00:00
year: 2021
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1348635
type: Authorship
author rank in publication: 2
linked author: Kagan, Jonathan
linked information resource: Interferon-Independent Restriction of RNA Virus Entry and Replication by a Class of Damage-Associated Molecular Patterns.

Interferon-Independent Restriction of RNA Virus Entry and Replication by a Class of Damage-Associated Molecular Patterns.
PubMed Identifier: 33849978
author list: Ernandes MJ, Kagan JC
published in: mBio
information resource reference: Interferon-Independent Restriction of RNA Virus Entry and Replication by a Class of Damage-Associated Molecular Patterns. mBio. 2021 04 13; 12(2).
journal title abbreviation: mBio
publication date: 2021-04-13T00:00:00
year: 2021
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1355619
type: Authorship
author rank in publication: 6
linked author: Kagan, Jonathan
linked information resource: Virus-mediated inactivation of anti-apoptotic Bcl-2 family members promotes Gasdermin-E-dependent pyroptosis in barrier epithelial cells.

Virus-mediated inactivation of anti-apoptotic Bcl-2 family members promotes Gasdermin-E-dependent pyroptosis in barrier epithelial cells.
PubMed Identifier: 33979579
author list: Orzalli MH, Prochera A, Payne L, Smith A, Garlick JA, Kagan JC
published in: Immunity
information resource reference: Virus-mediated inactivation of anti-apoptotic Bcl-2 family members promotes Gasdermin-E-dependent pyroptosis in barrier epithelial cells. Immunity. 2021 07 13; 54(7):1447-1462.e5.
journal title abbreviation: Immunity
publication date: 2021-05-11T00:00:00
year: 2021
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1358219
type: Authorship
author rank in publication: 2
linked author: Kagan, Jonathan
linked information resource: NLRP3 inflammasomes that induce antitumor immunity.

Authorship 1359007
type: Authorship
author rank in publication: 1
linked author: Kagan, Jonathan
linked information resource: NIAID ClinRegs-a Public Database of Country Clinical Research Regulatory and Ethics Requirements: Design and Utilization Analysis.

NLRP3 inflammasomes that induce antitumor immunity.
PubMed Identifier: 34034975
author list: Zhivaki D, Kagan JC
published in: Trends in immunology
information resource reference: NLRP3 inflammasomes that induce antitumor immunity. Trends Immunol. 2021 07; 42(7):575-589.
journal title abbreviation: Trends Immunol
publication date: 2021-05-22T00:00:00
year: 2021
type: Academic Article
type: Article
type: Document
type: Information Resource

NIAID ClinRegs-a Public Database of Country Clinical Research Regulatory and Ethics Requirements: Design and Utilization Analysis.
PubMed Identifier: 34050748
author list: Kagan J, Goodman GN, Oh R, Whitworth D, Gladden D, Graves G, Nguyen A, Shrestha O, Burge G, Smolskis M, Andrews J, Cramer B, Lane HC
published in: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
information resource reference: NIAID ClinRegs-a Public Database of Country Clinical Research Regulatory and Ethics Requirements: Design and Utilization Analysis. Clin Infect Dis. 2021 10 05; 73(7):1296-1301.
journal title abbreviation: Clin Infect Dis
publication date: 2021-10-05T00:00:00
year: 2021
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1371636
type: Authorship
author rank in publication: 8
linked author: Kagan, Jonathan
linked information resource: Cloning, expression of the human substance K receptor, and analysis of its role in mitogenesis.

Authorship 1372219
type: Authorship
author rank in publication: 7
linked author: Kagan, Jonathan
linked information resource: Matrix lumican endocytosed by immune cells controls receptor ligand trafficking to promote TLR4 and restrict TLR9 in sepsis.

Cloning, expression of the human substance K receptor, and analysis of its role in mitogenesis.
PubMed Identifier: 1659297
author list: Cyr C, South V, Saltzman A, Felder S, Ricca GA, Jaye M, Huebner K, Kagan J, Croce CM, Schlessinger J
published in: Annals of the New York Academy of Sciences
information resource reference: Cloning, expression of the human substance K receptor, and analysis of its role in mitogenesis. Ann N Y Acad Sci. 1991; 632:426-7.
journal title abbreviation: Ann N Y Acad Sci
publication date: 1991-01-01T00:00:00
year: 1991
type: Academic Article
type: Article
type: Document
type: Information Resource

Matrix lumican endocytosed by immune cells controls receptor ligand trafficking to promote TLR4 and restrict TLR9 in sepsis.
PubMed Identifier: 34215697
author list: Maiti G, Frikeche J, Lam CY, Biswas A, Shinde V, Samanovic M, Kagan JC, Mulligan MJ, Chakravarti S
published in: Proceedings of the National Academy of Sciences of the United States of America
information resource reference: Matrix lumican endocytosed by immune cells controls receptor ligand trafficking to promote TLR4 and restrict TLR9 in sepsis. Proc Natl Acad Sci U S A. 2021 07 06; 118(27).
journal title abbreviation: Proc Natl Acad Sci U S A
publication date: 2021-07-06T00:00:00
year: 2021
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1377991
type: Authorship
author rank in publication: 11
linked author: Kagan, Jonathan
linked information resource: Control of gasdermin D oligomerization and pyroptosis by the Ragulator-Rag-mTORC1 pathway.

Control of gasdermin D oligomerization and pyroptosis by the Ragulator-Rag-mTORC1 pathway.
PubMed Identifier: 34289345
author list: Evavold CL, Hafner-Bratkovic I, Devant P, D'Andrea JM, Ngwa EM, Boršic E, Doench JG, LaFleur MW, Sharpe AH, Thiagarajah JR, Kagan JC
published in: Cell
information resource reference: Control of gasdermin D oligomerization and pyroptosis by the Ragulator-Rag-mTORC1 pathway. Cell. 2021 08 19; 184(17):4495-4511.e19.
journal title abbreviation: Cell
publication date: 2021-07-21T00:00:00
year: 2021
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 194028
type: Authorship
author rank in publication: 2
linked author: Kagan, Jonathan
linked information resource: A bacterial guanine nucleotide exchange factor activates ARF on Legionella phagosomes.

Authorship 1392265
type: Authorship
author rank in publication: 10
linked author: Kagan, Jonathan
linked information resource: TBK1 and IKKe act like an OFF switch to limit NLRP3 inflammasome pathway activation.

TBK1 and IKKe act like an OFF switch to limit NLRP3 inflammasome pathway activation.
PubMed Identifier: 34518217
author list: Fischer FA, Mies LFM, Nizami S, Pantazi E, Danielli S, Demarco B, Ohlmeyer M, Lee MSJ, Coban C, Kagan JC, Di Daniel E, Bezbradica JS
published in: Proceedings of the National Academy of Sciences of the United States of America
information resource reference: TBK1 and IKKe act like an OFF switch to limit NLRP3 inflammasome pathway activation. Proc Natl Acad Sci U S A. 2021 09 21; 118(38).
journal title abbreviation: Proc Natl Acad Sci U S A
publication date: 2021-09-21T00:00:00
year: 2021
type: Academic Article
type: Article
type: Document
type: Information Resource

Initiation and Regulation of Antiviral Innate Immunity
end date: 2022-08-31
principal investigator name: KAGAN, JONATHAN C
start date: 2011-03-01
type: Grant
sponsor award id: R56AI093589

Principal Investigator
type: Researcher Role
researcher role of: Kagan, Jonathan
contributes to: Initiation and Regulation of Antiviral Innate Immunity

Authorship 1396026
type: Authorship
author rank in publication: 2
linked author: Kagan, Jonathan
linked information resource: Innate immune detection of lipid oxidation as a threat assessment strategy.

Innate immune detection of lipid oxidation as a threat assessment strategy.
PubMed Identifier: 34548649
author list: Zhivaki D, Kagan JC
published in: Nature reviews. Immunology
information resource reference: Innate immune detection of lipid oxidation as a threat assessment strategy. Nat Rev Immunol. 2022 05; 22(5):322-330.
journal title abbreviation: Nat Rev Immunol
publication date: 2021-09-21T00:00:00
year: 2021
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1405977
type: Authorship
author rank in publication: 4
linked author: Kagan, Jonathan
linked information resource: Emerging roles of peroxisomes in viral infections.

Emerging roles of peroxisomes in viral infections.
PubMed Identifier: 34696946
author list: Ferreira AR, Marques M, Ramos B, Kagan JC, Ribeiro D
published in: Trends in cell biology
information resource reference: Emerging roles of peroxisomes in viral infections. Trends Cell Biol. 2022 02; 32(2):124-139.
journal title abbreviation: Trends Cell Biol
publication date: 2021-10-22T00:00:00
year: 2021
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1413380
type: Authorship
author rank in publication: 3
linked author: Kagan, Jonathan
linked information resource: Evolution-inspired redesign of the LPS receptor caspase-4 into an interleukin-1ß converting enzyme.

Authorship 1414879
type: Authorship
author rank in publication: 3
linked author: Kagan, Jonathan
linked information resource: Heterologous Expression and Assembly of Human TLR Signaling Components in Saccharomyces cerevisiae.

Authorship 1410631
type: Authorship
author rank in publication: 2
linked author: Kagan, Jonathan
linked information resource: Cytosolic detection of phagosomal bacteria-Mechanisms underlying PAMP exodus from the phagosome into the cytosol.

Heterologous Expression and Assembly of Human TLR Signaling Components in Saccharomyces cerevisiae.
PubMed Identifier: 34827735
author list: Coronas-Serna JM, Del Val E, Kagan JC, Molina M, Cid VJ
published in: Biomolecules
information resource reference: Heterologous Expression and Assembly of Human TLR Signaling Components in Saccharomyces cerevisiae. Biomolecules. 2021 Nov 22; 11(11).
journal title abbreviation: Biomolecules
publication date: 2021-11-22T00:00:00
year: 2021
type: Academic Article
type: Article
type: Document
type: Information Resource

Cytosolic detection of phagosomal bacteria-Mechanisms underlying PAMP exodus from the phagosome into the cytosol.
PubMed Identifier: 34738270
author list: Ragland SA, Kagan JC
published in: Molecular microbiology
information resource reference: Cytosolic detection of phagosomal bacteria-Mechanisms underlying PAMP exodus from the phagosome into the cytosol. Mol Microbiol. 2021 12; 116(6):1420-1432.
journal title abbreviation: Mol Microbiol
publication date: 2021-11-22T00:00:00
year: 2021
type: Academic Article
type: Article
type: Document
type: Information Resource

Evolution-inspired redesign of the LPS receptor caspase-4 into an interleukin-1ß converting enzyme.
PubMed Identifier: 34734155
author list: Devant P, Cao A, Kagan JC
published in: Science immunology
information resource reference: Evolution-inspired redesign of the LPS receptor caspase-4 into an interleukin-1ß converting enzyme. Sci Immunol. 2021 08 10; 6(62).
journal title abbreviation: Sci Immunol
publication date: 2021-08-10T00:00:00
year: 2021
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1421682
type: Authorship
author rank in publication: 2
linked author: Kagan, Jonathan
linked information resource: Gasdermin Pore Forming Activities that Promote Inflammation from Living and Dead Cells.

Gasdermin Pore Forming Activities that Promote Inflammation from Living and Dead Cells.
PubMed Identifier: 34973239
author list: Cao A, Kagan JC
published in: Journal of molecular biology
information resource reference: Gasdermin Pore Forming Activities that Promote Inflammation from Living and Dead Cells. J Mol Biol. 2022 02 28; 434(4):167427.
journal title abbreviation: J Mol Biol
publication date: 2021-12-29T00:00:00
year: 2021
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1429612
type: Authorship
author rank in publication: 12
linked author: Kagan, Jonathan
linked information resource: Depletion of the apical endosome in response to viruses and bacterial toxins provides cell-autonomous host defense at mucosal surfaces.

Authorship 1430735
type: Authorship
author rank in publication: 2
linked author: Kagan, Jonathan
linked information resource: The hemolysis of erythrocytes by singlet oxygen generated in the gas phase.

The hemolysis of erythrocytes by singlet oxygen generated in the gas phase.
PubMed Identifier: 2089422
author list: Wang TP, Kagan J, Lee S, Keiderling T
published in: Photochemistry and photobiology
information resource reference: The hemolysis of erythrocytes by singlet oxygen generated in the gas phase. Photochem Photobiol. 1990 Oct; 52(4):753-6.
journal title abbreviation: Photochem Photobiol
publication date: 1990-10-01T00:00:00
year: 1990
type: Academic Article
type: Article
type: Document
type: Information Resource

Depletion of the apical endosome in response to viruses and bacterial toxins provides cell-autonomous host defense at mucosal surfaces.
PubMed Identifier: 35143768
author list: Maeda K, Zachos NC, Orzalli MH, Schmieder SS, Chang D, Bugda Gwilt K, Doucet M, Baetz NW, Lee S, Crawford SE, Estes MK, Kagan JC, Turner JR, Lencer WI
published in: Cell host & microbe
information resource reference: Depletion of the apical endosome in response to viruses and bacterial toxins provides cell-autonomous host defense at mucosal surfaces. Cell Host Microbe. 2022 02 09; 30(2):216-231.e5.
journal title abbreviation: Cell Host Microbe
publication date: 2022-02-09T00:00:00
year: 2022
type: Academic Article
type: Article
type: Document
type: Information Resource

Evavold, Charles
eCommons Login: CLE13
first name: Charles
last name: Evavold
full name: Charles Lee Evavold, Ph.D.
has faculty rank: Instructor
Person ID: 127734
person in primary position: Instructor in Medicine
type: Agent
type: Person
preferred title: Instructor in Medicine

Instructor in Medicine
is primary position: true
position in department: Medicine
position in division: Pulmonary and Critical Care Medicine
sort order: 1
type: Position
HR job title: Instructor in Medicine
position in organization: Massachusetts General Hospital

Authorship 1444790
type: Authorship
author rank in publication: 2
linked author: Kagan, Jonathan
linked information resource: Control of innate immunity by the cGAS-STING pathway.

Authorship 1447839
type: Authorship
author rank in publication: 6
linked author: Kagan, Jonathan
linked information resource: Human Cytomegalovirus vMIA Inhibits MAVS Oligomerization at Peroxisomes in an MFF-Dependent Manner.

Control of innate immunity by the cGAS-STING pathway.
PubMed Identifier: 35485309
author list: Mosallanejad K, Kagan JC
published in: Immunology and cell biology
information resource reference: Control of innate immunity by the cGAS-STING pathway. Immunol Cell Biol. 2022 07; 100(6):409-423.
journal title abbreviation: Immunol Cell Biol
publication date: 2022-05-25T00:00:00
year: 2022
type: Academic Article
type: Article
type: Document
type: Information Resource

Human Cytomegalovirus vMIA Inhibits MAVS Oligomerization at Peroxisomes in an MFF-Dependent Manner.
PubMed Identifier: 35445031
author list: Ferreira AR, Gouveia A, Magalhães AC, Valença I, Marques M, Kagan JC, Ribeiro D
published in: Frontiers in cell and developmental biology
information resource reference: Human Cytomegalovirus vMIA Inhibits MAVS Oligomerization at Peroxisomes in an MFF-Dependent Manner. Front Cell Dev Biol. 2022; 10:871977.
journal title abbreviation: Front Cell Dev Biol
publication date: 2022-04-04T00:00:00
year: 2022
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 307485
type: Authorship
author rank in publication: 2
linked author: Kagan, Jonathan
linked information resource: A cell biological view of Toll-like receptor function: regulation through compartmentalization.

Authorship 309506
type: Authorship
author rank in publication: 8
linked author: Kagan, Jonathan
linked information resource: CD14 controls the LPS-induced endocytosis of Toll-like receptor 4.

Authorship 389521
type: Authorship
author rank in publication: 1
linked author: Kagan, Jonathan
linked information resource: Phosphoinositide-mediated adaptor recruitment controls Toll-like receptor signaling.

Authorship 1458929
type: Authorship
author rank in publication: 2
linked author: Kagan, Jonathan
linked information resource: Diverse Control Mechanisms of the Interleukin-1 Cytokine Family.

Diverse Control Mechanisms of the Interleukin-1 Cytokine Family.
PubMed Identifier: 35832789
author list: Evavold CL, Kagan JC
published in: Frontiers in cell and developmental biology
information resource reference: Diverse Control Mechanisms of the Interleukin-1 Cytokine Family. Front Cell Dev Biol. 2022; 10:910983.
journal title abbreviation: Front Cell Dev Biol
publication date: 2022-06-27T00:00:00
year: 2022
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1488355
type: Authorship
author rank in publication: 3
linked author: Kagan, Jonathan
linked information resource: Lipopolysaccharide detection by the innate immune system may be an uncommon defence strategy used in nature.

