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bFGF-induced alterations in cellular markers of senescence in growth-rescued fibroblasts from chronic venous ulcer and venous reflux patients. Ann Vasc Surg. 2003 May; 17(3):239-44.
bFGF-induced alterations in cellular markers of senescence in growth-rescued fibroblasts from chronic venous ulcer and venous reflux patients.
Pathophysiology of Chronic Venous Disease and Venous Ulcers. Surg Clin North Am. 2018 Apr; 98(2):337-347.
Pathophysiology of Chronic Venous Disease and Venous Ulcers.
Ebaugh JL, Gagnon D, Owens CD, Conte MS, Raffetto JD
Comparison of costs of staged versus simultaneous lower extremity arterial hybrid procedures. Am J Surg. 2008 Nov; 196(5):634-40.
Comparison of costs of staged versus simultaneous lower extremity arterial hybrid procedures.
Pojoga LH, Yao TM, Sinha S, Ross RL, Lin JC, Raffetto JD, Adler GK, Williams GH, Khalil RA
American journal of physiology. Heart and circulatory physiology
Effect of dietary sodium on vasoconstriction and eNOS-mediated vascular relaxation in caveolin-1-deficient mice. Am J Physiol Heart Circ Physiol. 2008 Mar; 294(3):H1258-65.
Effect of dietary sodium on vasoconstriction and eNOS-mediated vascular relaxation in caveolin-1-deficient mice.
Raffetto JD, Mendez MV, Marien BJ, Byers HR, Phillips TJ, Park HY, Menzoian JO
Changes in cellular motility and cytoskeletal actin in fibroblasts from patients with chronic venous insufficiency and in neonatal fibroblasts in the presence of chronic wound fluid. J Vasc Surg. 2001 Jun; 33(6):1233-41.
Changes in cellular motility and cytoskeletal actin in fibroblasts from patients with chronic venous insufficiency and in neonatal fibroblasts in the presence of chronic wound fluid.
Raffetto JD, Barros YV, Wells AK, Khalil RA
MMP-2 induced vein relaxation via inhibition of [Ca2+]e-dependent mechanisms of venous smooth muscle contraction. Role of RGD peptides. J Surg Res. 2010 Apr; 159(2):755-64.
MMP-2 induced vein relaxation via inhibition of [Ca2+]e-dependent mechanisms of venous smooth muscle contraction. Role of RGD peptides.
Lim CS, Qiao X, Reslan OM, Xia Y, Raffetto JD, Paleolog E, Davies AH, Khalil RA
Prolonged mechanical stretch is associated with upregulation of hypoxia-inducible factors and reduced contraction in rat inferior vena cava. J Vasc Surg. 2011 Mar; 53(3):764-73.
Prolonged mechanical stretch is associated with upregulation of hypoxia-inducible factors and reduced contraction in rat inferior vena cava.
Venous ulcer: what is new? Plast Reconstr Surg. 2011 Jan; 127 Suppl 1:279S-288S.
Mendez MV, Raffetto JD, Phillips T, Menzoian JO, Park HY
The proliferative capacity of neonatal skin fibroblasts is reduced after exposure to venous ulcer wound fluid: A potential mechanism for senescence in venous ulcers. J Vasc Surg. 1999 Oct; 30(4):734-43.
The proliferative capacity of neonatal skin fibroblasts is reduced after exposure to venous ulcer wound fluid: A potential mechanism for senescence in venous ulcers.
Ebaugh JL, Yuan M, Hu J, Chen A, Raffetto JD
Intimal sarcoma of the superficial femoral artery with osteosarcomatous differentiation. J Vasc Surg. 2011 May; 53(5):1394-7.
Intimal sarcoma of the superficial femoral artery with osteosarcomatous differentiation.
European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery
Commentary on: 'In vitro identification of distinctive metabolic signatures of intact varicose vein tissue via magic angle spinning nuclear magnetic resonance spectroscopy'. Eur J Vasc Endovasc Surg. 2012 Oct; 44(4):451.
Commentary on: 'In vitro identification of distinctive metabolic signatures of intact varicose vein tissue via magic angle spinning nuclear magnetic resonance spectroscopy'.
Pojoga LH, Williams JS, Yao TM, Kumar A, Raffetto JD, do Nascimento GR, Reslan OM, Adler GK, Williams GH, Shi Y, Khalil RA
Histone demethylase LSD1 deficiency during high-salt diet is associated with enhanced vascular contraction, altered NO-cGMP relaxation pathway, and hypertension. Am J Physiol Heart Circ Physiol. 2011 Nov; 301(5):H1862-71.
Histone demethylase LSD1 deficiency during high-salt diet is associated with enhanced vascular contraction, altered NO-cGMP relaxation pathway, and hypertension.
Matrix metalloproteinases and their inhibitors in vascular remodeling and vascular disease. Biochem Pharmacol. 2008 Jan 15; 75(2):346-59.
Matrix metalloproteinases and their inhibitors in vascular remodeling and vascular disease.
Ca(2+)-dependent contraction by the saponoside escin in rat vena cava: implications in venotonic treatment of varicose veins. J Vasc Surg. 2011 Aug; 54(2):489-96.
Ca(2+)-dependent contraction by the saponoside escin in rat vena cava: implications in venotonic treatment of varicose veins.
Dermal pathology, cellular biology, and inflammation in chronic venous disease. Thromb Res. 2009; 123 Suppl 4:S66-71.
Dermal pathology, cellular biology, and inflammation in chronic venous disease.
Robert R. Linton, MD Professor of Surgery in the Field of Vascular and Endovascular Surgery
Invited commentary. J Vasc Surg. 2019 05; 69(5):1589-1590.
