Lange, Christoph
eCommons Login: CL41
first name: Christoph
last name: Lange
coauthor of: Hahn, Georg
coauthor of: Lutz, Sharon
coauthor of: Weiss, Scott
coauthor of: Prokopenko, Dmitry
coauthor of: Laird, Nan
full name: Christoph Lange, Ph.D.
has faculty rank: Full Professor
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photo: https://connects.catalyst.harvard.edu/Profiles/profile/Modules/CustomViewPersonGeneralInfo/PhotoHandler.ashx
Person ID: 22120
person in primary position: Professor of Biostatistics
physical neighbor: Coull, Brent
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similar to: Furin, Jennifer
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selected publications: Authorship 1812953
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Authorship 101364
type: Authorship
author rank in publication: 5
linked author: Lange, Christoph
linked information resource: Using canonical correlation analysis to discover genetic regulatory variants.

Most antiviral CD8 T cells during chronic viral infection do not express high levels of perforin and are not directly cytotoxic.
PubMed Identifier: 12393740
author list: Zhang D, Shankar P, Xu Z, Harnisch B, Chen G, Lange C, Lee SJ, Valdez H, Lederman MM, Lieberman J
published in: Blood
information resource reference: Most antiviral CD8 T cells during chronic viral infection do not express high levels of perforin and are not directly cytotoxic. Blood. 2003 Jan 01; 101(1):226-35.
journal title abbreviation: Blood
publication date: 2002-08-22T00:00:00
year: 2002
type: Academic Article
type: Article
type: Document
type: Information Resource

Family-based association tests for survival and times-to-onset analysis.
PubMed Identifier: 14716720
author list: Lange C, Blacker D, Laird NM
published in: Statistics in medicine
information resource reference: Family-based association tests for survival and times-to-onset analysis. Stat Med. 2004 Jan 30; 23(2):179-89.
journal title abbreviation: Stat Med
publication date: 2004-01-30T00:00:00
year: 2004
type: Academic Article
type: Article
type: Document
type: Information Resource

The IL12B gene is associated with asthma.
PubMed Identifier: 15322986
author list: Randolph AG, Lange C, Silverman EK, Lazarus R, Silverman ES, Raby B, Brown A, Ozonoff A, Richter B, Weiss ST
published in: American journal of human genetics
information resource reference: The IL12B gene is associated with asthma. Am J Hum Genet. 2004 Oct; 75(4):709-15.
journal title abbreviation: Am J Hum Genet
publication date: 2004-08-20T00:00:00
year: 2004
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1054213
type: Authorship
author rank in publication: 12
linked author: Lange, Christoph
linked information resource: Treatment outcome definitions in nontuberculous mycobacterial pulmonary disease: an NTM-NET consensus statement.

Treatment outcome definitions in nontuberculous mycobacterial pulmonary disease: an NTM-NET consensus statement.
PubMed Identifier: 29567726
author list: van Ingen J, Aksamit T, Andrejak C, Böttger EC, Cambau E, Daley CL, Griffith DE, Guglielmetti L, Holland SM, Huitt GA, Koh WJ, Lange C, Leitman P, Marras TK, Morimoto K, Olivier KN, Santin M, Stout JE, Thomson R, Tortoli E, Wallace RJ, Winthrop KL, Wagner D
published in: The European respiratory journal
information resource reference: Treatment outcome definitions in nontuberculous mycobacterial pulmonary disease: an NTM-NET consensus statement. Eur Respir J. 2018 03; 51(3).
journal title abbreviation: Eur Respir J
publication date: 2018-03-22T00:00:00
year: 2018
type: Academic Article
type: Article
type: Document
type: Information Resource

Family-based association test for time-to-onset data with time-dependent differences between the hazard functions.
PubMed Identifier: 16374805
author list: Jiang H, Harrington D, Raby BA, Bertram L, Blacker D, Weiss ST, Lange C
published in: Genetic epidemiology
information resource reference: Family-based association test for time-to-onset data with time-dependent differences between the hazard functions. Genet Epidemiol. 2006 Feb; 30(2):124-32.
journal title abbreviation: Genet Epidemiol
publication date: 2006-02-01T00:00:00
year: 2006
type: Academic Article
type: Article
type: Document
type: Information Resource

Genomic screening in family-based association testing.
PubMed Identifier: 16451572
author list: Murphy A, McQueen MB, Su J, Kraft P, Lazarus R, Laird NM, Lange C, Van Steen K
published in: BMC genetics
information resource reference: Genomic screening in family-based association testing. BMC Genet. 2005 Dec 30; 6 Suppl 1:S115.
journal title abbreviation: BMC Genet
publication date: 2005-12-30T00:00:00
year: 2005
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 105691
type: Authorship
author rank in publication: 35
linked author: Lange, Christoph
linked information resource: Genome-wide meta-analyses of nonsyndromic cleft lip with or without cleft palate identify six new risk loci.

Authorship 1055669
type: Authorship
author rank in publication: 1
linked author: Lange, Christoph
linked information resource: Time to revise WHO-recommended definitions of MDR-TB treatment outcomes.

Authorship 1054849
type: Authorship
author rank in publication: 3
linked author: Lange, Christoph
linked information resource: Pan-tuberculosis regimens: an argument against.

Time to revise WHO-recommended definitions of MDR-TB treatment outcomes.
PubMed Identifier: 29595505
author list: Lange C, van Leth F, Mitnick CD, Dheda K, Günther G
published in: The Lancet. Respiratory medicine
information resource reference: Time to revise WHO-recommended definitions of MDR-TB treatment outcomes. Lancet Respir Med. 2018 04; 6(4):246-248.
journal title abbreviation: Lancet Respir Med
publication date: 2018-04-01T00:00:00
year: 2018
type: Academic Article
type: Article
type: Document
type: Information Resource

Pan-tuberculosis regimens: an argument against.
PubMed Identifier: 29595502
author list: Dheda K, Gumbo T, Lange C, Horsburgh CR, Furin J
published in: The Lancet. Respiratory medicine
information resource reference: Pan-tuberculosis regimens: an argument against. Lancet Respir Med. 2018 04; 6(4):240-242.
journal title abbreviation: Lancet Respir Med
publication date: 2018-04-01T00:00:00
year: 2018
type: Academic Article
type: Article
type: Document
type: Information Resource

Evidence for an association of the dopamine D5 receptor gene on age at onset of attention deficit hyperactivity disorder.
PubMed Identifier: 17501935
author list: Lasky-Su J, Biederman J, Laird N, Tsuang M, Doyle AE, Smoller JW, Lange C, Faraone SV
published in: Annals of human genetics
information resource reference: Evidence for an association of the dopamine D5 receptor gene on age at onset of attention deficit hyperactivity disorder. Ann Hum Genet. 2007 Sep; 71(Pt 5):648-59.
journal title abbreviation: Ann Hum Genet
publication date: 2007-05-14T00:00:00
year: 2007
type: Academic Article
type: Article
type: Document
type: Information Resource

Mapping quantitative trait Loci using generalized estimating equations.
PubMed Identifier: 11729173
author list: Lange C, Whittaker JC
published in: Genetics
information resource reference: Mapping quantitative trait Loci using generalized estimating equations. Genetics. 2001 Nov; 159(3):1325-37.
journal title abbreviation: Genetics
publication date: 2001-11-01T00:00:00
year: 2001
type: Academic Article
type: Article
type: Document
type: Information Resource

On prediction of genetic values in marker-assisted selection.
PubMed Identifier: 11729177
author list: Lange C, Whittaker JC
published in: Genetics
information resource reference: On prediction of genetic values in marker-assisted selection. Genetics. 2001 Nov; 159(3):1375-81.
journal title abbreviation: Genetics
publication date: 2001-11-01T00:00:00
year: 2001
type: Academic Article
type: Article
type: Document
type: Information Resource

On genome-wide association studies for family-based designs: an integrative analysis approach combining ascertained family samples with unselected controls.
PubMed Identifier: 20346434
author list: Lasky-Su J, Won S, Mick E, Anney RJ, Franke B, Neale B, Biederman J, Smalley SL, Loo SK, Todorov A, Faraone SV, Weiss ST, Lange C
published in: American journal of human genetics
information resource reference: On genome-wide association studies for family-based designs: an integrative analysis approach combining ascertained family samples with unselected controls. Am J Hum Genet. 2010 Apr 09; 86(4):573-80.
journal title abbreviation: Am J Hum Genet
publication date: 2010-03-25T00:00:00
year: 2010
type: Academic Article
type: Article
type: Document
type: Information Resource

Genome-wide association analysis of body mass in chronic obstructive pulmonary disease.
PubMed Identifier: 21037115
author list: Wan ES, Cho MH, Boutaoui N, Klanderman BJ, Sylvia JS, Ziniti JP, Won S, Lange C, Pillai SG, Anderson WH, Kong X, Lomas DA, Bakke PS, Gulsvik A, Regan EA, Murphy JR, Make BJ, Crapo JD, Wouters EF, Celli BR, Silverman EK, DeMeo DL
published in: American journal of respiratory cell and molecular biology
information resource reference: Genome-wide association analysis of body mass in chronic obstructive pulmonary disease. Am J Respir Cell Mol Biol. 2011 Aug; 45(2):304-10.
journal title abbreviation: Am J Respir Cell Mol Biol
publication date: 2010-10-29T00:00:00
year: 2010
type: Academic Article
type: Article
type: Document
type: Information Resource

Assessment of Alzheimer's disease case-control associations using family-based methods.
PubMed Identifier: 18830724
author list: Schjeide BM, McQueen MB, Mullin K, DiVito J, Hogan MF, Parkinson M, Hooli B, Lange C, Blacker D, Tanzi RE, Bertram L
published in: Neurogenetics
information resource reference: Assessment of Alzheimer's disease case-control associations using family-based methods. Neurogenetics. 2009 Feb; 10(1):19-25.
journal title abbreviation: Neurogenetics
publication date: 2008-10-02T00:00:00
year: 2008
type: Academic Article
type: Article
type: Document
type: Information Resource

Genome-wide association scan of the time to onset of attention deficit hyperactivity disorder.
PubMed Identifier: 18937294
author list: Lasky-Su J, Anney RJ, Neale BM, Franke B, Zhou K, Maller JB, Vasquez AA, Chen W, Asherson P, Buitelaar J, Banaschewski T, Ebstein R, Gill M, Miranda A, Mulas F, Oades RD, Roeyers H, Rothenberger A, Sergeant J, Sonuga-Barke E, Steinhausen HC, Taylor E, Daly M, Laird N, Lange C, Faraone SV
published in: American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics
information resource reference: Genome-wide association scan of the time to onset of attention deficit hyperactivity disorder. Am J Med Genet B Neuropsychiatr Genet. 2008 Dec 05; 147B(8):1355-8.
journal title abbreviation: Am J Med Genet B Neuropsychiatr Genet
publication date: 2008-12-05T00:00:00
year: 2008
type: Academic Article
type: Article
type: Document
type: Information Resource

Recovering unused information in genome-wide association studies: the benefit of analyzing SNPs out of Hardy-Weinberg equilibrium.
PubMed Identifier: 19491930
author list: Fardo DW, Becker KD, Bertram L, Tanzi RE, Lange C
published in: European journal of human genetics : EJHG
information resource reference: Recovering unused information in genome-wide association studies: the benefit of analyzing SNPs out of Hardy-Weinberg equilibrium. Eur J Hum Genet. 2009 Dec; 17(12):1676-82.
journal title abbreviation: Eur J Hum Genet
publication date: 2009-06-03T00:00:00
year: 2009
type: Academic Article
type: Article
type: Document
type: Information Resource

Development of a Pharmacogenetic Predictive Test in asthma: proof of concept.
PubMed Identifier: 20032818
author list: Wu AC, Himes BE, Lasky-Su J, Litonjua A, Li L, Lange C, Lima J, Irvin CG, Weiss ST
published in: Pharmacogenetics and genomics
information resource reference: Development of a Pharmacogenetic Predictive Test in asthma: proof of concept. Pharmacogenet Genomics. 2010 Feb; 20(2):86-93.
journal title abbreviation: Pharmacogenet Genomics
publication date: 2010-02-01T00:00:00
year: 2010
type: Academic Article
type: Article
type: Document
type: Information Resource

Variants in FAM13A are associated with chronic obstructive pulmonary disease.
PubMed Identifier: 20173748
author list: Cho MH, Boutaoui N, Klanderman BJ, Sylvia JS, Ziniti JP, Hersh CP, DeMeo DL, Hunninghake GM, Litonjua AA, Sparrow D, Lange C, Won S, Murphy JR, Beaty TH, Regan EA, Make BJ, Hokanson JE, Crapo JD, Kong X, Anderson WH, Tal-Singer R, Lomas DA, Bakke P, Gulsvik A, Pillai SG, Silverman EK
published in: Nature genetics
information resource reference: Variants in FAM13A are associated with chronic obstructive pulmonary disease. Nat Genet. 2010 Mar; 42(3):200-2.
journal title abbreviation: Nat Genet
publication date: 2010-02-21T00:00:00
year: 2010
type: Academic Article
type: Article
type: Document
type: Information Resource

MMP12, lung function, and COPD in high-risk populations.
PubMed Identifier: 20018959
author list: Hunninghake GM, Cho MH, Tesfaigzi Y, Soto-Quiros ME, Avila L, Lasky-Su J, Stidley C, Melén E, Söderhäll C, Hallberg J, Kull I, Kere J, Svartengren M, Pershagen G, Wickman M, Lange C, Demeo DL, Hersh CP, Klanderman BJ, Raby BA, Sparrow D, Shapiro SD, Silverman EK, Litonjua AA, Weiss ST, Celedón JC
published in: The New England journal of medicine
information resource reference: MMP12, lung function, and COPD in high-risk populations. N Engl J Med. 2009 Dec 31; 361(27):2599-608.
journal title abbreviation: N Engl J Med
publication date: 2009-12-16T00:00:00
year: 2009
type: Academic Article
type: Article
type: Document
type: Information Resource

An omnibus test for family-based association studies with multiple SNPs and multiple phenotypes.
PubMed Identifier: 20087406
author list: Lasky-Su J, Murphy A, McQueen MB, Weiss S, Lange C
published in: European journal of human genetics : EJHG
information resource reference: An omnibus test for family-based association studies with multiple SNPs and multiple phenotypes. Eur J Hum Genet. 2010 Jun; 18(6):720-5.
journal title abbreviation: Eur J Hum Genet
publication date: 2010-01-20T00:00:00
year: 2010
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 104001
type: Authorship
author rank in publication: 2
linked author: Lange, Christoph
linked information resource: Quantitative trait prediction based on genetic marker-array data, a simulation study.

Comprehensive testing of positionally cloned asthma genes in two populations.
PubMed Identifier: 17702965
author list: Hersh CP, Raby BA, Soto-Quirós ME, Murphy AJ, Avila L, Lasky-Su J, Sylvia JS, Klanderman BJ, Lange C, Weiss ST, Celedón JC
published in: American journal of respiratory and critical care medicine
information resource reference: Comprehensive testing of positionally cloned asthma genes in two populations. Am J Respir Crit Care Med. 2007 Nov 01; 176(9):849-57.
journal title abbreviation: Am J Respir Crit Care Med
publication date: 2007-08-16T00:00:00
year: 2007
type: Academic Article
type: Article
type: Document
type: Information Resource

Estimating the number of unseen variants in the human genome.
PubMed Identifier: 19276111
author list: Ionita-Laza I, Lange C, M Laird N
published in: Proceedings of the National Academy of Sciences of the United States of America
information resource reference: Estimating the number of unseen variants in the human genome. Proc Natl Acad Sci U S A. 2009 Mar 31; 106(13):5008-13.
journal title abbreviation: Proc Natl Acad Sci U S A
publication date: 2009-03-10T00:00:00
year: 2009
type: Academic Article
type: Article
type: Document
type: Information Resource

https://connects.catalyst.harvard.edu/Profiles/profile/1041185
PubMed Identifier: 19629167
author list: Fardo DW, Ionita-Laza I, Lange C
published in: PLoS genetics
information resource reference: On quality control measures in genome-wide association studies: a test to assess the genotyping quality of individual probands in family-based association studies and an application to the HapMap data. PLoS Genet. 2009 Jul; 5(7):e1000572.
journal title abbreviation: PLoS Genet
publication date: 2009-07-24T00:00:00
year: 2009
type: Academic Article
type: Article
type: Document
type: Information Resource
label: On quality control measures in genome-wide association studies: a test to assess the genotyping quality of individual probands in family-based association studies and an application to the HapMap data.

On the analysis of genome-wide association studies in family-based designs: a universal, robust analysis approach and an application to four genome-wide association studies.
PubMed Identifier: 19956679
author list: Won S, Wilk JB, Mathias RA, O'Donnell CJ, Silverman EK, Barnes K, O'Connor GT, Weiss ST, Lange C
published in: PLoS genetics
information resource reference: On the analysis of genome-wide association studies in family-based designs: a universal, robust analysis approach and an application to four genome-wide association studies. PLoS Genet. 2009 Nov; 5(11):e1000741.
journal title abbreviation: PLoS Genet
publication date: 2009-11-26T00:00:00
year: 2009
type: Academic Article
type: Article
type: Document
type: Information Resource

A genome-wide association study of COPD identifies a susceptibility locus on chromosome 19q13.
PubMed Identifier: 22080838
author list: Cho MH, Castaldi PJ, Wan ES, Siedlinski M, Hersh CP, Demeo DL, Himes BE, Sylvia JS, Klanderman BJ, Ziniti JP, Lange C, Litonjua AA, Sparrow D, Regan EA, Make BJ, Hokanson JE, Murray T, Hetmanski JB, Pillai SG, Kong X, Anderson WH, Tal-Singer R, Lomas DA, Coxson HO, Edwards LD, MacNee W, Vestbo J, Yates JC, Agusti A, Calverley PM, Celli B, Crim C, Rennard S, Wouters E, Bakke P, Gulsvik A, Crapo JD, Beaty TH, Silverman EK
published in: Human molecular genetics
information resource reference: A genome-wide association study of COPD identifies a susceptibility locus on chromosome 19q13. Hum Mol Genet. 2012 Feb 15; 21(4):947-57.
journal title abbreviation: Hum Mol Genet
publication date: 2011-11-11T00:00:00
year: 2011
type: Academic Article
type: Article
type: Document
type: Information Resource

Association between copy number variants in 16p11.2 and major depressive disorder in a German case-control sample.
PubMed Identifier: 22344817
author list: Degenhardt F, Priebe L, Herms S, Mattheisen M, Mühleisen TW, Meier S, Moebus S, Strohmaier J, Groß M, Breuer R, Lange C, Hoffmann P, Meyer-Lindenberg A, Heinz A, Walter H, Lucae S, Wolf C, Müller-Myhsok B, Holsboer F, Maier W, Rietschel M, Nöthen MM, Cichon S
published in: American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics
information resource reference: Association between copy number variants in 16p11.2 and major depressive disorder in a German case-control sample. Am J Med Genet B Neuropsychiatr Genet. 2012 Apr; 159B(3):263-73.
journal title abbreviation: Am J Med Genet B Neuropsychiatr Genet
publication date: 2012-02-17T00:00:00
year: 2012
type: Academic Article
type: Article
type: Document
type: Information Resource

Handling the data management needs of high-throughput sequencing data: SpeedGene, a compression algorithm for the efficient storage of genetic data.
PubMed Identifier: 22591016
author list: Qiao D, Yip WK, Lange C
published in: BMC bioinformatics
information resource reference: Handling the data management needs of high-throughput sequencing data: SpeedGene, a compression algorithm for the efficient storage of genetic data. BMC Bioinformatics. 2012 May 16; 13:100.
journal title abbreviation: BMC Bioinformatics
publication date: 2012-05-16T00:00:00
year: 2012
type: Academic Article
type: Article
type: Document
type: Information Resource

Increased expression of beta-defensin 1 (DEFB1) in chronic obstructive pulmonary disease.
PubMed Identifier: 21818276
author list: Andresen E, Günther G, Bullwinkel J, Lange C, Heine H
published in: PloS one
information resource reference: Increased expression of beta-defensin 1 (DEFB1) in chronic obstructive pulmonary disease. PLoS One. 2011; 6(7):e21898.
journal title abbreviation: PLoS One
publication date: 2011-07-19T00:00:00
year: 2011
type: Academic Article
type: Article
type: Document
type: Information Resource

Family-based association analysis of beta2-adrenergic receptor polymorphisms in the childhood asthma management program.
PubMed Identifier: 14610472
author list: Silverman EK, Kwiatkowski DJ, Sylvia JS, Lazarus R, Drazen JM, Lange C, Laird NM, Weiss ST
published in: The Journal of allergy and clinical immunology
information resource reference: Family-based association analysis of beta2-adrenergic receptor polymorphisms in the childhood asthma management program. J Allergy Clin Immunol. 2003 Nov; 112(5):870-6.
journal title abbreviation: J Allergy Clin Immunol
publication date: 2003-11-01T00:00:00
year: 2003
type: Academic Article
type: Article
type: Document
type: Information Resource

A family-based association test for repeatedly measured quantitative traits adjusting for unknown environmental and/or polygenic effects.
PubMed Identifier: 16646795
author list: Lange C, van Steen K, Andrew T, Lyon H, DeMeo DL, Raby B, Murphy A, Silverman EK, MacGregor A, Weiss ST, Laird NM
published in: Statistical applications in genetics and molecular biology
information resource reference: A family-based association test for repeatedly measured quantitative traits adjusting for unknown environmental and/or polygenic effects. Stat Appl Genet Mol Biol. 2004; 3:Article17.
journal title abbreviation: Stat Appl Genet Mol Biol
publication date: 2004-08-12T00:00:00
year: 2004
type: Academic Article
type: Article
type: Document
type: Information Resource

Whole-Genome Sequencing in Severe Chronic Obstructive Pulmonary Disease.
PubMed Identifier: 29949718
author list: Prokopenko D, Sakornsakolpat P, Fier HL, Qiao D, Parker MM, McDonald MN, Manichaikul A, Rich SS, Barr RG, Williams CJ, Brantly ML, Lange C, Beaty TH, Crapo JD, Silverman EK, Cho MH
published in: American journal of respiratory cell and molecular biology
information resource reference: Whole-Genome Sequencing in Severe Chronic Obstructive Pulmonary Disease. Am J Respir Cell Mol Biol. 2018 11; 59(5):614-622.
journal title abbreviation: Am J Respir Cell Mol Biol
publication date: 2018-11-01T00:00:00
year: 2018
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1076910
type: Authorship
author rank in publication: 12
linked author: Lange, Christoph
linked information resource: Whole-Genome Sequencing in Severe Chronic Obstructive Pulmonary Disease.

Is it rare or common?
PubMed Identifier: 22549767
author list: Adhikari K, AlChawa T, Ludwig K, Mangold E, Laird N, Lange C
published in: Genetic epidemiology
information resource reference: Is it rare or common? Genet Epidemiol. 2012 Jul; 36(5):419-29.
journal title abbreviation: Genet Epidemiol
publication date: 2012-04-30T00:00:00
year: 2012
type: Academic Article
type: Article
type: Document
type: Information Resource

IL10 gene polymorphisms are associated with asthma phenotypes in children.
PubMed Identifier: 14748015
author list: Lyon H, Lange C, Lake S, Silverman EK, Randolph AG, Kwiatkowski D, Raby BA, Lazarus R, Weiland KM, Laird N, Weiss ST
published in: Genetic epidemiology
information resource reference: IL10 gene polymorphisms are associated with asthma phenotypes in children. Genet Epidemiol. 2004 Feb; 26(2):155-65.
journal title abbreviation: Genet Epidemiol
publication date: 2004-02-01T00:00:00
year: 2004
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 107295
type: Authorship
author rank in publication: 2
linked author: Lange, Christoph
linked information resource: IL10 gene polymorphisms are associated with asthma phenotypes in children.

Authorship 112818
type: Authorship
author rank in publication: 3
linked author: Lange, Christoph
linked information resource: Attempted replication of reported chronic obstructive pulmonary disease candidate gene associations.

Family-based methods for linkage and association analysis.
PubMed Identifier: 18358323
author list: Laird NM, Lange C
published in: Advances in genetics
information resource reference: Family-based methods for linkage and association analysis. Adv Genet. 2008; 60:219-52.
journal title abbreviation: Adv Genet
publication date: 2008-01-01T00:00:00
year: 2008
type: Academic Article
type: Article
type: Document
type: Information Resource

Genetic association analysis of copy-number variation (CNV) in human disease pathogenesis.
PubMed Identifier: 18822366
author list: Ionita-Laza I, Rogers AJ, Lange C, Raby BA, Lee C
published in: Genomics
information resource reference: Genetic association analysis of copy-number variation (CNV) in human disease pathogenesis. Genomics. 2009 Jan; 93(1):22-6.
journal title abbreviation: Genomics
publication date: 2008-10-19T00:00:00
year: 2008
type: Academic Article
type: Article
type: Document
type: Information Resource

Genome-wide association analysis identifies PDE4D as an asthma-susceptibility gene.
PubMed Identifier: 19426955
author list: Himes BE, Hunninghake GM, Baurley JW, Rafaels NM, Sleiman P, Strachan DP, Wilk JB, Willis-Owen SA, Klanderman B, Lasky-Su J, Lazarus R, Murphy AJ, Soto-Quiros ME, Avila L, Beaty T, Mathias RA, Ruczinski I, Barnes KC, Celedón JC, Cookson WO, Gauderman WJ, Gilliland FD, Hakonarson H, Lange C, Moffatt MF, O'Connor GT, Raby BA, Silverman EK, Weiss ST
published in: American journal of human genetics
information resource reference: Genome-wide association analysis identifies PDE4D as an asthma-susceptibility gene. Am J Hum Genet. 2009 May; 84(5):581-93.
journal title abbreviation: Am J Hum Genet
publication date: 2009-05-07T00:00:00
year: 2009
type: Academic Article
type: Article
type: Document
type: Information Resource

HIV-1 infection impairs the bronchoalveolar T-cell response to mycobacteria.
PubMed Identifier: 19797156
author list: Kalsdorf B, Scriba TJ, Wood K, Day CL, Dheda K, Dawson R, Hanekom WA, Lange C, Wilkinson RJ
published in: American journal of respiratory and critical care medicine
information resource reference: HIV-1 infection impairs the bronchoalveolar T-cell response to mycobacteria. Am J Respir Crit Care Med. 2009 Dec 15; 180(12):1262-70.
journal title abbreviation: Am J Respir Crit Care Med
publication date: 2009-09-24T00:00:00
year: 2009
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1079761
type: Authorship
author rank in publication: 1
linked author: Lange, Christoph
linked information resource: AT2R (Angiotensin AT2 Receptor) Agonist, Compound 21, Prevents Abdominal Aortic Aneurysm Progression in the Rat.

AT2R (Angiotensin AT2 Receptor) Agonist, Compound 21, Prevents Abdominal Aortic Aneurysm Progression in the Rat.
PubMed Identifier: 29987108
author list: Lange C, Sommerfeld M, Namsolleck P, Kintscher U, Unger T, Kaschina E
published in: Hypertension (Dallas, Tex. : 1979)
information resource reference: AT2R (Angiotensin AT2 Receptor) Agonist, Compound 21, Prevents Abdominal Aortic Aneurysm Progression in the Rat. Hypertension. 2018 09; 72(3):e20-e29.
journal title abbreviation: Hypertension
publication date: 2018-09-01T00:00:00
year: 2018
type: Academic Article
type: Article
type: Document
type: Information Resource

Combining disease models to test for gene-environment interaction in nuclear families.
PubMed Identifier: 21401569
author list: Hoffmann TJ, Vansteelandt S, Lange C, Silverman EK, DeMeo DL, Laird NM
published in: Biometrics
information resource reference: Combining disease models to test for gene-environment interaction in nuclear families. Biometrics. 2011 Dec; 67(4):1260-70.
journal title abbreviation: Biometrics
publication date: 2011-03-14T00:00:00
year: 2011
type: Academic Article
type: Article
type: Document
type: Information Resource

Association of SERPINE2 with asthma.
PubMed Identifier: 21436250
author list: Himes BE, Klanderman B, Ziniti J, Senter-Sylvia J, Soto-Quiros ME, Avila L, Celedón JC, Lange C, Mariani TJ, Lasky-Su J, Hersh CP, Raby BA, Silverman EK, Weiss ST, DeMeo DL
published in: Chest
information resource reference: Association of SERPINE2 with asthma. Chest. 2011 Sep; 140(3):667-674.
journal title abbreviation: Chest
publication date: 2011-03-24T00:00:00
year: 2011
type: Academic Article
type: Article
type: Document
type: Information Resource

On the parsing of statistical information in family-based association testing.
PubMed Identifier: 17325672
author list: McQueen MB, Weiss S, Laird NM, Lange C
published in: Nature genetics
information resource reference: On the parsing of statistical information in family-based association testing. Nat Genet. 2007 Mar; 39(3):281-2.
journal title abbreviation: Nat Genet
publication date: 2007-03-01T00:00:00
year: 2007
type: Academic Article
type: Article
type: Document
type: Information Resource

Family-based association analysis of a statistically derived quantitative traits for ADHD reveal an association in DRD4 with inattentive symptoms in ADHD individuals.
PubMed Identifier: 17579349
author list: Lasky-Su J, Lange C, Biederman J, Tsuang M, Doyle AE, Smoller JW, Laird N, Faraone S
published in: American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics
information resource reference: Family-based association analysis of a statistically derived quantitative traits for ADHD reveal an association in DRD4 with inattentive symptoms in ADHD individuals. Am J Med Genet B Neuropsychiatr Genet. 2008 Jan 05; 147B(1):100-6.
journal title abbreviation: Am J Med Genet B Neuropsychiatr Genet
publication date: 2008-01-05T00:00:00
year: 2008
type: Academic Article
type: Article
type: Document
type: Information Resource

Genome-wide association scan of quantitative traits for attention deficit hyperactivity disorder identifies novel associations and confirms candidate gene associations.
PubMed Identifier: 18821565
author list: Lasky-Su J, Neale BM, Franke B, Anney RJ, Zhou K, Maller JB, Vasquez AA, Chen W, Asherson P, Buitelaar J, Banaschewski T, Ebstein R, Gill M, Miranda A, Mulas F, Oades RD, Roeyers H, Rothenberger A, Sergeant J, Sonuga-Barke E, Steinhausen HC, Taylor E, Daly M, Laird N, Lange C, Faraone SV
published in: American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics
information resource reference: Genome-wide association scan of quantitative traits for attention deficit hyperactivity disorder identifies novel associations and confirms candidate gene associations. Am J Med Genet B Neuropsychiatr Genet. 2008 Dec 05; 147B(8):1345-54.
journal title abbreviation: Am J Med Genet B Neuropsychiatr Genet
publication date: 2008-12-05T00:00:00
year: 2008
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1083800
type: Authorship
author rank in publication: 9
linked author: Lange, Christoph
linked information resource: An Unexpected Endobronchial Mass Appearing During Bronchoscopy.

An Unexpected Endobronchial Mass Appearing During Bronchoscopy.
PubMed Identifier: 30044749
author list: Salzer HJF, Kuempers C, Pasternack H, Heyckendorf J, Bialek R, Palade E, Hundack L, Kalsdorf B, Lange C
published in: Chest
information resource reference: An Unexpected Endobronchial Mass Appearing During Bronchoscopy. Chest. 2018 07; 154(1):e13-e21.
journal title abbreviation: Chest
publication date: 2018-07-01T00:00:00
year: 2018
type: Academic Article
type: Article
type: Document
type: Information Resource

Whole exome sequencing analysis in severe chronic obstructive pulmonary disease.
PubMed Identifier: 30060175
author list: Qiao D, Ameli A, Prokopenko D, Chen H, Kho AT, Parker MM, Morrow J, Hobbs BD, Liu Y, Beaty TH, Crapo JD, Barnes KC, Nickerson DA, Bamshad M, Hersh CP, Lomas DA, Agusti A, Make BJ, Calverley PMA, Donner CF, Wouters EF, Vestbo J, Paré PD, Levy RD, Rennard SI, Tal-Singer R, Spitz MR, Sharma A, Ruczinski I, Lange C, Silverman EK, Cho MH
published in: Human molecular genetics
information resource reference: Whole exome sequencing analysis in severe chronic obstructive pulmonary disease. Hum Mol Genet. 2018 11 01; 27(21):3801-3812.
journal title abbreviation: Hum Mol Genet
publication date: 2018-11-01T00:00:00
year: 2018
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1086144
type: Authorship
author rank in publication: 30
linked author: Lange, Christoph
linked information resource: Whole exome sequencing analysis in severe chronic obstructive pulmonary disease.

Authorship 1085823
type: Authorship
author rank in publication: 29
linked author: Lange, Christoph
linked information resource: Clinical Management of Multidrug-Resistant Tuberculosis in 16 European Countries.

Clinical Management of Multidrug-Resistant Tuberculosis in 16 European Countries.
PubMed Identifier: 29509468
author list: Günther G, van Leth F, Alexandru S, Altet N, Avsar K, Bang D, Barbuta R, Bothamley G, Ciobanu A, Crudu V, Danilovits M, Dedicoat M, Duarte R, Gualano G, Kunst H, de Lange W, Leimane V, McLaughlin AM, Magis-Escurra C, Muylle I, Polcová V, Popa C, Rumetshofer R, Skrahina A, Solodovnikova V, Spinu V, Tiberi S, Viiklepp P, Lange C
published in: American journal of respiratory and critical care medicine
information resource reference: Clinical Management of Multidrug-Resistant Tuberculosis in 16 European Countries. Am J Respir Crit Care Med. 2018 08 01; 198(3):379-386.
journal title abbreviation: Am J Respir Crit Care Med
publication date: 2018-08-01T00:00:00
year: 2018
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1086980
type: Authorship
author rank in publication: 15
linked author: Lange, Christoph
linked information resource: Epidemiological aspects of travel-related systemic endemic mycoses: a GeoSentinel analysis, 1997-2017.

Epidemiological aspects of travel-related systemic endemic mycoses: a GeoSentinel analysis, 1997-2017.
PubMed Identifier: 30085265
author list: Salzer HJF, Stoney RJ, Angelo KM, Rolling T, Grobusch MP, Libman M, López-Vélez R, Duvignaud A, Ásgeirsson H, Crespillo-Andújar C, Schwartz E, Gautret P, Bottieau E, Jordan S, Lange C, Hamer DH
published in: Journal of travel medicine
information resource reference: Epidemiological aspects of travel-related systemic endemic mycoses: a GeoSentinel analysis, 1997-2017. J Travel Med. 2018 08 01; 25(1).
journal title abbreviation: J Travel Med
publication date: 2018-08-01T00:00:00
year: 2018
type: Academic Article
type: Article
type: Document
type: Information Resource

On the adjustment for covariates in genetic association analysis: a novel, simple principle to infer direct causal effects.
PubMed Identifier: 19219893
author list: Vansteelandt S, Goetgeluk S, Lutz S, Waldman I, Lyon H, Schadt EE, Weiss ST, Lange C
published in: Genetic epidemiology
information resource reference: On the adjustment for covariates in genetic association analysis: a novel, simple principle to infer direct causal effects. Genet Epidemiol. 2009 Jul; 33(5):394-405.
journal title abbreviation: Genet Epidemiol
publication date: 2009-07-01T00:00:00
year: 2009
type: Academic Article
type: Article
type: Document
type: Information Resource

A Bayesian approach to genetic association studies with family-based designs.
PubMed Identifier: 20818722
author list: Naylor MG, Weiss ST, Lange C
published in: Genetic epidemiology
information resource reference: A Bayesian approach to genetic association studies with family-based designs. Genet Epidemiol. 2010 Sep; 34(6):569-74.
journal title abbreviation: Genet Epidemiol
publication date: 2010-09-01T00:00:00
year: 2010
type: Academic Article
type: Article
type: Document
type: Information Resource

Two-stage testing strategies for genome-wide association studies in family-based designs.
PubMed Identifier: 20652517
author list: Murphy A, T Weiss S, Lange C
published in: Methods in molecular biology (Clifton, N.J.)
information resource reference: Two-stage testing strategies for genome-wide association studies in family-based designs. Methods Mol Biol. 2010; 620:485-96.
journal title abbreviation: Methods Mol Biol
publication date: 2010-01-01T00:00:00
year: 2010
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1093540
type: Authorship
author rank in publication: 56
linked author: Lange, Christoph
linked information resource: Treatment correlates of successful outcomes in pulmonary multidrug-resistant tuberculosis: an individual patient data meta-analysis.

Treatment correlates of successful outcomes in pulmonary multidrug-resistant tuberculosis: an individual patient data meta-analysis.
PubMed Identifier: 30215381
author list: Ahmad N, Ahuja SD, Akkerman OW, Alffenaar JC, Anderson LF, Baghaei P, Bang D, Barry PM, Bastos ML, Behera D, Benedetti A, Bisson GP, Boeree MJ, Bonnet M, Brode SK, Brust JCM, Cai Y, Caumes E, Cegielski JP, Centis R, Chan PC, Chan ED, Chang KC, Charles M, Cirule A, Dalcolmo MP, D'Ambrosio L, de Vries G, Dheda K, Esmail A, Flood J, Fox GJ, Fréchet-Jachym M, Fregona G, Gayoso R, Gegia M, Gler MT, Gu S, Guglielmetti L, Holtz TH, Hughes J, Isaakidis P, Jarlsberg L, Kempker RR, Keshavjee S, Khan FA, Kipiani M, Koenig SP, Koh WJ, Kritski A, Kuksa L, Kvasnovsky CL, Kwak N, Lan Z, Lange C, Laniado-Laborín R, Lee M, Leimane V, Leung CC, Leung EC, Li PZ, Lowenthal P, Maciel EL, Marks SM, Mase S, Mbuagbaw L, Migliori GB, Milanov V, Miller AC, Mitnick CD, Modongo C, Mohr E, Monedero I, Nahid P, Ndjeka N, O'Donnell MR, Padayatchi N, Palmero D, Pape JW, Podewils LJ, Reynolds I, Riekstina V, Robert J, Rodriguez M, Seaworth B, Seung KJ, Schnippel K, Shim TS, Singla R, Smith SE, Sotgiu G, Sukhbaatar G, Tabarsi P, Tiberi S, Trajman A, Trieu L, Udwadia ZF, van der Werf TS, Veziris N, Viiklepp P, Vilbrun SC, Walsh K, Westenhouse J, Yew WW, Yim JJ, Zetola NM, Zignol M, Menzies D
published in: Lancet (London, England)
information resource reference: Treatment correlates of successful outcomes in pulmonary multidrug-resistant tuberculosis: an individual patient data meta-analysis. Lancet. 2018 09 08; 392(10150):821-834.
journal title abbreviation: Lancet
publication date: 2018-09-08T00:00:00
year: 2018
type: Academic Article
type: Article
type: Document
type: Information Resource

Dissecting direct and indirect genetic effects on chronic obstructive pulmonary disease (COPD) susceptibility.
PubMed Identifier: 23299987
author list: Siedlinski M, Tingley D, Lipman PJ, Cho MH, Litonjua AA, Sparrow D, Bakke P, Gulsvik A, Lomas DA, Anderson W, Kong X, Rennard SI, Beaty TH, Hokanson JE, Crapo JD, Lange C, Silverman EK
published in: Human genetics
information resource reference: Dissecting direct and indirect genetic effects on chronic obstructive pulmonary disease (COPD) susceptibility. Hum Genet. 2013 Apr; 132(4):431-41.
journal title abbreviation: Hum Genet
publication date: 2013-01-09T00:00:00
year: 2013
type: Academic Article
type: Article
type: Document
type: Information Resource

Family-based designs in the age of large-scale gene-association studies.
PubMed Identifier: 16619052
author list: Laird NM, Lange C
published in: Nature reviews. Genetics
information resource reference: Family-based designs in the age of large-scale gene-association studies. Nat Rev Genet. 2006 May; 7(5):385-94.
journal title abbreviation: Nat Rev Genet
publication date: 2006-05-01T00:00:00
year: 2006
type: Academic Article
type: Article
type: Document
type: Information Resource

P2BAT: a massive parallel implementation of PBAT for genome-wide association studies in R.
PubMed Identifier: 17021156
author list: Hoffmann T, Lange C
published in: Bioinformatics (Oxford, England)
information resource reference: P2BAT: a massive parallel implementation of PBAT for genome-wide association studies in R. Bioinformatics. 2006 Dec 15; 22(24):3103-5.
journal title abbreviation: Bioinformatics
publication date: 2006-10-04T00:00:00
year: 2006
type: Academic Article
type: Article
type: Document
type: Information Resource

Impact of population stratification on family-based association tests with longitudinal measurements.
PubMed Identifier: 19222384
author list: Ding X, Weiss S, Raby B, Lange C, Laird NM
published in: Statistical applications in genetics and molecular biology
information resource reference: Impact of population stratification on family-based association tests with longitudinal measurements. Stat Appl Genet Mol Biol. 2009; 8:Article 17.
journal title abbreviation: Stat Appl Genet Mol Biol
publication date: 2009-02-12T00:00:00
year: 2009
type: Academic Article
type: Article
type: Document
type: Information Resource

Differentiating population stratification from genotyping error using family data.
PubMed Identifier: 22111716
author list: Sebro R, Lange C, Laird NM, Rogus JJ, Risch NJ
published in: Annals of human genetics
information resource reference: Differentiating population stratification from genotyping error using family data. Ann Hum Genet. 2012 Jan; 76(1):42-52.
journal title abbreviation: Ann Hum Genet
publication date: 2011-11-23T00:00:00
year: 2011
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1115050
type: Authorship
author rank in publication: 1
linked author: Lange, Christoph
linked information resource: Revising the definition of extensively drug-resistant tuberculosis.

Revising the definition of extensively drug-resistant tuberculosis.
PubMed Identifier: 30420247
author list: Lange C, Chesov D, Furin J, Udwadia Z, Dheda K
published in: The Lancet. Respiratory medicine
information resource reference: Revising the definition of extensively drug-resistant tuberculosis. Lancet Respir Med. 2018 12; 6(12):893-895.
journal title abbreviation: Lancet Respir Med
publication date: 2018-11-09T00:00:00
year: 2018
type: Academic Article
type: Article
type: Document
type: Information Resource

TOLL-like receptor 10 genetic variation is associated with asthma in two independent samples.
PubMed Identifier: 15201134
author list: Lazarus R, Raby BA, Lange C, Silverman EK, Kwiatkowski DJ, Vercelli D, Klimecki WJ, Martinez FD, Weiss ST
published in: American journal of respiratory and critical care medicine
information resource reference: TOLL-like receptor 10 genetic variation is associated with asthma in two independent samples. Am J Respir Crit Care Med. 2004 Sep 15; 170(6):594-600.
journal title abbreviation: Am J Respir Crit Care Med
publication date: 2004-06-16T00:00:00
year: 2004
type: Academic Article
type: Article
type: Document
type: Information Resource

Attempted replication of reported chronic obstructive pulmonary disease candidate gene associations.
PubMed Identifier: 15817713
author list: Hersh CP, Demeo DL, Lange C, Litonjua AA, Reilly JJ, Kwiatkowski D, Laird N, Sylvia JS, Sparrow D, Speizer FE, Weiss ST, Silverman EK
published in: American journal of respiratory cell and molecular biology
information resource reference: Attempted replication of reported chronic obstructive pulmonary disease candidate gene associations. Am J Respir Cell Mol Biol. 2005 Jul; 33(1):71-8.
journal title abbreviation: Am J Respir Cell Mol Biol
publication date: 2005-04-07T00:00:00
year: 2005
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1116559
type: Authorship
author rank in publication: 1
linked author: Lange, Christoph
linked information resource: Clofazimine for the treatment of multidrug-resistant tuberculosis.

Clofazimine for the treatment of multidrug-resistant tuberculosis.
PubMed Identifier: 30472423
author list: Lange C, Chesov D, Heyckendorf J
published in: Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases
information resource reference: Clofazimine for the treatment of multidrug-resistant tuberculosis. Clin Microbiol Infect. 2019 02; 25(2):128-130.
journal title abbreviation: Clin Microbiol Infect
publication date: 2018-11-22T00:00:00
year: 2018
type: Academic Article
type: Article
type: Document
type: Information Resource

Genetic model testing and statistical power in population-based association studies of quantitative traits.
PubMed Identifier: 17352422
author list: Lettre G, Lange C, Hirschhorn JN
published in: Genetic epidemiology
information resource reference: Genetic model testing and statistical power in population-based association studies of quantitative traits. Genet Epidemiol. 2007 May; 31(4):358-62.
journal title abbreviation: Genet Epidemiol
publication date: 2007-05-01T00:00:00
year: 2007
type: Academic Article
type: Article
type: Document
type: Information Resource

ARG1 is a novel bronchodilator response gene: screening and replication in four asthma cohorts.
PubMed Identifier: 18617639
author list: Litonjua AA, Lasky-Su J, Schneiter K, Tantisira KG, Lazarus R, Klanderman B, Lima JJ, Irvin CG, Peters SP, Hanrahan JP, Liggett SB, Hawkins GA, Meyers DA, Bleecker ER, Lange C, Weiss ST
published in: American journal of respiratory and critical care medicine
information resource reference: ARG1 is a novel bronchodilator response gene: screening and replication in four asthma cohorts. Am J Respir Crit Care Med. 2008 Oct 01; 178(7):688-94.
journal title abbreviation: Am J Respir Crit Care Med
publication date: 2008-07-10T00:00:00
year: 2008
type: Academic Article
type: Article
type: Document
type: Information Resource

Genome-wide association studies of family data in pharmacogenetics: a case study.
PubMed Identifier: 19925427
author list: Murphy A, Lasky-Su J, Tantisira KG, Litonjua AA, Lange C, Weiss ST
published in: Current pharmaceutical design
information resource reference: Genome-wide association studies of family data in pharmacogenetics: a case study. Curr Pharm Des. 2009; 15(32):3764-72.
journal title abbreviation: Curr Pharm Des
publication date: 2009-01-01T00:00:00
year: 2009
type: Academic Article
type: Article
type: Document
type: Information Resource

S100A7/psoriasin expression in the human lung: unchanged in patients with COPD, but upregulated upon positive S. aureus detection.
PubMed Identifier: 21324122
author list: Andresen E, Lange C, Strodthoff D, Goldmann T, Fischer N, Sahly H, Branscheid D, Heine H
published in: BMC pulmonary medicine
information resource reference: S100A7/psoriasin expression in the human lung: unchanged in patients with COPD, but upregulated upon positive S. aureus detection. BMC Pulm Med. 2011 Feb 15; 11:10.
journal title abbreviation: BMC Pulm Med
publication date: 2011-02-15T00:00:00
year: 2011
type: Academic Article
type: Article
type: Document
type: Information Resource

On the meta-analysis of genome-wide association studies: a robust and efficient approach to combine population and family-based studies.
PubMed Identifier: 22261799
author list: Won S, Lu Q, Bertram L, Tanzi RE, Lange C
published in: Human heredity
information resource reference: On the meta-analysis of genome-wide association studies: a robust and efficient approach to combine population and family-based studies. Hum Hered. 2012; 73(1):35-46.
journal title abbreviation: Hum Hered
publication date: 2012-01-18T00:00:00
year: 2012
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1122884
type: Authorship
author rank in publication: 8
linked author: Lange, Christoph
linked information resource: The Tuberculosis Network European Trials group (TBnet) ERS Clinical Research Collaboration: addressing drug-resistant tuberculosis through European cooperation.

Authorship 1123560
type: Authorship
author rank in publication: 3
linked author: Lange, Christoph
linked information resource: A comparison of popular TDT-generalizations for family-based association analysis.

