Burns, Melissa
eCommons Login: MAB45
first name: Melissa
last name: Burns
coauthor of: Bourgeois, Wallace
coauthor of: Harris, Marian
coauthor of: Neuberg, Donna
coauthor of: Sallan, Stephen
coauthor of: Place, Andrew
full name: Melissa Ann Burns, M.D.
has faculty rank: Assistant Professor
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Person ID: 17603
person in primary position: Assistant Professor of Pediatrics
physical neighbor: Baumeister, Susanne
physical neighbor: Collins, Natalie
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similar to: Look, A.
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type: Agent
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selected publications: Authorship 1794513
selected publications: Authorship 1734817
selected publications: Authorship 1636755
selected publications: Authorship 1570157
selected publications: Authorship 1449627
selected publications: Authorship 1268929
selected publications: Authorship 1323346
selected publications: Authorship 1292685
selected publications: Authorship 1205030
selected publications: Authorship 1178808
selected publications: Authorship 1111432
selected publications: Authorship 1058900
selected publications: Authorship 1838070
selected publications: Authorship 290050
selected publications: Authorship 384572
selected publications: Authorship 107079
research areas: Precursor T-Cell Lymphoblastic Leukemia-Lymphoma
research areas: Neoplasm, Residual
research areas: Hedgehog Proteins
research areas: Precursor Cell Lymphoblastic Leukemia-Lymphoma
research areas: Cell Transformation, Neoplastic
mailing address: 450 Brookline Ave
middle name or initial: Ann
positions: Assistant Professor of Pediatrics
phone: 617/355-6363
preferred title: Assistant Professor of Pediatrics

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Quantitative pathology in tissue MR spectroscopy based human prostate metabolomics.
PubMed Identifier: 15560717
author list: Burns MA, He W, Wu CL, Cheng LL
published in: Technology in cancer research & treatment
information resource reference: Quantitative pathology in tissue MR spectroscopy based human prostate metabolomics. Technol Cancer Res Treat. 2004 Dec; 3(6):591-8.
journal title abbreviation: Technol Cancer Res Treat
publication date: 2004-12-01T00:00:00
year: 2004
type: Academic Article
type: Article
type: Document
type: Information Resource

Reduction of spinning sidebands in proton NMR of human prostate tissue with slow high-resolution magic angle spinning.
PubMed Identifier: 15968646
author list: Burns MA, Taylor JL, Wu CL, Zepeda AG, Bielecki A, Cory D, Cheng LL
published in: Magnetic resonance in medicine
information resource reference: Reduction of spinning sidebands in proton NMR of human prostate tissue with slow high-resolution magic angle spinning. Magn Reson Med. 2005 Jul; 54(1):34-42.
journal title abbreviation: Magn Reson Med
publication date: 2005-07-01T00:00:00
year: 2005
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1058900
type: Authorship
author rank in publication: 1
linked author: Burns, Melissa
linked information resource: Hedgehog pathway mutations drive oncogenic transformation in high-risk T-cell acute lymphoblastic leukemia.

Hedgehog pathway mutations drive oncogenic transformation in high-risk T-cell acute lymphoblastic leukemia.
PubMed Identifier: 29654263
author list: Burns MA, Liao ZW, Yamagata N, Pouliot GP, Stevenson KE, Neuberg DS, Thorner AR, Ducar M, Silverman EA, Hunger SP, Loh ML, Winter SS, Dunsmore KP, Wood B, Devidas M, Harris MH, Silverman LB, Sallan SE, Gutierrez A
published in: Leukemia
information resource reference: Hedgehog pathway mutations drive oncogenic transformation in high-risk T-cell acute lymphoblastic leukemia. Leukemia. 2018 10; 32(10):2126-2137.
journal title abbreviation: Leukemia
publication date: 2018-03-20T00:00:00
year: 2018
type: Academic Article
type: Article
type: Document
type: Information Resource

Bourgeois, Wallace
eCommons Login: WB60
first name: Wallace
last name: Bourgeois
full name: Wallace Bourgeois, M.D.
has faculty rank: Instructor
Person ID: 170306
person in primary position: Instructor in Pediatrics
type: Agent
type: Person
preferred title: Instructor in Pediatrics

Authorship 107079
type: Authorship
author rank in publication: 1
linked author: Burns, Melissa
linked information resource: Quantitative pathology in tissue MR spectroscopy based human prostate metabolomics.