Superficial thrombophlebitis in varicose vein disease: the particular role of methylenetetrahydrofolate reductase. Phlebology. 2011 Jun; 26(4):133-4.
Superficial thrombophlebitis in varicose vein disease: the particular role of methylenetetrahydrofolate reductase.
Mechanisms of varicose vein formation: valve dysfunction and wall dilation. Phlebology. 2008; 23(2):85-98.
Mechanisms of varicose vein formation: valve dysfunction and wall dilation.
Seidman C, Raffetto JD, Overman KC, Menzoian JO
Venous ulcer fibroblasts respond to basic fibroblast growth factor at the cell cycle protein level. Ann Vasc Surg. 2006 May; 20(3):376-80.
Venous ulcer fibroblasts respond to basic fibroblast growth factor at the cell cycle protein level.
Raffetto JD, Yu P, Reslan OM, Xia Y, Khalil RA
Endothelium-dependent nitric oxide and hyperpolarization-mediated venous relaxation pathways in rat inferior vena cava. J Vasc Surg. 2012 Jun; 55(6):1716-25.
Endothelium-dependent nitric oxide and hyperpolarization-mediated venous relaxation pathways in rat inferior vena cava.
Gianesini S, Mosti G, Sibilla MG, Maietti E, Diaz JA, Raffetto JD, Zamboni P, Menegatti E
Journal of vascular surgery. Venous and lymphatic disorders
Lower limb volume in healthy individuals after walking with compression stockings. J Vasc Surg Venous Lymphat Disord. 2019 07; 7(4):557-561.
Lower limb volume in healthy individuals after walking with compression stockings.
Raffetto JD, Calanni F, Mattana P, Khalil RA
Sulodexide promotes arterial relaxation via endothelium-dependent nitric oxide-mediated pathway. Biochem Pharmacol. 2019 08; 166:347-356.
Sulodexide promotes arterial relaxation via endothelium-dependent nitric oxide-mediated pathway.
Columbo JA, Kang R, Spangler EL, Newhall K, Brooke BS, Dosluoglu H, Lee ES, Raffetto JD, Henke PK, Tang GS, Mureebe L, Kougias P, Johanning J, Arya S, Scali ST, Stone DH, Suckow BD, Orion K, Halpern V, O'Connell J, Inhat D, Nelson P, Tzeng E, Zhou W, Barry M, Sirovich B, Goodney PP
Design of the PReferences for Open Versus Endovascular Repair of Abdominal Aortic Aneurysm (PROVE-AAA) Trial. Ann Vasc Surg. 2020 May; 65:247-253.
Design of the PReferences for Open Versus Endovascular Repair of Abdominal Aortic Aneurysm (PROVE-AAA) Trial.
Jolissaint JS, Shah SK, Martin MC, Raffetto JD, McPhee JT
Risk prediction of 30-day mortality after lower extremity major amputation. J Vasc Surg. 2019 12; 70(6):1868-1876.
Risk prediction of 30-day mortality after lower extremity major amputation.
George H. A. Clowes, Jr. Professor of Surgery
Anderson PB, Wanken ZJ, Perri JL, Columbo JA, Kang R, Spangler EL, Newhall K, Brooke BS, Dosluoglu H, Lee ES, Raffetto JD, Henke PK, Tang GL, Mureebe L, Kougias P, Johanning J, Arya S, Scali ST, Stone DH, Suckow BD, Orion K, Halpern V, O'Connell J, Inhat D, Nelson P, Tzeng E, Zhou W, Barry M, Sirovich B, Goodney PP
Patient information sources when facing repair of abdominal aortic aneurysm. J Vasc Surg. 2020 02; 71(2):497-504.
Patient information sources when facing repair of abdominal aortic aneurysm.
Gianesini S, Mosti G, Raffetto JD, Maietti E, Chi YW, Tangerini L, Menegatti E
Case-control evaluation of the impact of below 20?mmHg elastic compression stockings on lower limb volume serial variations in standardized flights. Phlebology. 2020 Apr; 35(3):199-206.
Case-control evaluation of the impact of below 20?mmHg elastic compression stockings on lower limb volume serial variations in standardized flights.
Gianesini S, Obi A, Onida S, Baccellieri D, Bissacco D, Borsuk D, Campisi C, Campisi CC, Cavezzi A, Chi YW, Chunga J, Corda D, Crippa A, Davies A, De Maeseneer M, Diaz J, Ferreira J, Gasparis A, Intriago E, Jawien A, Jindal R, Kabnick L, Latorre A, Lee BB, Liew NC, Lurie F, Meissner M, Menegatti E, Molteni M, Morrison N, Mosti G, Narayanan S, Pannier F, Parsi K, Partsch H, Rabe E, Raffetto J, Raymond-Martimbeau P, Rockson S, Rosukhovski D, Santiago FR, Schul A, Schul M, Shaydakov E, Sibilla MG, Tessari L, Tomaselli F, Urbanek T, van Rijn MJ, Wakefield T, Wittens C, Zamboni P, Bottini O
Global guidelines trends and controversies in lower limb venous and lymphatic disease: Narrative literature revision and experts' opinions following the vWINter international meeting in Phlebology, Lymphology & Aesthetics, 23-25 January 2019. Phlebology. 2019 Sep; 34(1 Suppl):4-66.
Global guidelines trends and controversies in lower limb venous and lymphatic disease: Narrative literature revision and experts' opinions following the vWINter international meeting in Phlebology, Lymphology & Aesthetics, 23-25 January 2019.