Lipopolysaccharide detection by the innate immune system may be an uncommon defence strategy used in nature.
PubMed Identifier: 36196535
author list: Gauthier AE, Rotjan RD, Kagan JC
published in: Open biology
information resource reference: Lipopolysaccharide detection by the innate immune system may be an uncommon defence strategy used in nature. Open Biol. 2022 10; 12(10):220146.
journal title abbreviation: Open Biol
publication date: 2022-10-05T00:00:00
year: 2022
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1509132
type: Authorship
author rank in publication: 9
linked author: Kagan, Jonathan
linked information resource: Glycine inhibits NINJ1 membrane clustering to suppress plasma membrane rupture in cell death.

Glycine inhibits NINJ1 membrane clustering to suppress plasma membrane rupture in cell death.
PubMed Identifier: 36468682
author list: Borges JP, Sætra RSR, Volchuk A, Bugge M, Devant P, Sporsheim B, Kilburn BR, Evavold CL, Kagan JC, Goldenberg NM, Flo TH, Steinberg BE
published in: eLife
information resource reference: Glycine inhibits NINJ1 membrane clustering to suppress plasma membrane rupture in cell death. Elife. 2022 12 05; 11.
journal title abbreviation: Elife
publication date: 2022-12-05T00:00:00
year: 2022
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1512325
type: Authorship
author rank in publication: 1
linked author: Kagan, Jonathan
linked information resource: Excess lipids on endosomes dictates NLRP3 localization and inflammasome activation.

Authorship 1511985
type: Authorship
author rank in publication: 2
linked author: Kagan, Jonathan
linked information resource: Protocol to purify recombinant inflammatory caspases and assess their catalytic activity in vitro.

Excess lipids on endosomes dictates NLRP3 localization and inflammasome activation.
PubMed Identifier: 36596890
author list: Kagan JC
published in: Nature immunology
information resource reference: Excess lipids on endosomes dictates NLRP3 localization and inflammasome activation. Nat Immunol. 2023 01; 24(1):3-4.
journal title abbreviation: Nat Immunol
publication date: 2023-01-01T00:00:00
year: 2023
type: Academic Article
type: Article
type: Document
type: Information Resource

Protocol to purify recombinant inflammatory caspases and assess their catalytic activity in vitro.
PubMed Identifier: 36595884
author list: Devant P, Kagan JC
published in: STAR protocols
information resource reference: Protocol to purify recombinant inflammatory caspases and assess their catalytic activity in vitro. STAR Protoc. 2022 12 16; 3(4):101848.
journal title abbreviation: STAR Protoc
publication date: 2022-11-14T00:00:00
year: 2022
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1516403
type: Authorship
author rank in publication: 9
linked author: Kagan, Jonathan
linked information resource: Species-specific self-DNA detection mechanisms by mammalian cyclic GMP-AMP synthases.

Authorship 1516391
type: Authorship
author rank in publication: 9
linked author: Kagan, Jonathan
linked information resource: Gasdermin D pore-forming activity is redox-sensitive.

Gasdermin D pore-forming activity is redox-sensitive.
PubMed Identifier: 36662620
author list: Devant P, Boršic E, Ngwa EM, Xiao H, Chouchani ET, Thiagarajah JR, Hafner-Bratkovic I, Evavold CL, Kagan JC
published in: Cell reports
information resource reference: Gasdermin D pore-forming activity is redox-sensitive. Cell Rep. 2023 01 31; 42(1):112008.
journal title abbreviation: Cell Rep
publication date: 2023-01-19T00:00:00
year: 2023
type: Academic Article
type: Article
type: Document
type: Information Resource

Species-specific self-DNA detection mechanisms by mammalian cyclic GMP-AMP synthases.
PubMed Identifier: 36662885
author list: Mosallanejad K, Kennedy SN, Bahleda KM, Slavik KM, Zhou W, Govande AA, Hancks DC, Kranzusch PJ, Kagan JC
published in: Science immunology
information resource reference: Species-specific self-DNA detection mechanisms by mammalian cyclic GMP-AMP synthases. Sci Immunol. 2023 01 20; 8(79):eabp9765.
journal title abbreviation: Sci Immunol
publication date: 2023-01-20T00:00:00
year: 2023
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1518542
type: Authorship
author rank in publication: 1
linked author: Kagan, Jonathan
linked information resource: Infection infidelities drive innate immunity.

Infection infidelities drive innate immunity.
PubMed Identifier: 36701444
author list: Kagan JC
published in: Science (New York, N.Y.)
information resource reference: Infection infidelities drive innate immunity. Science. 2023 01 27; 379(6630):333-335.
journal title abbreviation: Science
publication date: 2023-01-26T00:00:00
year: 2023
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1532527
type: Authorship
author rank in publication: 1
linked author: Kagan, Jonathan
linked information resource: Cold Spring Harbor Laboratory 2022: emerging insights and viewpoints in immunology.

Cold Spring Harbor Laboratory 2022: emerging insights and viewpoints in immunology.
PubMed Identifier: 36907684
author list: Kagan JC, Rothenberg EV, Weiss A, Rudensky AY, Smale ST
published in: Trends in immunology
information resource reference: Cold Spring Harbor Laboratory 2022: emerging insights and viewpoints in immunology. Trends Immunol. 2023 04; 44(4):248-255.
journal title abbreviation: Trends Immunol
publication date: 2023-03-11T00:00:00
year: 2023
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1534184
type: Authorship
author rank in publication: 11
linked author: Kagan, Jonathan
linked information resource: ROS-dependent palmitoylation is an obligate licensing modification for GSDMD pore formation.

ROS-dependent palmitoylation is an obligate licensing modification for GSDMD pore formation.
PubMed Identifier: 36945424
author list: Du G, Healy LB, David L, Walker C, Fontana P, Dong Y, Devant P, Puthenveetil R, Ficarro SB, Banerjee A, Kagan JC, Lieberman J, Wu H
published in: bioRxiv : the preprint server for biology
information resource reference: ROS-dependent palmitoylation is an obligate licensing modification for GSDMD pore formation. bioRxiv. 2023 03 07.
journal title abbreviation: bioRxiv
publication date: 2023-03-07T00:00:00
year: 2023
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 189236
type: Authorship
author rank in publication: 5
linked author: Kagan, Jonathan
linked information resource: Selective modulation of TLR4-activated inflammatory responses by altered iron homeostasis in mice.

Authorship 480084
type: Authorship
author rank in publication: 6
linked author: Kagan, Jonathan
linked information resource: Further evidence of an association between behavioral inhibition and anxiety disorders: results from a family study of children from a non-clinical sample.

Precision Vaccines
type: Division
type: Organization

Ragon Institute of MGH, MIT and Harvard
type: Division
type: Organization

Zanoni, Ivan
eCommons Login: IZ13
first name: Ivan
last name: Zanoni
full name: Ivan Zanoni, Ph.D.
has faculty rank: Full Professor
Person ID: 119810
person in primary position: Professor of Pediatrics
type: Agent
type: Person
preferred title: Professor of Pediatrics

Authorship 1571592
type: Authorship
author rank in publication: 2
linked author: Kagan, Jonathan
linked information resource: Inflammasomes as regulators of non-infectious disease.

Authorship 1569377
type: Authorship
author rank in publication: 2
linked author: Kagan, Jonathan
linked information resource: Molecular mechanisms of gasdermin D pore-forming activity.

Authorship 1543999
type: Authorship
author rank in publication: 12
linked author: Kagan, Jonathan
linked information resource: Photochemical and photobiological studies of a furonaphthopyranone as a benzo-spaced psoralen analog in cell-free and cellular DNA.

Authorship 1553064
type: Authorship
author rank in publication: 2
linked author: Kagan, Jonathan
linked information resource: Beyond natural biology: rewiring cellular networks to study innate immunity.

Authorship 1573162
type: Authorship
author rank in publication: 9
linked author: Kagan, Jonathan
linked information resource: Ultrasound-responsive low-dose doxorubicin liposomes trigger mitochondrial DNA release and activate cGAS-STING-mediated antitumour immunity.

Beyond natural biology: rewiring cellular networks to study innate immunity.
PubMed Identifier: 37269786
author list: Landau LM, Kagan JC
published in: Current opinion in immunology
information resource reference: Beyond natural biology: rewiring cellular networks to study innate immunity. Curr Opin Immunol. 2023 08; 83:102349.
journal title abbreviation: Curr Opin Immunol
publication date: 2023-06-01T00:00:00
year: 2023
type: Academic Article
type: Article
type: Document
type: Information Resource

Ultrasound-responsive low-dose doxorubicin liposomes trigger mitochondrial DNA release and activate cGAS-STING-mediated antitumour immunity.
PubMed Identifier: 37391428
author list: Wang C, Zhang R, He J, Yu L, Li X, Zhang J, Li S, Zhang C, Kagan JC, Karp JM, Kuai R
published in: Nature communications
information resource reference: Ultrasound-responsive low-dose doxorubicin liposomes trigger mitochondrial DNA release and activate cGAS-STING-mediated antitumour immunity. Nat Commun. 2023 06 30; 14(1):3877.
journal title abbreviation: Nat Commun
publication date: 2023-06-30T00:00:00
year: 2023
type: Academic Article
type: Article
type: Document
type: Information Resource

Molecular mechanisms of gasdermin D pore-forming activity.
PubMed Identifier: 37277654
author list: Devant P, Kagan JC
published in: Nature immunology
information resource reference: Molecular mechanisms of gasdermin D pore-forming activity. Nat Immunol. 2023 07; 24(7):1064-1075.
journal title abbreviation: Nat Immunol
publication date: 2023-06-05T00:00:00
year: 2023
type: Academic Article
type: Article
type: Document
type: Information Resource

Inflammasomes as regulators of non-infectious disease.
PubMed Identifier: 37506489
author list: Okin D, Kagan JC
published in: Seminars in immunology
information resource reference: Inflammasomes as regulators of non-infectious disease. Semin Immunol. 2023 09; 69:101815.
journal title abbreviation: Semin Immunol
publication date: 2023-07-26T00:00:00
year: 2023
type: Academic Article
type: Article
type: Document
type: Information Resource

Photochemical and photobiological studies of a furonaphthopyranone as a benzo-spaced psoralen analog in cell-free and cellular DNA.
PubMed Identifier: 9230704
author list: Adam W, Mielke K, Saha-Möller CR, Möller M, Stopper H, Hutterer R, Schneider FW, Ballmaier D, Epe B, Gasparro FF, Chen X, Kagan J
published in: Photochemistry and photobiology
information resource reference: Photochemical and photobiological studies of a furonaphthopyranone as a benzo-spaced psoralen analog in cell-free and cellular DNA. Photochem Photobiol. 1997 Jul; 66(1):46-54.
journal title abbreviation: Photochem Photobiol
publication date: 1997-07-01T00:00:00
year: 1997
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 282324
type: Authorship
author rank in publication: 4
linked author: Kagan, Jonathan
linked information resource: Standardization of absolute CD4+ lymphocyte counts across laboratories: an evaluation of the Ortho CytoronAbsolute flow cytometry system on normal donors.

Authorship 1590103
type: Authorship
author rank in publication: 1
linked author: Kagan, Jonathan
linked information resource: Carmichael's insight.

Authorship 1587858
type: Authorship
author rank in publication: 2
linked author: Kagan, Jonathan
linked information resource: Targeting innate immune pathways for cancer immunotherapy.

Authorship 1589107
type: Authorship
author rank in publication: 1
linked author: Kagan, Jonathan
linked information resource: Innate immunity decreases pathogen diversity during infection.

Carmichael's insight.
PubMed Identifier: 3297881
author list: Kagan J
published in: Developmental psychobiology
information resource reference: Carmichael's insight. Dev Psychobiol. 1987 May; 20(3):241-4.
journal title abbreviation: Dev Psychobiol
publication date: 1987-05-01T00:00:00
year: 1987
type: Academic Article
type: Article
type: Document
type: Information Resource

Innate immunity decreases pathogen diversity during infection.
PubMed Identifier: 37729173
author list: Kagan JC
published in: Proceedings of the National Academy of Sciences of the United States of America
information resource reference: Innate immunity decreases pathogen diversity during infection. Proc Natl Acad Sci U S A. 2023 10 03; 120(40):e2314237120.
journal title abbreviation: Proc Natl Acad Sci U S A
publication date: 2023-09-20T00:00:00
year: 2023
type: Academic Article
type: Article
type: Document
type: Information Resource

Targeting innate immune pathways for cancer immunotherapy.
PubMed Identifier: 37703879
author list: Cao LL, Kagan JC
published in: Immunity
information resource reference: Targeting innate immune pathways for cancer immunotherapy. Immunity. 2023 10 10; 56(10):2206-2217.
journal title abbreviation: Immunity
publication date: 2023-09-12T00:00:00
year: 2023
type: Academic Article
type: Article
type: Document
type: Information Resource

Professor of Medicine
is primary position: true
position in department: Medicine
position in division: Gastroenterology
sort order: 1
type: Position
HR job title: Professor of Medicine
position in organization: Beth Israel Deaconess Medical Center

Authorship 1604811
type: Authorship
author rank in publication: 23
linked author: Kagan, Jonathan
linked information resource: Gasdermin D permeabilization of mitochondrial inner and outer membranes accelerates and enhances pyroptosis.

Authorship 1605338
type: Authorship
author rank in publication: 11
linked author: Kagan, Jonathan
linked information resource: mRNAs encoding self-DNA reactive cGAS enhance the immunogenicity of lipid nanoparticle vaccines.

mRNAs encoding self-DNA reactive cGAS enhance the immunogenicity of lipid nanoparticle vaccines.
PubMed Identifier: 37937842
author list: Zhivaki D, Gosselin EA, Sengupta D, Concepcion H, Arinze C, Chow J, Nikiforov A, Komoroski V, MacFarlane C, Sullivan C, Kagan JC
published in: mBio
information resource reference: mRNAs encoding self-DNA reactive cGAS enhance the immunogenicity of lipid nanoparticle vaccines. mBio. 2023 12 19; 14(6):e0250623.
journal title abbreviation: mBio
publication date: 2023-11-08T00:00:00
year: 2023
type: Academic Article
type: Article
type: Document
type: Information Resource

Gasdermin D permeabilization of mitochondrial inner and outer membranes accelerates and enhances pyroptosis.
PubMed Identifier: 37924812
author list: Miao R, Jiang C, Chang WY, Zhang H, An J, Ho F, Chen P, Zhang H, Junqueira C, Amgalan D, Liang FG, Zhang J, Evavold CL, Hafner-Bratkovic I, Zhang Z, Fontana P, Xia S, Waldeck-Weiermair M, Pan Y, Michel T, Bar-Peled L, Wu H, Kagan JC, Kitsis RN, Zhang P, Liu X, Lieberman J
published in: Immunity
information resource reference: Gasdermin D permeabilization of mitochondrial inner and outer membranes accelerates and enhances pyroptosis. Immunity. 2023 11 14; 56(11):2523-2541.e8.
journal title abbreviation: Immunity
publication date: 2023-11-03T00:00:00
year: 2023
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 493600
type: Authorship
author rank in publication: 7
linked author: Kagan, Jonathan
linked information resource: Further evidence of association between behavioral inhibition and social anxiety in children.

Authorship 1608359
type: Authorship
author rank in publication: 7
linked author: Kagan, Jonathan
linked information resource: Structural insights into cytokine cleavage by inflammatory caspase-4.

Authorship 1607296
type: Authorship
author rank in publication: 2
linked author: Kagan, Jonathan
linked information resource: Perception of music by infants.

Perception of music by infants.
PubMed Identifier: 8779711
author list: Zentner MR, Kagan J
published in: Nature
information resource reference: Perception of music by infants. Nature. 1996 Sep 05; 383(6595):29.
journal title abbreviation: Nature
publication date: 1996-09-05T00:00:00
year: 1996
type: Academic Article
type: Article
type: Document
type: Information Resource

Structural insights into cytokine cleavage by inflammatory caspase-4.
PubMed Identifier: 37993712
author list: Devant P, Dong Y, Mintseris J, Ma W, Gygi SP, Wu H, Kagan JC
published in: Nature
information resource reference: Structural insights into cytokine cleavage by inflammatory caspase-4. Nature. 2023 12; 624(7991):451-459.
journal title abbreviation: Nature
publication date: 2023-11-22T00:00:00
year: 2023
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1618431
type: Authorship
author rank in publication: 21
linked author: Kagan, Jonathan
linked information resource: Candida albicans extracellular vesicles trigger type I IFN signalling via cGAS and STING.

Authorship 1618563
type: Authorship
author rank in publication: 7
linked author: Kagan, Jonathan
linked information resource: Publisher Correction: Structural insights into cytokine cleavage by inflammatory caspase-4.

