Poznansky, Mark
eCommons Login: MP2
first name: Mark
last name: Poznansky
coauthor of: Reeves, Patrick
coauthor of: Kashiwagi, Satoshi
coauthor of: Sirbulescu, Ruxandra
coauthor of: Raju Paul, Susan
coauthor of: Gelfand, Jeffrey
full name: Mark Poznansky, M.B.,Ch.B., Ph.D.
has faculty rank: Full Professor
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Person ID: 16018
person in primary position: Professor of Medicine
physical neighbor: Dong, Krista
physical neighbor: El-Khoury, Joseph
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physical neighbor: Shioda, Toshihiro
similar to: Barouch, Dan
similar to: Sodroski, Joseph
similar to: Markmann, James
similar to: Fiorina, Paolo
similar to: Bonner-Weir, Susan
type: Agent
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selected publications: Authorship 1783752
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Authorship 1051871
type: Authorship
author rank in publication: 16
linked author: Poznansky, Mark
linked information resource: AMD3100 Augments the Efficacy of Mesothelin-Targeted, Immune-Activating VIC-008 in Mesothelioma by Modulating Intratumoral Immunosuppression.

AMD3100 Augments the Efficacy of Mesothelin-Targeted, Immune-Activating VIC-008 in Mesothelioma by Modulating Intratumoral Immunosuppression.
PubMed Identifier: 29511032
author list: Li B, Zeng Y, Reeves PM, Ran C, Liu Q, Qu X, Liang Y, Liu Z, Yuan J, Leblanc PR, Ye Z, Sluder AE, Gelfand JA, Brauns TA, Chen H, Poznansky MC
published in: Cancer immunology research
information resource reference: AMD3100 Augments the Efficacy of Mesothelin-Targeted, Immune-Activating VIC-008 in Mesothelioma by Modulating Intratumoral Immunosuppression. Cancer Immunol Res. 2018 05; 6(5):539-551.
journal title abbreviation: Cancer Immunol Res
publication date: 2018-03-06T00:00:00
year: 2018
type: Academic Article
type: Article
type: Document
type: Information Resource

Patients unaware of their HIV status present to inner city accident and emergency department with respiratory complications.
PubMed Identifier: 9315932
author list: Landau R, Coker R, Vermeulen E, Touquet R, Fothergill J, Poznansky MC
published in: Journal of accident & emergency medicine
information resource reference: Patients unaware of their HIV status present to inner city accident and emergency department with respiratory complications. J Accid Emerg Med. 1997 Sep; 14(5):304-6.
journal title abbreviation: J Accid Emerg Med
publication date: 1997-09-01T00:00:00
year: 1997
type: Academic Article
type: Article
type: Document
type: Information Resource

https://connects.catalyst.harvard.edu/Profiles/profile/1015368
PubMed Identifier: 10543615
author list: Poznansky MC, La Vecchio J, Silva-Arietta S, Porter-Brooks J, Brody K, Olszak IT, Adams GB, Ramstedt U, Marasco WA, Scadden DT
published in: Human gene therapy
information resource reference: Inhibition of human immunodeficiency virus replication and growth advantage of CD4+ T cells and monocytes derived from CD34+ cells transduced with an intracellular antibody directed against human immunodeficiency virus type 1 Tat. Hum Gene Ther. 1999 Oct 10; 10(15):2505-14.
journal title abbreviation: Hum Gene Ther
publication date: 1999-10-10T00:00:00
year: 1999
type: Academic Article
type: Article
type: Document
type: Information Resource
label: Inhibition of human immunodeficiency virus replication and growth advantage of CD4+ T cells and monocytes derived from CD34+ cells transduced with an intracellular antibody directed against human immunodeficiency virus type 1 Tat.

T-lymphocyte development and models of thymopoietic reconstitution.
PubMed Identifier: 12791073
author list: Robertson P, Poznansky MC
published in: Transplant infectious disease : an official journal of the Transplantation Society
information resource reference: T-lymphocyte development and models of thymopoietic reconstitution. Transpl Infect Dis. 2003 Mar; 5(1):38-42.
journal title abbreviation: Transpl Infect Dis
publication date: 2003-03-01T00:00:00
year: 2003
type: Academic Article
type: Article
type: Document
type: Information Resource

The difference between human C3F and C3S results from a single amino acid change from an asparagine to an aspartate residue at position 1216 on the alpha-chain of the complement component, C3.
PubMed Identifier: 2473125
author list: Poznansky MC, Clissold PM, Lachmann PJ
published in: Journal of immunology (Baltimore, Md. : 1950)
information resource reference: The difference between human C3F and C3S results from a single amino acid change from an asparagine to an aspartate residue at position 1216 on the alpha-chain of the complement component, C3. J Immunol. 1989 Aug 15; 143(4):1254-8.
journal title abbreviation: J Immunol
publication date: 1989-08-15T00:00:00
year: 1989
type: Academic Article
type: Article
type: Document
type: Information Resource

Migration of antigen-specific T cells away from CXCR4-binding human immunodeficiency virus type 1 gp120.
PubMed Identifier: 15113900
author list: Brainard DM, Tharp WG, Granado E, Miller N, Trocha AK, Ren XH, Conrad B, Terwilliger EF, Wyatt R, Walker BD, Poznansky MC
published in: Journal of virology
information resource reference: Migration of antigen-specific T cells away from CXCR4-binding human immunodeficiency virus type 1 gp120. J Virol. 2004 May; 78(10):5184-93.
journal title abbreviation: J Virol
publication date: 2004-05-01T00:00:00
year: 2004
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1065551
type: Authorship
author rank in publication: 20
linked author: Poznansky, Mark
linked information resource: Epigenetic Regulation of CXCL12 Plays a Critical Role in Mediating Tumor Progression and the Immune Response In Osteosarcoma.

Epigenetic Regulation of CXCL12 Plays a Critical Role in Mediating Tumor Progression and the Immune Response In Osteosarcoma.
PubMed Identifier: 29735547
author list: Li B, Wang Z, Wu H, Xue M, Lin P, Wang S, Lin N, Huang X, Pan W, Liu M, Yan X, Qu H, Sun L, Li H, Wu Y, Teng W, Wang Z, Zhou X, Chen H, Poznansky MC, Ye Z
published in: Cancer research
information resource reference: Epigenetic Regulation of CXCL12 Plays a Critical Role in Mediating Tumor Progression and the Immune Response In Osteosarcoma. Cancer Res. 2018 07 15; 78(14):3938-3953.
journal title abbreviation: Cancer Res
publication date: 2018-05-07T00:00:00
year: 2018
type: Academic Article
type: Article
type: Document
type: Information Resource

Reverse leukocyte migration can be attractive or repulsive.
PubMed Identifier: 18468440
author list: Huttenlocher A, Poznansky MC
published in: Trends in cell biology
information resource reference: Reverse leukocyte migration can be attractive or repulsive. Trends Cell Biol. 2008 Jun; 18(6):298-306.
journal title abbreviation: Trends Cell Biol
publication date: 2008-05-09T00:00:00
year: 2008
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1067462
type: Authorship
author rank in publication: 23
linked author: Poznansky, Mark
linked information resource: Report of the Key Opinion Leaders Meeting on Stem Cell-derived Beta Cells.

Report of the Key Opinion Leaders Meeting on Stem Cell-derived Beta Cells.
PubMed Identifier: 29781950
author list: Odorico J, Markmann J, Melton D, Greenstein J, Hwa A, Nostro C, Rezania A, Oberholzer J, Pipeleers D, Yang L, Cowan C, Huangfu D, Egli D, Ben-David U, Vallier L, Grey ST, Tang Q, Roep B, Ricordi C, Naji A, Orlando G, Anderson DG, Poznansky M, Ludwig B, Tomei A, Greiner DL, Graham M, Carpenter M, Migliaccio G, D'Amour K, Hering B, Piemonti L, Berney T, Rickels M, Kay T, Adams A
published in: Transplantation
information resource reference: Report of the Key Opinion Leaders Meeting on Stem Cell-derived Beta Cells. Transplantation. 2018 08; 102(8):1223-1229.
journal title abbreviation: Transplantation
publication date: 2018-08-01T00:00:00
year: 2018
type: Academic Article
type: Article
type: Document
type: Information Resource

Generation of a tissue-engineered thymic organoid.
PubMed Identifier: 17876092
author list: Vianello F, Poznansky MC
published in: Methods in molecular biology (Clifton, N.J.)
information resource reference: Generation of a tissue-engineered thymic organoid. Methods Mol Biol. 2007; 380:163-70.
journal title abbreviation: Methods Mol Biol
publication date: 2007-01-01T00:00:00
year: 2007
type: Academic Article
type: Article
type: Document
type: Information Resource

Active movement of T cells away from a chemokine.
PubMed Identifier: 10802710
author list: Poznansky MC, Olszak IT, Foxall R, Evans RH, Luster AD, Scadden DT
published in: Nature medicine
information resource reference: Active movement of T cells away from a chemokine. Nat Med. 2000 May; 6(5):543-8.
journal title abbreviation: Nat Med
publication date: 2000-05-01T00:00:00
year: 2000
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 107467
type: Authorship
author rank in publication: 5
linked author: Poznansky, Mark
linked information resource: HIV-1 envelope protein gp120 is present at high concentrations in secondary lymphoid organs of individuals with chronic HIV-1 infection.

Prevalence of HIV infection in patients attending an inner city accident and emergency department.
PubMed Identifier: 8148714
author list: Poznansky MC, Torkington J, Turner G, Bankes MJ, Parry JV, Connell JA, Touquet R, Weber J
published in: BMJ (Clinical research ed.)
information resource reference: Prevalence of HIV infection in patients attending an inner city accident and emergency department. BMJ. 1994 Mar 05; 308(6929):636.
journal title abbreviation: BMJ
publication date: 1994-03-05T00:00:00
year: 1994
type: Academic Article
type: Article
type: Document
type: Information Resource

The efficacy of T cell-mediated immune responses is reduced by the envelope protein of the chimeric HIV-1/SIV-KB9 virus in vivo.
PubMed Identifier: 18832708
author list: Stevceva L, Yoon V, Carville A, Pacheco B, Santosuosso M, Korioth-Schmitz B, Mansfield K, Poznansky MC
published in: Journal of immunology (Baltimore, Md. : 1950)
information resource reference: The efficacy of T cell-mediated immune responses is reduced by the envelope protein of the chimeric HIV-1/SIV-KB9 virus in vivo. J Immunol. 2008 Oct 15; 181(8):5510-21.
journal title abbreviation: J Immunol
publication date: 2008-10-15T00:00:00
year: 2008
type: Academic Article
type: Article
type: Document
type: Information Resource

Experience of HIV disease in a London District General Hospital.
PubMed Identifier: 7727583
author list: Coker RJ, Desmond N, Poznansky M, Smith C, Shafi MS, Bell D, Riordan JF, Murphy S
published in: International journal of STD & AIDS
information resource reference: Experience of HIV disease in a London District General Hospital. Int J STD AIDS. 1995 Jan-Feb; 6(1):47-9.
journal title abbreviation: Int J STD AIDS
publication date: 1995-01-01T00:00:00
year: 1995
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1087819
type: Authorship
author rank in publication: 8
linked author: Poznansky, Mark
linked information resource: Correction: Ruxolitinib sensitizes ovarian cancer to reduced dose Taxol, limits tumor growth and improves survival in immune competent mice.

Correction: Ruxolitinib sensitizes ovarian cancer to reduced dose Taxol, limits tumor growth and improves survival in immune competent mice.
PubMed Identifier: 30101001
author list: Reeves PM, Abbaslou MA, Kools FRW, Vutipongsatorn K, Tong X, Gavegnano C, Schinazi RF, Poznansky MC
published in: Oncotarget
information resource reference: Correction: Ruxolitinib sensitizes ovarian cancer to reduced dose Taxol, limits tumor growth and improves survival in immune competent mice. Oncotarget. 2018 07 13; 9(54):30472.
journal title abbreviation: Oncotarget
publication date: 2018-07-13T00:00:00
year: 2018
type: Academic Article
type: Article
type: Document
type: Information Resource

Dynamic alterations in chemokine gradients induce transendothelial shuttling of human T cells under physiologic shear conditions.
PubMed Identifier: 19797295
author list: Lee JY, Buzney CD, Poznansky MC, Sackstein R
published in: Journal of leukocyte biology
information resource reference: Dynamic alterations in chemokine gradients induce transendothelial shuttling of human T cells under physiologic shear conditions. J Leukoc Biol. 2009 Dec; 86(6):1285-94.
journal title abbreviation: J Leukoc Biol
publication date: 2009-12-01T00:00:00
year: 2009
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1089970
type: Authorship
author rank in publication: 4
linked author: Poznansky, Mark
linked information resource: Harnessing CXCL12 signaling to protect and preserve functional ß-cell mass and for cell replacement in type 1 diabetes.

Authorship 1090756
type: Authorship
author rank in publication: 1
linked author: Poznansky, Mark
linked information resource: Enzyme-protein conjugates: new possibilities for enzyme therapy.

Enzyme-protein conjugates: new possibilities for enzyme therapy.
PubMed Identifier: 6353439
author list: Poznansky MJ
published in: Pharmacology & therapeutics
information resource reference: Enzyme-protein conjugates: new possibilities for enzyme therapy. Pharmacol Ther. 1983; 21(1):53-76.
journal title abbreviation: Pharmacol Ther
publication date: 1983-01-01T00:00:00
year: 1983
type: Academic Article
type: Article
type: Document
type: Information Resource

Harnessing CXCL12 signaling to protect and preserve functional ß-cell mass and for cell replacement in type 1 diabetes.
PubMed Identifier: 30149101
author list: Alagpulinsa DA, Cao JJL, Sobell D, Poznansky MC
published in: Pharmacology & therapeutics
information resource reference: Harnessing CXCL12 signaling to protect and preserve functional ß-cell mass and for cell replacement in type 1 diabetes. Pharmacol Ther. 2019 01; 193:63-74.
journal title abbreviation: Pharmacol Ther
publication date: 2018-08-24T00:00:00
year: 2018
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1091587
type: Authorship
author rank in publication: 14
linked author: Poznansky, Mark
linked information resource: A pilot clinical trial of a near-infrared laser vaccine adjuvant: safety, tolerability, and cutaneous immune cell trafficking.