Authorship 1111432
type: Authorship
author rank in publication: 6
linked author: Burns, Melissa
linked information resource: PRC2 loss induces chemoresistance by repressing apoptosis in T cell acute lymphoblastic leukemia.

PRC2 loss induces chemoresistance by repressing apoptosis in T cell acute lymphoblastic leukemia.
PubMed Identifier: 30404791
author list: Ariës IM, Bodaar K, Karim SA, Chonghaile TN, Hinze L, Burns MA, Pfirrmann M, Degar J, Landrigan JT, Balbach S, Peirs S, Menten B, Isenhart R, Stevenson KE, Neuberg DS, Devidas M, Loh ML, Hunger SP, Teachey DT, Rabin KR, Winter SS, Dunsmore KP, Wood BL, Silverman LB, Sallan SE, Van Vlierberghe P, Orkin SH, Knoechel B, Letai AG, Gutierrez A
published in: The Journal of experimental medicine
information resource reference: PRC2 loss induces chemoresistance by repressing apoptosis in T cell acute lymphoblastic leukemia. J Exp Med. 2018 12 03; 215(12):3094-3114.
journal title abbreviation: J Exp Med
publication date: 2018-11-07T00:00:00
year: 2018
type: Academic Article
type: Article
type: Document
type: Information Resource

Neoplasm, Residual
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Cell Transformation, Neoplastic
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Precursor Cell Lymphoblastic Leukemia-Lymphoma
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number of authors: 479
number of publications: 1469
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Precursor T-Cell Lymphoblastic Leukemia-Lymphoma
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number of authors: 163
number of publications: 375
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Hedgehog Proteins
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MeSH semantic group name: Chemicals & Drugs
number of authors: 365
number of publications: 760
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Biostatistics
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Medicine
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Brigham and Women's Hospital
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Boston Children's Hospital
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Dana-Farber Cancer Institute
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Harvard T.H. Chan School of Public Health
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Massachusetts General Hospital
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Look, A.
eCommons Login: ATL1
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has faculty rank: Full Professor
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Place, Andrew
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Sallan, Stephen
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Neuberg, Donna
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photo: https://connects.catalyst.harvard.edu/Profiles/profile/Modules/CustomViewPersonGeneralInfo/PhotoHandler.ashx
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person in primary position: Senior Lecturer on Biostatistics, Emerita
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Vrooman, Lynda
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first name: Lynda
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DeAngelo, Daniel
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Baumeister, Susanne
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person in primary position: Assistant Professor of Pediatrics
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Collins, Natalie
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first name: Natalie
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person in primary position: Assistant Professor of Pediatrics
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Harris, Marian
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first name: Marian
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latitude: 42.33510370000000
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person in primary position: Assistant Professor of Pathology
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Luskin, Marlise
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first name: Marlise
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full name: Marlise Rachael Luskin, M.D.
has faculty rank: Associate Professor
latitude: 42.33510370000000
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person in primary position: Associate Professor of Medicine
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Langenau, David
eCommons Login: DML4
first name: David
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Aster, Jon
eCommons Login: JCA4
first name: Jon
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Person ID: 48586
person in primary position: Ramzi S. Cotran Professor of Pathology
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Kamihara, Junne
eCommons Login: JK24
first name: Junne
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person in primary position: Assistant Professor of Pediatrics
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Feraco, Angela
eCommons Login: AMF35
first name: Angela
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full name: Angela Marie Feraco, M.D.
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person in primary position: Assistant Professor of Pediatrics
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Authorship 1178808
type: Authorship
author rank in publication: 3
linked author: Burns, Melissa
linked information resource: Prohibitin is a prognostic marker and therapeutic target to block chemotherapy resistance in Wilms' tumor.