Candida albicans extracellular vesicles trigger type I IFN signalling via cGAS and STING.
PubMed Identifier: 38168615
author list: Brown Harding H, Kwaku GN, Reardon CM, Khan NS, Zamith-Miranda D, Zarnowski R, Tam JM, Bohaen CK, Richey L, Mosallanejad K, Crossen AJ, Reedy JL, Ward RA, Vargas-Blanco DA, Basham KJ, Bhattacharyya RP, Nett JE, Mansour MK, van de Veerdonk FL, Kumar V, Kagan JC, Andes DR, Nosanchuk JD, Vyas JM
published in: Nature microbiology
information resource reference: Candida albicans extracellular vesicles trigger type I IFN signalling via cGAS and STING. Nat Microbiol. 2024 Jan; 9(1):95-107.
journal title abbreviation: Nat Microbiol
publication date: 2024-01-02T00:00:00
year: 2024
type: Academic Article
type: Article
type: Document
type: Information Resource

Publisher Correction: Structural insights into cytokine cleavage by inflammatory caspase-4.
PubMed Identifier: 38172642
author list: Devant P, Dong Y, Mintseris J, Ma W, Gygi SP, Wu H, Kagan JC
published in: Nature
information resource reference: Publisher Correction: Structural insights into cytokine cleavage by inflammatory caspase-4. Nature. 2024 Jan; 625(7995):E17.
journal title abbreviation: Nature
publication date: 2024-01-01T00:00:00
year: 2024
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 552770
type: Authorship
author rank in publication: 1
linked author: Kagan, Jonathan
linked information resource: Defining the subcellular sites of innate immune signal transduction.

Authorship 1636655
type: Authorship
author rank in publication: 22
linked author: Kagan, Jonathan
linked information resource: The palmitoylation of gasdermin D directs its membrane translocation and pore formation during pyroptosis.

Authorship 1638463
type: Authorship
author rank in publication: 6
linked author: Kagan, Jonathan
linked information resource: Limiting the location of a putative human prostate cancer tumor suppressor gene at chromosome 13q14.3.

The palmitoylation of gasdermin D directs its membrane translocation and pore formation during pyroptosis.
PubMed Identifier: 38530158
author list: Balasubramanian A, Hsu AY, Ghimire L, Tahir M, Devant P, Fontana P, Du G, Liu X, Fabin D, Kambara H, Xie X, Liu F, Hasegawa T, Xu R, Yu H, Chen M, Kolakowski S, Trauger S, Larsen MR, Wei W, Wu H, Kagan JC, Lieberman J, Luo HR
published in: Science immunology
information resource reference: The palmitoylation of gasdermin D directs its membrane translocation and pore formation during pyroptosis. Sci Immunol. 2024 04 12; 9(94):eadn1452.
journal title abbreviation: Sci Immunol
publication date: 2024-04-12T00:00:00
year: 2024
type: Academic Article
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Limiting the location of a putative human prostate cancer tumor suppressor gene at chromosome 13q14.3.
PubMed Identifier: 10602517
author list: Yin Z, Spitz MR, Babaian RJ, Strom SS, Troncoso P, Kagan J
published in: Oncogene
information resource reference: Limiting the location of a putative human prostate cancer tumor suppressor gene at chromosome 13q14.3. Oncogene. 1999 Dec 09; 18(52):7576-83.
journal title abbreviation: Oncogene
publication date: 1999-12-09T00:00:00
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type: Academic Article
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Authorship 1641342
type: Authorship
author rank in publication: 19
linked author: Kagan, Jonathan
linked information resource: ROS-dependent S-palmitoylation activates cleaved and intact gasdermin D.

ROS-dependent S-palmitoylation activates cleaved and intact gasdermin D.
PubMed Identifier: 38599239
author list: Du G, Healy LB, David L, Walker C, El-Baba TJ, Lutomski CA, Goh B, Gu B, Pi X, Devant P, Fontana P, Dong Y, Ma X, Miao R, Balasubramanian A, Puthenveetil R, Banerjee A, Luo HR, Kagan JC, Oh SF, Robinson CV, Lieberman J, Wu H
published in: Nature
information resource reference: ROS-dependent S-palmitoylation activates cleaved and intact gasdermin D. Nature. 2024 06; 630(8016):437-446.
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Authorship 236806
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author rank in publication: 7
linked author: Kagan, Jonathan
linked information resource: Can immune markers predict subsequent discordance between immunologic and virologic responses to antiretroviral therapy? Adult AIDS Clinical Trials Group.

Defining the pathways activated by Toll-like Receptors to stimulate immunity
end date: 2031-04-30
principal investigator name: KAGAN, JONATHAN C
start date: 2016-12-13
type: Grant
sponsor award id: R37AI116550

Regulation of immunity by the cGAS-STING pathway
end date: 2027-07-31
principal investigator name: KAGAN, JONATHAN C
start date: 2022-09-19
type: Grant
sponsor award id: R01AI167993

Principal Investigator
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researcher role of: Kagan, Jonathan
contributes to: Regulation of immunity by the cGAS-STING pathway

Principal Investigator
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researcher role of: Kagan, Jonathan
contributes to: Defining the pathways activated by Toll-like Receptors to stimulate immunity

Authorship 1651663
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author rank in publication: 10
linked author: Kagan, Jonathan
linked information resource: Structural transitions enable interleukin-18 maturation and signaling.

Authorship 1648592
type: Authorship
author rank in publication: 2
linked author: Kagan, Jonathan
linked information resource: Strategies of bacterial detection by inflammasomes.

Authorship 1650898
type: Authorship
author rank in publication: 8
linked author: Kagan, Jonathan
linked information resource: Limiting the location of putative human prostate cancer tumor suppressor genes on chromosome 18q.

Authorship 1653631
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author rank in publication: 11
linked author: Kagan, Jonathan
linked information resource: Control of Inflammatory Response by Tissue Microenvironment.

Structural transitions enable interleukin-18 maturation and signaling.
PubMed Identifier: 38733997
author list: Dong Y, Bonin JP, Devant P, Liang Z, Sever AIM, Mintseris J, Aramini JM, Du G, Gygi SP, Kagan JC, Kay LE, Wu H
published in: Immunity
information resource reference: Structural transitions enable interleukin-18 maturation and signaling. Immunity. 2024 07 09; 57(7):1533-1548.e10.
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Control of Inflammatory Response by Tissue Microenvironment.
PubMed Identifier: 38798655
author list: Wu Z, Pope SD, Ahmed NS, Leung DL, Hajjar S, Yue Q, Anand DM, Kopp EB, Okin D, Ma W, Kagan JC, Hargreaves DC, Medzhitov R, Zhou X
published in: bioRxiv : the preprint server for biology
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Strategies of bacterial detection by inflammasomes.
PubMed Identifier: 38636521
author list: Jastrab JB, Kagan JC
published in: Cell chemical biology
information resource reference: Strategies of bacterial detection by inflammasomes. Cell Chem Biol. 2024 May 16; 31(5):835-850.
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publication date: 2024-04-17T00:00:00
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type: Academic Article
type: Article
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Limiting the location of putative human prostate cancer tumor suppressor genes on chromosome 18q.
PubMed Identifier: 11402322
author list: Yin Z, Babaian RJ, Troncoso P, Strom SS, Spitz MR, Caudell JJ, Stein JD, Kagan J
published in: Oncogene
information resource reference: Limiting the location of putative human prostate cancer tumor suppressor genes on chromosome 18q. Oncogene. 2001 Apr 26; 20(18):2273-80.
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publication date: 2001-04-26T00:00:00
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Authorship 1657993
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author rank in publication: 12
linked author: Kagan, Jonathan
linked information resource: pLxIS-containing domains are biochemically flexible regulators of interferons and metabolism.

Authorship 1662277
type: Authorship
author rank in publication: 15
linked author: Kagan, Jonathan
linked information resource: Correction of age-associated defects in dendritic cells enables CD4+ T cells to eradicate tumors.

Authorship 1662454
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author rank in publication: 2
linked author: Kagan, Jonathan
linked information resource: Waking the sleeping giant: Single-stranded DNA binds Schlafen 11 to initiate innate immune responses.

pLxIS-containing domains are biochemically flexible regulators of interferons and metabolism.
PubMed Identifier: 38925114
author list: Landau LM, Chaudhary N, Tien YC, Rogozinska M, Joshi S, Yao C, Crowley J, Hullahalli K, Campbell IW, Waldor MK, Haigis M, Kagan JC
published in: Molecular cell
information resource reference: pLxIS-containing domains are biochemically flexible regulators of interferons and metabolism. Mol Cell. 2024 Jul 11; 84(13):2436-2454.e10.
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Waking the sleeping giant: Single-stranded DNA binds Schlafen 11 to initiate innate immune responses.
PubMed Identifier: 38875318
author list: Ragland SA, Kagan JC
published in: Science immunology
information resource reference: Waking the sleeping giant: Single-stranded DNA binds Schlafen 11 to initiate innate immune responses. Sci Immunol. 2024 06 14; 9(96):eadp4474.
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publication date: 2024-06-14T00:00:00
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Correction of age-associated defects in dendritic cells enables CD4+ T cells to eradicate tumors.
PubMed Identifier: 38870946
author list: Zhivaki D, Kennedy SN, Park J, Boriello F, Devant P, Cao A, Bahleda KM, Murphy S, McCabe C, Evavold CL, Chapman KL, Zanoni I, Ashenberg O, Xavier RJ, Kagan JC
published in: Cell
information resource reference: Correction of age-associated defects in dendritic cells enables CD4+ T cells to eradicate tumors. Cell. 2024 Jul 25; 187(15):3888-3903.e18.
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publication date: 2024-06-12T00:00:00
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Authorship 1663958
type: Authorship
author rank in publication: 8
linked author: Kagan, Jonathan
linked information resource: Molecular definition of the endogenous Toll-like receptor signalling pathways.

Molecular definition of the endogenous Toll-like receptor signalling pathways.
PubMed Identifier: 38961291
author list: Fisch D, Zhang T, Sun H, Ma W, Tan Y, Gygi SP, Higgins DE, Kagan JC
published in: Nature
information resource reference: Molecular definition of the endogenous Toll-like receptor signalling pathways. Nature. 2024 07; 631(8021):635-644.
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publication date: 2024-07-03T00:00:00
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Instructor in Medicine
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HR job title: Instructor in Medicine
position in organization: Massachusetts General Hospital

Professor of Pediatrics
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position in department: Pediatrics
position in division: Hematology/Oncology
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HR job title: Professor of Pediatrics
position in organization: Massachusetts Eye and Ear Infirmary

Authorship 446974
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author rank in publication: 6
linked author: Kagan, Jonathan
linked information resource: Startle potentiation by threat of aversive stimuli and darkness in adolescents: a multi-site study.

Authorship 646106
type: Authorship
author rank in publication: 2
linked author: Kagan, Jonathan
linked information resource: Intracellular pathogen detection by RIG-I-like receptors.

Authorship 634806
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author rank in publication: 3
linked author: Kagan, Jonathan
linked information resource: Adolescent social anxiety as an outcome of inhibited temperament in childhood.

Authorship 664563
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author rank in publication: 2
linked author: Kagan, Jonathan
linked information resource: Peroxisomes and the antiviral responses of mammalian cells.

Authorship 651190
type: Authorship
author rank in publication: 1
linked author: Kagan, Jonathan
linked information resource: NLRP3 inflammasome activation: CD36 serves double duty.

Authorship 643190
type: Authorship
author rank in publication: 1
linked author: Kagan, Jonathan
linked information resource: Recognition for an innate explorer.

Authorship 647702
type: Authorship
author rank in publication: 13
linked author: Kagan, Jonathan
linked information resource: The unfolded protein response element IRE1a senses bacterial proteins invading the ER to activate RIG-I and innate immune signaling.

The unfolded protein response element IRE1a senses bacterial proteins invading the ER to activate RIG-I and innate immune signaling.
PubMed Identifier: 23684307
author list: Cho JA, Lee AH, Platzer B, Cross BCS, Gardner BM, De Luca H, Luong P, Harding HP, Glimcher LH, Walter P, Fiebiger E, Ron D, Kagan JC, Lencer WI
published in: Cell host & microbe
information resource reference: The unfolded protein response element IRE1a senses bacterial proteins invading the ER to activate RIG-I and innate immune signaling. Cell Host Microbe. 2013 May 15; 13(5):558-569.
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Intracellular pathogen detection by RIG-I-like receptors.
PubMed Identifier: 23611287
author list: Dixit E, Kagan JC
published in: Advances in immunology
information resource reference: Intracellular pathogen detection by RIG-I-like receptors. Adv Immunol. 2013; 117:99-125.
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publication date: 2013-01-01T00:00:00
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type: Academic Article
type: Article
type: Document
type: Information Resource

NLRP3 inflammasome activation: CD36 serves double duty.
PubMed Identifier: 23867926
author list: Kagan JC, Horng T
published in: Nature immunology
information resource reference: NLRP3 inflammasome activation: CD36 serves double duty. Nat Immunol. 2013 Aug; 14(8):772-4.
journal title abbreviation: Nat Immunol
publication date: 2013-08-01T00:00:00
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type: Academic Article
type: Article
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Peroxisomes and the antiviral responses of mammalian cells.
PubMed Identifier: 23821143
author list: Odendall C, Kagan JC
published in: Sub-cellular biochemistry
information resource reference: Peroxisomes and the antiviral responses of mammalian cells. Subcell Biochem. 2013; 69:67-75.
journal title abbreviation: Subcell Biochem
publication date: 2013-01-01T00:00:00
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type: Academic Article
type: Article
type: Document
type: Information Resource

Recognition for an innate explorer.
PubMed Identifier: 23870114
author list: Kagan JC
published in: Cell
information resource reference: Recognition for an innate explorer. Cell. 2013 Jul 18; 154(2):261-4.
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publication date: 2013-07-18T00:00:00
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type: Information Resource

Authorship 1702153
type: Authorship
author rank in publication: 7
linked author: Kagan, Jonathan
linked information resource: LPS binding caspase activation and recruitment domains (CARDs) are bipartite lipid binding modules.

LPS binding caspase activation and recruitment domains (CARDs) are bipartite lipid binding modules.
PubMed Identifier: 39416091
author list: Cao AB, Devant P, Wang C, Sun M, Kennedy SN, Ruan J, Kagan JC
published in: bioRxiv : the preprint server for biology
information resource reference: LPS binding caspase activation and recruitment domains (CARDs) are bipartite lipid binding modules. bioRxiv. 2024 Oct 11.
journal title abbreviation: bioRxiv
publication date: 2024-10-11T00:00:00
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Authorship 1708691
type: Authorship
author rank in publication: 14
linked author: Kagan, Jonathan
linked information resource: A pan-family screen of nuclear receptors in immunocytes reveals ligand-dependent inflammasome control.

A pan-family screen of nuclear receptors in immunocytes reveals ligand-dependent inflammasome control.
PubMed Identifier: 39571575
author list: Wang Y, Zhang Y, Kim K, Han J, Okin D, Jiang Z, Yang L, Subramaniam A, Means TK, Nestlé FO, Fitzgerald KA, Randolph GJ, Lesser CF, Kagan JC, Mathis D, Benoist C
published in: Immunity
information resource reference: A pan-family screen of nuclear receptors in immunocytes reveals ligand-dependent inflammasome control. Immunity. 2024 12 10; 57(12):2737-2754.e12.
journal title abbreviation: Immunity
publication date: 2024-11-20T00:00:00
year: 2024
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Authorship 1710674
type: Authorship
author rank in publication: 18
linked author: Kagan, Jonathan
linked information resource: Pyroptotic cell corpses are crowned with F-actin-rich filopodia that engage CLEC9A signaling in incoming dendritic cells.

Pyroptotic cell corpses are crowned with F-actin-rich filopodia that engage CLEC9A signaling in incoming dendritic cells.
PubMed Identifier: 39633178
author list: Holley CL, Monteleone M, Fisch D, Libert AES, Ju RJ, Choi JH, Condon ND, Emming S, Crawford J, Lawrence GMEP, Coombs JR, Lefevre JG, Bajracharya R, Lahoud MH, Yap AS, Hamilton N, Stehbens SJ, Kagan JC, Ariotti N, Burgener SS, Schroder K
published in: Nature immunology
information resource reference: Pyroptotic cell corpses are crowned with F-actin-rich filopodia that engage CLEC9A signaling in incoming dendritic cells. Nat Immunol. 2025 Jan; 26(1):42-52.
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publication date: 2024-12-04T00:00:00
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Authorship 676876
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author rank in publication: 1
linked author: Kagan, Jonathan
linked information resource: Immunology. Sensing endotoxins from within.

Immunology. Sensing endotoxins from within.
PubMed Identifier: 24031006
author list: Kagan JC
published in: Science (New York, N.Y.)
information resource reference: Immunology. Sensing endotoxins from within. Science. 2013 Sep 13; 341(6151):1184-5.
journal title abbreviation: Science
publication date: 2013-09-13T00:00:00
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Authorship 248077
type: Authorship
author rank in publication: 1
linked author: Kagan, Jonathan
linked information resource: "Complementing" toll signaling.

Authorship 332040
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author rank in publication: 1
linked author: Kagan, Jonathan
linked information resource: Phagosome as the organelle linking innate and adaptive immunity.

Authorship 1729569
type: Authorship
author rank in publication: 2
linked author: Kagan, Jonathan
linked information resource: ARIES domains: functional signaling units of type I interferon responses.