A pilot clinical trial of a near-infrared laser vaccine adjuvant: safety, tolerability, and cutaneous immune cell trafficking.
PubMed Identifier: 30192655
author list: Gelfand JA, Nazarian RM, Kashiwagi S, Brauns T, Martin B, Kimizuka Y, Korek S, Botvinick E, Elkins K, Thomas L, Locascio J, Parry B, Kelly KM, Poznansky MC
published in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology
information resource reference: A pilot clinical trial of a near-infrared laser vaccine adjuvant: safety, tolerability, and cutaneous immune cell trafficking. FASEB J. 2019 02; 33(2):3074-3081.
journal title abbreviation: FASEB J
publication date: 2018-09-07T00:00:00
year: 2018
type: Academic Article
type: Article
type: Document
type: Information Resource

Advantages in the use of L-asparaginase-albumin polymer as an antitumor agent.
PubMed Identifier: 6895861
author list: Poznansky MJ, Shandling M, Salkie MA, Elliott JF, Lau E
published in: Cancer research
information resource reference: Advantages in the use of L-asparaginase-albumin polymer as an antitumor agent. Cancer Res. 1982 Mar; 42(3):1020-5.
journal title abbreviation: Cancer Res
publication date: 1982-03-01T00:00:00
year: 1982
type: Academic Article
type: Article
type: Document
type: Information Resource

Physicians' experience and survival in patients with AIDS.
PubMed Identifier: 8668216
author list: Coker RJ, Poznansky MC
published in: The New England journal of medicine
information resource reference: Physicians' experience and survival in patients with AIDS. N Engl J Med. 1996 Aug 01; 335(5):349; author reply 350-1.
journal title abbreviation: N Engl J Med
publication date: 1996-08-01T00:00:00
year: 1996
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1106446
type: Authorship
author rank in publication: 6
linked author: Poznansky, Mark
linked information resource: Standardized guinea pig model for Q fever vaccine reactogenicity.

Standardized guinea pig model for Q fever vaccine reactogenicity.
PubMed Identifier: 30312355
author list: Baeten LA, Podell BK, Sluder AE, Garritsen A, Bowen RA, Poznansky MC
published in: PloS one
information resource reference: Standardized guinea pig model for Q fever vaccine reactogenicity. PLoS One. 2018; 13(10):e0205882.
journal title abbreviation: PLoS One
publication date: 2018-10-12T00:00:00
year: 2018
type: Academic Article
type: Article
type: Document
type: Information Resource

Efficiency of a high-titer retroviral vector for gene transfer into skeletal myoblasts.
PubMed Identifier: 9451039
author list: el Oakley RM, Brand NJ, Burton PB, McMullen MC, Adams GB, Poznansky MC, Barton PJ, Yacoub MH
published in: The Journal of thoracic and cardiovascular surgery
information resource reference: Efficiency of a high-titer retroviral vector for gene transfer into skeletal myoblasts. J Thorac Cardiovasc Surg. 1998 Jan; 115(1):1-8.
journal title abbreviation: J Thorac Cardiovasc Surg
publication date: 1998-01-01T00:00:00
year: 1998
type: Academic Article
type: Article
type: Document
type: Information Resource

Correlation of CXCL12 expression and FoxP3+ cell infiltration with human papillomavirus infection and clinicopathological progression of cervical cancer.
PubMed Identifier: 19808652
author list: Jaafar F, Righi E, Lindstrom V, Linton C, Nohadani M, Van Noorden S, Lloyd T, Poznansky J, Stamp G, Dina R, Coleman DV, Poznansky MC
published in: The American journal of pathology
information resource reference: Correlation of CXCL12 expression and FoxP3+ cell infiltration with human papillomavirus infection and clinicopathological progression of cervical cancer. Am J Pathol. 2009 Oct; 175(4):1525-35.
journal title abbreviation: Am J Pathol
publication date: 2009-10-01T00:00:00
year: 2009
type: Academic Article
type: Article
type: Document
type: Information Resource

CXCL12/CXCR4 blockade induces multimodal antitumor effects that prolong survival in an immunocompetent mouse model of ovarian cancer.
PubMed Identifier: 21742774
author list: Righi E, Kashiwagi S, Yuan J, Santosuosso M, Leblanc P, Ingraham R, Forbes B, Edelblute B, Collette B, Xing D, Kowalski M, Mingari MC, Vianello F, Birrer M, Orsulic S, Dranoff G, Poznansky MC
published in: Cancer research
information resource reference: CXCL12/CXCR4 blockade induces multimodal antitumor effects that prolong survival in an immunocompetent mouse model of ovarian cancer. Cancer Res. 2011 Aug 15; 71(16):5522-5534.
journal title abbreviation: Cancer Res
publication date: 2011-07-08T00:00:00
year: 2011
type: Academic Article
type: Article
type: Document
type: Information Resource

Microbiology
type: Department
type: Organization

HIV positive patients first presenting with an AIDS defining illness: characteristics and survival.
PubMed Identifier: 7613426
author list: Poznansky MC, Coker R, Skinner C, Hill A, Bailey S, Whitaker L, Renton A, Weber J
published in: BMJ (Clinical research ed.)
information resource reference: HIV positive patients first presenting with an AIDS defining illness: characteristics and survival. BMJ. 1995 Jul 15; 311(6998):156-8.
journal title abbreviation: BMJ
publication date: 1995-07-15T00:00:00
year: 1995
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1114084
type: Authorship
author rank in publication: 14
linked author: Poznansky, Mark
linked information resource: Brief Exposure of Skin to Near-Infrared Laser Modulates Mast Cell Function and Augments the Immune Response.

Brief Exposure of Skin to Near-Infrared Laser Modulates Mast Cell Function and Augments the Immune Response.
PubMed Identifier: 30420435
author list: Kimizuka Y, Katagiri W, Locascio JJ, Shigeta A, Sasaki Y, Shibata M, Morse K, Sîrbulescu RF, Miyatake M, Reeves P, Suematsu M, Gelfand J, Brauns T, Poznansky MC, Tsukada K, Kashiwagi S
published in: Journal of immunology (Baltimore, Md. : 1950)
information resource reference: Brief Exposure of Skin to Near-Infrared Laser Modulates Mast Cell Function and Augments the Immune Response. J Immunol. 2018 12 15; 201(12):3587-3603.
journal title abbreviation: J Immunol
publication date: 2018-11-12T00:00:00
year: 2018
type: Academic Article
type: Article
type: Document
type: Information Resource

Naive and memory CD4? T cells in HIV eradication and immunization.
PubMed Identifier: 22696498
author list: Zhang J, Poznansky M, Crumpacker C
published in: The Journal of infectious diseases
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Changing patterns of presentations of patients with HIV-related disease at a tertiary referral centre and its implications for physician training.
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author list: Segal R, Poznansky MC, Connors L, Sands K, Barlam T
published in: International journal of STD & AIDS
information resource reference: Changing patterns of presentations of patients with HIV-related disease at a tertiary referral centre and its implications for physician training. Int J STD AIDS. 2001 Jul; 12(7):453-9.
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A CXCR4-dependent chemorepellent signal contributes to the emigration of mature single-positive CD4 cells from the fetal thymus.
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author list: Vianello F, Kraft P, Mok YT, Hart WK, White N, Poznansky MC
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information resource reference: A CXCR4-dependent chemorepellent signal contributes to the emigration of mature single-positive CD4 cells from the fetal thymus. J Immunol. 2005 Oct 15; 175(8):5115-25.
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linked information resource: Alginate-microencapsulation of human stem cell-derived ß cells with CXCL12 prolongs their survival and function in immunocompetent mice without systemic immunosuppression.

Alginate-microencapsulation of human stem cell-derived ß cells with CXCL12 prolongs their survival and function in immunocompetent mice without systemic immunosuppression.
PubMed Identifier: 30748094
author list: Alagpulinsa DA, Cao JJL, Driscoll RK, Sîrbulescu RF, Penson MFE, Sremac M, Engquist EN, Brauns TA, Markmann JF, Melton DA, Poznansky MC
published in: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons
information resource reference: Alginate-microencapsulation of human stem cell-derived ß cells with CXCL12 prolongs their survival and function in immunocompetent mice without systemic immunosuppression. Am J Transplant. 2019 07; 19(7):1930-1940.
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linked information resource: Efficient generation of human T cells from a tissue-engineered thymic organoid.

Authorship 1137253
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linked information resource: Promiscuous Coxiella burnetii CD4 Epitope Clusters Associated With Human Recall Responses Are Candidates for a Novel T-Cell Targeted Multi-Epitope Q Fever Vaccine.

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linked information resource: Dual blockade of CXCL12-CXCR4 and PD-1-PD-L1 pathways prolongs survival of ovarian tumor-bearing mice by prevention of immunosuppression in the tumor microenvironment.

Dual blockade of CXCL12-CXCR4 and PD-1-PD-L1 pathways prolongs survival of ovarian tumor-bearing mice by prevention of immunosuppression in the tumor microenvironment.
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author list: Zeng Y, Li B, Liang Y, Reeves PM, Qu X, Ran C, Liu Q, Callahan MV, Sluder AE, Gelfand JA, Chen H, Poznansky MC
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information resource reference: Dual blockade of CXCL12-CXCR4 and PD-1-PD-L1 pathways prolongs survival of ovarian tumor-bearing mice by prevention of immunosuppression in the tumor microenvironment. FASEB J. 2019 05; 33(5):6596-6608.
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Promiscuous Coxiella burnetii CD4 Epitope Clusters Associated With Human Recall Responses Are Candidates for a Novel T-Cell Targeted Multi-Epitope Q Fever Vaccine.
PubMed Identifier: 30828331
author list: Scholzen A, Richard G, Moise L, Baeten LA, Reeves PM, Martin WD, Brauns TA, Boyle CM, Raju Paul S, Bucala R, Bowen RA, Garritsen A, De Groot AS, Sluder AE, Poznansky MC
published in: Frontiers in immunology
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Islets of Langerhans Transplantation
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MGH Cancer Center Research
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Authorship 1144347
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linked information resource: Intraparenchymal Application of Mature B Lymphocytes Improves Structural and Functional Outcome after Contusion Traumatic Brain Injury.

Intraparenchymal Application of Mature B Lymphocytes Improves Structural and Functional Outcome after Contusion Traumatic Brain Injury.
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author list: Sîrbulescu RF, Chung JY, Edmiston WJ, Poznansky SA, Poznansky MC, Whalen MJ
published in: Journal of neurotrauma
information resource reference: Intraparenchymal Application of Mature B Lymphocytes Improves Structural and Functional Outcome after Contusion Traumatic Brain Injury. J Neurotrauma. 2019 09 01; 36(17):2579-2589.
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Alginates
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linked information resource: Safety of intramyocardial injection of autologous bone marrow cells to treat myocardial ischemia in pigs.

Q Fever
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Chemokine CXCL12
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Coxiella burnetii
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Emeritus
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Gelfand, Jeffrey
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Kashiwagi, Satoshi
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Barouch, Dan
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linked information resource: Preliminary Studies of the Impact of CXCL12 on the Foreign Body Reaction to Pancreatic Islets Microencapsulated in Alginate in Nonhuman Primates.

Preliminary Studies of the Impact of CXCL12 on the Foreign Body Reaction to Pancreatic Islets Microencapsulated in Alginate in Nonhuman Primates.
PubMed Identifier: 31165082
author list: Sremac M, Lei J, Penson MFE, Schuetz C, Lakey JRT, Papas KK, Varde PS, Hering B, de Vos P, Brauns T, Markmann J, Poznansky MC
published in: Transplantation direct
information resource reference: Preliminary Studies of the Impact of CXCL12 on the Foreign Body Reaction to Pancreatic Islets Microencapsulated in Alginate in Nonhuman Primates. Transplant Direct. 2019 May; 5(5):e447.
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Juelg, Boris
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Sodroski, Joseph
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Reeves, Patrick
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Bonner-Weir, Susan
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El-Khoury, Joseph
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Authorship 1170325
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linked information resource: CD90low MSCs modulate intratumoral immunity to confer antitumor activity in a mouse model of ovarian cancer.

CD90low MSCs modulate intratumoral immunity to confer antitumor activity in a mouse model of ovarian cancer.
PubMed Identifier: 31320999
author list: Zeng Y, Li B, Li T, Liu W, Ran C, Penson RT, Poznansky MC, Du Y, Chen H
published in: Oncotarget
information resource reference: CD90low MSCs modulate intratumoral immunity to confer antitumor activity in a mouse model of ovarian cancer. Oncotarget. 2019 Jul 09; 10(43):4479-4491.
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linked information resource: Coxiella burnetii Epitope-Specific T-Cell Responses in Patients with Chronic Q Fever.

Coxiella burnetii Epitope-Specific T-Cell Responses in Patients with Chronic Q Fever.
PubMed Identifier: 31331958
author list: Scholzen A, Richard G, Moise L, Hartman E, Bleeker-Rovers CP, Reeves PM, Raju Paul S, Martin WD, De Groot AS, Poznansky MC, Sluder AE, Garritsen A
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information resource reference: Coxiella burnetii Epitope-Specific T-Cell Responses in Patients with Chronic Q Fever. Infect Immun. 2019 10; 87(10).
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Authorship 136540
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linked information resource: Thymocyte emigration is mediated by active movement away from stroma-derived factors.

Raju Paul, Susan
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Persis, Cyrus and Marlow B. Harrison Professor of Medicine
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linked information resource: Multiple clinically relevant immunotherapies prolong the function of microencapsulated porcine islet xenografts in diabetic NOD mice without the use of anti-CD154 mAb.

Multiple clinically relevant immunotherapies prolong the function of microencapsulated porcine islet xenografts in diabetic NOD mice without the use of anti-CD154 mAb.
PubMed Identifier: 31903659
author list: Safley SA, Barber GF, Holdcraft RW, Gazda LS, Duncanson S, Poznansky MC, Sambanis A, Weber CJ
published in: Xenotransplantation
information resource reference: Multiple clinically relevant immunotherapies prolong the function of microencapsulated porcine islet xenografts in diabetic NOD mice without the use of anti-CD154 mAb. Xenotransplantation. 2020 07; 27(4):e12577.
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linked information resource: A cellular abnormality in glucocorticoid resistant asthma.

Authorship 178553
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linked information resource: Isolation and transduction of CD34+ cells from small quantities of peripheral blood from HIV-1-infected patients not treated with hemopoietic growth factors.

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linked information resource: Rethinking the role of hydroxychloroquine in the treatment of COVID-19.

Rethinking the role of hydroxychloroquine in the treatment of COVID-19.
PubMed Identifier: 32350928
author list: Meyerowitz EA, Vannier AGL, Friesen MGN, Schoenfeld S, Gelfand JA, Callahan MV, Kim AY, Reeves PM, Poznansky MC
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information resource reference: Rethinking the role of hydroxychloroquine in the treatment of COVID-19. FASEB J. 2020 05; 34(5):6027-6037.
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Genomic Instability in Multiple Myeloma.
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linked information resource: Genomic Instability in Multiple Myeloma.

Authorship 1254532
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linked information resource: CXCR4 antagonist AMD3100 (plerixafor): From an impurity to a therapeutic agent.

