Dr. Nira Pollock, MD, PhD, D(ABMM) is the Co-Director of the Infectious Diseases Diagnostic Laboratory in the Department of Laboratory Medicine at Boston Children’s Hospital. She is also a faculty member of the Division of Infectious Diseases at BIDMC. She is an Associate Professor of both Pathology and Medicine at Harvard Medical School. Dr. Pollock is an expert in the development and evaluation of novel diagnostics for infectious diseases, with experience ranging from early proof of principle laboratory demonstration through translation to field implementation. Her diagnostics research has spanned a range of diseases including active and latent tuberculosis, C. difficile infection, influenza, malaria, Lyme disease, STDs, Ebola virus disease, HCV, and COVID-19. Her research has also involved a wide range of technologies, from simple paper-based lateral flow and microfluidic platforms to novel automated platforms for protein and nucleic acid detection, and a wide range of testing scenarios, from the high-complexity molecular laboratory to point-of-care testing (including in resource-limited and outbreak settings). Since 2023, she has worked part-time as a Senior Scientific Advisor for Diagnostic Development Strategy for the National Institute of Biomedical Imaging and Bioengineering at NIH, providing guidance to RADx/ITAP programs for diagnostic development and assisting with interagency pandemic preparedness efforts. Dr. Pollock is a member of the American Society of Clinical Investigation and a fellow of the Infectious Diseases Society of America (IDSA).
Pollock NR, Banz A, Chen X, Williams D, Xu H, Cuddemi CA, Cui AX, Perrotta M, Alhassan E, Riou B, Lantz A, Miller MA, Kelly CP
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
Comparison of Clostridioides difficile Stool Toxin Concentrations in Adults With Symptomatic Infection and Asymptomatic Carriage Using an Ultrasensitive Quantitative Immunoassay. Clin Infect Dis. 2019 01 01; 68(1):78-86.
Comparison of Clostridioides difficile Stool Toxin Concentrations in Adults With Symptomatic Infection and Asymptomatic Carriage Using an Ultrasensitive Quantitative Immunoassay.
Specimen dilution increases the diagnostic utility of the gen-probe mycobacterium tuberculosis direct test. Am J Clin Pathol. 2006 Jul; 126(1):142-7.
Specimen dilution increases the diagnostic utility of the gen-probe mycobacterium tuberculosis direct test.
Reconstitution of Microtubule-based Organelle Transport Using Factors Purified from Dictyostelium
Reconstitution of Microtubule-based Organelle Transport Using Factors Purified from Dictyostelium. 1999.
Low yield of chest radiography in a large tuberculosis screening program. Radiology. 2010 Sep; 256(3):998-1004.
Low yield of chest radiography in a large tuberculosis screening program.
The Cost-effectiveness of a Point-of-Care Paper Transaminase Test for Monitoring Treatment of HIV/TB Co-Infected Persons. Open Forum Infect Dis. 2017; 4(4):ofx194.
The Cost-effectiveness of a Point-of-Care Paper Transaminase Test for Monitoring Treatment of HIV/TB Co-Infected Persons.
N. Pollock, A. Sloutsky, S. Joshi, M. Wong, and E. Nardell
Presented at the International Union Against Tuberculosis and Lung Disease (IUATLD) Conference and Global Symposium on Interferon-gamma Assays, Vancouver, Canada, February 2007
Screening Health Care Workers (HCW) with Quantiferon-Gold: Possible False Negative Results in HCW with High Pre-Test Probability of Latent Tuberculosis Infection. Presented at the International Union Against Tuberculosis and Lung Disease (IUATLD) Conference and Global Symposium on Interferon-gamma Assays, Vancouver, Canada, February 2007. 2007.
Screening Health Care Workers (HCW) with Quantiferon-Gold: Possible False Negative Results in HCW with High Pre-Test Probability of Latent Tuberculosis Infection
Pollock N, de Hostos EL, Turck CW, Vale RD
Reconstitution of membrane transport powered by a novel dimeric kinesin motor of the Unc104/KIF1A family purified from Dictyostelium. J Cell Biol. 1999 Nov 01; 147(3):493-506.
Reconstitution of membrane transport powered by a novel dimeric kinesin motor of the Unc104/KIF1A family purified from Dictyostelium.
Professor of Global Health and Social Medicine
Maude and Lillian Presley Professor of Microbiology and Immunobiology, Emeritus
Kelly CP, Chen X, Williams D, Xu H, Cuddemi CA, Daugherty K, Barrett C, Miller M, Foussadier A, Lantz A, Banz A, Pollock NR
Host Immune Markers Distinguish Clostridioides difficile Infection From Asymptomatic Carriage and Non-C. difficile Diarrhea. Clin Infect Dis. 2020 03 03; 70(6):1083-1093.