ARIES domains: functional signaling units of type I interferon responses.
PubMed Identifier: 39964808
author list: Landau LM, Kagan JC
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information resource reference: ARIES domains: functional signaling units of type I interferon responses. FEBS J. 2025 Nov; 292(22):5888-5898.
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publication date: 2025-02-18T00:00:00
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Authorship 1748681
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author rank in publication: 8
linked author: Kagan, Jonathan
linked information resource: LPS binding caspase activation and recruitment domains (CARDs) are bipartite lipid binding modules.

LPS binding caspase activation and recruitment domains (CARDs) are bipartite lipid binding modules.
PubMed Identifier: 40053584
author list: Cao AB, Devant P, Wang C, Sun M, Kennedy SN, Ma W, Ruan J, Kagan JC
published in: Science advances
information resource reference: LPS binding caspase activation and recruitment domains (CARDs) are bipartite lipid binding modules. Sci Adv. 2025 Mar 07; 11(10):eadt9027.
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Authorship 257174
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author rank in publication: 7
linked author: Kagan, Jonathan
linked information resource: Regulation of lipopolysaccharide-induced translation of tumor necrosis factor-alpha by the toll-like receptor 4 adaptor protein TRAM.

Authorship 393411
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author rank in publication: 5
linked author: Kagan, Jonathan
linked information resource: https://connects.catalyst.harvard.edu/Profiles/profile/881155

Authorship 293263
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author rank in publication: 1
linked author: Kagan, Jonathan
linked information resource: Legionella subvert the functions of Rab1 and Sec22b to create a replicative organelle.

Regulation of inflammatory responses by pH-dependent transcriptional condensates.
PubMed Identifier: 40680734
author list: Wu Z, Pope SD, Ahmed NS, Leung DL, Hong Y, Hajjar S, Krabak C, Zhong Z, Raghunathan K, Yue Q, Anand DM, Kopp EB, Okin D, Ma W, Zanoni I, Kagan JC, Thiagarajah JR, Hargreaves DC, Medzhitov R, Zhou X
published in: Cell
information resource reference: Regulation of inflammatory responses by pH-dependent transcriptional condensates. Cell. 2025 Oct 02; 188(20):5632-5652.e25.
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Authorship 709755
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author rank in publication: 7
linked author: Kagan, Jonathan
linked information resource: A 3-year follow-up of children with and without behavioral inhibition.

Authorship 717208
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author rank in publication: 5
linked author: Kagan, Jonathan
linked information resource: A bicistronic MAVS transcript highlights a class of truncated variants in antiviral immunity.

Authorship 724169
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author rank in publication: 9
linked author: Kagan, Jonathan
linked information resource: A promiscuous lipid-binding protein diversifies the subcellular sites of toll-like receptor signal transduction.

Authorship 725166
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author rank in publication: 2
linked author: Kagan, Jonathan
linked information resource: Finding a needle in a haystack of needles - a productive hunt for interferon stimulated genes with antiviral activity.

Finding a needle in a haystack of needles - a productive hunt for interferon stimulated genes with antiviral activity.
PubMed Identifier: 24418815
author list: Franz KM, Kagan JC
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information resource reference: Finding a needle in a haystack of needles - a productive hunt for interferon stimulated genes with antiviral activity. Immunol Cell Biol. 2014 Mar; 92(3):205-7.
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A promiscuous lipid-binding protein diversifies the subcellular sites of toll-like receptor signal transduction.
PubMed Identifier: 24529375
author list: Bonham KS, Orzalli MH, Hayashi K, Wolf AI, Glanemann C, Weninger W, Iwasaki A, Knipe DM, Kagan JC
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information resource reference: A promiscuous lipid-binding protein diversifies the subcellular sites of toll-like receptor signal transduction. Cell. 2014 Feb 13; 156(4):705-16.
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A bicistronic MAVS transcript highlights a class of truncated variants in antiviral immunity.
PubMed Identifier: 24529381
author list: Brubaker SW, Gauthier AE, Mills EW, Ingolia NT, Kagan JC
published in: Cell
information resource reference: A bicistronic MAVS transcript highlights a class of truncated variants in antiviral immunity. Cell. 2014 Feb 13; 156(4):800-11.
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Authorship 731199
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linked information resource: Endosomes as platforms for NOD-like receptor signaling.

Endosomes as platforms for NOD-like receptor signaling.
PubMed Identifier: 24832447
author list: Bonham KS, Kagan JC
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information resource reference: Endosomes as platforms for NOD-like receptor signaling. Cell Host Microbe. 2014 May 14; 15(5):523-5.
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Regulation of innate immunity by the pathogen Staphylococcus aureus
end date: 2031-01-31
principal investigator name: KAGAN, JONATHAN C
start date: 2026-02-19
type: Grant
sponsor award id: R01AI184490

Principal Investigator
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researcher role of: Kagan, Jonathan
contributes to: Regulation of innate immunity by the pathogen Staphylococcus aureus

Authorship 732703
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linked author: Kagan, Jonathan
linked information resource: A cross-disciplinary perspective on the innate immune responses to bacterial lipopolysaccharide.

A cross-disciplinary perspective on the innate immune responses to bacterial lipopolysaccharide.
PubMed Identifier: 24766885
author list: Tan Y, Kagan JC
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information resource reference: A cross-disciplinary perspective on the innate immune responses to bacterial lipopolysaccharide. Mol Cell. 2014 Apr 24; 54(2):212-23.
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Authorship 1774220
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author rank in publication: 5
linked author: Kagan, Jonathan
linked information resource: Guideline for flow cytometric immunophenotyping: a report from the National Institute of Allergy and Infectious Diseases, Division of AIDS.

Authorship 1780056
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author rank in publication: 16
linked author: Kagan, Jonathan
linked information resource: Regulation of inflammatory responses by pH-dependent transcriptional condensates.

Member of the Faculty of Medicine
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Colonna, Marco
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Authorship 1785815
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linked information resource: Homozygous deletions at 8p22 and 8p21 in prostate cancer implicate these regions as the sites for candidate tumor suppressor genes.

Authorship 1785930
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author rank in publication: 2
linked author: Kagan, Jonathan
linked information resource: Method to distinguish between the MMAC1/PTEN gene and its pseudogene in RT-PCR analysis of point mutations.

Authorship 1785714
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author rank in publication: 2
linked author: Kagan, Jonathan
linked information resource: Involvement of the TCL5 gene on human chromosome 1 in T-cell leukemia and melanoma.

Authorship 1786151
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author rank in publication: 5
linked author: Kagan, Jonathan
linked information resource: Inactivation of MMAC1 in bladder transitional-cell carcinoma cell lines and specimens.

Authorship 1786004
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author rank in publication: 1
linked author: Kagan, Jonathan
linked information resource: Cluster of allele losses within a 2.5 cM region of chromosome 10 in high-grade invasive bladder cancer.

Authorship 1786002
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author rank in publication: 10
linked author: Kagan, Jonathan
linked information resource: Epidemiologic determinants of clinically relevant prostate cancer.

Authorship 1786015
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author rank in publication: 3
linked author: Kagan, Jonathan
linked information resource: Advances in the diagnosis of acute leukemia.

Authorship 1786081
type: Authorship
author rank in publication: 6
linked author: Kagan, Jonathan
linked information resource: Localization of chromosome 8p regions involved in early tumorigenesis of oral and laryngeal squamous carcinoma.

Authorship 1786556
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author rank in publication: 3
linked author: Kagan, Jonathan
linked information resource: The human urokinase-plasminogen activator gene (PLAU) is located on chromosome 10q24 centromeric to the HOX11 gene.

Authorship 1786550
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author rank in publication: 3
linked author: Kagan, Jonathan
linked information resource: The chromosome 11 region flanking the t(11;14) breakpoint in human T-ALL is deleted in Wilms' tumor hybrids.

Authorship 1786761
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author rank in publication: 3
linked author: Kagan, Jonathan
linked information resource: Increasing value and reducing waste in biomedical research regulation and management.

Authorship 1789268
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author rank in publication: 1
linked author: Kagan, Jonathan
linked information resource: Joining of recombination signals on the der 14q- chromosome in T-cell acute leukemia with t(10;14) chromosome translocation.

Authorship 1788820
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author rank in publication: 1
linked author: Kagan, Jonathan
linked information resource: Detection of minimal residual disease in leukemic patients with the t(10;14)(q24;q11) chromosomal translocation.

Authorship 1789269
type: Authorship
author rank in publication: 1
linked author: Kagan, Jonathan
linked information resource: Alpha-chain locus of the T-cell antigen receptor is involved in the t(10;14) chromosome translocation of T-cell acute lymphocytic leukemia.

Authorship 1789999
type: Authorship
author rank in publication: 1
linked author: Kagan, Jonathan
linked information resource: Strategy management in collaborative clinical research partnerships.

Authorship 1794391
type: Authorship
author rank in publication: 4
linked author: Kagan, Jonathan
linked information resource: MAVS oligomerization drives a faster and more efficient antiviral signaling activation at peroxisomes compared to mitochondria.

Authorship 1800128
type: Authorship
author rank in publication: 9
linked author: Kagan, Jonathan
linked information resource: A randomized evaluation of on-site monitoring nested in a multinational randomized trial.

Authorship 1801631
type: Authorship
author rank in publication: 1
linked author: Kagan, Jonathan
linked information resource: Molecular biology of lymphoid malignancies.

Authorship 1806465
type: Authorship
author rank in publication: 1
linked author: Kagan, Jonathan
linked information resource: Molecular biology of chromosomal aberrations in leukemia/lymphoma.

Authorship 1805080
type: Authorship
author rank in publication: 1
linked author: Kagan, Jonathan
linked information resource: Clustering of breakpoints on chromosome 10 in acute T-cell leukemias with the t(10;14) chromosome translocation.

Authorship 1808012
type: Authorship
author rank in publication: 3
linked author: Kagan, Jonathan
linked information resource: Genotypic alterations in benign and malignant salivary gland tumors: histogenetic and clinical implications.

Authorship 1812275
type: Authorship
author rank in publication: 7
linked author: Kagan, Jonathan
linked information resource: Towards a molecular and structural definition of cell death.

Authorship 1815345
type: Authorship
author rank in publication: 2
linked author: Kagan, Jonathan
linked information resource: Oxidized phospholipid damage signals as modulators of immunity.

Authorship 1826777
type: Authorship
author rank in publication: 20
linked author: Kagan, Jonathan
linked information resource: An NLRP3-stimulatory adjuvant improves the immunogenicity of influenza virus vaccines in mice and non-human primates.

Authorship 1852772
type: Authorship
author rank in publication: 3
linked author: Kagan, Jonathan
linked information resource: NLRP11 promotes non-canonical inflammasome activation in human macrophages by enhancing caspase-4 recognition of cytosolic lipopolysaccharide.

Molecular biology of lymphoid malignancies.
PubMed Identifier: 2049325
author list: Kagan J, Croce CM
published in: Annals of oncology : official journal of the European Society for Medical Oncology
information resource reference: Molecular biology of lymphoid malignancies. Ann Oncol. 1991 Feb; 2 Suppl 2:9-21.
journal title abbreviation: Ann Oncol
publication date: 1991-02-01T00:00:00
year: 1991
type: Academic Article
type: Article
type: Document
type: Information Resource

Alpha-chain locus of the T-cell antigen receptor is involved in the t(10;14) chromosome translocation of T-cell acute lymphocytic leukemia.
PubMed Identifier: 2885838
author list: Kagan J, Finan J, Letofsky J, Besa EC, Nowell PC, Croce CM
published in: Proceedings of the National Academy of Sciences of the United States of America
information resource reference: Alpha-chain locus of the T-cell antigen receptor is involved in the t(10;14) chromosome translocation of T-cell acute lymphocytic leukemia. Proc Natl Acad Sci U S A. 1987 Jul; 84(13):4543-6.
journal title abbreviation: Proc Natl Acad Sci U S A
publication date: 1987-07-01T00:00:00
year: 1987
type: Academic Article
type: Article
type: Document
type: Information Resource

Detection of minimal residual disease in leukemic patients with the t(10;14)(q24;q11) chromosomal translocation.
PubMed Identifier: 2386934
author list: Kagan J, Finger LR, Besa E, Croce CM
published in: Cancer research
information resource reference: Detection of minimal residual disease in leukemic patients with the t(10;14)(q24;q11) chromosomal translocation. Cancer Res. 1990 Sep 01; 50(17):5240-4.
journal title abbreviation: Cancer Res
publication date: 1990-09-01T00:00:00
year: 1990
type: Academic Article
type: Article
type: Document
type: Information Resource

The chromosome 11 region flanking the t(11;14) breakpoint in human T-ALL is deleted in Wilms' tumor hybrids.
PubMed Identifier: 2558334
author list: Finver SN, Martiniere C, Kagan J, Cavenee W, Croce CM
published in: Oncogene research
information resource reference: The chromosome 11 region flanking the t(11;14) breakpoint in human T-ALL is deleted in Wilms' tumor hybrids. Oncogene Res. 1989; 5(2):143-8.
journal title abbreviation: Oncogene Res
publication date: 1989-01-01T00:00:00
year: 1989
type: Academic Article
type: Article
type: Document
type: Information Resource

Joining of recombination signals on the der 14q- chromosome in T-cell acute leukemia with t(10;14) chromosome translocation.
PubMed Identifier: 8261443
author list: Kagan J, Joe YS, Freireich EJ
published in: Cancer research
information resource reference: Joining of recombination signals on the der 14q- chromosome in T-cell acute leukemia with t(10;14) chromosome translocation. Cancer Res. 1994 Jan 01; 54(1):226-30.
journal title abbreviation: Cancer Res
publication date: 1994-01-01T00:00:00
year: 1994
type: Academic Article
type: Article
type: Document
type: Information Resource

Homozygous deletions at 8p22 and 8p21 in prostate cancer implicate these regions as the sites for candidate tumor suppressor genes.
PubMed Identifier: 7478532
author list: Kagan J, Stein J, Babaian RJ, Joe YS, Pisters LL, Glassman AB, von Eschenbach AC, Troncoso P
published in: Oncogene
information resource reference: Homozygous deletions at 8p22 and 8p21 in prostate cancer implicate these regions as the sites for candidate tumor suppressor genes. Oncogene. 1995 Nov 16; 11(10):2121-6.
journal title abbreviation: Oncogene
publication date: 1995-11-16T00:00:00
year: 1995
type: Academic Article
type: Article
type: Document
type: Information Resource

The human urokinase-plasminogen activator gene (PLAU) is located on chromosome 10q24 centromeric to the HOX11 gene.
PubMed Identifier: 8098010
author list: Stein PM, Stass SA, Kagan J
published in: Genomics
information resource reference: The human urokinase-plasminogen activator gene (PLAU) is located on chromosome 10q24 centromeric to the HOX11 gene. Genomics. 1993 Apr; 16(1):301-2.
journal title abbreviation: Genomics
publication date: 1993-04-01T00:00:00
year: 1993
type: Academic Article
type: Article
type: Document
type: Information Resource

Clustering of breakpoints on chromosome 10 in acute T-cell leukemias with the t(10;14) chromosome translocation.
PubMed Identifier: 2542965
author list: Kagan J, Finger LR, Letofsky J, Finan J, Nowell PC, Croce CM
published in: Proceedings of the National Academy of Sciences of the United States of America
information resource reference: Clustering of breakpoints on chromosome 10 in acute T-cell leukemias with the t(10;14) chromosome translocation. Proc Natl Acad Sci U S A. 1989 Jun; 86(11):4161-5.
journal title abbreviation: Proc Natl Acad Sci U S A
publication date: 1989-06-01T00:00:00
year: 1989
type: Academic Article
type: Article
type: Document
type: Information Resource

Involvement of the TCL5 gene on human chromosome 1 in T-cell leukemia and melanoma.
PubMed Identifier: 2740341
author list: Finger LR, Kagan J, Christopher G, Kurtzberg J, Hershfield MS, Nowell PC, Croce CM
published in: Proceedings of the National Academy of Sciences of the United States of America
information resource reference: Involvement of the TCL5 gene on human chromosome 1 in T-cell leukemia and melanoma. Proc Natl Acad Sci U S A. 1989 Jul; 86(13):5039-43.
journal title abbreviation: Proc Natl Acad Sci U S A
publication date: 1989-07-01T00:00:00
year: 1989
type: Academic Article
type: Article
type: Document
type: Information Resource

Molecular biology of chromosomal aberrations in leukemia/lymphoma.
PubMed Identifier: 8244909
author list: Kagan J
published in: Hematologic pathology
information resource reference: Molecular biology of chromosomal aberrations in leukemia/lymphoma. Hematol Pathol. 1993; 7(3):159-201.
journal title abbreviation: Hematol Pathol
publication date: 1993-01-01T00:00:00
year: 1993
type: Academic Article
type: Article
type: Document
type: Information Resource

Inactivation of MMAC1 in bladder transitional-cell carcinoma cell lines and specimens.
PubMed Identifier: 11108659
author list: Liu J, Babaian DC, Liebert M, Steck PA, Kagan J
published in: Molecular carcinogenesis
information resource reference: Inactivation of MMAC1 in bladder transitional-cell carcinoma cell lines and specimens. Mol Carcinog. 2000 Nov; 29(3):143-50.
journal title abbreviation: Mol Carcinog
publication date: 2000-11-01T00:00:00
year: 2000
type: Academic Article
type: Article
type: Document
type: Information Resource