CXCR4 antagonist AMD3100 (plerixafor): From an impurity to a therapeutic agent.
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author list: Wang J, Tannous BA, Poznansky MC, Chen H
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information resource reference: CXCR4 antagonist AMD3100 (plerixafor): From an impurity to a therapeutic agent. Pharmacol Res. 2020 09; 159:105010.
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linked information resource: Murine B16 melanomas expressing high levels of the chemokine stromal-derived factor-1/CXCL12 induce tumor-specific T cell chemorepulsion and escape from immune control.

Authorship 1275785
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linked information resource: Novel multiparameter correlates of Coxiella burnetii infection and vaccination identified by longitudinal deep immune profiling.

Novel multiparameter correlates of Coxiella burnetii infection and vaccination identified by longitudinal deep immune profiling.
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linked information resource: Clinical sensitivity and interpretation of PCR and serological COVID-19 diagnostics for patients presenting to the hospital.

Clinical sensitivity and interpretation of PCR and serological COVID-19 diagnostics for patients presenting to the hospital.
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author list: Miller TE, Garcia Beltran WF, Bard AZ, Gogakos T, Anahtar MN, Astudillo MG, Yang D, Thierauf J, Fisch AS, Mahowald GK, Fitzpatrick MJ, Nardi V, Feldman J, Hauser BM, Caradonna TM, Marble HD, Ritterhouse LL, Turbett SE, Batten J, Georgantas NZ, Alter G, Schmidt AG, Harris JB, Gelfand JA, Poznansky MC, Bernstein BE, Louis DN, Dighe A, Charles RC, Ryan ET, Branda JA, Pierce VM, Murali MR, Iafrate AJ, Rosenberg ES, Lennerz JK
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High Seroprevalence of Anti-SARS-CoV-2 Antibodies in Chelsea, Massachusetts.
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linked information resource: Multiple SARS-CoV-2 variants escape neutralization by vaccine-induced humoral immunity.

Multiple SARS-CoV-2 variants escape neutralization by vaccine-induced humoral immunity.
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linked information resource: Polyfunctionality of the CXCR4/CXCL12 axis in health and disease: Implications for therapeutic interventions in cancer and immune-mediated diseases.

Polyfunctionality of the CXCR4/CXCL12 axis in health and disease: Implications for therapeutic interventions in cancer and immune-mediated diseases.
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linked information resource: Multiple SARS-CoV-2 variants escape neutralization by vaccine-induced humoral immunity.

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linked information resource: Deep immune profiling of whole blood to identify early immune signatures that correlate to patient outcome after major trauma.

Multiple SARS-CoV-2 variants escape neutralization by vaccine-induced humoral immunity.
PubMed Identifier: 33743213
author list: Garcia-Beltran WF, Lam EC, St Denis K, Nitido AD, Garcia ZH, Hauser BM, Feldman J, Pavlovic MN, Gregory DJ, Poznansky MC, Sigal A, Schmidt AG, Iafrate AJ, Naranbhai V, Balazs AB
published in: Cell
information resource reference: Multiple SARS-CoV-2 variants escape neutralization by vaccine-induced humoral immunity. Cell. 2021 04 29; 184(9):2372-2383.e9.
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Deep immune profiling of whole blood to identify early immune signatures that correlate to patient outcome after major trauma.
PubMed Identifier: 33755643
author list: Mendoza AE, Raju Paul S, El Hechi M, Naar L, Nederpelt C, Mikdad S, van Erp I, Hess JM, Velmahos GC, Poznansky M, Reeves P
published in: The journal of trauma and acute care surgery
information resource reference: Deep immune profiling of whole blood to identify early immune signatures that correlate to patient outcome after major trauma. J Trauma Acute Care Surg. 2021 06 01; 90(6):959-966.
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linked information resource: Multiple SARS-CoV-2 variants escape neutralization by vaccine-induced humoral immunity.

Multiple SARS-CoV-2 variants escape neutralization by vaccine-induced humoral immunity.
PubMed Identifier: 33930298
author list: Garcia-Beltran WF, Lam EC, St Denis K, Nitido AD, Garcia ZH, Hauser BM, Feldman J, Pavlovic MN, Gregory DJ, Poznansky MC, Sigal A, Schmidt AG, Iafrate AJ, Naranbhai V, Balazs AB
published in: Cell
information resource reference: Multiple SARS-CoV-2 variants escape neutralization by vaccine-induced humoral immunity. Cell. 2021 Apr 29; 184(9):2523.
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Authorship 1371244
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linked information resource: The 2021 FASEB virtual Catalyst Conference on B Cells in Injury and Regeneration, April 21, 2021.

The 2021 FASEB virtual Catalyst Conference on B Cells in Injury and Regeneration, April 21, 2021.
PubMed Identifier: 34224602
author list: Kawai K, Stowe AM, Evans CL, Sîrbulescu RF, Hanidziar D, Lee KM, Tedder TF, Poznansky MC
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linked information resource: Whole Blood Interferon ? Release Is a More Sensitive Marker of Prior Exposure to Coxiella burnetii Than Are Antibody Responses.

Whole Blood Interferon ? Release Is a More Sensitive Marker of Prior Exposure to Coxiella burnetii Than Are Antibody Responses.
PubMed Identifier: 34394097
author list: Scholzen A, de Vries M, Duerr HP, Roest HJ, Sluder AE, Poznansky MC, Kouwijzer MLCE, Garritsen A
published in: Frontiers in immunology
information resource reference: Whole Blood Interferon ? Release Is a More Sensitive Marker of Prior Exposure to Coxiella burnetii Than Are Antibody Responses. Front Immunol. 2021; 12:701811.
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linked information resource: Fresh Tissue Multi-omics Profiling Reveals Immune Classification and Suggests Immunotherapy Candidates for Conventional Chondrosarcoma.

Fresh Tissue Multi-omics Profiling Reveals Immune Classification and Suggests Immunotherapy Candidates for Conventional Chondrosarcoma.
PubMed Identifier: 34426437
author list: Li B, Li G, Yan X, Zhu D, Lin PP, Wang Z, Qu H, He X, Fu Y, Zhu X, Lin P, Zhang J, Li X, Dai H, Chen H, Poznansky MC, Lin N, Ye Z
published in: Clinical cancer research : an official journal of the American Association for Cancer Research
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Comparative immunogenicity and effectiveness of mRNA-1273, BNT162b2 and Ad26.COV2.S COVID-19 vaccines.
PubMed Identifier: 34671780
author list: Naranbhai V, Garcia-Beltran WF, Chang CC, Mairena CB, Thierauf JC, Kirkpatrick G, Onozato ML, Cheng J, St Denis KJ, Lam EC, Kaseke C, Tano-Menka R, Yang D, Pavlovic M, Yang W, Kui A, Miller TE, Astudillo MG, Cahill JE, Dighe AS, Gregory DJ, Poznansky MC, Gaiha GD, Balazs AB, Iafrate AJ
published in: medRxiv : the preprint server for health sciences
information resource reference: Comparative immunogenicity and effectiveness of mRNA-1273, BNT162b2 and Ad26.COV2.S COVID-19 vaccines. medRxiv. 2021 Oct 13.
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Authorship 223181
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linked information resource: Methods for quantitation of leukocyte chemotaxis and fugetaxis.

Authorship 1410938
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linked author: Poznansky, Mark
linked information resource: B cells support the repair of injured tissues by adopting MyD88-dependent regulatory functions and phenotype.

Authorship 1413501
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linked information resource: Mathematical Modeling to Simulate the Effect of Adding Radiation Therapy to Immunotherapy and Application to Hepatocellular Carcinoma.

B cells support the repair of injured tissues by adopting MyD88-dependent regulatory functions and phenotype.
PubMed Identifier: 34792819
author list: Sîrbulescu RF, Mamidi A, Chan SC, Jin G, Boukhali M, Sobell D, Ilies I, Chung JY, Haas W, Whalen MJ, Sluder AE, Poznansky MC
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information resource reference: B cells support the repair of injured tissues by adopting MyD88-dependent regulatory functions and phenotype. FASEB J. 2021 12; 35(12):e22019.
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Mathematical Modeling to Simulate the Effect of Adding Radiation Therapy to Immunotherapy and Application to Hepatocellular Carcinoma.
PubMed Identifier: 34774999
author list: Sung W, Hong TS, Poznansky MC, Paganetti H, Grassberger C
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information resource reference: Mathematical Modeling to Simulate the Effect of Adding Radiation Therapy to Immunotherapy and Application to Hepatocellular Carcinoma. Int J Radiat Oncol Biol Phys. 2022 03 15; 112(4):1055-1062.
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Authorship 1417398
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linked information resource: Comparative Immunogenicity and Effectiveness of mRNA-1273, BNT162b2, and Ad26.COV2.S COVID-19 Vaccines.

Comparative Immunogenicity and Effectiveness of mRNA-1273, BNT162b2, and Ad26.COV2.S COVID-19 Vaccines.
PubMed Identifier: 34888672
author list: Naranbhai V, Garcia-Beltran WF, Chang CC, Berrios Mairena C, Thierauf JC, Kirkpatrick G, Onozato ML, Cheng J, St Denis KJ, Lam EC, Kaseke C, Tano-Menka R, Yang D, Pavlovic M, Yang W, Kui A, Miller TE, Astudillo MG, Cahill JE, Dighe AS, Gregory DJ, Poznansky MC, Gaiha GD, Balazs AB, Iafrate AJ
published in: The Journal of infectious diseases
information resource reference: Comparative Immunogenicity and Effectiveness of mRNA-1273, BNT162b2, and Ad26.COV2.S COVID-19 Vaccines. J Infect Dis. 2022 04 01; 225(7):1141-1150.
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Authorship 1419598
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linked information resource: mRNA-based COVID-19 vaccine boosters induce neutralizing immunity against SARS-CoV-2 Omicron variant.

Authorship 1419273
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linked author: Poznansky, Mark
linked information resource: 209.6: Long-term Functional Survival of Human Stem Cell-derived Islets Microencapsulated in Alginate With CXCL12 in Non-human Primates Without Immunosuppression.

mRNA-based COVID-19 vaccine boosters induce neutralizing immunity against SARS-CoV-2 Omicron variant.
PubMed Identifier: 34931201
author list: Garcia-Beltran WF, St Denis KJ, Hoelzemer A, Lam EC, Nitido AD, Sheehan ML, Berrios C, Ofoman O, Chang CC, Hauser BM, Feldman J, Gregory DJ, Poznansky MC, Schmidt AG, Iafrate AJ, Naranbhai V, Balazs AB
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information resource reference: mRNA-based COVID-19 vaccine boosters induce neutralizing immunity against SARS-CoV-2 Omicron variant. medRxiv. 2021 Dec 14.
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209.6: Long-term Functional Survival of Human Stem Cell-derived Islets Microencapsulated in Alginate With CXCL12 in Non-human Primates Without Immunosuppression.
PubMed Identifier: 34908317
author list: Alagpulinsa DA, Jei L, Pop R, Veres A, Deng H, Zhang J, Kawai K, Collins SS, Sobell D, Chapin MH, Verill D, Melton DA, Markmann JF, Poznansky MC
published in: Transplantation
information resource reference: 209.6: Long-term Functional Survival of Human Stem Cell-derived Islets Microencapsulated in Alginate With CXCL12 in Non-human Primates Without Immunosuppression. Transplantation. 2021 Dec 01; 105(12 Suppl 2):S16.
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Authorship 1422202
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linked information resource: mRNA-based COVID-19 vaccine boosters induce neutralizing immunity against SARS-CoV-2 Omicron variant.

mRNA-based COVID-19 vaccine boosters induce neutralizing immunity against SARS-CoV-2 Omicron variant.
PubMed Identifier: 34995482
author list: Garcia-Beltran WF, St Denis KJ, Hoelzemer A, Lam EC, Nitido AD, Sheehan ML, Berrios C, Ofoman O, Chang CC, Hauser BM, Feldman J, Roederer AL, Gregory DJ, Poznansky MC, Schmidt AG, Iafrate AJ, Naranbhai V, Balazs AB
published in: Cell
information resource reference: mRNA-based COVID-19 vaccine boosters induce neutralizing immunity against SARS-CoV-2 Omicron variant. Cell. 2022 02 03; 185(3):457-466.e4.
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Q fever vaccine development: Challenges and progress in balancing safety and efficacy.
PubMed Identifier: 35028619
author list: Sluder AE, Poznansky MC
published in: Cell reports. Medicine
information resource reference: Q fever vaccine development: Challenges and progress in balancing safety and efficacy. Cell Rep Med. 2021 12 21; 2(12):100480.
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Authorship 1426984
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linked information resource: Q fever vaccine development: Challenges and progress in balancing safety and efficacy.

Authorship 203501
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linked author: Poznansky, Mark
linked information resource: Experience of HIV disease in a London District General Hospital.

Authorship 225478
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linked information resource: Dynamic alterations in chemokine gradients induce transendothelial shuttling of human T cells under physiologic shear conditions.

Authorship 1435234
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linked author: Poznansky, Mark
linked information resource: Differential Severe Acute Respiratory Syndrome Coronavirus 2 Antibody Profiles After Allergic Reactions to Messenger RNA Coronavirus Disease 2019 Vaccine.

Differential Severe Acute Respiratory Syndrome Coronavirus 2 Antibody Profiles After Allergic Reactions to Messenger RNA Coronavirus Disease 2019 Vaccine.
PubMed Identifier: 35325158
author list: Maron JS, Conroy M, Naranbai V, Samarakoon U, Motazedi T, Farmer JR, Freeman E, Banerji A, Bartsch YC, Gregory DJ, Poznansky MC, Alter G, Blumenthal KG
published in: The Journal of infectious diseases
information resource reference: Differential Severe Acute Respiratory Syndrome Coronavirus 2 Antibody Profiles After Allergic Reactions to Messenger RNA Coronavirus Disease 2019 Vaccine. J Infect Dis. 2022 09 28; 226(7):1231-1236.
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Authorship 286796
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linked author: Poznansky, Mark
linked information resource: Accelerated vaccine development against emerging infectious diseases.

Authorship 1445679
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author rank in publication: 19
linked author: Poznansky, Mark
linked information resource: Response to Severe Acute Respiratory Syndrome Coronavirus 2 Initial Series and Additional Dose Vaccine in Patients With Predominant Antibody Deficiency.