A comparison of popular TDT-generalizations for family-based association analysis.
PubMed Identifier: 30609057
author list: Hecker J, Laird N, Lange C
published in: Genetic epidemiology
information resource reference: A comparison of popular TDT-generalizations for family-based association analysis. Genet Epidemiol. 2019 04; 43(3):300-317.
journal title abbreviation: Genet Epidemiol
publication date: 2019-01-04T00:00:00
year: 2019
type: Academic Article
type: Article
type: Document
type: Information Resource

The Tuberculosis Network European Trials group (TBnet) ERS Clinical Research Collaboration: addressing drug-resistant tuberculosis through European cooperation.
PubMed Identifier: 30606765
author list: van Leth F, Brinkmann F, Cirillo DM, Dheda K, Duarte R, Guglielmetti L, Kuksa L, Lange C, Mitnick C, Skrahina A, Zaman K, Bothamley G
published in: The European respiratory journal
information resource reference: The Tuberculosis Network European Trials group (TBnet) ERS Clinical Research Collaboration: addressing drug-resistant tuberculosis through European cooperation. Eur Respir J. 2019 01; 53(1).
journal title abbreviation: Eur Respir J
publication date: 2019-01-03T00:00:00
year: 2019
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CD8 T cells specific for human immunodeficiency virus, Epstein-Barr virus, and cytomegalovirus lack molecules for homing to lymphoid sites of infection.
PubMed Identifier: 11418475
author list: Chen G, Shankar P, Lange C, Valdez H, Skolnik PR, Wu L, Manjunath N, Lieberman J
published in: Blood
information resource reference: CD8 T cells specific for human immunodeficiency virus, Epstein-Barr virus, and cytomegalovirus lack molecules for homing to lymphoid sites of infection. Blood. 2001 Jul 01; 98(1):156-64.
journal title abbreviation: Blood
publication date: 2001-07-01T00:00:00
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type: Academic Article
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On the analysis of copy-number variations in genome-wide association studies: a translation of the family-based association test.
PubMed Identifier: 18228561
author list: Ionita-Laza I, Perry GH, Raby BA, Klanderman B, Lee C, Laird NM, Weiss ST, Lange C
published in: Genetic epidemiology
information resource reference: On the analysis of copy-number variations in genome-wide association studies: a translation of the family-based association test. Genet Epidemiol. 2008 Apr; 32(3):273-84.
journal title abbreviation: Genet Epidemiol
publication date: 2008-04-01T00:00:00
year: 2008
type: Academic Article
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Genomics and genome-wide association studies: an integrative approach to expression QTL mapping.
PubMed Identifier: 18586451
author list: Degnan JH, Lasky-Su J, Raby BA, Xu M, Molony C, Schadt EE, Lange C
published in: Genomics
information resource reference: Genomics and genome-wide association studies: an integrative approach to expression QTL mapping. Genomics. 2008 Sep; 92(3):129-33.
journal title abbreviation: Genomics
publication date: 2008-06-30T00:00:00
year: 2008
type: Academic Article
type: Article
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Genome-wide association analysis reveals putative Alzheimer's disease susceptibility loci in addition to APOE.
PubMed Identifier: 18976728
author list: Bertram L, Lange C, Mullin K, Parkinson M, Hsiao M, Hogan MF, Schjeide BM, Hooli B, Divito J, Ionita I, Jiang H, Laird N, Moscarillo T, Ohlsen KL, Elliott K, Wang X, Hu-Lince D, Ryder M, Murphy A, Wagner SL, Blacker D, Becker KD, Tanzi RE
published in: American journal of human genetics
information resource reference: Genome-wide association analysis reveals putative Alzheimer's disease susceptibility loci in addition to APOE. Am J Hum Genet. 2008 Nov; 83(5):623-32.
journal title abbreviation: Am J Hum Genet
publication date: 2008-10-30T00:00:00
year: 2008
type: Academic Article
type: Article
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IL1B polymorphisms modulate cystic fibrosis lung disease.
PubMed Identifier: 19431193
author list: Levy H, Murphy A, Zou F, Gerard C, Klanderman B, Schuemann B, Lazarus R, García KC, Celedón JC, Drumm M, Dahmer M, Quasney M, Schneck K, Reske M, Knowles MR, Pier GB, Lange C, Weiss ST
published in: Pediatric pulmonology
information resource reference: IL1B polymorphisms modulate cystic fibrosis lung disease. Pediatr Pulmonol. 2009 Jun; 44(6):580-93.
journal title abbreviation: Pediatr Pulmonol
publication date: 2009-06-01T00:00:00
year: 2009
type: Academic Article
type: Article
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Integration of genomic and genetic approaches implicates IREB2 as a COPD susceptibility gene.
PubMed Identifier: 19800047
author list: DeMeo DL, Mariani T, Bhattacharya S, Srisuma S, Lange C, Litonjua A, Bueno R, Pillai SG, Lomas DA, Sparrow D, Shapiro SD, Criner GJ, Kim HP, Chen Z, Choi AM, Reilly J, Silverman EK
published in: American journal of human genetics
information resource reference: Integration of genomic and genetic approaches implicates IREB2 as a COPD susceptibility gene. Am J Hum Genet. 2009 Oct; 85(4):493-502.
journal title abbreviation: Am J Hum Genet
publication date: 2009-10-01T00:00:00
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On the follow-up of genome-wide association studies: an overall test for the most promising SNPs.
PubMed Identifier: 21374717
author list: Lipman PJ, Cho MH, Bakke P, Gulsvik A, Kong X, Lomas DA, Anderson W, Silverman EK, Lange C
published in: Genetic epidemiology
information resource reference: On the follow-up of genome-wide association studies: an overall test for the most promising SNPs. Genet Epidemiol. 2011 Jul; 35(5):303-9.
journal title abbreviation: Genet Epidemiol
publication date: 2011-03-03T00:00:00
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type: Academic Article
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Genomewide association between GLCCI1 and response to glucocorticoid therapy in asthma.
PubMed Identifier: 21991891
author list: Tantisira KG, Lasky-Su J, Harada M, Murphy A, Litonjua AA, Himes BE, Lange C, Lazarus R, Sylvia J, Klanderman B, Duan QL, Qiu W, Hirota T, Martinez FD, Mauger D, Sorkness C, Szefler S, Lazarus SC, Lemanske RF, Peters SP, Lima JJ, Nakamura Y, Tamari M, Weiss ST
published in: The New England journal of medicine
information resource reference: Genomewide association between GLCCI1 and response to glucocorticoid therapy in asthma. N Engl J Med. 2011 Sep 29; 365(13):1173-83.
journal title abbreviation: N Engl J Med
publication date: 2011-09-26T00:00:00
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Resequencing of VAX1 in patients with nonsyndromic cleft lip with or without cleft palate.
PubMed Identifier: 23081944
author list: Nasser E, Mangold E, Tradowsky DC, Fier H, Becker J, Boehmer AC, Herberz R, Fricker N, Barth S, Wahle P, Nowak S, Reutter H, Reich RH, Lauster C, Braumann B, Kreusch T, Hemprich A, Pötzsch B, Hoffmann P, Kramer FJ, Knapp M, Lange C, Nöthen MM, Ludwig KU
published in: Birth defects research. Part A, Clinical and molecular teratology
information resource reference: Resequencing of VAX1 in patients with nonsyndromic cleft lip with or without cleft palate. Birth Defects Res A Clin Mol Teratol. 2012 Nov; 94(11):925-33.
journal title abbreviation: Birth Defects Res A Clin Mol Teratol
publication date: 2012-10-18T00:00:00
year: 2012
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Authorship 117618
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author rank in publication: 5
linked author: Lange, Christoph
linked information resource: An omnibus test for family-based association studies with multiple SNPs and multiple phenotypes.

Authorship 122386
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author rank in publication: 10
linked author: Lange, Christoph
linked information resource: Association of corticotropin-releasing hormone receptor-2 genetic variants with acute bronchodilator response in asthma.

Antitubercular Agents
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Authorship 1146038
type: Authorship
author rank in publication: 12
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linked information resource: Genetic Advances in Chronic Obstructive Pulmonary Disease. Insights from COPDGene.

Genetic Advances in Chronic Obstructive Pulmonary Disease. Insights from COPDGene.
PubMed Identifier: 30908940
author list: Ragland MF, Benway CJ, Lutz SM, Bowler RP, Hecker J, Hokanson JE, Crapo JD, Castaldi PJ, DeMeo DL, Hersh CP, Hobbs BD, Lange C, Beaty TH, Cho MH, Silverman EK
published in: American journal of respiratory and critical care medicine
information resource reference: Genetic Advances in Chronic Obstructive Pulmonary Disease. Insights from COPDGene. Am J Respir Crit Care Med. 2019 09 15; 200(6):677-690.
journal title abbreviation: Am J Respir Crit Care Med
publication date: 2019-09-15T00:00:00
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Mycobacterium tuberculosis
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Tuberculosis, Multidrug-Resistant
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number of publications: 1064
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Tuberculosis, Pulmonary
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number of authors: 336
number of publications: 900
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Tuberculosis
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number of authors: 605
number of publications: 2217
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Biostatistics
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Global Health and Social Medicine
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Neurology
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Nutrition
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Population Medicine
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Pulmonary
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Channing Division of Network Medicine
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Brigham and Women's Hospital
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Harvard Medical School
type: Organization

Harvard Pilgrim Healthcare
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Harvard T.H. Chan School of Public Health
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Massachusetts General Hospital
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Furin, Jennifer
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Testa, Marcia
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Wikler, Daniel I.
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Authorship 121915
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linked information resource: Mapping of numerous disease-associated expression polymorphisms in primary peripheral blood CD4+ lymphocytes.

Weiss, Scott
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Farhat, Maha
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Qi, Lu
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Laird, Nan
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Mitnick, Carole
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person in primary position: Professor of Global Heath and Social Medicine
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Authorship 130270
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author rank in publication: 25
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linked information resource: Genome-wide association scan of the time to onset of attention deficit hyperactivity disorder.

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Coull, Brent
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Williams, Paige
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Murray, Megan
eCommons Login: MBM3
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person in primary position: Ronda Stryker and William Johnston Professor of Global Health
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Authorship 138844
type: Authorship
author rank in publication: 24
linked author: Lange, Christoph
linked information resource: Genome-wide association analysis identifies PDE4D as an asthma-susceptibility gene.

Authorship 1167504
type: Authorship
author rank in publication: 6
linked author: Lange, Christoph
linked information resource: metaFARVAT: An Efficient Tool for Meta-Analysis of Family-Based, Case-Control, and Population-Based Rare Variant Association Studies.

metaFARVAT: An Efficient Tool for Meta-Analysis of Family-Based, Case-Control, and Population-Based Rare Variant Association Studies.
PubMed Identifier: 31275357
author list: Wang L, Lee S, Qiao D, Cho MH, Silverman EK, Lange C, Won S
published in: Frontiers in genetics
information resource reference: metaFARVAT: An Efficient Tool for Meta-Analysis of Family-Based, Case-Control, and Population-Based Rare Variant Association Studies. Front Genet. 2019; 10:572.
journal title abbreviation: Front Genet
publication date: 2019-06-19T00:00:00
year: 2019
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1169903
type: Authorship
author rank in publication: 11
linked author: Lange, Christoph
linked information resource: Same meat, different gravy: ignore the new names of mycobacteria.

Same meat, different gravy: ignore the new names of mycobacteria.
PubMed Identifier: 31296783
author list: Tortoli E, Brown-Elliott BA, Chalmers JD, Cirillo DM, Daley CL, Emler S, Floto RA, Garcia MJ, Hoefsloot W, Koh WJ, Lange C, Loebinger M, Maurer FP, Morimoto K, Niemann S, Richter E, Turenne CY, Vasireddy R, Vasireddy S, Wagner D, Wallace RJ, Wengenack N, van Ingen J
published in: The European respiratory journal
information resource reference: Same meat, different gravy: ignore the new names of mycobacteria. Eur Respir J. 2019 Jul; 54(1).
journal title abbreviation: Eur Respir J
publication date: 2019-07-11T00:00:00
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type: Academic Article
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Hahn, Georg
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Effect of population stratification on SNP-by-environment interaction.
PubMed Identifier: 31429121
author list: An J, Won S, Lutz SM, Hecker J, Lange C
published in: Genetic epidemiology
information resource reference: Effect of population stratification on SNP-by-environment interaction. Genet Epidemiol. 2019 12; 43(8):1046-1055.
journal title abbreviation: Genet Epidemiol
publication date: 2019-08-20T00:00:00
year: 2019
type: Academic Article
type: Article
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Authorship 156894
type: Authorship
author rank in publication: 2
linked author: Lange, Christoph
linked information resource: P2BAT: a massive parallel implementation of PBAT for genome-wide association studies in R.

Authorship 1192451
type: Authorship
author rank in publication: 30
linked author: Lange, Christoph
linked information resource: Whole Genome Sequencing Identifies CRISPLD2 as a Lung Function Gene in Children With Asthma.

Whole Genome Sequencing Identifies CRISPLD2 as a Lung Function Gene in Children With Asthma.
PubMed Identifier: 31557467
author list: Kachroo P, Hecker J, Chawes BL, Ahluwalia TS, Cho MH, Qiao D, Kelly RS, Chu SH, Virkud YV, Huang M, Barnes KC, Burchard EG, Eng C, Hu D, Celedón JC, Daya M, Levin AM, Gui H, Williams LK, Forno E, Mak ACY, Avila L, Soto-Quiros ME, Cloutier MM, Acosta-Pérez E, Canino G, Bønnelykke K, Bisgaard H, Raby BA, Lange C, Weiss ST, Lasky-Su JA
published in: Chest
information resource reference: Whole Genome Sequencing Identifies CRISPLD2 as a Lung Function Gene in Children With Asthma. Chest. 2019 12; 156(6):1068-1079.
journal title abbreviation: Chest
publication date: 2019-09-23T00:00:00
year: 2019
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 150891
type: Authorship
author rank in publication: 5
linked author: Lange, Christoph
linked information resource: Inferring genetic causal effects on survival data with associated endo-phenotypes.

Authorship 143502
type: Authorship
author rank in publication: 2
linked author: Lange, Christoph
linked information resource: PBAT: a comprehensive software package for genome-wide association analysis of complex family-based studies.

Authorship 162729
type: Authorship
author rank in publication: 9
linked author: Lange, Christoph
linked information resource: Assessing the reproducibility of asthma candidate gene associations, using genome-wide data.

Authorship 152161
type: Authorship
author rank in publication: 5
linked author: Lange, Christoph
linked information resource: Increased expression of the natural killer cell inhibitory receptor CD85j/ILT2 on antigen-specific effector CD8 T cells and its impact on CD8 T-cell function.

Authorship 12587
type: Authorship
author rank in publication: 9
linked author: Lange, Christoph
linked information resource: Polymorphisms in toll-like receptor 4 are not associated with asthma or atopy-related phenotypes.

Authorship 1204737
type: Authorship
author rank in publication: 6
linked author: Lange, Christoph
linked information resource: A flexible and nearly optimal sequential testing approach to randomized testing: QUICK-STOP.

A flexible and nearly optimal sequential testing approach to randomized testing: QUICK-STOP.
PubMed Identifier: 31713269
author list: Hecker J, Ruczinski I, Cho MH, Silverman EK, Coull B, Lange C
published in: Genetic epidemiology
information resource reference: A flexible and nearly optimal sequential testing approach to randomized testing: QUICK-STOP. Genet Epidemiol. 2020 03; 44(2):139-147.
journal title abbreviation: Genet Epidemiol
publication date: 2019-11-11T00:00:00
year: 2019
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 123978
type: Authorship
author rank in publication: 4
linked author: Lange, Christoph
linked information resource: Genomewide weighted hypothesis testing in family-based association studies, with an application to a 100K scan.

A standardised method for interpreting the association between mutations and phenotypic drug resistance in Mycobacterium tuberculosis.
PubMed Identifier: 29284687
author list: Miotto P, Tessema B, Tagliani E, Chindelevitch L, Starks AM, Emerson C, Hanna D, Kim PS, Liwski R, Zignol M, Gilpin C, Niemann S, Denkinger CM, Fleming J, Warren RM, Crook D, Posey J, Gagneux S, Hoffner S, Rodrigues C, Comas I, Engelthaler DM, Murray M, Alland D, Rigouts L, Lange C, Dheda K, Hasan R, Ranganathan UDK, McNerney R, Ezewudo M, Cirillo DM, Schito M, Köser CU, Rodwell TC
published in: The European respiratory journal
information resource reference: A standardised method for interpreting the association between mutations and phenotypic drug resistance in Mycobacterium tuberculosis. Eur Respir J. 2017 12; 50(6).
journal title abbreviation: Eur Respir J
publication date: 2017-12-28T00:00:00
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type: Academic Article
type: Article
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Authorship 122767
type: Authorship
author rank in publication: 10
linked author: Lange, Christoph
linked information resource: 'Location, Location, Location': a spatial approach for rare variant analysis and an application to a study on non-syndromic cleft lip with or without cleft palate.

Authorship 1233774
type: Authorship
author rank in publication: 5
linked author: Lange, Christoph
linked information resource: The effects of misspecification of the mediator and outcome in mediation analysis.

Authorship 1232308
type: Authorship
author rank in publication: 11
linked author: Lange, Christoph
linked information resource: Identification of Novel Alzheimer's Disease Loci Using Sex-Specific Family-Based Association Analysis of Whole-Genome Sequence Data.

Identification of Novel Alzheimer's Disease Loci Using Sex-Specific Family-Based Association Analysis of Whole-Genome Sequence Data.
PubMed Identifier: 32193444
author list: Prokopenko D, Hecker J, Kirchner R, Chapman BA, Hoffman O, Mullin K, Hide W, Bertram L, Laird N, DeMeo DL, Lange C, Tanzi RE
published in: Scientific reports
information resource reference: Identification of Novel Alzheimer's Disease Loci Using Sex-Specific Family-Based Association Analysis of Whole-Genome Sequence Data. Sci Rep. 2020 03 19; 10(1):5029.
journal title abbreviation: Sci Rep
publication date: 2020-03-19T00:00:00
year: 2020
type: Academic Article
type: Article
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The effects of misspecification of the mediator and outcome in mediation analysis.
PubMed Identifier: 32166765
author list: Lutz SM, Sordillo JE, Hokanson JE, Chen Wu A, Lange C
published in: Genetic epidemiology
information resource reference: The effects of misspecification of the mediator and outcome in mediation analysis. Genet Epidemiol. 2020 06; 44(4):400-403.
journal title abbreviation: Genet Epidemiol
publication date: 2020-03-13T00:00:00
year: 2020
type: Academic Article
type: Article
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Authorship 16731
type: Authorship
author rank in publication: 15
linked author: Lange, Christoph
linked information resource: ARG1 is a novel bronchodilator response gene: screening and replication in four asthma cohorts.

Authorship 174236
type: Authorship
author rank in publication: 2
linked author: Lange, Christoph
linked information resource: The transforming growth factor-beta1 (TGFB1) gene is associated with chronic obstructive pulmonary disease (COPD).

Authorship 1264736
type: Authorship
author rank in publication: 5
linked author: Lange, Christoph
linked information resource: https://connects.catalyst.harvard.edu/Profiles/profile/157288476

Authorship 1265525
type: Authorship
author rank in publication: 4
linked author: Lange, Christoph
linked information resource: Unsupervised cluster analysis of SARS-CoV-2 genomes reflects its geographic progression and identifies distinct genetic subgroups of SARS-CoV-2 virus.

Unsupervised cluster analysis of SARS-CoV-2 genomes reflects its geographic progression and identifies distinct genetic subgroups of SARS-CoV-2 virus.
PubMed Identifier: 32637949
author list: Hahn G, Lee S, Weiss ST, Lange C
published in: bioRxiv : the preprint server for biology
information resource reference: Unsupervised cluster analysis of SARS-CoV-2 genomes reflects its geographic progression and identifies distinct genetic subgroups of SARS-CoV-2 virus. bioRxiv. 2020 Nov 20.
journal title abbreviation: bioRxiv
publication date: 2020-11-20T00:00:00
year: 2020
type: Academic Article
type: Article
type: Document
type: Information Resource

https://connects.catalyst.harvard.edu/Profiles/profile/157288476
PubMed Identifier: 32637951
author list: Hahn G, Cho MH, Weiss ST, Silverman EK, Lange C
published in: bioRxiv : the preprint server for biology
information resource reference: Unsupervised cluster analysis of SARS-CoV-2 genomes indicates that recent (June 2020) cases in Beijing are from a genetic subgroup that consists of mostly European and South(east) Asian samples, of which the latter are the most recent. bioRxiv. 2020 Jun 30.
journal title abbreviation: bioRxiv
publication date: 2020-06-30T00:00:00
year: 2020
type: Academic Article
type: Article
type: Document
type: Information Resource
label: Unsupervised cluster analysis of SARS-CoV-2 genomes indicates that recent (June 2020) cases in Beijing are from a genetic subgroup that consists of mostly European and South(east) Asian samples, of which the latter are the most recent.

Authorship 148831
type: Authorship
author rank in publication: 3
linked author: Lange, Christoph
linked information resource: Susceptibility to tuberculosis is associated with TLR1 polymorphisms resulting in a lack of TLR1 cell surface expression.

Authorship 1280667
type: Authorship
author rank in publication: 3
linked author: Lange, Christoph
linked information resource: A novel locus for exertional dyspnoea in childhood asthma.

A novel locus for exertional dyspnoea in childhood asthma.
PubMed Identifier: 32855217
author list: Lee S, Lasky-Su JA, Lange C, Kim W, Kumar PL, McDonald MN, Vaz Fragoso CA, Laurie C, Raby BA, Celedón JC, Cho MH, Won S, Weiss ST, Hecker J
published in: The European respiratory journal
information resource reference: A novel locus for exertional dyspnoea in childhood asthma. Eur Respir J. 2021 02; 57(2).
journal title abbreviation: Eur Respir J
publication date: 2021-02-04T00:00:00
year: 2021
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 186039
type: Authorship
author rank in publication: 16
linked author: Lange, Christoph
linked information resource: Dissecting direct and indirect genetic effects on chronic obstructive pulmonary disease (COPD) susceptibility.

Authorship 1284642
type: Authorship
author rank in publication: 8
linked author: Lange, Christoph
linked information resource: locStra: Fast analysis of regional/global stratification in whole-genome sequencing studies.

Authorship 1284672
type: Authorship
author rank in publication: 7
linked author: Lange, Christoph
linked information resource: An interaction of the 17q12-21 locus with mold exposure in childhood asthma.

locStra: Fast analysis of regional/global stratification in whole-genome sequencing studies.
PubMed Identifier: 32929743
author list: Hahn G, Lutz SM, Hecker J, Prokopenko D, Cho MH, Silverman EK, Weiss ST, Lange C
published in: Genetic epidemiology
information resource reference: locStra: Fast analysis of regional/global stratification in whole-genome sequencing studies. Genet Epidemiol. 2021 02; 45(1):82-98.
journal title abbreviation: Genet Epidemiol
publication date: 2020-09-14T00:00:00
year: 2020
type: Academic Article
type: Article
type: Document
type: Information Resource

An interaction of the 17q12-21 locus with mold exposure in childhood asthma.
PubMed Identifier: 32946604
author list: Lee S, Lasky-Su J, Kim W, Won S, Laurie C, Celedón JC, Lange C, Weiss ST, Hecker J
published in: Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology
information resource reference: An interaction of the 17q12-21 locus with mold exposure in childhood asthma. Pediatr Allergy Immunol. 2021 02; 32(2):373-376.
journal title abbreviation: Pediatr Allergy Immunol
publication date: 2020-10-13T00:00:00
year: 2020
type: Academic Article
type: Article
type: Document
type: Information Resource

Global Health and Population
type: Department
type: Organization

Authorship 230777
type: Authorship
author rank in publication: 2
linked author: Lange, Christoph
linked information resource: CGene: an R package for implementation of causal genetic analyses.

Whole-genome sequencing reveals new Alzheimer's disease-associated rare variants in loci related to synaptic function and neuronal development.
PubMed Identifier: 33173892
author list: Prokopenko D, Morgan SL, Mullin K, Hofmann O, Chapman B, Kirchner R, Amberkar S, Wohlers I, Lange C, Hide W, Bertram L, Tanzi RE
published in: medRxiv : the preprint server for health sciences
information resource reference: Whole-genome sequencing reveals new Alzheimer's disease-associated rare variants in loci related to synaptic function and neuronal development. medRxiv. 2020 Nov 04.
journal title abbreviation: medRxiv
publication date: 2020-11-04T00:00:00
year: 2020
type: Academic Article
type: Article
type: Document
type: Information Resource

https://connects.catalyst.harvard.edu/Profiles/profile/172600180
type: URLLink
label: https://www.hsph.harvard.edu/christoph-lange/
link anchor text: Faculty Website

Authorship 1314329
type: Authorship
author rank in publication: 10
linked author: Lange, Christoph
linked information resource: A unifying framework for rare variant association testing in family-based designs, including higher criticism approaches, SKATs, and burden tests.

A unifying framework for rare variant association testing in family-based designs, including higher criticism approaches, SKATs, and burden tests.
PubMed Identifier: 33367522
author list: Hecker J, Townes FW, Kachroo P, Laurie C, Lasky-Su J, Ziniti J, Cho MH, Weiss ST, Laird NM, Lange C
published in: Bioinformatics (Oxford, England)
information resource reference: A unifying framework for rare variant association testing in family-based designs, including higher criticism approaches, SKATs, and burden tests. Bioinformatics. 2021 Apr 01; 36(22-23):5432-5438.
journal title abbreviation: Bioinformatics
publication date: 2021-04-01T00:00:00
year: 2021
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1316637
type: Authorship
author rank in publication: 4
linked author: Lange, Christoph
linked information resource: Unsupervised cluster analysis of SARS-CoV-2 genomes reflects its geographic progression and identifies distinct genetic subgroups of SARS-CoV-2 virus.

Unsupervised cluster analysis of SARS-CoV-2 genomes reflects its geographic progression and identifies distinct genetic subgroups of SARS-CoV-2 virus.
PubMed Identifier: 33415739
author list: Hahn G, Lee S, Weiss ST, Lange C
published in: Genetic epidemiology
information resource reference: Unsupervised cluster analysis of SARS-CoV-2 genomes reflects its geographic progression and identifies distinct genetic subgroups of SARS-CoV-2 virus. Genet Epidemiol. 2021 04; 45(3):316-323.
journal title abbreviation: Genet Epidemiol
publication date: 2021-01-08T00:00:00
year: 2021
type: Academic Article
type: Article
type: Document
type: Information Resource

Whole-genome sequencing reveals new Alzheimer's disease-associated rare variants in loci related to synaptic function and neuronal development.
PubMed Identifier: 33797837
author list: Prokopenko D, Morgan SL, Mullin K, Hofmann O, Chapman B, Kirchner R, Amberkar S, Wohlers I, Lange C, Hide W, Bertram L, Tanzi RE
published in: Alzheimer's & dementia : the journal of the Alzheimer's Association
information resource reference: Whole-genome sequencing reveals new Alzheimer's disease-associated rare variants in loci related to synaptic function and neuronal development. Alzheimers Dement. 2021 09; 17(9):1509-1527.
journal title abbreviation: Alzheimers Dement
publication date: 2021-04-02T00:00:00
year: 2021
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1348895
type: Authorship
author rank in publication: 6
linked author: Lange, Christoph
linked information resource: Novel recessive locus for body mass index in childhood asthma.

Novel recessive locus for body mass index in childhood asthma.
PubMed Identifier: 33888571
author list: Lee S, Lasky-Su J, Won S, Laurie C, Celedón JC, Lange C, Weiss S, Hecker J
published in: Thorax
information resource reference: Novel recessive locus for body mass index in childhood asthma. Thorax. 2021 12; 76(12):1227-1230.
journal title abbreviation: Thorax
publication date: 2021-04-22T00:00:00
year: 2021
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1354588
type: Authorship
author rank in publication: 5
linked author: Lange, Christoph
linked information resource: Caution against examining the role of reverse causality in Mendelian Randomization.

Caution against examining the role of reverse causality in Mendelian Randomization.
PubMed Identifier: 34008876
author list: Lutz SM, Wu AC, Hokanson JE, Vansteelandt S, Lange C
published in: Genetic epidemiology
information resource reference: Caution against examining the role of reverse causality in Mendelian Randomization. Genet Epidemiol. 2021 07; 45(5):445-454.
journal title abbreviation: Genet Epidemiol
publication date: 2021-05-19T00:00:00
year: 2021
type: Academic Article
type: Article
type: Document
type: Information Resource

Genome-wide association analysis of COVID-19 mortality risk in SARS-CoV-2 genomes identifies mutation in the SARS-CoV-2 spike protein that colocalizes with P.1 of the Brazilian strain.
PubMed Identifier: 34159627
author list: Hahn G, Wu CM, Lee S, Lutz SM, Khurana S, Baden LR, Haneuse S, Qiao D, Hecker J, DeMeo DL, Tanzi RE, Choudhary MC, Etemad B, Mohammadi A, Esmaeilzadeh E, Cho MH, Li JZ, Randolph AG, Laird NM, Weiss ST, Silverman EK, Ribbeck K, Lange C
published in: Genetic epidemiology
information resource reference: Genome-wide association analysis of COVID-19 mortality risk in SARS-CoV-2 genomes identifies mutation in the SARS-CoV-2 spike protein that colocalizes with P.1 of the Brazilian strain. Genet Epidemiol. 2021 10; 45(7):685-693.
journal title abbreviation: Genet Epidemiol
publication date: 2021-06-22T00:00:00
year: 2021
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1373119
type: Authorship
author rank in publication: 23
linked author: Lange, Christoph
linked information resource: Genome-wide association analysis of COVID-19 mortality risk in SARS-CoV-2 genomes identifies mutation in the SARS-CoV-2 spike protein that colocalizes with P.1 of the Brazilian strain.

Authorship 177339
type: Authorship
author rank in publication: 2
linked author: Lange, Christoph
linked information resource: Causation and causal inference for genetic effects.

A Smoothed Version of the Lassosum Penalty for Fitting Integrated Risk Models Using Summary Statistics or Individual-Level Data.
PubMed Identifier: 35052450
author list: Hahn G, Prokopenko D, Lutz SM, Mullin K, Tanzi RE, Cho MH, Silverman EK, Lange C
published in: Genes
information resource reference: A Smoothed Version of the Lassosum Penalty for Fitting Integrated Risk Models Using Summary Statistics or Individual-Level Data. Genes (Basel). 2022 01 06; 13(1).
journal title abbreviation: Genes (Basel)
publication date: 2022-01-06T00:00:00
year: 2022
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1424792
type: Authorship
author rank in publication: 8
linked author: Lange, Christoph
linked information resource: A Smoothed Version of the Lassosum Penalty for Fitting Integrated Risk Models Using Summary Statistics or Individual-Level Data.

Reply to Neupane et al.: Replication study of AD-associated rare variants.
PubMed Identifier: 35142036
author list: Prokopenko D, Morgan SL, Lange C, Hide W, Bertram L, Tanzi RE
published in: Alzheimer's & dementia : the journal of the Alzheimer's Association
information resource reference: Reply to Neupane et al.: Replication study of AD-associated rare variants. Alzheimers Dement. 2022 04; 18(4):863-864.
journal title abbreviation: Alzheimers Dement
publication date: 2022-02-09T00:00:00
year: 2022
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1436537
type: Authorship
author rank in publication: 13
linked author: Lange, Christoph
linked information resource: Region-based analysis of rare genomic variants in whole-genome sequencing datasets reveal two novel Alzheimer's disease-associated genes: DTNB and DLG2.

Authorship 1441168
type: Authorship
author rank in publication: 6
linked author: Lange, Christoph
linked information resource: The influence of unmeasured confounding on the MR Steiger approach.

The influence of unmeasured confounding on the MR Steiger approach.
PubMed Identifier: 35170805
author list: Lutz SM, Voorhies K, Wu AC, Hokanson J, Vansteelandt S, Lange C
published in: Genetic epidemiology
information resource reference: The influence of unmeasured confounding on the MR Steiger approach. Genet Epidemiol. 2022 03; 46(2):139-141.
journal title abbreviation: Genet Epidemiol
publication date: 2022-02-16T00:00:00
year: 2022
type: Academic Article
type: Article
type: Document
type: Information Resource

Region-based analysis of rare genomic variants in whole-genome sequencing datasets reveal two novel Alzheimer's disease-associated genes: DTNB and DLG2.
PubMed Identifier: 35246634
author list: Prokopenko D, Lee S, Hecker J, Mullin K, Morgan S, Katsumata Y, Weiner MW, Fardo DW, Laird N, Bertram L, Hide W, Lange C, Tanzi RE
published in: Molecular psychiatry
information resource reference: Region-based analysis of rare genomic variants in whole-genome sequencing datasets reveal two novel Alzheimer's disease-associated genes: DTNB and DLG2. Mol Psychiatry. 2022 04; 27(4):1963-1969.
journal title abbreviation: Mol Psychiatry
publication date: 2022-03-04T00:00:00
year: 2022
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 295125
type: Authorship
author rank in publication: 7
linked author: Lange, Christoph
linked information resource: Genomic screening in family-based association testing.

Authorship 1446312
type: Authorship
author rank in publication: 6
linked author: Lange, Christoph
linked information resource: Selection bias when inferring the effect direction in Mendelian randomization.

Selection bias when inferring the effect direction in Mendelian randomization.
PubMed Identifier: 35500225
author list: Lutz SM, Voorhies K, Wu AC, Hokanson J, Vansteelandt S, Lange C
published in: Genetic epidemiology
information resource reference: Selection bias when inferring the effect direction in Mendelian randomization. Genet Epidemiol. 2022 07; 46(5-6):341-343.
journal title abbreviation: Genet Epidemiol
publication date: 2022-05-02T00:00:00
year: 2022
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1450895
type: Authorship
author rank in publication: 11
linked author: Lange, Christoph
linked information resource: Covariate adjustment of spirometric and smoking phenotypes: The potential of neural network models.

Covariate adjustment of spirometric and smoking phenotypes: The potential of neural network models.
PubMed Identifier: 35544468
author list: Voorhies K, Bie R, Hokanson JE, Weiss ST, Chen Wu A, Hecker J, Hahn G, Demeo DL, Silverman E, Cho MH, Lange C, Lutz SM
published in: PloS one
information resource reference: Covariate adjustment of spirometric and smoking phenotypes: The potential of neural network models. PLoS One. 2022; 17(5):e0266752.
journal title abbreviation: PLoS One
publication date: 2022-05-11T00:00:00
year: 2022
type: Academic Article
type: Article
type: Document
type: Information Resource

Cross-reactive immunity against the SARS-CoV-2 Omicron variant is low in pediatric patients with prior COVID-19 or MIS-C.
PubMed Identifier: 35624101
author list: Tang J, Novak T, Hecker J, Grubbs G, Zahra FT, Bellusci L, Pourhashemi S, Chou J, Moffitt K, Halasa NB, Schwartz SP, Walker TC, Tarquinio KM, Zinter MS, Staat MA, Gertz SJ, Cvijanovich NZ, Schuster JE, Loftis LL, Coates BM, Mack EH, Irby K, Fitzgerald JC, Rowan CM, Kong M, Flori HR, Maddux AB, Shein SL, Crandall H, Hume JR, Hobbs CV, Tremoulet AH, Shimizu C, Burns JC, Chen SR, Moon HK, Lange C, Randolph AG, Khurana S
published in: Nature communications
information resource reference: Cross-reactive immunity against the SARS-CoV-2 Omicron variant is low in pediatric patients with prior COVID-19 or MIS-C. Nat Commun. 2022 05 27; 13(1):2979.
journal title abbreviation: Nat Commun
publication date: 2022-05-27T00:00:00
year: 2022
type: Academic Article
type: Article
type: Document
type: Information Resource

Development and validation of a trans-ancestry polygenic risk score for type 2 diabetes in diverse populations.
PubMed Identifier: 35765100
author list: Ge T, Irvin MR, Patki A, Srinivasasainagendra V, Lin YF, Tiwari HK, Armstrong ND, Benoit B, Chen CY, Choi KW, Cimino JJ, Davis BH, Dikilitas O, Etheridge B, Feng YA, Gainer V, Huang H, Jarvik GP, Kachulis C, Kenny EE, Khan A, Kiryluk K, Kottyan L, Kullo IJ, Lange C, Lennon N, Leong A, Malolepsza E, Miles AD, Murphy S, Namjou B, Narayan R, O'Connor MJ, Pacheco JA, Perez E, Rasmussen-Torvik LJ, Rosenthal EA, Schaid D, Stamou M, Udler MS, Wei WQ, Weiss ST, Ng MCY, Smoller JW, Lebo MS, Meigs JB, Limdi NA, Karlson EW
published in: Genome medicine
information resource reference: Development and validation of a trans-ancestry polygenic risk score for type 2 diabetes in diverse populations. Genome Med. 2022 06 29; 14(1):70.
journal title abbreviation: Genome Med
publication date: 2022-06-29T00:00:00
year: 2022
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1467614
type: Authorship
author rank in publication: 20
linked author: Lange, Christoph
linked information resource: Assessing the contribution of rare genetic variants to phenotypes of chronic obstructive pulmonary disease using whole-genome sequence data.

Authorship 1467462
type: Authorship
author rank in publication: 25
linked author: Lange, Christoph
linked information resource: Development and validation of a trans-ancestry polygenic risk score for type 2 diabetes in diverse populations.

Assessing the contribution of rare genetic variants to phenotypes of chronic obstructive pulmonary disease using whole-genome sequence data.
PubMed Identifier: 35766891
author list: Kim W, Hecker J, Barr RG, Boerwinkle E, Cade B, Correa A, Dupuis J, Gharib SA, Lange L, London SJ, Morrison AC, O'Connor GT, Oelsner EC, Psaty BM, Vasan RS, Redline S, Rich SS, Rotter JI, Yu B, Lange C, Manichaikul A, Zhou JJ, Sofer T, Silverman EK, Qiao D, Cho MH
published in: Human molecular genetics
information resource reference: Assessing the contribution of rare genetic variants to phenotypes of chronic obstructive pulmonary disease using whole-genome sequence data. Hum Mol Genet. 2022 11 10; 31(22):3873-3885.
journal title abbreviation: Hum Mol Genet
publication date: 2022-11-10T00:00:00
year: 2022
type: Academic Article
type: Article
type: Document
type: Information Resource

Author Correction: Cross-reactive immunity against the SARS-CoV-2 Omicron variant is low in pediatric patients with prior COVID-19 or MIS-C.
PubMed Identifier: 35961980
author list: Tang J, Novak T, Hecker J, Grubbs G, Zahra FT, Bellusci L, Pourhashemi S, Chou J, Moffitt K, Halasa NB, Schwartz SP, Walker TC, Tarquinio KM, Zinter MS, Staat MA, Gertz SJ, Cvijanovich NZ, Schuster JE, Loftis LL, Coates BM, Mack EH, Irby K, Fitzgerald JC, Rowan CM, Kong M, Flori HR, Maddux AB, Shein SL, Crandall H, Hume JR, Hobbs CV, Tremoulet AH, Shimizu C, Burns JC, Chen SR, Moon HK, Lange C, Randolph AG, Khurana S
published in: Nature communications
information resource reference: Author Correction: Cross-reactive immunity against the SARS-CoV-2 Omicron variant is low in pediatric patients with prior COVID-19 or MIS-C. Nat Commun. 2022 Aug 12; 13(1):4732.
journal title abbreviation: Nat Commun
publication date: 2022-08-12T00:00:00
year: 2022
type: Academic Article
type: Article
type: Document
type: Information Resource

DDX58 Is Associated With Susceptibility to Severe Influenza Virus Infection in Children and Adolescents.
PubMed Identifier: 35986912
author list: Lee S, Zhang Y, Newhams M, Novak T, Thomas PG, Mourani PM, Hall MW, Loftis LL, Cvijanovich NZ, Tarquinio KM, Schwarz AJ, Weiss SL, Thomas NJ, Markovitz B, Cullimore ML, Sanders RC, Zinter MS, Sullivan JE, Halasa NB, Bembea MM, Giuliano JS, Typpo KV, Nofziger RA, Shein SL, Kong M, Coates BM, Weiss ST, Lange C, Su HC, Randolph AG
published in: The Journal of infectious diseases
information resource reference: DDX58 Is Associated With Susceptibility to Severe Influenza Virus Infection in Children and Adolescents. J Infect Dis. 2022 11 28; 226(11):2030-2036.
journal title abbreviation: J Infect Dis
publication date: 2022-11-28T00:00:00
year: 2022
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1478181
type: Authorship
author rank in publication: 28
linked author: Lange, Christoph
linked information resource: DDX58 Is Associated With Susceptibility to Severe Influenza Virus Infection in Children and Adolescents.

Authorship 1491704
type: Authorship
author rank in publication: 9
linked author: Lange, Christoph
linked information resource: Zinc finger protein 33B demonstrates sex interaction with atopy-related markers in childhood asthma.

Authorship 1489893
type: Authorship
author rank in publication: 21
linked author: Lange, Christoph
linked information resource: FGF20 and PGM2 variants are associated with childhood asthma in family-based whole-genome sequencing studies.

FGF20 and PGM2 variants are associated with childhood asthma in family-based whole-genome sequencing studies.
PubMed Identifier: 36255742
author list: Hecker J, Chun S, Samiei A, Liu C, Laurie C, Kachroo P, Lutz SM, Lee S, Smith AV, Lasky-Su J, Cho MH, Sharma S, Soto Quirós ME, Avila L, Celedón JC, Raby B, Zhou X, Silverman EK, DeMeo DL, Lange C, Weiss ST
published in: Human molecular genetics
information resource reference: FGF20 and PGM2 variants are associated with childhood asthma in family-based whole-genome sequencing studies. Hum Mol Genet. 2023 01 27; 32(4):696-707.
journal title abbreviation: Hum Mol Genet
publication date: 2023-01-27T00:00:00
year: 2023
type: Academic Article
type: Article
type: Document
type: Information Resource

Zinc finger protein 33B demonstrates sex interaction with atopy-related markers in childhood asthma.
PubMed Identifier: 35953101
author list: Lee S, Prokopenko D, Kelly RS, Lutz S, Ann Lasky-Su J, Cho MH, Laurie C, Celedón JC, Lange C, Weiss ST, Hecker J, DeMeo DL
published in: The European respiratory journal
information resource reference: Zinc finger protein 33B demonstrates sex interaction with atopy-related markers in childhood asthma. Eur Respir J. 2023 01; 61(1).
journal title abbreviation: Eur Respir J
publication date: 2023-01-06T00:00:00
year: 2023
type: Academic Article
type: Article
type: Document
type: Information Resource

A robust and adaptive framework for interaction testing in quantitative traits between multiple genetic loci and exposure variables.
PubMed Identifier: 36383614
author list: Hecker J, Prokopenko D, Moll M, Lee S, Kim W, Qiao D, Voorhies K, Kim W, Vansteelandt S, Hobbs BD, Cho MH, Silverman EK, Lutz SM, DeMeo DL, Weiss ST, Lange C
published in: PLoS genetics
information resource reference: A robust and adaptive framework for interaction testing in quantitative traits between multiple genetic loci and exposure variables. PLoS Genet. 2022 11; 18(11):e1010464.
journal title abbreviation: PLoS Genet
publication date: 2022-11-16T00:00:00
year: 2022
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1504103
type: Authorship
author rank in publication: 16
linked author: Lange, Christoph
linked information resource: A robust and adaptive framework for interaction testing in quantitative traits between multiple genetic loci and exposure variables.

Optimizing DNA Extraction from Pediatric Stool for Diagnosis of Tuberculosis and Use in Next-Generation Sequencing Applications.
PubMed Identifier: 36475757
author list: Ness TE, Meiwes L, Kay A, Mejia R, Lange C, Farhat M, Mandalakas A, DiNardo A
published in: Microbiology spectrum
information resource reference: Optimizing DNA Extraction from Pediatric Stool for Diagnosis of Tuberculosis and Use in Next-Generation Sequencing Applications. Microbiol Spectr. 2023 02 14; 11(1):e0226922.
journal title abbreviation: Microbiol Spectr
publication date: 2022-12-08T00:00:00
year: 2022
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1511126
type: Authorship
author rank in publication: 12
linked author: Lange, Christoph
linked information resource: Unsupervised outlier detection applied to SARS-CoV-2 nucleotide sequences can identify sequences of common variants and other variants of interest.

Authorship 1513266
type: Authorship
author rank in publication: 11
linked author: Lange, Christoph
linked information resource: A comparison between similarity matrices for principal component analysis to assess population stratification in sequenced genetic data sets.

Unsupervised outlier detection applied to SARS-CoV-2 nucleotide sequences can identify sequences of common variants and other variants of interest.
PubMed Identifier: 36536276
author list: Hahn G, Lee S, Prokopenko D, Abraham J, Novak T, Hecker J, Cho M, Khurana S, Baden LR, Randolph AG, Weiss ST, Lange C
published in: BMC bioinformatics
information resource reference: Unsupervised outlier detection applied to SARS-CoV-2 nucleotide sequences can identify sequences of common variants and other variants of interest. BMC Bioinformatics. 2022 Dec 19; 23(1):547.
journal title abbreviation: BMC Bioinformatics
publication date: 2022-12-19T00:00:00
year: 2022
type: Academic Article
type: Article
type: Document
type: Information Resource

A comparison between similarity matrices for principal component analysis to assess population stratification in sequenced genetic data sets.
PubMed Identifier: 36585781
author list: Lee S, Hahn G, Hecker J, Lutz SM, Mullin K, Hide W, Bertram L, DeMeo DL, Tanzi RE, Lange C, Prokopenko D
published in: Briefings in bioinformatics
information resource reference: A comparison between similarity matrices for principal component analysis to assess population stratification in sequenced genetic data sets. Brief Bioinform. 2023 01 19; 24(1).
journal title abbreviation: Brief Bioinform
publication date: 2023-01-19T00:00:00
year: 2023
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 210821
type: Authorship
author rank in publication: 3
linked author: Lange, Christoph
linked information resource: Recommendations for using standardised phenotypes in genetic association studies.

Authorship 1522110
type: Authorship
author rank in publication: 14
linked author: Lange, Christoph
linked information resource: X chromosome associations with chronic obstructive pulmonary disease and related phenotypes: an X chromosome-wide association study.

X chromosome associations with chronic obstructive pulmonary disease and related phenotypes: an X chromosome-wide association study.
PubMed Identifier: 36726148
author list: Hayden LP, Hobbs BD, Busch R, Cho MH, Liu M, Lopes-Ramos CM, Lomas DA, Bakke P, Gulsvik A, Silverman EK, Crapo JD, Beaty TH, Laird NM, Lange C, DeMeo DL
published in: Respiratory research
information resource reference: X chromosome associations with chronic obstructive pulmonary disease and related phenotypes: an X chromosome-wide association study. Respir Res. 2023 Feb 01; 24(1):38.
journal title abbreviation: Respir Res
publication date: 2023-02-01T00:00:00
year: 2023
type: Academic Article
type: Article
type: Document
type: Information Resource

The Role of Sex in Genetic Association Studies of Depression.
PubMed Identifier: 36741030
author list: Hoth KF, Voorhies K, Wu AC, Lange C, Potash JB, Lutz SM
published in: Journal of psychiatry and brain science
information resource reference: The Role of Sex in Genetic Association Studies of Depression. J Psychiatr Brain Sci. 2022; 7(6).
journal title abbreviation: J Psychiatr Brain Sci
publication date: 2022-12-30T00:00:00
year: 2022
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 203311
type: Authorship
author rank in publication: 7
linked author: Lange, Christoph
linked information resource: Genomics and genome-wide association studies: an integrative approach to expression QTL mapping.

Authorship 495872
type: Authorship
author rank in publication: 5
linked author: Lange, Christoph
linked information resource: Recovering unused information in genome-wide association studies: the benefit of analyzing SNPs out of Hardy-Weinberg equilibrium.

Authorship 1572932
type: Authorship
author rank in publication: 5
linked author: Lange, Christoph
linked information resource: Longitudinal Analysis of Contrasts in Gene Expression Data.

Longitudinal Analysis of Contrasts in Gene Expression Data.
PubMed Identifier: 37372314
author list: Hahn G, Novak T, Crawford JC, Randolph AG, Lange C
published in: Genes
information resource reference: Longitudinal Analysis of Contrasts in Gene Expression Data. Genes (Basel). 2023 05 24; 14(6).
journal title abbreviation: Genes (Basel)
publication date: 2023-05-24T00:00:00
year: 2023
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 220287
type: Authorship
author rank in publication: 3
linked author: Lange, Christoph
linked information resource: Combining disease models to test for gene-environment interaction in nuclear families.