Advances in the diagnosis of acute leukemia.
PubMed Identifier: 8449854
author list: Hirsch-Ginsberg C, Huh YO, Kagan J, Liang JC, Stass SA
published in: Hematology/oncology clinics of North America
information resource reference: Advances in the diagnosis of acute leukemia. Hematol Oncol Clin North Am. 1993 Feb; 7(1):1-46.
journal title abbreviation: Hematol Oncol Clin North Am
publication date: 1993-02-01T00:00:00
year: 1993
type: Academic Article
type: Article
type: Document
type: Information Resource

Epidemiologic determinants of clinically relevant prostate cancer.
PubMed Identifier: 10861502
author list: Spitz MR, Strom SS, Yamamura Y, Troncoso P, Babaian RJ, Scardino PT, Wheeler T, Amos CI, von Eschenbach A, Kagan J
published in: International journal of cancer
information resource reference: Epidemiologic determinants of clinically relevant prostate cancer. Int J Cancer. 2000 May 20; 89(3):259-64.
journal title abbreviation: Int J Cancer
publication date: 2000-05-20T00:00:00
year: 2000
type: Academic Article
type: Article
type: Document
type: Information Resource

Method to distinguish between the MMAC1/PTEN gene and its pseudogene in RT-PCR analysis of point mutations.
PubMed Identifier: 9894586
author list: Liu J, Kagan J
published in: BioTechniques
information resource reference: Method to distinguish between the MMAC1/PTEN gene and its pseudogene in RT-PCR analysis of point mutations. Biotechniques. 1999 Jan; 26(1):19-22, 24.
journal title abbreviation: Biotechniques
publication date: 1999-01-01T00:00:00
year: 1999
type: Academic Article
type: Article
type: Document
type: Information Resource

Cluster of allele losses within a 2.5 cM region of chromosome 10 in high-grade invasive bladder cancer.
PubMed Identifier: 9484782
author list: Kagan J, Liu J, Stein JD, Wagner SS, Babkowski R, Grossman BH, Katz RL
published in: Oncogene
information resource reference: Cluster of allele losses within a 2.5 cM region of chromosome 10 in high-grade invasive bladder cancer. Oncogene. 1998 Feb 19; 16(7):909-13.
journal title abbreviation: Oncogene
publication date: 1998-02-19T00:00:00
year: 1998
type: Academic Article
type: Article
type: Document
type: Information Resource

Genotypic alterations in benign and malignant salivary gland tumors: histogenetic and clinical implications.
PubMed Identifier: 9199647
author list: el-Naggar AK, Hurr K, Kagan J, Gillenwater A, Callender D, Luna MA, Batsakis JG
published in: The American journal of surgical pathology
information resource reference: Genotypic alterations in benign and malignant salivary gland tumors: histogenetic and clinical implications. Am J Surg Pathol. 1997 Jun; 21(6):691-7.
journal title abbreviation: Am J Surg Pathol
publication date: 1997-06-01T00:00:00
year: 1997
type: Academic Article
type: Article
type: Document
type: Information Resource

Localization of chromosome 8p regions involved in early tumorigenesis of oral and laryngeal squamous carcinoma.
PubMed Identifier: 9662330
author list: El-Naggar AK, Coombes MM, Batsakis JG, Hong WK, Goepfert H, Kagan J
published in: Oncogene
information resource reference: Localization of chromosome 8p regions involved in early tumorigenesis of oral and laryngeal squamous carcinoma. Oncogene. 1998 Jun 11; 16(23):2983-7.
journal title abbreviation: Oncogene
publication date: 1998-06-11T00:00:00
year: 1998
type: Academic Article
type: Article
type: Document
type: Information Resource

An NLRP3-stimulatory adjuvant improves the immunogenicity of influenza virus vaccines in mice and non-human primates.
PubMed Identifier: 40919810
author list: Finn K, Chow J, Zhivaki D, Sengupta D, Concepcion H, Komoroski V, MacFarlane C, Coblentz PD, Chokshi M, Matissek S, Gosselin E, Alkekhia D, Nikiforov A, Lamberti N, Iheanyichukwu V, Kelly C, Arinze C, Cornforth A, Elloul S, Kagan JC
published in: mBio
information resource reference: An NLRP3-stimulatory adjuvant improves the immunogenicity of influenza virus vaccines in mice and non-human primates. mBio. 2025 Oct 08; 16(10):e0234325.
journal title abbreviation: mBio
publication date: 2025-09-08T00:00:00
year: 2025
type: Academic Article
type: Article
type: Document
type: Information Resource

Increasing value and reducing waste in biomedical research regulation and management.
PubMed Identifier: 24411646
author list: Al-Shahi Salman R, Beller E, Kagan J, Hemminki E, Phillips RS, Savulescu J, Macleod M, Wisely J, Chalmers I
published in: Lancet (London, England)
information resource reference: Increasing value and reducing waste in biomedical research regulation and management. Lancet. 2014 Jan 11; 383(9912):176-85.
journal title abbreviation: Lancet
publication date: 2014-01-08T00:00:00
year: 2014
type: Academic Article
type: Article
type: Document
type: Information Resource

A randomized evaluation of on-site monitoring nested in a multinational randomized trial.
PubMed Identifier: 31647325
author list: Wyman Engen N, Huppler Hullsiek K, Belloso WH, Finley E, Hudson F, Denning E, Carey C, Pearson M, Kagan J
published in: Clinical trials (London, England)
information resource reference: A randomized evaluation of on-site monitoring nested in a multinational randomized trial. Clin Trials. 2020 02; 17(1):3-14.
journal title abbreviation: Clin Trials
publication date: 2019-10-24T00:00:00
year: 2019
type: Academic Article
type: Article
type: Document
type: Information Resource

Oxidized phospholipid damage signals as modulators of immunity.
PubMed Identifier: 40730233
author list: Choi JH, Kagan JC
published in: Open biology
information resource reference: Oxidized phospholipid damage signals as modulators of immunity. Open Biol. 2025 Jul; 15(7):240391.
journal title abbreviation: Open Biol
publication date: 2025-07-30T00:00:00
year: 2025
type: Academic Article
type: Article
type: Document
type: Information Resource

MAVS oligomerization drives a faster and more efficient antiviral signaling activation at peroxisomes compared to mitochondria.
PubMed Identifier: 41348376
author list: Ramos B, Sarabando J, Marques M, Kagan JC, Ribeiro D
published in: The FEBS journal
information resource reference: MAVS oligomerization drives a faster and more efficient antiviral signaling activation at peroxisomes compared to mitochondria. FEBS J. 2026 Apr; 293(7):2086-2097.
journal title abbreviation: FEBS J
publication date: 2025-12-05T00:00:00
year: 2025
type: Academic Article
type: Article
type: Document
type: Information Resource

NLRP11 promotes non-canonical inflammasome activation in human macrophages by enhancing caspase-4 recognition of cytosolic lipopolysaccharide.
PubMed Identifier: 41676729
author list: Gil-Marqués ML, Devant P, Kagan JC, Goldberg MB
published in: bioRxiv : the preprint server for biology
information resource reference: NLRP11 promotes non-canonical inflammasome activation in human macrophages by enhancing caspase-4 recognition of cytosolic lipopolysaccharide. bioRxiv. 2026 Feb 04.
journal title abbreviation: bioRxiv
publication date: 2026-02-04T00:00:00
year: 2026
type: Academic Article
type: Article
type: Document
type: Information Resource

Strategy management in collaborative clinical research partnerships.
PubMed Identifier: 34729443
author list: Kagan J, Lassa J, Zuckerman J, Cull E, Boan D, Lysander J, Njoh W, Johnson K, Sardana R, Stern K, Grace B, McNay L, Tegli J
published in: Contemporary clinical trials communications
information resource reference: Strategy management in collaborative clinical research partnerships. Contemp Clin Trials Commun. 2021 Dec; 24:100833.
journal title abbreviation: Contemp Clin Trials Commun
publication date: 2021-08-18T00:00:00
year: 2021
type: Academic Article
type: Article
type: Document
type: Information Resource

Towards a molecular and structural definition of cell death.
PubMed Identifier: 40968156
author list: Arama E, Cosentino K, Czabotar PE, Gan B, Hartland E, Jiang X, Kagan JC, Nagata S, Schroder K, Sun L, Xu D, Yuan J
published in: Nature structural & molecular biology
information resource reference: Towards a molecular and structural definition of cell death. Nat Struct Mol Biol. 2025 Oct; 32(10):1854-1858.
journal title abbreviation: Nat Struct Mol Biol
publication date: 2025-10-01T00:00:00
year: 2025
type: Academic Article
type: Article
type: Document
type: Information Resource

Gastroenterology & Nutrition
type: Division
type: Organization

Research Fellow in Pediatrics
is primary position: true
position in department: Pediatrics
position in division: Gastroenterology & Nutrition
sort order: 1
type: Position
HR job title: Research Fellow in Pediatrics
position in organization: Boston Children's Hospital

Professor of Pediatrics
is primary position: true
position in department: Pediatrics
position in division: Gastroenterology & Nutrition
sort order: 1
type: Position
HR job title: Professor of Pediatrics
position in organization: Boston Children's Hospital

Professor of Pediatrics
is primary position: true
position in department: Pediatrics
position in division: Gastroenterology & Nutrition
sort order: 1
type: Position
HR job title: Professor of Pediatrics
position in organization: Boston Children's Hospital

Professor of Pediatrics
is primary position: true
position in department: Pediatrics
position in division: Precision Vaccines
sort order: 1
type: Position
HR job title: Professor of Pediatrics
position in organization: Boston Children's Hospital

Marian R. Neutra, PhD Professor of Pediatrics
is primary position: true
position in department: Pediatrics
position in division: Gastroenterology & Nutrition
sort order: 1
type: Position
HR job title: Marian R. Neutra, PhD Professor of Pediatrics
position in organization: Boston Children's Hospital

Assistant Professor of Pediatrics
is primary position: true
position in department: Pediatrics
position in division: Gastroenterology & Nutrition
sort order: 1
type: Position
HR job title: Assistant Professor of Pediatrics
position in organization: Boston Children's Hospital

Assistant Professor of Pediatrics
is primary position: true
position in department: Pediatrics
position in division: Gastroenterology & Nutrition
sort order: 1
type: Position
HR job title: Assistant Professor of Pediatrics
position in organization: Boston Children's Hospital

Assistant Professor of Pediatrics
is primary position: true
position in department: Pediatrics
position in division: Gastroenterology & Nutrition
sort order: 1
type: Position
HR job title: Assistant Professor of Pediatrics
position in organization: Boston Children's Hospital

Professor of Pediatrics
is primary position: true
position in department: Pediatrics
position in division: Gastroenterology & Nutrition
sort order: 1
type: Position
HR job title: Professor of Pediatrics
position in organization: Boston Children's Hospital

Authorship 383567
type: Authorship
author rank in publication: 6
linked author: Kagan, Jonathan
linked information resource: Influences of gender and social class on adolescents' perceptions of health.

Authorship 473247
type: Authorship
author rank in publication: 2
linked author: Kagan, Jonathan
linked information resource: Daylength during pregnancy and shyness in children: results from northern and southern hemispheres.

Authorship 747537
type: Authorship
author rank in publication: 10
linked author: Kagan, Jonathan
linked information resource: Diverse intracellular pathogens activate type III interferon expression from peroxisomes.

Authorship 749630
type: Authorship
author rank in publication: 2
linked author: Kagan, Jonathan
linked information resource: Late endosomal trafficking of alternative serotype adenovirus vaccine vectors augments antiviral innate immunity.

Late endosomal trafficking of alternative serotype adenovirus vaccine vectors augments antiviral innate immunity.
PubMed Identifier: 24991003
author list: Teigler JE, Kagan JC, Barouch DH
published in: Journal of virology
information resource reference: Late endosomal trafficking of alternative serotype adenovirus vaccine vectors augments antiviral innate immunity. J Virol. 2014 Sep; 88(18):10354-63.
journal title abbreviation: J Virol
publication date: 2014-07-02T00:00:00
year: 2014
type: Academic Article
type: Article
type: Document
type: Information Resource

Diverse intracellular pathogens activate type III interferon expression from peroxisomes.
PubMed Identifier: 24952503
author list: Odendall C, Dixit E, Stavru F, Bierne H, Franz KM, Durbin AF, Boulant S, Gehrke L, Cossart P, Kagan JC
published in: Nature immunology
information resource reference: Diverse intracellular pathogens activate type III interferon expression from peroxisomes. Nat Immunol. 2014 Aug; 15(8):717-26.
journal title abbreviation: Nat Immunol
publication date: 2014-06-22T00:00:00
year: 2014
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 762416
type: Authorship
author rank in publication: 1
linked author: Kagan, Jonathan
linked information resource: Common mechanisms activate plant guard receptors and TLR4.

Common mechanisms activate plant guard receptors and TLR4.
PubMed Identifier: 25224694
author list: Kagan JC
published in: Trends in immunology
information resource reference: Common mechanisms activate plant guard receptors and TLR4. Trends Immunol. 2014 Oct; 35(10):454-6.
journal title abbreviation: Trends Immunol
publication date: 2014-09-12T00:00:00
year: 2014
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 439503
type: Authorship
author rank in publication: 1
linked author: Kagan, Jonathan
linked information resource: Recycling endosomes and TLR signaling--the Rab11 GTPase leads the way.

SMOCs: supramolecular organizing centres that control innate immunity.
PubMed Identifier: 25359439
author list: Kagan JC, Magupalli VG, Wu H
published in: Nature reviews. Immunology
information resource reference: SMOCs: supramolecular organizing centres that control innate immunity. Nat Rev Immunol. 2014 12; 14(12):821-6.
journal title abbreviation: Nat Rev Immunol
publication date: 2014-10-31T00:00:00
year: 2014
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 769102
type: Authorship
author rank in publication: 10
linked author: Kagan, Jonathan
linked information resource: ACT2 peer-driven intervention increases enrollment into HIV/AIDS medical studies among African Americans/Blacks and Hispanics: A cluster randomized controlled trial.

ACT2 peer-driven intervention increases enrollment into HIV/AIDS medical studies among African Americans/Blacks and Hispanics: A cluster randomized controlled trial.
PubMed Identifier: 24961193
author list: Gwadz M, Cleland CM, Belkin M, Ritchie A, Leonard N, Riedel M, Banfield A, Colon P, Elharrar V, Kagan J, Mildvan D
published in: AIDS and behavior
information resource reference: ACT2 peer-driven intervention increases enrollment into HIV/AIDS medical studies among African Americans/Blacks and Hispanics: A cluster randomized controlled trial. AIDS Behav. 2014 Dec; 18(12):2409-22.
journal title abbreviation: AIDS Behav
publication date: 2014-12-01T00:00:00
year: 2014
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 771226
type: Authorship
author rank in publication: 1
linked author: Kagan, Jonathan
linked information resource: SMOCs: supramolecular organizing centres that control innate immunity.

Authorship 426436
type: Authorship
author rank in publication: 2
linked author: Kagan, Jonathan
linked information resource: Identification of Icm protein complexes that play distinct roles in the biogenesis of an organelle permissive for Legionella pneumophila intracellular growth.

Authorship 30080
type: Authorship
author rank in publication: 8
linked author: Kagan, Jonathan
linked information resource: Cloning and expression of the human substance K receptor and analysis of its role in mitogenesis.

Authorship 454559
type: Authorship
author rank in publication: 6
linked author: Kagan, Jonathan
linked information resource: Genetic association analysis of behavioral inhibition using candidate loci from mouse models.

Authorship 357853
type: Authorship
author rank in publication: 8
linked author: Kagan, Jonathan
linked information resource: Psychiatric correlates of behavioral inhibition in young children of parents with and without psychiatric disorders.

Authorship 509647
type: Authorship
author rank in publication: 5
linked author: Kagan, Jonathan
linked information resource: Three-color supplement to the NIAID DAIDS guideline for flow cytometric immunophenotyping.

Authorship 180041
type: Authorship
author rank in publication: 8
linked author: Kagan, Jonathan
linked information resource: Association of selected phenotypic markers of lymphocyte activation and differentiation with perinatal human immunodeficiency virus transmission and infant infection.

Authorship 84782
type: Authorship
author rank in publication: 3
linked author: Kagan, Jonathan
linked information resource: A C-terminal translocation signal required for Dot/Icm-dependent delivery of the Legionella RalF protein to host cells.

Authorship 477068
type: Authorship
author rank in publication: 7
linked author: Kagan, Jonathan
linked information resource: Behavioral inhibition in children of parents with panic disorder and agoraphobia. A controlled study.

Authorship 357041
type: Authorship
author rank in publication: 2
linked author: Kagan, Jonathan
linked information resource: Intracellular localization of Toll-like receptor 9 prevents recognition of self DNA but facilitates access to viral DNA.