Response to Severe Acute Respiratory Syndrome Coronavirus 2 Initial Series and Additional Dose Vaccine in Patients With Predominant Antibody Deficiency.
PubMed Identifier: 35381395
author list: Barmettler S, DiGiacomo DV, Yang NJ, Lam T, Naranbhai V, Dighe AS, Burke KE, Blumenthal KG, Ling M, Hesterberg PE, Saff RR, MacLean J, Ofoman O, Berrios C, St Denis KJ, Lam EC, Gregory D, Iafrate AJ, Poznansky M, Lee H, Balazs A, Pillai S, Farmer JR
published in: The journal of allergy and clinical immunology. In practice
information resource reference: Response to Severe Acute Respiratory Syndrome Coronavirus 2 Initial Series and Additional Dose Vaccine in Patients With Predominant Antibody Deficiency. J Allergy Clin Immunol Pract. 2022 06; 10(6):1622-1634.e4.
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Authorship 1451838
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linked information resource: Repertoires of SARS-CoV-2 epitopes targeted by antibodies vary according to severity of COVID-19.

Repertoires of SARS-CoV-2 epitopes targeted by antibodies vary according to severity of COVID-19.
PubMed Identifier: 35587156
author list: Gregory DJ, Vannier A, Duey AH, Roady TJ, Dzeng RK, Pavlovic MN, Chapin MH, Mukherjee S, Wilmot H, Chronos N, Charles RC, Ryan ET, LaRocque RC, Miller TE, Garcia-Beltran WF, Thierauf JC, Iafrate AJ, Mullenbrock S, Stump MD, Wetzel RK, Polakiewicz RD, Naranbhai V, Poznansky MC
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information resource reference: Repertoires of SARS-CoV-2 epitopes targeted by antibodies vary according to severity of COVID-19. Virulence. 2022 12; 13(1):890-902.
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Authorship 1466151
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linked information resource: Natural Exposure- and Vaccination-Induced Profiles of Ex Vivo Whole Blood Cytokine Responses to Coxiella burnetii.

Authorship 1460571
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linked information resource: Evaluation of a Human T Cell-Targeted Multi-Epitope Vaccine for Q Fever in Animal Models of Coxiella burnetii Immunity.

Authorship 1459451
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linked author: Poznansky, Mark
linked information resource: The 2022 FASEB virtual Catalyst Conference on B Cells in Injury and Regeneration, March 30, 2022.

Natural Exposure- and Vaccination-Induced Profiles of Ex Vivo Whole Blood Cytokine Responses to Coxiella burnetii.
PubMed Identifier: 35812430
author list: Raju Paul S, Scholzen A, Mukhtar G, Wilkinson S, Hobson P, Dzeng RK, Evans J, Robson J, Cobbold R, Graves S, Poznansky MC, Garritsen A, Sluder AE
published in: Frontiers in immunology
information resource reference: Natural Exposure- and Vaccination-Induced Profiles of Ex Vivo Whole Blood Cytokine Responses to Coxiella burnetii. Front Immunol. 2022; 13:886698.
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The 2022 FASEB virtual Catalyst Conference on B Cells in Injury and Regeneration, March 30, 2022.
PubMed Identifier: 35857314
author list: Dwyer LJ, Stowe AM, Doyle K, Popovich P, Engler-Chiurazzi E, LeGuern C, Buckwalter MS, Poznansky MC, Sîrbulescu RF
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information resource reference: The 2022 FASEB virtual Catalyst Conference on B Cells in Injury and Regeneration, March 30, 2022. FASEB J. 2022 08; 36(8):e22459.
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Evaluation of a Human T Cell-Targeted Multi-Epitope Vaccine for Q Fever in Animal Models of Coxiella burnetii Immunity.
PubMed Identifier: 35651616
author list: Sluder AE, Raju Paul S, Moise L, Dold C, Richard G, Silva-Reyes L, Baeten LA, Scholzen A, Reeves PM, Pollard AJ, Garritsen A, Bowen RA, De Groot AS, Rollier C, Poznansky MC
published in: Frontiers in immunology
information resource reference: Evaluation of a Human T Cell-Targeted Multi-Epitope Vaccine for Q Fever in Animal Models of Coxiella burnetii Immunity. Front Immunol. 2022; 13:901372.
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Authorship 1476899
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linked author: Poznansky, Mark
linked information resource: Precise reconstruction of the TME using bulk RNA-seq and a machine learning algorithm trained on artificial transcriptomes.

Precise reconstruction of the TME using bulk RNA-seq and a machine learning algorithm trained on artificial transcriptomes.
PubMed Identifier: 35944503
author list: Zaitsev A, Chelushkin M, Dyikanov D, Cheremushkin I, Shpak B, Nomie K, Zyrin V, Nuzhdina E, Lozinsky Y, Zotova A, Degryse S, Kotlov N, Baisangurov A, Shatsky V, Afenteva D, Kuznetsov A, Paul SR, Davies DL, Reeves PM, Lanuti M, Goldberg MF, Tazearslan C, Chasse M, Wang I, Abdou M, Aslanian SM, Andrewes S, Hsieh JJ, Ramachandran A, Lyu Y, Galkin I, Svekolkin V, Cerchietti L, Poznansky MC, Ataullakhanov R, Fowler N, Bagaev A
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information resource reference: Precise reconstruction of the TME using bulk RNA-seq and a machine learning algorithm trained on artificial transcriptomes. Cancer Cell. 2022 08 08; 40(8):879-894.e16.
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Optimized ACE2 decoys neutralize antibody-resistant SARS-CoV-2 variants through functional receptor mimicry and treat infection in vivo.
PubMed Identifier: 36475798
author list: Torchia JA, Tavares AH, Carstensen LS, Chen DY, Huang J, Xiao T, Mukherjee S, Reeves PM, Tu H, Sluder AE, Chen B, Kotton DN, Bowen RA, Saeed M, Poznansky MC, Freeman GJ
published in: Science advances
information resource reference: Optimized ACE2 decoys neutralize antibody-resistant SARS-CoV-2 variants through functional receptor mimicry and treat infection in vivo. Sci Adv. 2022 12 09; 8(49):eabq6527.
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Authorship 1509442
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linked information resource: Optimized ACE2 decoys neutralize antibody-resistant SARS-CoV-2 variants through functional receptor mimicry and treat infection in vivo.

B cell treatment promotes a neuroprotective microenvironment after traumatic brain injury through reciprocal immunomodulation with infiltrating peripheral myeloid cells.
PubMed Identifier: 37259118
author list: Dwyer LJ, Maheshwari S, Levy E, Poznansky MC, Whalen MJ, Sîrbulescu RF
published in: Journal of neuroinflammation
information resource reference: B cell treatment promotes a neuroprotective microenvironment after traumatic brain injury through reciprocal immunomodulation with infiltrating peripheral myeloid cells. J Neuroinflammation. 2023 May 31; 20(1):133.
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B cell-dependent subtypes and treatment-based immune correlates to survival in stage 3 and 4 lung adenocarcinomas.
PubMed Identifier: 37020749
author list: Raju Paul S, Valiev I, Korek SE, Zyrin V, Shamsutdinova D, Gancharova O, Zaitsev A, Nuzhdina E, Davies DL, Dagogo-Jack I, Frenkel F, Brown JH, Hess JM, Viet S, Petersen JL, Wright CD, Ott HC, Auchincloss HG, Muniappan A, Shioda T, Lanuti M, Davis CM, Ehli EA, Hung YP, Mino-Kenudson M, Tsiper M, Sluder AE, Reeves PM, Kotlov N, Bagaev A, Ataullakhanov R, Poznansky MC
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information resource reference: B cell-dependent subtypes and treatment-based immune correlates to survival in stage 3 and 4 lung adenocarcinomas. FASEB Bioadv. 2023 Apr; 5(4):156-170.
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Ragon Institute of MGH, MIT and Harvard
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Authorship 1559117
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linked information resource: B cell-dependent subtypes and treatment-based immune correlates to survival in stage 3 and 4 lung adenocarcinomas.

Authorship 1568516
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linked information resource: B cell treatment promotes a neuroprotective microenvironment after traumatic brain injury through reciprocal immunomodulation with infiltrating peripheral myeloid cells.

Authorship 1552295
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linked information resource: Combinatorial islet protective therapeutic approaches in ß-cell transplantation: Rationally designed solutions using a target product profile.

Combinatorial islet protective therapeutic approaches in ß-cell transplantation: Rationally designed solutions using a target product profile.
PubMed Identifier: 37415930
author list: Lu K, Brauns T, Sluder AE, Poznansky MC, Dogan F
published in: FASEB bioAdvances
information resource reference: Combinatorial islet protective therapeutic approaches in ß-cell transplantation: Rationally designed solutions using a target product profile. FASEB Bioadv. 2023 Jul; 5(7):287-304.
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linked information resource: https://connects.catalyst.harvard.edu/Profiles/profile/220735338

https://connects.catalyst.harvard.edu/Profiles/profile/220735338
PubMed Identifier: 37712342
author list: Sremac M, Luo H, Deng H, Parr MFE, Hutcheson J, Verde PS, Alagpulinsa DA, Kitzmann JM, Papas KK, Brauns T, Markmann JF, Lei J, Poznansky MC
published in: Xenotransplantation
information resource reference: Short-term function and immune-protection of microencapsulated adult porcine islets with alginate incorporating CXCL12 in healthy and diabetic non-human primates without systemic immune suppression: A pilot study. Xenotransplantation. 2023 Nov-Dec; 30(6):e12826.
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label: Short-term function and immune-protection of microencapsulated adult porcine islets with alginate incorporating CXCL12 in healthy and diabetic non-human primates without systemic immune suppression: A pilot study.

Research Fellow in Medicine
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Authorship 1601001
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linked author: Poznansky, Mark
linked information resource: Cytometry profiling of ex vivo recall responses to Coxiella burnetii in previously naturally exposed individuals reveals long-term changes in both adaptive and innate immune cellular compartments.

Cytometry profiling of ex vivo recall responses to Coxiella burnetii in previously naturally exposed individuals reveals long-term changes in both adaptive and innate immune cellular compartments.
PubMed Identifier: 37885896
author list: Raju Paul S, Scholzen A, Reeves PM, Shepard R, Hess JM, Dzeng RK, Korek S, Garritsen A, Poznansky MC, Sluder AE
published in: Frontiers in immunology
information resource reference: Cytometry profiling of ex vivo recall responses to Coxiella burnetii in previously naturally exposed individuals reveals long-term changes in both adaptive and innate immune cellular compartments. Front Immunol. 2023; 14:1249581.
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Authorship 1623770
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author rank in publication: 5
linked author: Poznansky, Mark
linked information resource: Intruders or protectors - the multifaceted role of B cells in CNS disorders.

Intruders or protectors - the multifaceted role of B cells in CNS disorders.
PubMed Identifier: 38269112
author list: Aspden JW, Murphy MA, Kashlan RD, Xiong Y, Poznansky MC, Sîrbulescu RF
published in: Frontiers in cellular neuroscience
information resource reference: Intruders or protectors - the multifaceted role of B cells in CNS disorders. Front Cell Neurosci. 2023; 17:1329823.
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Authorship 181206
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linked author: Poznansky, Mark
linked information resource: Transendothelial movement of liposomes in vitro mediated by cancer cells, neutrophils or histamine.

Authorship 1638660
type: Authorship
author rank in publication: 11
linked author: Poznansky, Mark
linked information resource: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccine response in adults with predominantly antibody deficiency.

Authorship 1635754
type: Authorship
author rank in publication: 22
linked author: Poznansky, Mark
linked information resource: Comparative immunogenicity and effectiveness of mRNA-1273, BNT162b2 and Ad26.COV2.S COVID-19 vaccines.

Authorship 1639446
type: Authorship
author rank in publication: 8
linked author: Poznansky, Mark
linked information resource: Ongoing evolution of SARS-CoV-2 drives escape from mRNA vaccine-induced humoral immunity.

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccine response in adults with predominantly antibody deficiency.
PubMed Identifier: 38544577
author list: Zhang AM, Elmoursi A, DiGiacomo DV, Zhou B, Tandon M, Hong JS, Yang NJ, Ong MS, Dighe AS, Berrios C, Poznansky MC, Iafrate AJ, Naranbhai V, Balazs A, Pillai S, Farmer JR, Barmettler S
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Ongoing evolution of SARS-CoV-2 drives escape from mRNA vaccine-induced humoral immunity.
PubMed Identifier: 38496628
author list: Roederer AL, Cao Y, Denis KS, Sheehan ML, Li CJ, Lam EC, Gregory DJ, Poznansky MC, Iafrate AJ, Canaday DH, Gravenstein S, Garcia-Beltran WF, Balazs AB
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Assistant Professor of Surgery
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position in department: Surgery
position in division: https://connects.catalyst.harvard.edu/Profiles/profile/1229413
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HR job title: Assistant Professor of Surgery
position in organization: Massachusetts General Hospital

Authorship 1655187
type: Authorship
author rank in publication: 4
linked author: Poznansky, Mark
linked information resource: Immunomodulatory drugs: a promising clinical ally for cancer immunotherapy.

Immunomodulatory drugs: a promising clinical ally for cancer immunotherapy.
PubMed Identifier: 38821771
author list: Colley A, Brauns T, Sluder AE, Poznansky MC, Gemechu Y
published in: Trends in molecular medicine
information resource reference: Immunomodulatory drugs: a promising clinical ally for cancer immunotherapy. Trends Mol Med. 2024 08; 30(8):765-780.
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Authorship 1662530
type: Authorship
author rank in publication: 4
linked author: Poznansky, Mark
linked information resource: Targeting metabolic pathways to counter cancer immunotherapy resistance.

Targeting metabolic pathways to counter cancer immunotherapy resistance.
PubMed Identifier: 38876831
author list: Agarwala Y, Brauns TA, Sluder AE, Poznansky MC, Gemechu Y
published in: Trends in immunology
information resource reference: Targeting metabolic pathways to counter cancer immunotherapy resistance. Trends Immunol. 2024 07; 45(7):486-494.
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publication date: 2024-06-13T00:00:00
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Claude E. Welch Professor of Surgery, Emeritus
is primary position: true
position in department: Emeritus
position in division: https://connects.catalyst.harvard.edu/Profiles/profile/1229413
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HR job title: Claude E. Welch Professor of Surgery, Emeritus
position in organization: Harvard Medical School

Authorship 1664144
type: Authorship
author rank in publication: 26
linked author: Poznansky, Mark
linked information resource: Allogeneic B cell immunomodulatory therapy in amyotrophic lateral sclerosis.