Authorship 222687
type: Authorship
author rank in publication: 2
linked author: Lange, Christoph
linked information resource: Univariate and multivariate family-based association analysis of the IL-13 ARG130GLN polymorphism in the Childhood Asthma Management Program.

Authorship 224596
type: Authorship
author rank in publication: 33
linked author: Lange, Christoph
linked information resource: On the replication of genetic associations: timing can be everything!

Authorship 1589219
type: Authorship
author rank in publication: 11
linked author: Lange, Christoph
linked information resource: A consistent pattern of slide effects in Illumina DNA methylation BeadChip array data.

A consistent pattern of slide effects in Illumina DNA methylation BeadChip array data.
PubMed Identifier: 37731367
author list: Hecker J, Lee S, Kachroo P, Prokopenko D, Maaser-Hecker A, Lutz SM, Hahn G, Irizarry R, Weiss ST, DeMeo DL, Lange C
published in: Epigenetics
information resource reference: A consistent pattern of slide effects in Illumina DNA methylation BeadChip array data. Epigenetics. 2023 12; 18(1):2257437.
journal title abbreviation: Epigenetics
publication date: 2023-09-20T00:00:00
year: 2023
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 392386
type: Authorship
author rank in publication: 3
linked author: Lange, Christoph
linked information resource: The SERPINE2 gene is associated with chronic obstructive pulmonary disease.

Lecturer on Global Health and Social Medicine, Part-time
is primary position: true
position in department: Global Health and Social Medicine
position in division: https://connects.catalyst.harvard.edu/Profiles/profile/1229413
sort order: 1
type: Position
HR job title: Lecturer on Global Health and Social Medicine, Part-time
position in organization: Harvard Medical School

Professor of Global Heath and Social Medicine
is primary position: true
position in department: Global Health and Social Medicine
position in division: https://connects.catalyst.harvard.edu/Profiles/profile/1229413
sort order: 1
type: Position
HR job title: Professor of Global Heath and Social Medicine
position in organization: Harvard Medical School

Authorship 1623988
type: Authorship
author rank in publication: 8
linked author: Lange, Christoph
linked information resource: Fast computation of the eigensystem of genomic similarity matrices.

Fast computation of the eigensystem of genomic similarity matrices.
PubMed Identifier: 38273228
author list: Hahn G, Lutz SM, Hecker J, Prokopenko D, Cho MH, Silverman EK, Weiss ST, Lange C
published in: BMC bioinformatics
information resource reference: Fast computation of the eigensystem of genomic similarity matrices. BMC Bioinformatics. 2024 Jan 25; 25(1):43.
journal title abbreviation: BMC Bioinformatics
publication date: 2024-01-25T00:00:00
year: 2024
type: Academic Article
type: Article
type: Document
type: Information Resource

Multidrug-resistant tuberculosis.
PubMed Identifier: 38523140
author list: Dheda K, Mirzayev F, Cirillo DM, Udwadia Z, Dooley KE, Chang KC, Omar SV, Reuter A, Perumal T, Horsburgh CR, Murray M, Lange C
published in: Nature reviews. Disease primers
information resource reference: Multidrug-resistant tuberculosis. Nat Rev Dis Primers. 2024 Mar 24; 10(1):22.
journal title abbreviation: Nat Rev Dis Primers
publication date: 2024-03-24T00:00:00
year: 2024
type: Academic Article
type: Article
type: Document
type: Information Resource

On the effect heterogeneity of established disease susceptibility loci for Alzheimer's disease across different genetic ancestries.
PubMed Identifier: 38563508
author list: Lee S, Hecker J, Hahn G, Mullin K, Lutz SM, Tanzi RE, Lange C, Prokopenko D
published in: Alzheimer's & dementia : the journal of the Alzheimer's Association
information resource reference: On the effect heterogeneity of established disease susceptibility loci for Alzheimer's disease across different genetic ancestries. Alzheimers Dement. 2024 05; 20(5):3397-3405.
journal title abbreviation: Alzheimers Dement
publication date: 2024-04-02T00:00:00
year: 2024
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 232557
type: Authorship
author rank in publication: 2
linked author: Lange, Christoph
linked information resource: Family-based designs in the age of large-scale gene-association studies.

Examining the Effect of Genes on Depression as Mediated by Smoking and Modified by Sex.
PubMed Identifier: 38790194
author list: Voorhies K, Hecker J, Lee S, Hahn G, Prokopenko D, McDonald ML, Wu AC, Wu A, Hokanson JE, Cho MH, Lange C, Hoth KF, Lutz SM
published in: Genes
information resource reference: Examining the Effect of Genes on Depression as Mediated by Smoking and Modified by Sex. Genes (Basel). 2024 04 27; 15(5).
journal title abbreviation: Genes (Basel)
publication date: 2024-04-27T00:00:00
year: 2024
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 279208
type: Authorship
author rank in publication: 1
linked author: Lange, Christoph
linked information resource: A family-based association test for repeatedly measured quantitative traits adjusting for unknown environmental and/or polygenic effects.

Authorship 1656159
type: Authorship
author rank in publication: 11
linked author: Lange, Christoph
linked information resource: Prediction of disease-free survival for precision medicine using cooperative learning on multi-omic data.

Prediction of disease-free survival for precision medicine using cooperative learning on multi-omic data.
PubMed Identifier: 38836403
author list: Hahn G, Prokopenko D, Hecker J, Lutz SM, Mullin K, Sejour L, Hide W, Vlachos I, DeSantis S, Tanzi RE, Lange C
published in: Briefings in bioinformatics
information resource reference: Prediction of disease-free survival for precision medicine using cooperative learning on multi-omic data. Brief Bioinform. 2024 May 23; 25(4).
journal title abbreviation: Brief Bioinform
publication date: 2024-05-23T00:00:00
year: 2024
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 337498
type: Authorship
author rank in publication: 21
linked author: Lange, Christoph
linked information resource: Accuracy of immunodiagnostic tests for active tuberculosis using single and combined results: a multicenter TBNET-Study.

Authorship 1665535
type: Authorship
author rank in publication: 8
linked author: Lange, Christoph
linked information resource: Polygenic hazard score models for the prediction of Alzheimer's free survival using the lasso for Cox's proportional hazards model.

Polygenic hazard score models for the prediction of Alzheimer's free survival using the lasso for Cox's proportional hazards model.
PubMed Identifier: 38982682
author list: Hahn G, Prokopenko D, Hecker J, Lutz SM, Mullin K, Tanzi RE, DeSantis S, Lange C
published in: Genetic epidemiology
information resource reference: Polygenic hazard score models for the prediction of Alzheimer's free survival using the lasso for Cox's proportional hazards model. Genet Epidemiol. 2025 Jan; 49(1):e22581.
journal title abbreviation: Genet Epidemiol
publication date: 2024-07-09T00:00:00
year: 2024
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 239573
type: Authorship
author rank in publication: 3
linked author: Lange, Christoph
linked information resource: Screening and replication using the same data set: testing strategies for family-based studies in which all probands are affected.

Authorship 1670120
type: Authorship
author rank in publication: 17
linked author: Lange, Christoph
linked information resource: Association of PHACTR1 with Coronary Artery Calcium Differs by Sex and Cigarette Smoking.

Association of PHACTR1 with Coronary Artery Calcium Differs by Sex and Cigarette Smoking.
PubMed Identifier: 39057616
author list: Voorhies K, Young K, Hsu FC, Palmer ND, McDonald MN, Lee S, Hahn G, Hecker J, Prokopenko D, Wu AC, Regan EA, DeMeo D, Kinney GL, Crapo JD, Cho MH, Silverman EK, Lange C, Budoff MJ, Hokanson JE, Lutz SM
published in: Journal of cardiovascular development and disease
information resource reference: Association of PHACTR1 with Coronary Artery Calcium Differs by Sex and Cigarette Smoking. J Cardiovasc Dev Dis. 2024 Jun 27; 11(7).
journal title abbreviation: J Cardiovasc Dev Dis
publication date: 2024-06-27T00:00:00
year: 2024
type: Academic Article
type: Article
type: Document
type: Information Resource

Target regimen profiles for tuberculosis treatment.
PubMed Identifier: 39070602
author list: Lienhardt C, Dooley KE, Nahid P, Wells C, Ryckman TS, Kendall EA, Davies G, Brigden G, Churchyard G, Cirillo DM, Di Meco E, Gopinath R, Mitnick C, Scott C, Amanullah F, Bansbach C, Boeree M, Campbell M, Conradie F, Crook A, Daley CL, Dheda K, Diacon A, Gebhard A, Hanna D, Heinrich N, Hesseling A, Holtzman D, Jachym M, Kim P, Lange C, McKenna L, Meintjes G, Ndjeka N, Nhung NV, Nyang'wa BT, Paton NI, Rao R, Rich M, Savic R, Schoeman I, Makokotlela BS, Spigelman M, Sun E, Svensson E, Tisile P, Varaine F, Vernon A, Diul MY, Kasaeva T, Zignol M, Gegia M, Mirzayev F, Schumacher SG
published in: Bulletin of the World Health Organization
information resource reference: Target regimen profiles for tuberculosis treatment. Bull World Health Organ. 2024 Aug 01; 102(8):600-607.
journal title abbreviation: Bull World Health Organ
publication date: 2024-05-28T00:00:00
year: 2024
type: Academic Article
type: Article
type: Document
type: Information Resource

Assistant Professor of Neurology
is primary position: true
position in department: Neurology
position in division: https://connects.catalyst.harvard.edu/Profiles/profile/1229413
sort order: 1
type: Position
HR job title: Assistant Professor of Neurology
position in organization: Massachusetts General Hospital

Authorship 437346
type: Authorship
author rank in publication: 2
linked author: Lange, Christoph
linked information resource: Genetic model testing and statistical power in population-based association studies of quantitative traits.

Rare autosomal copy number variations in early-onset familial Alzheimer's disease.
PubMed Identifier: 23752245
author list: Hooli BV, Kovacs-Vajna ZM, Mullin K, Blumenthal MA, Mattheisen M, Zhang C, Lange C, Mohapatra G, Bertram L, Tanzi RE
published in: Molecular psychiatry
information resource reference: Rare autosomal copy number variations in early-onset familial Alzheimer's disease. Mol Psychiatry. 2014 Jun; 19(6):676-81.
journal title abbreviation: Mol Psychiatry
publication date: 2013-06-11T00:00:00
year: 2013
type: Academic Article
type: Article
type: Document
type: Information Resource

Modernizing the family-based association testing (FBAT) approach and its software implementation in the FBAT-program
end date: 2025-08-31
principal investigator name: LANGE, CHRISTOPH
start date: 2024-09-25
type: Grant
sponsor award id: R56HG013314

Principal Investigator
type: Researcher Role
researcher role of: Lange, Christoph
contributes to: Modernizing the family-based association testing (FBAT) approach and its software implementation in the FBAT-program

Authorship 649962
type: Authorship
author rank in publication: 5
linked author: Lange, Christoph
linked information resource: A general semi-parametric approach to the analysis of genetic association studies in population-based designs.

Authorship 668125
type: Authorship
author rank in publication: 3
linked author: Lange, Christoph
linked information resource: On association analysis of rare variants under population substructure: an approach for the detection of subjects that can cause bias in the analysis--T opt: an outlier detection method.

On association analysis of rare variants under population substructure: an approach for the detection of subjects that can cause bias in the analysis--T opt: an outlier detection method.
PubMed Identifier: 23674291
author list: Qiao D, Mattheisen M, Lange C
published in: Genetic epidemiology
information resource reference: On association analysis of rare variants under population substructure: an approach for the detection of subjects that can cause bias in the analysis--T opt: an outlier detection method. Genet Epidemiol. 2013 Jul; 37(5):431-9.
journal title abbreviation: Genet Epidemiol
publication date: 2013-05-14T00:00:00
year: 2013
type: Academic Article
type: Article
type: Document
type: Information Resource

A general semi-parametric approach to the analysis of genetic association studies in population-based designs.
PubMed Identifier: 23448186
author list: Lutz S, Yip WK, Hokanson J, Laird N, Lange C
published in: BMC genetics
information resource reference: A general semi-parametric approach to the analysis of genetic association studies in population-based designs. BMC Genet. 2013 Feb 28; 14:13.
journal title abbreviation: BMC Genet
publication date: 2013-02-28T00:00:00
year: 2013
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1697211
type: Authorship
author rank in publication: 5
linked author: Lange, Christoph
linked information resource: Letter to the editor: critical evaluation of the reliability of DNA methylation probes on the illumina MethylationEPIC v1.0 BeadChip microarrays.

Letter to the editor: critical evaluation of the reliability of DNA methylation probes on the illumina MethylationEPIC v1.0 BeadChip microarrays.
PubMed Identifier: 39365898
author list: Hecker J, Weiss ST, Lasky-Su JA, DeMeo DL, Lange C
published in: Epigenetics
information resource reference: Letter to the editor: critical evaluation of the reliability of DNA methylation probes on the illumina MethylationEPIC v1.0 BeadChip microarrays. Epigenetics. 2024 Dec; 19(1):2411470.
journal title abbreviation: Epigenetics
publication date: 2024-10-04T00:00:00
year: 2024
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 201122
type: Authorship
author rank in publication: 8
linked author: Lange, Christoph
linked information resource: Association of SERPINE2 with asthma.

Assessing polyomic risk to predict Alzheimer's disease using a machine learning model.
PubMed Identifier: 39511865
author list: Ngai T, Willett J, Waqas M, Fishbein LH, Choi Y, Hahn G, Mullin K, Lange C, Hecker J, Tanzi RE, Prokopenko D
published in: Alzheimer's & dementia : the journal of the Alzheimer's Association
information resource reference: Assessing polyomic risk to predict Alzheimer's disease using a machine learning model. Alzheimers Dement. 2024 12; 20(12):8700-8714.
journal title abbreviation: Alzheimers Dement
publication date: 2024-11-07T00:00:00
year: 2024
type: Academic Article
type: Article
type: Document
type: Information Resource

Molecular hallmarks of excitatory and inhibitory neuronal resilience and resistance to Alzheimer's disease.
PubMed Identifier: 39868232
author list: Castanho I, Yeganeh PN, Boix CA, Morgan SL, Mathys H, Prokopenko D, White B, Soto LM, Pegoraro G, Shah S, Ploumakis A, Kalavros N, Bennett DA, Lange C, Kim DY, Bertram L, Tsai LH, Kellis M, Tanzi RE, Hide W
published in: bioRxiv : the preprint server for biology
information resource reference: Molecular hallmarks of excitatory and inhibitory neuronal resilience and resistance to Alzheimer's disease. bioRxiv. 2025 Jan 15.
journal title abbreviation: bioRxiv
publication date: 2025-01-15T00:00:00
year: 2025
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 217973
type: Authorship
author rank in publication: 11
linked author: Lange, Christoph
linked information resource: Variants in FAM13A are associated with chronic obstructive pulmonary disease.

Fish intake during pregnancy and the risk of child asthma and allergic rhinitis - longitudinal evidence from the Danish National Birth Cohort.
PubMed Identifier: 23473120
author list: Maslova E, Strøm M, Oken E, Campos H, Lange C, Gold D, Olsen SF
published in: The British journal of nutrition
information resource reference: Fish intake during pregnancy and the risk of child asthma and allergic rhinitis - longitudinal evidence from the Danish National Birth Cohort. Br J Nutr. 2013 Oct; 110(7):1313-25.
journal title abbreviation: Br J Nutr
publication date: 2013-03-08T00:00:00
year: 2013
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 680084
type: Authorship
author rank in publication: 4
linked author: Lange, Christoph
linked information resource: Principal components methods for narrow-sense heritability in the analysis of multidimensional longitudinal cognitive phenotypes.

Sex-specific association of a common variant of the XG gene with autism spectrum disorders.
PubMed Identifier: 24132906
author list: Chang SC, Pauls DL, Lange C, Sasanfar R, Santangelo SL
published in: American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics
information resource reference: Sex-specific association of a common variant of the XG gene with autism spectrum disorders. Am J Med Genet B Neuropsychiatr Genet. 2013 Oct; 162B(7):742-50.
journal title abbreviation: Am J Med Genet B Neuropsychiatr Genet
publication date: 2013-10-01T00:00:00
year: 2013
type: Academic Article
type: Article
type: Document
type: Information Resource

Principal components methods for narrow-sense heritability in the analysis of multidimensional longitudinal cognitive phenotypes.
PubMed Identifier: 23650207
author list: Fung WL, Naylor MG, Bennett DA, Lange C, Blacker D
published in: American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics
information resource reference: Principal components methods for narrow-sense heritability in the analysis of multidimensional longitudinal cognitive phenotypes. Am J Med Genet B Neuropsychiatr Genet. 2013 Oct; 162B(7):770-8.
journal title abbreviation: Am J Med Genet B Neuropsychiatr Genet
publication date: 2013-05-06T00:00:00
year: 2013
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 301386
type: Authorship
author rank in publication: 1
linked author: Lange, Christoph
linked information resource: On prediction of genetic values in marker-assisted selection.

Authorship 688843
type: Authorship
author rank in publication: 6
linked author: Lange, Christoph
linked information resource: Dendritic cell recruitment in response to skin antigen tests in HIV-1-infected individuals correlates with the level of T-cell infiltration.

Authorship 687514
type: Authorship
author rank in publication: 3
linked author: Lange, Christoph
linked information resource: Sex-specific association of a common variant of the XG gene with autism spectrum disorders.

Dendritic cell recruitment in response to skin antigen tests in HIV-1-infected individuals correlates with the level of T-cell infiltration.
PubMed Identifier: 23324660
author list: Liang F, Bond E, Sandgren KJ, Smed-Sörensen A, Rangaka MX, Lange C, Koup RA, McComsey GA, Lederman MM, Wilkinson RJ, Andersson J, Loré K
published in: AIDS (London, England)
information resource reference: Dendritic cell recruitment in response to skin antigen tests in HIV-1-infected individuals correlates with the level of T-cell infiltration. AIDS. 2013 Apr 24; 27(7):1071-80.
journal title abbreviation: AIDS
publication date: 2013-04-24T00:00:00
year: 2013
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1740603
type: Authorship
author rank in publication: 10
linked author: Lange, Christoph
linked information resource: On the analysis of metabolite quantitative trait loci: Impact of different data transformations and study designs.

Authorship 1744792
type: Authorship
author rank in publication: 17
linked author: Lange, Christoph
linked information resource: Associations of APOE variants with sphingomyelin and cholesterol metabolites across the life-course in diverse populations.

On the analysis of metabolite quantitative trait loci: Impact of different data transformations and study designs.
PubMed Identifier: 40215300
author list: Lee S, Kelly RS, Mendez KM, Prokopenko D, Hahn G, Lutz SM, Celedón JC, Clish CB, Weiss ST, Lange C, Lasky-Su JA, Hecker J
published in: Science advances
information resource reference: On the analysis of metabolite quantitative trait loci: Impact of different data transformations and study designs. Sci Adv. 2025 Apr 11; 11(15):eadp4532.
journal title abbreviation: Sci Adv
publication date: 2025-04-11T00:00:00
year: 2025
type: Academic Article
type: Article
type: Document
type: Information Resource

Associations of APOE variants with sphingomyelin and cholesterol metabolites across the life-course in diverse populations.
PubMed Identifier: 40335834
author list: Lee S, Kelly RS, Chen Y, Waqas M, Mendez KM, Hecker J, Hahn G, Lutz SM, Celedón JC, Clish CB, Litonjua AA, Chen Q, McGeachie M, Choi Y, Weiss ST, Tanzi RE, Lange C, Prokopenko D, Lasky-Su JA
published in: Metabolomics : Official journal of the Metabolomic Society
information resource reference: Associations of APOE variants with sphingomyelin and cholesterol metabolites across the life-course in diverse populations. Metabolomics. 2025 May 07; 21(3):64.
journal title abbreviation: Metabolomics
publication date: 2025-05-07T00:00:00
year: 2025
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 170530
type: Authorship
author rank in publication: 1
linked author: Lange, Christoph
linked information resource: Using the noninformative families in family-based association tests: a powerful new testing strategy.

Authorship 698699
type: Authorship
author rank in publication: 3
linked author: Lange, Christoph
linked information resource: Testing for direct genetic effects using a screening step in family-based association studies.

Authorship 698843
type: Authorship
author rank in publication: 15
linked author: Lange, Christoph
linked information resource: Efficient strategy for detecting gene × gene joint action and its application in schizophrenia.

Testing for direct genetic effects using a screening step in family-based association studies.
PubMed Identifier: 24312120
author list: Lutz SM, Vansteelandt S, Lange C
published in: Frontiers in genetics
information resource reference: Testing for direct genetic effects using a screening step in family-based association studies. Front Genet. 2013; 4:243.
journal title abbreviation: Front Genet
publication date: 2013-11-21T00:00:00
year: 2013
type: Academic Article
type: Article
type: Document
type: Information Resource

Efficient strategy for detecting gene × gene joint action and its application in schizophrenia.
PubMed Identifier: 24272960
author list: Won S, Kwon MS, Mattheisen M, Park S, Park C, Kihara D, Cichon S, Ophoff R, Nöthen MM, Rietschel M, Baur M, Uitterlinden AG, Hofmann A, Lange C
published in: Genetic epidemiology
information resource reference: Efficient strategy for detecting gene × gene joint action and its application in schizophrenia. Genet Epidemiol. 2014 Jan; 38(1):60-71.
journal title abbreviation: Genet Epidemiol
publication date: 2013-11-23T00:00:00
year: 2013
type: Academic Article
type: Article
type: Document
type: Information Resource

A genome-wide association study of bronchodilator response in asthmatics.
PubMed Identifier: 23508266
author list: Duan QL, Lasky-Su J, Himes BE, Qiu W, Litonjua AA, Damask A, Lazarus R, Klanderman B, Irvin CG, Peters SP, Hanrahan JP, Lima JJ, Martinez FD, Mauger D, Chinchilli VM, Soto-Quiros M, Avila L, Celedón JC, Lange C, Weiss ST, Tantisira KG
published in: The pharmacogenomics journal
information resource reference: A genome-wide association study of bronchodilator response in asthmatics. Pharmacogenomics J. 2014 Feb; 14(1):41-7.
journal title abbreviation: Pharmacogenomics J
publication date: 2013-03-19T00:00:00
year: 2013
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 703927
type: Authorship
author rank in publication: 7
linked author: Lange, Christoph
linked information resource: On the simultaneous association analysis of large genomic regions: a massive multi-locus association test.

Authorship 703992
type: Authorship
author rank in publication: 6
linked author: Lange, Christoph
linked information resource: Properties of permutation-based gene tests and controlling type 1 error using a summary statistic based gene test.

On the simultaneous association analysis of large genomic regions: a massive multi-locus association test.
PubMed Identifier: 24262215
author list: Qiao D, Cho MH, Fier H, Bakke PS, Gulsvik A, Silverman EK, Lange C
published in: Bioinformatics (Oxford, England)
information resource reference: On the simultaneous association analysis of large genomic regions: a massive multi-locus association test. Bioinformatics. 2014 Jan 15; 30(2):157-64.
journal title abbreviation: Bioinformatics
publication date: 2013-11-20T00:00:00
year: 2013
type: Academic Article
type: Article
type: Document
type: Information Resource

Properties of permutation-based gene tests and controlling type 1 error using a summary statistic based gene test.
PubMed Identifier: 24199751
author list: Swanson DM, Blacker D, Alchawa T, Ludwig KU, Mangold E, Lange C
published in: BMC genetics
information resource reference: Properties of permutation-based gene tests and controlling type 1 error using a summary statistic based gene test. BMC Genet. 2013 Nov 07; 14:108.
journal title abbreviation: BMC Genet
publication date: 2013-11-07T00:00:00
year: 2013
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 390458
type: Authorship
author rank in publication: 2
linked author: Lange, Christoph
linked information resource: Parsing the effects of individual SNPs in candidate genes with family data.

Authorship 207437
type: Authorship
author rank in publication: 11
linked author: Lange, Christoph
linked information resource: Testing and estimating gene-environment interactions in family-based association studies.

Risk loci for chronic obstructive pulmonary disease: a genome-wide association study and meta-analysis.
PubMed Identifier: 24621683
author list: Cho MH, McDonald ML, Zhou X, Mattheisen M, Castaldi PJ, Hersh CP, Demeo DL, Sylvia JS, Ziniti J, Laird NM, Lange C, Litonjua AA, Sparrow D, Casaburi R, Barr RG, Regan EA, Make BJ, Hokanson JE, Lutz S, Dudenkov TM, Farzadegan H, Hetmanski JB, Tal-Singer R, Lomas DA, Bakke P, Gulsvik A, Crapo JD, Silverman EK, Beaty TH
published in: The Lancet. Respiratory medicine
information resource reference: Risk loci for chronic obstructive pulmonary disease: a genome-wide association study and meta-analysis. Lancet Respir Med. 2014 Mar; 2(3):214-25.
journal title abbreviation: Lancet Respir Med
publication date: 2014-02-07T00:00:00
year: 2014
type: Academic Article
type: Article
type: Document
type: Information Resource

Quantitative computed tomography measures of pectoralis muscle area and disease severity in chronic obstructive pulmonary disease. A cross-sectional study.
PubMed Identifier: 24558953
author list: McDonald ML, Diaz AA, Ross JC, San Jose Estepar R, Zhou L, Regan EA, Eckbo E, Muralidhar N, Come CE, Cho MH, Hersh CP, Lange C, Wouters E, Casaburi RH, Coxson HO, Macnee W, Rennard SI, Lomas DA, Agusti A, Celli BR, Black-Shinn JL, Kinney GL, Lutz SM, Hokanson JE, Silverman EK, Washko GR
published in: Annals of the American Thoracic Society
information resource reference: Quantitative computed tomography measures of pectoralis muscle area and disease severity in chronic obstructive pulmonary disease. A cross-sectional study. Ann Am Thorac Soc. 2014 Mar; 11(3):326-34.
journal title abbreviation: Ann Am Thorac Soc
publication date: 2014-03-01T00:00:00
year: 2014
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 470167
type: Authorship
author rank in publication: 1
linked author: Lange, Christoph
linked information resource: A new powerful non-parametric two-stage approach for testing multiple phenotypes in family-based association studies.

Authorship 472500
type: Authorship
author rank in publication: 1
linked author: Lange, Christoph
linked information resource: Proliferation responses to HIVp24 during antiretroviral therapy do not reflect improved immune phenotype or function.

Authorship 326200
type: Authorship
author rank in publication: 2
linked author: Lange, Christoph
linked information resource: S100A7/psoriasin expression in the human lung: unchanged in patients with COPD, but upregulated upon positive S. aureus detection.

Authorship 330819
type: Authorship
author rank in publication: 3
linked author: Lange, Christoph
linked information resource: The SERPINE2 gene is associated with chronic obstructive pulmonary disease.

Authorship 724204
type: Authorship
author rank in publication: 3
linked author: Lange, Christoph
linked information resource: On rare-variant analysis in population-based designs: decomposing the likelihood to two informative components.

Authorship 718827
type: Authorship
author rank in publication: 5
linked author: Lange, Christoph
linked information resource: Fish intake during pregnancy and the risk of child asthma and allergic rhinitis - longitudinal evidence from the Danish National Birth Cohort.

Authorship 715063
type: Authorship
author rank in publication: 2
linked author: Lange, Christoph
linked information resource: Family-based designs.

Authorship 720406
type: Authorship
author rank in publication: 12
linked author: Lange, Christoph
linked information resource: Quantitative computed tomography measures of pectoralis muscle area and disease severity in chronic obstructive pulmonary disease. A cross-sectional study.

Authorship 723299
type: Authorship
author rank in publication: 11
linked author: Lange, Christoph
linked information resource: Risk loci for chronic obstructive pulmonary disease: a genome-wide association study and meta-analysis.

Family-based designs.
PubMed Identifier: 22997867
author list: Amos CI, Lange C
published in: IARC scientific publications
information resource reference: Family-based designs. IARC Sci Publ. 2011; (163):261-80.
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On rare-variant analysis in population-based designs: decomposing the likelihood to two informative components.
PubMed Identifier: 24434864
author list: Won S, Kim Y, Lange C
published in: Human heredity
information resource reference: On rare-variant analysis in population-based designs: decomposing the likelihood to two informative components. Hum Hered. 2013; 76(2):76-85.
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Authorship 224314
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author rank in publication: 2
linked author: Lange, Christoph
linked information resource: Statistical challenges for genome-wide association studies of suicidality using family data.

Authorship 171182
type: Authorship
author rank in publication: 3
linked author: Lange, Christoph
linked information resource: Single-nucleotide polymorphism rs498055 on chromosome 10q24 is not associated with Alzheimer disease in two independent family samples.

Authorship 340512
type: Authorship
author rank in publication: 9
linked author: Lange, Christoph
linked information resource: On the analysis of genome-wide association studies in family-based designs: a universal, robust analysis approach and an application to four genome-wide association studies.

Common genetic variants associated with resting oxygenation in chronic obstructive pulmonary disease.
PubMed Identifier: 24825563
author list: McDonald ML, Cho MH, Sørheim IC, Lutz SM, Castaldi PJ, Lomas DA, Coxson HO, Edwards LD, MacNee W, Vestbo J, Yates JC, Agusti A, Calverley PM, Celli B, Crim C, Rennard SI, Wouters EF, Bakke P, Tal-Singer R, Miller BE, Gulsvik A, Casaburi R, Wells JM, Regan EA, Make BJ, Hokanson JE, Lange C, Crapo JD, Beaty TH, Silverman EK, Hersh CP
published in: American journal of respiratory cell and molecular biology
information resource reference: Common genetic variants associated with resting oxygenation in chronic obstructive pulmonary disease. Am J Respir Cell Mol Biol. 2014 Nov; 51(5):678-87.
journal title abbreviation: Am J Respir Cell Mol Biol
publication date: 2014-11-01T00:00:00
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type: Academic Article
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Gilbert S. Omenn, MD ’65, PhD Associate Professor of Biomedical Informatics
is primary position: true
position in department: Biomedical Informatics
position in division: https://connects.catalyst.harvard.edu/Profiles/profile/1229413
sort order: 1
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HR job title: Gilbert S. Omenn, MD ’65, PhD Associate Professor of Biomedical Informatics
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Authorship 732274
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author rank in publication: 16
linked author: Lange, Christoph
linked information resource: Integrated pathway-based approach identifies association between genomic regions at CTCF and CACNB2 and schizophrenia.

Integrated pathway-based approach identifies association between genomic regions at CTCF and CACNB2 and schizophrenia.
PubMed Identifier: 24901509
author list: Juraeva D, Haenisch B, Zapatka M, Frank J, Witt SH, Mühleisen TW, Treutlein J, Strohmaier J, Meier S, Degenhardt F, Giegling I, Ripke S, Leber M, Lange C, Schulze TG, Mössner R, Nenadic I, Sauer H, Rujescu D, Maier W, Børglum A, Ophoff R, Cichon S, Nöthen MM, Rietschel M, Mattheisen M, Brors B
published in: PLoS genetics
information resource reference: Integrated pathway-based approach identifies association between genomic regions at CTCF and CACNB2 and schizophrenia. PLoS Genet. 2014 Jun; 10(6):e1004345.
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Authorship 1768677
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author rank in publication: 31
linked author: Lange, Christoph
linked information resource: Target regimen profiles for tuberculosis treatment.

Authorship 1768968
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author rank in publication: 4
linked author: Lange, Christoph
linked information resource: The Role of Sex in Genetic Association Studies of Depression.

Authorship 1769041
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author rank in publication: 11
linked author: Lange, Christoph
linked information resource: Examining the Effect of Genes on Depression as Mediated by Smoking and Modified by Sex.

Authorship 1769556
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author rank in publication: 26
linked author: Lange, Christoph
linked information resource: A standardised method for interpreting the association between mutations and phenotypic drug resistance in Mycobacterium tuberculosis.

Authorship 1769886
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author rank in publication: 5
linked author: Lange, Christoph
linked information resource: Optimizing DNA Extraction from Pediatric Stool for Diagnosis of Tuberculosis and Use in Next-Generation Sequencing Applications.

Authorship 1773845
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author rank in publication: 37
linked author: Lange, Christoph
linked information resource: Cross-reactive immunity against the SARS-CoV-2 Omicron variant is low in pediatric patients with prior COVID-19 or MIS-C.

Authorship 1774302
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author rank in publication: 9
linked author: Lange, Christoph
linked information resource: Whole-genome sequencing reveals new Alzheimer's disease-associated rare variants in loci related to synaptic function and neuronal development.

Authorship 1776299
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author rank in publication: 5
linked author: Lange, Christoph
linked information resource: Effect of population stratification on SNP-by-environment interaction.

Authorship 1767179
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author rank in publication: 14
linked author: Lange, Christoph
linked information resource: Molecular hallmarks of excitatory and inhibitory neuronal resilience and resistance to Alzheimer's disease.

Authorship 1767839
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author rank in publication: 8
linked author: Lange, Christoph
linked information resource: On the effect heterogeneity of established disease susceptibility loci for Alzheimer's disease across different genetic ancestries.

Authorship 1767967
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author rank in publication: 12
linked author: Lange, Christoph
linked information resource: Multidrug-resistant tuberculosis.

Authorship 1772968
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author rank in publication: 8
linked author: Lange, Christoph
linked information resource: Assessing polyomic risk to predict Alzheimer's disease using a machine learning model.

Authorship 1777497
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author rank in publication: 3
linked author: Lange, Christoph
linked information resource: Reply to Neupane et al.: Replication study of AD-associated rare variants.

Authorship 1781586
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author rank in publication: 10
linked author: Lange, Christoph
linked information resource: Whole-genome sequencing reveals new Alzheimer's disease-associated rare variants in loci related to synaptic function and neuronal development.

Authorship 1785257
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author rank in publication: 37
linked author: Lange, Christoph
linked information resource: Author Correction: Cross-reactive immunity against the SARS-CoV-2 Omicron variant is low in pediatric patients with prior COVID-19 or MIS-C.

Authorship 736965
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author rank in publication: 2
linked author: Lange, Christoph
linked information resource: Progress in tuberculosis vaccine development and host-directed therapies--a state of the art review.

Progress in tuberculosis vaccine development and host-directed therapies--a state of the art review.
PubMed Identifier: 24717627
author list: Kaufmann SH, Lange C, Rao M, Balaji KN, Lotze M, Schito M, Zumla AI, Maeurer M
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information resource reference: Progress in tuberculosis vaccine development and host-directed therapies--a state of the art review. Lancet Respir Med. 2014 Apr; 2(4):301-20.
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Authorship 1786811
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linked author: Lange, Christoph
linked information resource: Childhood BCG vaccination does not influence control of Mycobacterium tuberculosis growth by human bronchoalveolar lavage cells.

Authorship 1786981
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author rank in publication: 2
linked author: Lange, Christoph
linked information resource: Editorial Commentary: 1, 2, 3 (Years)??…??and You're Out: The End of a 123-year Historic Era.

Authorship 1787344
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author rank in publication: 13
linked author: Lange, Christoph
linked information resource: Tuberculosis Treatment Outcomes in Europe: Based on Treatment Completion, Not Cure.

Authorship 1787745
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author rank in publication: 8
linked author: Lange, Christoph
linked information resource: Treatment of Chronic Pulmonary Aspergillosis: Current Standards and Future Perspectives.

Authorship 1787833
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author rank in publication: 16
linked author: Lange, Christoph
linked information resource: Intensive care unit patients with lower respiratory tract nosocomial infections: the ENIRRIs project.

Authorship 1788801
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linked author: Lange, Christoph
linked information resource: A comprehensive quality assessment framework for scientific events.

Authorship 1788458
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linked author: Lange, Christoph
linked information resource: Treatment of nontuberculous mycobacterial pulmonary disease: an official ATS/ERS/ESCMID/IDSA clinical practice guideline.

Authorship 1789565
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linked author: Lange, Christoph
linked information resource: 100 years of Mycobacterium bovis bacille Calmette-Guérin.

Authorship 1789056
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author rank in publication: 13
linked author: Lange, Christoph
linked information resource: Long-term multidrug- and rifampicin-resistant tuberculosis treatment outcome by new WHO definitions in Germany.

Authorship 1789841
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linked author: Lange, Christoph
linked information resource: Preventive chemotherapy for contacts of MDR-TB: is the proof in the pudding?

Authorship 1790360
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author rank in publication: 3
linked author: Lange, Christoph
linked information resource: False-negative interferon-? release assay results in active tuberculosis: a TBNET study.

Authorship 1789433
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author rank in publication: 7
linked author: Lange, Christoph
linked information resource: Mycobacterial infections in adults with haematological malignancies and haematopoietic stem cell transplants: guidelines from the 8th European Conference on Infections in Leukaemia.

Authorship 1789972
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author rank in publication: 11
linked author: Lange, Christoph
linked information resource: Tuberculosis endotypes to guide stratified host-directed therapy.

Authorship 1791160
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author rank in publication: 11
linked author: Lange, Christoph
linked information resource: Aspergillus-specific IgG antibodies for diagnosing chronic pulmonary aspergillosis compared to the reference standard.

Authorship 1790238
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author rank in publication: 8
linked author: Lange, Christoph
linked information resource: High risk of drug-resistant tuberculosis in IGRA-negative contacts: should preventive treatment be considered?

Authorship 1790793
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author rank in publication: 15
linked author: Lange, Christoph
linked information resource: Rapid tuberculosis diagnosis from respiratory or blood samples by a low cost, portable lab-in-tube assay.

Authorship 1791625
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author rank in publication: 55
linked author: Lange, Christoph
linked information resource: Tuberculosis incidence in foreign-born people residing in European countries in 2020.

Authorship 1794623
type: Authorship
author rank in publication: 9
linked author: Lange, Christoph
linked information resource: Noninvasive diagnosis of pulmonary tuberculosis using face mask sampling: a prospective study in adults.

Authorship 1794939
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author rank in publication: 23
linked author: Lange, Christoph
linked information resource: Host- and pathogen-related determinants of pulmonary versus extrapulmonary tuberculosis.

Authorship 1795010
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author rank in publication: 5
linked author: Lange, Christoph
linked information resource: Management of adverse events in TB care and active TB drug safety monitoring.

Authorship 1795773
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author rank in publication: 15
linked author: Lange, Christoph
linked information resource: Whispers in the Wind: Face Mask Sampling for Mycobacterium tuberculosis Detection in Children With Pulmonary Tuberculosis.

Authorship 1795984
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author rank in publication: 6
linked author: Lange, Christoph
linked information resource: Thermostability of IFN-? and IP-10 release assays for latent infection with Mycobacterium tuberculosis: A TBnet study.

Authorship 1795578
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author rank in publication: 11
linked author: Lange, Christoph
linked information resource: Management of nontuberculous mycobacterial Pulmonary disease refractory to guideline-based therapy: A systematic review.

Authorship 1797400
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author rank in publication: 8
linked author: Lange, Christoph
linked information resource: QT prolongation and cardiac toxicity of new tuberculosis drugs in Europe: a Tuberculosis Network European Trialsgroup (TBnet) study.

Authorship 1796948
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author rank in publication: 6
linked author: Lange, Christoph
linked information resource: Chronic Cough and Severe Weight Loss in a 55-Year-Old Previously Healthy Man.

Authorship 1798263
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author rank in publication: 15
linked author: Lange, Christoph
linked information resource: What Is Resistance? Impact of Phenotypic versus Molecular Drug Resistance Testing on Therapy for Multi- and Extensively Drug-Resistant Tuberculosis.

Authorship 1797872
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author rank in publication: 4
linked author: Lange, Christoph
linked information resource: Diagnosis and Management of Systemic Endemic Mycoses Causing Pulmonary Disease.

Authorship 1799064
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author rank in publication: 5
linked author: Lange, Christoph
linked information resource: Poor adherence to management guidelines in nontuberculous mycobacterial pulmonary diseases.

Authorship 1799933
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author rank in publication: 1
linked author: Lange, Christoph
linked information resource: Drug-resistant tuberculosis: An update on disease burden, diagnosis and treatment.

Authorship 1798755
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author rank in publication: 15
linked author: Lange, Christoph
linked information resource: Reply to Dookie et al., "Whole-Genome Sequencing To Guide the Selection of Treatment for Drug-Resistant Tuberculosis".

Authorship 1800464
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author rank in publication: 3
linked author: Lange, Christoph
linked information resource: [Diagnostics and treatment of tuberculosis under immunotherapy for multiple sclerosis : Current status and recommendations in Germany].

Authorship 1799880
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author rank in publication: 5
linked author: Lange, Christoph
linked information resource: Bedaquiline-based treatment regimen for multidrug-resistant tuberculosis.

Authorship 1800512
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author rank in publication: 16
linked author: Lange, Christoph
linked information resource: Standardised shorter regimens versus individualised longer regimens for rifampin- or multidrug-resistant tuberculosis.

Authorship 1800564
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author rank in publication: 16
linked author: Lange, Christoph
linked information resource: Drug-associated adverse events in the treatment of multidrug-resistant tuberculosis: an individual patient data meta-analysis.

Authorship 1801566
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author rank in publication: 13
linked author: Lange, Christoph
linked information resource: Burden and Characteristics of the Comorbidity Tuberculosis-Diabetes in Europe: TBnet Prevalence Survey and Case-Control Study.

Authorship 1801779
type: Authorship
author rank in publication: 40
linked author: Lange, Christoph
linked information resource: Longitudinal Multi-omics Analyses Identify Responses of Megakaryocytes, Erythroid Cells, and Plasmablasts as Hallmarks of Severe COVID-19.

Authorship 1801783
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linked author: Lange, Christoph
linked information resource: Treatment of Nontuberculous Mycobacterial Pulmonary Disease: An Official ATS/ERS/ESCMID/IDSA Clinical Practice Guideline.

Authorship 1802350
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linked author: Lange, Christoph
linked information resource: Tuberculosis prevention in children: a prospective community-based study in South Africa.

Authorship 1802606
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linked author: Lange, Christoph
linked information resource: Challenging the management of drug-resistant tuberculosis - Authors' reply.

Authorship 1802677
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author rank in publication: 18
linked author: Lange, Christoph
linked information resource: Discovery and validation of a personalized risk predictor for incident tuberculosis in low transmission settings.

Authorship 1802854
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author rank in publication: 15
linked author: Lange, Christoph
linked information resource: Evidence-based Definition for Extensively Drug-Resistant Tuberculosis.

Authorship 1802072
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author rank in publication: 6
linked author: Lange, Christoph
linked information resource: Changes in treatment for multidrug-resistant tuberculosis according to national income.

Authorship 1802954
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author rank in publication: 32
linked author: Lange, Christoph
linked information resource: Prediction of anti-tuberculosis treatment duration based on a 22-gene transcriptomic model.

Authorship 1803001
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author rank in publication: 3
linked author: Lange, Christoph
linked information resource: Treatment outcomes of MDR-TB and HIV co-infection in Europe.

Authorship 1802529
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linked author: Lange, Christoph
linked information resource: Management of drug-resistant tuberculosis.

Authorship 1803492
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author rank in publication: 1
linked author: Lange, Christoph
linked information resource: Perspective for Precision Medicine for Tuberculosis.

Authorship 1802908
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author rank in publication: 1
linked author: Lange, Christoph
linked information resource: Treatments of Multidrug-Resistant Tuberculosis: Light at the End of the Tunnel.

Authorship 1803262
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author rank in publication: 18
linked author: Lange, Christoph
linked information resource: Design of Multidrug-Resistant Tuberculosis Treatment Regimens Based on DNA Sequencing.

Authorship 1804422
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author rank in publication: 4
linked author: Lange, Christoph
linked information resource: Pathogen-free diagnosis of tuberculosis.

Authorship 1804667
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linked author: Lange, Christoph
linked information resource: Emergence of bedaquiline resistance in a high tuberculosis burden country.

Authorship 1804803
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author rank in publication: 10
linked author: Lange, Christoph
linked information resource: Bedaquiline: what might the future hold?

Authorship 1804454
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author rank in publication: 15
linked author: Lange, Christoph
linked information resource: Rifapentine access in Europe: growing concerns over key tuberculosis treatment component.

Authorship 1805271
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linked author: Lange, Christoph
linked information resource: War in Ukraine: an immense threat to the fight against tuberculosis.

Authorship 1804942
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linked author: Lange, Christoph
linked information resource: Rapid molecular diagnostics of tuberculosis resistance by targeted stool sequencing.

Authorship 1804731
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author rank in publication: 17
linked author: Lange, Christoph
linked information resource: WNT6/ACC2-induced storage of triacylglycerols in macrophages is exploited by Mycobacterium tuberculosis.

Authorship 1805391
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author rank in publication: 19
linked author: Lange, Christoph
linked information resource: A successful UN High-Level Meeting on antimicrobial resistance must build on the 2023 UN High-Level Meeting on tuberculosis.

Authorship 1807104
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author rank in publication: 1
linked author: Lange, Christoph
linked information resource: Revisiting diagnostics: high priority tuberculosis diagnostic tests that fill an unmet need: what we need and what we do not need.

Authorship 1807420
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author rank in publication: 1
linked author: Lange, Christoph
linked information resource: Consensus management recommendations for less common non-tuberculous mycobacterial pulmonary diseases.

Authorship 1806627
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author rank in publication: 2
linked author: Lange, Christoph
linked information resource: Perspectives for systems biology in the management of tuberculosis.

Authorship 1806631
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linked author: Lange, Christoph
linked information resource: Case Report: Hemophagocytic Lymphohistiocytosis and Non-Tuberculous Mycobacteriosis Caused by a Novel GATA2 Variant.

Authorship 1807433
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linked author: Lange, Christoph
linked information resource: Global treatment outcomes of extensively drug-resistant tuberculosis in adults: A systematic review and meta-analysis.

Authorship 1807110
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author rank in publication: 11
linked author: Lange, Christoph
linked information resource: The molecular bacterial load assay predicts treatment responses in patients with pre-XDR/XDR-tuberculosis more accurately than GeneXpert Ultra MTB/Rif.

Authorship 1808134
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author rank in publication: 7
linked author: Lange, Christoph
linked information resource: Seroprevalence of Aspergillus-Specific IgG Antibody among Mozambican Tuberculosis Patients.

Authorship 1807455
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author rank in publication: 1
linked author: Lange, Christoph
linked information resource: A Year in Review on Tuberculosis and Non-tuberculous Mycobacteria Disease: A 2025 Update for Clinicians and Scientists.

Authorship 1808728
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author rank in publication: 16
linked author: Lange, Christoph
linked information resource: Performance of stool Xpert MTB/RIF Ultra for detection of Mycobacterium tuberculosis among adults living with HIV: a multicentre, prospective diagnostic study.

Authorship 1810383
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author rank in publication: 22
linked author: Lange, Christoph
linked information resource: Treatment outcome definitions in chronic pulmonary aspergillosis: a CPAnet consensus statement.

Authorship 1810214
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linked author: Lange, Christoph
linked information resource: A novel method for detecting Lipoarabinomannan in urine with the promise of meeting the WHO target product profile for the diagnosis of tuberculosis.

Authorship 1811586
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linked author: Lange, Christoph
linked information resource: Long-term treatment outcomes in patients with multidrug-resistant tuberculosis.

Authorship 1812953
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linked author: Lange, Christoph
linked information resource: Estimating the Accuracy and Additionality of TB-LAM to Diagnose TB in Children Without HIV (AccuLAM).

Authorship 1813724
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linked author: Lange, Christoph
linked information resource: A stool based qPCR for the diagnosis of TB in children and people living with HIV in Uganda, Eswatini and Mozambique (Stool4TB): a protocol for a multicenter diagnostic evaluation.

Authorship 1814685
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linked author: Lange, Christoph
linked information resource: Enhancing tuberculosis care in lower and middle-income countries through digital adherence technologies.

Authorship 1815423
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linked author: Lange, Christoph
linked information resource: A Single-Run HPLC-MS Multiplex Assay for Therapeutic Drug Monitoring of Relevant First- and Second-Line Antibiotics in the Treatment of Drug-Resistant Tuberculosis.