Authorship 229475
type: Authorship
author rank in publication: 4
linked author: Kagan, Jonathan
linked information resource: A phenotype of early infancy predicts reactivity of the amygdala in male adults.

Authorship 298356
type: Authorship
author rank in publication: 11
linked author: Kagan, Jonathan
linked information resource: https://connects.catalyst.harvard.edu/Profiles/profile/974303

Authorship 236176
type: Authorship
author rank in publication: 4
linked author: Kagan, Jonathan
linked information resource: Interferon ß is associated with type 1 interferon-inducible gene expression in dermatomyositis.

Authorship 297007
type: Authorship
author rank in publication: 7
linked author: Kagan, Jonathan
linked information resource: Safety of autologous, ex vivo-expanded human immunodeficiency virus (HIV)-specific cytotoxic T-lymphocyte infusion in HIV-infected patients.

Authorship 373338
type: Authorship
author rank in publication: 9
linked author: Kagan, Jonathan
linked information resource: Efficacy of a mixed amphetamine salts compound in adults with attention-deficit/hyperactivity disorder.

Authorship 459251
type: Authorship
author rank in publication: 6
linked author: Kagan, Jonathan
linked information resource: Polymorphisms in toll-like receptor 4 underlie susceptibility to tumor induction by the mouse polyomavirus.

Authorship 802732
type: Authorship
author rank in publication: 1
linked author: Kagan, Jonathan
linked information resource: Emerging principles governing signal transduction by pattern-recognition receptors.

Authorship 799614
type: Authorship
author rank in publication: 4
linked author: Kagan, Jonathan
linked information resource: Innate immune pattern recognition: a cell biological perspective.

Authorship 790804
type: Authorship
author rank in publication: 2
linked author: Kagan, Jonathan
linked information resource: Microbial strategies for antagonizing Toll-like-receptor signal transduction.

Emerging principles governing signal transduction by pattern-recognition receptors.
PubMed Identifier: 25395297
author list: Kagan JC, Barton GM
published in: Cold Spring Harbor perspectives in biology
information resource reference: Emerging principles governing signal transduction by pattern-recognition receptors. Cold Spring Harb Perspect Biol. 2014 Nov 13; 7(3):a016253.
journal title abbreviation: Cold Spring Harb Perspect Biol
publication date: 2014-11-13T00:00:00
year: 2014
type: Academic Article
type: Article
type: Document
type: Information Resource

Microbial strategies for antagonizing Toll-like-receptor signal transduction.
PubMed Identifier: 25615700
author list: Rosadini CV, Kagan JC
published in: Current opinion in immunology
information resource reference: Microbial strategies for antagonizing Toll-like-receptor signal transduction. Curr Opin Immunol. 2015 Feb; 32:61-70.
journal title abbreviation: Curr Opin Immunol
publication date: 2015-01-20T00:00:00
year: 2015
type: Academic Article
type: Article
type: Document
type: Information Resource

Innate immune pattern recognition: a cell biological perspective.
PubMed Identifier: 25581309
author list: Brubaker SW, Bonham KS, Zanoni I, Kagan JC
published in: Annual review of immunology
information resource reference: Innate immune pattern recognition: a cell biological perspective. Annu Rev Immunol. 2015; 33:257-90.
journal title abbreviation: Annu Rev Immunol
publication date: 2015-01-02T00:00:00
year: 2015
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 30668
type: Authorship
author rank in publication: 8
linked author: Kagan, Jonathan
linked information resource: Interlaboratory variability of CD8 subset measurements by flow cytometry and its applications to multicenter clinical trials. NAID/NICHD Women and Infants Transmission Study Group.

Authorship 362747
type: Authorship
author rank in publication: 4
linked author: Kagan, Jonathan
linked information resource: A controlled study of behavioral inhibition in children of parents with panic disorder and depression.

Authorship 393044
type: Authorship
author rank in publication: 7
linked author: Kagan, Jonathan
linked information resource: Serum neopterin, an immune activation marker, independently predicts disease progression in advanced HIV-1 infection.

Authorship 482046
type: Authorship
author rank in publication: 13
linked author: Kagan, Jonathan
linked information resource: Peroxisomes are signaling platforms for antiviral innate immunity.

Authorship 811398
type: Authorship
author rank in publication: 3
linked author: Kagan, Jonathan
linked information resource: PRRs are watching you: Localization of innate sensing and signaling regulators.

PRRs are watching you: Localization of innate sensing and signaling regulators.
PubMed Identifier: 25800355
author list: Chow J, Franz KM, Kagan JC
published in: Virology
information resource reference: PRRs are watching you: Localization of innate sensing and signaling regulators. Virology. 2015 May; 479-480:104-9.
journal title abbreviation: Virology
publication date: 2015-03-20T00:00:00
year: 2015
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 824458
type: Authorship
author rank in publication: 2
linked author: Kagan, Jonathan
linked information resource: The unique regulation and functions of type III interferons in antiviral immunity.

The unique regulation and functions of type III interferons in antiviral immunity.
PubMed Identifier: 25771505
author list: Odendall C, Kagan JC
published in: Current opinion in virology
information resource reference: The unique regulation and functions of type III interferons in antiviral immunity. Curr Opin Virol. 2015 Jun; 12:47-52.
journal title abbreviation: Curr Opin Virol
publication date: 2015-03-12T00:00:00
year: 2015
type: Academic Article
type: Article
type: Document
type: Information Resource

Mechanisms of Toll-like Receptor 4 Endocytosis Reveal a Common Immune-Evasion Strategy Used by Pathogenic and Commensal Bacteria.
PubMed Identifier: 26546281
author list: Tan Y, Zanoni I, Cullen TW, Goodman AL, Kagan JC
published in: Immunity
information resource reference: Mechanisms of Toll-like Receptor 4 Endocytosis Reveal a Common Immune-Evasion Strategy Used by Pathogenic and Commensal Bacteria. Immunity. 2015 Nov 17; 43(5):909-22.
journal title abbreviation: Immunity
publication date: 2015-11-03T00:00:00
year: 2015
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 847096
type: Authorship
author rank in publication: 5
linked author: Kagan, Jonathan
linked information resource: Mechanisms of Toll-like Receptor 4 Endocytosis Reveal a Common Immune-Evasion Strategy Used by Pathogenic and Commensal Bacteria.

Authorship 853260
type: Authorship
author rank in publication: 9
linked author: Kagan, Jonathan
linked information resource: A Single Bacterial Immune Evasion Strategy Dismantles Both MyD88 and TRIF Signaling Pathways Downstream of TLR4.

A Single Bacterial Immune Evasion Strategy Dismantles Both MyD88 and TRIF Signaling Pathways Downstream of TLR4.
PubMed Identifier: 26651944
author list: Rosadini CV, Zanoni I, Odendall C, Green ER, Paczosa MK, Philip NH, Brodsky IE, Mecsas J, Kagan JC
published in: Cell host & microbe
information resource reference: A Single Bacterial Immune Evasion Strategy Dismantles Both MyD88 and TRIF Signaling Pathways Downstream of TLR4. Cell Host Microbe. 2015 Dec 09; 18(6):682-93.
journal title abbreviation: Cell Host Microbe
publication date: 2015-12-09T00:00:00
year: 2015
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 872971
type: Authorship
author rank in publication: 6
linked author: Kagan, Jonathan
linked information resource: Hepatitis C virus NS3-4A inhibits the peroxisomal MAVS-dependent antiviral signalling response.

Hepatitis C virus NS3-4A inhibits the peroxisomal MAVS-dependent antiviral signalling response.
PubMed Identifier: 26865163
author list: Ferreira AR, Magalhães AC, Camões F, Gouveia A, Vieira M, Kagan JC, Ribeiro D
published in: Journal of cellular and molecular medicine
information resource reference: Hepatitis C virus NS3-4A inhibits the peroxisomal MAVS-dependent antiviral signalling response. J Cell Mol Med. 2016 Apr; 20(4):750-7.
journal title abbreviation: J Cell Mol Med
publication date: 2016-02-10T00:00:00
year: 2016
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 881212
type: Authorship
author rank in publication: 10
linked author: Kagan, Jonathan
linked information resource: Peroxisomes are platforms for cytomegalovirus' evasion from the cellular immune response.

Peroxisomes are platforms for cytomegalovirus' evasion from the cellular immune response.
PubMed Identifier: 27181750
author list: Magalhães AC, Ferreira AR, Gomes S, Vieira M, Gouveia A, Valença I, Islinger M, Nascimento R, Schrader M, Kagan JC, Ribeiro D
published in: Scientific reports
information resource reference: Peroxisomes are platforms for cytomegalovirus' evasion from the cellular immune response. Sci Rep. 2016 05 16; 6:26028.
journal title abbreviation: Sci Rep
publication date: 2016-05-16T00:00:00
year: 2016
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 884789
type: Authorship
author rank in publication: 11
linked author: Kagan, Jonathan
linked information resource: An endogenous caspase-11 ligand elicits interleukin-1 release from living dendritic cells.

An endogenous caspase-11 ligand elicits interleukin-1 release from living dendritic cells.
PubMed Identifier: 27103670
author list: Zanoni I, Tan Y, Di Gioia M, Broggi A, Ruan J, Shi J, Donado CA, Shao F, Wu H, Springstead JR, Kagan JC
published in: Science (New York, N.Y.)
information resource reference: An endogenous caspase-11 ligand elicits interleukin-1 release from living dendritic cells. Science. 2016 Jun 03; 352(6290):1232-6.
journal title abbreviation: Science
publication date: 2016-04-21T00:00:00
year: 2016
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 96787
type: Authorship
author rank in publication: 7
linked author: Kagan, Jonathan
linked information resource: Impact of tic disorders on ADHD outcome across the life cycle: findings from a large group of adults with and without ADHD.

Assistant Professor
sort order: 2
type: Faculty Rank

Fellow or Post Doc
sort order: 6
type: Faculty Rank

Full Professor
sort order: 0
type: Faculty Rank

Instructor
sort order: 4
type: Faculty Rank

Other Faculty
sort order: 5
type: Faculty Rank

Okin, Daniel
eCommons Login: DAO10
first name: Daniel
last name: Okin
full name: Daniel Andrew Okin, M.D., Ph.D.
has faculty rank: Instructor
Person ID: 150668
person in primary position: Instructor in Medicine
type: Agent
type: Person
preferred title: Instructor in Medicine

Authorship 893343
type: Authorship
author rank in publication: 18
linked author: Kagan, Jonathan
linked information resource: Control of the innate immune response by the mevalonate pathway.

Control of the innate immune response by the mevalonate pathway.
PubMed Identifier: 27270400
author list: Akula MK, Shi M, Jiang Z, Foster CE, Miao D, Li AS, Zhang X, Gavin RM, Forde SD, Germain G, Carpenter S, Rosadini CV, Gritsman K, Chae JJ, Hampton R, Silverman N, Gravallese EM, Kagan JC, Fitzgerald KA, Kastner DL, Golenbock DT, Bergo MO, Wang D
published in: Nature immunology
information resource reference: Control of the innate immune response by the mevalonate pathway. Nat Immunol. 2016 08; 17(8):922-9.
journal title abbreviation: Nat Immunol
publication date: 2016-06-06T00:00:00
year: 2016
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 584395
type: Authorship
linked author: Kagan, Jonathan
linked information resource: Cellular and Molecular Aspects of Legionella pneumophila transport to the endoplasmic reticulum

Authorship 76064
type: Authorship
author rank in publication: 1
linked author: Kagan, Jonathan
linked information resource: Legionella phagosomes intercept vesicular traffic from endoplasmic reticulum exit sites.

Authorship 901283
type: Authorship
author rank in publication: 1
linked author: Kagan, Jonathan
linked information resource: Editorial overview: Emerging concepts in host-virus interactions.

Editorial overview: Emerging concepts in host-virus interactions.
PubMed Identifier: 27426076
author list: Kagan JC
published in: Current opinion in microbiology
information resource reference: Editorial overview: Emerging concepts in host-virus interactions. Curr Opin Microbiol. 2016 08; 32:xii-xiii.
journal title abbreviation: Curr Opin Microbiol
publication date: 2016-07-11T00:00:00
year: 2016
type: Academic Article
type: Article
type: Document
type: Information Resource

Initiation and regulation of antibacterial innate immunity
end date: 2015-07-31
principal investigator name: KAGAN, JONATHAN C
start date: 2014-08-01
type: Grant
sponsor award id: R56AI113141

Defining non-transcriptional innate immune responses to bacterial endotoxin
end date: 2015-04-30
principal investigator name: KAGAN, JONATHAN C
start date: 2013-05-16
type: Grant
sponsor award id: R56AI103082

Cellular and molecular aspects of Toll-like receptor signal transduction.
end date: 2011-01-31
principal investigator name: KAGAN, JONATHAN C
start date: 2006-12-01
type: Grant
sponsor award id: R00AI072955

Initiation and Regulation of Antiviral Innate Immunity
end date: 2021-02-28
principal investigator name: KAGAN, JONATHAN C
start date: 2011-03-01
type: Grant
sponsor award id: R01AI093589

Cellular and molecular aspects of Toll-like receptor signal transduction.
end date: 2007-11-30
principal investigator name: KAGAN, JONATHAN C
start date: 2006-12-01
type: Grant
sponsor award id: K99AI072955

Principal Investigator
type: Researcher Role
researcher role of: Kagan, Jonathan
contributes to: Cellular and molecular aspects of Toll-like receptor signal transduction.

Principal Investigator
type: Researcher Role
researcher role of: Kagan, Jonathan
contributes to: Defining non-transcriptional innate immune responses to bacterial endotoxin

Principal Investigator
type: Researcher Role
researcher role of: Kagan, Jonathan
contributes to: Cellular and molecular aspects of Toll-like receptor signal transduction.

Principal Investigator
type: Researcher Role
researcher role of: Kagan, Jonathan
contributes to: Initiation and regulation of antibacterial innate immunity

Principal Investigator
type: Researcher Role
researcher role of: Kagan, Jonathan
contributes to: Initiation and Regulation of Antiviral Innate Immunity

Authorship 80644
type: Authorship
author rank in publication: 2
linked author: Kagan, Jonathan
linked information resource: Deciphering the function of nucleic acid sensing TLRs one regulatory step at a time.

Authorship 363973
type: Authorship
author rank in publication: 8
linked author: Kagan, Jonathan
linked information resource: Stable behavioral inhibition and its association with anxiety disorder.

Authorship 928790
type: Authorship
author rank in publication: 2
linked author: Kagan, Jonathan
linked information resource: Microbe-inducible trafficking pathways that control Toll-like receptor signaling.

Microbe-inducible trafficking pathways that control Toll-like receptor signaling.
PubMed Identifier: 27731905
author list: Tan Y, Kagan JC
published in: Traffic (Copenhagen, Denmark)
information resource reference: Microbe-inducible trafficking pathways that control Toll-like receptor signaling. Traffic. 2017 01; 18(1):6-17.
journal title abbreviation: Traffic
publication date: 2016-11-23T00:00:00
year: 2016
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 420473
type: Authorship
author rank in publication: 1
linked author: Kagan, Jonathan
linked information resource: TRAM couples endocytosis of Toll-like receptor 4 to the induction of interferon-beta.

Authorship 575482
type: Authorship
author rank in publication: 5
linked author: Kagan, Jonathan
linked information resource: An approach to the validation of markers for use in AIDS clinical trials.

Authorship 931209
type: Authorship
author rank in publication: 10
linked author: Kagan, Jonathan
linked information resource: Biomarkers of Environmental Enteropathy, Inflammation, Stunting, and Impaired Growth in Children in Northeast Brazil.

Authorship 932865
type: Authorship
author rank in publication: 1
linked author: Kagan, Jonathan
linked information resource: Assessing Clinical Research Capacity in Vietnam: A Framework for Strengthening Capability for Clinical Trials in Developing Countries.

Authorship 934257
type: Authorship
author rank in publication: 2
linked author: Kagan, Jonathan
linked information resource: Early innate immune responses to bacterial LPS.