Allogeneic B cell immunomodulatory therapy in amyotrophic lateral sclerosis.
PubMed Identifier: 38967302
author list: Sîrbulescu RF, Nicholson K, Kawai K, Hilton OM, Sobell D, Jin G, Verrill DE, Dwyer LJ, Xiong Y, Bachanová P, Kim SE, Gallup S, Gelevski D, Daley H, Hernandez Rodriguez DE, Negre H, Sturtevant O, Nikiforow S, Ritz J, Chen YB, Reeves PM, Sluder AE, Berry JD, Sadri-Vakili G, Cudkowicz M, Poznansky MC
published in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology
information resource reference: Allogeneic B cell immunomodulatory therapy in amyotrophic lateral sclerosis. FASEB J. 2024 Jul 15; 38(13):e23796.
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publication date: 2024-07-15T00:00:00
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Assistant Professor of Radiology
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HR job title: Assistant Professor of Radiology
position in organization: Massachusetts General Hospital

Assistant Professor of Neurology
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position in department: Neurology
position in division: https://connects.catalyst.harvard.edu/Profiles/profile/1229413
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HR job title: Assistant Professor of Neurology
position in organization: Massachusetts General Hospital

William Bosworth Castle Professor of Medicine
is primary position: true
position in department: Medicine
position in division: Vaccine Research
sort order: 1
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HR job title: William Bosworth Castle Professor of Medicine
position in organization: Beth Israel Deaconess Medical Center

Associate Professor of Medicine
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position in department: Medicine
position in division: Infectious Disease
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HR job title: Associate Professor of Medicine
position in organization: Massachusetts General Hospital

Professor of Medicine, Part-time
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position in department: Medicine
position in division: Infectious Disease
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HR job title: Professor of Medicine, Part-time
position in organization: Massachusetts General Hospital

Professor of Microbiology
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position in division: https://connects.catalyst.harvard.edu/Profiles/profile/1229413
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HR job title: Professor of Microbiology
position in organization: Dana-Farber Cancer Institute

Associate Professor of Medicine
is primary position: true
position in department: Medicine
position in division: MGH Cancer Center Research
sort order: 1
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HR job title: Associate Professor of Medicine
position in organization: Massachusetts General Hospital

Authorship 244494
type: Authorship
author rank in publication: 2
linked author: Poznansky, Mark
linked information resource: Changing patterns of presentations of patients with HIV-related disease at a tertiary referral centre and its implications for physician training.

Assistant Professor of Medicine
is primary position: true
position in department: Medicine
position in division: Ragon Institute of MGH, MIT and Harvard
sort order: 1
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HR job title: Assistant Professor of Medicine
position in organization: Massachusetts General Hospital

Authorship 1688744
type: Authorship
author rank in publication: 29
linked author: Poznansky, Mark
linked information resource: Harnessing cellular therapeutics for type 1 diabetes mellitus: progress, challenges, and the road ahead.

Harnessing cellular therapeutics for type 1 diabetes mellitus: progress, challenges, and the road ahead.
PubMed Identifier: 39227741
author list: Grattoni A, Korbutt G, Tomei AA, García AJ, Pepper AR, Stabler C, Brehm M, Papas K, Citro A, Shirwan H, Millman JR, Melero-Martin J, Graham M, Sefton M, Ma M, Kenyon N, Veiseh O, Desai TA, Nostro MC, Marinac M, Sykes M, Russ HA, Odorico J, Tang Q, Ricordi C, Latres E, Mamrak NE, Giraldo J, Poznansky MC, de Vos P
published in: Nature reviews. Endocrinology
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Authorship 1695853
type: Authorship
author rank in publication: 5
linked author: Poznansky, Mark
linked information resource: Resistance is reality: findings from the first Ukrainian cumulative antibiogram.

Authorship 1699627
type: Authorship
author rank in publication: 3
linked author: Poznansky, Mark
linked information resource: A HABA dye-based colorimetric assay to detect unoccupied biotin binding sites in an avidin-containing fusion protein.

A HABA dye-based colorimetric assay to detect unoccupied biotin binding sites in an avidin-containing fusion protein.
PubMed Identifier: 39268899
author list: Mukherjee S, Leblanc P, Poznansky MC, Sluder AE
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information resource reference: A HABA dye-based colorimetric assay to detect unoccupied biotin binding sites in an avidin-containing fusion protein. Biotechniques. 2024 Oct; 76(10):485-494.
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Resistance is reality: findings from the first Ukrainian cumulative antibiogram.
PubMed Identifier: 39386375
author list: Vodianyk A, Holovnia O, Diomin E, Letourneau AR, Poznansky MC, Shenoy ES, Turbett SE
published in: JAC-antimicrobial resistance
information resource reference: Resistance is reality: findings from the first Ukrainian cumulative antibiogram. JAC Antimicrob Resist. 2024 Oct; 6(5):dlae156.
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Authorship 86538
type: Authorship
author rank in publication: 2
linked author: Poznansky, Mark
linked information resource: Physicians' experience and survival in patients with AIDS.

Ongoing evolution of SARS-CoV-2 drives escape from mRNA vaccine-induced humoral immunity.
PubMed Identifier: 39657661
author list: Roederer AL, Cao Y, St Denis K, Sheehan ML, Li CJ, Lam EC, Gregory DJ, Poznansky MC, Iafrate AJ, Canaday DH, Gravenstein S, Garcia-Beltran WF, Balazs AB
published in: Cell reports. Medicine
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publication date: 2024-12-09T00:00:00
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type: Article
type: Document
type: Information Resource

Intratumoral immune cell manipulations as a strategy to enhance cancer vaccine efficiency.
PubMed Identifier: 39672756
author list: Adeosun J, Shaikh MOF, Brauns T, Agarwala Y, Poznansky MC, Gemechu Y
published in: Trends in cancer
information resource reference: Intratumoral immune cell manipulations as a strategy to enhance cancer vaccine efficiency. Trends Cancer. 2025 Mar; 11(3):192-195.
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publication date: 2024-12-12T00:00:00
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Authorship 1719851
type: Authorship
author rank in publication: 5
linked author: Poznansky, Mark
linked information resource: Intratumoral immune cell manipulations as a strategy to enhance cancer vaccine efficiency.

Authorship 1715509
type: Authorship
author rank in publication: 8
linked author: Poznansky, Mark
linked information resource: Ongoing evolution of SARS-CoV-2 drives escape from mRNA vaccine-induced humoral immunity.

Authorship 699206
type: Authorship
author rank in publication: 22
linked author: Poznansky, Mark
linked information resource: Near-infrared laser adjuvant for influenza vaccine.

Near-infrared laser adjuvant for influenza vaccine.
PubMed Identifier: 24349390
author list: Kashiwagi S, Yuan J, Forbes B, Hibert ML, Lee EL, Whicher L, Goudie C, Yang Y, Chen T, Edelblute B, Collette B, Edington L, Trussler J, Nezivar J, Leblanc P, Bronson R, Tsukada K, Suematsu M, Dover J, Brauns T, Gelfand J, Poznansky MC
published in: PloS one
information resource reference: Near-infrared laser adjuvant for influenza vaccine. PLoS One. 2013; 8(12):e82899.
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publication date: 2013-12-11T00:00:00
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Authorship 61131
type: Authorship
author rank in publication: 1
linked author: Poznansky, Mark
linked information resource: A rapid method for quantitating the frequency of peripheral blood cells containing HIV-1 DNA.

A novel mycobacterial Hsp70-containing fusion protein targeting mesothelin augments antitumor immunity and prolongs survival in murine models of ovarian cancer and mesothelioma.
PubMed Identifier: 24565018
author list: Yuan J, Kashiwagi S, Reeves P, Nezivar J, Yang Y, Arrifin NH, Nguyen M, Jean-Mary G, Tong X, Uppal P, Korochkina S, Forbes B, Chen T, Righi E, Bronson R, Chen H, Orsulic S, Brauns T, Leblanc P, Scholler N, Dranoff G, Gelfand J, Poznansky MC
published in: Journal of hematology & oncology
information resource reference: A novel mycobacterial Hsp70-containing fusion protein targeting mesothelin augments antitumor immunity and prolongs survival in murine models of ovarian cancer and mesothelioma. J Hematol Oncol. 2014 Feb 24; 7:15.
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publication date: 2014-02-24T00:00:00
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type: Academic Article
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type: Information Resource

Authorship 724844
type: Authorship
author rank in publication: 23
linked author: Poznansky, Mark
linked information resource: A novel mycobacterial Hsp70-containing fusion protein targeting mesothelin augments antitumor immunity and prolongs survival in murine models of ovarian cancer and mesothelioma.

Large Language Models in Infectious Diseases: A Systemic Review.
PubMed Identifier: 41756438
author list: Gorenshtein A, Klang E, Smith JJ, Dzeng R, Poznansky MC, Nadkarni GN, Omar M
published in: Research square
information resource reference: Large Language Models in Infectious Diseases: A Systemic Review. Res Sq. 2026 Feb 18.
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publication date: 2026-02-18T00:00:00
year: 2026
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 257790
type: Authorship
author rank in publication: 1
linked author: Poznansky, Mark
linked information resource: https://connects.catalyst.harvard.edu/Profiles/profile/1015368

Authorship 1783752
type: Authorship
author rank in publication: 5
linked author: Poznansky, Mark
linked information resource: Large Language Models in Infectious Diseases: A Systemic Review.

Authorship 1817575
type: Authorship
author rank in publication: 13
linked author: Poznansky, Mark
linked information resource: Pilot Study: Functional Survival of Human Stem Cell-Derived Islets Microencapsulated With Alginate Incorporating CXCL12 in Non-Human Primates Without Systemic Immunosuppression.

Authorship 1833909
type: Authorship
author rank in publication: 13
linked author: Poznansky, Mark
linked information resource: Impact of international observerships on Ukrainian healthcare professionals during the war: a cross-sectional survey study.

Authorship 1844959
type: Authorship
author rank in publication: 20
linked author: Poznansky, Mark
linked information resource: A Comparison of Tests for Detecting Prior Exposure to Coxiella burnetii for Use with Q-VAX in Australian Human Q Fever Vaccination.

Authorship 1845071
type: Authorship
author rank in publication: 9
linked author: Poznansky, Mark
linked information resource: Immune Composition and Immunotherapy Outcomes of Mesothelioma With BAP1, CDKN2A, MTAP, and NF2 Alterations.

A Comparison of Tests for Detecting Prior Exposure to Coxiella burnetii for Use with Q-VAX in Australian Human Q Fever Vaccination.
PubMed Identifier: 40573946
author list: Graves S, Robson J, Scholzen A, Dzeng R, Powell-Romero F, Evans J, Stenos J, Jeppesen M, Kouwijzer MLCE, Lankhof J, Raju Paul S, Proboste Ibertti T, Ball L, Powell H, Wilkinson S, van Schuppen E, Anker-Op den Brouw WJ, Cobbold R, Garritsen A, Poznansky MC, Sluder AE
published in: Vaccines
information resource reference: A Comparison of Tests for Detecting Prior Exposure to Coxiella burnetii for Use with Q-VAX in Australian Human Q Fever Vaccination. Vaccines (Basel). 2025 Jun 06; 13(6).
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publication date: 2025-06-06T00:00:00
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Pilot Study: Functional Survival of Human Stem Cell-Derived Islets Microencapsulated With Alginate Incorporating CXCL12 in Non-Human Primates Without Systemic Immunosuppression.
PubMed Identifier: 41431325
author list: Kawai K, Dogan F, Alagpulinsa DA, Pop R, Veres A, Sobell D, Deng H, Collins SH, Zhang J, Chapin MH, Markmann JF, Lei J, Poznansky MC
published in: Xenotransplantation
information resource reference: Pilot Study: Functional Survival of Human Stem Cell-Derived Islets Microencapsulated With Alginate Incorporating CXCL12 in Non-Human Primates Without Systemic Immunosuppression. Xenotransplantation. 2025 Nov-Dec; 32(6):e70098.
journal title abbreviation: Xenotransplantation
publication date: 2025-11-01T00:00:00
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type: Article
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Immune Composition and Immunotherapy Outcomes of Mesothelioma With BAP1, CDKN2A, MTAP, and NF2 Alterations.
PubMed Identifier: 40578509
author list: Dagogo-Jack I, Mitchell O, Codd E, Li A, Mitchell D, Flynn SE, Sivamanoharan N, Reeves P, Poznansky MC, Valiev I, Kosmin A, Yeap BY, Hambelton G, Iafrate AJ, Lennerz JK, Hung YP, Kindler H
published in: Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer
information resource reference: Immune Composition and Immunotherapy Outcomes of Mesothelioma With BAP1, CDKN2A, MTAP, and NF2 Alterations. J Thorac Oncol. 2025 Nov; 20(11):1615-1625.
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publication date: 2025-06-25T00:00:00
year: 2025
type: Academic Article
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Impact of international observerships on Ukrainian healthcare professionals during the war: a cross-sectional survey study.
PubMed Identifier: 41506773
author list: Kovalchuk N, Zinchuk A, Beznosenko A, Semikov R, Poylin V, Vash-Margita A, Mims M, Davis D, Uboha N, Suchowerska N, Iakovenko V, Hart J, Poznansky M, Kacharian A, Kizub D, Melnitchouk S, Melnitchouk N
published in: BMJ open
information resource reference: Impact of international observerships on Ukrainian healthcare professionals during the war: a cross-sectional survey study. BMJ Open. 2026 Jan 08; 16(1):e109052.
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publication date: 2026-01-08T00:00:00
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Authorship 257631
type: Authorship
author rank in publication: 3
linked author: Poznansky, Mark
linked information resource: Fugetaxis: active movement of leukocytes away from a chemokinetic agent.

Authorship 417867
type: Authorship
author rank in publication: 6
linked author: Poznansky, Mark
linked information resource: Patients unaware of their HIV status present to inner city accident and emergency department with respiratory complications.

Lecturer on Pediatrics, Part-time
is primary position: true
position in department: Pediatrics
position in division: Nephrology
sort order: 1
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HR job title: Lecturer on Pediatrics, Part-time
position in organization: Boston Children's Hospital

Authorship 35573
type: Authorship
author rank in publication: 6
linked author: Poznansky, Mark
linked information resource: A CXCR4-dependent chemorepellent signal contributes to the emigration of mature single-positive CD4 cells from the fetal thymus.

Authorship 433173
type: Authorship
author rank in publication: 6
linked author: Poznansky, Mark
linked information resource: Efficiency of a high-titer retroviral vector for gene transfer into skeletal myoblasts.

Authorship 771542
type: Authorship
author rank in publication: 4
linked author: Poznansky, Mark
linked information resource: Laser vaccine adjuvants. History, progress, and potential.

Laser vaccine adjuvants. History, progress, and potential.
PubMed Identifier: 25424797
author list: Kashiwagi S, Brauns T, Gelfand J, Poznansky MC
published in: Human vaccines & immunotherapeutics
information resource reference: Laser vaccine adjuvants. History, progress, and potential. Hum Vaccin Immunother. 2014; 10(7):1892-907.
journal title abbreviation: Hum Vaccin Immunother
publication date: 2014-01-01T00:00:00
year: 2014
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 49391
type: Authorship
author rank in publication: 2
linked author: Poznansky, Mark
linked information resource: Reverse leukocyte migration can be attractive or repulsive.