Authorship 1815518
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author rank in publication: 9
linked author: Lange, Christoph
linked information resource: Factors associated with new onset of depression and anxiety symptoms differ by sex in the COPDGene study.

Authorship 1815132
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linked author: Lange, Christoph
linked information resource: Emerging bedaquiline-resistant tuberculosis.

Authorship 1816448
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author rank in publication: 9
linked author: Lange, Christoph
linked information resource: Chronic Pulmonary Aspergillosis as a Considerable Complication in Post-Tuberculosis Lung Disease.

Authorship 1815739
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linked author: Lange, Christoph
linked information resource: Linezolid for the treatment of drug-resistant tuberculosis.

Authorship 1817253
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author rank in publication: 11
linked author: Lange, Christoph
linked information resource: A first-in-class leucyl-tRNA synthetase inhibitor, ganfeborole, for rifampicin-susceptible tuberculosis: a phase 2a open-label, randomized trial.

Authorship 1816378
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linked author: Lange, Christoph
linked information resource: Corrigendum to "Candidate anti-tuberculosis medicines and regimens under clinical evaluation" [Clin Microbiol Infect 30(9) (2024) 1131-1138].

Authorship 1817686
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linked author: Lange, Christoph
linked information resource: At the crossroads of infection and malignancy: the challenge of tuberculosis in migrating populations - Case Report and Epidemiologic Analysis.

Authorship 1817924
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author rank in publication: 22
linked author: Lange, Christoph
linked information resource: Performance of a stool-based quantitative PCR assay for the diagnosis of tuberculosis in adolescents and adults: a multinational, prospective diagnostic accuracy study.

Authorship 1816920
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author rank in publication: 6
linked author: Lange, Christoph
linked information resource: Safety of high dose bedaquiline treatment in patients with extensively drug-resistant tuberculosis.

Authorship 1816921
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author rank in publication: 11
linked author: Lange, Christoph
linked information resource: Consensus on the management of refractory nontuberculous mycobacterial pulmonary disease.

Authorship 1817396
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author rank in publication: 17
linked author: Lange, Christoph
linked information resource: Activin A levels are raised during human tuberculosis and blockade of the activin signaling axis influences murine responses to M. tuberculosis infection.

Authorship 1817552
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author rank in publication: 36
linked author: Lange, Christoph
linked information resource: Tuberculosis incidence in solid organ transplant recipients in Europe: A multicenter TBnet cohort study.

Authorship 1817736
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linked author: Lange, Christoph
linked information resource: A multinational Delphi consensus on tuberculosis screening of migrants in Europe.

Authorship 1819377
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author rank in publication: 20
linked author: Lange, Christoph
linked information resource: Increased protease-activated receptor 1 autoantibodies are associated with severe COVID-19.

Authorship 1819441
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linked author: Lange, Christoph
linked information resource: A Transcriptomic Biomarker Predicting Linezolid-Associated Neuropathy During Treatment of Drug-Resistant Tuberculosis.

Authorship 1819966
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linked author: Lange, Christoph
linked information resource: Candidate anti-tuberculosis medicines and regimens under clinical evaluation.

Authorship 1820455
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author rank in publication: 28
linked author: Lange, Christoph
linked information resource: The TB27 Transcriptomic Model for Predicting Mycobacterium tuberculosis Culture Conversion.

Authorship 1820664
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linked author: Lange, Christoph
linked information resource: Patients at risk of nontuberculous mycobacterial pulmonary disease who need testing evaluated using a modified Delphi process by European experts.

Authorship 1821248
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linked author: Lange, Christoph
linked information resource: The importance of getting the dose right in the treatment of tuberculosis.

Authorship 1821516
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linked author: Lange, Christoph
linked information resource: https://connects.catalyst.harvard.edu/Profiles/profile/323011892

Authorship 1820359
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linked author: Lange, Christoph
linked information resource: Rapid Diagnosis of Recurrent Paucibacillary Tuberculosis.

Authorship 1820595
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linked author: Lange, Christoph
linked information resource: Alveolar macrophages from persons living with HIV show impaired epigenetic response to Mycobacterium tuberculosis.

Authorship 1820831
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linked author: Lange, Christoph
linked information resource: Implementing molecular tuberculosis diagnostic methods in limited-resource and high-burden countries.

Authorship 1821342
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linked author: Lange, Christoph
linked information resource: Gene expression signatures identify biologically and clinically distinct tuberculosis endotypes.

Authorship 1821622
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linked author: Lange, Christoph
linked information resource: Correction: Rapid molecular diagnostics of tuberculosis resistance by targeted stool sequencing.

Authorship 1821870
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linked author: Lange, Christoph
linked information resource: Rapid Diagnostic Sequencing of Stool DNA Using Targeted Nanopore Sequencing in Patients With a Pulmonary Tuberculosis Diagnosis.

Authorship 1820699
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author rank in publication: 25
linked author: Lange, Christoph
linked information resource: Pretomanid-resistant tuberculosis.

Authorship 1820713
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linked author: Lange, Christoph
linked information resource: Towards shorter, safer, flexible, and more effective treatment regimens for drug-resistant tuberculosis.

Authorship 1822221
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author rank in publication: 17
linked author: Lange, Christoph
linked information resource: Performance of a Novel Stool Quantitative Polymerase Chain Reaction Assay for Pediatric Tuberculosis Detection in Sub-Saharan Africa.

Authorship 1822787
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author rank in publication: 12
linked author: Lange, Christoph
linked information resource: Uncovering Ethnicity-Specific Recessive Loci for Alzheimer's Disease in 89 Dominican Families Using Family-Based WGS Analysis.

Authorship 1823119
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author rank in publication: 8
linked author: Lange, Christoph
linked information resource: Recent advances in the treatment of tuberculosis.

Authorship 1824929
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author rank in publication: 9
linked author: Lange, Christoph
linked information resource: Transrenal Mycobacterium tuberculosis DNA in pulmonary tuberculosis patients during the first 14 days of treatment.

Authorship 1825367
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linked author: Lange, Christoph
linked information resource: Treatment outcomes of extensively drug-resistant tuberculosis in Europe: a retrospective cohort study.

Authorship 1826293
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author rank in publication: 44
linked author: Lange, Christoph
linked information resource: Diagnostic accuracy and predictive value of the QuantiFERON-TB gold plus assay for tuberculosis in immunocompromised individuals: a prospective TBnet study.

Authorship 1827442
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author rank in publication: 22
linked author: Lange, Christoph
linked information resource: A calcium-sensing receptor allelic series and underdiagnosis of genetically driven hypocalcemia.

Authorship 1830203
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author rank in publication: 5
linked author: Lange, Christoph
linked information resource: Availability of drugs and resistance testing for bedaquiline, pretomanid, linezolid, and moxifloxacin (BPaL(M)) regimen for rifampicin-resistant tuberculosis in Europe.

Authorship 1832481
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author rank in publication: 11
linked author: Lange, Christoph
linked information resource: Screening and targeted sequencing of stool for microbiologic confirmation and drug resistance determination in paucibacillary tuberculosis.

Authorship 1833627
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author rank in publication: 5
linked author: Lange, Christoph
linked information resource: Mycobacterium florentinum pulmonary disease: a case report and review of the literature.

Authorship 1832358
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author rank in publication: 12
linked author: Lange, Christoph
linked information resource: Lipoarabinomannan (LAM) for the diagnosis of tuberculosis from sputum.

Authorship 1833396
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author rank in publication: 44
linked author: Lange, Christoph
linked information resource: https://connects.catalyst.harvard.edu/Profiles/profile/323019287

Authorship 1834746
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author rank in publication: 11
linked author: Lange, Christoph
linked information resource: Treatment of MDR, Pre-XDR, XDR, and Rifampicin-Resistant Tuberculosis or in Case of Intolerance to at Least Rifampicin in Austria, Germany, and Switzerland.

Authorship 1834726
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author rank in publication: 4
linked author: Lange, Christoph
linked information resource: (Re-)introduction of TNF antagonists and JAK inhibitors in patients with previous tuberculosis: a systematic review.

Authorship 1837551
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author rank in publication: 5
linked author: Lange, Christoph
linked information resource: Novel drugs against tuberculosis: a clinician's perspective.

Authorship 1835488
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author rank in publication: 8
linked author: Lange, Christoph
linked information resource: Tuberculosis in people of Ukrainian origin in the European Union and the European Economic Area, 2019 to 2022.

Authorship 1838185
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author rank in publication: 6
linked author: Lange, Christoph
linked information resource: Serial measurements of transrenal mycobacterial DNA as indicators of the early bactericidal activity (EBA) of antituberculosis drugs.

Authorship 1837801
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author rank in publication: 2
linked author: Lange, Christoph
linked information resource: Tuberculosis preventive chemotherapy: the times they are a-changin'.

Authorship 1838074
type: Authorship
author rank in publication: 9
linked author: Lange, Christoph
linked information resource: Risk for latent and active tuberculosis in Germany.

Authorship 1840095
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author rank in publication: 3
linked author: Lange, Christoph
linked information resource: Treatment of Nontuberculous Mycobacterial Pulmonary Disease: An Official ATS/ERS/ESCMID/IDSA Clinical Practice Guideline.

Authorship 1838094
type: Authorship
author rank in publication: 6
linked author: Lange, Christoph
linked information resource: T-Cell Therapy: Options for Infectious Diseases.

Authorship 1839215
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author rank in publication: 13
linked author: Lange, Christoph
linked information resource: Relapse-free cure from multidrug-resistant tuberculosis in Germany.

Authorship 1838128
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author rank in publication: 8
linked author: Lange, Christoph
linked information resource: In reply.

Authorship 1838894
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linked author: Lange, Christoph
linked information resource: Pulmonary immune responses to Mycobacterium tuberculosis in exposed individuals.

Authorship 1839060
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author rank in publication: 22
linked author: Lange, Christoph
linked information resource: Integrating standardized whole genome sequence analysis with a global Mycobacterium tuberculosis antibiotic resistance knowledgebase.

Authorship 1839058
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author rank in publication: 4
linked author: Lange, Christoph
linked information resource: Pathogen-based precision medicine for drug-resistant tuberculosis.

Authorship 1840081
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author rank in publication: 22
linked author: Lange, Christoph
linked information resource: Author Correction: Integrating standardized whole genome sequence analysis with a global Mycobacterium tuberculosis antibiotic resistance knowledgebase.

Authorship 1841644
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author rank in publication: 14
linked author: Lange, Christoph
linked information resource: Predictive performance of interferon-gamma release assays and the tuberculin skin test for incident tuberculosis: an individual participant data meta-analysis.

Authorship 1840382
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author rank in publication: 1
linked author: Lange, Christoph
linked information resource: Sorry for the delay.

Authorship 1844268
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author rank in publication: 12
linked author: Lange, Christoph
linked information resource: Inclusion of patient-centered, non-microbiological endpoints and biomarkers in tuberculosis drug trials.

Authorship 1840792
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author rank in publication: 2
linked author: Lange, Christoph
linked information resource: A revolution in the management of multidrug-resistant tuberculosis.

Authorship 1841944
type: Authorship
author rank in publication: 5
linked author: Lange, Christoph
linked information resource: Pathogenesis of tuberculosis: the 1930 Lübeck disaster revisited.

Authorship 1843651
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author rank in publication: 5
linked author: Lange, Christoph
linked information resource: Rolling out new anti-tuberculosis drugs without diagnostic capacity.

Authorship 1841252
type: Authorship
author rank in publication: 5
linked author: Lange, Christoph
linked information resource: Carl Flügge, one of the last holistic hygienists and discoverer of droplet transmission of infectious diseases.

Authorship 1842401
type: Authorship
author rank in publication: 4
linked author: Lange, Christoph
linked information resource: Availability and costs of medicines for the treatment of tuberculosis in Europe.

Authorship 1842609
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author rank in publication: 3
linked author: Lange, Christoph
linked information resource: Artificial intelligence in tuberculosis: a new ally in disease control.

Authorship 1842650
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author rank in publication: 22
linked author: Lange, Christoph
linked information resource: Tuberculosis in adult migrants in Europe: a TBnet consensus statement.

Authorship 1842699
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author rank in publication: 3
linked author: Lange, Christoph
linked information resource: Post-tuberculosis lung impairment: systematic review and meta-analysis of spirometry data from 14?621 people.

Authorship 1845742
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author rank in publication: 4
linked author: Lange, Christoph
linked information resource: Treatment-shortening regimens for tuberculosis: updates and future priorities.

Authorship 1843530
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author rank in publication: 5
linked author: Lange, Christoph
linked information resource: Shifting tuberculosis dynamics in the EU/EEA: geographical and drug resistance trends among people of foreign origin, 2019 to 2023.

Authorship 1843360
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author rank in publication: 5
linked author: Lange, Christoph
linked information resource: Tuberculosis: current challenges and beyond.

Authorship 1842610
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author rank in publication: 3
linked author: Lange, Christoph
linked information resource: Advances in tuberculosis biomarkers: unravelling risk factors, active disease and treatment success.

Authorship 1842696
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author rank in publication: 8
linked author: Lange, Christoph
linked information resource: Impact of drug-resistant tuberculosis on socio-economic status, quality of life and psychological well-being of patients in Bucharest, Romania: a prospective cohort study.

Authorship 1843839
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author rank in publication: 9
linked author: Lange, Christoph
linked information resource: Co-administration of treatment for rifampicin-resistant TB and chronic HCV infection: A TBnet and ESGMYC study.

Authorship 1844901
type: Authorship
author rank in publication: 5
linked author: Lange, Christoph
linked information resource: Serratia sp. traits distinguish the lung microbiome of patients with tuberculosis and non-tuberculous mycobacterial lung diseases.

Authorship 1846191
type: Authorship
author rank in publication: 5
linked author: Lange, Christoph
linked information resource: Tuberculosis screening in migrants to the EU/EEA and UK.

Authorship 1845729
type: Authorship
author rank in publication: 9
linked author: Lange, Christoph
linked information resource: Impact of Mycobacterium tuberculosis strain type on multidrug-resistant tuberculosis severity, Republic of Moldova.

Authorship 1848312
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author rank in publication: 14
linked author: Lange, Christoph
linked information resource: Molecular hallmarks of excitatory and inhibitory neuronal resilience to Alzheimer's disease.

Authorship 1847888
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author rank in publication: 10
linked author: Lange, Christoph
linked information resource: High rates of acquired resistance to fluoroquinolones, bedaquiline, and linezolid in patients failing treatment against drug-resistant tuberculosis in the Republic of Moldova.

Authorship 1850289
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author rank in publication: 2
linked author: Lange, Christoph
linked information resource: Aspergillus-specific IgG antibodies for diagnosing chronic pulmonary aspergillosis compared with the reference standard-author's reply.

Authorship 1851271
type: Authorship
author rank in publication: 6
linked author: Lange, Christoph
linked information resource: Analyzing associations and higher-order effects in multi-omics data with double machine learning.

Authorship 1853135
type: Authorship
author rank in publication: 4
linked author: Lange, Christoph
linked information resource: https://connects.catalyst.harvard.edu/Profiles/profile/323033975

Authorship 1853293
type: Authorship
author rank in publication: 4
linked author: Lange, Christoph
linked information resource: Clinical spectrum and relevance of Mycobacterium malmoense: Systematic review and meta-analysis of 859 patients.

Authorship 1853137
type: Authorship
author rank in publication: 12
linked author: Lange, Christoph
linked information resource: Developing biomarker assays to accelerate tuberculosis drug development: defining target product profiles.

Authorship 1853277
type: Authorship
author rank in publication: 1
linked author: Lange, Christoph
linked information resource: Availability of drugs and resistance testing for bedaquiline, pretomanid, linezolid, and moxifloxacin (BPaL(M)) regimen for rifampicin-resistant tuberculosis in Europe: author's response.

Pulmonary immune responses to Mycobacterium tuberculosis in exposed individuals.
PubMed Identifier: 29125874
author list: Herzmann C, Ernst M, Lange C, Stenger S, Kaufmann SHE, Reiling N, Schaberg T, van der Merwe L, Maertzdorf J
published in: PloS one
information resource reference: Pulmonary immune responses to Mycobacterium tuberculosis in exposed individuals. PLoS One. 2017; 12(11):e0187882.
journal title abbreviation: PLoS One
publication date: 2017-11-10T00:00:00
year: 2017
type: Academic Article
type: Article
type: Document
type: Information Resource

Integrating standardized whole genome sequence analysis with a global Mycobacterium tuberculosis antibiotic resistance knowledgebase.
PubMed Identifier: 30337678
author list: Ezewudo M, Borens A, Chiner-Oms Á, Miotto P, Chindelevitch L, Starks AM, Hanna D, Liwski R, Zignol M, Gilpin C, Niemann S, Kohl TA, Warren RM, Crook D, Gagneux S, Hoffner S, Rodrigues C, Comas I, Engelthaler DM, Alland D, Rigouts L, Lange C, Dheda K, Hasan R, McNerney R, Cirillo DM, Schito M, Rodwell TC, Posey J
published in: Scientific reports
information resource reference: Integrating standardized whole genome sequence analysis with a global Mycobacterium tuberculosis antibiotic resistance knowledgebase. Sci Rep. 2018 10 18; 8(1):15382.
journal title abbreviation: Sci Rep
publication date: 2018-10-18T00:00:00
year: 2018
type: Academic Article
type: Article
type: Document
type: Information Resource

Emergence of bedaquiline resistance in a high tuberculosis burden country.
PubMed Identifier: 34503982
author list: Chesov E, Chesov D, Maurer FP, Andres S, Utpatel C, Barilar I, Donica A, Reimann M, Niemann S, Lange C, Crudu V, Heyckendorf J, Merker M
published in: The European respiratory journal
information resource reference: Emergence of bedaquiline resistance in a high tuberculosis burden country. Eur Respir J. 2022 03; 59(3).
journal title abbreviation: Eur Respir J
publication date: 2022-03-24T00:00:00
year: 2022
type: Academic Article
type: Article
type: Document
type: Information Resource

Rifapentine access in Europe: growing concerns over key tuberculosis treatment component.
PubMed Identifier: 35589114
author list: Guglielmetti L, Günther G, Leu C, Cirillo D, Duarte R, Garcia-Basteiro AL, Goletti D, Jankovic M, Kuksa L, Maurer FP, Méchaï F, Tiberi S, van Leth F, Veziris N, Lange C
published in: The European respiratory journal
information resource reference: Rifapentine access in Europe: growing concerns over key tuberculosis treatment component. Eur Respir J. 2022 05; 59(5).
journal title abbreviation: Eur Respir J
publication date: 2022-05-19T00:00:00
year: 2022
type: Academic Article
type: Article
type: Document
type: Information Resource

The TB27 Transcriptomic Model for Predicting Mycobacterium tuberculosis Culture Conversion.
PubMed Identifier: 39911144
author list: Reimann M, Avsar K, DiNardo AR, Goldmann T, Günther G, Hoelscher M, Ibraim E, Kalsdorf B, Kaufmann SHE, Köhler N, Mandalakas AM, Maurer FP, Müller M, Nitschkowski D, Olaru ID, Popa C, Rachow A, Rolling T, Salzer HJF, Sanchez-Carballo P, Schuhmann M, Schaub D, Spinu V, Terhalle E, Unnewehr M, Zielinski NJ, Heyckendorf J, Lange C
published in: Pathogens & immunity
information resource reference: The TB27 Transcriptomic Model for Predicting Mycobacterium tuberculosis Culture Conversion. Pathog Immun. 2024; 10(1):120-139.
journal title abbreviation: Pathog Immun
publication date: 2025-01-29T00:00:00
year: 2025
type: Academic Article
type: Article
type: Document
type: Information Resource

Lipoarabinomannan (LAM) for the diagnosis of tuberculosis from sputum.
PubMed Identifier: 41265528
author list: Pichlo S, Carballo PS, Reimann M, Zielinski N, Shuaib YA, Köhler N, Andres S, Heyckendorf J, Kalsdorf B, Olaru ID, Salzer HJF, Lange C
published in: The Journal of infection
information resource reference: Lipoarabinomannan (LAM) for the diagnosis of tuberculosis from sputum. J Infect. 2025 Dec; 91(6):106662.
journal title abbreviation: J Infect
publication date: 2025-11-18T00:00:00
year: 2025
type: Academic Article
type: Article
type: Document
type: Information Resource

Molecular hallmarks of excitatory and inhibitory neuronal resilience to Alzheimer's disease.
PubMed Identifier: 41035073
author list: Castanho I, Naderi Yeganeh P, Boix CA, Morgan SL, Mathys H, Prokopenko D, White B, Soto LM, Pegoraro G, Shah S, Ploumakis A, Kalavros N, Bennett DA, Lange C, Kim DY, Bertram L, Tsai LH, Kellis M, Tanzi RE, Hide W
published in: Molecular neurodegeneration
information resource reference: Molecular hallmarks of excitatory and inhibitory neuronal resilience to Alzheimer's disease. Mol Neurodegener. 2025 Oct 01; 20(1):103.
journal title abbreviation: Mol Neurodegener
publication date: 2025-10-01T00:00:00
year: 2025
type: Academic Article
type: Article
type: Document
type: Information Resource

False-negative interferon-? release assay results in active tuberculosis: a TBNET study.
PubMed Identifier: 25359336
author list: de Visser V, Sotgiu G, Lange C, Aabye MG, Bakker M, Bartalesi F, Brat K, Chee CB, Dheda K, Dominguez J, Eyuboglu F, Ghanem M, Goletti D, Dilektasli AG, Guglielmetti L, Koh WJ, Latorre I, Losi M, Polanova M, Ravn P, Ringshausen FC, Rumetshofer R, de Souza-Galvão ML, Thijsen S, Bothamley G, Bossink A
published in: The European respiratory journal
information resource reference: False-negative interferon-? release assay results in active tuberculosis: a TBNET study. Eur Respir J. 2015 Jan; 45(1):279-83.
journal title abbreviation: Eur Respir J
publication date: 2014-10-30T00:00:00
year: 2014
type: Academic Article
type: Article
type: Document
type: Information Resource

Tuberculosis preventive chemotherapy: the times they are a-changin'.
PubMed Identifier: 26260815
author list: Dedicoat M, Lange C
published in: The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease
information resource reference: Tuberculosis preventive chemotherapy: the times they are a-changin'. Int J Tuberc Lung Dis. 2015 Sep; 19(9):1002.
journal title abbreviation: Int J Tuberc Lung Dis
publication date: 2015-09-01T00:00:00
year: 2015
type: Academic Article
type: Article
type: Document
type: Information Resource

Thermostability of IFN-? and IP-10 release assays for latent infection with Mycobacterium tuberculosis: A TBnet study.
PubMed Identifier: 27156612
author list: Blauenfeldt T, Wagner D, Aabye M, Heyckendorf J, Lange B, Lange C, Ernst M, Ravn P, Duarte R, Morais C, Hoffmann M, Schoch OD, Dominguez J, Latorre I, Ruhwald M
published in: Tuberculosis (Edinburgh, Scotland)
information resource reference: Thermostability of IFN-? and IP-10 release assays for latent infection with Mycobacterium tuberculosis: A TBnet study. Tuberculosis (Edinb). 2016 05; 98:7-12.
journal title abbreviation: Tuberculosis (Edinb)
publication date: 2015-05-15T00:00:00
year: 2015
type: Academic Article
type: Article
type: Document
type: Information Resource

Childhood BCG vaccination does not influence control of Mycobacterium tuberculosis growth by human bronchoalveolar lavage cells.
PubMed Identifier: 25794470
author list: Herzmann C, Sotgiu G, Schaberg T, Ernst M, Stenger S, Lange C
published in: Tuberculosis (Edinburgh, Scotland)
information resource reference: Childhood BCG vaccination does not influence control of Mycobacterium tuberculosis growth by human bronchoalveolar lavage cells. Tuberculosis (Edinb). 2015 May; 95(3):321-7.
journal title abbreviation: Tuberculosis (Edinb)
publication date: 2015-02-28T00:00:00
year: 2015
type: Academic Article
type: Article
type: Document
type: Information Resource

Poor adherence to management guidelines in nontuberculous mycobacterial pulmonary diseases.
PubMed Identifier: 28182571
author list: van Ingen J, Wagner D, Gallagher J, Morimoto K, Lange C, Haworth CS, Floto RA, Adjemian J, Prevots DR, Griffith DE
published in: The European respiratory journal
information resource reference: Poor adherence to management guidelines in nontuberculous mycobacterial pulmonary diseases. Eur Respir J. 2017 02; 49(2).
journal title abbreviation: Eur Respir J
publication date: 2017-02-15T00:00:00
year: 2017
type: Academic Article
type: Article
type: Document
type: Information Resource

What Is Resistance? Impact of Phenotypic versus Molecular Drug Resistance Testing on Therapy for Multi- and Extensively Drug-Resistant Tuberculosis.
PubMed Identifier: 29133554
author list: Heyckendorf J, Andres S, Köser CU, Olaru ID, Schön T, Sturegård E, Beckert P, Schleusener V, Kohl TA, Hillemann D, Moradigaravand D, Parkhill J, Peacock SJ, Niemann S, Lange C, Merker M
published in: Antimicrobial agents and chemotherapy
information resource reference: What Is Resistance? Impact of Phenotypic versus Molecular Drug Resistance Testing on Therapy for Multi- and Extensively Drug-Resistant Tuberculosis. Antimicrob Agents Chemother. 2018 02; 62(2).
journal title abbreviation: Antimicrob Agents Chemother
publication date: 2018-01-25T00:00:00
year: 2018
type: Academic Article
type: Article
type: Document
type: Information Resource

Treatment outcomes of MDR-TB and HIV co-infection in Europe.
PubMed Identifier: 28596434
author list: Magis-Escurra C, Günther G, Lange C, Alexandru S, Altet N, Avsar K, Bang D, Barbuta R, Bothamley G, Ciobanu A, Crudu V, Davilovits M, Dedicoat M, Duarte R, Gualano G, Kunst H, de Lange W, Leimane V, McLaughlin AM, Muylle I, Polcová V, Popa C, Rumetshofer R, Skrahina A, Solodovnikova V, Spinu V, Tiberi S, Viiklepp P, van Leth F
published in: The European respiratory journal
information resource reference: Treatment outcomes of MDR-TB and HIV co-infection in Europe. Eur Respir J. 2017 06; 49(6).
journal title abbreviation: Eur Respir J
publication date: 2017-06-08T00:00:00
year: 2017
type: Academic Article
type: Article
type: Document
type: Information Resource

Drug-resistant tuberculosis: An update on disease burden, diagnosis and treatment.
PubMed Identifier: 29641838
author list: Lange C, Chesov D, Heyckendorf J, Leung CC, Udwadia Z, Dheda K
published in: Respirology (Carlton, Vic.)
information resource reference: Drug-resistant tuberculosis: An update on disease burden, diagnosis and treatment. Respirology. 2018 Jul; 23(7):656-673.
journal title abbreviation: Respirology
publication date: 2018-04-11T00:00:00
year: 2018
type: Academic Article
type: Article
type: Document
type: Information Resource

Bedaquiline-based treatment regimen for multidrug-resistant tuberculosis.
PubMed Identifier: 28529207
author list: Olaru ID, Heyckendorf J, Andres S, Kalsdorf B, Lange C
published in: The European respiratory journal
information resource reference: Bedaquiline-based treatment regimen for multidrug-resistant tuberculosis. Eur Respir J. 2017 05; 49(5).
journal title abbreviation: Eur Respir J
publication date: 2017-05-21T00:00:00
year: 2017
type: Academic Article
type: Article
type: Document
type: Information Resource

Standardised shorter regimens versus individualised longer regimens for rifampin- or multidrug-resistant tuberculosis.
PubMed Identifier: 31862767
author list: Abidi S, Achar J, Assao Neino MM, Bang D, Benedetti A, Brode S, Campbell JR, Casas EC, Conradie F, Dravniece G, du Cros P, Falzon D, Jaramillo E, Kuaban C, Lan Z, Lange C, Li PZ, Makhmudova M, Maug AKJ, Menzies D, Migliori GB, Miller A, Myrzaliev B, Ndjeka N, Noeske J, Parpieva N, Piubello A, Schwoebel V, Sikhondze W, Singla R, Souleymane MB, Trébucq A, Van Deun A, Viney K, Weyer K, Zhang BJ, Ahmad Khan F
published in: The European respiratory journal
information resource reference: Standardised shorter regimens versus individualised longer regimens for rifampin- or multidrug-resistant tuberculosis. Eur Respir J. 2020 03; 55(3).
journal title abbreviation: Eur Respir J
publication date: 2020-03-20T00:00:00
year: 2020
type: Academic Article
type: Article
type: Document
type: Information Resource

Changes in treatment for multidrug-resistant tuberculosis according to national income.
PubMed Identifier: 32586878
author list: Kwak N, Winters N, Campbell JR, Chan ED, Gegia M, Lange C, Lee M, Milanov V, Menzies D, Yim JJ
published in: The European respiratory journal
information resource reference: Changes in treatment for multidrug-resistant tuberculosis according to national income. Eur Respir J. 2020 11; 56(5).
journal title abbreviation: Eur Respir J
publication date: 2020-11-05T00:00:00
year: 2020
type: Academic Article
type: Article
type: Document
type: Information Resource

[Diagnostics and treatment of tuberculosis under immunotherapy for multiple sclerosis : Current status and recommendations in Germany].
PubMed Identifier: 31297574
author list: Bittner S, Engel S, Lange C, Weber MS, Haghikia A, Luessi F, Korn T, Klotz L, Bayas A, Paul F, Heesen C, Stangel M, Wildemann B, Bergh FT, Tackenberg B, Trebst C, Warnke C, Linker R, Kerschensteiner M, Zettl U, Tumani H, Brück W, Meuth SG, Kümpfel T, Hemmer B, Wiendl H, Gold R, Zipp F
published in: Der Nervenarzt
information resource reference: [Diagnostics and treatment of tuberculosis under immunotherapy for multiple sclerosis : Current status and recommendations in Germany]. Nervenarzt. 2019 Dec; 90(12):1245-1253.
journal title abbreviation: Nervenarzt
publication date: 2019-12-01T00:00:00
year: 2019
type: Academic Article
type: Article
type: Document
type: Information Resource

Pathogen-based precision medicine for drug-resistant tuberculosis.
PubMed Identifier: 30335850
author list: Gröschel MI, Walker TM, van der Werf TS, Lange C, Niemann S, Merker M
published in: PLoS pathogens
information resource reference: Pathogen-based precision medicine for drug-resistant tuberculosis. PLoS Pathog. 2018 10; 14(10):e1007297.
journal title abbreviation: PLoS Pathog
publication date: 2018-10-18T00:00:00
year: 2018
type: Academic Article
type: Article
type: Document
type: Information Resource

Drug-associated adverse events in the treatment of multidrug-resistant tuberculosis: an individual patient data meta-analysis.
PubMed Identifier: 32192585
author list: Lan Z, Ahmad N, Baghaei P, Barkane L, Benedetti A, Brode SK, Brust JCM, Campbell JR, Chang VWL, Falzon D, Guglielmetti L, Isaakidis P, Kempker RR, Kipiani M, Kuksa L, Lange C, Laniado-Laborín R, Nahid P, Rodrigues D, Singla R, Udwadia ZF, Menzies D
published in: The Lancet. Respiratory medicine
information resource reference: Drug-associated adverse events in the treatment of multidrug-resistant tuberculosis: an individual patient data meta-analysis. Lancet Respir Med. 2020 04; 8(4):383-394.
journal title abbreviation: Lancet Respir Med
publication date: 2020-03-17T00:00:00
year: 2020
type: Academic Article
type: Article
type: Document
type: Information Resource

Challenging the management of drug-resistant tuberculosis - Authors' reply.
PubMed Identifier: 32145791
author list: Lange C, Dheda K, Chesov D, Mandalakas AM, Udwadia Z, Horsburgh CR
published in: Lancet (London, England)
information resource reference: Challenging the management of drug-resistant tuberculosis - Authors' reply. Lancet. 2020 03 07; 395(10226):783-784.
journal title abbreviation: Lancet
publication date: 2020-03-07T00:00:00
year: 2020
type: Academic Article
type: Article
type: Document
type: Information Resource

Treatment of Nontuberculous Mycobacterial Pulmonary Disease: An Official ATS/ERS/ESCMID/IDSA Clinical Practice Guideline.
PubMed Identifier: 32797222
author list: Daley CL, Iaccarino JM, Lange C, Cambau E, Wallace RJ, Andrejak C, Böttger EC, Brozek J, Griffith DE, Guglielmetti L, Huitt GA, Knight SL, Leitman P, Marras TK, Olivier KN, Santin M, Stout JE, Tortoli E, van Ingen J, Wagner D, Winthrop KL
published in: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
information resource reference: Treatment of Nontuberculous Mycobacterial Pulmonary Disease: An Official ATS/ERS/ESCMID/IDSA Clinical Practice Guideline. Clin Infect Dis. 2020 08 14; 71(4):905-913.
journal title abbreviation: Clin Infect Dis
publication date: 2020-08-14T00:00:00
year: 2020
type: Academic Article
type: Article
type: Document
type: Information Resource

Case Report: Hemophagocytic Lymphohistiocytosis and Non-Tuberculous Mycobacteriosis Caused by a Novel GATA2 Variant.
PubMed Identifier: 34040617
author list: Mika T, Vangala D, Eckhardt M, La Rosée P, Lange C, Lehmberg K, Wohlschläger C, Biskup S, Fuchs I, Mann J, Ehl S, Warnatz K, Schroers R
published in: Frontiers in immunology
information resource reference: Case Report: Hemophagocytic Lymphohistiocytosis and Non-Tuberculous Mycobacteriosis Caused by a Novel GATA2 Variant. Front Immunol. 2021; 12:682934.
journal title abbreviation: Front Immunol
publication date: 2021-05-10T00:00:00
year: 2021
type: Academic Article
type: Article
type: Document
type: Information Resource

Evidence-based Definition for Extensively Drug-Resistant Tuberculosis.
PubMed Identifier: 34107231
author list: Roelens M, Battista Migliori G, Rozanova L, Estill J, Campbell JR, Cegielski JP, Tiberi S, Palmero D, Fox GJ, Guglielmetti L, Sotgiu G, Brust JCM, Bang D, Lienhardt C, Lange C, Menzies D, Keiser O, Raviglione M
published in: American journal of respiratory and critical care medicine
information resource reference: Evidence-based Definition for Extensively Drug-Resistant Tuberculosis. Am J Respir Crit Care Med. 2021 09 15; 204(6):713-722.
journal title abbreviation: Am J Respir Crit Care Med
publication date: 2021-09-15T00:00:00
year: 2021
type: Academic Article
type: Article
type: Document
type: Information Resource

Discovery and validation of a personalized risk predictor for incident tuberculosis in low transmission settings.
PubMed Identifier: 33077958
author list: Gupta RK, Calderwood CJ, Yavlinsky A, Krutikov M, Quartagno M, Aichelburg MC, Altet N, Diel R, Dobler CC, Dominguez J, Doyle JS, Erkens C, Geis S, Haldar P, Hauri AM, Hermansen T, Johnston JC, Lange C, Lange B, van Leth F, Muñoz L, Roder C, Romanowski K, Roth D, Sester M, Sloot R, Sotgiu G, Woltmann G, Yoshiyama T, Zellweger JP, Zenner D, Aldridge RW, Copas A, Rangaka MX, Lipman M, Noursadeghi M, Abubakar I
published in: Nature medicine
information resource reference: Discovery and validation of a personalized risk predictor for incident tuberculosis in low transmission settings. Nat Med. 2020 12; 26(12):1941-1949.
journal title abbreviation: Nat Med
publication date: 2020-10-19T00:00:00
year: 2020
type: Academic Article
type: Article
type: Document
type: Information Resource

Pathogen-free diagnosis of tuberculosis.
PubMed Identifier: 34331877
author list: Heyckendorf J, Reimann M, Marwitz S, Lange C
published in: The Lancet. Infectious diseases
information resource reference: Pathogen-free diagnosis of tuberculosis. Lancet Infect Dis. 2021 08; 21(8):1066.
journal title abbreviation: Lancet Infect Dis
publication date: 2021-08-01T00:00:00
year: 2021
type: Academic Article
type: Article
type: Document
type: Information Resource

Alveolar macrophages from persons living with HIV show impaired epigenetic response to Mycobacterium tuberculosis.
PubMed Identifier: 34473646
author list: Correa-Macedo W, Fava VM, Orlova M, Cassart P, Olivenstein R, Sanz J, Xu YZ, Dumaine A, Sindeaux RH, Yotova V, Pacis A, Girouard J, Kalsdorf B, Lange C, Routy JP, Barreiro LB, Schurr E
published in: The Journal of clinical investigation
information resource reference: Alveolar macrophages from persons living with HIV show impaired epigenetic response to Mycobacterium tuberculosis. J Clin Invest. 2021 11 15; 131(22).
journal title abbreviation: J Clin Invest
publication date: 2021-11-15T00:00:00
year: 2021
type: Academic Article
type: Article
type: Document
type: Information Resource

Consensus management recommendations for less common non-tuberculous mycobacterial pulmonary diseases.
PubMed Identifier: 35090639
author list: Lange C, Böttger EC, Cambau E, Griffith DE, Guglielmetti L, van Ingen J, Knight SL, Marras TK, Olivier KN, Santin M, Stout JE, Tortoli E, Wagner D, Winthrop K, Daley CL
published in: The Lancet. Infectious diseases
information resource reference: Consensus management recommendations for less common non-tuberculous mycobacterial pulmonary diseases. Lancet Infect Dis. 2022 07; 22(7):e178-e190.
journal title abbreviation: Lancet Infect Dis
publication date: 2022-01-25T00:00:00
year: 2022
type: Academic Article
type: Article
type: Document
type: Information Resource

Perspective for Precision Medicine for Tuberculosis.
PubMed Identifier: 33117351
author list: Lange C, Aarnoutse R, Chesov D, van Crevel R, Gillespie SH, Grobbel HP, Kalsdorf B, Kontsevaya I, van Laarhoven A, Nishiguchi T, Mandalakas A, Merker M, Niemann S, Köhler N, Heyckendorf J, Reimann M, Ruhwald M, Sanchez-Carballo P, Schwudke D, Waldow F, DiNardo AR
published in: Frontiers in immunology
information resource reference: Perspective for Precision Medicine for Tuberculosis. Front Immunol. 2020; 11:566608.
journal title abbreviation: Front Immunol
publication date: 2020-10-08T00:00:00
year: 2020
type: Academic Article
type: Article
type: Document
type: Information Resource

Rapid molecular diagnostics of tuberculosis resistance by targeted stool sequencing.
PubMed Identifier: 35585607
author list: Sibandze DB, Kay A, Dreyer V, Sikhondze W, Dlamini Q, DiNardo A, Mtetwa G, Lukhele B, Vambe D, Lange C, Glenn Dlamini M, Ness T, Mejia R, Kalsdorf B, Heyckendorf J, Kuhns M, Maurer FP, Dlamini S, Maphalala G, Niemann S, Mandalakas A
published in: Genome medicine
information resource reference: Rapid molecular diagnostics of tuberculosis resistance by targeted stool sequencing. Genome Med. 2022 05 19; 14(1):52.
journal title abbreviation: Genome Med
publication date: 2022-05-19T00:00:00
year: 2022
type: Academic Article
type: Article
type: Document
type: Information Resource

Perspectives for systems biology in the management of tuberculosis.
PubMed Identifier: 34039674
author list: Kontsevaya I, Lange C, Comella-Del-Barrio P, Coarfa C, DiNardo AR, Gillespie SH, Hauptmann M, Leschczyk C, Mandalakas AM, Martinecz A, Merker M, Niemann S, Reimann M, Rzhepishevska O, Schaible UE, Scheu KM, Schurr E, Abel Zur Wiesch P, Heyckendorf J
published in: European respiratory review : an official journal of the European Respiratory Society
information resource reference: Perspectives for systems biology in the management of tuberculosis. Eur Respir Rev. 2021 Jun 30; 30(160).
journal title abbreviation: Eur Respir Rev
publication date: 2021-05-25T00:00:00
year: 2021
type: Academic Article
type: Article
type: Document
type: Information Resource

Gene expression signatures identify biologically and clinically distinct tuberculosis endotypes.
PubMed Identifier: 35169026
author list: DiNardo AR, Gandhi T, Heyckendorf J, Grimm SL, Rajapakshe K, Nishiguchi T, Reimann M, Kirchner HL, Kahari J, Dlamini Q, Lange C, Goldmann T, Marwitz S, Cirillo JD, Kaufmann SHE, Netea MG, van Crevel R, Mandalakas AM, Coarfa C
published in: The European respiratory journal
information resource reference: Gene expression signatures identify biologically and clinically distinct tuberculosis endotypes. Eur Respir J. 2022 09; 60(3).
journal title abbreviation: Eur Respir J
publication date: 2022-09-15T00:00:00
year: 2022
type: Academic Article
type: Article
type: Document
type: Information Resource

Long-term treatment outcomes in patients with multidrug-resistant tuberculosis.
PubMed Identifier: 36842637
author list: Maier C, Chesov D, Schaub D, Kalsdorf B, Andres S, Friesen I, Reimann M, Lange C
published in: Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases
information resource reference: Long-term treatment outcomes in patients with multidrug-resistant tuberculosis. Clin Microbiol Infect. 2023 Jun; 29(6):751-757.
journal title abbreviation: Clin Microbiol Infect
publication date: 2023-02-25T00:00:00
year: 2023
type: Academic Article
type: Article
type: Document
type: Information Resource

Long-term multidrug- and rifampicin-resistant tuberculosis treatment outcome by new WHO definitions in Germany.
PubMed Identifier: 36423919
author list: Otto-Knapp R, Häcker B, Krieger D, Stete K, Starzacher K, Maier C, Heyckendorf J, Avsar K, Suárez I, Rybniker J, Bauer T, Günther G, Lange C
published in: The European respiratory journal
information resource reference: Long-term multidrug- and rifampicin-resistant tuberculosis treatment outcome by new WHO definitions in Germany. Eur Respir J. 2022 11; 60(5).
journal title abbreviation: Eur Respir J
publication date: 2022-11-24T00:00:00
year: 2022
type: Academic Article
type: Article
type: Document
type: Information Resource

Increased protease-activated receptor 1 autoantibodies are associated with severe COVID-19.
PubMed Identifier: 36575710
author list: Tran F, Harris DMM, Scharmacher A, Graßhoff H, Sterner K, Schinke S, Käding N, Humrich JY, Cabral-Marques O, Bernardes JP, Mishra N, Bahmer T, Franzenburg J, Hoyer BF, Glück A, Guggeis M, Ossysek A, Küller A, Frank D, Lange C, Rupp J, Heyckendorf J, Gaede KI, Amital H, Rosenstiel P, Shoenfeld Y, Halpert G, Rosenberg AZ, Schulze-Forster K, Heidecke H, Riemekasten G, Schreiber S
published in: ERJ open research
information resource reference: Increased protease-activated receptor 1 autoantibodies are associated with severe COVID-19. ERJ Open Res. 2022 Oct; 8(4).
journal title abbreviation: ERJ Open Res
publication date: 2022-12-27T00:00:00
year: 2022
type: Academic Article
type: Article
type: Document
type: Information Resource

Treatments of Multidrug-Resistant Tuberculosis: Light at the End of the Tunnel.
PubMed Identifier: 35320062
author list: Lange C, Barry CE, Horsburgh CR
published in: American journal of respiratory and critical care medicine
information resource reference: Treatments of Multidrug-Resistant Tuberculosis: Light at the End of the Tunnel. Am J Respir Crit Care Med. 2022 05 15; 205(10):1142-1144.
journal title abbreviation: Am J Respir Crit Care Med
publication date: 2022-05-15T00:00:00
year: 2022
type: Academic Article
type: Article
type: Document
type: Information Resource

Tuberculosis: current challenges and beyond.
PubMed Identifier: 37334103
author list: Villar-Hernández R, Ghodousi A, Konstantynovska O, Duarte R, Lange C, Raviglione M
published in: Breathe (Sheffield, England)
information resource reference: Tuberculosis: current challenges and beyond. Breathe (Sheff). 2023 Mar; 19(1):220166.
journal title abbreviation: Breathe (Sheff)
publication date: 2023-04-11T00:00:00
year: 2023
type: Academic Article
type: Article
type: Document
type: Information Resource

Treatment-shortening regimens for tuberculosis: updates and future priorities.
PubMed Identifier: 37830101
author list: Saluzzo F, Adepoju VA, Duarte R, Lange C, Phillips PPJ
published in: Breathe (Sheffield, England)
information resource reference: Treatment-shortening regimens for tuberculosis: updates and future priorities. Breathe (Sheff). 2023 Sep; 19(3):230028.
journal title abbreviation: Breathe (Sheff)
publication date: 2023-10-10T00:00:00
year: 2023
type: Academic Article
type: Article
type: Document
type: Information Resource

Pretomanid-resistant tuberculosis.
PubMed Identifier: 36738862
author list: Koehler N, Andres S, Merker M, Dreyer V, John A, Kuhns M, Krieger D, Choong E, Verougstraete N, Zur Wiesch PA, Wicha SG, König C, Kalsdorf B, Sanchez Carballo PM, Schaub D, Werngren J, Schön T, Peloquin CA, Schönfeld N, Verstraete AG, Decosterd LA, Aarnoutse R, Niemann S, Maurer FP, Lange C
published in: The Journal of infection
information resource reference: Pretomanid-resistant tuberculosis. J Infect. 2023 05; 86(5):520-524.
journal title abbreviation: J Infect
publication date: 2023-02-02T00:00:00
year: 2023
type: Academic Article
type: Article
type: Document
type: Information Resource

Predictive performance of interferon-gamma release assays and the tuberculin skin test for incident tuberculosis: an individual participant data meta-analysis.
PubMed Identifier: 36636295
author list: Hamada Y, Gupta RK, Quartagno M, Izzard A, Acuna-Villaorduna C, Altet N, Diel R, Dominguez J, Floyd S, Gupta A, Huerga H, Jones-López EC, Kinikar A, Lange C, van Leth F, Liu Q, Lu W, Lu P, Rueda IL, Martinez L, Mbandi SK, Muñoz L, Padilla ES, Paradkar M, Scriba T, Sester M, Shanaube K, Sharma SK, Sloot R, Sotgiu G, Thiruvengadam K, Vashishtha R, Abubakar I, Rangaka MX
published in: EClinicalMedicine
information resource reference: Predictive performance of interferon-gamma release assays and the tuberculin skin test for incident tuberculosis: an individual participant data meta-analysis. EClinicalMedicine. 2023 Feb; 56:101815.
journal title abbreviation: EClinicalMedicine
publication date: 2023-01-05T00:00:00
year: 2023
type: Academic Article
type: Article
type: Document
type: Information Resource

Treatment of MDR, Pre-XDR, XDR, and Rifampicin-Resistant Tuberculosis or in Case of Intolerance to at Least Rifampicin in Austria, Germany, and Switzerland.
PubMed Identifier: 38810608
author list: Otto-Knapp R, Bauer T, Brinkmann F, Feiterna-Sperling C, Friesen I, Geerdes-Fenge H, Hartmann P, Häcker B, Heyckendorf J, Kuhns M, Lange C, Maurer FP, Nienhaus A, Priwitzer M, Richter E, Salzer HJF, Schoch OD, Schönfeld N, Schaberg T
published in: Respiration; international review of thoracic diseases
information resource reference: Treatment of MDR, Pre-XDR, XDR, and Rifampicin-Resistant Tuberculosis or in Case of Intolerance to at Least Rifampicin in Austria, Germany, and Switzerland. Respiration. 2024; 103(9):593-600.
journal title abbreviation: Respiration
publication date: 2024-05-29T00:00:00
year: 2024
type: Academic Article
type: Article
type: Document
type: Information Resource

Transrenal Mycobacterium tuberculosis DNA in pulmonary tuberculosis patients during the first 14 days of treatment.
PubMed Identifier: 37882572
author list: Kontsevaya I, Heyckendorf J, Koops F, Hillemann D, Goldmann T, Upton CM, De Jager V, Diacon A, Lange C
published in: Microbiology spectrum
information resource reference: Transrenal Mycobacterium tuberculosis DNA in pulmonary tuberculosis patients during the first 14 days of treatment. Microbiol Spectr. 2023 12 12; 11(6):e0234823.
journal title abbreviation: Microbiol Spectr
publication date: 2023-10-26T00:00:00
year: 2023
type: Academic Article
type: Article
type: Document
type: Information Resource

Availability of drugs and resistance testing for bedaquiline, pretomanid, linezolid, and moxifloxacin (BPaL(M)) regimen for rifampicin-resistant tuberculosis in Europe: author's response.
PubMed Identifier: 38901496
author list: Lange C, Kherabi Y, Guglielmetti L, Duarte R, Günther G
published in: Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases
information resource reference: Availability of drugs and resistance testing for bedaquiline, pretomanid, linezolid, and moxifloxacin (BPaL(M)) regimen for rifampicin-resistant tuberculosis in Europe: author's response. Clin Microbiol Infect. 2024 Sep; 30(9):1207-1208.
journal title abbreviation: Clin Microbiol Infect
publication date: 2024-06-18T00:00:00
year: 2024
type: Academic Article
type: Article
type: Document
type: Information Resource

A Single-Run HPLC-MS Multiplex Assay for Therapeutic Drug Monitoring of Relevant First- and Second-Line Antibiotics in the Treatment of Drug-Resistant Tuberculosis.
PubMed Identifier: 38004523
author list: Köhler N, Karaköse H, Grobbel HP, Hillemann D, Andres S, König C, Kalsdorf B, Brehm TT, Böttcher L, Friesen I, Hoffmann H, Strelec D, Schaub D, Peloquin CA, Schmiedel S, Decosterd LA, Choong E, Wicha SG, Aarnoutse RE, Lange C, Sánchez Carballo PM
published in: Pharmaceutics
information resource reference: A Single-Run HPLC-MS Multiplex Assay for Therapeutic Drug Monitoring of Relevant First- and Second-Line Antibiotics in the Treatment of Drug-Resistant Tuberculosis. Pharmaceutics. 2023 Oct 27; 15(11).
journal title abbreviation: Pharmaceutics
publication date: 2023-10-27T00:00:00
year: 2023
type: Academic Article
type: Article
type: Document
type: Information Resource

Artificial intelligence in tuberculosis: a new ally in disease control.
PubMed Identifier: 39660086
author list: McClean M, Panciu TC, Lange C, Duarte R, Theis F
published in: Breathe (Sheffield, England)
information resource reference: Artificial intelligence in tuberculosis: a new ally in disease control. Breathe (Sheff). 2024 Oct; 20(3):240056.
journal title abbreviation: Breathe (Sheff)
publication date: 2024-12-10T00:00:00
year: 2024
type: Academic Article
type: Article
type: Document
type: Information Resource

https://connects.catalyst.harvard.edu/Profiles/profile/323011892
PubMed Identifier: 39650575
author list: Fischer C, Siakavara M, Alter P, Vogelmeier CF, Speicher T, Pott H, Watz H, Bals R, Trudzinski F, Herth F, Ficker JH, Wagner M, Lange C, Stoycheva K, Randerath W, Behr J, Fähndrich S, Welte T, Pink I, Kahnert K, Seeger W, Kuhnert S, Gessler T, Adaskina N, Jörres RA
published in: Patient preference and adherence
information resource reference: Association of Patients' Knowledge on the Disease and Its Management with Indicators of Disease Severity and Individual Characteristics in Patients with Chronic Obstructive Pulmonary Disease (COPD): Results from COSYCONET 2. Patient Prefer Adherence. 2024; 18:2383-2393.
journal title abbreviation: Patient Prefer Adherence
publication date: 2024-12-02T00:00:00
year: 2024
type: Academic Article
type: Article
type: Document
type: Information Resource
label: Association of Patients' Knowledge on the Disease and Its Management with Indicators of Disease Severity and Individual Characteristics in Patients with Chronic Obstructive Pulmonary Disease (COPD): Results from COSYCONET 2.