Prohibitin is a prognostic marker and therapeutic target to block chemotherapy resistance in Wilms' tumor.
PubMed Identifier: 31391345
author list: Ortiz MV, Ahmed S, Burns M, Henssen AG, Hollmann TJ, MacArthur I, Gunasekera S, Gaewsky L, Bradwin G, Ryan J, Letai A, He Y, Naranjo A, Chi YY, LaQuaglia M, Heaton T, Cifani P, Dome JS, Gadd S, Perlman E, Mullen E, Steen H, Kentsis A
published in: JCI insight
information resource reference: Prohibitin is a prognostic marker and therapeutic target to block chemotherapy resistance in Wilms' tumor. JCI Insight. 2019 08 08; 4(15).
journal title abbreviation: JCI Insight
publication date: 2019-08-08T00:00:00
year: 2019
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1205030
type: Authorship
author rank in publication: 6
linked author: Burns, Melissa
linked information resource: Fanconi-BRCA pathway mutations in childhood T-cell acute lymphoblastic leukemia.

Fanconi-BRCA pathway mutations in childhood T-cell acute lymphoblastic leukemia.
PubMed Identifier: 31721781
author list: Pouliot GP, Degar J, Hinze L, Kochupurakkal B, Vo CD, Burns MA, Moreau L, Ganesa C, Roderick J, Peirs S, Menten B, Loh ML, Hunger SP, Silverman LB, Harris MH, Stevenson KE, Weinstock DM, Weng AP, Van Vlierberghe P, D'Andrea AD, Gutierrez A
published in: PloS one
information resource reference: Fanconi-BRCA pathway mutations in childhood T-cell acute lymphoblastic leukemia. PLoS One. 2019; 14(11):e0221288.
journal title abbreviation: PLoS One
publication date: 2019-11-13T00:00:00
year: 2019
type: Academic Article
type: Article
type: Document
type: Information Resource

Professor of Pediatrics
is primary position: true
position in department: Pediatrics
position in division: DFCI
sort order: 1
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HR job title: Professor of Pediatrics
position in organization: Dana-Farber Cancer Institute

Assistant Professor of Pediatrics
is primary position: true
position in department: Pediatrics
position in division: Hematology/Oncology
sort order: 1
type: Position
HR job title: Assistant Professor of Pediatrics
position in organization: Dana-Farber Cancer Institute

Professor of Pathology
is primary position: true
position in department: Pathology
position in division: https://connects.catalyst.harvard.edu/Profiles/profile/1229413
sort order: 1
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HR job title: Professor of Pathology
position in organization: Massachusetts General Hospital

Authorship 1268929
type: Authorship
author rank in publication: 10
linked author: Burns, Melissa
linked information resource: Molecular basis of ETV6-mediated predisposition to childhood acute lymphoblastic leukemia.

Molecular basis of ETV6-mediated predisposition to childhood acute lymphoblastic leukemia.
PubMed Identifier: 32693409
author list: Nishii R, Baskin-Doerfler R, Yang W, Oak N, Zhao X, Yang W, Hoshitsuki K, Bloom M, Verbist K, Burns M, Li Z, Lin TN, Qian M, Moriyama T, Gastier-Foster JM, Rabin KR, Raetz E, Mullighan C, Pui CH, Yeoh AE, Zhang J, Metzger ML, Klco JM, Hunger SP, Newman S, Wu G, Loh ML, Nichols KE, Yang JJ
published in: Blood
information resource reference: Molecular basis of ETV6-mediated predisposition to childhood acute lymphoblastic leukemia. Blood. 2021 01 21; 137(3):364-373.
journal title abbreviation: Blood
publication date: 2021-01-21T00:00:00
year: 2021
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1292685
type: Authorship
author rank in publication: 1
linked author: Burns, Melissa
linked information resource: Identification of prognostic factors in childhood T-cell acute lymphoblastic leukemia: Results from DFCI ALL Consortium Protocols 05-001 and 11-001.