Authorship 501419
type: Authorship
author rank in publication: 6
linked author: Poznansky, Mark
linked information resource: Stem cell engraftment at the endosteal niche is specified by the calcium-sensing receptor.

Authorship 522507
type: Authorship
author rank in publication: 2
linked author: Poznansky, Mark
linked information resource: Extracellular calcium elicits a chemokinetic response from monocytes in vitro and in vivo.

Authorship 84771
type: Authorship
author rank in publication: 1
linked author: Poznansky, Mark
linked information resource: The development of a gene therapy for HIV infection.

Authorship 267516
type: Authorship
author rank in publication: 1
linked author: Poznansky, Mark
linked information resource: HIV positive patients first presenting with an AIDS defining illness: characteristics and survival.

Authorship 324171
type: Authorship
author rank in publication: 1
linked author: Poznansky, Mark
linked information resource: Tissue source dictates lineage outcome of human fetal CD34(+)CD38(-) cells.

Authorship 86237
type: Authorship
author rank in publication: 1
linked author: Poznansky, Mark
linked information resource: The difference between human C3F and C3S results from a single amino acid change from an asparagine to an aspartate residue at position 1216 on the alpha chain of the complement component, C3.

Authorship 57882
type: Authorship
author rank in publication: 14
linked author: Poznansky, Mark
linked information resource: Neutrophil chemorepulsion in defined interleukin-8 gradients in vitro and in vivo.

Authorship 261785
type: Authorship
author rank in publication: 17
linked author: Poznansky, Mark
linked information resource: CXCL12/CXCR4 blockade induces multimodal antitumor effects that prolong survival in an immunocompetent mouse model of ovarian cancer.

Authorship 61011
type: Authorship
author rank in publication: 2
linked author: Poznansky, Mark
linked information resource: Characterization and functional studies of rheumatoid synovial mast cells. Activation by secretagogues, anti-IgE, and a histamine-releasing lymphokine.

Authorship 93287
type: Authorship
author rank in publication: 14
linked author: Poznansky, Mark
linked information resource: R5-SHIV induces multiple defects in T cell function during early infection of rhesus macaques including accumulation of T reg cells in lymph nodes.

Authorship 272218
type: Authorship
author rank in publication: 3
linked author: Poznansky, Mark
linked information resource: The in vivo effects of combination antiretroviral drug therapy on peripheral blood CD34+ cell colony-forming units from HIV type 1-infected patients.

Authorship 198364
type: Authorship
author rank in publication: 1
linked author: Poznansky, Mark
linked information resource: The difference between human C3F and C3S results from a single amino acid change from an asparagine to an aspartate residue at position 1216 on the alpha-chain of the complement component, C3.

Authorship 27060
type: Authorship
author rank in publication: 9
linked author: Poznansky, Mark
linked information resource: R5 clade C SHIV strains with tier 1 or 2 neutralization sensitivity: tools to dissect env evolution and to develop AIDS vaccines in primate models.

Authorship 308046
type: Authorship
author rank in publication: 4
linked author: Poznansky, Mark
linked information resource: Immune responses to HIV Gp120 that facilitate viral escape.

Authorship 362001
type: Authorship
author rank in publication: 1
linked author: Poznansky, Mark
linked information resource: Advantages in the use of L-asparaginase-albumin polymer as an antitumor agent.

Alginate encapsulant incorporating CXCL12 supports long-term allo- and xenoislet transplantation without systemic immune suppression.
PubMed Identifier: 25693473
author list: Chen T, Yuan J, Duncanson S, Hibert ML, Kodish BC, Mylavaganam G, Maker M, Li H, Sremac M, Santosuosso M, Forbes B, Kashiwagi S, Cao J, Lei J, Thomas M, Hartono C, Sachs D, Markmann J, Sambanis A, Poznansky MC
published in: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons
information resource reference: Alginate encapsulant incorporating CXCL12 supports long-term allo- and xenoislet transplantation without systemic immune suppression. Am J Transplant. 2015 Mar; 15(3):618-27.
journal title abbreviation: Am J Transplant
publication date: 2015-03-01T00:00:00
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type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 507629
type: Authorship
author rank in publication: 11
linked author: Poznansky, Mark
linked information resource: Bone marrow-derived B cells preserve ventricular function after acute myocardial infarction.

Authorship 309905
type: Authorship
author rank in publication: 1
linked author: Poznansky, Mark
linked information resource: Active movement of T cells away from a chemokine.

Authorship 316016
type: Authorship
author rank in publication: 2
linked author: Poznansky, Mark
linked information resource: Generation of a tissue-engineered thymic organoid.

Authorship 210694
type: Authorship
author rank in publication: 8
linked author: Poznansky, Mark
linked information resource: The efficacy of T cell-mediated immune responses is reduced by the envelope protein of the chimeric HIV-1/SIV-KB9 virus in vivo.

Authorship 280425
type: Authorship
author rank in publication: 1
linked author: Poznansky, Mark
linked information resource: Resistance to methylprednisolone in cultures of blood mononuclear cells from glucocorticoid-resistant asthmatic patients.

Authorship 337706
type: Authorship
author rank in publication: 11
linked author: Poznansky, Mark
linked information resource: Migration of antigen-specific T cells away from CXCR4-binding human immunodeficiency virus type 1 gp120.

Authorship 369199
type: Authorship
author rank in publication: 2
linked author: Poznansky, Mark
linked information resource: Naive and memory CD4? T cells in HIV eradication and immunization.

Authorship 788303
type: Authorship
author rank in publication: 20
linked author: Poznansky, Mark
linked information resource: Alginate encapsulant incorporating CXCL12 supports long-term allo- and xenoislet transplantation without systemic immune suppression.

Authorship 802474
type: Authorship
author rank in publication: 22
linked author: Poznansky, Mark
linked information resource: VaxCelerate II: rapid development of a self-assembling vaccine for Lassa fever.

VaxCelerate II: rapid development of a self-assembling vaccine for Lassa fever.
PubMed Identifier: 25483693
author list: Leblanc P, Moise L, Luza C, Chantaralawan K, Lezeau L, Yuan J, Field M, Richer D, Boyle C, Martin WD, Fishman JB, Berg EA, Baker D, Zeigler B, Mais DE, Taylor W, Coleman R, Warren HS, Gelfand JA, De Groot AS, Brauns T, Poznansky MC
published in: Human vaccines & immunotherapeutics
information resource reference: VaxCelerate II: rapid development of a self-assembling vaccine for Lassa fever. Hum Vaccin Immunother. 2014; 10(10):3022-38.
journal title abbreviation: Hum Vaccin Immunother
publication date: 2014-01-01T00:00:00
year: 2014
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 455223
type: Authorship
author rank in publication: 2
linked author: Poznansky, Mark
linked information resource: Vaccination of oncology patients: an effective tool and an opportunity not to be missed.

Authorship 497575
type: Authorship
author rank in publication: 1
linked author: Poznansky, Mark
linked information resource: Prevalence of HIV infection in patients attending an inner city accident and emergency department.

Authorship 361143
type: Authorship
author rank in publication: 17
linked author: Poznansky, Mark
linked information resource: Vascular normalizing doses of antiangiogenic treatment reprogram the immunosuppressive tumor microenvironment and enhance immunotherapy.

Authorship 380311
type: Authorship
author rank in publication: 15
linked author: Poznansky, Mark
linked information resource: Long-term survival of transplanted allogeneic cells engineered to express a T cell chemorepellent.

Human Neutrophils Are Primed by Chemoattractant Gradients for Blocking the Growth of Aspergillus fumigatus.
PubMed Identifier: 26272935
author list: Jones CN, Dimisko L, Forrest K, Judice K, Poznansky MC, Markmann JF, Vyas JM, Irimia D
published in: The Journal of infectious diseases
information resource reference: Human Neutrophils Are Primed by Chemoattractant Gradients for Blocking the Growth of Aspergillus fumigatus. J Infect Dis. 2016 Feb 01; 213(3):465-75.
journal title abbreviation: J Infect Dis
publication date: 2015-08-12T00:00:00
year: 2015
type: Academic Article
type: Article
type: Document
type: Information Resource

Sirbulescu, Ruxandra
eCommons Login: RFS13
first name: Ruxandra
last name: Sirbulescu
full name: Ruxandra F. Sirbulescu, Ph.D.
has faculty rank: Assistant Professor
Person ID: 144642
person in primary position: Assistant Professor of Neurology
type: Agent
type: Person
preferred title: Assistant Professor of Neurology

Authorship 855887
type: Authorship
author rank in publication: 5
linked author: Poznansky, Mark
linked information resource: Human Neutrophils Are Primed by Chemoattractant Gradients for Blocking the Growth of Aspergillus fumigatus.

Authorship 470246
type: Authorship
author rank in publication: 8
linked author: Poznansky, Mark
linked information resource: https://connects.catalyst.harvard.edu/Profiles/profile/840968

Authorship 483930
type: Authorship
author rank in publication: 5
linked author: Poznansky, Mark
linked information resource: Replication of human immunodeficiency virus type 1 in primary dendritic cell cultures.

Authorship 873022
type: Authorship
author rank in publication: 5
linked author: Poznansky, Mark
linked information resource: A Critical Reappraisal of Prolonged Neutropenia as a Risk Factor for Invasive Pulmonary Aspergillosis.

A Critical Reappraisal of Prolonged Neutropenia as a Risk Factor for Invasive Pulmonary Aspergillosis.
PubMed Identifier: 27006961
author list: Abers MS, Ghebremichael MS, Timmons AK, Warren HS, Poznansky MC, Vyas JM
published in: Open forum infectious diseases
information resource reference: A Critical Reappraisal of Prolonged Neutropenia as a Risk Factor for Invasive Pulmonary Aspergillosis. Open Forum Infect Dis. 2016 Jan; 3(1):ofw036.
journal title abbreviation: Open Forum Infect Dis
publication date: 2016-02-12T00:00:00
year: 2016
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 515985
type: Authorship
author rank in publication: 2
linked author: Poznansky, Mark
linked information resource: Survival and treatment of AIDS patients 1984-1993.

Authorship 92257
type: Authorship
author rank in publication: 14
linked author: Poznansky, Mark
linked information resource: X4 human immunodeficiency virus type 1 gp120 down-modulates expression and immunogenicity of codelivered antigens.

Assistant Professor
sort order: 2
type: Faculty Rank

Associate Professor
sort order: 1
type: Faculty Rank

Fellow or Post Doc
sort order: 6
type: Faculty Rank

Full Professor
sort order: 0
type: Faculty Rank

Lecturer
sort order: 3
type: Faculty Rank

Authorship 572570
type: Authorship
author rank in publication: 12
linked author: Poznansky, Mark
linked information resource: Correlation of CXCL12 expression and FoxP3+ cell infiltration with human papillomavirus infection and clinicopathological progression of cervical cancer.

Authorship 502026
type: Authorship
author rank in publication: 6
linked author: Poznansky, Mark
linked information resource: Microfluidic system for measuring neutrophil migratory responses to fast switches of chemical gradients.

Authorship 492753
type: Authorship
author rank in publication: 1
linked author: Poznansky, Mark
linked information resource: Inhibition of human immunodeficiency virus replication and growth advantage of CD4+ T cells from HIV-infected individuals that express intracellular antibodies against HIV-1 gp120 or Tat.

Authorship 549707
type: Authorship
author rank in publication: 2
linked author: Poznansky, Mark
linked information resource: T-lymphocyte development and models of thymopoietic reconstitution.

Novel agents for mitigation of radiation-induced pulmonary injury
end date: 2013-01-31
principal investigator name: HELD, KATHRYN DALE
start date: 2009-09-25
type: Grant
sponsor award id: RC1AI081282

Movement of Recipient T-Cells Away From an Allograft
end date: 2004-08-31
principal investigator name: POZNANSKY, MARK COLEMAN
start date: 2001-09-15
type: Grant
sponsor award id: R21AI049858

HIV-1 gp120 induced CTL chemorepulsion:dysregulation of migration &localization
end date: 2012-06-30
principal investigator name: POZNANSKY, MARK COLEMAN
start date: 2001-04-01
type: Grant
sponsor award id: R01AI049757

Principal Investigator
type: Researcher Role
researcher role of: Poznansky, Mark
contributes to: HIV-1 gp120 induced CTL chemorepulsion:dysregulation of migration &localization

Co-Principal Investigator
type: Researcher Role
researcher role of: Poznansky, Mark
contributes to: Novel agents for mitigation of radiation-induced pulmonary injury

Principal Investigator
type: Researcher Role
researcher role of: Poznansky, Mark
contributes to: Movement of Recipient T-Cells Away From an Allograft

Authorship 90651
type: Authorship
author rank in publication: 1
linked author: Poznansky, Mark
linked information resource: The rising prevalence of HIV-1 infection in patients attending an inner city accident and emergency department.

Authorship 320924
type: Authorship
author rank in publication: 8
linked author: Poznansky, Mark
linked information resource: Heterologous cells cooperate to augment stem cell migration, homing, and engraftment.

Authorship 406737
type: Authorship
author rank in publication: 1
linked author: Poznansky, Mark
linked information resource: Gene transfer into human lymphocytes by a defective human immunodeficiency virus type 1 vector.

Authorship 930639
type: Authorship
author rank in publication: 2
linked author: Poznansky, Mark
linked information resource: Semipermeable microcapsules containing catalase for enzyme replacement in acatalasaemic mice.

Authorship 933996
type: Authorship
author rank in publication: 3
linked author: Poznansky, Mark
linked information resource: Classification of Laser Vaccine Adjuvants.

Authorship 932399
type: Authorship
author rank in publication: 1
linked author: Poznansky, Mark
linked information resource: Transbilayer movement of cholesterol in dipalmitoyllecithin-cholesterol vesicles.

Semipermeable microcapsules containing catalase for enzyme replacement in acatalasaemic mice.
PubMed Identifier: 5648221
author list: Chang TM, Poznansky MJ
published in: Nature
information resource reference: Semipermeable microcapsules containing catalase for enzyme replacement in acatalasaemic mice. Nature. 1968 Apr 20; 218(5138):243-5.
journal title abbreviation: Nature
publication date: 1968-04-20T00:00:00
year: 1968
type: Academic Article
type: Article
type: Document
type: Information Resource

Transbilayer movement of cholesterol in dipalmitoyllecithin-cholesterol vesicles.
PubMed Identifier: 1250389
author list: Poznansky M, Lange Y
published in: Nature
information resource reference: Transbilayer movement of cholesterol in dipalmitoyllecithin-cholesterol vesicles. Nature. 1976 Feb 05; 259(5542):420-1.
journal title abbreviation: Nature
publication date: 1976-02-05T00:00:00
year: 1976
type: Academic Article
type: Article
type: Document
type: Information Resource

Classification of Laser Vaccine Adjuvants.
PubMed Identifier: 27104047
author list: Kashiwagi S, Brauns T, Poznansky MC
published in: Journal of vaccines & vaccination
information resource reference: Classification of Laser Vaccine Adjuvants. J Vaccines Vaccin. 2016 Feb; 7(1).
journal title abbreviation: J Vaccines Vaccin
publication date: 2016-02-12T00:00:00
year: 2016
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 954216
type: Authorship
author rank in publication: 4
linked author: Poznansky, Mark
linked information resource: Adult-Onset Still's Disease: Still a Serious Health Problem (a Case Report and Literature Review).