A stool based qPCR for the diagnosis of TB in children and people living with HIV in Uganda, Eswatini and Mozambique (Stool4TB): a protocol for a multicenter diagnostic evaluation.
PubMed Identifier: 38383310
author list: Carratala-Castro L, Ssengooba W, Kay A, Acácio S, Ehrlich J, DiNardo AR, Shiba N, Nsubuga JK, Munguambe S, Saavedra-Cervera B, Manjate P, Mulengwa D, Sibandze B, Ziyane M, Kasule G, Mambuque E, Sekadde MP, Wobudeya E, Joloba ML, Heyckendorf J, Lange C, Hermans S, Mandalakas A, García-Basteiro AL, Lopez-Varela E
published in: BMC infectious diseases
information resource reference: A stool based qPCR for the diagnosis of TB in children and people living with HIV in Uganda, Eswatini and Mozambique (Stool4TB): a protocol for a multicenter diagnostic evaluation. BMC Infect Dis. 2024 Feb 21; 24(1):233.
journal title abbreviation: BMC Infect Dis
publication date: 2024-02-21T00:00:00
year: 2024
type: Academic Article
type: Article
type: Document
type: Information Resource

Towards shorter, safer, flexible, and more effective treatment regimens for drug-resistant tuberculosis.
PubMed Identifier: 39366401
author list: Dheda K, Lange C
published in: The Lancet. Respiratory medicine
information resource reference: Towards shorter, safer, flexible, and more effective treatment regimens for drug-resistant tuberculosis. Lancet Respir Med. 2024 Dec; 12(12):939-941.
journal title abbreviation: Lancet Respir Med
publication date: 2024-10-01T00:00:00
year: 2024
type: Academic Article
type: Article
type: Document
type: Information Resource

Revisiting diagnostics: high priority tuberculosis diagnostic tests that fill an unmet need: what we need and what we do not need.
PubMed Identifier: 39732394
author list: Lange C, Mandalakas AM, Lillebaek T, Chesov D, Dheda K, Saluzzo F
published in: Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases
information resource reference: Revisiting diagnostics: high priority tuberculosis diagnostic tests that fill an unmet need: what we need and what we do not need. Clin Microbiol Infect. 2025 Mar; 31(3):312-314.
journal title abbreviation: Clin Microbiol Infect
publication date: 2024-12-26T00:00:00
year: 2024
type: Academic Article
type: Article
type: Document
type: Information Resource

Tuberculosis in adult migrants in Europe: a TBnet consensus statement.
PubMed Identifier: 39672603
author list: Kunst H, Lange B, Hovardovska O, Bockey A, Zenner D, Andersen AB, Hargreaves S, Pareek M, Friedland JS, Wejse C, Bothamley G, Guglielmetti L, Chesov D, Tiberi S, Matteelli A, Mandalakas AM, Heyckendorf J, Eimer J, Malhotra A, Zamora J, Vasiliu A, Lange C
published in: The European respiratory journal
information resource reference: Tuberculosis in adult migrants in Europe: a TBnet consensus statement. Eur Respir J. 2025 Mar; 65(3).
journal title abbreviation: Eur Respir J
publication date: 2025-03-06T00:00:00
year: 2025
type: Academic Article
type: Article
type: Document
type: Information Resource

Preventive chemotherapy for contacts of MDR-TB: is the proof in the pudding?
PubMed Identifier: 25299855
author list: Lange C, Kampmann B
published in: The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease
information resource reference: Preventive chemotherapy for contacts of MDR-TB: is the proof in the pudding? Int J Tuberc Lung Dis. 2014 Nov; 18(11):1262-3.
journal title abbreviation: Int J Tuberc Lung Dis
publication date: 2014-11-01T00:00:00
year: 2014
type: Academic Article
type: Article
type: Document
type: Information Resource

Patients at risk of nontuberculous mycobacterial pulmonary disease who need testing evaluated using a modified Delphi process by European experts.
PubMed Identifier: 39319044
author list: Loebinger MR, Aliberti S, Haworth C, Jankovic Makek M, Lange C, Lorent N, Papavasileiou A, Polverino E, Rohde G, Veziris N, Wagner D, van Ingen J
published in: ERJ open research
information resource reference: Patients at risk of nontuberculous mycobacterial pulmonary disease who need testing evaluated using a modified Delphi process by European experts. ERJ Open Res. 2024 Sep; 10(5).
journal title abbreviation: ERJ Open Res
publication date: 2024-09-23T00:00:00
year: 2024
type: Academic Article
type: Article
type: Document
type: Information Resource

A novel method for detecting Lipoarabinomannan in urine with the promise of meeting the WHO target product profile for the diagnosis of tuberculosis.
PubMed Identifier: 40048961
author list: Budde K, Lange C, Reimann M, Zielinski N, Meiwes L, Köhler N, Carballo PS
published in: Tuberculosis (Edinburgh, Scotland)
information resource reference: A novel method for detecting Lipoarabinomannan in urine with the promise of meeting the WHO target product profile for the diagnosis of tuberculosis. Tuberculosis (Edinb). 2025 May; 152:102619.
journal title abbreviation: Tuberculosis (Edinb)
publication date: 2025-02-24T00:00:00
year: 2025
type: Academic Article
type: Article
type: Document
type: Information Resource

Tuberculosis in people of Ukrainian origin in the European Union and the European Economic Area, 2019 to 2022.
PubMed Identifier: 38516786
author list: Stoycheva K, Cristea V, Ködmön C, Rosales-Klintz S, Zenner D, Vasiliu A, van der Werf M, Lange C
published in: Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin
information resource reference: Tuberculosis in people of Ukrainian origin in the European Union and the European Economic Area, 2019 to 2022. Euro Surveill. 2024 Mar; 29(12).
journal title abbreviation: Euro Surveill
publication date: 2024-03-01T00:00:00
year: 2024
type: Academic Article
type: Article
type: Document
type: Information Resource

Performance of a Novel Stool Quantitative Polymerase Chain Reaction Assay for Pediatric Tuberculosis Detection in Sub-Saharan Africa.
PubMed Identifier: 40391711
author list: Vasiliu A, Carratala-Castro L, Seeger A, Ehrlich J, Nkala B, Ness T, Cumbe MM, Mulengwa D, Munguambe S, Mtafya B, Mambuque E, Shiba N, Acacio S, Komba L, Adu-Gyamfi CG, Kirchner HL, Lange C, DiNardo AR, Garcia-Basteiro AL, Mandalakas AM, Kay A
published in: Journal of the Pediatric Infectious Diseases Society
information resource reference: Performance of a Novel Stool Quantitative Polymerase Chain Reaction Assay for Pediatric Tuberculosis Detection in Sub-Saharan Africa. J Pediatric Infect Dis Soc. 2025 Jun 16; 14(6).
journal title abbreviation: J Pediatric Infect Dis Soc
publication date: 2025-06-16T00:00:00
year: 2025
type: Academic Article
type: Article
type: Document
type: Information Resource

A Transcriptomic Biomarker Predicting Linezolid-Associated Neuropathy During Treatment of Drug-Resistant Tuberculosis.
PubMed Identifier: 38939039
author list: Zielinski N, Baiceanu D, Dragomir A, Heyckendorf J, Ibraim E, Köhler N, Leschczyk C, Popa C, Rachow A, Sachsenweger J, Sanchez Carballo P, Schaub D, Zeeb H, Tulu B, DiNardo AR, Lange C, Reimann M
published in: Pathogens & immunity
information resource reference: A Transcriptomic Biomarker Predicting Linezolid-Associated Neuropathy During Treatment of Drug-Resistant Tuberculosis. Pathog Immun. 2024; 9(2):25-42.
journal title abbreviation: Pathog Immun
publication date: 2024-06-25T00:00:00
year: 2024
type: Academic Article
type: Article
type: Document
type: Information Resource

Candidate anti-tuberculosis medicines and regimens under clinical evaluation.
PubMed Identifier: 38909687
author list: Hoelscher M, Barros-Aguirre D, Dara M, Heinrich N, Sun E, Lange C, Tiberi S, Wells C
published in: Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases
information resource reference: Candidate anti-tuberculosis medicines and regimens under clinical evaluation. Clin Microbiol Infect. 2024 Sep; 30(9):1131-1138.
journal title abbreviation: Clin Microbiol Infect
publication date: 2024-06-22T00:00:00
year: 2024
type: Academic Article
type: Article
type: Document
type: Information Resource

Advances in tuberculosis biomarkers: unravelling risk factors, active disease and treatment success.
PubMed Identifier: 39660087
author list: Schildkraut JA, Köhler N, Lange C, Duarte R, Gillespie SH
published in: Breathe (Sheffield, England)
information resource reference: Advances in tuberculosis biomarkers: unravelling risk factors, active disease and treatment success. Breathe (Sheff). 2024 Oct; 20(3):240003.
journal title abbreviation: Breathe (Sheff)
publication date: 2024-12-10T00:00:00
year: 2024
type: Academic Article
type: Article
type: Document
type: Information Resource

Rapid tuberculosis diagnosis from respiratory or blood samples by a low cost, portable lab-in-tube assay.
PubMed Identifier: 40203083
author list: Youngquist BM, Saliba J, Kim Y, Cutro TJ, Lyon CJ, Olivo J, Ha N, Fine J, Colman R, Vergara C, Robinson J, LaCourse S, Garfein RS, Catanzaro DG, Lange C, Perez-Then E, Graviss EA, Mitchell CD, Rodwell T, Ning B, Hu TY
published in: Science translational medicine
information resource reference: Rapid tuberculosis diagnosis from respiratory or blood samples by a low cost, portable lab-in-tube assay. Sci Transl Med. 2025 Apr 09; 17(793):eadp6411.
journal title abbreviation: Sci Transl Med
publication date: 2025-04-09T00:00:00
year: 2025
type: Academic Article
type: Article
type: Document
type: Information Resource

Performance of stool Xpert MTB/RIF Ultra for detection of Mycobacterium tuberculosis among adults living with HIV: a multicentre, prospective diagnostic study.
PubMed Identifier: 40194533
author list: Kasule GW, Hermans S, Acacio S, Kay A, Nsubuga JK, Fernández-Escobar C, Shiba N, Carratalá-Castro L, Semugenze D, Mwachan P, Munguambe S, Ehrlich J, Lopez-Varela E, DiNardo AR, Cobelens F, Lange C, Joloba M, Mandalakas AM, Ssengooba W, García-Basteiro AL
published in: The Lancet. Microbe
information resource reference: Performance of stool Xpert MTB/RIF Ultra for detection of Mycobacterium tuberculosis among adults living with HIV: a multicentre, prospective diagnostic study. Lancet Microbe. 2025 Jul; 6(7):101085.
journal title abbreviation: Lancet Microbe
publication date: 2025-04-04T00:00:00
year: 2025
type: Academic Article
type: Article
type: Document
type: Information Resource

Serratia sp. traits distinguish the lung microbiome of patients with tuberculosis and non-tuberculous mycobacterial lung diseases.
PubMed Identifier: 40569902
author list: Belheouane M, Kalsdorf B, Niemann S, Gaede KI, Lange C, Heyckendorf J, Merker M
published in: PloS one
information resource reference: Serratia sp. traits distinguish the lung microbiome of patients with tuberculosis and non-tuberculous mycobacterial lung diseases. PLoS One. 2025; 20(6):e0325362.
journal title abbreviation: PLoS One
publication date: 2025-06-26T00:00:00
year: 2025
type: Academic Article
type: Article
type: Document
type: Information Resource

Shifting tuberculosis dynamics in the EU/EEA: geographical and drug resistance trends among people of foreign origin, 2019 to 2023.
PubMed Identifier: 40116035
author list: Vasiliu A, Cristea V, Stoycheva K, Rosales-Klintz S, Lange C, Zenner D, Ködmön C
published in: Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin
information resource reference: Shifting tuberculosis dynamics in the EU/EEA: geographical and drug resistance trends among people of foreign origin, 2019 to 2023. Euro Surveill. 2025 Mar; 30(11).
journal title abbreviation: Euro Surveill
publication date: 2025-03-01T00:00:00
year: 2025
type: Academic Article
type: Article
type: Document
type: Information Resource

Linezolid for the treatment of drug-resistant tuberculosis.
PubMed Identifier: 40846488
author list: Lange C, Barry C, Sotgiu G
published in: The European respiratory journal
information resource reference: Linezolid for the treatment of drug-resistant tuberculosis. Eur Respir J. 2025 Aug; 66(2).
journal title abbreviation: Eur Respir J
publication date: 2025-08-22T00:00:00
year: 2025
type: Academic Article
type: Article
type: Document
type: Information Resource

Diagnostic accuracy and predictive value of the QuantiFERON-TB gold plus assay for tuberculosis in immunocompromised individuals: a prospective TBnet study.
PubMed Identifier: 40823191
author list: Sester M, Altet-Gomez N, Andersen ÅB, Arias-Guillén M, Avsar K, Bakken Kran AM, Bothamley G, Nordholm Breschel AC, Brown J, Chesov D, Ciobanu N, Cirillo DM, Crudu V, de Souza Galvao M, Dilektasli AG, Dominguez J, Duarte R, Dyrhol-Riise AM, Goletti D, Hoffmann H, Ibraim E, Kalsdorf B, Krawczyk M, Kunst H, Lange B, Lipman M, Matteelli A, Milkiewicz P, Neyer D, Nitschke M, Oral HB, Palacios-Gutiérrez JJ, Petruccioli E, Raszeja-Wyszomirska J, Ravn P, Rupp J, Spohn HE, Toader C, Villar-Hernandez R, Wagner D, van Leth F, Martinez L, Pedersen OS, Lange C
published in: The Lancet regional health. Europe
information resource reference: Diagnostic accuracy and predictive value of the QuantiFERON-TB gold plus assay for tuberculosis in immunocompromised individuals: a prospective TBnet study. Lancet Reg Health Eur. 2025 Oct; 57:101416.
journal title abbreviation: Lancet Reg Health Eur
publication date: 2025-08-06T00:00:00
year: 2025
type: Academic Article
type: Article
type: Document
type: Information Resource

High rates of acquired resistance to fluoroquinolones, bedaquiline, and linezolid in patients failing treatment against drug-resistant tuberculosis in the Republic of Moldova.
PubMed Identifier: 40945720
author list: Chesov D, Reimann M, Mukherjee T, Tewatia K, Konstantynovska O, David A, Rusu D, Ciobanu N, Crudu V, Lange C
published in: Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases
information resource reference: High rates of acquired resistance to fluoroquinolones, bedaquiline, and linezolid in patients failing treatment against drug-resistant tuberculosis in the Republic of Moldova. Clin Microbiol Infect. 2026 Jan; 32(1):177-180.
journal title abbreviation: Clin Microbiol Infect
publication date: 2025-09-11T00:00:00
year: 2025
type: Academic Article
type: Article
type: Document
type: Information Resource

Factors associated with new onset of depression and anxiety symptoms differ by sex in the COPDGene study.
PubMed Identifier: 40840304
author list: Voorhies K, Fiedorowicz JG, Yohannes AM, Kinney GL, DeMeo DL, Regan EA, Crapo JD, Silverman EK, Lange C, Hoth KF, Lutz SM
published in: Journal of psychosomatic research
information resource reference: Factors associated with new onset of depression and anxiety symptoms differ by sex in the COPDGene study. J Psychosom Res. 2025 Oct; 197:112345.
journal title abbreviation: J Psychosom Res
publication date: 2025-08-07T00:00:00
year: 2025
type: Academic Article
type: Article
type: Document
type: Information Resource

Estimating the Accuracy and Additionality of TB-LAM to Diagnose TB in Children Without HIV (AccuLAM).
PubMed Identifier: 41208371
author list: Carratalà Castro L, Munguambe S, Kay A, Ssengooba W, Mulengwa D, Acácio S, Ehrlich J, DiNardo AR, Vasiliu A, Seeger A, Mambuque E, Adu-Gyamfi CG, Timoteo H, Lange C, Hermans S, Mandalakas A, López-Varela E, García-Basteiro AL
published in: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
information resource reference: Estimating the Accuracy and Additionality of TB-LAM to Diagnose TB in Children Without HIV (AccuLAM). Clin Infect Dis. 2026 Feb 25; 82(2):301-303.
journal title abbreviation: Clin Infect Dis
publication date: 2026-02-25T00:00:00
year: 2026
type: Academic Article
type: Article
type: Document
type: Information Resource

Screening and targeted sequencing of stool for microbiologic confirmation and drug resistance determination in paucibacillary tuberculosis.
PubMed Identifier: 41270009
author list: Ness TE, Ziyane M, Maphalala N, Seeger A, Vasiliu A, Khumalo W, Thunzini M, Dlamini S, Maphalala G, Gascua C, Lange C, Meyer S, Inman B, Dreyer V, Utpatel C, Niemann T, DiNardo A, Kay A, Niemann S, Mandalakas A
published in: PLOS global public health
information resource reference: Screening and targeted sequencing of stool for microbiologic confirmation and drug resistance determination in paucibacillary tuberculosis. PLOS Glob Public Health. 2025; 5(11):e0005243.
journal title abbreviation: PLOS Glob Public Health
publication date: 2025-11-21T00:00:00
year: 2025
type: Academic Article
type: Article
type: Document
type: Information Resource

Novel drugs against tuberculosis: a clinician's perspective.
PubMed Identifier: 25431273
author list: Olaru ID, von Groote-Bidlingmaier F, Heyckendorf J, Yew WW, Lange C, Chang KC
published in: The European respiratory journal
information resource reference: Novel drugs against tuberculosis: a clinician's perspective. Eur Respir J. 2015 Apr; 45(4):1119-31.
journal title abbreviation: Eur Respir J
publication date: 2014-11-27T00:00:00
year: 2014
type: Academic Article
type: Article
type: Document
type: Information Resource

https://connects.catalyst.harvard.edu/Profiles/profile/323019287
PubMed Identifier: 41399688
author list: Sester M, Altet-Gomez N, Andersen ÅB, Arias-Guillén M, Avsar K, Bakken Kran AM, Bothamley G, Nordholm Breschel AC, Brown J, Chesov D, Ciobanu N, Cirillo DM, Crudu V, de Souza Galvao M, Dilektasli AG, Dominguez J, Duarte R, Dyrhol-Riise AM, Goletti D, Hoffmann H, Ibraim E, Kalsdorf B, Krawczyk M, Kunst H, Lange B, Lipman M, Matteelli A, Milkiewicz P, Neyer D, Nitschke M, Oral HB, Palacios-Gutiérrez JJ, Petruccioli E, Raszeja-Wyszomirska J, Ravn P, Rupp J, Spohn HE, Toader C, Villar-Hernandez R, Wagner D, van Leth F, Martinez L, Pedersen OS, Lange C
published in: The Lancet regional health. Europe
information resource reference: Correction to Diagnostic accuracy and predictive value of the QuantiFERON-TB gold plus assay for tuberculosis in immunocompromised individuals: a prospective TBnet study Lancet Reg Health Eur 57 (2025) 101416 LLRHEUROPE-D-25-00310. Lancet Reg Health Eur. 2025 Dec; 59:101523.
journal title abbreviation: Lancet Reg Health Eur
publication date: 2025-11-26T00:00:00
year: 2025
type: Academic Article
type: Article
type: Document
type: Information Resource
label: Correction to Diagnostic accuracy and predictive value of the QuantiFERON-TB gold plus assay for tuberculosis in immunocompromised individuals: a prospective TBnet study Lancet Reg Health Eur 57 (2025) 101416 LLRHEUROPE-D-25-00310.

Editorial Commentary: 1, 2, 3 (Years)??…??and You're Out: The End of a 123-year Historic Era.
PubMed Identifier: 26839384
author list: DiNardo AR, Lange C, Mandalakas AM
published in: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
information resource reference: Editorial Commentary: 1, 2, 3 (Years)??…??and You're Out: The End of a 123-year Historic Era. Clin Infect Dis. 2016 May 01; 62(9):1089-91.
journal title abbreviation: Clin Infect Dis
publication date: 2016-02-02T00:00:00
year: 2016
type: Academic Article
type: Article
type: Document
type: Information Resource

Tuberculosis incidence in solid organ transplant recipients in Europe: A multicenter TBnet cohort study.
PubMed Identifier: 41429410
author list: Lange B, Brehm TT, Arend SM, Arias-Guillén M, Bakker M, Berastegui C, Babiker M, Charif R, Duarte R, Flick H, Hofland RW, Ismail J, Kniepeiss D, Krepel J, Krishnan N, Kuijpers DL, Kunst H, van Leth F, Lezaic V, Los-Arcos I, Machová J, Milburn H, Morais SA, Kon OM, Osoro-Suarez C, Pessegueiro Miranda H, Pesut D, Rahman A, Reischig T, Sánchez-Montalvá A, Spohn HE, Stegenga MT, de Vries APJ, Wagner D, Wobser R, Lange C, Sester M
published in: The Journal of infection
information resource reference: Tuberculosis incidence in solid organ transplant recipients in Europe: A multicenter TBnet cohort study. J Infect. 2026 Jan; 92(1):106668.
journal title abbreviation: J Infect
publication date: 2025-12-20T00:00:00
year: 2025
type: Academic Article
type: Article
type: Document
type: Information Resource

T-Cell Therapy: Options for Infectious Diseases.
PubMed Identifier: 26409284
author list: Parida SK, Poiret T, Zhenjiang L, Meng Q, Heyckendorf J, Lange C, Ambati AS, Rao MV, Valentini D, Ferrara G, Rangelova E, Dodoo E, Zumla A, Maeurer M
published in: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
information resource reference: T-Cell Therapy: Options for Infectious Diseases. Clin Infect Dis. 2015 Oct 15; 61Suppl 3:S217-24.
journal title abbreviation: Clin Infect Dis
publication date: 2015-10-15T00:00:00
year: 2015
type: Academic Article
type: Article
type: Document
type: Information Resource

Risk for latent and active tuberculosis in Germany.
PubMed Identifier: 27866367
author list: Herzmann C, Sotgiu G, Bellinger O, Diel R, Gerdes S, Goetsch U, Heykes-Uden H, Schaberg T, Lange C
published in: Infection
information resource reference: Risk for latent and active tuberculosis in Germany. Infection. 2017 Jun; 45(3):283-290.
journal title abbreviation: Infection
publication date: 2016-11-19T00:00:00
year: 2016
type: Academic Article
type: Article
type: Document
type: Information Resource

Serial measurements of transrenal mycobacterial DNA as indicators of the early bactericidal activity (EBA) of antituberculosis drugs.
PubMed Identifier: 28061950
author list: Heyckendorf J, Labugger I, van der Merwe L, Garcia-Basteiro AL, Diacon AH, Lange C
published in: Tuberculosis (Edinburgh, Scotland)
information resource reference: Serial measurements of transrenal mycobacterial DNA as indicators of the early bactericidal activity (EBA) of antituberculosis drugs. Tuberculosis (Edinb). 2017 01; 102:31-33.
journal title abbreviation: Tuberculosis (Edinb)
publication date: 2016-10-27T00:00:00
year: 2016
type: Academic Article
type: Article
type: Document
type: Information Resource

Tuberculosis Treatment Outcomes in Europe: Based on Treatment Completion, Not Cure.
PubMed Identifier: 28323453
author list: Dedicoat MJ, Günther G, Crudu V, Duarte R, Gualano G, Magis-Escurra C, Rumetshofer R, Skrahina A, Spinu V, Tiberi S, Viiklepp P, van Leth F, Lange C
published in: American journal of respiratory and critical care medicine
information resource reference: Tuberculosis Treatment Outcomes in Europe: Based on Treatment Completion, Not Cure. Am J Respir Crit Care Med. 2017 11 01; 196(9):1222-1224.
journal title abbreviation: Am J Respir Crit Care Med
publication date: 2017-11-01T00:00:00
year: 2017
type: Academic Article
type: Article
type: Document
type: Information Resource

Relapse-free cure from multidrug-resistant tuberculosis in Germany.
PubMed Identifier: 29467205
author list: Heyckendorf J, van Leth F, Kalsdorf B, Olaru ID, Günther G, Salzer HJF, Terhalle E, Rolling T, Glattki G, Müller M, Schuhmann M, Avsar K, Lange C
published in: The European respiratory journal
information resource reference: Relapse-free cure from multidrug-resistant tuberculosis in Germany. Eur Respir J. 2018 02; 51(2).
journal title abbreviation: Eur Respir J
publication date: 2018-02-21T00:00:00
year: 2018
type: Academic Article
type: Article
type: Document
type: Information Resource

Diagnosis and Management of Systemic Endemic Mycoses Causing Pulmonary Disease.
PubMed Identifier: 29953992
author list: Salzer HJF, Burchard G, Cornely OA, Lange C, Rolling T, Schmiedel S, Libman M, Capone D, Le T, Dalcolmo MP, Heyckendorf J
published in: Respiration; international review of thoracic diseases
information resource reference: Diagnosis and Management of Systemic Endemic Mycoses Causing Pulmonary Disease. Respiration. 2018; 96(3):283-301.
journal title abbreviation: Respiration
publication date: 2018-06-28T00:00:00
year: 2018
type: Academic Article
type: Article
type: Document
type: Information Resource

Intensive care unit patients with lower respiratory tract nosocomial infections: the ENIRRIs project.
PubMed Identifier: 29164144
author list: De Pascale G, Ranzani OT, Nseir S, Chastre J, Welte T, Antonelli M, Navalesi P, Garofalo E, Bruni A, Coelho LM, Skoczynski S, Longhini F, Taccone FS, Grimaldi D, Salzer HJF, Lange C, Froes F, Artigas A, Díaz E, Vallés J, Rodríguez A, Panigada M, Comellini V, Fasano L, Soave PM, Spinazzola G, Luyt CE, Alvarez-Lerma F, Marin J, Masclans JR, Chiumello D, Pezzi A, Schultz M, Mohamed H, Van Der Eerden M, Hoek RAS, Gommers DAMPJ, Pasquale MD, Civljak R, Kutleša M, Bassetti M, Dimopoulos G, Nava S, Rios F, Zampieri FG, Povoa P, Bos LD, Aliberti S, Torres A, Martín-Loeches I
published in: ERJ open research
information resource reference: Intensive care unit patients with lower respiratory tract nosocomial infections: the ENIRRIs project. ERJ Open Res. 2017 Oct; 3(4).
journal title abbreviation: ERJ Open Res
publication date: 2017-11-17T00:00:00
year: 2017
type: Academic Article
type: Article
type: Document
type: Information Resource

In reply.
PubMed Identifier: 27046728
author list: Merker M, Crudu V, Noroc E, Romancenco E, Chesov D, Günther G, Niemann S, Lange C
published in: The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease
information resource reference: In reply. Int J Tuberc Lung Dis. 2016 Mar; 20(3):424.
journal title abbreviation: Int J Tuberc Lung Dis
publication date: 2016-03-01T00:00:00
year: 2016
type: Academic Article
type: Article
type: Document
type: Information Resource

Chronic Cough and Severe Weight Loss in a 55-Year-Old Previously Healthy Man.
PubMed Identifier: 28931270
author list: Salzer HJF, Heyckendorf J, Kalsdorf B, Herzmann C, Hoffmann C, Lange C
published in: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
information resource reference: Chronic Cough and Severe Weight Loss in a 55-Year-Old Previously Healthy Man. Clin Infect Dis. 2017 07 15; 65(2):349-351.
journal title abbreviation: Clin Infect Dis
publication date: 2017-07-15T00:00:00
year: 2017
type: Academic Article
type: Article
type: Document
type: Information Resource

Burden and Characteristics of the Comorbidity Tuberculosis-Diabetes in Europe: TBnet Prevalence Survey and Case-Control Study.
PubMed Identifier: 30697572
author list: Sane Schepisi M, Navarra A, Altet Gomez MN, Dudnyk A, Dyrhol-Riise AM, Esteban J, Giorgetti PF, Gualano G, Guglielmetti L, Heyckendorf J, Kaluzhenina A, Lange B, Lange C, Manika K, Miah J, Nanovic Z, Pontali E, Prego MR, Solovic I, Tiberi S, Palmieri F, Girardi E
published in: Open forum infectious diseases
information resource reference: Burden and Characteristics of the Comorbidity Tuberculosis-Diabetes in Europe: TBnet Prevalence Survey and Case-Control Study. Open Forum Infect Dis. 2019 Jan; 6(1):ofy337.
journal title abbreviation: Open Forum Infect Dis
publication date: 2018-12-19T00:00:00
year: 2018
type: Academic Article
type: Article
type: Document
type: Information Resource

QT prolongation and cardiac toxicity of new tuberculosis drugs in Europe: a Tuberculosis Network European Trialsgroup (TBnet) study.
PubMed Identifier: 29880656
author list: Guglielmetti L, Tiberi S, Burman M, Kunst H, Wejse C, Togonidze T, Bothamley G, Lange C
published in: The European respiratory journal
information resource reference: QT prolongation and cardiac toxicity of new tuberculosis drugs in Europe: a Tuberculosis Network European Trialsgroup (TBnet) study. Eur Respir J. 2018 08; 52(2).
journal title abbreviation: Eur Respir J
publication date: 2018-08-16T00:00:00
year: 2018
type: Academic Article
type: Article
type: Document
type: Information Resource

Treatment of Chronic Pulmonary Aspergillosis: Current Standards and Future Perspectives.
PubMed Identifier: 29982245
author list: Alastruey-Izquierdo A, Cadranel J, Flick H, Godet C, Hennequin C, Hoenigl M, Kosmidis C, Lange C, Munteanu O, Page I, Salzer HJF
published in: Respiration; international review of thoracic diseases
information resource reference: Treatment of Chronic Pulmonary Aspergillosis: Current Standards and Future Perspectives. Respiration. 2018; 96(2):159-170.
journal title abbreviation: Respiration
publication date: 2018-07-06T00:00:00
year: 2018
type: Academic Article
type: Article
type: Document
type: Information Resource

Treatment of Nontuberculous Mycobacterial Pulmonary Disease: An Official ATS/ERS/ESCMID/IDSA Clinical Practice Guideline.
PubMed Identifier: 32628747
author list: Daley CL, Iaccarino JM, Lange C, Cambau E, Wallace RJ, Andrejak C, Böttger EC, Brozek J, Griffith DE, Guglielmetti L, Huitt GA, Knight SL, Leitman P, Marras TK, Olivier KN, Santin M, Stout JE, Tortoli E, van Ingen J, Wagner D, Winthrop KL
published in: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
information resource reference: Treatment of Nontuberculous Mycobacterial Pulmonary Disease: An Official ATS/ERS/ESCMID/IDSA Clinical Practice Guideline. Clin Infect Dis. 2020 08 14; 71(4):e1-e36.
journal title abbreviation: Clin Infect Dis
publication date: 2020-08-14T00:00:00
year: 2020
type: Academic Article
type: Article
type: Document
type: Information Resource

Treatment of nontuberculous mycobacterial pulmonary disease: an official ATS/ERS/ESCMID/IDSA clinical practice guideline.
PubMed Identifier: 32636299
author list: Daley CL, Iaccarino JM, Lange C, Cambau E, Wallace RJ, Andrejak C, Böttger EC, Brozek J, Griffith DE, Guglielmetti L, Huitt GA, Knight SL, Leitman P, Marras TK, Olivier KN, Santin M, Stout JE, Tortoli E, van Ingen J, Wagner D, Winthrop KL
published in: The European respiratory journal
information resource reference: Treatment of nontuberculous mycobacterial pulmonary disease: an official ATS/ERS/ESCMID/IDSA clinical practice guideline. Eur Respir J. 2020 07; 56(1).
journal title abbreviation: Eur Respir J
publication date: 2020-07-07T00:00:00
year: 2020
type: Academic Article
type: Article
type: Document
type: Information Resource

Reply to Dookie et al., "Whole-Genome Sequencing To Guide the Selection of Treatment for Drug-Resistant Tuberculosis".
PubMed Identifier: 30054377
author list: Köser CU, Heyckendorf J, Andres S, Olaru ID, Schön T, Sturegård E, Beckert P, Schleusener V, Kohl TA, Hillemann D, Moradigaravand D, Parkhill J, Peacock SJ, Niemann S, Lange C, Merker M
published in: Antimicrobial agents and chemotherapy
information resource reference: Reply to Dookie et al., "Whole-Genome Sequencing To Guide the Selection of Treatment for Drug-Resistant Tuberculosis". Antimicrob Agents Chemother. 2018 08; 62(8).
journal title abbreviation: Antimicrob Agents Chemother
publication date: 2018-07-27T00:00:00
year: 2018
type: Academic Article
type: Article
type: Document
type: Information Resource

Author Correction: Integrating standardized whole genome sequence analysis with a global Mycobacterium tuberculosis antibiotic resistance knowledgebase.
PubMed Identifier: 32081980
author list: Ezewudo M, Borens A, Chiner-Oms Á, Miotto P, Chindelevitch L, Starks AM, Hanna D, Liwski R, Zignol M, Gilpin C, Niemann S, Kohl TA, Warren RM, Crook D, Gagneux S, Hoffner S, Rodrigues C, Comas I, Engelthaler DM, Alland D, Rigouts L, Lange C, Dheda K, Hasan R, McNerney R, Cirillo DM, Schito M, Rodwell TC, Posey J
published in: Scientific reports
information resource reference: Author Correction: Integrating standardized whole genome sequence analysis with a global Mycobacterium tuberculosis antibiotic resistance knowledgebase. Sci Rep. 2020 Feb 21; 10(1):3531.
journal title abbreviation: Sci Rep
publication date: 2020-02-21T00:00:00
year: 2020
type: Academic Article
type: Article
type: Document
type: Information Resource

A comprehensive quality assessment framework for scientific events.
PubMed Identifier: 33169040
author list: Vahdati S, Fathalla S, Lange C, Behrend A, Say A, Say Z, Auer S
published in: Scientometrics
information resource reference: A comprehensive quality assessment framework for scientific events. Scientometrics. 2021; 126(1):641-682.
journal title abbreviation: Scientometrics
publication date: 2020-11-03T00:00:00
year: 2020
type: Academic Article
type: Article
type: Document
type: Information Resource

Sorry for the delay.
PubMed Identifier: 33823271
author list: Lange C, Chesov D, Konstantynovska O, Mandalakas AM, Udwadia Z
published in: Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases
information resource reference: Sorry for the delay. Clin Microbiol Infect. 2021 07; 27(7):941-943.
journal title abbreviation: Clin Microbiol Infect
publication date: 2021-04-03T00:00:00
year: 2021
type: Academic Article
type: Article
type: Document
type: Information Resource

Design of Multidrug-Resistant Tuberculosis Treatment Regimens Based on DNA Sequencing.
PubMed Identifier: 33900387
author list: Grobbel HP, Merker M, Köhler N, Andres S, Hoffmann H, Heyckendorf J, Reimann M, Barilar I, Dreyer V, Hillemann D, Kalsdorf B, Kohl TA, Sanchez Carballo P, Schaub D, Todt K, Utpatel C, Maurer FP, Lange C, Niemann S
published in: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
information resource reference: Design of Multidrug-Resistant Tuberculosis Treatment Regimens Based on DNA Sequencing. Clin Infect Dis. 2021 10 05; 73(7):1194-1202.
journal title abbreviation: Clin Infect Dis
publication date: 2021-10-05T00:00:00
year: 2021
type: Academic Article
type: Article
type: Document
type: Information Resource

Longitudinal Multi-omics Analyses Identify Responses of Megakaryocytes, Erythroid Cells, and Plasmablasts as Hallmarks of Severe COVID-19.
PubMed Identifier: 33296687
author list: Bernardes JP, Mishra N, Tran F, Bahmer T, Best L, Blase JI, Bordoni D, Franzenburg J, Geisen U, Josephs-Spaulding J, Köhler P, Künstner A, Rosati E, Aschenbrenner AC, Bacher P, Baran N, Boysen T, Brandt B, Bruse N, Dörr J, Dräger A, Elke G, Ellinghaus D, Fischer J, Forster M, Franke A, Franzenburg S, Frey N, Friedrichs A, Fuß J, Glück A, Hamm J, Hinrichsen F, Hoeppner MP, Imm S, Junker R, Kaiser S, Kan YH, Knoll R, Lange C, Laue G, Lier C, Lindner M, Marinos G, Markewitz R, Nattermann J, Noth R, Pickkers P, Rabe KF, Renz A, Röcken C, Rupp J, Schaffarzyk A, Scheffold A, Schulte-Schrepping J, Schunk D, Skowasch D, Ulas T, Wandinger KP, Wittig M, Zimmermann J, Busch H, Hoyer BF, Kaleta C, Heyckendorf J, Kox M, Rybniker J, Schreiber S, Schultze JL, Rosenstiel P
published in: Immunity
information resource reference: Longitudinal Multi-omics Analyses Identify Responses of Megakaryocytes, Erythroid Cells, and Plasmablasts as Hallmarks of Severe COVID-19. Immunity. 2020 12 15; 53(6):1296-1314.e9.
journal title abbreviation: Immunity
publication date: 2020-11-26T00:00:00
year: 2020
type: Academic Article
type: Article
type: Document
type: Information Resource

Management of drug-resistant tuberculosis.
PubMed Identifier: 31526739
author list: Lange C, Dheda K, Chesov D, Mandalakas AM, Udwadia Z, Horsburgh CR
published in: Lancet (London, England)
information resource reference: Management of drug-resistant tuberculosis. Lancet. 2019 09 14; 394(10202):953-966.
journal title abbreviation: Lancet
publication date: 2019-09-14T00:00:00
year: 2019
type: Academic Article
type: Article
type: Document
type: Information Resource

Seroprevalence of Aspergillus-Specific IgG Antibody among Mozambican Tuberculosis Patients.
PubMed Identifier: 34436134
author list: Salzer HJF, Massango I, Bhatt N, Machonisse E, Reimann M, Heldt S, Lange C, Hoelscher M, Khosa C, Rachow A
published in: Journal of fungi (Basel, Switzerland)
information resource reference: Seroprevalence of Aspergillus-Specific IgG Antibody among Mozambican Tuberculosis Patients. J Fungi (Basel). 2021 Jul 23; 7(8).
journal title abbreviation: J Fungi (Basel)
publication date: 2021-07-23T00:00:00
year: 2021
type: Academic Article
type: Article
type: Document
type: Information Resource

Tuberculosis prevention in children: a prospective community-based study in South Africa.
PubMed Identifier: 33122339
author list: Mandalakas AM, Hesseling AC, Kay A, Du Preez K, Martinez L, Ronge L, DiNardo A, Lange C, Kirchner HL
published in: The European respiratory journal
information resource reference: Tuberculosis prevention in children: a prospective community-based study in South Africa. Eur Respir J. 2021 04; 57(4).
journal title abbreviation: Eur Respir J
publication date: 2021-04-22T00:00:00
year: 2021
type: Academic Article
type: Article
type: Document
type: Information Resource

WNT6/ACC2-induced storage of triacylglycerols in macrophages is exploited by Mycobacterium tuberculosis.
PubMed Identifier: 34255743
author list: Brandenburg J, Marwitz S, Tazoll SC, Waldow F, Kalsdorf B, Vierbuchen T, Scholzen T, Gross A, Goldenbaum S, Hölscher A, Hein M, Linnemann L, Reimann M, Kispert A, Leitges M, Rupp J, Lange C, Niemann S, Behrends J, Goldmann T, Heine H, Schaible UE, Hölscher C, Schwudke D, Reiling N
published in: The Journal of clinical investigation
information resource reference: WNT6/ACC2-induced storage of triacylglycerols in macrophages is exploited by Mycobacterium tuberculosis. J Clin Invest. 2021 08 16; 131(16).
journal title abbreviation: J Clin Invest
publication date: 2021-08-16T00:00:00
year: 2021
type: Academic Article
type: Article
type: Document
type: Information Resource

Treatment outcome definitions in chronic pulmonary aspergillosis: a CPAnet consensus statement.
PubMed Identifier: 35236726
author list: Van Braeckel E, Page I, Davidsen JR, Laursen CB, Agarwal R, Alastruey-Izquierdo A, Barac A, Cadranel J, Chakrabarti A, Cornely OA, Denning DW, Flick H, Gangneux JP, Godet C, Hayashi Y, Hennequin C, Hoenigl M, Irfan M, Izumikawa K, Koh WJ, Kosmidis C, Lange C, Lamprecht B, Laurent F, Munteanu O, Oladele R, Patterson TF, Watanabe A, Salzer HJF
published in: The European respiratory journal
information resource reference: Treatment outcome definitions in chronic pulmonary aspergillosis: a CPAnet consensus statement. Eur Respir J. 2022 06; 59(6).
journal title abbreviation: Eur Respir J
publication date: 2022-06-09T00:00:00
year: 2022
type: Academic Article
type: Article
type: Document
type: Information Resource

Prediction of anti-tuberculosis treatment duration based on a 22-gene transcriptomic model.
PubMed Identifier: 33574078
author list: Heyckendorf J, Marwitz S, Reimann M, Avsar K, DiNardo AR, Günther G, Hoelscher M, Ibraim E, Kalsdorf B, Kaufmann SHE, Kontsevaya I, van Leth F, Mandalakas AM, Maurer FP, Müller M, Nitschkowski D, Olaru ID, Popa C, Rachow A, Rolling T, Rybniker J, Salzer HJF, Sanchez-Carballo P, Schuhmann M, Schaub D, Spinu V, Suárez I, Terhalle E, Unnewehr M, Weiner J, Goldmann T, Lange C
published in: The European respiratory journal
information resource reference: Prediction of anti-tuberculosis treatment duration based on a 22-gene transcriptomic model. Eur Respir J. 2021 09; 58(3).
journal title abbreviation: Eur Respir J
publication date: 2021-09-02T00:00:00
year: 2021
type: Academic Article
type: Article
type: Document
type: Information Resource

100 years of Mycobacterium bovis bacille Calmette-Guérin.
PubMed Identifier: 34506734
author list: Lange C, Aaby P, Behr MA, Donald PR, Kaufmann SHE, Netea MG, Mandalakas AM
published in: The Lancet. Infectious diseases
information resource reference: 100 years of Mycobacterium bovis bacille Calmette-Guérin. Lancet Infect Dis. 2022 01; 22(1):e2-e12.
journal title abbreviation: Lancet Infect Dis
publication date: 2021-09-07T00:00:00
year: 2021
type: Academic Article
type: Article
type: Document
type: Information Resource

War in Ukraine: an immense threat to the fight against tuberculosis.
PubMed Identifier: 35450921
author list: Dahl V, Migliori GB, Lange C, Wejse C
published in: The European respiratory journal
information resource reference: War in Ukraine: an immense threat to the fight against tuberculosis. Eur Respir J. 2022 04; 59(4).
journal title abbreviation: Eur Respir J
publication date: 2022-04-21T00:00:00
year: 2022
type: Academic Article
type: Article
type: Document
type: Information Resource

Mycobacterial infections in adults with haematological malignancies and haematopoietic stem cell transplants: guidelines from the 8th European Conference on Infections in Leukaemia.
PubMed Identifier: 35636446
author list: Bergeron A, Mikulska M, De Greef J, Bondeelle L, Franquet T, Herrmann JL, Lange C, Spriet I, Akova M, Donnelly JP, Maertens J, Maschmeyer G, Rovira M, Goletti D, de la Camara R
published in: The Lancet. Infectious diseases
information resource reference: Mycobacterial infections in adults with haematological malignancies and haematopoietic stem cell transplants: guidelines from the 8th European Conference on Infections in Leukaemia. Lancet Infect Dis. 2022 12; 22(12):e359-e369.
journal title abbreviation: Lancet Infect Dis
publication date: 2022-05-27T00:00:00
year: 2022
type: Academic Article
type: Article
type: Document
type: Information Resource

A revolution in the management of multidrug-resistant tuberculosis.
PubMed Identifier: 36368335
author list: Dheda K, Lange C
published in: Lancet (London, England)
information resource reference: A revolution in the management of multidrug-resistant tuberculosis. Lancet. 2022 11 26; 400(10366):1823-1825.
journal title abbreviation: Lancet
publication date: 2022-11-08T00:00:00
year: 2022
type: Academic Article
type: Article
type: Document
type: Information Resource