Identification of prognostic factors in childhood T-cell acute lymphoblastic leukemia: Results from DFCI ALL Consortium Protocols 05-001 and 11-001.
PubMed Identifier: 33026184
author list: Burns MA, Place AE, Stevenson KE, Gutiérrez A, Forrest S, Pikman Y, Vrooman LM, Harris MH, Hunt SK, O'Brien JE, Asselin BL, Athale UH, Clavell LA, Cole PD, Gennarini LM, Kahn JM, Kelly KM, Laverdiere C, Leclerc JM, Michon B, Schorin MA, Sulis ML, Welch JJG, Neuberg DS, Sallan SE, Silverman LB
published in: Pediatric blood & cancer
information resource reference: Identification of prognostic factors in childhood T-cell acute lymphoblastic leukemia: Results from DFCI ALL Consortium Protocols 05-001 and 11-001. Pediatr Blood Cancer. 2021 01; 68(1):e28719.
journal title abbreviation: Pediatr Blood Cancer
publication date: 2020-10-07T00:00:00
year: 2020
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1323346
type: Authorship
author rank in publication: 1
linked author: Burns, Melissa
linked information resource: Corrigendum.

Corrigendum.
PubMed Identifier: 33506554
author list: Burns MA, Place AE, Stevenson KE, Gutiérrez A, Forrest S, Pikman Y, Vrooman LM, Harris MH, Weinberg OK, Hunt SK, O'Brien JE, Asselin BL, Athale UH, Clavell LA, Cole PD, Gennarini LM, Kahn J, Kelly KM, Laverdiere C, Leclerc JM, Michon B, Schorin MA, Sulis ML, Welch JJG, Neuberg DS, Sallan SE, Silverman LB
published in: Pediatric blood & cancer
information resource reference: Corrigendum. Pediatr Blood Cancer. 2021 Mar; 68(3):e28885.
journal title abbreviation: Pediatr Blood Cancer
publication date: 2020-12-31T00:00:00
year: 2020
type: Academic Article
type: Article
type: Document
type: Information Resource

Assistant Professor of Pediatrics
is primary position: true
position in department: Pediatrics
position in division: Hematology/Oncology
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type: Position
HR job title: Assistant Professor of Pediatrics
position in organization: Dana-Farber Cancer Institute

Authorship 1449627
type: Authorship
author rank in publication: 6
linked author: Burns, Melissa
linked information resource: JAK3 mutations and mitochondrial apoptosis resistance in T-cell acute lymphoblastic leukemia.

JAK3 mutations and mitochondrial apoptosis resistance in T-cell acute lymphoblastic leukemia.
PubMed Identifier: 35411095
author list: Bodaar K, Yamagata N, Barthe A, Landrigan J, Chonghaile TN, Burns M, Stevenson KE, Devidas M, Loh ML, Hunger SP, Wood B, Silverman LB, Teachey DT, Meijerink JP, Letai A, Gutierrez A
published in: Leukemia
information resource reference: JAK3 mutations and mitochondrial apoptosis resistance in T-cell acute lymphoblastic leukemia. Leukemia. 2022 06; 36(6):1499-1507.
journal title abbreviation: Leukemia
publication date: 2022-04-11T00:00:00
year: 2022
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1570157
type: Authorship
author rank in publication: 10
linked author: Burns, Melissa
linked information resource: Outcome for Children and Young Adults With T-Cell ALL and Induction Failure in Contemporary Trials.

Outcome for Children and Young Adults With T-Cell ALL and Induction Failure in Contemporary Trials.
PubMed Identifier: 37487146
author list: Raetz EA, Rebora P, Conter V, Schrappe M, Devidas M, Escherich G, Imai C, De Moerloose B, Schmiegelow K, Burns MA, Elitzur S, Pieters R, Attarbaschi A, Yeoh A, Pui CH, Stary J, Cario G, Bodmer N, Moorman AV, Buldini B, Vora A, Valsecchi MG
published in: Journal of clinical oncology : official journal of the American Society of Clinical Oncology
information resource reference: Outcome for Children and Young Adults With T-Cell ALL and Induction Failure in Contemporary Trials. J Clin Oncol. 2023 11 10; 41(32):5025-5034.
journal title abbreviation: J Clin Oncol
publication date: 2023-07-24T00:00:00
year: 2023
type: Academic Article
type: Article
type: Document
type: Information Resource

Assistant Professor of Pediatrics
is primary position: true
position in department: Pediatrics
position in division: Hematology/Oncology
sort order: 1
type: Position
HR job title: Assistant Professor of Pediatrics
position in organization: Dana-Farber Cancer Institute