Adult-Onset Still's Disease: Still a Serious Health Problem (a Case Report and Literature Review).
PubMed Identifier: 28154368
author list: Agha-Abbaslou M, Bensaci AM, Dike O, Poznansky MC, Hyat A
published in: The American journal of case reports
information resource reference: Adult-Onset Still's Disease: Still a Serious Health Problem (a Case Report and Literature Review). Am J Case Rep. 2017 Feb 03; 18:119-124.
journal title abbreviation: Am J Case Rep
publication date: 2017-02-03T00:00:00
year: 2017
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 958194
type: Authorship
author rank in publication: 8
linked author: Poznansky, Mark
linked information resource: Biomechanically primed liver microtumor array as a high-throughput mechanopharmacological screening platform for stroma-reprogrammed combinatorial therapy.

Biomechanically primed liver microtumor array as a high-throughput mechanopharmacological screening platform for stroma-reprogrammed combinatorial therapy.
PubMed Identifier: 28182873
author list: Zhu L, Fan X, Wang B, Liu L, Yan X, Zhou L, Zeng Y, Poznansky MC, Wang L, Chen H, Du Y
published in: Biomaterials
information resource reference: Biomechanically primed liver microtumor array as a high-throughput mechanopharmacological screening platform for stroma-reprogrammed combinatorial therapy. Biomaterials. 2017 04; 124:12-24.
journal title abbreviation: Biomaterials
publication date: 2017-01-27T00:00:00
year: 2017
type: Academic Article
type: Article
type: Document
type: Information Resource

Efficient generation of human T cells from a tissue-engineered thymic organoid.
PubMed Identifier: 10888839
author list: Poznansky MC, Evans RH, Foxall RB, Olszak IT, Piascik AH, Hartman KE, Brander C, Meyer TH, Pykett MJ, Chabner KT, Kalams SA, Rosenzweig M, Scadden DT
published in: Nature biotechnology
information resource reference: Efficient generation of human T cells from a tissue-engineered thymic organoid. Nat Biotechnol. 2000 Jul; 18(7):729-34.
journal title abbreviation: Nat Biotechnol
publication date: 2000-07-01T00:00:00
year: 2000
type: Academic Article
type: Article
type: Document
type: Information Resource

Fugetaxis: active movement of leukocytes away from a chemokinetic agent.
PubMed Identifier: 16142473
author list: Vianello F, Olszak IT, Poznansky MC
published in: Journal of molecular medicine (Berlin, Germany)
information resource reference: Fugetaxis: active movement of leukocytes away from a chemokinetic agent. J Mol Med (Berl). 2005 Oct; 83(10):752-63.
journal title abbreviation: J Mol Med (Berl)
publication date: 2005-09-03T00:00:00
year: 2005
type: Academic Article
type: Article
type: Document
type: Information Resource

Isolation and transduction of CD34+ cells from small quantities of peripheral blood from HIV-1-infected patients not treated with hemopoietic growth factors.
PubMed Identifier: 10235508
author list: Adams GB, McMullen M, Turner S, Olszak IT, Scadden DT, McClure MO, Poznansky MC
published in: Journal of acquired immune deficiency syndromes (1999)
information resource reference: Isolation and transduction of CD34+ cells from small quantities of peripheral blood from HIV-1-infected patients not treated with hemopoietic growth factors. J Acquir Immune Defic Syndr. 1999 May 01; 21(1):1-8.
journal title abbreviation: J Acquir Immune Defic Syndr
publication date: 1999-05-01T00:00:00
year: 1999
type: Academic Article
type: Article
type: Document
type: Information Resource

Extracellular calcium elicits a chemokinetic response from monocytes in vitro and in vivo.
PubMed Identifier: 10792005
author list: Olszak IT, Poznansky MC, Evans RH, Olson D, Kos C, Pollak MR, Brown EM, Scadden DT
published in: The Journal of clinical investigation
information resource reference: Extracellular calcium elicits a chemokinetic response from monocytes in vitro and in vivo. J Clin Invest. 2000 May; 105(9):1299-305.
journal title abbreviation: J Clin Invest
publication date: 2000-05-01T00:00:00
year: 2000
type: Academic Article
type: Article
type: Document
type: Information Resource

Neutrophil chemorepulsion in defined interleukin-8 gradients in vitro and in vivo.
PubMed Identifier: 16365152
author list: Tharp WG, Yadav R, Irimia D, Upadhyaya A, Samadani A, Hurtado O, Liu SY, Munisamy S, Brainard DM, Mahon MJ, Nourshargh S, van Oudenaarden A, Toner MG, Poznansky MC
published in: Journal of leukocyte biology
information resource reference: Neutrophil chemorepulsion in defined interleukin-8 gradients in vitro and in vivo. J Leukoc Biol. 2006 Mar; 79(3):539-54.
journal title abbreviation: J Leukoc Biol
publication date: 2005-12-19T00:00:00
year: 2005
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 975931
type: Authorship
author rank in publication: 22
linked author: Poznansky, Mark
linked information resource: Semiconductor diode laser device adjuvanting intradermal vaccine.

Semiconductor diode laser device adjuvanting intradermal vaccine.
PubMed Identifier: 28365253
author list: Kimizuka Y, Callahan JJ, Huang Z, Morse K, Katagiri W, Shigeta A, Bronson R, Takeuchi S, Shimaoka Y, Chan MPK, Zeng Y, Li B, Chen H, Tan RYY, Dwyer C, Mulley T, Leblanc P, Goudie C, Gelfand J, Tsukada K, Brauns T, Poznansky MC, Bean D, Kashiwagi S
published in: Vaccine
information resource reference: Semiconductor diode laser device adjuvanting intradermal vaccine. Vaccine. 2017 04 25; 35(18):2404-2412.
journal title abbreviation: Vaccine
publication date: 2017-03-30T00:00:00
year: 2017
type: Academic Article
type: Article
type: Document
type: Information Resource

Thymocyte emigration is mediated by active movement away from stroma-derived factors.
PubMed Identifier: 11956248
author list: Poznansky MC, Olszak IT, Evans RH, Wang Z, Foxall RB, Olson DP, Weibrecht K, Luster AD, Scadden DT
published in: The Journal of clinical investigation
information resource reference: Thymocyte emigration is mediated by active movement away from stroma-derived factors. J Clin Invest. 2002 Apr; 109(8):1101-10.
journal title abbreviation: J Clin Invest
publication date: 2002-04-01T00:00:00
year: 2002
type: Academic Article
type: Article
type: Document
type: Information Resource

Inhibition of human immunodeficiency virus replication and growth advantage of CD4+ T cells from HIV-infected individuals that express intracellular antibodies against HIV-1 gp120 or Tat.
PubMed Identifier: 9525310
author list: Poznansky MC, Foxall R, Mhashilkar A, Coker R, Jones S, Ramstedt U, Marasco W
published in: Human gene therapy
information resource reference: Inhibition of human immunodeficiency virus replication and growth advantage of CD4+ T cells from HIV-infected individuals that express intracellular antibodies against HIV-1 gp120 or Tat. Hum Gene Ther. 1998 Mar 01; 9(4):487-96.
journal title abbreviation: Hum Gene Ther
publication date: 1998-03-01T00:00:00
year: 1998
type: Academic Article
type: Article
type: Document
type: Information Resource

Gene transfer into human lymphocytes by a defective human immunodeficiency virus type 1 vector.
PubMed Identifier: 1985215
author list: Poznansky M, Lever A, Bergeron L, Haseltine W, Sodroski J
published in: Journal of virology
information resource reference: Gene transfer into human lymphocytes by a defective human immunodeficiency virus type 1 vector. J Virol. 1991 Jan; 65(1):532-6.
journal title abbreviation: J Virol
publication date: 1991-01-01T00:00:00
year: 1991
type: Academic Article
type: Article
type: Document
type: Information Resource

A rapid method for quantitating the frequency of peripheral blood cells containing HIV-1 DNA.
PubMed Identifier: 1672549
author list: Poznansky MC, Walker B, Haseltine WA, Sodroski J, Langhoff E
published in: Journal of acquired immune deficiency syndromes
information resource reference: A rapid method for quantitating the frequency of peripheral blood cells containing HIV-1 DNA. J Acquir Immune Defic Syndr (1988). 1991; 4(4):368-73.
journal title abbreviation: J Acquir Immune Defic Syndr (1988)
publication date: 1991-01-01T00:00:00
year: 1991
type: Academic Article
type: Article
type: Document
type: Information Resource

Characterization and functional studies of rheumatoid synovial mast cells. Activation by secretagogues, anti-IgE, and a histamine-releasing lymphokine.
PubMed Identifier: 2427092
author list: Gruber B, Poznansky M, Boss E, Partin J, Gorevic P, Kaplan AP
published in: Arthritis and rheumatism
information resource reference: Characterization and functional studies of rheumatoid synovial mast cells. Activation by secretagogues, anti-IgE, and a histamine-releasing lymphokine. Arthritis Rheum. 1986 Aug; 29(8):944-55.
journal title abbreviation: Arthritis Rheum
publication date: 1986-08-01T00:00:00
year: 1986
type: Academic Article
type: Article
type: Document
type: Information Resource

Methods for quantitation of leukocyte chemotaxis and fugetaxis.
PubMed Identifier: 20379872
author list: Vianello F, Righi E, Poznansky MC
published in: Methods in molecular biology (Clifton, N.J.)
information resource reference: Methods for quantitation of leukocyte chemotaxis and fugetaxis. Methods Mol Biol. 2010; 616:115-24.
journal title abbreviation: Methods Mol Biol
publication date: 2010-01-01T00:00:00
year: 2010
type: Academic Article
type: Article
type: Document
type: Information Resource

Stem cell engraftment at the endosteal niche is specified by the calcium-sensing receptor.
PubMed Identifier: 16382241
author list: Adams GB, Chabner KT, Alley IR, Olson DP, Szczepiorkowski ZM, Poznansky MC, Kos CH, Pollak MR, Brown EM, Scadden DT
published in: Nature
information resource reference: Stem cell engraftment at the endosteal niche is specified by the calcium-sensing receptor. Nature. 2006 Feb 02; 439(7076):599-603.
journal title abbreviation: Nature
publication date: 2005-12-28T00:00:00
year: 2005
type: Academic Article
type: Article
type: Document
type: Information Resource

149 13th Street
type: Address
address line 1: Massachusetts General Hospital
address line 2: Vaccine and Immunotherapy Center
address line 3: 149 13th Street
city: Charlestown
postal code: 02129
state or province: MA

https://connects.catalyst.harvard.edu/Profiles/profile/840968
PubMed Identifier: 20214475
author list: Chenine AL, Siddappa NB, Kramer VG, Sciaranghella G, Rasmussen RA, Lee SJ, Santosuosso M, Poznansky MC, Velu V, Amara RR, Souder C, Anderson DC, Villinger F, Else JG, Novembre FJ, Strobert E, O'Neil SP, Secor WE, Ruprecht RM
published in: The Journal of infectious diseases
information resource reference: Relative transmissibility of an R5 clade C simian-human immunodeficiency virus across different mucosae in macaques parallels the relative risks of sexual HIV-1 transmission in humans via different routes. J Infect Dis. 2010 Apr 15; 201(8):1155-63.
journal title abbreviation: J Infect Dis
publication date: 2010-04-15T00:00:00
year: 2010
type: Academic Article
type: Article
type: Document
type: Information Resource
label: Relative transmissibility of an R5 clade C simian-human immunodeficiency virus across different mucosae in macaques parallels the relative risks of sexual HIV-1 transmission in humans via different routes.

Transendothelial movement of liposomes in vitro mediated by cancer cells, neutrophils or histamine.
PubMed Identifier: 15461929
author list: Antohe F, Lin L, Kao GY, Poznansky MJ, Allen TM
published in: Journal of liposome research
information resource reference: Transendothelial movement of liposomes in vitro mediated by cancer cells, neutrophils or histamine. J Liposome Res. 2004; 14(1-2):1-25.
journal title abbreviation: J Liposome Res
publication date: 2004-01-01T00:00:00
year: 2004
type: Academic Article
type: Article
type: Document
type: Information Resource

X4 human immunodeficiency virus type 1 gp120 down-modulates expression and immunogenicity of codelivered antigens.
PubMed Identifier: 19692474
author list: Hovav AH, Santosuosso M, Bivas-Benita M, Plair A, Cheng A, Elnekave M, Righi E, Chen T, Kashiwagi S, Panas MW, Xiang SH, Furmanov K, Letvin NL, Poznansky MC
published in: Journal of virology
information resource reference: X4 human immunodeficiency virus type 1 gp120 down-modulates expression and immunogenicity of codelivered antigens. J Virol. 2009 Nov; 83(21):10941-50.
journal title abbreviation: J Virol
publication date: 2009-08-19T00:00:00
year: 2009
type: Academic Article
type: Article
type: Document
type: Information Resource

Safety of intramyocardial injection of autologous bone marrow cells to treat myocardial ischemia in pigs.
PubMed Identifier: 16945820
author list: Goodchild T, Pang W, Tondato F, Cui J, Otsuka Y, Frowein S, Ungs M, Robinson K, Poznansky M, Chronos N
published in: Cardiovascular revascularization medicine : including molecular interventions
information resource reference: Safety of intramyocardial injection of autologous bone marrow cells to treat myocardial ischemia in pigs. Cardiovasc Revasc Med. 2006 Jul-Sep; 7(3):136-45.
journal title abbreviation: Cardiovasc Revasc Med
publication date: 2006-07-01T00:00:00
year: 2006
type: Academic Article
type: Article
type: Document
type: Information Resource

HIV-1 envelope protein gp120 is present at high concentrations in secondary lymphoid organs of individuals with chronic HIV-1 infection.
PubMed Identifier: 19698075
author list: Santosuosso M, Righi E, Lindstrom V, Leblanc PR, Poznansky MC
published in: The Journal of infectious diseases
information resource reference: HIV-1 envelope protein gp120 is present at high concentrations in secondary lymphoid organs of individuals with chronic HIV-1 infection. J Infect Dis. 2009 Oct 01; 200(7):1050-3.
journal title abbreviation: J Infect Dis
publication date: 2009-10-01T00:00:00
year: 2009
type: Academic Article
type: Article
type: Document
type: Information Resource

The difference between human C3F and C3S results from a single amino acid change from an asparagine to an aspartate residue at position 1216 on the alpha chain of the complement component, C3.
PubMed Identifier: 2584723
author list: Poznansky MC, Clissold PM, Lachmann PJ
published in: Journal of immunology (Baltimore, Md. : 1950)
information resource reference: The difference between human C3F and C3S results from a single amino acid change from an asparagine to an aspartate residue at position 1216 on the alpha chain of the complement component, C3. J Immunol. 1989 Dec 01; 143(11):3860-2.
journal title abbreviation: J Immunol
publication date: 1989-12-01T00:00:00
year: 1989
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1007358
type: Authorship
author rank in publication: 4
linked author: Poznansky, Mark
linked information resource: CXCR4 blockade with AMD3100 enhances Taxol chemotherapy to limit ovarian cancer cell growth.