Host Immune Markers Distinguish Clostridioides difficile Infection From Asymptomatic Carriage and Non-C. difficile Diarrhea.
Assistant Professor of Medicine, Part-time
Mesman AW, Soto M, Coit J, Calderon R, Aliaga J, Pollock NR, Mendoza M, Mestanza FM, Mendoza CJ, Murray MB, Lecca L, Holmberg R, Franke MF
Detection of Mycobacterium tuberculosis in pediatric stool samples using TruTip technology. BMC Infect Dis. 2019 Jun 27; 19(1):563.
Detection of Mycobacterium tuberculosis in pediatric stool samples using TruTip technology.
Lin Q, Pollock NR, Banz A, Lantz A, Xu H, Gu L, Gerding DN, Garey KW, Gonzales-Luna AJ, Zhao M, Song L, Duffy DC, Kelly CP, Chen X
Toxin A-Predominant Pathogenic Clostridioides difficile: A Novel Clinical Phenotype. Clin Infect Dis. 2020 06 10; 70(12):2628-2633.
Toxin A-Predominant Pathogenic Clostridioides difficile: A Novel Clinical Phenotype.
White NC, Mendo-Lopez R, Papamichael K, Cuddemi CA, Barrett C, Daugherty K, Pollock N, Kelly CP, Alonso CD
Laxative Use Does Not Preclude Diagnosis or Reduce Disease Severity in Clostridiodes difficile Infection. Clin Infect Dis. 2020 09 12; 71(6):1472-1478.
Laxative Use Does Not Preclude Diagnosis or Reduce Disease Severity in Clostridiodes difficile Infection.
Correction to: Detection of Mycobacterium tuberculosis in pediatric stool samples using TruTip technology. BMC Infect Dis. 2019 10 16; 19(1):856.
Correction to: Detection of Mycobacterium tuberculosis in pediatric stool samples using TruTip technology.
Diagnostic microbiology and infectious disease
Detection of mycobacterial lipoarabinomannan in serum for diagnosis of active tuberculosis. Diagn Microbiol Infect Dis. 2020 Feb; 96(2):114937.
Detection of mycobacterial lipoarabinomannan in serum for diagnosis of active tuberculosis.
Bulterys MA, Wagner B, Redard-Jacot M, Suresh A, Pollock NR, Moreau E, Denkinger CM, Drain PK, Broger T
Point-Of-Care Urine LAM Tests for Tuberculosis Diagnosis: A Status Update. J Clin Med. 2019 Dec 31; 9(1).
Point-Of-Care Urine LAM Tests for Tuberculosis Diagnosis: A Status Update.
Lee RA, Al Dhaheri F, Pollock NR, Sharma TS
Assessment of the Clinical Utility of Plasma Metagenomic Next-Generation Sequencing in a Pediatric Hospital Population. J Clin Microbiol. 2020 06 24; 58(7).
Assessment of the Clinical Utility of Plasma Metagenomic Next-Generation Sequencing in a Pediatric Hospital Population.
Branda JA, Lemieux JE, Blair L, Ahmed AA, Hong DK, Bercovici S, Blauwkamp TA, Hollemon D, Ho C, Strle K, Damle NS, Lepore TJ, Pollock NR
Detection of Borrelia burgdorferi Cell-free DNA in Human Plasma Samples for Improved Diagnosis of Early Lyme Borreliosis. Clin Infect Dis. 2021 10 05; 73(7):e2355-e2361.
Detection of Borrelia burgdorferi Cell-free DNA in Human Plasma Samples for Improved Diagnosis of Early Lyme Borreliosis.
Flores JA, Calderón R, Mesman AW, Soto M, Coit J, Aliaga J, Mendoza M, Leon SR, Konda K, Mestanza FM, Mendoza CJ, Lecca L, Murray MB, Holmberg RC, Pollock NR, Franke MF
The Pediatric infectious disease journal
Detection of Mycobacterium Tuberculosis DNA in Buccal Swab Samples from Children in Lima, Peru. Pediatr Infect Dis J. 2020 11; 39(11):e376-e380.
Detection of Mycobacterium Tuberculosis DNA in Buccal Swab Samples from Children in Lima, Peru.
Lee RA, Puig H, Nguyen PQ, Angenent-Mari NM, Donghia NM, McGee JP, Dvorin JD, Klapperich CM, Pollock NR, Collins JJ
Proceedings of the National Academy of Sciences of the United States of America
Ultrasensitive CRISPR-based diagnostic for field-applicable detection of Plasmodium species in symptomatic and asymptomatic malaria. Proc Natl Acad Sci U S A. 2020 10 13; 117(41):25722-25731.