Activity of the MEK inhibitor trametinib in a patient with a BRAF mutation persisting from T-lymphoblastic lymphoma through lineage switch to CNS acute myeloid leukemia.
PubMed Identifier: 38532250
author list: Bourgeois W, Yang E, Chiarle R, Burns M
published in: Pediatric blood & cancer
information resource reference: Activity of the MEK inhibitor trametinib in a patient with a BRAF mutation persisting from T-lymphoblastic lymphoma through lineage switch to CNS acute myeloid leukemia. Pediatr Blood Cancer. 2024 Jun; 71(6):e30978.
journal title abbreviation: Pediatr Blood Cancer
publication date: 2024-03-26T00:00:00
year: 2024
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1636755
type: Authorship
author rank in publication: 4
linked author: Burns, Melissa
linked information resource: Activity of the MEK inhibitor trametinib in a patient with a BRAF mutation persisting from T-lymphoblastic lymphoma through lineage switch to CNS acute myeloid leukemia.

Instructor in Pediatrics
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position in division: Hematology/Oncology
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HR job title: Instructor in Pediatrics
position in organization: Dana-Farber Cancer Institute

Ramzi S. Cotran Professor of Pathology
is primary position: true
position in department: Pathology
position in division: https://connects.catalyst.harvard.edu/Profiles/profile/1229413
sort order: 1
type: Position
HR job title: Ramzi S. Cotran Professor of Pathology
position in organization: Brigham and Women's Hospital

Professor of Medicine
is primary position: true
position in department: Medicine
position in division: Oncology
sort order: 1
type: Position
HR job title: Professor of Medicine
position in organization: Dana-Farber Cancer Institute

Assistant Professor of Pediatrics
is primary position: true
position in department: Pediatrics
position in division: Hematology/Oncology
sort order: 1
type: Position
HR job title: Assistant Professor of Pediatrics
position in organization: Dana-Farber Cancer Institute

Assistant Professor of Pediatrics
is primary position: true
position in department: Pediatrics
position in division: Hematology/Oncology
sort order: 1
type: Position
HR job title: Assistant Professor of Pediatrics
position in organization: Dana-Farber Cancer Institute

Assistant Professor of Pediatrics
is primary position: true
position in department: Pediatrics
position in division: Hematology/Oncology
sort order: 1
type: Position
HR job title: Assistant Professor of Pediatrics
position in organization: Dana-Farber Cancer Institute

Associate Professor of Medicine
is primary position: true
position in department: Medicine
position in division: Oncology
sort order: 1
type: Position
HR job title: Associate Professor of Medicine
position in organization: Dana-Farber Cancer Institute

Assistant Professor of Pediatrics
is primary position: true
position in department: Pediatrics
position in division: Hematology/Oncology
sort order: 1
type: Position
HR job title: Assistant Professor of Pediatrics
position in organization: Dana-Farber Cancer Institute

Authorship 1734817
type: Authorship
author rank in publication: 7
linked author: Burns, Melissa
linked information resource: https://connects.catalyst.harvard.edu/Profiles/profile/279588870

https://connects.catalyst.harvard.edu/Profiles/profile/279588870
PubMed Identifier: 39937083
author list: Shah NN, Schafer ES, Chi YY, Malvar J, Heym KM, Place AE, Burns M, Chang BH, Slone T, Verma A, Gossai N, Shaw PH, Burke MJ, Hermiston M, Schore RJ, Cooper T, Pauly M, Rushing T, Jarosinski P, Florendo E, Yates B, Widemann BC, Peer CJ, Figg WD, Silverman LB, Bhojwani D, Wayne AS
published in: Pediatric blood & cancer
information resource reference: Vincristine Sulfate Liposome Injection With Combination Chemotherapy for Children, Adolescents, and Young Adults With Relapsed Acute Lymphoblastic Leukemia: A Therapeutic Advances in Childhood Leukemia and Lymphoma Consortium Trial. Pediatr Blood Cancer. 2025 May; 72(5):e31584.
journal title abbreviation: Pediatr Blood Cancer
publication date: 2025-02-12T00:00:00
year: 2025
type: Academic Article
type: Article
type: Document
type: Information Resource
label: Vincristine Sulfate Liposome Injection With Combination Chemotherapy for Children, Adolescents, and Young Adults With Relapsed Acute Lymphoblastic Leukemia: A Therapeutic Advances in Childhood Leukemia and Lymphoma Consortium Trial.