Raffetto JD, Yu W, Wang X, Calanni F, Mattana P, Khalil RA
Sulodexide Improves Contraction and Decreases Matrix Metalloproteinase-2 and -9 in Veins Under Prolonged Stretch. J Cardiovasc Pharmacol. 2020 03; 75(3):211-221.
Sulodexide Improves Contraction and Decreases Matrix Metalloproteinase-2 and -9 in Veins Under Prolonged Stretch.
Understanding venous thrombosis pathways to effect pharmacologic treatment and resolution of venous thrombosis without increasing bleeding risk. J Vasc Surg Venous Lymphat Disord. 2020 03; 8(2):279.
Understanding venous thrombosis pathways to effect pharmacologic treatment and resolution of venous thrombosis without increasing bleeding risk.
Gianesini S, Raffetto JD, Mosti G, Maietti E, Sibilla MG, Zamboni P, Menegatti E
Volume control of the lower limb with graduated compression during different muscle pump activation conditions and the relation to limb circumference variation. J Vasc Surg Venous Lymphat Disord. 2020 09; 8(5):814-820.
Volume control of the lower limb with graduated compression during different muscle pump activation conditions and the relation to limb circumference variation.
Surgical spine stabilization and its association with iliac vein obstruction. J Vasc Surg Venous Lymphat Disord. 2020 05; 8(3):412.
Surgical spine stabilization and its association with iliac vein obstruction.
Raffetto JD, Ligi D, Maniscalco R, Khalil RA, Mannello F
Why Venous Leg Ulcers Have Difficulty Healing: Overview on Pathophysiology, Clinical Consequences, and Treatment. J Clin Med. 2020 Dec 24; 10(1).
Why Venous Leg Ulcers Have Difficulty Healing: Overview on Pathophysiology, Clinical Consequences, and Treatment.
Shaydakov ME, Ting W, Sadek M, Aziz F, Diaz JA, Raffetto JD, Marston WA, Lal BK, Welch HJ
Review of the current evidence for topical treatment for venous leg ulcers. J Vasc Surg Venous Lymphat Disord. 2022 01; 10(1):241-247.e15.
Review of the current evidence for topical treatment for venous leg ulcers.
Mechanisms of Lower Extremity Vein Dysfunction in Chronic Venous Disease and Implications in Management of Varicose Veins. Vessel Plus. 2021; 5.
Mechanisms of Lower Extremity Vein Dysfunction in Chronic Venous Disease and Implications in Management of Varicose Veins.
The novel and exciting research of E-selectin inhibition for deep venous thrombosis. J Vasc Surg Venous Lymphat Disord. 2022 01; 10(1):221.
The novel and exciting research of E-selectin inhibition for deep venous thrombosis.
Lurie F, Malgor RD, Carman T, Dean SM, Iafrati MD, Khilnani NM, Labropoulos N, Maldonado TS, Mortimer P, O'Donnell TF, Raffetto JD, Rockson SG, Gasparis AP
The American Venous Forum, American Vein and Lymphatic Society and the Society for Vascular Medicine expert opinion consensus on lymphedema diagnosis and treatment. Phlebology. 2022 May; 37(4):252-266.
The American Venous Forum, American Vein and Lymphatic Society and the Society for Vascular Medicine expert opinion consensus on lymphedema diagnosis and treatment.
Forsyth A, Carlson S, Martin M, Raffetto J, Alfson D, McPhee J
Late type III endoleaks are common in early generation Endologix AFX stent grafts. J Vasc Surg. 2022 09; 76(3):680-687.
Late type III endoleaks are common in early generation Endologix AFX stent grafts.
Reslan OM, McPhee JT, Brener BJ, Row HT, Eberhardt RT, Raffetto JD
Peri-Procedural Management of Hemodynamic Instability in Patients Undergoing Carotid Revascularization. Ann Vasc Surg. 2022 Sep; 85:406-417.
Peri-Procedural Management of Hemodynamic Instability in Patients Undergoing Carotid Revascularization.
Eid MA, Barnes JA, Mehta K, Wanken Z, Columbo J, Kang R, Newhall K, Halpern V, Raffetto J, Kougias P, Henke P, Tang G, Mureebe L, Johanning J, Tzeng E, Scali S, Stone D, Suckow B, Lee E, Arya S, Orion K, O'Connell J, Brooke B, Ihnat D, Dosluoglu H, Zhou W, Nelson P, Spangler E, Barry M, Sirovich B, Goodney P
Factors associated with preference of choice of aortic aneurysm repair in the PReference for Open Versus Endovascular repair of AAA (PROVE-AAA) study. J Vasc Surg. 2022 12; 76(6):1556-1564.
Factors associated with preference of choice of aortic aneurysm repair in the PReference for Open Versus Endovascular repair of AAA (PROVE-AAA) study.
Eid MA, Barry MJ, Tang GL, Henke PK, Johanning JM, Tzeng E, Scali ST, Stone DH, Suckow BD, Lee ES, Arya S, Brooke BS, Nelson PR, Spangler EL, Murebee L, Dosluoglu HH, Raffetto JD, Kougais P, Brewster LP, Alabi O, Dardik A, Halpern VJ, O'Connell JB, Ihnat DM, Zhou W, Sirovich BE, Metha K, Moore KO, Voorhees A, Goodney PP
Effect of a Decision Aid on Agreement Between Patient Preferences and Repair Type for Abdominal Aortic Aneurysm: A Randomized Clinical Trial. JAMA Surg. 2022 09 01; 157(9):e222935.
Effect of a Decision Aid on Agreement Between Patient Preferences and Repair Type for Abdominal Aortic Aneurysm: A Randomized Clinical Trial.