Biomarkers of Environmental Enteropathy, Inflammation, Stunting, and Impaired Growth in Children in Northeast Brazil.
PubMed Identifier: 27690129
author list: Guerrant RL, Leite AM, Pinkerton R, Medeiros PH, Cavalcante PA, DeBoer M, Kosek M, Duggan C, Gewirtz A, Kagan JC, Gauthier AE, Swann J, Mayneris-Perxachs J, Bolick DT, Maier EA, Guedes MM, Moore SR, Petri WA, Havt A, Lima IF, Prata MM, Michaleckyj JC, Scharf RJ, Sturgeon C, Fasano A, Lima AA
published in: PloS one
information resource reference: Biomarkers of Environmental Enteropathy, Inflammation, Stunting, and Impaired Growth in Children in Northeast Brazil. PLoS One. 2016; 11(9):e0158772.
journal title abbreviation: PLoS One
publication date: 2016-09-30T00:00:00
year: 2016
type: Academic Article
type: Article
type: Document
type: Information Resource

Early innate immune responses to bacterial LPS.
PubMed Identifier: 27842237
author list: Rosadini CV, Kagan JC
published in: Current opinion in immunology
information resource reference: Early innate immune responses to bacterial LPS. Curr Opin Immunol. 2017 Feb; 44:14-19.
journal title abbreviation: Curr Opin Immunol
publication date: 2016-11-12T00:00:00
year: 2016
type: Academic Article
type: Article
type: Document
type: Information Resource

Assessing Clinical Research Capacity in Vietnam: A Framework for Strengthening Capability for Clinical Trials in Developing Countries.
PubMed Identifier: 27252559
author list: Kagan J, Giang DD, Iademarco MF, Phung VT, Lau CY, Quang NN
published in: Public health reports (Washington, D.C. : 1974)
information resource reference: Assessing Clinical Research Capacity in Vietnam: A Framework for Strengthening Capability for Clinical Trials in Developing Countries. Public Health Rep. 2016 May-Jun; 131(3):396-403.
journal title abbreviation: Public Health Rep
publication date: 2016-05-01T00:00:00
year: 2016
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 195505
type: Authorship
author rank in publication: 7
linked author: Kagan, Jonathan
linked information resource: Behavioral inhibition in childhood: a risk factor for anxiety disorders.

Authorship 238745
type: Authorship
author rank in publication: 7
linked author: Kagan, Jonathan
linked information resource: Immunophenotypic markers and antiretroviral therapy (IMART): T cell activation and maturation help predict treatment response.

Characterization of the myddosome, a protein complex that controls TLR signaling
end date: 2026-01-31
principal investigator name: KAGAN, JONATHAN C
start date: 2016-12-13
type: Grant
sponsor award id: R01AI116550

Principal Investigator
type: Researcher Role
researcher role of: Kagan, Jonathan
contributes to: Characterization of the myddosome, a protein complex that controls TLR signaling

Authorship 951257
type: Authorship
author rank in publication: 2
linked author: Kagan, Jonathan
linked information resource: Activation and pathogenic manipulation of the sensors of the innate immune system.

Activation and pathogenic manipulation of the sensors of the innate immune system.
PubMed Identifier: 28093320
author list: Odendall C, Kagan JC
published in: Microbes and infection
information resource reference: Activation and pathogenic manipulation of the sensors of the innate immune system. Microbes Infect. 2017 Apr - May; 19(4-5):229-237.
journal title abbreviation: Microbes Infect
publication date: 2017-01-14T00:00:00
year: 2017
type: Academic Article
type: Article
type: Document
type: Information Resource

Intracellular localization of Toll-like receptor 9 prevents recognition of self DNA but facilitates access to viral DNA.
PubMed Identifier: 16341217
author list: Barton GM, Kagan JC, Medzhitov R
published in: Nature immunology
information resource reference: Intracellular localization of Toll-like receptor 9 prevents recognition of self DNA but facilitates access to viral DNA. Nat Immunol. 2006 Jan; 7(1):49-56.
journal title abbreviation: Nat Immunol
publication date: 2005-12-11T00:00:00
year: 2005
type: Academic Article
type: Article
type: Document
type: Information Resource

Comorbidity of parental anxiety disorders as risk for childhood-onset anxiety in inhibited children.
PubMed Identifier: 1554032
author list: Rosenbaum JF, Biederman J, Bolduc EA, Hirshfeld DR, Faraone SV, Kagan J
published in: The American journal of psychiatry
information resource reference: Comorbidity of parental anxiety disorders as risk for childhood-onset anxiety in inhibited children. Am J Psychiatry. 1992 Apr; 149(4):475-81.
journal title abbreviation: Am J Psychiatry
publication date: 1992-04-01T00:00:00
year: 1992
type: Academic Article
type: Article
type: Document
type: Information Resource

Cloning and expression of the human substance K receptor and analysis of its role in mitogenesis.
PubMed Identifier: 1848773
author list: Kris RM, South V, Saltzman A, Felder S, Ricca GA, Jaye M, Huebner K, Kagan J, Croce CM, Schlessinger J
published in: Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research
information resource reference: Cloning and expression of the human substance K receptor and analysis of its role in mitogenesis. Cell Growth Differ. 1991 Jan; 2(1):15-22.
journal title abbreviation: Cell Growth Differ
publication date: 1991-01-01T00:00:00
year: 1991
type: Academic Article
type: Article
type: Document
type: Information Resource

Adolescent social anxiety as an outcome of inhibited temperament in childhood.
PubMed Identifier: 10434493
author list: Schwartz CE, Snidman N, Kagan J
published in: Journal of the American Academy of Child and Adolescent Psychiatry
information resource reference: Adolescent social anxiety as an outcome of inhibited temperament in childhood. J Am Acad Child Adolesc Psychiatry. 1999 Aug; 38(8):1008-15.
journal title abbreviation: J Am Acad Child Adolesc Psychiatry
publication date: 1999-08-01T00:00:00
year: 1999
type: Academic Article
type: Article
type: Document
type: Information Resource

Stable behavioral inhibition and its association with anxiety disorder.
PubMed Identifier: 1537760
author list: Hirshfeld DR, Rosenbaum JF, Biederman J, Bolduc EA, Faraone SV, Snidman N, Reznick JS, Kagan J
published in: Journal of the American Academy of Child and Adolescent Psychiatry
information resource reference: Stable behavioral inhibition and its association with anxiety disorder. J Am Acad Child Adolesc Psychiatry. 1992 Jan; 31(1):103-11.
journal title abbreviation: J Am Acad Child Adolesc Psychiatry
publication date: 1992-01-01T00:00:00
year: 1992
type: Academic Article
type: Article
type: Document
type: Information Resource

A controlled study of behavioral inhibition in children of parents with panic disorder and depression.
PubMed Identifier: 11097967
author list: Rosenbaum JF, Biederman J, Hirshfeld-Becker DR, Kagan J, Snidman N, Friedman D, Nineberg A, Gallery DJ, Faraone SV
published in: The American journal of psychiatry
information resource reference: A controlled study of behavioral inhibition in children of parents with panic disorder and depression. Am J Psychiatry. 2000 Dec; 157(12):2002-10.
journal title abbreviation: Am J Psychiatry
publication date: 2000-12-01T00:00:00
year: 2000
type: Academic Article
type: Article
type: Document
type: Information Resource

Can immune markers predict subsequent discordance between immunologic and virologic responses to antiretroviral therapy? Adult AIDS Clinical Trials Group.
PubMed Identifier: 12905140
author list: Spritzler J, Mildvan D, Russo A, Asthana D, Livnat D, Schock B, Kagan J, Landay A, Haas DW
published in: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
information resource reference: Can immune markers predict subsequent discordance between immunologic and virologic responses to antiretroviral therapy? Adult AIDS Clinical Trials Group. Clin Infect Dis. 2003 Aug 15; 37(4):551-8.
journal title abbreviation: Clin Infect Dis
publication date: 2003-07-29T00:00:00
year: 2003
type: Academic Article
type: Article
type: Document
type: Information Resource

Further evidence of association between behavioral inhibition and social anxiety in children.
PubMed Identifier: 11579001
author list: Biederman J, Hirshfeld-Becker DR, Rosenbaum JF, Hérot C, Friedman D, Snidman N, Kagan J, Faraone SV
published in: The American journal of psychiatry
information resource reference: Further evidence of association between behavioral inhibition and social anxiety in children. Am J Psychiatry. 2001 Oct; 158(10):1673-9.
journal title abbreviation: Am J Psychiatry
publication date: 2001-10-01T00:00:00
year: 2001
type: Academic Article
type: Article
type: Document
type: Information Resource

Identification of Icm protein complexes that play distinct roles in the biogenesis of an organelle permissive for Legionella pneumophila intracellular growth.
PubMed Identifier: 11115108
author list: Coers J, Kagan JC, Matthews M, Nagai H, Zuckman DM, Roy CR
published in: Molecular microbiology
information resource reference: Identification of Icm protein complexes that play distinct roles in the biogenesis of an organelle permissive for Legionella pneumophila intracellular growth. Mol Microbiol. 2000 Nov; 38(4):719-36.
journal title abbreviation: Mol Microbiol
publication date: 2000-11-01T00:00:00
year: 2000
type: Academic Article
type: Article
type: Document
type: Information Resource

Peroxisomes are signaling platforms for antiviral innate immunity.
PubMed Identifier: 20451243
author list: Dixit E, Boulant S, Zhang Y, Lee AS, Odendall C, Shum B, Hacohen N, Chen ZJ, Whelan SP, Fransen M, Nibert ML, Superti-Furga G, Kagan JC
published in: Cell
information resource reference: Peroxisomes are signaling platforms for antiviral innate immunity. Cell. 2010 May 14; 141(4):668-81.
journal title abbreviation: Cell
publication date: 2010-05-06T00:00:00
year: 2010
type: Academic Article
type: Article
type: Document
type: Information Resource

Microtubule motors control membrane dynamics of Salmonella-containing vacuoles.
PubMed Identifier: 14970261
author list: Guignot J, Caron E, Beuzón C, Bucci C, Kagan J, Roy C, Holden DW
published in: Journal of cell science
information resource reference: Microtubule motors control membrane dynamics of Salmonella-containing vacuoles. J Cell Sci. 2004 Mar 01; 117(Pt 7):1033-45.
journal title abbreviation: J Cell Sci
publication date: 2004-02-17T00:00:00
year: 2004
type: Academic Article
type: Article
type: Document
type: Information Resource

Behavioral inhibition in children of parents with panic disorder and agoraphobia. A controlled study.
PubMed Identifier: 3358645
author list: Rosenbaum JF, Biederman J, Gersten M, Hirshfeld DR, Meminger SR, Herman JB, Kagan J, Reznick JS, Snidman N
published in: Archives of general psychiatry
information resource reference: Behavioral inhibition in children of parents with panic disorder and agoraphobia. A controlled study. Arch Gen Psychiatry. 1988 May; 45(5):463-70.
journal title abbreviation: Arch Gen Psychiatry
publication date: 1988-05-01T00:00:00
year: 1988
type: Academic Article
type: Article
type: Document
type: Information Resource

Association of selected phenotypic markers of lymphocyte activation and differentiation with perinatal human immunodeficiency virus transmission and infant infection.
PubMed Identifier: 15879023
author list: Lambert JS, Moye J, Plaeger SF, Stiehm ER, Bethel J, Mofenson LM, Mathieson B, Kagan J, Rosenblatt H, Paxton H, Suter H, Landay A
published in: Clinical and diagnostic laboratory immunology
information resource reference: Association of selected phenotypic markers of lymphocyte activation and differentiation with perinatal human immunodeficiency virus transmission and infant infection. Clin Diagn Lab Immunol. 2005 May; 12(5):622-31.
journal title abbreviation: Clin Diagn Lab Immunol
publication date: 2005-05-01T00:00:00
year: 2005
type: Academic Article
type: Article
type: Document
type: Information Resource

A phenotype of early infancy predicts reactivity of the amygdala in male adults.
PubMed Identifier: 21894151
author list: Schwartz CE, Kunwar PS, Greve DN, Kagan J, Snidman NC, Bloch RB
published in: Molecular psychiatry
information resource reference: A phenotype of early infancy predicts reactivity of the amygdala in male adults. Mol Psychiatry. 2012 Oct; 17(10):1042-50.
journal title abbreviation: Mol Psychiatry
publication date: 2011-09-06T00:00:00
year: 2011
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 985728
type: Authorship
author rank in publication: 1
linked author: Kagan, Jonathan
linked information resource: Lipopolysaccharide Detection across the Kingdoms of Life.

Lipopolysaccharide Detection across the Kingdoms of Life.
PubMed Identifier: 28551077
author list: Kagan JC
published in: Trends in immunology
information resource reference: Lipopolysaccharide Detection across the Kingdoms of Life. Trends Immunol. 2017 10; 38(10):696-704.
journal title abbreviation: Trends Immunol
publication date: 2017-05-24T00:00:00
year: 2017
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 988992
type: Authorship
author rank in publication: 2
linked author: Kagan, Jonathan
linked information resource: Innate Immune Receptors as Competitive Determinants of Cell Fate.

Innate Immune Receptors as Competitive Determinants of Cell Fate.
PubMed Identifier: 28622520
author list: Franz KM, Kagan JC
published in: Molecular cell
information resource reference: Innate Immune Receptors as Competitive Determinants of Cell Fate. Mol Cell. 2017 Jun 15; 66(6):750-760.
journal title abbreviation: Mol Cell
publication date: 2017-06-15T00:00:00
year: 2017
type: Academic Article
type: Article
type: Document
type: Information Resource

Psychiatric correlates of behavioral inhibition in young children of parents with and without psychiatric disorders.
PubMed Identifier: 2294852
author list: Biederman J, Rosenbaum JF, Hirshfeld DR, Faraone SV, Bolduc EA, Gersten M, Meminger SR, Kagan J, Snidman N, Reznick JS
published in: Archives of general psychiatry
information resource reference: Psychiatric correlates of behavioral inhibition in young children of parents with and without psychiatric disorders. Arch Gen Psychiatry. 1990 Jan; 47(1):21-6.
journal title abbreviation: Arch Gen Psychiatry
publication date: 1990-01-01T00:00:00
year: 1990
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 990858
type: Authorship
author rank in publication: 2
linked author: Kagan, Jonathan
linked information resource: Apoptosis and Necroptosis as Host Defense Strategies to Prevent Viral Infection.

Apoptosis and Necroptosis as Host Defense Strategies to Prevent Viral Infection.
PubMed Identifier: 28642032
author list: Orzalli MH, Kagan JC
published in: Trends in cell biology
information resource reference: Apoptosis and Necroptosis as Host Defense Strategies to Prevent Viral Infection. Trends Cell Biol. 2017 11; 27(11):800-809.
journal title abbreviation: Trends Cell Biol
publication date: 2017-06-19T00:00:00
year: 2017
type: Academic Article
type: Article
type: Document
type: Information Resource

Immunophenotypic markers and antiretroviral therapy (IMART): T cell activation and maturation help predict treatment response.
PubMed Identifier: 15122517
author list: Mildvan D, Bosch RJ, Kim RS, Spritzler J, Haas DW, Kuritzkes D, Kagan J, Nokta M, DeGruttola V, Moreno M, Landay A
published in: The Journal of infectious diseases
information resource reference: Immunophenotypic markers and antiretroviral therapy (IMART): T cell activation and maturation help predict treatment response. J Infect Dis. 2004 May 15; 189(10):1811-20.
journal title abbreviation: J Infect Dis
publication date: 2004-04-29T00:00:00
year: 2004
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 996435
type: Authorship
author rank in publication: 5
linked author: Kagan, Jonathan
linked information resource: Environmental Stress Causes Lethal Neuro-Trauma during Asymptomatic Viral Infections.

Environmental Stress Causes Lethal Neuro-Trauma during Asymptomatic Viral Infections.
PubMed Identifier: 28704652
author list: Chow J, Márka Z, Bartos I, Márka S, Kagan JC
published in: Cell host & microbe
information resource reference: Environmental Stress Causes Lethal Neuro-Trauma during Asymptomatic Viral Infections. Cell Host Microbe. 2017 Jul 12; 22(1):48-60.e5.
journal title abbreviation: Cell Host Microbe
publication date: 2017-07-12T00:00:00
year: 2017
type: Academic Article
type: Article
type: Document
type: Information Resource

300 Longwood Ave
type: Address
address line 1: Childrens Hospital
address line 2: Enders 649
address line 3: 300 Longwood Ave
city: Boston
postal code: 02115
state or province: MA

Deciphering the function of nucleic acid sensing TLRs one regulatory step at a time.
PubMed Identifier: 21622162
author list: Marek LR, Kagan JC
published in: Frontiers in bioscience (Landmark edition)
information resource reference: Deciphering the function of nucleic acid sensing TLRs one regulatory step at a time. Front Biosci (Landmark Ed). 2011 06 01; 16(6):2060-8.
journal title abbreviation: Front Biosci (Landmark Ed)
publication date: 2011-06-01T00:00:00
year: 2011
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1004562
type: Authorship
author rank in publication: 2
linked author: Kagan, Jonathan
linked information resource: A one-protein signaling pathway in the innate immune system.

Authorship 1004409
type: Authorship
author rank in publication: 2
linked author: Kagan, Jonathan
linked information resource: Multi-receptor detection of individual bacterial products by the innate immune system.