Authorship 1794513
type: Authorship
author rank in publication: 6
linked author: Burns, Melissa
linked information resource: CSF metabolomic signature during therapy for childhood acute lymphoblastic leukemia predicts subsequent working memory impairment.

Authorship 1838070
type: Authorship
author rank in publication: 9
linked author: Burns, Melissa
linked information resource: Genomic DNA transposition induced by human PGBD5.

Genomic DNA transposition induced by human PGBD5.
PubMed Identifier: 26406119
author list: Henssen AG, Henaff E, Jiang E, Eisenberg AR, Carson JR, Villasante CM, Ray M, Still E, Burns M, Gandara J, Feschotte C, Mason CE, Kentsis A
published in: eLife
information resource reference: Genomic DNA transposition induced by human PGBD5. Elife. 2015 Sep 25; 4.
journal title abbreviation: Elife
publication date: 2015-09-25T00:00:00
year: 2015
type: Academic Article
type: Article
type: Document
type: Information Resource

CSF metabolomic signature during therapy for childhood acute lymphoblastic leukemia predicts subsequent working memory impairment.
PubMed Identifier: 41469545
author list: Willekens J, Ramjan S, Sands SA, Park Y, K C N, Burns MA, Welch JJG, Kahn J, Kelly KM, Tran TH, Michon B, Gennarini L, Place A, Silverman LB, Cole PD
published in: Molecular medicine (Cambridge, Mass.)
information resource reference: CSF metabolomic signature during therapy for childhood acute lymphoblastic leukemia predicts subsequent working memory impairment. Mol Med. 2025 Dec 30; 32(1):12.
journal title abbreviation: Mol Med
publication date: 2025-12-30T00:00:00
year: 2025
type: Academic Article
type: Article
type: Document
type: Information Resource

Professor of Pediatrics
is primary position: true
position in department: Pediatrics
position in division: Hematology/Oncology
sort order: 1
type: Position
HR job title: Professor of Pediatrics
position in organization: Dana-Farber Cancer Institute

Senior Lecturer on Biostatistics, Emerita
is primary position: true
position in department: Biostatistics
position in division: https://connects.catalyst.harvard.edu/Profiles/profile/1229413
sort order: 1
type: Position
HR job title: Senior Lecturer on Biostatistics, Emerita
position in organization: Harvard T.H. Chan School of Public Health

Assistant Professor of Pathology
is primary position: true
position in department: Pathology
position in division: https://connects.catalyst.harvard.edu/Profiles/profile/1229413
sort order: 1
type: Position
HR job title: Assistant Professor of Pathology
position in organization: Boston Children's Hospital

Authorship 384572
type: Authorship
author rank in publication: 2
linked author: Burns, Melissa
linked information resource: Metabolic characterization of human prostate cancer with tissue magnetic resonance spectroscopy.

DFCI
type: Division
type: Organization

Authorship 290050
type: Authorship
author rank in publication: 1
linked author: Burns, Melissa
linked information resource: Reduction of spinning sidebands in proton NMR of human prostate tissue with slow high-resolution magic angle spinning.

Assistant Professor
sort order: 2
type: Faculty Rank

Associate Professor
sort order: 1
type: Faculty Rank

Full Professor
sort order: 0
type: Faculty Rank

Instructor
sort order: 4
type: Faculty Rank

450 Brookline Ave
type: Address
address line 1: Dana-Farber Cancer Institute
address line 2: Da3-jfc
address line 3: 450 Brookline Ave
city: Boston
postal code: 02215
state or province: MA

Metabolic characterization of human prostate cancer with tissue magnetic resonance spectroscopy.
PubMed Identifier: 15833828
author list: Cheng LL, Burns MA, Taylor JL, He W, Halpern EF, McDougal WS, Wu CL
published in: Cancer research
information resource reference: Metabolic characterization of human prostate cancer with tissue magnetic resonance spectroscopy. Cancer Res. 2005 Apr 15; 65(8):3030-4.
journal title abbreviation: Cancer Res
publication date: 2005-04-15T00:00:00
year: 2005
type: Academic Article
type: Article
type: Document
type: Information Resource