Ozsvath K, Raffetto JD, Lindner E, Murphy EH
Venous compression syndromes in females: A descriptive review. Semin Vasc Surg. 2023 Dec; 36(4):550-559.
Venous compression syndromes in females: A descriptive review.
Xu K, Lin B, Collado L, Martin MC, Carlson SJ, Raffetto JD, McPhee JT
Predicting wound complications following lower extremity revascularization. J Vasc Surg. 2024 03; 79(3):642-650.e2.
Predicting wound complications following lower extremity revascularization.
Zielinski A, Jasinska-Suminska K, Breborowicz A, Kowalska K, Zabel M, Wysocka T, Khalil RA, Raffetto JD, Urbanek T
Changes of the serum properties and its effect on the endothelial cells restoration in patients with chronic venous disease treated with sulodexide. J Vasc Surg Venous Lymphat Disord. 2024 Sep; 12(5):101941.
Changes of the serum properties and its effect on the endothelial cells restoration in patients with chronic venous disease treated with sulodexide.
Lal BK, Mayorga-Carlin M, Sahoo S, Cambria R, Raffetto JD, Gasper W, Ju M, Macdonald S, Sorkin JD
Impact of the type of anesthesia on adverse events during transcarotid artery revascularization. J Vasc Surg. 2024 12; 80(6):1716-1726.e1.
Impact of the type of anesthesia on adverse events during transcarotid artery revascularization.
Invited commentary. J Vasc Surg. 2013 Aug; 58(2):426.
Mannello F, Medda V, Ligi D, Raffetto JD
Glycosaminoglycan sulodexide inhibition of MMP-9 gelatinase secretion and activity: possible pharmacological role against collagen degradation in vascular chronic diseases. Curr Vasc Pharmacol. 2013 May; 11(3):354-65.
Glycosaminoglycan sulodexide inhibition of MMP-9 gelatinase secretion and activity: possible pharmacological role against collagen degradation in vascular chronic diseases.
Inflammation in chronic venous ulcers. Phlebology. 2013 Mar; 28 Suppl 1:61-7.
Gloviczki ML, Stoughton J, Puggioni A, Gloviczki P, Raffetto JD
Utility of venoactive compounds in post-thrombotic syndrome: A systematic review. J Vasc Surg Venous Lymphat Disord. 2025 Jul; 13(4):102228.
Utility of venoactive compounds in post-thrombotic syndrome: A systematic review.
Figueroa AV, Cifuentes S, Ulloa JH, Raffetto J
Journal of vascular surgery cases and innovative techniques
Iliac venous stenting as adjunct in the management of symptomatic orthostatic hypotension in iliac vein compression. J Vasc Surg Cases Innov Tech. 2024 Dec; 10(6):101483.
Iliac venous stenting as adjunct in the management of symptomatic orthostatic hypotension in iliac vein compression.
Mannello F, Ligi D, Canale M, Raffetto JD
Sulodexide down-regulates the release of cytokines, chemokines, and leukocyte colony stimulating factors from human macrophages: role of glycosaminoglycans in inflammatory pathways of chronic venous disease. Curr Vasc Pharmacol. 2014 Jan; 12(1):173-85.
Sulodexide down-regulates the release of cytokines, chemokines, and leukocyte colony stimulating factors from human macrophages: role of glycosaminoglycans in inflammatory pathways of chronic venous disease.
Omics profiles in chronic venous ulcer wound fluid: innovative applications for translational medicine. Expert Rev Mol Diagn. 2014 Jul; 14(6):737-62.
Omics profiles in chronic venous ulcer wound fluid: innovative applications for translational medicine.
International angiology : a journal of the International Union of Angiology
Glycosaminoglycan sulodexide modulates inflammatory pathways in chronic venous disease. Int Angiol. 2014 Jun; 33(3):236-42.
Glycosaminoglycan sulodexide modulates inflammatory pathways in chronic venous disease.
Pathophysiology of chronic venous disease. Int Angiol. 2014 Jun; 33(3):212-21.
Pathophysiology of chronic venous disease.
Zauli G, Tisato V, Raffetto JD, Vaccarezza M
Inflammation and Cardiovascular Cross Talk in Ischemic Vascular Diseases. Mediators Inflamm. 2017; 2017:3161968.
Inflammation and Cardiovascular Cross Talk in Ischemic Vascular Diseases.
Pompilio G, Integlia D, Raffetto J, Palareti G
TH open : companion journal to thrombosis and haemostasis
Comparative Efficacy and Safety of Sulodexide and Other Extended Anticoagulation Treatments for Prevention of Recurrent Venous Thromboembolism: A Bayesian Network Meta-analysis. TH Open. 2020 Apr; 4(2):e80-e93.
Comparative Efficacy and Safety of Sulodexide and Other Extended Anticoagulation Treatments for Prevention of Recurrent Venous Thromboembolism: A Bayesian Network Meta-analysis.
Gianesini S, Rimondi E, Raffetto JD, Melloni E, Pellati A, Menegatti E, Avruscio GP, Bassetto F, Costa AL, Rockson S
Human collecting lymphatic glycocalyx identification by electron microscopy and immunohistochemistry. Sci Rep. 2023 02 21; 13(1):3022.
Human collecting lymphatic glycocalyx identification by electron microscopy and immunohistochemistry.