Co-administration of treatment for rifampicin-resistant TB and chronic HCV infection: A TBnet and ESGMYC study.
PubMed Identifier: 35271917
author list: Tunesi S, Dû DL, Gualano G, Millet JP, Skrahin A, Bothamley G, Casas X, Goletti D, Lange C, Musso M, Palmieri F, Pourcher V, Rioux C, Skrahina A, Veziris N, Viatushka D, Jachym-Fréchet M, Guglielmetti L
published in: The Journal of infection
information resource reference: Co-administration of treatment for rifampicin-resistant TB and chronic HCV infection: A TBnet and ESGMYC study. J Infect. 2022 06; 84(6):834-872.
journal title abbreviation: J Infect
publication date: 2022-03-07T00:00:00
year: 2022
type: Academic Article
type: Article
type: Document
type: Information Resource

Correction: Rapid molecular diagnostics of tuberculosis resistance by targeted stool sequencing.
PubMed Identifier: 36127736
author list: Sibandze DB, Kay A, Dreyer V, Sikhondze W, Dlamini Q, DiNardo A, Mtetwa G, Lukhele B, Vambe D, Lange C, Dlamini MG, Ness T, Mejia R, Kalsdorf B, Heyckendorf J, Kuhns M, Maurer FP, Dlamini S, Maphalala G, Niemann S, Mandalakas A
published in: Genome medicine
information resource reference: Correction: Rapid molecular diagnostics of tuberculosis resistance by targeted stool sequencing. Genome Med. 2022 Sep 20; 14(1):107.
journal title abbreviation: Genome Med
publication date: 2022-09-20T00:00:00
year: 2022
type: Academic Article
type: Article
type: Document
type: Information Resource

Tuberculosis endotypes to guide stratified host-directed therapy.
PubMed Identifier: 34693385
author list: DiNardo AR, Nishiguchi T, Grimm SL, Schlesinger LS, Graviss EA, Cirillo JD, Coarfa C, Mandalakas AM, Heyckendorf J, Kaufmann SHE, Lange C, Netea MG, Van Crevel R
published in: Med (New York, N.Y.)
information resource reference: Tuberculosis endotypes to guide stratified host-directed therapy. Med. 2021 03 12; 2(3):217-232.
journal title abbreviation: Med
publication date: 2021-01-16T00:00:00
year: 2021
type: Academic Article
type: Article
type: Document
type: Information Resource

Pathogenesis of tuberculosis: the 1930 Lübeck disaster revisited.
PubMed Identifier: 35768133
author list: Donald P, Kaufmann S, Thee S, Mandalakas AM, Lange C
published in: European respiratory review : an official journal of the European Respiratory Society
information resource reference: Pathogenesis of tuberculosis: the 1930 Lübeck disaster revisited. Eur Respir Rev. 2022 Jun 30; 31(164).
journal title abbreviation: Eur Respir Rev
publication date: 2022-06-28T00:00:00
year: 2022
type: Academic Article
type: Article
type: Document
type: Information Resource

Implementing molecular tuberculosis diagnostic methods in limited-resource and high-burden countries.
PubMed Identifier: 36865933
author list: Vasiliu A, Saktiawati AMI, Duarte R, Lange C, Cirillo DM
published in: Breathe (Sheffield, England)
information resource reference: Implementing molecular tuberculosis diagnostic methods in limited-resource and high-burden countries. Breathe (Sheff). 2022 Dec; 18(4):220226.
journal title abbreviation: Breathe (Sheff)
publication date: 2023-02-14T00:00:00
year: 2023
type: Academic Article
type: Article
type: Document
type: Information Resource

Emerging bedaquiline-resistant tuberculosis.
PubMed Identifier: 37931639
author list: Lange C, Vasiliu A, Mandalakas AM
published in: The Lancet. Microbe
information resource reference: Emerging bedaquiline-resistant tuberculosis. Lancet Microbe. 2023 12; 4(12):e964-e965.
journal title abbreviation: Lancet Microbe
publication date: 2023-11-03T00:00:00
year: 2023
type: Academic Article
type: Article
type: Document
type: Information Resource

Tuberculosis screening in migrants to the EU/EEA and UK.
PubMed Identifier: 37918879
author list: Köhler N, Vasiliu A, Mandalakas AM, Martinez L, Lange C
published in: The European respiratory journal
information resource reference: Tuberculosis screening in migrants to the EU/EEA and UK. Eur Respir J. 2023 11; 62(5).
journal title abbreviation: Eur Respir J
publication date: 2023-11-02T00:00:00
year: 2023
type: Academic Article
type: Article
type: Document
type: Information Resource

Bedaquiline: what might the future hold?
PubMed Identifier: 39074472
author list: Shaw ES, Stoker NG, Potter JL, Claassen H, Leslie A, Tweed CD, Chiang CY, Conradie F, Esmail H, Lange C, Pinto L, Rucsineanu O, Sloan DJ, Theron G, Tisile P, Voo TC, Warren RM, Lebina L, Lipman M
published in: The Lancet. Microbe
information resource reference: Bedaquiline: what might the future hold? Lancet Microbe. 2024 12; 5(12):100909.
journal title abbreviation: Lancet Microbe
publication date: 2024-07-27T00:00:00
year: 2024
type: Academic Article
type: Article
type: Document
type: Information Resource

Carl Flügge, one of the last holistic hygienists and discoverer of droplet transmission of infectious diseases.
PubMed Identifier: 39093331
author list: Donald PR, Kaufmann SHE, Schaub D, Thee S, Lange C
published in: Medical microbiology and immunology
information resource reference: Carl Flügge, one of the last holistic hygienists and discoverer of droplet transmission of infectious diseases. Med Microbiol Immunol. 2024 Aug 02; 213(1):17.
journal title abbreviation: Med Microbiol Immunol
publication date: 2024-08-02T00:00:00
year: 2024
type: Academic Article
type: Article
type: Document
type: Information Resource

Availability and costs of medicines for the treatment of tuberculosis in Europe.
PubMed Identifier: 35961488
author list: Günther G, Guglielmetti L, Leu C, Lange C, van Leth F
published in: Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases
information resource reference: Availability and costs of medicines for the treatment of tuberculosis in Europe. Clin Microbiol Infect. 2023 Jan; 29(1):77-84.
journal title abbreviation: Clin Microbiol Infect
publication date: 2022-08-10T00:00:00
year: 2022
type: Academic Article
type: Article
type: Document
type: Information Resource

Activin A levels are raised during human tuberculosis and blockade of the activin signaling axis influences murine responses to M. tuberculosis infection.
PubMed Identifier: 38376260
author list: Nieuwenhuizen NE, Nouailles G, Sutherland JS, Zyla J, Pasternack AH, Heyckendorf J, Frye BC, Höhne K, Zedler U, Bandermann S, Abu Abed U, Brinkmann V, Gutbier B, Witzenrath M, Suttorp N, Zissel G, Lange C, Ritvos O, Kaufmann SHE
published in: mBio
information resource reference: Activin A levels are raised during human tuberculosis and blockade of the activin signaling axis influences murine responses to M. tuberculosis infection. mBio. 2024 Mar 13; 15(3):e0340823.
journal title abbreviation: mBio
publication date: 2024-02-20T00:00:00
year: 2024
type: Academic Article
type: Article
type: Document
type: Information Resource

Recent advances in the treatment of tuberculosis.
PubMed Identifier: 37482332
author list: Motta I, Boeree M, Chesov D, Dheda K, Günther G, Horsburgh CR, Kherabi Y, Lange C, Lienhardt C, McIlleron HM, Paton NI, Stagg HR, Thwaites G, Udwadia Z, Van Crevel R, Velásquez GE, Wilkinson RJ, Guglielmetti L
published in: Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases
information resource reference: Recent advances in the treatment of tuberculosis. Clin Microbiol Infect. 2024 Sep; 30(9):1107-1114.
journal title abbreviation: Clin Microbiol Infect
publication date: 2023-07-22T00:00:00
year: 2023
type: Academic Article
type: Article
type: Document
type: Information Resource

A first-in-class leucyl-tRNA synthetase inhibitor, ganfeborole, for rifampicin-susceptible tuberculosis: a phase 2a open-label, randomized trial.
PubMed Identifier: 38365949
author list: Diacon AH, Barry CE, Carlton A, Chen RY, Davies M, de Jager V, Fletcher K, Koh GCKW, Kontsevaya I, Heyckendorf J, Lange C, Reimann M, Penman SL, Scott R, Maher-Edwards G, Tiberi S, Vlasakakis G, Upton CM, Aguirre DB
published in: Nature medicine
information resource reference: A first-in-class leucyl-tRNA synthetase inhibitor, ganfeborole, for rifampicin-susceptible tuberculosis: a phase 2a open-label, randomized trial. Nat Med. 2024 03; 30(3):896-904.
journal title abbreviation: Nat Med
publication date: 2024-02-16T00:00:00
year: 2024
type: Academic Article
type: Article
type: Document
type: Information Resource

Availability of drugs and resistance testing for bedaquiline, pretomanid, linezolid, and moxifloxacin (BPaL(M)) regimen for rifampicin-resistant tuberculosis in Europe.
PubMed Identifier: 38490355
author list: Günther G, Guglielmetti L, Kherabi Y, Duarte R, Lange C
published in: Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases
information resource reference: Availability of drugs and resistance testing for bedaquiline, pretomanid, linezolid, and moxifloxacin (BPaL(M)) regimen for rifampicin-resistant tuberculosis in Europe. Clin Microbiol Infect. 2024 Sep; 30(9):1197.e1-1197.e4.
journal title abbreviation: Clin Microbiol Infect
publication date: 2024-03-13T00:00:00
year: 2024
type: Academic Article
type: Article
type: Document
type: Information Resource

Performance of a stool-based quantitative PCR assay for the diagnosis of tuberculosis in adolescents and adults: a multinational, prospective diagnostic accuracy study.
PubMed Identifier: 38461830
author list: Kay A, Vasiliu A, Carratala-Castro L, Mtafya B, Mendez Reyes JE, Maphalala N, Munguambe S, Mulengwa D, Ness T, Saavedra B, Bacha J, Maphalala G, Mejia R, Mtetwa G, Acacio S, Manjate P, Mambuque E, Shiba N, Kota N, Ziyane M, Ntinginya NE, Lange C, Kirchner HL, DiNardo AR, Garcia-Basteiro AL, Mandalakas AM
published in: The Lancet. Microbe
information resource reference: Performance of a stool-based quantitative PCR assay for the diagnosis of tuberculosis in adolescents and adults: a multinational, prospective diagnostic accuracy study. Lancet Microbe. 2024 05; 5(5):e433-e441.
journal title abbreviation: Lancet Microbe
publication date: 2024-03-07T00:00:00
year: 2024
type: Academic Article
type: Article
type: Document
type: Information Resource

Global treatment outcomes of extensively drug-resistant tuberculosis in adults: A systematic review and meta-analysis.
PubMed Identifier: 37356629
author list: Pedersen OS, Holmgaard FB, Mikkelsen MKD, Lange C, Sotgiu G, Lillebaek T, Andersen AB, Wejse CM, Dahl VN
published in: The Journal of infection
information resource reference: Global treatment outcomes of extensively drug-resistant tuberculosis in adults: A systematic review and meta-analysis. J Infect. 2023 09; 87(3):177-189.
journal title abbreviation: J Infect
publication date: 2023-06-23T00:00:00
year: 2023
type: Academic Article
type: Article
type: Document
type: Information Resource

Chronic Pulmonary Aspergillosis as a Considerable Complication in Post-Tuberculosis Lung Disease.
PubMed Identifier: 38196060
author list: Neuböck MJ, Günther G, Barac A, Davidsen JR, Laursen CB, Agarwal R, Sehgal IS, Lange C, Salzer HJF
published in: Seminars in respiratory and critical care medicine
information resource reference: Chronic Pulmonary Aspergillosis as a Considerable Complication in Post-Tuberculosis Lung Disease. Semin Respir Crit Care Med. 2024 02; 45(1):102-113.
journal title abbreviation: Semin Respir Crit Care Med
publication date: 2024-01-09T00:00:00
year: 2024
type: Academic Article
type: Article
type: Document
type: Information Resource

Clinical spectrum and relevance of Mycobacterium malmoense: Systematic review and meta-analysis of 859 patients.
PubMed Identifier: 38906266
author list: Wetzstein N, Dahl VN, Lillebaek T, Lange C
published in: The Journal of infection
information resource reference: Clinical spectrum and relevance of Mycobacterium malmoense: Systematic review and meta-analysis of 859 patients. J Infect. 2024 Aug; 89(2):106203.
journal title abbreviation: J Infect
publication date: 2024-06-19T00:00:00
year: 2024
type: Academic Article
type: Article
type: Document
type: Information Resource

High risk of drug-resistant tuberculosis in IGRA-negative contacts: should preventive treatment be considered?
PubMed Identifier: 39836352
author list: Brehm TT, Köhler N, Grobbel HP, Welling J, Mandalakas AM, Fava V, Schurr E, Lange C
published in: Infection
information resource reference: High risk of drug-resistant tuberculosis in IGRA-negative contacts: should preventive treatment be considered? Infection. 2025 Aug; 53(4):1501-1506.
journal title abbreviation: Infection
publication date: 2025-01-21T00:00:00
year: 2025
type: Academic Article
type: Article
type: Document
type: Information Resource

Rapid Diagnosis of Recurrent Paucibacillary Tuberculosis.
PubMed Identifier: 37207169
author list: Jafari C, Olaru ID, Daduna F, Lange C, Kalsdorf B
published in: Pathogens & immunity
information resource reference: Rapid Diagnosis of Recurrent Paucibacillary Tuberculosis. Pathog Immun. 2022; 7(2):189-202.
journal title abbreviation: Pathog Immun
publication date: 2023-04-19T00:00:00
year: 2023
type: Academic Article
type: Article
type: Document
type: Information Resource

Whispers in the Wind: Face Mask Sampling for Mycobacterium tuberculosis Detection in Children With Pulmonary Tuberculosis.
PubMed Identifier: 38798080
author list: Meiwes L, Kontsevaya I, Chesov D, Kulcitkaia S, Dreyer V, Hillemann D, Dlamini Q, Williams C, Barer M, Brinkmann F, Krüger R, Thee S, Kay A, Mandalakas AM, Lange C
published in: The Journal of infectious diseases
information resource reference: Whispers in the Wind: Face Mask Sampling for Mycobacterium tuberculosis Detection in Children With Pulmonary Tuberculosis. J Infect Dis. 2024 Dec 16; 230(6):1510-1517.
journal title abbreviation: J Infect Dis
publication date: 2024-12-16T00:00:00
year: 2024
type: Academic Article
type: Article
type: Document
type: Information Resource

Post-tuberculosis lung impairment: systematic review and meta-analysis of spirometry data from 14?621 people.
PubMed Identifier: 37076175
author list: Ivanova O, Hoffmann VS, Lange C, Hoelscher M, Rachow A
published in: European respiratory review : an official journal of the European Respiratory Society
information resource reference: Post-tuberculosis lung impairment: systematic review and meta-analysis of spirometry data from 14?621 people. Eur Respir Rev. 2023 Jun 30; 32(168).
journal title abbreviation: Eur Respir Rev
publication date: 2023-04-19T00:00:00
year: 2023
type: Academic Article
type: Article
type: Document
type: Information Resource

https://connects.catalyst.harvard.edu/Profiles/profile/323033975
PubMed Identifier: 38734022
author list: Martinez L, Seddon JA, Horsburgh CR, Lange C, Mandalakas AM
published in: The Lancet. Respiratory medicine
information resource reference: Effectiveness of preventive treatment among different age groups and Mycobacterium tuberculosis infection status: a systematic review and individual-participant data meta-analysis of contact tracing studies. Lancet Respir Med. 2024 08; 12(8):633-641.
journal title abbreviation: Lancet Respir Med
publication date: 2024-05-08T00:00:00
year: 2024
type: Academic Article
type: Article
type: Document
type: Information Resource
label: Effectiveness of preventive treatment among different age groups and Mycobacterium tuberculosis infection status: a systematic review and individual-participant data meta-analysis of contact tracing studies.

Rolling out new anti-tuberculosis drugs without diagnostic capacity.
PubMed Identifier: 37492347
author list: Ness T, Van LH, Petermane I, Duarte R, Lange C, Menzies D, Cirillo DM
published in: Breathe (Sheffield, England)
information resource reference: Rolling out new anti-tuberculosis drugs without diagnostic capacity. Breathe (Sheff). 2023 Jun; 19(2):230084.
journal title abbreviation: Breathe (Sheff)
publication date: 2023-07-11T00:00:00
year: 2023
type: Academic Article
type: Article
type: Document
type: Information Resource

Aspergillus-specific IgG antibodies for diagnosing chronic pulmonary aspergillosis compared with the reference standard-author's reply.
PubMed Identifier: 38365116
author list: Salzer HJF, Lange C
published in: Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases
information resource reference: Aspergillus-specific IgG antibodies for diagnosing chronic pulmonary aspergillosis compared with the reference standard-author's reply. Clin Microbiol Infect. 2024 May; 30(5):696-697.
journal title abbreviation: Clin Microbiol Infect
publication date: 2024-02-14T00:00:00
year: 2024
type: Academic Article
type: Article
type: Document
type: Information Resource

Impact of Mycobacterium tuberculosis strain type on multidrug-resistant tuberculosis severity, Republic of Moldova.
PubMed Identifier: 37827458
author list: Chesov E, Chesov D, Reimann M, Dreyer V, Utpatel C, Gröschel MI, Ciobanu N, Crudu V, Lange C, Heyckendorf J, Merker M
published in: The Journal of infection
information resource reference: Impact of Mycobacterium tuberculosis strain type on multidrug-resistant tuberculosis severity, Republic of Moldova. J Infect. 2023 12; 87(6):588-591.
journal title abbreviation: J Infect
publication date: 2023-10-10T00:00:00
year: 2023
type: Academic Article
type: Article
type: Document
type: Information Resource

Tuberculosis incidence in foreign-born people residing in European countries in 2020.
PubMed Identifier: 37855907
author list: Vasiliu A, Köhler N, Altpeter E, Ægisdóttir TR, Amerali M, de Oñate WA, Bakos Á, D'Amato S, Cirillo DM, van Crevel R, Davidaviciene E, Demuth I, Domínguez J, Duarte R, Günther G, Guthmann JP, Hatzianastasiou S, Holm LH, Herrador Z, Hribar U, Huberty C, Ibraim E, Jackson S, Jensenius M, Josefsdottir KS, Koch A, Korzeniewska-Kosela M, Kuksa L, Kunst H, Lienhardt C, Mahler B, Makek MJ, Muylle I, Normark J, Pace-Asciak A, Petrovic G, Pieridou D, Russo G, Rzhepishevska O, Salzer HJF, Marques MS, Schmid D, Solovic I, Sukholytka M, Svetina P, Tyufekchieva M, Vasankari T, Viiklepp P, Villand K, Wallenfels J, Wesolowski S, Mandalakas AM, Martinez L, Zenner D, Lange C
published in: Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin
information resource reference: Tuberculosis incidence in foreign-born people residing in European countries in 2020. Euro Surveill. 2023 10; 28(42).
journal title abbreviation: Euro Surveill
publication date: 2023-10-01T00:00:00
year: 2023
type: Academic Article
type: Article
type: Document
type: Information Resource

Aspergillus-specific IgG antibodies for diagnosing chronic pulmonary aspergillosis compared to the reference standard.
PubMed Identifier: 37689265
author list: Salzer HJF, Reimann M, Oertel C, Davidsen JR, Laursen CB, Van Braeckel E, Agarwal R, Avsar K, Munteanu O, Irfan M, Lange C
published in: Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases
information resource reference: Aspergillus-specific IgG antibodies for diagnosing chronic pulmonary aspergillosis compared to the reference standard. Clin Microbiol Infect. 2023 Dec; 29(12):1605.e1-1605.e4.
journal title abbreviation: Clin Microbiol Infect
publication date: 2023-09-07T00:00:00
year: 2023
type: Academic Article
type: Article
type: Document
type: Information Resource

Impact of drug-resistant tuberculosis on socio-economic status, quality of life and psychological well-being of patients in Bucharest, Romania: a prospective cohort study.
PubMed Identifier: 39710755
author list: Ramachandran R, Dumitrescu A, Baiceanu D, Popa C, Dragomir A, Mahler B, Hoelscher M, Lange C, Heyckendorf J, Rachow A, Ibraim E, Ivanova O
published in: Journal of health, population, and nutrition
information resource reference: Impact of drug-resistant tuberculosis on socio-economic status, quality of life and psychological well-being of patients in Bucharest, Romania: a prospective cohort study. J Health Popul Nutr. 2024 12 22; 43(1):223.
journal title abbreviation: J Health Popul Nutr
publication date: 2024-12-22T00:00:00
year: 2024
type: Academic Article
type: Article
type: Document
type: Information Resource

(Re-)introduction of TNF antagonists and JAK inhibitors in patients with previous tuberculosis: a systematic review.
PubMed Identifier: 38663653
author list: Brehm TT, Reimann M, Köhler N, Lange C
published in: Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases
information resource reference: (Re-)introduction of TNF antagonists and JAK inhibitors in patients with previous tuberculosis: a systematic review. Clin Microbiol Infect. 2024 Aug; 30(8):989-998.
journal title abbreviation: Clin Microbiol Infect
publication date: 2024-04-23T00:00:00
year: 2024
type: Academic Article
type: Article
type: Document
type: Information Resource

Rapid Diagnostic Sequencing of Stool DNA Using Targeted Nanopore Sequencing in Patients With a Pulmonary Tuberculosis Diagnosis.
PubMed Identifier: 40212033
author list: Ness T, Maphalala N, Khumalo W, Sibandze D, Seeger A, Madison M, Vasiliu A, Mulengwa D, Gascua C, Ziyane M, Dlamini S, Maphalala G, Bortz E, Kay A, Lange C, Dreyer V, Niemann T, Niemann S, DiNardo A, Mandalakas A
published in: Open forum infectious diseases
information resource reference: Rapid Diagnostic Sequencing of Stool DNA Using Targeted Nanopore Sequencing in Patients With a Pulmonary Tuberculosis Diagnosis. Open Forum Infect Dis. 2025 Apr; 12(4):ofaf121.
journal title abbreviation: Open Forum Infect Dis
publication date: 2025-03-06T00:00:00
year: 2025
type: Academic Article
type: Article
type: Document
type: Information Resource

Developing biomarker assays to accelerate tuberculosis drug development: defining target product profiles.
PubMed Identifier: 38735303
author list: Gillespie SH, DiNardo AR, Georghiou SB, Sabiiti W, Kohli M, Panzner U, Kontsevaya I, Hittel N, Stuyver LJ, Tan JB, van Crevel R, Lange C, Thuong TNT, Heyckendorf J, Ruhwald M, Heinrich N
published in: The Lancet. Microbe
information resource reference: Developing biomarker assays to accelerate tuberculosis drug development: defining target product profiles. Lancet Microbe. 2024 09; 5(9):100869.
journal title abbreviation: Lancet Microbe
publication date: 2024-05-09T00:00:00
year: 2024
type: Academic Article
type: Article
type: Document
type: Information Resource

The molecular bacterial load assay predicts treatment responses in patients with pre-XDR/XDR-tuberculosis more accurately than GeneXpert Ultra MTB/Rif.
PubMed Identifier: 39733827
author list: Neumann M, Reimann M, Chesov D, Popa C, Dragomir A, Popescu O, Munteanu R, Hölscher A, Honeyborne I, Heyckendorf J, Lange C, Hölscher C, Kalsdorf B
published in: The Journal of infection
information resource reference: The molecular bacterial load assay predicts treatment responses in patients with pre-XDR/XDR-tuberculosis more accurately than GeneXpert Ultra MTB/Rif. J Infect. 2025 Feb; 90(2):106399.
journal title abbreviation: J Infect
publication date: 2024-12-27T00:00:00
year: 2024
type: Academic Article
type: Article
type: Document
type: Information Resource

The importance of getting the dose right in the treatment of tuberculosis.
PubMed Identifier: 40104255
author list: Dudnyk A, Lutchmun W, Duarte R, Lange C, Svensson EM
published in: Breathe (Sheffield, England)
information resource reference: The importance of getting the dose right in the treatment of tuberculosis. Breathe (Sheff). 2025 Jan; 21(1):240177.
journal title abbreviation: Breathe (Sheff)
publication date: 2025-03-18T00:00:00
year: 2025
type: Academic Article
type: Article
type: Document
type: Information Resource

A Year in Review on Tuberculosis and Non-tuberculous Mycobacteria Disease: A 2025 Update for Clinicians and Scientists.
PubMed Identifier: 40062355
author list: Lange C, Bothamley G, Günther G, Guglielmetti L, Kontsevaya I, Kuksa L, Lange B, Lorent N, Saluzzo F, Sester M, Tebruegge M, Tunesi S, Tweed C
published in: Pathogens & immunity
information resource reference: A Year in Review on Tuberculosis and Non-tuberculous Mycobacteria Disease: A 2025 Update for Clinicians and Scientists. Pathog Immun. 2025; 10(2):1-45.
journal title abbreviation: Pathog Immun
publication date: 2025-03-02T00:00:00
year: 2025
type: Academic Article
type: Article
type: Document
type: Information Resource

Uncovering Ethnicity-Specific Recessive Loci for Alzheimer's Disease in 89 Dominican Families Using Family-Based WGS Analysis.
PubMed Identifier: 40488219
author list: Lee S, Hecker J, Vardarajan BN, Kelly RS, Prince N, Mullin K, Lutz SM, Hahn G, Lasky-Su J, Mayeux RP, Tanzi RE, Lange C, Prokopenko D
published in: Genetic epidemiology
information resource reference: Uncovering Ethnicity-Specific Recessive Loci for Alzheimer's Disease in 89 Dominican Families Using Family-Based WGS Analysis. Genet Epidemiol. 2025 Jul; 49(5):e70014.
journal title abbreviation: Genet Epidemiol
publication date: 2025-07-01T00:00:00
year: 2025
type: Academic Article
type: Article
type: Document
type: Information Resource

A successful UN High-Level Meeting on antimicrobial resistance must build on the 2023 UN High-Level Meeting on tuberculosis.
PubMed Identifier: 39030054
author list: Cirillo D, Anthony R, Gagneux S, Horsburgh CR, Hasan R, Darboe S, Laniado-Laborin R, Probandari A, Tukvadze N, Arcêncio RA, Bimba JS, Brighenti S, Chesov D, Chiang CY, Kalmambetova G, Knight G, Konstantynovska O, Kruse A, Lange C, Mayanja-Kizza H, McBryde E, Min J, Sanchez-Montalva A, Sulis G, Tsogt B, Van Der Walt M, Yeboah-Manu D, Hauser J
published in: The Lancet. Global health
information resource reference: A successful UN High-Level Meeting on antimicrobial resistance must build on the 2023 UN High-Level Meeting on tuberculosis. Lancet Glob Health. 2024 08; 12(8):e1225-e1226.
journal title abbreviation: Lancet Glob Health
publication date: 2024-08-01T00:00:00
year: 2024
type: Academic Article
type: Article
type: Document
type: Information Resource

Inclusion of patient-centered, non-microbiological endpoints and biomarkers in tuberculosis drug trials.
PubMed Identifier: 40475250
author list: DiNardo AR, Sabiiti W, Gillespie SH, Georghiou SB, Heinrich N, Hittel N, Taghlabi S, Carrero Longlax D, Kohli M, Panzner U, Musia C, Lange C, Vasiliu A, Arts RJW, Mandalakas AM, Ruhwald M, Stuyver LJ, van Crevel R
published in: Frontiers in antibiotics
information resource reference: Inclusion of patient-centered, non-microbiological endpoints and biomarkers in tuberculosis drug trials. Front Antibiot. 2025; 4:1570989.
journal title abbreviation: Front Antibiot
publication date: 2025-05-22T00:00:00
year: 2025
type: Academic Article
type: Article
type: Document
type: Information Resource

Safety of high dose bedaquiline treatment in patients with extensively drug-resistant tuberculosis.
PubMed Identifier: 41198387
author list: Peterka M, Krieger D, Khatamzas E, Denkinger CM, Köhler N, Lange C, Macholz M, Lübbert C, Daller S, Knappik M, Kuhns M, Häcker B, Polsfuß S, Bauer T, Otto-Knapp R
published in: The European respiratory journal
information resource reference: Safety of high dose bedaquiline treatment in patients with extensively drug-resistant tuberculosis. Eur Respir J. 2026 Jan; 67(1).
journal title abbreviation: Eur Respir J
publication date: 2026-01-08T00:00:00
year: 2026
type: Academic Article
type: Article
type: Document
type: Information Resource

A calcium-sensing receptor allelic series and underdiagnosis of genetically driven hypocalcemia.
PubMed Identifier: 40664210
author list: Chang JB, Barnhill CP, Apostolov AM, Soliai MM, Hecker J, Nierenberg JL, Stapleton Smith LM, Mathew AS, Zeng X, Diao J, Fernando CD, Chen Q, Dulken BW, Petukhov A, Altman R, Josephs TM, Lasky-Su JA, Gorvin CM, Roberts MS, Adler SH, Fox JC, Lange C, Ji SG
published in: American journal of human genetics
information resource reference: A calcium-sensing receptor allelic series and underdiagnosis of genetically driven hypocalcemia. Am J Hum Genet. 2025 Aug 07; 112(8):1818-1832.
journal title abbreviation: Am J Hum Genet
publication date: 2025-07-14T00:00:00
year: 2025
type: Academic Article
type: Article
type: Document
type: Information Resource

Corrigendum to "Candidate anti-tuberculosis medicines and regimens under clinical evaluation" [Clin Microbiol Infect 30(9) (2024) 1131-1138].
PubMed Identifier: 41067498
author list: Hoelscher M, Barros-Aguirre D, Dara M, Heinrich N, Sun E, Lange C, Tiberi S, Wells C
published in: Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases
information resource reference: Corrigendum to "Candidate anti-tuberculosis medicines and regimens under clinical evaluation" [Clin Microbiol Infect 30(9) (2024) 1131-1138]. Clin Microbiol Infect. 2026 Jan; 32(1):199.
journal title abbreviation: Clin Microbiol Infect
publication date: 2025-10-09T00:00:00
year: 2025
type: Academic Article
type: Article
type: Document
type: Information Resource

Treatment outcomes of extensively drug-resistant tuberculosis in Europe: a retrospective cohort study.
PubMed Identifier: 40697337
author list: Kherabi Y, Skouvig Pedersen O, Lange C, Bénézit F, Chesov D, Codecasa LR, Dudnyk A, Kiria N, Konstantynovska O, Marigot-Outtandy D, Panciu TC, Poignon C, Sasi S, Schaub D, Solodovnikova V, Vasiliauskaitè L, Yeghiazaryan L, Günther G, Guglielmetti L
published in: The Lancet regional health. Europe
information resource reference: Treatment outcomes of extensively drug-resistant tuberculosis in Europe: a retrospective cohort study. Lancet Reg Health Eur. 2025 Sep; 56:101380.
journal title abbreviation: Lancet Reg Health Eur
publication date: 2025-07-15T00:00:00
year: 2025
type: Academic Article
type: Article
type: Document
type: Information Resource

A multinational Delphi consensus on tuberculosis screening of migrants in Europe.
PubMed Identifier: 41438856
author list: Pinheiro M, Aguiar A, Moreira DN, Akkerman OW, Al-Suwaidi Z, Alffenaar JC, Arandjelovic I, Brito U, de Colombani P, Curcic R, Garcia-Basteiro AL, Goletti D, Günther G, Ibraim E, Kapata N, Lange C, Lipman M, Jankovic Makek M, Marais BJ, Mariandyshev A, Magis-Escurra C, Migliori GB, Sánchez Montalvá A, Nanovic Z, Palmero DJ, Priwitzer M, Raviglione MCB, Silva DR, Salzer HJF, Schwarzbach C, Spruijt I, Winthrop KL, Udwadia Z, Vasankari T, Vilaplana C, Duarte R
published in: ERJ open research
information resource reference: A multinational Delphi consensus on tuberculosis screening of migrants in Europe. ERJ Open Res. 2025 Nov; 11(6).
journal title abbreviation: ERJ Open Res
publication date: 2025-12-22T00:00:00
year: 2025
type: Academic Article
type: Article
type: Document
type: Information Resource

At the crossroads of infection and malignancy: the challenge of tuberculosis in migrating populations - Case Report and Epidemiologic Analysis.
PubMed Identifier: 41436966
author list: Epple HJ, Domaszewska T, Brünneck AV, Furth C, Dommerich S, Lange C, Schöning DV, Maschmeyer G, Bös L, Schwartz S, Schneider T, Mathas S
published in: BMC infectious diseases
information resource reference: At the crossroads of infection and malignancy: the challenge of tuberculosis in migrating populations - Case Report and Epidemiologic Analysis. BMC Infect Dis. 2025 Dec 23; 26(1):145.
journal title abbreviation: BMC Infect Dis
publication date: 2025-12-23T00:00:00
year: 2025
type: Academic Article
type: Article
type: Document
type: Information Resource

Mycobacterium florentinum pulmonary disease: a case report and review of the literature.
PubMed Identifier: 41408185
author list: Leo F, Polsfuss S, Przewosnik AS, Grohé C, Lange C
published in: BMC infectious diseases
information resource reference: Mycobacterium florentinum pulmonary disease: a case report and review of the literature. BMC Infect Dis. 2025 Dec 17; 26(1):103.
journal title abbreviation: BMC Infect Dis
publication date: 2025-12-17T00:00:00
year: 2025
type: Academic Article
type: Article
type: Document
type: Information Resource

Consensus on the management of refractory nontuberculous mycobacterial pulmonary disease.
PubMed Identifier: 41198394
author list: Moreira-Sousa D, Martins B, Aguiar A, Pinheiro M, Akkerman O, Aksamit TR, Aliberti S, Andrejak C, Daley CL, van Ingen J, Lange C, Lipman M, Loebinger MR, Jankovic Makek M, Morimoto K, Thomson RM, Wagner D, Winthrop KL, Yim JJ, Duarte R
published in: The European respiratory journal
information resource reference: Consensus on the management of refractory nontuberculous mycobacterial pulmonary disease. Eur Respir J. 2026 Jan; 67(1).
journal title abbreviation: Eur Respir J
publication date: 2026-01-08T00:00:00
year: 2026
type: Academic Article
type: Article
type: Document
type: Information Resource

Analyzing associations and higher-order effects in multi-omics data with double machine learning.
PubMed Identifier: 41427345
author list: Hecker J, Prokopenko D, Hahn G, Lee S, Lutz SM, Lange C
published in: bioRxiv : the preprint server for biology
information resource reference: Analyzing associations and higher-order effects in multi-omics data with double machine learning. bioRxiv. 2025 Dec 08.
journal title abbreviation: bioRxiv
publication date: 2025-12-08T00:00:00
year: 2025
type: Academic Article
type: Article
type: Document
type: Information Resource

Management of adverse events in TB care and active TB drug safety monitoring.
PubMed Identifier: 41607631
author list: Ma'aruf SY, Sharma A, Fox S, Duarte R, Lange C, Tiberi S
published in: Breathe (Sheffield, England)
information resource reference: Management of adverse events in TB care and active TB drug safety monitoring. Breathe (Sheff). 2026 Jan; 22(1):250203.
journal title abbreviation: Breathe (Sheff)
publication date: 2026-01-27T00:00:00
year: 2026
type: Academic Article
type: Article
type: Document
type: Information Resource

Enhancing tuberculosis care in lower and middle-income countries through digital adherence technologies.
PubMed Identifier: 41710455
author list: Ahmad R, Ramos JP, Duarte R, Lange C, Van Rest J
published in: Breathe (Sheffield, England)
information resource reference: Enhancing tuberculosis care in lower and middle-income countries through digital adherence technologies. Breathe (Sheff). 2026 Jan; 22(1):250173.
journal title abbreviation: Breathe (Sheff)
publication date: 2026-02-17T00:00:00
year: 2026
type: Academic Article
type: Article
type: Document
type: Information Resource

Host- and pathogen-related determinants of pulmonary versus extrapulmonary tuberculosis.
PubMed Identifier: 41605541
author list: Tulu B, Brehm TT, van Crevel R, Dallenga T, DiNardo AR, Dheda K, Eggeling J, Enbiale W, Gröschel MI, Hao J, Kumar V, van Laarhoven A, Londt R, Prosser G, Randall P, Reiling N, Rybniker J, Schaible UE, Schurr E, Suarez I, Theobald SJ, Wilkinson RJ, Lange C
published in: European respiratory review : an official journal of the European Respiratory Society
information resource reference: Host- and pathogen-related determinants of pulmonary versus extrapulmonary tuberculosis. Eur Respir Rev. 2026 01; 35(179).
journal title abbreviation: Eur Respir Rev
publication date: 2026-01-28T00:00:00
year: 2026
type: Academic Article
type: Article
type: Document
type: Information Resource

Noninvasive diagnosis of pulmonary tuberculosis using face mask sampling: a prospective study in adults.
PubMed Identifier: 41475487
author list: Woelk D, Meiwes L, Ciobanu N, Crudu V, Comanac AM, Kulcitkaia S, Vasiliu A, Mandalakas AM, Lange C, Brehm TT, Chesov D
published in: Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases
information resource reference: Noninvasive diagnosis of pulmonary tuberculosis using face mask sampling: a prospective study in adults. Clin Microbiol Infect. 2026 Apr; 32(4):644-649.
journal title abbreviation: Clin Microbiol Infect
publication date: 2025-12-29T00:00:00
year: 2025
type: Academic Article
type: Article
type: Document
type: Information Resource

Management of nontuberculous mycobacterial Pulmonary disease refractory to guideline-based therapy: A systematic review.
PubMed Identifier: 41733158
author list: Moreira-Sousa D, Martins B, Aguiar A, Pinheiro M, Akkerman OW, Aksamit TR, Aliberti S, Andrejak C, Daley CL, van Ingen J, Lange C, Lipman M, Loebinger MR, Jankovic Makek M, Morimoto K, Thomson R, Wagner D, Winthrop KL, Yim JJ, Duarte R
published in: Pulmonology
information resource reference: Management of nontuberculous mycobacterial Pulmonary disease refractory to guideline-based therapy: A systematic review. Pulmonology. 2026 Dec; 32(1):2632467.
journal title abbreviation: Pulmonology
publication date: 2026-02-24T00:00:00
year: 2026
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 737682
type: Authorship
author rank in publication: 15
linked author: Lange, Christoph
linked information resource: Nonsyndromic cleft lip with or without cleft palate: Increased burden of rare variants within Gremlin-1, a component of the bone morphogenetic protein 4 pathway.

Nonsyndromic cleft lip with or without cleft palate: Increased burden of rare variants within Gremlin-1, a component of the bone morphogenetic protein 4 pathway.
PubMed Identifier: 24706492
author list: Al Chawa T, Ludwig KU, Fier H, Pötzsch B, Reich RH, Schmidt G, Braumann B, Daratsianos N, Böhmer AC, Schuencke H, Alblas M, Fricker N, Hoffmann P, Knapp M, Lange C, Nöthen MM, Mangold E
published in: Birth defects research. Part A, Clinical and molecular teratology
information resource reference: Nonsyndromic cleft lip with or without cleft palate: Increased burden of rare variants within Gremlin-1, a component of the bone morphogenetic protein 4 pathway. Birth Defects Res A Clin Mol Teratol. 2014 Jun; 100(6):493-8.
journal title abbreviation: Birth Defects Res A Clin Mol Teratol
publication date: 2014-04-07T00:00:00
year: 2014
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 171445
type: Authorship
author rank in publication: 17
linked author: Lange, Christoph
linked information resource: IL1B polymorphisms modulate cystic fibrosis lung disease.

Authorship 351745
type: Authorship
author rank in publication: 3
linked author: Lange, Christoph
linked information resource: A Bayesian approach to genetic association studies with family-based designs.

Authorship 436184
type: Authorship
author rank in publication: 30
linked author: Lange, Christoph
linked information resource: Combined analysis from eleven linkage studies of bipolar disorder provides strong evidence of susceptibility loci on chromosomes 6q and 8q.

Authorship 33177
type: Authorship
author rank in publication: 5
linked author: Lange, Christoph
linked information resource: On the meta-analysis of genome-wide association studies: a robust and efficient approach to combine population and family-based studies.

Senior Lecturer on Biostatistics
is primary position: true
position in department: Biostatistics
position in division: https://connects.catalyst.harvard.edu/Profiles/profile/1229413
sort order: 1
type: Position
HR job title: Senior Lecturer on Biostatistics
position in organization: Harvard T.H. Chan School of Public Health

Assistant Professor of Medicine
is primary position: true
position in department: Medicine
position in division: Pulmonary
sort order: 1
type: Position
HR job title: Assistant Professor of Medicine
position in organization: Brigham and Women's Hospital

Professor of Biostatistics
is primary position: true
position in department: Biostatistics
position in division: https://connects.catalyst.harvard.edu/Profiles/profile/1229413
sort order: 1
type: Position
HR job title: Professor of Biostatistics
position in organization: Harvard T.H. Chan School of Public Health

Ronda Stryker and William Johnston Professor of Global Health
is primary position: true
position in department: Global Health and Social Medicine
position in division: https://connects.catalyst.harvard.edu/Profiles/profile/1229413
sort order: 1
type: Position
HR job title: Ronda Stryker and William Johnston Professor of Global Health
position in organization: Harvard Medical School

Adjunct Professor of Nutrition
is primary position: true
position in department: Nutrition
position in division: https://connects.catalyst.harvard.edu/Profiles/profile/1229413
sort order: 1
type: Position
HR job title: Adjunct Professor of Nutrition
position in organization: Harvard T.H. Chan School of Public Health

Assistant Professor of Medicine
position in department: Medicine
position in division: Channing Division of Network Medicine
sort order: 2
type: Position
HR job title: Assistant Professor of Medicine
position in organization: Brigham and Women's Hospital

Mary B. Saltonstall Professor of Ethics and Population Health, Emeritus
is primary position: true
position in department: Global Health and Population
position in division: https://connects.catalyst.harvard.edu/Profiles/profile/1229413
sort order: 1
type: Position
HR job title: Mary B. Saltonstall Professor of Ethics and Population Health, Emeritus
position in organization: Harvard T.H. Chan School of Public Health

Professor of Medicine
is primary position: true
position in department: Medicine
position in division: Channing Division of Network Medicine
sort order: 1
type: Position
HR job title: Professor of Medicine
position in organization: Brigham and Women's Hospital

Harvey V. Fineberg Professor of Public Health, Emerita
is primary position: true
position in department: Biostatistics
position in division: https://connects.catalyst.harvard.edu/Profiles/profile/1229413
sort order: 1
type: Position
HR job title: Harvey V. Fineberg Professor of Public Health, Emerita
position in organization: Harvard T.H. Chan School of Public Health

Associate Professor of Global Health
is primary position: true
position in department: Global Health and Population
position in division: https://connects.catalyst.harvard.edu/Profiles/profile/1229413
sort order: 1
type: Position
HR job title: Associate Professor of Global Health
position in organization: Harvard T.H. Chan School of Public Health

Senior Lecturer on Biostatistics
is primary position: true
position in department: Biostatistics
position in division: https://connects.catalyst.harvard.edu/Profiles/profile/1229413
sort order: 1
type: Position
HR job title: Senior Lecturer on Biostatistics
position in organization: Harvard T.H. Chan School of Public Health

Professor of Biostatistics
is primary position: true
position in department: Biostatistics
position in division: https://connects.catalyst.harvard.edu/Profiles/profile/1229413
sort order: 1
type: Position
HR job title: Professor of Biostatistics
position in organization: Harvard T.H. Chan School of Public Health

Associate Professor of Population Medicine
is primary position: true
position in department: Population Medicine
position in division: https://connects.catalyst.harvard.edu/Profiles/profile/1229413
sort order: 1
type: Position
HR job title: Associate Professor of Population Medicine
position in organization: Harvard Pilgrim Healthcare

Authorship 343726
type: Authorship
author rank in publication: 4
linked author: Lange, Christoph
linked information resource: Chromosome 12q harbors multiple genetic loci related to asthma and asthma-related phenotypes.

Authorship 750109
type: Authorship
author rank in publication: 3
linked author: Lange, Christoph
linked information resource: An alternative hypothesis testing strategy for secondary phenotype data in case-control genetic association studies.

An alternative hypothesis testing strategy for secondary phenotype data in case-control genetic association studies.
PubMed Identifier: 25071819
author list: Lutz SM, Hokanson JE, Lange C
published in: Frontiers in genetics
information resource reference: An alternative hypothesis testing strategy for secondary phenotype data in case-control genetic association studies. Front Genet. 2014; 5:188.
journal title abbreviation: Front Genet
publication date: 2014-07-01T00:00:00
year: 2014
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 507939
type: Authorship
author rank in publication: 62
linked author: Lange, Christoph
linked information resource: Meta-analysis of the INSIG2 association with obesity including 74,345 individuals: does heterogeneity of estimates relate to study design?

The rare TREM2 R47H variant exerts only a modest effect on Alzheimer disease risk.
PubMed Identifier: 25186855
author list: Hooli BV, Parrado AR, Mullin K, Yip WK, Liu T, Roehr JT, Qiao D, Jessen F, Peters O, Becker T, Ramirez A, Lange C, Bertram L, Tanzi RE
published in: Neurology
information resource reference: The rare TREM2 R47H variant exerts only a modest effect on Alzheimer disease risk. Neurology. 2014 Oct 07; 83(15):1353-8.
journal title abbreviation: Neurology
publication date: 2014-09-03T00:00:00
year: 2014
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 375380
type: Authorship
author rank in publication: 4
linked author: Lange, Christoph
linked information resource: On the parsing of statistical information in family-based association testing.

Authorship 762253
type: Authorship
author rank in publication: 12
linked author: Lange, Christoph
linked information resource: The rare TREM2 R47H variant exerts only a modest effect on Alzheimer disease risk.

Authorship 762623
type: Authorship
author rank in publication: 5
linked author: Lange, Christoph
linked information resource: The Wingless homolog WNT5A and its receptor Frizzled-5 regulate inflammatory responses of human mononuclear cells induced by microbial stimulation.

The Wingless homolog WNT5A and its receptor Frizzled-5 regulate inflammatory responses of human mononuclear cells induced by microbial stimulation.
PubMed Identifier: 16601243
author list: Blumenthal A, Ehlers S, Lauber J, Buer J, Lange C, Goldmann T, Heine H, Brandt E, Reiling N
published in: Blood
information resource reference: The Wingless homolog WNT5A and its receptor Frizzled-5 regulate inflammatory responses of human mononuclear cells induced by microbial stimulation. Blood. 2006 Aug 01; 108(3):965-73.
journal title abbreviation: Blood
publication date: 2006-04-06T00:00:00
year: 2006
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 405000
type: Authorship
author rank in publication: 4
linked author: Lange, Christoph
linked information resource: FBAT-SNP-PC: an approach for multiple markers and single trait in family-based association tests.

Authorship 407103
type: Authorship
author rank in publication: 16
linked author: Lange, Christoph
linked information resource: MMP12, lung function, and COPD in high-risk populations.

Authorship 767990
type: Authorship
author rank in publication: 27
linked author: Lange, Christoph
linked information resource: Common genetic variants associated with resting oxygenation in chronic obstructive pulmonary disease.

Authorship 768194
type: Authorship
author rank in publication: 5
linked author: Lange, Christoph
linked information resource: FARVAT: a family-based rare variant association test.

FARVAT: a family-based rare variant association test.
PubMed Identifier: 25075118
author list: Choi S, Lee S, Cichon S, Nöthen MM, Lange C, Park T, Won S
published in: Bioinformatics (Oxford, England)
information resource reference: FARVAT: a family-based rare variant association test. Bioinformatics. 2014 Nov 15; 30(22):3197-205.
journal title abbreviation: Bioinformatics
publication date: 2014-07-29T00:00:00
year: 2014
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 769151
type: Authorship
author rank in publication: 4
linked author: Lange, Christoph
linked information resource: Attitudes about tuberculosis prevention in the elimination phase: a survey among physicians in Germany.