Authorship 1006664
type: Authorship
author rank in publication: 22
linked author: Poznansky, Mark
linked information resource: Near-Infrared 1064 nm Laser Modulates Migratory Dendritic Cells To Augment the Immune Response to Intradermal Influenza Vaccine.

Near-Infrared 1064 nm Laser Modulates Migratory Dendritic Cells To Augment the Immune Response to Intradermal Influenza Vaccine.
PubMed Identifier: 28710250
author list: Morse K, Kimizuka Y, Chan MPK, Shibata M, Shimaoka Y, Takeuchi S, Forbes B, Nirschl C, Li B, Zeng Y, Bronson RT, Katagiri W, Shigeta A, Sîrbulescu RF, Chen H, Tan RYY, Tsukada K, Brauns T, Gelfand J, Sluder A, Locascio JJ, Poznansky MC, Anandasabapathy N, Kashiwagi S
published in: Journal of immunology (Baltimore, Md. : 1950)
information resource reference: Near-Infrared 1064 nm Laser Modulates Migratory Dendritic Cells To Augment the Immune Response to Intradermal Influenza Vaccine. J Immunol. 2017 08 15; 199(4):1319-1332.
journal title abbreviation: J Immunol
publication date: 2017-07-14T00:00:00
year: 2017
type: Academic Article
type: Article
type: Document
type: Information Resource

CXCR4 blockade with AMD3100 enhances Taxol chemotherapy to limit ovarian cancer cell growth.
PubMed Identifier: 28817386
author list: Reeves PM, Abbaslou MA, Kools FRW, Poznansky MC
published in: Anti-cancer drugs
information resource reference: CXCR4 blockade with AMD3100 enhances Taxol chemotherapy to limit ovarian cancer cell growth. Anticancer Drugs. 2017 10; 28(9):935-942.
journal title abbreviation: Anticancer Drugs
publication date: 2017-10-01T00:00:00
year: 2017
type: Academic Article
type: Article
type: Document
type: Information Resource

Microfluidic system for measuring neutrophil migratory responses to fast switches of chemical gradients.
PubMed Identifier: 16450027
author list: Irimia D, Liu SY, Tharp WG, Samadani A, Toner M, Poznansky MC
published in: Lab on a chip
information resource reference: Microfluidic system for measuring neutrophil migratory responses to fast switches of chemical gradients. Lab Chip. 2006 Feb; 6(2):191-8.
journal title abbreviation: Lab Chip
publication date: 2005-12-23T00:00:00
year: 2005
type: Academic Article
type: Article
type: Document
type: Information Resource

The in vivo effects of combination antiretroviral drug therapy on peripheral blood CD34+ cell colony-forming units from HIV type 1-infected patients.
PubMed Identifier: 10221532
author list: Adams GB, Pym AS, Poznansky MC, McClure MO, Weber JN
published in: AIDS research and human retroviruses
information resource reference: The in vivo effects of combination antiretroviral drug therapy on peripheral blood CD34+ cell colony-forming units from HIV type 1-infected patients. AIDS Res Hum Retroviruses. 1999 Apr 10; 15(6):551-9.
journal title abbreviation: AIDS Res Hum Retroviruses
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Authorship 1012989
type: Authorship
author rank in publication: 14
linked author: Poznansky, Mark
linked information resource: Mature B cells accelerate wound healing after acute and chronic diabetic skin lesions.

Authorship 1012609
type: Authorship
author rank in publication: 5
linked author: Poznansky, Mark
linked information resource: Q-vaxcelerate: A distributed development approach for a new Coxiella burnetii vaccine.

Q-vaxcelerate: A distributed development approach for a new Coxiella burnetii vaccine.
PubMed Identifier: 28933682
author list: Reeves PM, Paul SR, Sluder AE, Brauns TA, Poznansky MC
published in: Human vaccines & immunotherapeutics
information resource reference: Q-vaxcelerate: A distributed development approach for a new Coxiella burnetii vaccine. Hum Vaccin Immunother. 2017 12 02; 13(12):2977-2981.
journal title abbreviation: Hum Vaccin Immunother
publication date: 2017-09-21T00:00:00
year: 2017
type: Academic Article
type: Article
type: Document
type: Information Resource

Mature B cells accelerate wound healing after acute and chronic diabetic skin lesions.
PubMed Identifier: 28922523
author list: Sîrbulescu RF, Boehm CK, Soon E, Wilks MQ, Ilies I, Yuan H, Maxner B, Chronos N, Kaittanis C, Normandin MD, El Fakhri G, Orgill DP, Sluder AE, Poznansky MC
published in: Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society
information resource reference: Mature B cells accelerate wound healing after acute and chronic diabetic skin lesions. Wound Repair Regen. 2017 09; 25(5):774-791.
journal title abbreviation: Wound Repair Regen
publication date: 2017-10-17T00:00:00
year: 2017
type: Academic Article
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type: Document
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Bone marrow-derived B cells preserve ventricular function after acute myocardial infarction.
PubMed Identifier: 19850263
author list: Goodchild TT, Robinson KA, Pang W, Tondato F, Cui J, Arrington J, Godwin L, Ungs M, Carlesso N, Weich N, Poznansky MC, Chronos NA
published in: JACC. Cardiovascular interventions
information resource reference: Bone marrow-derived B cells preserve ventricular function after acute myocardial infarction. JACC Cardiovasc Interv. 2009 Oct; 2(10):1005-16.
journal title abbreviation: JACC Cardiovasc Interv
publication date: 2009-10-01T00:00:00
year: 2009
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type: Article
type: Document
type: Information Resource

Authorship 1015001
type: Authorship
author rank in publication: 17
linked author: Poznansky, Mark
linked information resource: PD-1 Expression in Head and Neck Squamous Cell Carcinomas Derives Primarily from Functionally Anergic CD4+ TILs in the Presence of PD-L1+ TAMs.

PD-1 Expression in Head and Neck Squamous Cell Carcinomas Derives Primarily from Functionally Anergic CD4+ TILs in the Presence of PD-L1+ TAMs.
PubMed Identifier: 28947422
author list: Mattox AK, Lee J, Westra WH, Pierce RH, Ghossein R, Faquin WC, Diefenbach TJ, Morris LG, Lin DT, Wirth LJ, Lefranc-Torres A, Ishida E, Chakravarty PD, Johnson L, Zeng YC, Chen H, Poznansky MC, Iyengar NM, Pai SI
published in: Cancer research
information resource reference: PD-1 Expression in Head and Neck Squamous Cell Carcinomas Derives Primarily from Functionally Anergic CD4+ TILs in the Presence of PD-L1+ TAMs. Cancer Res. 2017 11 15; 77(22):6365-6374.
journal title abbreviation: Cancer Res
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year: 2017
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Vascular normalizing doses of antiangiogenic treatment reprogram the immunosuppressive tumor microenvironment and enhance immunotherapy.
PubMed Identifier: 23045683
author list: Huang Y, Yuan J, Righi E, Kamoun WS, Ancukiewicz M, Nezivar J, Santosuosso M, Martin JD, Martin MR, Vianello F, Leblanc P, Munn LL, Huang P, Duda DG, Fukumura D, Jain RK, Poznansky MC
published in: Proceedings of the National Academy of Sciences of the United States of America
information resource reference: Vascular normalizing doses of antiangiogenic treatment reprogram the immunosuppressive tumor microenvironment and enhance immunotherapy. Proc Natl Acad Sci U S A. 2012 Oct 23; 109(43):17561-6.
journal title abbreviation: Proc Natl Acad Sci U S A
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year: 2012
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Resistance to methylprednisolone in cultures of blood mononuclear cells from glucocorticoid-resistant asthmatic patients.
PubMed Identifier: 6488705
author list: Poznansky MC, Gordon AC, Douglas JG, Krajewski AS, Wyllie AH, Grant IW
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Tissue source dictates lineage outcome of human fetal CD34(+)CD38(-) cells.
PubMed Identifier: 11378272
author list: Poznansky MC, Olszak IT, Foxall RB, Piascik A, Adams GB, Evans RH, Cheng T, Scadden DT
published in: Experimental hematology
information resource reference: Tissue source dictates lineage outcome of human fetal CD34(+)CD38(-) cells. Exp Hematol. 2001 Jun; 29(6):766-74.
journal title abbreviation: Exp Hematol
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Long-term survival of transplanted allogeneic cells engineered to express a T cell chemorepellent.
PubMed Identifier: 17264814
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published in: Transplantation
information resource reference: Long-term survival of transplanted allogeneic cells engineered to express a T cell chemorepellent. Transplantation. 2007 Jan 27; 83(2):174-83.
journal title abbreviation: Transplantation
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Replication of human immunodeficiency virus type 1 in primary dendritic cell cultures.
PubMed Identifier: 1910172
author list: Langhoff E, Terwilliger EF, Bos HJ, Kalland KH, Poznansky MC, Bacon OM, Haseltine WA
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Immune responses to HIV Gp120 that facilitate viral escape.
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author list: Stevceva L, Yoon V, Anastasiades D, Poznansky MC
published in: Current HIV research
information resource reference: Immune responses to HIV Gp120 that facilitate viral escape. Curr HIV Res. 2007 Jan; 5(1):47-54.
journal title abbreviation: Curr HIV Res
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Vaccination of oncology patients: an effective tool and an opportunity not to be missed.
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journal title abbreviation: Oncologist
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Accelerated vaccine development against emerging infectious diseases.
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author list: Leblanc PR, Yuan J, Brauns T, Gelfand JA, Poznansky MC
published in: Human vaccines & immunotherapeutics
information resource reference: Accelerated vaccine development against emerging infectious diseases. Hum Vaccin Immunother. 2012 Jul; 8(7):1010-2.
journal title abbreviation: Hum Vaccin Immunother
publication date: 2012-07-01T00:00:00
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Application and utility of mass cytometry in vaccine development.
PubMed Identifier: 29092906
author list: Reeves PM, Sluder AE, Paul SR, Scholzen A, Kashiwagi S, Poznansky MC
published in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology
information resource reference: Application and utility of mass cytometry in vaccine development. FASEB J. 2018 01; 32(1):5-15.
journal title abbreviation: FASEB J
publication date: 2017-11-01T00:00:00
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Authorship 1023028
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author rank in publication: 6
linked author: Poznansky, Mark
linked information resource: Application and utility of mass cytometry in vaccine development.

Authorship 1023009
type: Authorship
author rank in publication: 1
linked author: Poznansky, Mark
linked information resource: Enzyme replacement therapy in fibroblasts from a patient with cholesteryl ester storage disease.

Enzyme replacement therapy in fibroblasts from a patient with cholesteryl ester storage disease.
PubMed Identifier: 2644147
author list: Poznansky MJ, Hutchison SK, Davis PJ
published in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology
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Survival and treatment of AIDS patients 1984-1993.
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journal title abbreviation: Genitourin Med
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Heterologous cells cooperate to augment stem cell migration, homing, and engraftment.
PubMed Identifier: 12393569
author list: Adams GB, Chabner KT, Foxall RB, Weibrecht KW, Rodrigues NP, Dombkowski D, Fallon R, Poznansky MC, Scadden DT
published in: Blood
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journal title abbreviation: Blood
publication date: 2002-08-22T00:00:00
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Authorship 1031491
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author rank in publication: 8
linked author: Poznansky, Mark
linked information resource: Ruxolitinib sensitizes ovarian cancer to reduced dose Taxol, limits tumor growth and improves survival in immune competent mice.

Ruxolitinib sensitizes ovarian cancer to reduced dose Taxol, limits tumor growth and improves survival in immune competent mice.
PubMed Identifier: 29212208
author list: Reeves PM, Abbaslou MA, Kools FRW, Vutipongsatorn K, Tong X, Gavegnano C, Schinazi RF, Poznansky MC
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information resource reference: Ruxolitinib sensitizes ovarian cancer to reduced dose Taxol, limits tumor growth and improves survival in immune competent mice. Oncotarget. 2017 11 07; 8(55):94040-94053.
journal title abbreviation: Oncotarget
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R5-SHIV induces multiple defects in T cell function during early infection of rhesus macaques including accumulation of T reg cells in lymph nodes.
PubMed Identifier: 21483689
author list: Santosuosso M, Righi E, Hill ED, Leblanc PR, Kodish B, Mylvaganam HN, Siddappa NB, Stevceva L, Hu SL, Ghebremichael M, Chenine AL, Hovav AH, Ruprecht RM, Poznansky MC
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A cellular abnormality in glucocorticoid resistant asthma.
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R5 clade C SHIV strains with tier 1 or 2 neutralization sensitivity: tools to dissect env evolution and to develop AIDS vaccines in primate models.
PubMed Identifier: 20657739
author list: Siddappa NB, Watkins JD, Wassermann KJ, Song R, Wang W, Kramer VG, Lakhashe S, Santosuosso M, Poznansky MC, Novembre FJ, Villinger F, Else JG, Montefiori DC, Rasmussen RA, Ruprecht RM
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information resource reference: R5 clade C SHIV strains with tier 1 or 2 neutralization sensitivity: tools to dissect env evolution and to develop AIDS vaccines in primate models. PLoS One. 2010 Jul 21; 5(7):e11689.
journal title abbreviation: PLoS One
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The rising prevalence of HIV-1 infection in patients attending an inner city accident and emergency department.
PubMed Identifier: 8947806
author list: Poznansky MC, Walters J, Cruikshank A, Pollock R, Dendrowskyj P, Lewis K, Parry JV, Fothergill J, Weber J
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Murine B16 melanomas expressing high levels of the chemokine stromal-derived factor-1/CXCL12 induce tumor-specific T cell chemorepulsion and escape from immune control.
PubMed Identifier: 16493048
author list: Vianello F, Papeta N, Chen T, Kraft P, White N, Hart WK, Kircher MF, Swart E, Rhee S, Palù G, Irimia D, Toner M, Weissleder R, Poznansky MC
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The development of a gene therapy for HIV infection.
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