Gianesini S, Chi YW, Agüero C, Alqedrah D, Amore M, Barbati M, Baturone A, Black S, Borsuk D, Bottini O, Caprini J, Chamo M, Cherian M, Chernuka L, DE Maeseneer M, Diaz J, Garcia MJ, Gibson K, Gloviczki M, Gloviczki P, Golovina V, Goranova E, Grillo L, Gwozdz A, Hirsch T, Hussein E, Intriago E, Jalaie H, Jaworucka-Kaczorowska A, Jindal R, Josnin M, Khilnani NM, Kim DI, Latorre A, Lazarashvili Z, Lee BB, Leon L, Liew NC, Lobastov K, Lurie F, Maghetti A, Menegatti E, Miyake K, Mo M, Narayanan S, Neuhardt D, Pannier F, Prego A, Rabe E, Raffetto J, Raymond-Martimbeau P, Redman L, Reina-Gutierrez L, Rial R, Rockson S, Romanelli M, Santiago FR, Santiago RA, Sermsathanasawadi N, Shaydakov E, Simkin C, Sousa J, Stoughton J, Szuba A, Taha W, Ulloa J, Urbanek T, Vitale M, Vuylsteke M, Wang J, Weingartner J, Wilson S, Yamaki T, Ng Y, Zolotukhin I, Mansilha A
Fake-news-free evidence-based communication for proper vein-lymphatic disease management. Int Angiol. 2023 Apr; 42(2):89-189.
Fake-news-free evidence-based communication for proper vein-lymphatic disease management.
Gonzalez-Ochoa AJ, Raffetto JD, Hernández AG, Zavala N, Gutiérrez O, Vargas A, Loustaunau J
Sulodexide in the Treatment of Patients with Early Stages of COVID-19: A Randomized Controlled Trial. Thromb Haemost. 2021 07; 121(7):944-954.
Sulodexide in the Treatment of Patients with Early Stages of COVID-19: A Randomized Controlled Trial.
Chronic venous insufficiency. Circulation. 2014 Jul 22; 130(4):333-46.
O'Donnell TF, Passman MA, Marston WA, Ennis WJ, Dalsing M, Kistner RL, Lurie F, Henke PK, Gloviczki ML, Eklöf BG, Stoughton J, Raju S, Shortell CK, Raffetto JD, Partsch H, Pounds LC, Cummings ME, Gillespie DL, McLafferty RB, Murad MH, Wakefield TW, Gloviczki P
Management of venous leg ulcers: clinical practice guidelines of the Society for Vascular Surgery ® and the American Venous Forum. J Vasc Surg. 2014 Aug; 60(2 Suppl):3S-59S.
Management of venous leg ulcers: clinical practice guidelines of the Society for Vascular Surgery ® and the American Venous Forum.
Venous leg ulceration pathophysiology and evidence based treatment. Vasc Med. 2015 Apr; 20(2):168-81.
Venous leg ulceration pathophysiology and evidence based treatment.
Reslan OM, Raffetto JD, Addis M, Sundick S
Congenital Absence of Inferior Vena Cava in a Young Patient with Iliofemoral Deep Venous Thrombosis Treated with Ultrasound-accelerated Catheter-directed Thrombolysis: Case Report and Review of the Literature. Ann Vasc Surg. 2015 Nov; 29(8):1657.e9-15.
Congenital Absence of Inferior Vena Cava in a Young Patient with Iliofemoral Deep Venous Thrombosis Treated with Ultrasound-accelerated Catheter-directed Thrombolysis: Case Report and Review of the Literature.
Pathophysiology of wound healing and alterations in venous leg ulcers-review. Phlebology. 2016 Mar; 31(1 Suppl):56-62.
Pathophysiology of wound healing and alterations in venous leg ulcers-review.
Raffetto JD, Mosti G, Santi M, Ligi D, Mannello F
Matrix Metalloproteinase Profiles in Chronic Venous Ulcer Wound Fluid of Inflammatory and Granulating Venous Leg Ulcers. J Vasc Surg Venous Lymphat Disord. 2015 Jan; 3(1):119-20.
Matrix Metalloproteinase Profiles in Chronic Venous Ulcer Wound Fluid of Inflammatory and Granulating Venous Leg Ulcers.
Almeida J, Kabnick L, Wakefield T, Raffetto J, McLafferty R, Pappas P, Rectenwald J, Blebea J, Gillespie D, Onyeachom U, Kinsman R, Lal BK
Management Trends for Chronic Venous Insufficiency Across the United States: A Report from the American Venous Registry. J Vasc Surg Venous Lymphat Disord. 2013 Jan; 1(1):100.
Management Trends for Chronic Venous Insufficiency Across the United States: A Report from the American Venous Registry.
Invited Commentary. J Vasc Surg Venous Lymphat Disord. 2014 Jan; 2(1):60.
Benefit of anticoagulation for the treatment of lower extremity superficial venous thrombosis. J Vasc Surg Venous Lymphat Disord. 2015 Apr; 3(2):236-41.
Benefit of anticoagulation for the treatment of lower extremity superficial venous thrombosis.
Kabnick L, Wakefield T, Almeida J, Raffetto J, McLafferty R, Pappas P, Rectenwald J, Blebea J, Gillespie D, Onyeachom U, Kinsman R, Lal BK
Use of Compression Therapy in Patients with Chronic Venous Insufficiency Undergoing Ablation Therapy: A Report from the American Venous Registry. J Vasc Surg Venous Lymphat Disord. 2013 Jan; 1(1):107.
Use of Compression Therapy in Patients with Chronic Venous Insufficiency Undergoing Ablation Therapy: A Report from the American Venous Registry.
Lal BK, Almeida JI, Kabnick L, Wakefield TW, McLafferty RB, Pappas PJ, Raffetto JD, Raju S, Blebea J, Dalsing MC, Meissner M, Rectenwald J, Gillespie DL, Onyeachom U, Kinsman R
American Venous Registry - The First National Registry for the Treatment of Varicose Veins. J Vasc Surg Venous Lymphat Disord. 2013 Jan; 1(1):105.