Attitudes about tuberculosis prevention in the elimination phase: a survey among physicians in Germany.
PubMed Identifier: 25393241
author list: Gutsfeld C, Olaru ID, Vollrath O, Lange C
published in: PloS one
information resource reference: Attitudes about tuberculosis prevention in the elimination phase: a survey among physicians in Germany. PLoS One. 2014; 9(11):e112681.
journal title abbreviation: PLoS One
publication date: 2014-11-13T00:00:00
year: 2014
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 770217
type: Authorship
author rank in publication: 6
linked author: Lange, Christoph
linked information resource: A novel method for detecting association between DNA methylation and diseases using spatial information.

A novel method for detecting association between DNA methylation and diseases using spatial information.
PubMed Identifier: 25250875
author list: Yip WK, Fier H, DeMeo DL, Aryee M, Laird N, Lange C
published in: Genetic epidemiology
information resource reference: A novel method for detecting association between DNA methylation and diseases using spatial information. Genet Epidemiol. 2014 Dec; 38(8):714-21.
journal title abbreviation: Genet Epidemiol
publication date: 2014-09-22T00:00:00
year: 2014
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 248338
type: Authorship
author rank in publication: 11
linked author: Lange, Christoph
linked information resource: A genome-wide association study of COPD identifies a susceptibility locus on chromosome 19q13.

Authorship 367276
type: Authorship
author rank in publication: 7
linked author: Lange, Christoph
linked information resource: Evidence for an association of the dopamine D5 receptor gene on age at onset of attention deficit hyperactivity disorder.

Authorship 771164
type: Authorship
author rank in publication: 2
linked author: Lange, Christoph
linked information resource: A general framework for robust and efficient association analysis in family-based designs: quantitative and dichotomous phenotypes.

A general framework for robust and efficient association analysis in family-based designs: quantitative and dichotomous phenotypes.
PubMed Identifier: 23740776
author list: Won S, Lange C
published in: Statistics in medicine
information resource reference: A general framework for robust and efficient association analysis in family-based designs: quantitative and dichotomous phenotypes. Stat Med. 2013 Nov 10; 32(25):4482-98.
journal title abbreviation: Stat Med
publication date: 2013-06-06T00:00:00
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type: Academic Article
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type: Information Resource

Menzies, Nicolas
eCommons Login: NAM13
first name: Nicolas
last name: Menzies
full name: Nicolas Alan Menzies, Ph.D.
has faculty rank: Associate Professor
photo: https://connects.catalyst.harvard.edu/Profiles/profile/Modules/CustomViewPersonGeneralInfo/PhotoHandler.ashx
Person ID: 81994
person in primary position: Associate Professor of Global Health
type: Agent
type: Person
preferred title: Associate Professor of Global Health

Authorship 54716
type: Authorship
author rank in publication: 1
linked author: Lange, Christoph
linked information resource: Power and design considerations for a general class of family-based association tests: quantitative traits.

Authorship 2650
type: Authorship
author rank in publication: 2
linked author: Lange, Christoph
linked information resource: Family-based association analysis of a statistically derived quantitative traits for ADHD reveal an association in DRD4 with inattentive symptoms in ADHD individuals.

Authorship 28061
type: Authorship
author rank in publication: 8
linked author: Lange, Christoph
linked information resource: Assessment of Alzheimer's disease case-control associations using family-based methods.

Authorship 315224
type: Authorship
author rank in publication: 13
linked author: Lange, Christoph
linked information resource: On genome-wide association studies for family-based designs: an integrative analysis approach combining ascertained family samples with unselected controls.

Authorship 539942
type: Authorship
author rank in publication: 3
linked author: Lange, Christoph
linked information resource: Handling the data management needs of high-throughput sequencing data: SpeedGene, a compression algorithm for the efficient storage of genetic data.

Authorship 561333
type: Authorship
author rank in publication: 3
linked author: Lange, Christoph
linked information resource: Genome-wide linkage of forced mid-expiratory flow in chronic obstructive pulmonary disease.

PLD3 gene variants and Alzheimer's disease.
PubMed Identifier: 25832413
author list: Hooli BV, Lill CM, Mullin K, Qiao D, Lange C, Bertram L, Tanzi RE
published in: Nature
information resource reference: PLD3 gene variants and Alzheimer's disease. Nature. 2015 Apr 02; 520(7545):E7-8.
journal title abbreviation: Nature
publication date: 2015-04-02T00:00:00
year: 2015
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 468251
type: Authorship
author rank in publication: 1
linked author: Lange, Christoph
linked information resource: On a general class of conditional tests for family-based association studies in genetics: the asymptotic distribution, the conditional power, and optimality considerations.

Authorship 44586
type: Authorship
author rank in publication: 2
linked author: Lange, Christoph
linked information resource: Extended haplotype in the tumor necrosis factor gene cluster is associated with asthma and asthma-related phenotypes.

Authorship 443006
type: Authorship
author rank in publication: 3
linked author: Lange, Christoph
linked information resource: Genetic association analysis of copy-number variation (CNV) in human disease pathogenesis.

Authorship 459297
type: Authorship
author rank in publication: 7
linked author: Lange, Christoph
linked information resource: Genomewide association between GLCCI1 and response to glucocorticoid therapy in asthma.

Authorship 514017
type: Authorship
author rank in publication: 3
linked author: Lange, Christoph
linked information resource: Exploring candidate gene associations with neuropsychological performance.

Authorship 517026
type: Authorship
author rank in publication: 2
linked author: Lange, Christoph
linked information resource: New powerful approaches for family-based association tests with longitudinal measurements.

Authorship 569800
type: Authorship
author rank in publication: 2
linked author: Lange, Christoph
linked information resource: Family-based methods for linkage and association analysis.

Authorship 228339
type: Authorship
author rank in publication: 22
linked author: Lange, Christoph
linked information resource: A common genetic variant is associated with adult and childhood obesity.

Authorship 228517
type: Authorship
author rank in publication: 18
linked author: Lange, Christoph
linked information resource: Bronchoalveolar lavage enzyme-linked immunospot for a rapid diagnosis of tuberculosis: a Tuberculosis Network European Trialsgroup study.

Authorship 73829
type: Authorship
author rank in publication: 8
linked author: Lange, Christoph
linked information resource: HIV-1 infection impairs the bronchoalveolar T-cell response to mycobacteria.

Authorship 249180
type: Authorship
author rank in publication: 2
linked author: Lange, Christoph
linked information resource: Gene-environment interaction tests for dichotomous traits in trios and sibships.

Authorship 25131
type: Authorship
author rank in publication: 11
linked author: Lange, Christoph
linked information resource: Polymorphisms in IL13, total IgE, eosinophilia, and asthma exacerbations in childhood.

Authorship 543157
type: Authorship
author rank in publication: 3
linked author: Lange, Christoph
linked information resource: Two-stage testing strategies for genome-wide association studies in family-based designs.

Authorship 497207
type: Authorship
author rank in publication: 5
linked author: Lange, Christoph
linked information resource: Family-based association between Alzheimer's disease and variants in UBQLN1.

Authorship 565986
type: Authorship
author rank in publication: 1
linked author: Lange, Christoph
linked information resource: Power calculations for a general class of family-based association tests: dichotomous traits.

Authorship 274659
type: Authorship
author rank in publication: 10
linked author: Lange, Christoph
linked information resource: Natriuretic peptide system gene variants are associated with ventricular dysfunction after coronary artery bypass grafting.

Authorship 272501
type: Authorship
author rank in publication: 12
linked author: Lange, Christoph
linked information resource: Potential role for IL-2 ELISpot in differentiating recent and remote infection in tuberculosis contact tracing.

Authorship 246789
type: Authorship
author rank in publication: 1
linked author: Lange, Christoph
linked information resource: A multivariate family-based association test using generalized estimating equations: FBAT-GEE.

Authorship 42405
type: Authorship
author rank in publication: 3
linked author: Lange, Christoph
linked information resource: Common genetic variation in the GAD1 gene and the entire family of DLX homeobox genes and autism spectrum disorders.

Authorship 331490
type: Authorship
author rank in publication: 3
linked author: Lange, Christoph
linked information resource: A doubly robust test for gene-environment interaction in family-based studies of affected offspring.

Authorship 34406
type: Authorship
author rank in publication: 6
linked author: Lange, Christoph
linked information resource: https://connects.catalyst.harvard.edu/Profiles/profile/892063

Authorship 188915
type: Authorship
author rank in publication: 1
linked author: Lange, Christoph
linked information resource: Family-based association tests for survival and times-to-onset analysis.

Authorship 273705
type: Authorship
author rank in publication: 5
linked author: Lange, Christoph
linked information resource: Association of vitamin D receptor gene polymorphisms with childhood and adult asthma.

Authorship 328973
type: Authorship
author rank in publication: 6
linked author: Lange, Christoph
linked information resource: Development of a Pharmacogenetic Predictive Test in asthma: proof of concept.

Authorship 379307
type: Authorship
author rank in publication: 40
linked author: Lange, Christoph
linked information resource: The association of a SNP upstream of INSIG2 with body mass index is reproduced in several but not all cohorts.

Authorship 127347
type: Authorship
author rank in publication: 2
linked author: Lange, Christoph
linked information resource: The IL12B gene is associated with asthma.

Authorship 74711
type: Authorship
author rank in publication: 1
linked author: Lange, Christoph
linked information resource: Mapping quantitative trait Loci using generalized estimating equations.

Authorship 89673
type: Authorship
author rank in publication: 2
linked author: Lange, Christoph
linked information resource: Differentiating population stratification from genotyping error using family data.

Authorship 89993
type: Authorship
author rank in publication: 8
linked author: Lange, Christoph
linked information resource: On the adjustment for covariates in genetic association analysis: a novel, simple principle to infer direct causal effects.

Authorship 319308
type: Authorship
author rank in publication: 7
linked author: Lange, Christoph
linked information resource: Comparison of linkage and association strategies for quantitative traits using the COGA dataset.

Authorship 328398
type: Authorship
author rank in publication: 5
linked author: Lange, Christoph
linked information resource: Paternal history of asthma and airway responsiveness in children with asthma.

Authorship 37677
type: Authorship
author rank in publication: 10
linked author: Lange, Christoph
linked information resource: Stronger evidence for replication of NPPA using genome-wide genotyping data.

Authorship 377981
type: Authorship
author rank in publication: 3
linked author: Lange, Christoph
linked information resource: Testing for non-random mating: evidence for ancestry-related assortative mating in the Framingham heart study.

Authorship 238979
type: Authorship
author rank in publication: 22
linked author: Lange, Christoph
linked information resource: Resequencing of VAX1 in patients with nonsyndromic cleft lip with or without cleft palate.

Authorship 441958
type: Authorship
author rank in publication: 4
linked author: Lange, Christoph
linked information resource: Impact of population stratification on family-based association tests with longitudinal measurements.

Authorship 160527
type: Authorship
author rank in publication: 6
linked author: Lange, Christoph
linked information resource: Is it rare or common?

Genetic control of gene expression at novel and established chronic obstructive pulmonary disease loci.
PubMed Identifier: 25315895
author list: Castaldi PJ, Cho MH, Zhou X, Qiu W, Mcgeachie M, Celli B, Bakke P, Gulsvik A, Lomas DA, Crapo JD, Beaty TH, Rennard S, Harshfield B, Lange C, Singh D, Tal-Singer R, Riley JH, Quackenbush J, Raby BA, Carey VJ, Silverman EK, Hersh CP
published in: Human molecular genetics
information resource reference: Genetic control of gene expression at novel and established chronic obstructive pulmonary disease loci. Hum Mol Genet. 2015 Feb 15; 24(4):1200-10.
journal title abbreviation: Hum Mol Genet
publication date: 2014-10-14T00:00:00
year: 2014
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 369442
type: Authorship
author rank in publication: 8
linked author: Lange, Christoph
linked information resource: On the analysis of copy-number variations in genome-wide association studies: a translation of the family-based association test.

Authorship 479043
type: Authorship
author rank in publication: 9
linked author: Lange, Christoph
linked information resource: Comprehensive testing of positionally cloned asthma genes in two populations.

Authorship 801115
type: Authorship
author rank in publication: 5
linked author: Lange, Christoph
linked information resource: PLD3 gene variants and Alzheimer's disease.

Authorship 786674
type: Authorship
author rank in publication: 9
linked author: Lange, Christoph
linked information resource: Beyond GWAS in COPD: probing the landscape between gene-set associations, genome-wide associations and protein-protein interaction networks.

Authorship 787441
type: Authorship
author rank in publication: 10
linked author: Lange, Christoph
linked information resource: Role of common and rare APP DNA sequence variants in Alzheimer disease.

Authorship 786203
type: Authorship
author rank in publication: 9
linked author: Lange, Christoph
linked information resource: Relationship between chemokine receptor expression, chemokine levels and HIV-1 replication in the lungs of persons exposed to Mycobacterium tuberculosis.

Authorship 788135
type: Authorship
author rank in publication: 28
linked author: Lange, Christoph
linked information resource: Genome-wide association study in obsessive-compulsive disorder: results from the OCGAS.

Authorship 793929
type: Authorship
author rank in publication: 19
linked author: Lange, Christoph
linked information resource: A genome-wide association study of bronchodilator response in asthmatics.

Authorship 796048
type: Authorship
author rank in publication: 14
linked author: Lange, Christoph
linked information resource: Genetic control of gene expression at novel and established chronic obstructive pulmonary disease loci.

Authorship 786253
type: Authorship
author rank in publication: 6
linked author: Lange, Christoph
linked information resource: HLA-DQ strikes again: genome-wide association study further confirms HLA-DQ in the diagnosis of asthma among adults.

Authorship 788878
type: Authorship
author rank in publication: 7
linked author: Lange, Christoph
linked information resource: Rare autosomal copy number variations in early-onset familial Alzheimer's disease.

Genome-wide association study in obsessive-compulsive disorder: results from the OCGAS.
PubMed Identifier: 24821223
author list: Mattheisen M, Samuels JF, Wang Y, Greenberg BD, Fyer AJ, McCracken JT, Geller DA, Murphy DL, Knowles JA, Grados MA, Riddle MA, Rasmussen SA, McLaughlin NC, Nurmi EL, Askland KD, Qin HD, Cullen BA, Piacentini J, Pauls DL, Bienvenu OJ, Stewart SE, Liang KY, Goes FS, Maher B, Pulver AE, Shugart YY, Valle D, Lange C, Nestadt G
published in: Molecular psychiatry
information resource reference: Genome-wide association study in obsessive-compulsive disorder: results from the OCGAS. Mol Psychiatry. 2015 Mar; 20(3):337-44.
journal title abbreviation: Mol Psychiatry
publication date: 2014-05-13T00:00:00
year: 2014
type: Academic Article
type: Article
type: Document
type: Information Resource

Relationship between chemokine receptor expression, chemokine levels and HIV-1 replication in the lungs of persons exposed to Mycobacterium tuberculosis.
PubMed Identifier: 23147374
author list: Kalsdorf B, Skolimowska KH, Scriba TJ, Dawson R, Dheda K, Wood K, Hofmeister J, Hanekom WA, Lange C, Wilkinson RJ
published in: European journal of immunology
information resource reference: Relationship between chemokine receptor expression, chemokine levels and HIV-1 replication in the lungs of persons exposed to Mycobacterium tuberculosis. Eur J Immunol. 2013 Feb; 43(2):540-9.
journal title abbreviation: Eur J Immunol
publication date: 2012-12-13T00:00:00
year: 2012
type: Academic Article
type: Article
type: Document
type: Information Resource

Beyond GWAS in COPD: probing the landscape between gene-set associations, genome-wide associations and protein-protein interaction networks.
PubMed Identifier: 25171373
author list: McDonald ML, Mattheisen M, Cho MH, Liu YY, Harshfield B, Hersh CP, Bakke P, Gulsvik A, Lange C, Beaty TH, Silverman EK
published in: Human heredity
information resource reference: Beyond GWAS in COPD: probing the landscape between gene-set associations, genome-wide associations and protein-protein interaction networks. Hum Hered. 2014; 78(3-4):131-9.
journal title abbreviation: Hum Hered
publication date: 2014-08-27T00:00:00
year: 2014
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 351126
type: Authorship
author rank in publication: 25
linked author: Lange, Christoph
linked information resource: Genome-wide association scan of quantitative traits for attention deficit hyperactivity disorder identifies novel associations and confirms candidate gene associations.

Authorship 355957
type: Authorship
author rank in publication: 1
linked author: Lange, Christoph
linked information resource: PBAT: tools for family-based association studies.

Authorship 419303
type: Authorship
author rank in publication: 4
linked author: Lange, Christoph
linked information resource: ADAM33 polymorphisms and phenotype associations in childhood asthma.

Authorship 486166
type: Authorship
author rank in publication: 11
linked author: Lange, Christoph
linked information resource: Association between copy number variants in 16p11.2 and major depressive disorder in a German case-control sample.

Authorship 500293
type: Authorship
author rank in publication: 3
linked author: Lange, Christoph
linked information resource: Overview of the pharmacogenetics of asthma treatment.

Authorship 547652
type: Authorship
author rank in publication: 24
linked author: Lange, Christoph
linked information resource: Genome-wide association scan of attention deficit hyperactivity disorder.

Authorship 52406
type: Authorship
author rank in publication: 6
linked author: Lange, Christoph
linked information resource: On the analysis of sequence data: testing for disease susceptibility loci using patterns of linkage disequilibrium.

Biomedical Informatics
type: Department
type: Organization

Authorship 809271
type: Authorship
author rank in publication: 19
linked author: Lange, Christoph
linked information resource: Investigation of the role of TCF4 rare sequence variants in schizophrenia.

Authorship 808238
type: Authorship
author rank in publication: 6
linked author: Lange, Christoph
linked information resource: Using Network Methodology to Infer Population Substructure.

Investigation of the role of TCF4 rare sequence variants in schizophrenia.
PubMed Identifier: 26010163
author list: Basmanav FB, Forstner AJ, Fier H, Herms S, Meier S, Degenhardt F, Hoffmann P, Barth S, Fricker N, Strohmaier J, Witt SH, Ludwig M, Schmael C, Moebus S, Maier W, Mössner R, Rujescu D, Rietschel M, Lange C, Nöthen MM, Cichon S
published in: American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics
information resource reference: Investigation of the role of TCF4 rare sequence variants in schizophrenia. Am J Med Genet B Neuropsychiatr Genet. 2015 Jul; 168B(5):354-62.
journal title abbreviation: Am J Med Genet B Neuropsychiatr Genet
publication date: 2015-05-22T00:00:00
year: 2015
type: Academic Article
type: Article
type: Document
type: Information Resource

Using Network Methodology to Infer Population Substructure.
PubMed Identifier: 26098940
author list: Prokopenko D, Hecker J, Silverman E, Nöthen MM, Schmid M, Lange C, Loehlein Fier H
published in: PloS one
information resource reference: Using Network Methodology to Infer Population Substructure. PLoS One. 2015; 10(6):e0130708.
journal title abbreviation: PLoS One
publication date: 2015-06-22T00:00:00
year: 2015
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 355088
type: Authorship
author rank in publication: 3
linked author: Lange, Christoph
linked information resource: https://connects.catalyst.harvard.edu/Profiles/profile/1041185

Authorship 813942
type: Authorship
author rank in publication: 3
linked author: Lange, Christoph
linked information resource: Integrating Multiple Correlated Phenotypes for Genetic Association Analysis by Maximizing Heritability.

Integrating Multiple Correlated Phenotypes for Genetic Association Analysis by Maximizing Heritability.
PubMed Identifier: 26111731
author list: Zhou JJ, Cho MH, Lange C, Lutz S, Silverman EK, Laird NM
published in: Human heredity
information resource reference: Integrating Multiple Correlated Phenotypes for Genetic Association Analysis by Maximizing Heritability. Hum Hered. 2015; 79(2):93-104.
journal title abbreviation: Hum Hered
publication date: 2015-06-20T00:00:00
year: 2015
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 819085
type: Authorship
author rank in publication: 9
linked author: Lange, Christoph
linked information resource: Bifunctional T-cell-derived cytokines for the diagnosis of tuberculosis and treatment monitoring.

Authorship 821346
type: Authorship
author rank in publication: 3
linked author: Lange, Christoph
linked information resource: Availability, price and affordability of anti-tuberculosis drugs in Europe: a TBNET survey.

Availability, price and affordability of anti-tuberculosis drugs in Europe: a TBNET survey.
PubMed Identifier: 25395035
author list: Günther G, Gomez GB, Lange C, Rupert S, van Leth F
published in: The European respiratory journal
information resource reference: Availability, price and affordability of anti-tuberculosis drugs in Europe: a TBNET survey. Eur Respir J. 2015 Apr; 45(4):1081-8.
journal title abbreviation: Eur Respir J
publication date: 2014-11-13T00:00:00
year: 2014
type: Academic Article
type: Article
type: Document
type: Information Resource

Bifunctional T-cell-derived cytokines for the diagnosis of tuberculosis and treatment monitoring.
PubMed Identifier: 25171202
author list: Essone PN, Kalsdorf B, Chegou NN, Loxton AG, Kriel M, Preyer R, Ernst M, Walzl G, Lange C
published in: Respiration; international review of thoracic diseases
information resource reference: Bifunctional T-cell-derived cytokines for the diagnosis of tuberculosis and treatment monitoring. Respiration. 2014; 88(3):251-61.
journal title abbreviation: Respiration
publication date: 2014-08-22T00:00:00
year: 2014
type: Academic Article
type: Article
type: Document
type: Information Resource

Adjusting heterogeneous ascertainment bias for genetic association analysis with extended families.
PubMed Identifier: 26286599
author list: Park S, Lee S, Lee Y, Herold C, Hooli B, Mullin K, Park T, Park C, Bertram L, Lange C, Tanzi R, Won S
published in: BMC medical genetics
information resource reference: Adjusting heterogeneous ascertainment bias for genetic association analysis with extended families. BMC Med Genet. 2015 Aug 19; 16:62.
journal title abbreviation: BMC Med Genet
publication date: 2015-08-19T00:00:00
year: 2015
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 447979
type: Authorship
author rank in publication: 4
linked author: Lange, Christoph
linked information resource: Increased expression of beta-defensin 1 (DEFB1) in chronic obstructive pulmonary disease.

Authorship 825603
type: Authorship
author rank in publication: 10
linked author: Lange, Christoph
linked information resource: Adjusting heterogeneous ascertainment bias for genetic association analysis with extended families.

Authorship 523637
type: Authorship
author rank in publication: 5
linked author: Lange, Christoph
linked information resource: Integration of genomic and genetic approaches implicates IREB2 as a COPD susceptibility gene.

Authorship 70790
type: Authorship
author rank in publication: 8
linked author: Lange, Christoph
linked information resource: Genome-wide association analysis of body mass in chronic obstructive pulmonary disease.

Authorship 390241
type: Authorship
author rank in publication: 3
linked author: Lange, Christoph
linked information resource: TOLL-like receptor 10 genetic variation is associated with asthma in two independent samples.

Authorship 431094
type: Authorship
author rank in publication: 5
linked author: Lange, Christoph
linked information resource: Genome-wide association studies of family data in pharmacogenetics: a case study.

Authorship 525646
type: Authorship
author rank in publication: 15
linked author: Lange, Christoph
linked information resource: Genomic screening and replication using the same data set in family-based association testing.

Authorship 850380
type: Authorship
author rank in publication: 22
linked author: Lange, Christoph
linked information resource: A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.

A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.
PubMed Identifier: 26634245
author list: Lutz SM, Cho MH, Young K, Hersh CP, Castaldi PJ, McDonald ML, Regan E, Mattheisen M, DeMeo DL, Parker M, Foreman M, Make BJ, Jensen RL, Casaburi R, Lomas DA, Bhatt SP, Bakke P, Gulsvik A, Crapo JD, Beaty TH, Laird NM, Lange C, Hokanson JE, Silverman EK
published in: BMC genetics
information resource reference: A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry. BMC Genet. 2015 Dec 03; 16:138.
journal title abbreviation: BMC Genet
publication date: 2015-12-03T00:00:00
year: 2015
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 856485
type: Authorship
author rank in publication: 3
linked author: Lange, Christoph
linked information resource: On the Recombination Rate Estimation in the Presence of Population Substructure.

On the Recombination Rate Estimation in the Presence of Population Substructure.
PubMed Identifier: 26716445
author list: Hecker J, Prokopenko D, Lange C, Fier HL
published in: PloS one
information resource reference: On the Recombination Rate Estimation in the Presence of Population Substructure. PLoS One. 2015; 10(12):e0145152.
journal title abbreviation: PLoS One
publication date: 2015-12-30T00:00:00
year: 2015
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 458901
type: Authorship
author rank in publication: 6
linked author: Lange, Christoph
linked information resource: Most antiviral CD8 T cells during chronic viral infection do not express high levels of perforin and are not directly cytotoxic.

Authorship 494185
type: Authorship
author rank in publication: 7
linked author: Lange, Christoph
linked information resource: Family-based association test for time-to-onset data with time-dependent differences between the hazard functions.

Authorship 512553
type: Authorship
author rank in publication: 9
linked author: Lange, Christoph
linked information resource: On the follow-up of genome-wide association studies: an overall test for the most promising SNPs.

Authorship 857874
type: Authorship
author rank in publication: 1
linked author: Lange, Christoph
linked information resource: Viral Load and Risk of Tuberculosis in HIV Infection.

Viral Load and Risk of Tuberculosis in HIV Infection.
PubMed Identifier: 26761521
author list: Lange C, van Leth F, Sester M
published in: Journal of acquired immune deficiency syndromes (1999)
information resource reference: Viral Load and Risk of Tuberculosis in HIV Infection. J Acquir Immune Defic Syndr. 2016 Feb 01; 71(2):e51-3.
journal title abbreviation: J Acquir Immune Defic Syndr
publication date: 2016-02-01T00:00:00
year: 2016
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 57922
type: Authorship
author rank in publication: 27
linked author: Lange, Christoph
linked information resource: Association between schizophrenia and common variation in neurocan (NCAN), a genetic risk factor for bipolar disorder.

Authorship 866598
type: Authorship
author rank in publication: 33
linked author: Lange, Christoph
linked information resource: Risk Assessment of Tuberculosis in Contacts by IFN-? Release Assays. A Tuberculosis Network European Trials Group Study.

Authorship 865538
type: Authorship
author rank in publication: 29
linked author: Lange, Christoph
linked information resource: Risk assessment of tuberculosis in immunocompromised patients. A TBNET study.

Authorship 870827
type: Authorship
author rank in publication: 4
linked author: Lange, Christoph
linked information resource: Development of a one-step probe based molecular assay for rapid immunodiagnosis of infection with M. tuberculosis using dried blood spots.

Risk Assessment of Tuberculosis in Contacts by IFN-? Release Assays. A Tuberculosis Network European Trials Group Study.
PubMed Identifier: 25763458
author list: Zellweger JP, Sotgiu G, Block M, Dore S, Altet N, Blunschi R, Bogyi M, Bothamley G, Bothe C, Codecasa L, Costa P, Dominguez J, Duarte R, Fløe A, Fresard I, García-García JM, Goletti D, Halm P, Hellwig D, Henninger E, Heykes-Uden H, Horn L, Kruczak K, Latorre I, Pache G, Rath H, Ringshausen FC, Ruiz AS, Solovic I, Souza-Galvão ML, Widmer U, Witte P, Lange C
published in: American journal of respiratory and critical care medicine
information resource reference: Risk Assessment of Tuberculosis in Contacts by IFN-? Release Assays. A Tuberculosis Network European Trials Group Study. Am J Respir Crit Care Med. 2015 May 15; 191(10):1176-84.
journal title abbreviation: Am J Respir Crit Care Med
publication date: 2015-05-15T00:00:00
year: 2015
type: Academic Article
type: Article
type: Document
type: Information Resource

Development of a one-step probe based molecular assay for rapid immunodiagnosis of infection with M. tuberculosis using dried blood spots.
PubMed Identifier: 25184553
author list: Blauenfeldt T, Heyckendorf J, Graff Jensen S, Lange C, Drabe C, Hermansen TS, de Thurah L, Lillebaek T, Eugen-Olsen J, Seersholm N, Hoff S, Bonde J, Ruhwald M
published in: PloS one
information resource reference: Development of a one-step probe based molecular assay for rapid immunodiagnosis of infection with M. tuberculosis using dried blood spots. PLoS One. 2014; 9(9):e105628.
journal title abbreviation: PLoS One
publication date: 2014-09-03T00:00:00
year: 2014
type: Academic Article
type: Article
type: Document
type: Information Resource

Risk assessment of tuberculosis in immunocompromised patients. A TBNET study.
PubMed Identifier: 25303140
author list: Sester M, van Leth F, Bruchfeld J, Bumbacea D, Cirillo DM, Dilektasli AG, Domínguez J, Duarte R, Ernst M, Eyuboglu FO, Gerogianni I, Girardi E, Goletti D, Janssens JP, Julander I, Lange B, Latorre I, Losi M, Markova R, Matteelli A, Milburn H, Ravn P, Scholman T, Soccal PM, Straub M, Wagner D, Wolf T, Yalcin A, Lange C
published in: American journal of respiratory and critical care medicine
information resource reference: Risk assessment of tuberculosis in immunocompromised patients. A TBNET study. Am J Respir Crit Care Med. 2014 Nov 15; 190(10):1168-76.
journal title abbreviation: Am J Respir Crit Care Med
publication date: 2014-11-15T00:00:00
year: 2014
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 341874
type: Authorship
author rank in publication: 12
linked author: Lange, Christoph
linked information resource: Asthma-susceptibility variants identified using probands in case-control and family-based analyses.

Authorship 880818
type: Authorship
author rank in publication: 7
linked author: Lange, Christoph
linked information resource: Utilizing the Jaccard index to reveal population stratification in sequencing data: a simulation study and an application to the 1000 Genomes Project.

Utilizing the Jaccard index to reveal population stratification in sequencing data: a simulation study and an application to the 1000 Genomes Project.
PubMed Identifier: 26722118
author list: Prokopenko D, Hecker J, Silverman EK, Pagano M, Nöthen MM, Dina C, Lange C, Fier HL
published in: Bioinformatics (Oxford, England)
information resource reference: Utilizing the Jaccard index to reveal population stratification in sequencing data: a simulation study and an application to the 1000 Genomes Project. Bioinformatics. 2016 05 01; 32(9):1366-72.
journal title abbreviation: Bioinformatics
publication date: 2015-12-31T00:00:00
year: 2015
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 883439
type: Authorship
author rank in publication: 8
linked author: Lange, Christoph
linked information resource: Programmatic Management of Drug-Resistant Tuberculosis: An Updated Research Agenda.

Programmatic Management of Drug-Resistant Tuberculosis: An Updated Research Agenda.
PubMed Identifier: 27223622
author list: Mitnick CD, Rodriguez CA, Hatton ML, Brigden G, Cobelens F, Grobusch MP, Horsburgh R, Lange C, Lienhardt C, Oren E, Podewils LJ, Seaworth B, van den Hof S, Daley CL, Gebhard AC, Wares F
published in: PloS one
information resource reference: Programmatic Management of Drug-Resistant Tuberculosis: An Updated Research Agenda. PLoS One. 2016; 11(5):e0155968.
journal title abbreviation: PLoS One
publication date: 2016-05-25T00:00:00
year: 2016
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 887660
type: Authorship
author rank in publication: 2
linked author: Lange, Christoph
linked information resource: Exome Sequencing Analysis in Severe, Early-Onset Chronic Obstructive Pulmonary Disease.

Exome Sequencing Analysis in Severe, Early-Onset Chronic Obstructive Pulmonary Disease.
PubMed Identifier: 26736064
author list: Qiao D, Lange C, Beaty TH, Crapo JD, Barnes KC, Bamshad M, Hersh CP, Morrow J, Pinto-Plata VM, Marchetti N, Bueno R, Celli BR, Criner GJ, Silverman EK, Cho MH
published in: American journal of respiratory and critical care medicine
information resource reference: Exome Sequencing Analysis in Severe, Early-Onset Chronic Obstructive Pulmonary Disease. Am J Respir Crit Care Med. 2016 06 15; 193(12):1353-63.
journal title abbreviation: Am J Respir Crit Care Med
publication date: 2016-06-15T00:00:00
year: 2016
type: Academic Article
type: Article
type: Document
type: Information Resource

Lutz, Sharon
eCommons Login: SML20
first name: Sharon
last name: Lutz
full name: Sharon Marie Lutz, Ph.D.
has faculty rank: Associate Professor
Person ID: 88131
person in primary position: Associate Professor of Population Medicine
type: Agent
type: Person
preferred title: Associate Professor of Population Medicine

Assistant Professor
sort order: 2
type: Faculty Rank

Associate Professor
sort order: 1
type: Faculty Rank

Full Professor
sort order: 0
type: Faculty Rank

Lecturer
sort order: 3
type: Faculty Rank

Authorship 895817
type: Authorship
author rank in publication: 9
linked author: Lange, Christoph
linked information resource: Lipoarabinomannan-Responsive Polycytotoxic T Cells Are Associated with Protection in Human Tuberculosis.

Lipoarabinomannan-Responsive Polycytotoxic T Cells Are Associated with Protection in Human Tuberculosis.
PubMed Identifier: 26882070
author list: Busch M, Herzmann C, Kallert S, Zimmermann A, Höfer C, Mayer D, Zenk SF, Muche R, Lange C, Bloom BR, Modlin RL, Stenger S
published in: American journal of respiratory and critical care medicine
information resource reference: Lipoarabinomannan-Responsive Polycytotoxic T Cells Are Associated with Protection in Human Tuberculosis. Am J Respir Crit Care Med. 2016 08 01; 194(3):345-55.
journal title abbreviation: Am J Respir Crit Care Med
publication date: 2016-08-01T00:00:00
year: 2016
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 505572
type: Authorship
author rank in publication: 3
linked author: Lange, Christoph
linked information resource: CD8 T cells specific for human immunodeficiency virus, Epstein-Barr virus, and cytomegalovirus lack molecules for homing to lymphoid sites of infection.

Authorship 896945
type: Authorship
author rank in publication: 2
linked author: Lange, Christoph
linked information resource: High Rates of Treatment Success in Pulmonary Multidrug-Resistant Tuberculosis by Individually Tailored Treatment Regimens.

High Rates of Treatment Success in Pulmonary Multidrug-Resistant Tuberculosis by Individually Tailored Treatment Regimens.
PubMed Identifier: 27163360
author list: Olaru ID, Lange C, Indra A, Meidlinger L, Huhulescu S, Rumetshofer R
published in: Annals of the American Thoracic Society
information resource reference: High Rates of Treatment Success in Pulmonary Multidrug-Resistant Tuberculosis by Individually Tailored Treatment Regimens. Ann Am Thorac Soc. 2016 08; 13(8):1271-8.
journal title abbreviation: Ann Am Thorac Soc
publication date: 2016-08-01T00:00:00
year: 2016
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 521308
type: Authorship
author rank in publication: 2
linked author: Lange, Christoph
linked information resource: Genome-wide association analysis reveals putative Alzheimer's disease susceptibility loci in addition to APOE.

Common Genetic Determinants of Asthma and COPD-PROGRAM PROJECT
end date: 2014-01-31
principal investigator name: WEISS, SCOTT T
start date: 2007-03-23
type: Grant
sponsor award id: P01HL083069

Systems Biology of Airway Disease
end date: 2021-07-31
principal investigator name: WEISS, SCOTT T
start date: 2016-09-01
type: Grant
sponsor award id: P01HL132825

Novel Statistical Approaches to Mental Health Phenotype Analysis in GWA Studies
end date: 2016-03-31
principal investigator name: LANGE, CHRISTOPH
start date: 2007-12-01
type: Grant
sponsor award id: R01MH081862

A New Approach to Mental Health Phenotypes in Family Genomewide Association
end date: 2014-11-30
principal investigator name: LANGE, CHRISTOPH
start date: 2009-12-01
type: Grant
sponsor award id: R01MH087590

Principal Investigator
type: Researcher Role
researcher role of: Lange, Christoph
contributes to: Novel Statistical Approaches to Mental Health Phenotype Analysis in GWA Studies

Co-Principal Investigator
type: Researcher Role
researcher role of: Lange, Christoph
contributes to: Systems Biology of Airway Disease

Principal Investigator
type: Researcher Role
researcher role of: Lange, Christoph
contributes to: A New Approach to Mental Health Phenotypes in Family Genomewide Association

Co-Principal Investigator
type: Researcher Role
researcher role of: Lange, Christoph
contributes to: Common Genetic Determinants of Asthma and COPD-PROGRAM PROJECT

665 Huntington Ave
type: Address
address line 1: Harvard School of Public Hlth
address line 2: Dept of Biostatistics
address line 3: 665 Huntington Ave
city: Boston
postal code: 02115
state or province: MA

Preparing Association Analysis Software Tools for Next Generation Sequencing Data
end date: 2020-06-30
principal investigator name: LANGE, CHRISTOPH
start date: 2016-09-27
type: Grant
sponsor award id: R01HG008976

Principal Investigator
type: Researcher Role
researcher role of: Lange, Christoph
contributes to: Preparing Association Analysis Software Tools for Next Generation Sequencing Data

Authorship 925992
type: Authorship
author rank in publication: 5
linked author: Lange, Christoph
linked information resource: Maximizing the Power of Genome-Wide Association Studies: A Novel Class of Powerful Family-Based Association Tests.

Maximizing the Power of Genome-Wide Association Studies: A Novel Class of Powerful Family-Based Association Tests.
PubMed Identifier: 22582089
author list: Won S, Bertram L, Becker D, Tanzi RE, Lange C
published in: Statistics in biosciences
information resource reference: Maximizing the Power of Genome-Wide Association Studies: A Novel Class of Powerful Family-Based Association Tests. Stat Biosci. 2009 Nov; 1(2):125-143.
journal title abbreviation: Stat Biosci
publication date: 2009-11-01T00:00:00
year: 2009
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 486156
type: Authorship
author rank in publication: 6
linked author: Lange, Christoph
linked information resource: Family-based association analysis of beta2-adrenergic receptor polymorphisms in the childhood asthma management program.

Authorship 283024
type: Authorship
author rank in publication: 5
linked author: Lange, Christoph
linked information resource: On dichotomizing phenotypes in family-based association tests: quantitative phenotypes are not always the optimal choice.

Authorship 449820
type: Authorship
author rank in publication: 5
linked author: Lange, Christoph
linked information resource: On the frequency of copy number variants.

Authorship 947876
type: Authorship
author rank in publication: 14
linked author: Lange, Christoph
linked information resource: Body mass index change in gastrointestinal cancer and chronic obstructive pulmonary disease is associated with Dedicator of Cytokinesis 1.

Body mass index change in gastrointestinal cancer and chronic obstructive pulmonary disease is associated with Dedicator of Cytokinesis 1.
PubMed Identifier: 28044437
author list: McDonald MN, Won S, Mattheisen M, Castaldi PJ, Cho MH, Rutten E, Hardin M, Yip WK, Rennard SI, Lomas DA, Wouters EFM, Agusti A, Casaburi R, Lange CP, O'Connor G, Hersh CP, Silverman EK
published in: Journal of cachexia, sarcopenia and muscle
information resource reference: Body mass index change in gastrointestinal cancer and chronic obstructive pulmonary disease is associated with Dedicator of Cytokinesis 1. J Cachexia Sarcopenia Muscle. 2017 Jun; 8(3):428-436.
journal title abbreviation: J Cachexia Sarcopenia Muscle
publication date: 2017-01-02T00:00:00
year: 2017
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 486324
type: Authorship
author rank in publication: 4
linked author: Lange, Christoph
linked information resource: A new testing strategy to identify rare variants with either risk or protective effect on disease.

Authorship 491265
type: Authorship
author rank in publication: 2
linked author: Lange, Christoph
linked information resource: Estimating the number of unseen variants in the human genome.

Authorship 948569
type: Authorship
author rank in publication: 4
linked author: Lange, Christoph
linked information resource: A general approach to testing for pleiotropy with rare and common variants.

A general approach to testing for pleiotropy with rare and common variants.
PubMed Identifier: 27900789
author list: Lutz SM, Fingerlin TE, Hokanson JE, Lange C
published in: Genetic epidemiology
information resource reference: A general approach to testing for pleiotropy with rare and common variants. Genet Epidemiol. 2017 Feb; 41(2):163-170.
journal title abbreviation: Genet Epidemiol
publication date: 2016-11-30T00:00:00
year: 2016
type: Academic Article
type: Article
type: Document
type: Information Resource

Prokopenko, Dmitry
eCommons Login: DP221
first name: Dmitry
last name: Prokopenko
full name: Dmitry Prokopenko, Ph.D.
has faculty rank: Assistant Professor
Person ID: 155694
person in primary position: Assistant Professor of Neurology
type: Agent
type: Person
preferred title: Assistant Professor of Neurology

Univariate and multivariate family-based association analysis of the IL-13 ARG130GLN polymorphism in the Childhood Asthma Management Program.
PubMed Identifier: 12432502
author list: DeMeo DL, Lange C, Silverman EK, Senter JM, Drazen JM, Barth MJ, Laird N, Weiss ST
published in: Genetic epidemiology
information resource reference: Univariate and multivariate family-based association analysis of the IL-13 ARG130GLN polymorphism in the Childhood Asthma Management Program. Genet Epidemiol. 2002 Nov; 23(4):335-48.
journal title abbreviation: Genet Epidemiol
publication date: 2002-11-01T00:00:00
year: 2002
type: Academic Article
type: Article
type: Document
type: Information Resource

Chromosome 12q harbors multiple genetic loci related to asthma and asthma-related phenotypes.
PubMed Identifier: 12913068
author list: Raby BA, Silverman EK, Lazarus R, Lange C, Kwiatkowski DJ, Weiss ST
published in: Human molecular genetics
information resource reference: Chromosome 12q harbors multiple genetic loci related to asthma and asthma-related phenotypes. Hum Mol Genet. 2003 Aug 15; 12(16):1973-9.
journal title abbreviation: Hum Mol Genet
publication date: 2003-08-15T00:00:00
year: 2003
type: Academic Article
type: Article
type: Document
type: Information Resource

A new powerful non-parametric two-stage approach for testing multiple phenotypes in family-based association studies.
PubMed Identifier: 14614234
author list: Lange C, Lyon H, DeMeo D, Raby B, Silverman EK, Weiss ST
published in: Human heredity
information resource reference: A new powerful non-parametric two-stage approach for testing multiple phenotypes in family-based association studies. Hum Hered. 2003; 56(1-3):10-7.
journal title abbreviation: Hum Hered
publication date: 2003-01-01T00:00:00
year: 2003
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 961459
type: Authorship
author rank in publication: 2
linked author: Lange, Christoph
linked information resource: Gene-based segregation method for identifying rare variants in family-based sequencing studies.

Gene-based segregation method for identifying rare variants in family-based sequencing studies.
PubMed Identifier: 28191685
author list: Qiao D, Lange C, Laird NM, Won S, Hersh CP, Morrow J, Hobbs BD, Lutz SM, Ruczinski I, Beaty TH, Silverman EK, Cho MH
published in: Genetic epidemiology
information resource reference: Gene-based segregation method for identifying rare variants in family-based sequencing studies. Genet Epidemiol. 2017 05; 41(4):309-319.
journal title abbreviation: Genet Epidemiol
publication date: 2017-02-13T00:00:00
year: 2017
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 968532
type: Authorship
author rank in publication: 1
linked author: Lange, Christoph
linked information resource: Clinical Application of Interferon-? Release Assays for the Prevention of Tuberculosis in Countries with Low Incidence.

Clinical Application of Interferon-? Release Assays for the Prevention of Tuberculosis in Countries with Low Incidence.
PubMed Identifier: 28217762
author list: Lange C, Mandalakas AM, Kalsdorf B, Denkinger CM, Sester M
published in: Pathogens & immunity
information resource reference: Clinical Application of Interferon-? Release Assays for the Prevention of Tuberculosis in Countries with Low Incidence. Pathog Immun. 2016; 1(2):308-329.
journal title abbreviation: Pathog Immun
publication date: 2016-01-04T00:00:00
year: 2016
type: Academic Article
type: Article
type: Document
type: Information Resource

New powerful approaches for family-based association tests with longitudinal measurements.
PubMed Identifier: 18798838
author list: Ding X, Lange C, Xu X, Laird N
published in: Annals of human genetics
information resource reference: New powerful approaches for family-based association tests with longitudinal measurements. Ann Hum Genet. 2009 Jan; 73(1):74-83.
journal title abbreviation: Ann Hum Genet
publication date: 2008-09-16T00:00:00
year: 2008
type: Academic Article
type: Article
type: Document
type: Information Resource

Parsing the effects of individual SNPs in candidate genes with family data.
PubMed Identifier: 19996607
author list: Hoffmann TJ, Lange C, Vansteelandt S, Raby BA, DeMeo DL, Silverman EK, Weiss ST, Laird NM
published in: Human heredity
information resource reference: Parsing the effects of individual SNPs in candidate genes with family data. Hum Hered. 2010; 69(2):91-103.
journal title abbreviation: Hum Hered
publication date: 2009-12-04T00:00:00
year: 2009
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 972100
type: Authorship
author rank in publication: 3
linked author: Lange, Christoph
linked information resource: Identification of genetic outliers due to sub-structure and cryptic relationships.

Authorship 973167
type: Authorship
author rank in publication: 8
linked author: Lange, Christoph
linked information resource: On the association analysis of genome-sequencing data: A spatial clustering approach for partitioning the entire genome into nonoverlapping windows.

Identification of genetic outliers due to sub-structure and cryptic relationships.
PubMed Identifier: 28334167
author list: Schlauch D, Fier H, Lange C
published in: Bioinformatics (Oxford, England)
information resource reference: Identification of genetic outliers due to sub-structure and cryptic relationships. Bioinformatics. 2017 Jul 01; 33(13):1972-1979.
journal title abbreviation: Bioinformatics
publication date: 2017-07-01T00:00:00
year: 2017
type: Academic Article
type: Article
type: Document
type: Information Resource

On the association analysis of genome-sequencing data: A spatial clustering approach for partitioning the entire genome into nonoverlapping windows.
PubMed Identifier: 28318110
author list: Loehlein Fier H, Prokopenko D, Hecker J, Cho MH, Silverman EK, Weiss ST, Tanzi RE, Lange C
published in: Genetic epidemiology
information resource reference: On the association analysis of genome-sequencing data: A spatial clustering approach for partitioning the entire genome into nonoverlapping windows. Genet Epidemiol. 2017 05; 41(4):332-340.
journal title abbreviation: Genet Epidemiol
publication date: 2017-03-20T00:00:00
year: 2017
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 974302
type: Authorship
author rank in publication: 5
linked author: Lange, Christoph
linked information resource: Reporting Correct p Values in VEGAS Analyses.

Authorship 974723
type: Authorship
author rank in publication: 27
linked author: Lange, Christoph
linked information resource: The epidemiology, pathogenesis, transmission, diagnosis, and management of multidrug-resistant, extensively drug-resistant, and incurable tuberculosis.