A one-protein signaling pathway in the innate immune system.
PubMed Identifier: 28783697
author list: Orzalli MH, Kagan JC
published in: Science immunology
information resource reference: A one-protein signaling pathway in the innate immune system. Sci Immunol. 2016 Aug 19; 1(2):eaah6184.
journal title abbreviation: Sci Immunol
publication date: 2016-08-19T00:00:00
year: 2016
type: Academic Article
type: Article
type: Document
type: Information Resource

Multi-receptor detection of individual bacterial products by the innate immune system.
PubMed Identifier: 28461704
author list: Kieser KJ, Kagan JC
published in: Nature reviews. Immunology
information resource reference: Multi-receptor detection of individual bacterial products by the innate immune system. Nat Rev Immunol. 2017 Jun; 17(6):376-390.
journal title abbreviation: Nat Rev Immunol
publication date: 2017-05-02T00:00:00
year: 2017
type: Academic Article
type: Article
type: Document
type: Information Resource

https://connects.catalyst.harvard.edu/Profiles/profile/881155
PubMed Identifier: 7680972
author list: Gelman R, Cheng SC, Kidd P, Waxdal M, Kagan J
published in: Clinical immunology and immunopathology
information resource reference: Assessment of the effects of instrumentation, monoclonal antibody, and fluorochrome on flow cytometric immunophenotyping: a report based on 2 years of the NIAID DAIDS flow cytometry quality assessment program. Clin Immunol Immunopathol. 1993 Feb; 66(2):150-62.
journal title abbreviation: Clin Immunol Immunopathol
publication date: 1993-02-01T00:00:00
year: 1993
type: Academic Article
type: Article
type: Document
type: Information Resource
label: Assessment of the effects of instrumentation, monoclonal antibody, and fluorochrome on flow cytometric immunophenotyping: a report based on 2 years of the NIAID DAIDS flow cytometry quality assessment program.

MyD88-dependent TLR1/2 signals educate dendritic cells with gut-specific imprinting properties.
PubMed Identifier: 21646294
author list: Wang S, Villablanca EJ, De Calisto J, Gomes DC, Nguyen DD, Mizoguchi E, Kagan JC, Reinecker HC, Hacohen N, Nagler C, Xavier RJ, Rossi-Bergmann B, Chen YB, Blomhoff R, Snapper SB, Mora JR
published in: Journal of immunology (Baltimore, Md. : 1950)
information resource reference: MyD88-dependent TLR1/2 signals educate dendritic cells with gut-specific imprinting properties. J Immunol. 2011 Jul 01; 187(1):141-50.
journal title abbreviation: J Immunol
publication date: 2011-06-06T00:00:00
year: 2011
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1014340
type: Authorship
author rank in publication: 3
linked author: Kagan, Jonathan
linked information resource: Type III IFNs Are Commonly Induced by Bacteria-Sensing TLRs and Reinforce Epithelial Barriers during Infection.

Type III IFNs Are Commonly Induced by Bacteria-Sensing TLRs and Reinforce Epithelial Barriers during Infection.
PubMed Identifier: 28954888
author list: Odendall C, Voak AA, Kagan JC
published in: Journal of immunology (Baltimore, Md. : 1950)
information resource reference: Type III IFNs Are Commonly Induced by Bacteria-Sensing TLRs and Reinforce Epithelial Barriers during Infection. J Immunol. 2017 11 01; 199(9):3270-3279.
journal title abbreviation: J Immunol
publication date: 2017-09-27T00:00:00
year: 2017
type: Academic Article
type: Article
type: Document
type: Information Resource

NIAID Division of AIDS flow cytometry quality assessment program.
PubMed Identifier: 8494245
author list: Kagan J, Gelman R, Waxdal M, Kidd P
published in: Annals of the New York Academy of Sciences
information resource reference: NIAID Division of AIDS flow cytometry quality assessment program. Ann N Y Acad Sci. 1993 Mar 20; 677:50-2.
journal title abbreviation: Ann N Y Acad Sci
publication date: 1993-03-20T00:00:00
year: 1993
type: Academic Article
type: Article
type: Document
type: Information Resource

Legionella subvert the functions of Rab1 and Sec22b to create a replicative organelle.
PubMed Identifier: 15117975
author list: Kagan JC, Stein MP, Pypaert M, Roy CR
published in: The Journal of experimental medicine
information resource reference: Legionella subvert the functions of Rab1 and Sec22b to create a replicative organelle. J Exp Med. 2004 May 03; 199(9):1201-11.
journal title abbreviation: J Exp Med
publication date: 2004-04-26T00:00:00
year: 2004
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1019373
type: Authorship
author rank in publication: 2
linked author: Kagan, Jonathan
linked information resource: How Inflammasomes Inform Adaptive Immunity.

Authorship 1019050
type: Authorship
author rank in publication: 5
linked author: Kagan, Jonathan
linked information resource: By Capturing Inflammatory Lipids Released from Dying Cells, the Receptor CD14 Induces Inflammasome-Dependent Phagocyte Hyperactivation.

How Inflammasomes Inform Adaptive Immunity.
PubMed Identifier: 28987733
author list: Evavold CL, Kagan JC
published in: Journal of molecular biology
information resource reference: How Inflammasomes Inform Adaptive Immunity. J Mol Biol. 2018 01 19; 430(2):217-237.
journal title abbreviation: J Mol Biol
publication date: 2017-10-05T00:00:00
year: 2017
type: Academic Article
type: Article
type: Document
type: Information Resource

By Capturing Inflammatory Lipids Released from Dying Cells, the Receptor CD14 Induces Inflammasome-Dependent Phagocyte Hyperactivation.
PubMed Identifier: 29045901
author list: Zanoni I, Tan Y, Di Gioia M, Springstead JR, Kagan JC
published in: Immunity
information resource reference: By Capturing Inflammatory Lipids Released from Dying Cells, the Receptor CD14 Induces Inflammasome-Dependent Phagocyte Hyperactivation. Immunity. 2017 10 17; 47(4):697-709.e3.
journal title abbreviation: Immunity
publication date: 2017-10-17T00:00:00
year: 2017
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1022562
type: Authorship
author rank in publication: 4
linked author: Kagan, Jonathan
linked information resource: Expression and function of gamma delta- and alpha beta-T cell receptor heterodimers on human somatic T cell hybrids.

Authorship 1022605
type: Authorship
author rank in publication: 3
linked author: Kagan, Jonathan
linked information resource: In vivo activity of affinity-purified helper factor from antigen-specific helper clone.

In vivo activity of affinity-purified helper factor from antigen-specific helper clone.
PubMed Identifier: 2578517
author list: Azar Y, Falek PR, Kagan J, Ben-Sasson SZ
published in: Journal of immunology (Baltimore, Md. : 1950)
information resource reference: In vivo activity of affinity-purified helper factor from antigen-specific helper clone. J Immunol. 1985 Mar; 134(3):1717-22.
journal title abbreviation: J Immunol
publication date: 1985-03-01T00:00:00
year: 1985
type: Academic Article
type: Article
type: Document
type: Information Resource

Expression and function of gamma delta- and alpha beta-T cell receptor heterodimers on human somatic T cell hybrids.
PubMed Identifier: 1692058
author list: Kozbor D, Cassatella MA, Lessin S, Kagan J, Finver S, Faust J, Trinchieri G, Croce CM
published in: Journal of immunology (Baltimore, Md. : 1950)
information resource reference: Expression and function of gamma delta- and alpha beta-T cell receptor heterodimers on human somatic T cell hybrids. J Immunol. 1990 May 15; 144(10):3677-83.
journal title abbreviation: J Immunol
publication date: 1990-05-15T00:00:00
year: 1990
type: Academic Article
type: Article
type: Document
type: Information Resource

Three-color supplement to the NIAID DAIDS guideline for flow cytometric immunophenotyping.
PubMed Identifier: 8889396
author list: Nicholson J, Kidd P, Mandy F, Livnat D, Kagan J
published in: Cytometry
information resource reference: Three-color supplement to the NIAID DAIDS guideline for flow cytometric immunophenotyping. Cytometry. 1996 Sep 15; 26(3):227-30.
journal title abbreviation: Cytometry
publication date: 1996-09-15T00:00:00
year: 1996
type: Academic Article
type: Article
type: Document
type: Information Resource

Impact of tic disorders on ADHD outcome across the life cycle: findings from a large group of adults with and without ADHD.
PubMed Identifier: 11282697
author list: Spencer TJ, Biederman J, Faraone S, Mick E, Coffey B, Geller D, Kagan J, Bearman SK, Wilens T
published in: The American journal of psychiatry
information resource reference: Impact of tic disorders on ADHD outcome across the life cycle: findings from a large group of adults with and without ADHD. Am J Psychiatry. 2001 Apr; 158(4):611-7.
journal title abbreviation: Am J Psychiatry
publication date: 2001-04-01T00:00:00
year: 2001
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1030196
type: Authorship
author rank in publication: 6
linked author: Kagan, Jonathan
linked information resource: The Pore-Forming Protein Gasdermin D Regulates Interleukin-1 Secretion from Living Macrophages.

Authorship 1030106
type: Authorship
author rank in publication: 2
linked author: Kagan, Jonathan
linked information resource: Biochemical Isolation of the Myddosome from Murine Macrophages.

Biochemical Isolation of the Myddosome from Murine Macrophages.
PubMed Identifier: 29177857
author list: Tan Y, Kagan JC
published in: Methods in molecular biology (Clifton, N.J.)
information resource reference: Biochemical Isolation of the Myddosome from Murine Macrophages. Methods Mol Biol. 2018; 1714:79-95.
journal title abbreviation: Methods Mol Biol
publication date: 2018-01-01T00:00:00
year: 2018
type: Academic Article
type: Article
type: Document
type: Information Resource

The Pore-Forming Protein Gasdermin D Regulates Interleukin-1 Secretion from Living Macrophages.
PubMed Identifier: 29195811
author list: Evavold CL, Ruan J, Tan Y, Xia S, Wu H, Kagan JC
published in: Immunity
information resource reference: The Pore-Forming Protein Gasdermin D Regulates Interleukin-1 Secretion from Living Macrophages. Immunity. 2018 01 16; 48(1):35-44.e6.
journal title abbreviation: Immunity
publication date: 2017-11-28T00:00:00
year: 2017
type: Academic Article
type: Article
type: Document
type: Information Resource

Analysis of Rab1 recruitment to vacuoles containing Legionella pneumophila.
PubMed Identifier: 16473578
author list: Kagan JC, Murata T, Roy CR
published in: Methods in enzymology
information resource reference: Analysis of Rab1 recruitment to vacuoles containing Legionella pneumophila. Methods Enzymol. 2005; 403:71-81.
journal title abbreviation: Methods Enzymol
publication date: 2005-01-01T00:00:00
year: 2005
type: Academic Article
type: Article
type: Document
type: Information Resource

Phosphoinositide-mediated adaptor recruitment controls Toll-like receptor signaling.
PubMed Identifier: 16751103
author list: Kagan JC, Medzhitov R
published in: Cell
information resource reference: Phosphoinositide-mediated adaptor recruitment controls Toll-like receptor signaling. Cell. 2006 Jun 02; 125(5):943-55.
journal title abbreviation: Cell
publication date: 2006-06-02T00:00:00
year: 2006
type: Academic Article
type: Article
type: Document
type: Information Resource

Polymorphisms in toll-like receptor 4 underlie susceptibility to tumor induction by the mouse polyomavirus.
PubMed Identifier: 22896604
author list: Velupillai P, Sung CK, Andrews E, Moran J, Beier D, Kagan J, Benjamin T
published in: Journal of virology
information resource reference: Polymorphisms in toll-like receptor 4 underlie susceptibility to tumor induction by the mouse polyomavirus. J Virol. 2012 Nov; 86(21):11541-7.
journal title abbreviation: J Virol
publication date: 2012-08-15T00:00:00
year: 2012
type: Academic Article
type: Article
type: Document
type: Information Resource

Selective modulation of TLR4-activated inflammatory responses by altered iron homeostasis in mice.
PubMed Identifier: 19809161
author list: Wang L, Harrington L, Trebicka E, Shi HN, Kagan JC, Hong CC, Lin HY, Babitt JL, Cherayil BJ
published in: The Journal of clinical investigation
information resource reference: Selective modulation of TLR4-activated inflammatory responses by altered iron homeostasis in mice. J Clin Invest. 2009 Nov; 119(11):3322-8.
journal title abbreviation: J Clin Invest
publication date: 2009-10-05T00:00:00
year: 2009
type: Academic Article
type: Article
type: Document
type: Information Resource

https://connects.catalyst.harvard.edu/Profiles/profile/974303
PubMed Identifier: 8648205
author list: Valentine FT, Kundu S, Haslett PA, Katzenstein D, Beckett L, Spino C, Borucki M, Vasquez M, Smith G, Korvick J, Kagan J, Merigan TC
published in: The Journal of infectious diseases
information resource reference: A randomized, placebo-controlled study of the immunogenicity of human immunodeficiency virus (HIV) rgp160 vaccine in HIV-infected subjects with > or = 400/mm3 CD4 T lymphocytes (AIDS Clinical Trials Group Protocol 137). J Infect Dis. 1996 Jun; 173(6):1336-46.
journal title abbreviation: J Infect Dis
publication date: 1996-06-01T00:00:00
year: 1996
type: Academic Article
type: Article
type: Document
type: Information Resource
label: A randomized, placebo-controlled study of the immunogenicity of human immunodeficiency virus (HIV) rgp160 vaccine in HIV-infected subjects with > or = 400/mm3 CD4 T lymphocytes (AIDS Clinical Trials Group Protocol 137).

An approach to the validation of markers for use in AIDS clinical trials.
PubMed Identifier: 9142767
author list: Mildvan D, Landay A, De Gruttola V, Machado SG, Kagan J
published in: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
information resource reference: An approach to the validation of markers for use in AIDS clinical trials. Clin Infect Dis. 1997 May; 24(5):764-74.
journal title abbreviation: Clin Infect Dis
publication date: 1997-05-01T00:00:00
year: 1997
type: Academic Article
type: Article
type: Document
type: Information Resource

Behavioral inhibition in childhood: a risk factor for anxiety disorders.
PubMed Identifier: 9384823
author list: Rosenbaum JF, Biederman J, Bolduc-Murphy EA, Faraone SV, Chaloff J, Hirshfeld DR, Kagan J
published in: Harvard review of psychiatry
information resource reference: Behavioral inhibition in childhood: a risk factor for anxiety disorders. Harv Rev Psychiatry. 1993 May-Jun; 1(1):2-16.
journal title abbreviation: Harv Rev Psychiatry
publication date: 1993-05-01T00:00:00
year: 1993
type: Academic Article
type: Article
type: Document
type: Information Resource

Further evidence of an association between behavioral inhibition and anxiety disorders: results from a family study of children from a non-clinical sample.
PubMed Identifier: 2027095
author list: Rosenbaum JF, Biederman J, Hirshfeld DR, Bolduc EA, Faraone SV, Kagan J, Snidman N, Reznick JS
published in: Journal of psychiatric research
information resource reference: Further evidence of an association between behavioral inhibition and anxiety disorders: results from a family study of children from a non-clinical sample. J Psychiatr Res. 1991; 25(1-2):49-65.
journal title abbreviation: J Psychiatr Res
publication date: 1991-01-01T00:00:00
year: 1991
type: Academic Article
type: Article
type: Document
type: Information Resource

Signaling organelles of the innate immune system.
PubMed Identifier: 23217704
author list: Kagan JC
published in: Cell
information resource reference: Signaling organelles of the innate immune system. Cell. 2012 Dec 07; 151(6):1168-78.
journal title abbreviation: Cell
publication date: 2012-12-07T00:00:00
year: 2012
type: Academic Article
type: Article
type: Document
type: Information Resource

Genetic association analysis of behavioral inhibition using candidate loci from mouse models.
PubMed Identifier: 11353440
author list: Smoller JW, Rosenbaum JF, Biederman J, Susswein LS, Kennedy J, Kagan J, Snidman N, Laird N, Tsuang MT, Faraone SV, Schwarz A, Slaugenhaupt SA
published in: American journal of medical genetics
information resource reference: Genetic association analysis of behavioral inhibition using candidate loci from mouse models. Am J Med Genet. 2001 Apr 08; 105(3):226-35.
journal title abbreviation: Am J Med Genet
publication date: 2001-04-08T00:00:00
year: 2001
type: Academic Article
type: Article
type: Document
type: Information Resource

Efficacy of a mixed amphetamine salts compound in adults with attention-deficit/hyperactivity disorder.
PubMed Identifier: 11483144
author list: Spencer T, Biederman J, Wilens T, Faraone S, Prince J, Gerard K, Doyle R, Parekh A, Kagan J, Bearman SK
published in: Archives of general psychiatry
information resource reference: Efficacy of a mixed amphetamine salts compound in adults with attention-deficit/hyperactivity disorder. Arch Gen Psychiatry. 2001 Aug; 58(8):775-82.
journal title abbreviation: Arch Gen Psychiatry
publication date: 2001-08-01T00:00:00
year: 2001
type: Academic Article
type: Article
type: Document
type: Information Resource

Legionella phagosomes intercept vesicular traffic from endoplasmic reticulum exit sites.
PubMed Identifier: 12447391
author list: Kagan JC, Roy CR
published in: Nature cell biology
information resource reference: Legionella phagosomes intercept vesicular traffic from endoplasmic reticulum exit sites. Nat Cell Biol. 2002 Dec; 4(12):945-54.
journal title abbreviation: Nat Cell Biol
publication date: 2002-12-01T00:00:00
year: 2002
type: Academic Article
type: Article
type: Document
type: Information Resource