American Venous Registry - The First National Registry for the Treatment of Varicose Veins.
Anwar MA, Vorkas P, Li J, Resslan O, Want E, Raffetto JD, Khalil RA, Holmes E, Davies AH
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Prolonged Mechanical Stretch Alters the Metabolic Profile in Rat Inferior Vena Cava.
Daniel VT, Gupta N, Raffetto JD, McPhee JT
Impact of coexisting aneurysms on open revascularization for aortoiliac occlusive disease. J Vasc Surg. 2016 Apr; 63(4):944-8.
Impact of coexisting aneurysms on open revascularization for aortoiliac occlusive disease.
Madenci AL, Ozaki CK, Gupta N, Raffetto JD, Belkin M, McPhee JT
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Perioperative outcomes of elective inflow revascularization for lower extremity claudication in the American College of Surgeons National Surgical Quality Improvement Program database.
Raffetto JD, Eberhardt RT, Dean SM, Ligi D, Mannello F
Pharmacologic treatment to improve venous leg ulcer healing. J Vasc Surg Venous Lymphat Disord. 2016 07; 4(3):371-4.
Pharmacologic treatment to improve venous leg ulcer healing.
McPhee JT, Madenci A, Raffetto J, Martin M, Gupta N
Contemporary comparison of aortofemoral bypass to alternative inflow procedures in the Veteran population. J Vasc Surg. 2016 Dec; 64(6):1660-1666.
Contemporary comparison of aortofemoral bypass to alternative inflow procedures in the Veteran population.
Ligi D, Mosti G, Croce L, Raffetto JD, Mannello F
Chronic venous disease - Part II: Proteolytic biomarkers in wound healing. Biochim Biophys Acta. 2016 10; 1862(10):1900-8.
Chronic venous disease - Part II: Proteolytic biomarkers in wound healing.
Soedjak H, Hajdu J, Raffetto JD, Cano R, Bales BL, Prasad LS, Kispert LD
The structure of streptonigrin semiquinone in solution. Biochim Biophys Acta. 1997 Apr 17; 1335(1-2):73-90.
The structure of streptonigrin semiquinone in solution.
Chronic venous disease - Part I: Inflammatory biomarkers in wound healing. Biochim Biophys Acta. 2016 10; 1862(10):1964-74.
Chronic venous disease - Part I: Inflammatory biomarkers in wound healing.
Anwar MA, Vorkas PA, Li J, Adesina-Georgiadis KN, Reslan OM, Raffetto JD, Want EJ, Khalil RA, Holmes E, Davies AH
Prolonged Mechanical Circumferential Stretch Induces Metabolic Changes in Rat Inferior Vena Cava. Eur J Vasc Endovasc Surg. 2016 Oct; 52(4):544-552.
Prolonged Mechanical Circumferential Stretch Induces Metabolic Changes in Rat Inferior Vena Cava.
Which dressings reduce inflammation and improve venous leg ulcer healing. Phlebology. 2014 May; 29(1 suppl):157-164.
Which dressings reduce inflammation and improve venous leg ulcer healing.
Aziz F, Raffetto JD, Diaz JA, Myers DD, Ozsvath KJ, Carman TL, Lal BK
Practice patterns of adjunctive therapy for venous leg ulcers. Phlebology. 2017 Feb; 32(1):19-26.
Practice patterns of adjunctive therapy for venous leg ulcers.
Reslan OM, Sundick S, Razayat C, Brener BJ, Raffetto JD
Rupture of a True Profunda Femoris Artery Aneurysm: Two Case Reports and Review of the English Language Literature. Ann Vasc Surg. 2017 Feb; 39:290.e1-290.e9.
Rupture of a True Profunda Femoris Artery Aneurysm: Two Case Reports and Review of the English Language Literature.
Labropoulos N, Summers KL, Sanchez IE, Raffetto J
Saphenous vein wall thickness in age and venous reflux-associated remodeling in adults. J Vasc Surg Venous Lymphat Disord. 2017 03; 5(2):216-223.
Saphenous vein wall thickness in age and venous reflux-associated remodeling in adults.
Raffetto JD, Leverkus M, Park HY, Menzoian JO
Synopsis on cellular senescence and apoptosis. J Vasc Surg. 2001 Jul; 34(1):173-7.
Synopsis on cellular senescence and apoptosis.
Invited commentary. J Vasc Surg. 2016 11; 64(5):1458.
Bush R, Comerota A, Meissner M, Raffetto JD, Hahn SR, Freeman K
Recommendations for the medical management of chronic venous disease: The role of Micronized Purified Flavanoid Fraction (MPFF). Phlebology. 2017 Apr; 32(1_suppl):3-19.
Recommendations for the medical management of chronic venous disease: The role of Micronized Purified Flavanoid Fraction (MPFF).
Raffetto JD, Montgomery JE, Eberhardt RT, LaMorte WW, Menzoian JO
Journal of the American College of Surgeons
Differences in risk factors for lower extremity arterial occlusive disease. J Am Coll Surg. 2005 Dec; 201(6):918-24.
Differences in risk factors for lower extremity arterial occlusive disease.
Huang AL, Silver AE, Shvenke E, Schopfer DW, Jahangir E, Titas MA, Shpilman A, Menzoian JO, Watkins MT, Raffetto JD, Gibbons G, Woodson J, Shaw PM, Dhadly M, Eberhardt RT, Keaney JF, Gokce N, Vita JA
Arteriosclerosis, thrombosis, and vascular biology
Predictive value of reactive hyperemia for cardiovascular events in patients with peripheral arterial disease undergoing vascular surgery. Arterioscler Thromb Vasc Biol. 2007 Oct; 27(10):2113-9.