The epidemiology, pathogenesis, transmission, diagnosis, and management of multidrug-resistant, extensively drug-resistant, and incurable tuberculosis.
PubMed Identifier: 28344011
author list: Dheda K, Gumbo T, Maartens G, Dooley KE, McNerney R, Murray M, Furin J, Nardell EA, London L, Lessem E, Theron G, van Helden P, Niemann S, Merker M, Dowdy D, Van Rie A, Siu GK, Pasipanodya JG, Rodrigues C, Clark TG, Sirgel FA, Esmail A, Lin HH, Atre SR, Schaaf HS, Chang KC, Lange C, Nahid P, Udwadia ZF, Horsburgh CR, Churchyard GJ, Menzies D, Hesseling AC, Nuermberger E, McIlleron H, Fennelly KP, Goemaere E, Jaramillo E, Low M, Jara CM, Padayatchi N, Warren RM
published in: The Lancet. Respiratory medicine
information resource reference: The epidemiology, pathogenesis, transmission, diagnosis, and management of multidrug-resistant, extensively drug-resistant, and incurable tuberculosis. Lancet Respir Med. 2017 Mar 15.
journal title abbreviation: Lancet Respir Med
publication date: 2017-03-15T00:00:00
year: 2017
type: Academic Article
type: Article
type: Document
type: Information Resource

Reporting Correct p Values in VEGAS Analyses.
PubMed Identifier: 28345502
author list: Hecker J, Maaser A, Prokopenko D, Fier HL, Lange C
published in: Twin research and human genetics : the official journal of the International Society for Twin Studies
information resource reference: Reporting Correct p Values in VEGAS Analyses. Twin Res Hum Genet. 2017 06; 20(3):257-259.
journal title abbreviation: Twin Res Hum Genet
publication date: 2017-03-27T00:00:00
year: 2017
type: Academic Article
type: Article
type: Document
type: Information Resource

PBAT: tools for family-based association studies.
PubMed Identifier: 14740322
author list: Lange C, DeMeo D, Silverman EK, Weiss ST, Laird NM
published in: American journal of human genetics
information resource reference: PBAT: tools for family-based association studies. Am J Hum Genet. 2004 Feb; 74(2):367-9.
journal title abbreviation: Am J Hum Genet
publication date: 2004-02-01T00:00:00
year: 2004
type: Academic Article
type: Article
type: Document
type: Information Resource

Increased expression of the natural killer cell inhibitory receptor CD85j/ILT2 on antigen-specific effector CD8 T cells and its impact on CD8 T-cell function.
PubMed Identifier: 15270723
author list: Ince MN, Harnisch B, Xu Z, Lee SK, Lange C, Moretta L, Lederman M, Lieberman J
published in: Immunology
information resource reference: Increased expression of the natural killer cell inhibitory receptor CD85j/ILT2 on antigen-specific effector CD8 T cells and its impact on CD8 T-cell function. Immunology. 2004 Aug; 112(4):531-42.
journal title abbreviation: Immunology
publication date: 2004-08-01T00:00:00
year: 2004
type: Academic Article
type: Article
type: Document
type: Information Resource

Single-nucleotide polymorphism rs498055 on chromosome 10q24 is not associated with Alzheimer disease in two independent family samples.
PubMed Identifier: 16773580
author list: Bertram L, Hsiao M, Lange C, Blacker D, Tanzi RE
published in: American journal of human genetics
information resource reference: Single-nucleotide polymorphism rs498055 on chromosome 10q24 is not associated with Alzheimer disease in two independent family samples. Am J Hum Genet. 2006 Jul; 79(1):180-3; author reply 183-4.
journal title abbreviation: Am J Hum Genet
publication date: 2006-07-01T00:00:00
year: 2006
type: Academic Article
type: Article
type: Document
type: Information Resource

Power and design considerations for a general class of family-based association tests: quantitative traits.
PubMed Identifier: 12454799
author list: Lange C, DeMeo DL, Laird NM
published in: American journal of human genetics
information resource reference: Power and design considerations for a general class of family-based association tests: quantitative traits. Am J Hum Genet. 2002 Dec; 71(6):1330-41.
journal title abbreviation: Am J Hum Genet
publication date: 2002-11-21T00:00:00
year: 2002
type: Academic Article
type: Article
type: Document
type: Information Resource

Role of common and rare APP DNA sequence variants in Alzheimer disease.
PubMed Identifier: 22491860
author list: Hooli BV, Mohapatra G, Mattheisen M, Parrado AR, Roehr JT, Shen Y, Gusella JF, Moir R, Saunders AJ, Lange C, Tanzi RE, Bertram L
published in: Neurology
information resource reference: Role of common and rare APP DNA sequence variants in Alzheimer disease. Neurology. 2012 Apr 17; 78(16):1250-7.
journal title abbreviation: Neurology
publication date: 2012-04-04T00:00:00
year: 2012
type: Academic Article
type: Article
type: Document
type: Information Resource

The transforming growth factor-beta1 (TGFB1) gene is associated with chronic obstructive pulmonary disease (COPD).
PubMed Identifier: 15175276
author list: Celedón JC, Lange C, Raby BA, Litonjua AA, Palmer LJ, DeMeo DL, Reilly JJ, Kwiatkowski DJ, Chapman HA, Laird N, Sylvia JS, Hernandez M, Speizer FE, Weiss ST, Silverman EK
published in: Human molecular genetics
information resource reference: The transforming growth factor-beta1 (TGFB1) gene is associated with chronic obstructive pulmonary disease (COPD). Hum Mol Genet. 2004 Aug 01; 13(15):1649-56.
journal title abbreviation: Hum Mol Genet
publication date: 2004-06-02T00:00:00
year: 2004
type: Academic Article
type: Article
type: Document
type: Information Resource

Testing and estimating gene-environment interactions in family-based association studies.
PubMed Identifier: 17970814
author list: Vansteelandt S, Demeo DL, Lasky-Su J, Smoller JW, Murphy AJ, McQueen M, Schneiter K, Celedon JC, Weiss ST, Silverman EK, Lange C
published in: Biometrics
information resource reference: Testing and estimating gene-environment interactions in family-based association studies. Biometrics. 2008 Jun; 64(2):458-67.
journal title abbreviation: Biometrics
publication date: 2007-10-25T00:00:00
year: 2007
type: Academic Article
type: Article
type: Document
type: Information Resource

Using the noninformative families in family-based association tests: a powerful new testing strategy.
PubMed Identifier: 14502464
author list: Lange C, DeMeo D, Silverman EK, Weiss ST, Laird NM
published in: American journal of human genetics
information resource reference: Using the noninformative families in family-based association tests: a powerful new testing strategy. Am J Hum Genet. 2003 Oct; 73(4):801-11.
journal title abbreviation: Am J Hum Genet
publication date: 2003-09-18T00:00:00
year: 2003
type: Academic Article
type: Article
type: Document
type: Information Resource

Genome-wide association scan of attention deficit hyperactivity disorder.
PubMed Identifier: 18980221
author list: Neale BM, Lasky-Su J, Anney R, Franke B, Zhou K, Maller JB, Vasquez AA, Asherson P, Chen W, Banaschewski T, Buitelaar J, Ebstein R, Gill M, Miranda A, Oades RD, Roeyers H, Rothenberger A, Sergeant J, Steinhausen HC, Sonuga-Barke E, Mulas F, Taylor E, Laird N, Lange C, Daly M, Faraone SV
published in: American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics
information resource reference: Genome-wide association scan of attention deficit hyperactivity disorder. Am J Med Genet B Neuropsychiatr Genet. 2008 Dec 05; 147B(8):1337-44.
journal title abbreviation: Am J Med Genet B Neuropsychiatr Genet
publication date: 2008-12-05T00:00:00
year: 2008
type: Academic Article
type: Article
type: Document
type: Information Resource

Overview of the pharmacogenetics of asthma treatment.
PubMed Identifier: 16568148
author list: Weiss ST, Litonjua AA, Lange C, Lazarus R, Liggett SB, Bleecker ER, Tantisira KG
published in: The pharmacogenomics journal
information resource reference: Overview of the pharmacogenetics of asthma treatment. Pharmacogenomics J. 2006 Sep-Oct; 6(5):311-26.
journal title abbreviation: Pharmacogenomics J
publication date: 2006-04-25T00:00:00
year: 2006
type: Academic Article
type: Article
type: Document
type: Information Resource

On a general class of conditional tests for family-based association studies in genetics: the asymptotic distribution, the conditional power, and optimality considerations.
PubMed Identifier: 12214309
author list: Lange C, Laird NM
published in: Genetic epidemiology
information resource reference: On a general class of conditional tests for family-based association studies in genetics: the asymptotic distribution, the conditional power, and optimality considerations. Genet Epidemiol. 2002 Aug; 23(2):165-80.
journal title abbreviation: Genet Epidemiol
publication date: 2002-08-01T00:00:00
year: 2002
type: Academic Article
type: Article
type: Document
type: Information Resource

Paternal history of asthma and airway responsiveness in children with asthma.
PubMed Identifier: 15937295
author list: Raby BA, Van Steen K, Celedón JC, Litonjua AA, Lange C, Weiss ST
published in: American journal of respiratory and critical care medicine
information resource reference: Paternal history of asthma and airway responsiveness in children with asthma. Am J Respir Crit Care Med. 2005 Sep 01; 172(5):552-8.
journal title abbreviation: Am J Respir Crit Care Med
publication date: 2005-06-03T00:00:00
year: 2005
type: Academic Article
type: Article
type: Document
type: Information Resource

Genomic screening and replication using the same data set in family-based association testing.
PubMed Identifier: 15937480
author list: Van Steen K, McQueen MB, Herbert A, Raby B, Lyon H, Demeo DL, Murphy A, Su J, Datta S, Rosenow C, Christman M, Silverman EK, Laird NM, Weiss ST, Lange C
published in: Nature genetics
information resource reference: Genomic screening and replication using the same data set in family-based association testing. Nat Genet. 2005 Jul; 37(7):683-91.
journal title abbreviation: Nat Genet
publication date: 2005-06-05T00:00:00
year: 2005
type: Academic Article
type: Article
type: Document
type: Information Resource

On the analysis of sequence data: testing for disease susceptibility loci using patterns of linkage disequilibrium.
PubMed Identifier: 22125225
author list: Lipman PJ, Yip WK, AlChawa T, Ludwig KU, Mangold E, Lange C
published in: Genetic epidemiology
information resource reference: On the analysis of sequence data: testing for disease susceptibility loci using patterns of linkage disequilibrium. Genet Epidemiol. 2011 Dec; 35(8):880-6.
journal title abbreviation: Genet Epidemiol
publication date: 2011-12-01T00:00:00
year: 2011
type: Academic Article
type: Article
type: Document
type: Information Resource

The SERPINE2 gene is associated with chronic obstructive pulmonary disease.
PubMed Identifier: 16921128
author list: DeMeo D, Mariani T, Lange C, Lake S, Litonjua A, Celedón J, Reilly J, Chapman HA, Sparrow D, Spira A, Beane J, Pinto-Plata V, Speizer FE, Shapiro S, Weiss ST, Silverman EK
published in: Proceedings of the American Thoracic Society
information resource reference: The SERPINE2 gene is associated with chronic obstructive pulmonary disease. Proc Am Thorac Soc. 2006 Aug; 3(6):502.
journal title abbreviation: Proc Am Thorac Soc
publication date: 2006-08-01T00:00:00
year: 2006
type: Academic Article
type: Article
type: Document
type: Information Resource

On dichotomizing phenotypes in family-based association tests: quantitative phenotypes are not always the optimal choice.
PubMed Identifier: 17342772
author list: Fardo D, Celedón JC, Raby BA, Weiss ST, Lange C
published in: Genetic epidemiology
information resource reference: On dichotomizing phenotypes in family-based association tests: quantitative phenotypes are not always the optimal choice. Genet Epidemiol. 2007 Jul; 31(5):376-82.
journal title abbreviation: Genet Epidemiol
publication date: 2007-07-01T00:00:00
year: 2007
type: Academic Article
type: Article
type: Document
type: Information Resource

Accuracy of immunodiagnostic tests for active tuberculosis using single and combined results: a multicenter TBNET-Study.
PubMed Identifier: 18923709
author list: Goletti D, Carrara S, Stefania C, Butera O, Amicosante M, Ernst M, Sauzullo I, Vullo V, Cirillo D, Borroni E, Markova R, Drenska R, Dominguez J, Latorre I, Angeletti C, Navarra A, Petrosillo N, Lauria FN, Ippolito G, Migliori GB, Lange C, Girardi E
published in: PloS one
information resource reference: Accuracy of immunodiagnostic tests for active tuberculosis using single and combined results: a multicenter TBNET-Study. PLoS One. 2008; 3(10):e3417.
journal title abbreviation: PLoS One
publication date: 2008-10-15T00:00:00
year: 2008
type: Academic Article
type: Article
type: Document
type: Information Resource

Gene-environment interaction tests for dichotomous traits in trios and sibships.
PubMed Identifier: 19365860
author list: Hoffmann TJ, Lange C, Vansteelandt S, Laird NM
published in: Genetic epidemiology
information resource reference: Gene-environment interaction tests for dichotomous traits in trios and sibships. Genet Epidemiol. 2009 Dec; 33(8):691-9.
journal title abbreviation: Genet Epidemiol
publication date: 2009-12-01T00:00:00
year: 2009
type: Academic Article
type: Article
type: Document
type: Information Resource

Polymorphisms in toll-like receptor 4 are not associated with asthma or atopy-related phenotypes.
PubMed Identifier: 12406828
author list: Raby BA, Klimecki WT, Laprise C, Renaud Y, Faith J, Lemire M, Greenwood C, Weiland KM, Lange C, Palmer LJ, Lazarus R, Vercelli D, Kwiatkowski DJ, Silverman EK, Martinez FD, Hudson TJ, Weiss ST
published in: American journal of respiratory and critical care medicine
information resource reference: Polymorphisms in toll-like receptor 4 are not associated with asthma or atopy-related phenotypes. Am J Respir Crit Care Med. 2002 Dec 01; 166(11):1449-56.
journal title abbreviation: Am J Respir Crit Care Med
publication date: 2002-09-25T00:00:00
year: 2002
type: Academic Article
type: Article
type: Document
type: Information Resource

Meta-analysis of the INSIG2 association with obesity including 74,345 individuals: does heterogeneity of estimates relate to study design?
PubMed Identifier: 19851442
author list: Heid IM, Huth C, Loos RJ, Kronenberg F, Adamkova V, Anand SS, Ardlie K, Biebermann H, Bjerregaard P, Boeing H, Bouchard C, Ciullo M, Cooper JA, Corella D, Dina C, Engert JC, Fisher E, Francès F, Froguel P, Hebebrand J, Hegele RA, Hinney A, Hoehe MR, Hu FB, Hubacek JA, Humphries SE, Hunt SC, Illig T, Järvelin MR, Kaakinen M, Kollerits B, Krude H, Kumar J, Lange LA, Langer B, Li S, Luchner A, Lyon HN, Meyre D, Mohlke KL, Mooser V, Nebel A, Nguyen TT, Paulweber B, Perusse L, Qi L, Rankinen T, Rosskopf D, Schreiber S, Sengupta S, Sorice R, Suk A, Thorleifsson G, Thorsteinsdottir U, Völzke H, Vimaleswaran KS, Wareham NJ, Waterworth D, Yusuf S, Lindgren C, McCarthy MI, Lange C, Hirschhorn JN, Laird N, Wichmann HE
published in: PLoS genetics
information resource reference: Meta-analysis of the INSIG2 association with obesity including 74,345 individuals: does heterogeneity of estimates relate to study design? PLoS Genet. 2009 Oct; 5(10):e1000694.
journal title abbreviation: PLoS Genet
publication date: 2009-10-23T00:00:00
year: 2009
type: Academic Article
type: Article
type: Document
type: Information Resource

Potential role for IL-2 ELISpot in differentiating recent and remote infection in tuberculosis contact tracing.
PubMed Identifier: 20652022
author list: Krummel B, Strassburg A, Ernst M, Reiling N, Eker B, Rath H, Hoerster R, Wappler W, Glaewe A, Schoellhorn V, Sotgiu G, Lange C
published in: PloS one
information resource reference: Potential role for IL-2 ELISpot in differentiating recent and remote infection in tuberculosis contact tracing. PLoS One. 2010 Jul 20; 5(7):e11670.
journal title abbreviation: PLoS One
publication date: 2010-07-20T00:00:00
year: 2010
type: Academic Article
type: Article
type: Document
type: Information Resource

Extended haplotype in the tumor necrosis factor gene cluster is associated with asthma and asthma-related phenotypes.
PubMed Identifier: 15976383
author list: Randolph AG, Lange C, Silverman EK, Lazarus R, Weiss ST
published in: American journal of respiratory and critical care medicine
information resource reference: Extended haplotype in the tumor necrosis factor gene cluster is associated with asthma and asthma-related phenotypes. Am J Respir Crit Care Med. 2005 Sep 15; 172(6):687-92.
journal title abbreviation: Am J Respir Crit Care Med
publication date: 2005-06-23T00:00:00
year: 2005
type: Academic Article
type: Article
type: Document
type: Information Resource

On the replication of genetic associations: timing can be everything!
PubMed Identifier: 18387595
author list: Lasky-Su J, Lyon HN, Emilsson V, Heid IM, Molony C, Raby BA, Lazarus R, Klanderman B, Soto-Quiros ME, Avila L, Silverman EK, Thorleifsson G, Thorsteinsdottir U, Kronenberg F, Vollmert C, Illig T, Fox CS, Levy D, Laird N, Ding X, McQueen MB, Butler J, Ardlie K, Papoutsakis C, Dedoussis G, O'Donnell CJ, Wichmann HE, Celedón JC, Schadt E, Hirschhorn J, Weiss ST, Stefansson K, Lange C
published in: American journal of human genetics
information resource reference: On the replication of genetic associations: timing can be everything! Am J Hum Genet. 2008 Apr; 82(4):849-58.
journal title abbreviation: Am J Hum Genet
publication date: 2008-04-01T00:00:00
year: 2008
type: Academic Article
type: Article
type: Document
type: Information Resource

Screening and replication using the same data set: testing strategies for family-based studies in which all probands are affected.
PubMed Identifier: 18802462
author list: Murphy A, Weiss ST, Lange C
published in: PLoS genetics
information resource reference: Screening and replication using the same data set: testing strategies for family-based studies in which all probands are affected. PLoS Genet. 2008 Sep 19; 4(9):e1000197.
journal title abbreviation: PLoS Genet
publication date: 2008-09-19T00:00:00
year: 2008
type: Academic Article
type: Article
type: Document
type: Information Resource

Common genetic variation in the GAD1 gene and the entire family of DLX homeobox genes and autism spectrum disorders.
PubMed Identifier: 21302352
author list: Chang SC, Pauls DL, Lange C, Sasanfar R, Santangelo SL
published in: American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics
information resource reference: Common genetic variation in the GAD1 gene and the entire family of DLX homeobox genes and autism spectrum disorders. Am J Med Genet B Neuropsychiatr Genet. 2011 Mar; 156(2):233-9.
journal title abbreviation: Am J Med Genet B Neuropsychiatr Genet
publication date: 2010-12-16T00:00:00
year: 2010
type: Academic Article
type: Article
type: Document
type: Information Resource

Causation and causal inference for genetic effects.
PubMed Identifier: 22864952
author list: Vansteelandt S, Lange C
published in: Human genetics
information resource reference: Causation and causal inference for genetic effects. Hum Genet. 2012 Oct; 131(10):1665-76.
journal title abbreviation: Hum Genet
publication date: 2012-08-03T00:00:00
year: 2012
type: Academic Article
type: Article
type: Document
type: Information Resource

Statistical challenges for genome-wide association studies of suicidality using family data.
PubMed Identifier: 20447807
author list: Lasky-Su J, Lange C
published in: European psychiatry : the journal of the Association of European Psychiatrists
information resource reference: Statistical challenges for genome-wide association studies of suicidality using family data. Eur Psychiatry. 2010 Jun; 25(5):307-9.
journal title abbreviation: Eur Psychiatry
publication date: 2010-05-05T00:00:00
year: 2010
type: Academic Article
type: Article
type: Document
type: Information Resource

Susceptibility to tuberculosis is associated with TLR1 polymorphisms resulting in a lack of TLR1 cell surface expression.
PubMed Identifier: 21642391
author list: Uciechowski P, Imhoff H, Lange C, Meyer CG, Browne EN, Kirsten DK, Schröder AK, Schaaf B, Al-Lahham A, Reinert RR, Reiling N, Haase H, Hatzmann A, Fleischer D, Heussen N, Kleines M, Rink L
published in: Journal of leukocyte biology
information resource reference: Susceptibility to tuberculosis is associated with TLR1 polymorphisms resulting in a lack of TLR1 cell surface expression. J Leukoc Biol. 2011 Aug; 90(2):377-88.
journal title abbreviation: J Leukoc Biol
publication date: 2011-06-03T00:00:00
year: 2011
type: Academic Article
type: Article
type: Document
type: Information Resource

HLA-DQ strikes again: genome-wide association study further confirms HLA-DQ in the diagnosis of asthma among adults.
PubMed Identifier: 23181788
author list: Lasky-Su J, Himes BE, Raby BA, Klanderman BJ, Sylvia JS, Lange C, Melen E, Martinez FD, Israel E, Gauderman J, Gilliland F, Sleiman P, Hakonarson H, Celedón JC, Soto-Quiros M, Avila L, Lima JJ, Irvin CG, Peters SP, Boushey H, Chinchilli VM, Mauger D, Tantisira K, Weiss ST
published in: Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology
information resource reference: HLA-DQ strikes again: genome-wide association study further confirms HLA-DQ in the diagnosis of asthma among adults. Clin Exp Allergy. 2012 Dec; 42(12):1724-33.
journal title abbreviation: Clin Exp Allergy
publication date: 2012-12-01T00:00:00
year: 2012
type: Academic Article
type: Article
type: Document
type: Information Resource

Polymorphisms in IL13, total IgE, eosinophilia, and asthma exacerbations in childhood.
PubMed Identifier: 17561245
author list: Hunninghake GM, Soto-Quirós ME, Avila L, Su J, Murphy A, Demeo DL, Ly NP, Liang C, Sylvia JS, Klanderman BJ, Lange C, Raby BA, Silverman EK, Celedón JC
published in: The Journal of allergy and clinical immunology
information resource reference: Polymorphisms in IL13, total IgE, eosinophilia, and asthma exacerbations in childhood. J Allergy Clin Immunol. 2007 Jul; 120(1):84-90.
journal title abbreviation: J Allergy Clin Immunol
publication date: 2007-06-11T00:00:00
year: 2007
type: Academic Article
type: Article
type: Document
type: Information Resource

Exploring candidate gene associations with neuropsychological performance.
PubMed Identifier: 17579348
author list: McQueen MB, Bertram L, Lange C, Becker KD, Albert MS, Tanzi RE, Blacker D
published in: American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics
information resource reference: Exploring candidate gene associations with neuropsychological performance. Am J Med Genet B Neuropsychiatr Genet. 2007 Dec 05; 144B(8):987-91.
journal title abbreviation: Am J Med Genet B Neuropsychiatr Genet
publication date: 2007-12-05T00:00:00
year: 2007
type: Academic Article
type: Article
type: Document
type: Information Resource

Genomewide weighted hypothesis testing in family-based association studies, with an application to a 100K scan.
PubMed Identifier: 17701906
author list: Ionita-Laza I, McQueen MB, Laird NM, Lange C
published in: American journal of human genetics
information resource reference: Genomewide weighted hypothesis testing in family-based association studies, with an application to a 100K scan. Am J Hum Genet. 2007 Sep; 81(3):607-14.
journal title abbreviation: Am J Hum Genet
publication date: 2007-07-17T00:00:00
year: 2007
type: Academic Article
type: Article
type: Document
type: Information Resource

Recommendations for using standardised phenotypes in genetic association studies.
PubMed Identifier: 19706362
author list: Naylor MG, Weiss ST, Lange C
published in: Human genomics
information resource reference: Recommendations for using standardised phenotypes in genetic association studies. Hum Genomics. 2009 Jul; 3(4):308-19.
journal title abbreviation: Hum Genomics
publication date: 2009-07-01T00:00:00
year: 2009
type: Academic Article
type: Article
type: Document
type: Information Resource

https://connects.catalyst.harvard.edu/Profiles/profile/892063
PubMed Identifier: 20718041
author list: Murphy A, Won S, Rogers A, Chu JH, Raby BA, Lange C
published in: Genetic epidemiology
information resource reference: On the genome-wide analysis of copy number variants in family-based designs: methods for combining family-based and population-based information for testing dichotomous or quantitative traits, or completely ascertained samples. Genet Epidemiol. 2010 Sep; 34(6):582-90.
journal title abbreviation: Genet Epidemiol
publication date: 2010-09-01T00:00:00
year: 2010
type: Academic Article
type: Article
type: Document
type: Information Resource
label: On the genome-wide analysis of copy number variants in family-based designs: methods for combining family-based and population-based information for testing dichotomous or quantitative traits, or completely ascertained samples.

Quantitative trait prediction based on genetic marker-array data, a simulation study.
PubMed Identifier: 21285022
author list: Yip WK, Lange C
published in: Bioinformatics (Oxford, England)
information resource reference: Quantitative trait prediction based on genetic marker-array data, a simulation study. Bioinformatics. 2011 Mar 15; 27(6):745-8.
journal title abbreviation: Bioinformatics
publication date: 2011-01-31T00:00:00
year: 2011
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1015975
type: Authorship
author rank in publication: 3
linked author: Lange, Christoph
linked information resource: PolyGEE: a generalized estimating equation approach to the efficient and robust estimation of polygenic effects in large-scale association studies.

PolyGEE: a generalized estimating equation approach to the efficient and robust estimation of polygenic effects in large-scale association studies.
PubMed Identifier: 28968646
author list: Hecker J, Prokopenko D, Lange C, Fier HL
published in: Biostatistics (Oxford, England)
information resource reference: PolyGEE: a generalized estimating equation approach to the efficient and robust estimation of polygenic effects in large-scale association studies. Biostatistics. 2018 07 01; 19(3):295-306.
journal title abbreviation: Biostatistics
publication date: 2018-07-01T00:00:00
year: 2018
type: Academic Article
type: Article
type: Document
type: Information Resource

Family-based association between Alzheimer's disease and variants in UBQLN1.
PubMed Identifier: 15745979
author list: Bertram L, Hiltunen M, Parkinson M, Ingelsson M, Lange C, Ramasamy K, Mullin K, Menon R, Sampson AJ, Hsiao MY, Elliott KJ, Velicelebi G, Moscarillo T, Hyman BT, Wagner SL, Becker KD, Blacker D, Tanzi RE
published in: The New England journal of medicine
information resource reference: Family-based association between Alzheimer's disease and variants in UBQLN1. N Engl J Med. 2005 Mar 03; 352(9):884-94.
journal title abbreviation: N Engl J Med
publication date: 2005-03-03T00:00:00
year: 2005
type: Academic Article
type: Article
type: Document
type: Information Resource

Proliferation responses to HIVp24 during antiretroviral therapy do not reflect improved immune phenotype or function.
PubMed Identifier: 15090765
author list: Lange CG, Xu Z, Patterson BK, Medvik K, Harnisch B, Asaad R, Valdez H, Lee SJ, Landay A, Lieberman J, Lederman MM
published in: AIDS (London, England)
information resource reference: Proliferation responses to HIVp24 during antiretroviral therapy do not reflect improved immune phenotype or function. AIDS. 2004 Mar 05; 18(4):605-13.
journal title abbreviation: AIDS
publication date: 2004-03-05T00:00:00
year: 2004
type: Academic Article
type: Article
type: Document
type: Information Resource

ADAM33 polymorphisms and phenotype associations in childhood asthma.
PubMed Identifier: 15208587
author list: Raby BA, Silverman EK, Kwiatkowski DJ, Lange C, Lazarus R, Weiss ST
published in: The Journal of allergy and clinical immunology
information resource reference: ADAM33 polymorphisms and phenotype associations in childhood asthma. J Allergy Clin Immunol. 2004 Jun; 113(6):1071-8.
journal title abbreviation: J Allergy Clin Immunol
publication date: 2004-06-01T00:00:00
year: 2004
type: Academic Article
type: Article
type: Document
type: Information Resource

Association of vitamin D receptor gene polymorphisms with childhood and adult asthma.
PubMed Identifier: 15282200
author list: Raby BA, Lazarus R, Silverman EK, Lake S, Lange C, Wjst M, Weiss ST
published in: American journal of respiratory and critical care medicine
information resource reference: Association of vitamin D receptor gene polymorphisms with childhood and adult asthma. Am J Respir Crit Care Med. 2004 Nov 15; 170(10):1057-65.
journal title abbreviation: Am J Respir Crit Care Med
publication date: 2004-07-28T00:00:00
year: 2004
type: Academic Article
type: Article
type: Document
type: Information Resource

Comparison of linkage and association strategies for quantitative traits using the COGA dataset.
PubMed Identifier: 16451712
author list: McQueen MB, Murphy A, Kraft P, Su J, Lazarus R, Laird NM, Lange C, Van Steen K
published in: BMC genetics
information resource reference: Comparison of linkage and association strategies for quantitative traits using the COGA dataset. BMC Genet. 2005 Dec 30; 6 Suppl 1:S96.
journal title abbreviation: BMC Genet
publication date: 2005-12-30T00:00:00
year: 2005
type: Academic Article
type: Article
type: Document
type: Information Resource

A common genetic variant is associated with adult and childhood obesity.
PubMed Identifier: 16614226
author list: Herbert A, Gerry NP, McQueen MB, Heid IM, Pfeufer A, Illig T, Wichmann HE, Meitinger T, Hunter D, Hu FB, Colditz G, Hinney A, Hebebrand J, Koberwitz K, Zhu X, Cooper R, Ardlie K, Lyon H, Hirschhorn JN, Laird NM, Lenburg ME, Lange C, Christman MF
published in: Science (New York, N.Y.)
information resource reference: A common genetic variant is associated with adult and childhood obesity. Science. 2006 Apr 14; 312(5771):279-83.
journal title abbreviation: Science
publication date: 2006-04-14T00:00:00
year: 2006
type: Academic Article
type: Article
type: Document
type: Information Resource

The association of a SNP upstream of INSIG2 with body mass index is reproduced in several but not all cohorts.
PubMed Identifier: 17465681
author list: Lyon HN, Emilsson V, Hinney A, Heid IM, Lasky-Su J, Zhu X, Thorleifsson G, Gunnarsdottir S, Walters GB, Thorsteinsdottir U, Kong A, Gulcher J, Nguyen TT, Scherag A, Pfeufer A, Meitinger T, Brönner G, Rief W, Soto-Quiros ME, Avila L, Klanderman B, Raby BA, Silverman EK, Weiss ST, Laird N, Ding X, Groop L, Tuomi T, Isomaa B, Bengtsson K, Butler JL, Cooper RS, Fox CS, O'Donnell CJ, Vollmert C, Celedón JC, Wichmann HE, Hebebrand J, Stefansson K, Lange C, Hirschhorn JN
published in: PLoS genetics
information resource reference: The association of a SNP upstream of INSIG2 with body mass index is reproduced in several but not all cohorts. PLoS Genet. 2007 Apr 27; 3(4):e61.
journal title abbreviation: PLoS Genet
publication date: 2007-03-07T00:00:00
year: 2007
type: Academic Article
type: Article
type: Document
type: Information Resource

Power calculations for a general class of family-based association tests: dichotomous traits.
PubMed Identifier: 12181775
author list: Lange C, Laird NM
published in: American journal of human genetics
information resource reference: Power calculations for a general class of family-based association tests: dichotomous traits. Am J Hum Genet. 2002 Sep; 71(3):575-84.
journal title abbreviation: Am J Hum Genet
publication date: 2002-08-12T00:00:00
year: 2002
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1028002
type: Authorship
author rank in publication: 7
linked author: Lange, Christoph
linked information resource: Family-based tests for associating haplotypes with general phenotype data: Improving the FBAT-haplotype algorithm.

Family-based tests for associating haplotypes with general phenotype data: Improving the FBAT-haplotype algorithm.
PubMed Identifier: 29159827
author list: Hecker J, Xu X, Townes FW, Loehlein Fier H, Corcoran C, Laird N, Lange C
published in: Genetic epidemiology
information resource reference: Family-based tests for associating haplotypes with general phenotype data: Improving the FBAT-haplotype algorithm. Genet Epidemiol. 2018 02; 42(1):123-126.
journal title abbreviation: Genet Epidemiol
publication date: 2017-11-21T00:00:00
year: 2017
type: Academic Article
type: Article
type: Document
type: Information Resource

Using canonical correlation analysis to discover genetic regulatory variants.
PubMed Identifier: 20485529
author list: Naylor MG, Lin X, Weiss ST, Raby BA, Lange C
published in: PloS one
information resource reference: Using canonical correlation analysis to discover genetic regulatory variants. PLoS One. 2010 May 13; 5(5):e10395.
journal title abbreviation: PLoS One
publication date: 2010-05-13T00:00:00
year: 2010
type: Academic Article
type: Article
type: Document
type: Information Resource

Inferring genetic causal effects on survival data with associated endo-phenotypes.
PubMed Identifier: 21254219
author list: Lipman PJ, Liu KY, Muehlschlegel JD, Body S, Lange C
published in: Genetic epidemiology
information resource reference: Inferring genetic causal effects on survival data with associated endo-phenotypes. Genet Epidemiol. 2011 Feb; 35(2):119-24.
journal title abbreviation: Genet Epidemiol
publication date: 2010-12-31T00:00:00
year: 2010
type: Academic Article
type: Article
type: Document
type: Information Resource

A new testing strategy to identify rare variants with either risk or protective effect on disease.
PubMed Identifier: 21304886
author list: Ionita-Laza I, Buxbaum JD, Laird NM, Lange C
published in: PLoS genetics
information resource reference: A new testing strategy to identify rare variants with either risk or protective effect on disease. PLoS Genet. 2011 Feb 03; 7(2):e1001289.
journal title abbreviation: PLoS Genet
publication date: 2011-02-03T00:00:00
year: 2011
type: Academic Article
type: Article
type: Document
type: Information Resource

PBAT: a comprehensive software package for genome-wide association analysis of complex family-based studies.
PubMed Identifier: 15814068
author list: Van Steen K, Lange C
published in: Human genomics
information resource reference: PBAT: a comprehensive software package for genome-wide association analysis of complex family-based studies. Hum Genomics. 2005 Mar; 2(1):67-9.
journal title abbreviation: Hum Genomics
publication date: 2005-03-01T00:00:00
year: 2005
type: Academic Article
type: Article
type: Document
type: Information Resource

Combined analysis from eleven linkage studies of bipolar disorder provides strong evidence of susceptibility loci on chromosomes 6q and 8q.
PubMed Identifier: 16175504
author list: McQueen MB, Devlin B, Faraone SV, Nimgaonkar VL, Sklar P, Smoller JW, Abou Jamra R, Albus M, Bacanu SA, Baron M, Barrett TB, Berrettini W, Blacker D, Byerley W, Cichon S, Coryell W, Craddock N, Daly MJ, Depaulo JR, Edenberg HJ, Foroud T, Gill M, Gilliam TC, Hamshere M, Jones I, Jones L, Juo SH, Kelsoe JR, Lambert D, Lange C, Lerer B, Liu J, Maier W, Mackinnon JD, McInnis MG, McMahon FJ, Murphy DL, Nothen MM, Nurnberger JI, Pato CN, Pato MT, Potash JB, Propping P, Pulver AE, Rice JP, Rietschel M, Scheftner W, Schumacher J, Segurado R, Van Steen K, Xie W, Zandi PP, Laird NM
published in: American journal of human genetics
information resource reference: Combined analysis from eleven linkage studies of bipolar disorder provides strong evidence of susceptibility loci on chromosomes 6q and 8q. Am J Hum Genet. 2005 Oct; 77(4):582-95.
journal title abbreviation: Am J Hum Genet
publication date: 2005-08-15T00:00:00
year: 2005
type: Academic Article
type: Article
type: Document
type: Information Resource

The SERPINE2 gene is associated with chronic obstructive pulmonary disease.
PubMed Identifier: 16358219
author list: Demeo DL, Mariani TJ, Lange C, Srisuma S, Litonjua AA, Celedon JC, Lake SL, Reilly JJ, Chapman HA, Mecham BH, Haley KJ, Sylvia JS, Sparrow D, Spira AE, Beane J, Pinto-Plata V, Speizer FE, Shapiro SD, Weiss ST, Silverman EK
published in: American journal of human genetics
information resource reference: The SERPINE2 gene is associated with chronic obstructive pulmonary disease. Am J Hum Genet. 2006 Feb; 78(2):253-64.
journal title abbreviation: Am J Hum Genet
publication date: 2005-12-15T00:00:00
year: 2005
type: Academic Article
type: Article
type: Document
type: Information Resource

FBAT-SNP-PC: an approach for multiple markers and single trait in family-based association tests.
PubMed Identifier: 18382091
author list: Rakovski CS, Weiss ST, Laird NM, Lange C
published in: Human heredity
information resource reference: FBAT-SNP-PC: an approach for multiple markers and single trait in family-based association tests. Hum Hered. 2008; 66(2):122-6.
journal title abbreviation: Hum Hered
publication date: 2008-03-31T00:00:00
year: 2008
type: Academic Article
type: Article
type: Document
type: Information Resource

Natriuretic peptide system gene variants are associated with ventricular dysfunction after coronary artery bypass grafting.
PubMed Identifier: 19326473
author list: Fox AA, Collard CD, Shernan SK, Seidman CE, Seidman JG, Liu KY, Muehlschlegel JD, Perry TE, Aranki SF, Lange C, Herman DS, Meitinger T, Lichtner P, Body SC
published in: Anesthesiology
information resource reference: Natriuretic peptide system gene variants are associated with ventricular dysfunction after coronary artery bypass grafting. Anesthesiology. 2009 Apr; 110(4):738-47.
journal title abbreviation: Anesthesiology
publication date: 2009-04-01T00:00:00
year: 2009
type: Academic Article
type: Article
type: Document
type: Information Resource

Stronger evidence for replication of NPPA using genome-wide genotyping data.
PubMed Identifier: 20026756
author list: Rogers AJ, Raby BA, Lima J, Lasky-Su JA, Murphy A, Lazarus R, Klanderman B, Sylvia JS, Ziniti JP, Lange C, Celedón JC, Silverman EK, Weiss ST
published in: American journal of respiratory and critical care medicine
information resource reference: Stronger evidence for replication of NPPA using genome-wide genotyping data. Am J Respir Crit Care Med. 2010 Jan 01; 181(1):96.
journal title abbreviation: Am J Respir Crit Care Med
publication date: 2010-01-01T00:00:00
year: 2010
type: Academic Article
type: Article
type: Document
type: Information Resource

A doubly robust test for gene-environment interaction in family-based studies of affected offspring.
PubMed Identifier: 20154305
author list: Moerkerke B, Vansteelandt S, Lange C
published in: Biostatistics (Oxford, England)
information resource reference: A doubly robust test for gene-environment interaction in family-based studies of affected offspring. Biostatistics. 2010 Apr; 11(2):213-25.
journal title abbreviation: Biostatistics
publication date: 2010-02-12T00:00:00
year: 2010
type: Academic Article
type: Article
type: Document
type: Information Resource

CGene: an R package for implementation of causal genetic analyses.
PubMed Identifier: 21731061
author list: Lipman PJ, Lange C
published in: European journal of human genetics : EJHG
information resource reference: CGene: an R package for implementation of causal genetic analyses. Eur J Hum Genet. 2011 Dec; 19(12):1292-4.
journal title abbreviation: Eur J Hum Genet
publication date: 2011-07-06T00:00:00
year: 2011
type: Academic Article
type: Article
type: Document
type: Information Resource

Mapping of numerous disease-associated expression polymorphisms in primary peripheral blood CD4+ lymphocytes.
PubMed Identifier: 20833654
author list: Murphy A, Chu JH, Xu M, Carey VJ, Lazarus R, Liu A, Szefler SJ, Strunk R, Demuth K, Castro M, Hansel NN, Diette GB, Vonakis BM, Adkinson NF, Klanderman BJ, Senter-Sylvia J, Ziniti J, Lange C, Pastinen T, Raby BA
published in: Human molecular genetics
information resource reference: Mapping of numerous disease-associated expression polymorphisms in primary peripheral blood CD4+ lymphocytes. Hum Mol Genet. 2010 Dec 01; 19(23):4745-57.
journal title abbreviation: Hum Mol Genet
publication date: 2010-09-10T00:00:00
year: 2010
type: Academic Article
type: Article
type: Document
type: Information Resource

Testing for non-random mating: evidence for ancestry-related assortative mating in the Framingham heart study.
PubMed Identifier: 20842694
author list: Sebro R, Hoffman TJ, Lange C, Rogus JJ, Risch NJ
published in: Genetic epidemiology
information resource reference: Testing for non-random mating: evidence for ancestry-related assortative mating in the Framingham heart study. Genet Epidemiol. 2010 Nov; 34(7):674-9.
journal title abbreviation: Genet Epidemiol
publication date: 2010-11-01T00:00:00
year: 2010
type: Academic Article
type: Article
type: Document
type: Information Resource

Assessing the reproducibility of asthma candidate gene associations, using genome-wide data.
PubMed Identifier: 19264973
author list: Rogers AJ, Raby BA, Lasky-Su JA, Murphy A, Lazarus R, Klanderman BJ, Sylvia JS, Ziniti JP, Lange C, Celedón JC, Silverman EK, Weiss ST
published in: American journal of respiratory and critical care medicine
information resource reference: Assessing the reproducibility of asthma candidate gene associations, using genome-wide data. Am J Respir Crit Care Med. 2009 Jun 15; 179(12):1084-90.
journal title abbreviation: Am J Respir Crit Care Med
publication date: 2009-03-05T00:00:00
year: 2009
type: Academic Article
type: Article
type: Document
type: Information Resource

Bronchoalveolar lavage enzyme-linked immunospot for a rapid diagnosis of tuberculosis: a Tuberculosis Network European Trialsgroup study.
PubMed Identifier: 19590020
author list: Jafari C, Thijsen S, Sotgiu G, Goletti D, Domínguez Benítez JA, Losi M, Eberhardt R, Kirsten D, Kalsdorf B, Bossink A, Latorre I, Migliori GB, Strassburg A, Winteroll S, Greinert U, Richeldi L, Ernst M, Lange C
published in: American journal of respiratory and critical care medicine
information resource reference: Bronchoalveolar lavage enzyme-linked immunospot for a rapid diagnosis of tuberculosis: a Tuberculosis Network European Trialsgroup study. Am J Respir Crit Care Med. 2009 Oct 01; 180(7):666-73.
journal title abbreviation: Am J Respir Crit Care Med
publication date: 2009-07-09T00:00:00
year: 2009
type: Academic Article
type: Article
type: Document
type: Information Resource

Association of corticotropin-releasing hormone receptor-2 genetic variants with acute bronchodilator response in asthma.
PubMed Identifier: 18408560
author list: Poon AH, Tantisira KG, Litonjua AA, Lazarus R, Xu J, Lasky-Su J, Lima JJ, Irvin CG, Hanrahan JP, Lange C, Weiss ST
published in: Pharmacogenetics and genomics
information resource reference: Association of corticotropin-releasing hormone receptor-2 genetic variants with acute bronchodilator response in asthma. Pharmacogenet Genomics. 2008 May; 18(5):373-82.
journal title abbreviation: Pharmacogenet Genomics
publication date: 2008-05-01T00:00:00
year: 2008
type: Academic Article
type: Article
type: Document
type: Information Resource

On the frequency of copy number variants.
PubMed Identifier: 18689430
author list: Ionita-Laza I, Laird NM, Raby BA, Weiss ST, Lange C
published in: Bioinformatics (Oxford, England)
information resource reference: On the frequency of copy number variants. Bioinformatics. 2008 Oct 15; 24(20):2350-5.
journal title abbreviation: Bioinformatics
publication date: 2008-08-08T00:00:00
year: 2008
type: Academic Article
type: Article
type: Document
type: Information Resource

Asthma-susceptibility variants identified using probands in case-control and family-based analyses.
PubMed Identifier: 20698975
author list: Himes BE, Lasky-Su J, Wu AC, Wilk JB, Hunninghake GM, Klanderman B, Murphy AJ, Lazarus R, Soto-Quiros ME, Avila L, Celedón JC, Lange C, O'Connor GT, Raby BA, Silverman EK, Weiss ST
published in: BMC medical genetics
information resource reference: Asthma-susceptibility variants identified using probands in case-control and family-based analyses. BMC Med Genet. 2010 Aug 10; 11:122.
journal title abbreviation: BMC Med Genet
publication date: 2010-08-10T00:00:00
year: 2010
type: Academic Article
type: Article
type: Document
type: Information Resource

Association between schizophrenia and common variation in neurocan (NCAN), a genetic risk factor for bipolar disorder.
PubMed Identifier: 22497794
author list: Mühleisen TW, Mattheisen M, Strohmaier J, Degenhardt F, Priebe L, Schultz CC, Breuer R, Meier S, Hoffmann P, Rivandeneira F, Hofman A, Uitterlinden AG, Moebus S, Gieger C, Emeny R, Ladwig KH, Wichmann HE, Schwarz M, Kammerer-Ciernioch J, Schlösser RG, Nenadic I, Sauer H, Mössner R, Maier W, Rujescu D, Lange C, Ophoff RA, Schulze TG, Rietschel M, Nöthen MM, Cichon S
published in: Schizophrenia research
information resource reference: Association between schizophrenia and common variation in neurocan (NCAN), a genetic risk factor for bipolar disorder. Schizophr Res. 2012 Jun; 138(1):69-73.
journal title abbreviation: Schizophr Res
publication date: 2012-04-11T00:00:00
year: 2012
type: Academic Article
type: Article
type: Document
type: Information Resource

'Location, Location, Location': a spatial approach for rare variant analysis and an application to a study on non-syndromic cleft lip with or without cleft palate.
PubMed Identifier: 23044548
author list: Fier H, Won S, Prokopenko D, AlChawa T, Ludwig KU, Fimmers R, Silverman EK, Pagano M, Mangold E, Lange C
published in: Bioinformatics (Oxford, England)
information resource reference: 'Location, Location, Location': a spatial approach for rare variant analysis and an application to a study on non-syndromic cleft lip with or without cleft palate. Bioinformatics. 2012 Dec 01; 28(23):3027-33.
journal title abbreviation: Bioinformatics
publication date: 2012-10-08T00:00:00
year: 2012
type: Academic Article
type: Article
type: Document
type: Information Resource

A multivariate family-based association test using generalized estimating equations: FBAT-GEE.
PubMed Identifier: 12925516
author list: Lange C, Silverman EK, Xu X, Weiss ST, Laird NM
published in: Biostatistics (Oxford, England)
information resource reference: A multivariate family-based association test using generalized estimating equations: FBAT-GEE. Biostatistics. 2003 Apr; 4(2):195-206.
journal title abbreviation: Biostatistics
publication date: 2003-04-01T00:00:00
year: 2003
type: Academic Article
type: Article
type: Document
type: Information Resource

Genome-wide linkage of forced mid-expiratory flow in chronic obstructive pulmonary disease.
PubMed Identifier: 15347563
author list: DeMeo DL, Celedón JC, Lange C, Reilly JJ, Chapman HA, Sylvia JS, Speizer FE, Weiss ST, Silverman EK
published in: American journal of respiratory and critical care medicine
information resource reference: Genome-wide linkage of forced mid-expiratory flow in chronic obstructive pulmonary disease. Am J Respir Crit Care Med. 2004 Dec 15; 170(12):1294-301.
journal title abbreviation: Am J Respir Crit Care Med
publication date: 2004-09-03T00:00:00
year: 2004
type: Academic Article
type: Article
type: Document
type: Information Resource

Genome-wide meta-analyses of nonsyndromic cleft lip with or without cleft palate identify six new risk loci.
PubMed Identifier: 22863734
author list: Ludwig KU, Mangold E, Herms S, Nowak S, Reutter H, Paul A, Becker J, Herberz R, AlChawa T, Nasser E, Böhmer AC, Mattheisen M, Alblas MA, Barth S, Kluck N, Lauster C, Braumann B, Reich RH, Hemprich A, Pötzsch S, Blaumeiser B, Daratsianos N, Kreusch T, Murray JC, Marazita ML, Ruczinski I, Scott AF, Beaty TH, Kramer FJ, Wienker TF, Steegers-Theunissen RP, Rubini M, Mossey PA, Hoffmann P, Lange C, Cichon S, Propping P, Knapp M, Nöthen MM
published in: Nature genetics
information resource reference: Genome-wide meta-analyses of nonsyndromic cleft lip with or without cleft palate identify six new risk loci. Nat Genet. 2012 Sep; 44(9):968-71.
journal title abbreviation: Nat Genet
publication date: 2012-08-05T00:00:00
year: 2012
type: Academic Article
type: Article
type: Document
type: Information Resource