Predictive value of reactive hyperemia for cardiovascular events in patients with peripheral arterial disease undergoing vascular surgery.
Images in clinical medicine. Giant abdominal aortic aneurysm. N Engl J Med. 2010 Jan 07; 362(1):66.
Images in clinical medicine. Giant abdominal aortic aneurysm.
Yu NR, Eberhardt RT, Menzoian JO, Urick CL, Raffetto JD
Vertebral artery dissection following intravascular catheter placement: a case report and review of the literature. Vasc Med. 2004 May; 9(3):199-203.
Vertebral artery dissection following intravascular catheter placement: a case report and review of the literature.
Marien BJ, Raffetto JD, Seidman CS, LaMorte WW, Menzoian JO
Archives of surgery (Chicago, Ill. : 1960)
Bovine pericardium vs dacron for patch angioplasty after carotid endarterectomy: a prospective randomized study. Arch Surg. 2002 Jul; 137(7):785-8.
Bovine pericardium vs dacron for patch angioplasty after carotid endarterectomy: a prospective randomized study.
Suliman AS, Raffetto JD, Seidman CS, Menzoian JO
Acute thrombosis of abdominal aortic aneurysms--report of two cases and review of the literature. Vasc Endovascular Surg. 2003 Jan-Feb; 37(1):71-5.
Acute thrombosis of abdominal aortic aneurysms--report of two cases and review of the literature.
Progress in molecular biology and translational science
Matrix Metalloproteinases in Remodeling of Lower Extremity Veins and Chronic Venous Disease. Prog Mol Biol Transl Sci. 2017; 147:267-299.
Matrix Metalloproteinases in Remodeling of Lower Extremity Veins and Chronic Venous Disease.
Vasquez R, Marien BJ, Gram C, Goodwin DG, Menzoian JO, Raffetto JD
Proliferative capacity of venous ulcer wound fibroblasts in the presence of platelet-derived growth factor. Vasc Endovascular Surg. 2004 Jul-Aug; 38(4):355-60.
Proliferative capacity of venous ulcer wound fibroblasts in the presence of platelet-derived growth factor.
Raffetto JD, Chen MN, LaMorte WW, Seidman CS, Eberhardt RT, Woodson J, Gibbons GW, Menzoian JO
Factors that predict site of outflow target artery anastomosis in infrainguinal revascularization. J Vasc Surg. 2002 Jun; 35(6):1093-9.
Factors that predict site of outflow target artery anastomosis in infrainguinal revascularization.
Matrix metalloproteinases in venous tissue remodeling and varicose vein formation. Curr Vasc Pharmacol. 2008 Jul; 6(3):158-72.
Matrix metalloproteinases in venous tissue remodeling and varicose vein formation.
Noninfectious saccular abdominal aortic aneurysm--a report of two cases. Vasc Endovascular Surg. 2003 Sep-Oct; 37(5):353-8.
Noninfectious saccular abdominal aortic aneurysm--a report of two cases.
Chronic venous insufficiency. Circulation. 2005 May 10; 111(18):2398-409.
Matrix metalloproteinase 2-induced venous dilation via hyperpolarization and activation of K+ channels: relevance to varicose vein formation. J Vasc Surg. 2007 Feb; 45(2):373-80.
Matrix metalloproteinase 2-induced venous dilation via hyperpolarization and activation of K+ channels: relevance to varicose vein formation.
Single-incision external iliac artery endarterectomy and patch angioplasty. Ann Vasc Surg. 2011 Nov; 25(8):1165-9.
Single-incision external iliac artery endarterectomy and patch angioplasty.
Bilateral asymptomatic extracranial carotid artery aneurysms. Ann Vasc Surg. 2010 Jul; 24(5):691.e11-6.
Bilateral asymptomatic extracranial carotid artery aneurysms.
Reply. J Vasc Surg Venous Lymphat Disord. 2017 09; 5(5):772.
American journal of translational research
Matrix metalloproteinase activity and glycosaminoglycans in chronic venous disease: the linkage among cell biology, pathology and translational research. Am J Transl Res. 2011 Feb; 3(2):149-58.
Matrix metalloproteinase activity and glycosaminoglycans in chronic venous disease: the linkage among cell biology, pathology and translational research.
Raffetto JD, Qiao X, Beauregard KG, Tanbe AF, Kumar A, Mam V, Khalil RA
Functional adaptation of venous smooth muscle response to vasoconstriction in proximal, distal, and varix segments of varicose veins. J Vasc Surg. 2010 Apr; 51(4):962-71.
Functional adaptation of venous smooth muscle response to vasoconstriction in proximal, distal, and varix segments of varicose veins.
Hirji SA, Robertson FC, Casillas S, McPhee JT, Gupta N, Martin MC, Raffetto JD
Asymptomatic portal vein aneurysms: To treat, or not to treat? Phlebology. 2018 Sep; 33(8):513-516.
Asymptomatic portal vein aneurysms: To treat, or not to treat?
Raffetto JD, Cheung Y, Fisher JB, Cantelmo NL, Watkins MT, Lamorte WW, Menzoian JO
Incision and abdominal wall hernias in patients with aneurysm or occlusive aortic disease. J Vasc Surg. 2003 Jun; 37(6):1150-4.
Incision and abdominal wall hernias in patients with aneurysm or occlusive aortic disease.
Ligi D, Croce L, Mosti G, Raffetto JD, Mannello F
International journal of molecular sciences
Chronic Venous Insufficiency: Transforming Growth Factor-ß Isoforms and Soluble Endoglin Concentration in Different States of Wound Healing. Int J Mol Sci. 2017 Oct 21; 18(10).
Chronic Venous Insufficiency: Transforming Growth Factor-ß Isoforms and Soluble Endoglin Concentration in Different States of Wound Healing.
Meissner MH, Gloviczki P, Comerota AJ, Dalsing MC, Eklof BG, Gillespie DL, Lohr JM, McLafferty RB, Murad MH, Padberg F, Pappas P, Raffetto JD, Wakefield TW
Early thrombus removal strategies for acute deep venous thrombosis: clinical practice guidelines of the Society for Vascular Surgery and the American Venous Forum. J Vasc Surg. 2012 May; 55(5):1449-62.
Early thrombus removal strategies for acute deep venous thrombosis: clinical practice guidelines of the Society for Vascular Surgery and the American Venous Forum.
Raffetto JD, Vasquez R, Goodwin DG, Menzoian JO
Mitogen-activated protein kinase pathway regulates cell proliferation in venous ulcer fibroblasts. Vasc Endovascular Surg. 2006 Jan-Feb; 40(1):59-66.
Mitogen-activated protein kinase pathway regulates cell proliferation in venous ulcer fibroblasts.
The definition of the venous ulcer. J Vasc Surg. 2010 Nov; 52(5 Suppl):46S-49S.
Chronic traumatic pseudoaneurysm of polytetrafluoroethylene axillofemoral bypass graft in a quadriplegic patient. Ann Vasc Surg. 2008 Sep; 22(5):688-91.
Chronic traumatic pseudoaneurysm of polytetrafluoroethylene axillofemoral bypass graft in a quadriplegic patient.
Owens CD, Kim JM, Hevelone ND, Hamdan A, Raffetto JD, Creager MA, Conte MS
Novel adipokines, high molecular weight adiponectin and resistin, are associated with outcomes following lower extremity revascularization with autogenous vein. J Vasc Surg. 2010 May; 51(5):1152-9.
Novel adipokines, high molecular weight adiponectin and resistin, are associated with outcomes following lower extremity revascularization with autogenous vein.
Gloviczki P, Comerota AJ, Dalsing MC, Eklof BG, Gillespie DL, Gloviczki ML, Lohr JM, McLafferty RB, Meissner MH, Murad MH, Padberg FT, Pappas PJ, Passman MA, Raffetto JD, Vasquez MA, Wakefield TW
The care of patients with varicose veins and associated chronic venous diseases: clinical practice guidelines of the Society for Vascular Surgery and the American Venous Forum. J Vasc Surg. 2011 May; 53(5 Suppl):2S-48S.
The care of patients with varicose veins and associated chronic venous diseases: clinical practice guidelines of the Society for Vascular Surgery and the American Venous Forum.
Raffetto JD, Qiao X, Koledova VV, Khalil RA
Prolonged increases in vein wall tension increase matrix metalloproteinases and decrease constriction in rat vena cava: Potential implications in varicose veins. J Vasc Surg. 2008 Aug; 48(2):447-56.
Prolonged increases in vein wall tension increase matrix metalloproteinases and decrease constriction in rat vena cava: Potential implications in varicose veins.
Raffetto JD, Gram CH, Overman KC, Menzoian JO
Mitogen-activated protein kinase p38 pathway in venous ulcer fibroblasts. Vasc Endovascular Surg. 2008 Aug-Sep; 42(4):367-74.
Mitogen-activated protein kinase p38 pathway in venous ulcer fibroblasts.
Reslan OM, Ebaugh JL, Gupta N, Brecher SM, Itani KM, Raffetto JD
Acute expansion of a hospital-acquired methicillin-resistant Staphylococcus aureus-infected abdominal aortic aneurysm. Ann Vasc Surg. 2012 Jul; 26(5):732.e1-6.
Acute expansion of a hospital-acquired methicillin-resistant Staphylococcus aureus-infected abdominal aortic aneurysm.
Raffetto JD, Qiao X, Beauregard KG, Khalil RA
Estrogen receptor-mediated enhancement of venous relaxation in female rat: implications in sex-related differences in varicose veins. J Vasc Surg. 2010 Apr; 51(4):972-81.
Estrogen receptor-mediated enhancement of venous relaxation in female rat: implications in sex-related differences in varicose veins.
Raffetto JD, Mendez MV, Phillips TJ, Park HY, Menzoian JO
The effect of passage number on fibroblast cellular senescence in patients with chronic venous insufficiency with and without ulcer. Am J Surg. 1999 Aug; 178(2):107-12.
The effect of passage number on fibroblast cellular senescence in patients with chronic venous insufficiency with and without ulcer.
Lemos DW, Raffetto JD, Moore TC, Menzoian JO
Primary aortoduodenal fistula: a case report and review of the literature. J Vasc Surg. 2003 Mar; 37(3):686-9.
Primary aortoduodenal fistula: a case report and review of the literature.
Aortobifemoral graft infection with Mycobacterium tuberculosis: treatment with abscess drainage, debridement, and long-term administration of antibiotic agents. J Vasc Surg. 2004 Oct; 40(4):826-9.
Aortobifemoral graft infection with Mycobacterium tuberculosis: treatment with abscess drainage, debridement, and long-term administration of antibiotic agents.
Volpe CM, Raffetto JD, Collure DW, Hoover EL, Doerr RJ
Unilateral male breast masses: cancer risk and their evaluation and management. Am Surg. 1999 Mar; 65(3):250-3.
Unilateral male breast masses: cancer risk and their evaluation and management.