Ultrasensitive CRISPR-based diagnostic for field-applicable detection of Plasmodium species in symptomatic and asymptomatic malaria.
Kociolek LK, Muller WJ, Yee R, Dien Bard J, Brown CA, Revell PA, Wardell H, Savage TJ, Jung S, Dominguez S, Parikh BA, Jerris RC, Kehl SC, Campigotto A, Bender JM, Zheng X, Muscat E, Linam M, Abuogi L, Smith C, Graff K, Hernandez-Leyva A, Williams D, Pollock NR
Comparison of Upper Respiratory Viral Load Distributions in Asymptomatic and Symptomatic Children Diagnosed with SARS-CoV-2 Infection in Pediatric Hospital Testing Programs. J Clin Microbiol. 2020 12 17; 59(1).
Comparison of Upper Respiratory Viral Load Distributions in Asymptomatic and Symptomatic Children Diagnosed with SARS-CoV-2 Infection in Pediatric Hospital Testing Programs.
Sprague R, Warny K, Pollock N, Daugherty K, Lin Q, Xu H, Cuddemi C, Barrett C, Chen X, Banz A, Lantz A, Garey KW, Gonzales-Luna AJ, Alonso CD, Galvez JAV, Kelly CP
Absence of Toxemia in Clostridioides difficile Infection: Results from Ultrasensitive Toxin Assay of Serum. Dig Dis Sci. 2021 10; 66(10):3303-3306.
Absence of Toxemia in Clostridioides difficile Infection: Results from Ultrasensitive Toxin Assay of Serum.
Mesman AW, Calderon RI, Pollock NR, Soto M, Mendoza M, Coit J, Zhang Z, Aliaga J, Lecca L, Holmberg RC, Franke MF
Molecular detection of Mycobacterium tuberculosis from buccal swabs among adult in Peru. Sci Rep. 2020 12 17; 10(1):22231.
Molecular detection of Mycobacterium tuberculosis from buccal swabs among adult in Peru.
Pollock NR, Savage TJ, Wardell H, Lee RA, Mathew A, Stengelin M, Sigal GB
Correlation of SARS-CoV-2 Nucleocapsid Antigen and RNA Concentrations in Nasopharyngeal Samples from Children and Adults Using an Ultrasensitive and Quantitative Antigen Assay. J Clin Microbiol. 2021 03 19; 59(4).
Correlation of SARS-CoV-2 Nucleocapsid Antigen and RNA Concentrations in Nasopharyngeal Samples from Children and Adults Using an Ultrasensitive and Quantitative Antigen Assay.
Lee RA, Herigon JC, Benedetti A, Pollock NR, Denkinger CM
Performance of Saliva, Oropharyngeal Swabs, and Nasal Swabs for SARS-CoV-2 Molecular Detection: a Systematic Review and Meta-analysis. J Clin Microbiol. 2021 04 20; 59(5).
Performance of Saliva, Oropharyngeal Swabs, and Nasal Swabs for SARS-CoV-2 Molecular Detection: a Systematic Review and Meta-analysis.
Pollock NR, Jacobs JR, Tran K, Cranston AE, Smith S, O'Kane CY, Roady TJ, Moran A, Scarry A, Carroll M, Volinsky L, Perez G, Patel P, Gabriel S, Lennon NJ, Madoff LC, Brown C, Smole SC
Performance and Implementation Evaluation of the Abbott BinaxNOW Rapid Antigen Test in a High-Throughput Drive-Through Community Testing Site in Massachusetts. J Clin Microbiol. 2021 04 20; 59(5).
Performance and Implementation Evaluation of the Abbott BinaxNOW Rapid Antigen Test in a High-Throughput Drive-Through Community Testing Site in Massachusetts.
Cao Y, Wang L, Ke S, Villafuerte Gálvez JA, Pollock NR, Barrett C, Sprague R, Daugherty K, Xu H, Lin Q, Yao J, Chen Y, Kelly CP, Liu YY, Chen X
Fecal Mycobiota Combined With Host Immune Factors Distinguish Clostridioides difficile Infection From Asymptomatic Carriage. Gastroenterology. 2021 06; 160(7):2328-2339.e6.
Fecal Mycobiota Combined With Host Immune Factors Distinguish Clostridioides difficile Infection From Asymptomatic Carriage.
Humphries RM, Azar MM, Caliendo AM, Chou A, Colgrove RC, Fabre V, Ginocchio CC, Hanson KE, Hayden MK, Pillai DR, Pollock NR, Lee FM
To Test, Perchance to Diagnose: Practical Strategies for Severe Acute Respiratory Syndrome Coronavirus 2 Testing. Open Forum Infect Dis. 2021 Apr; 8(4):ofab095.
To Test, Perchance to Diagnose: Practical Strategies for Severe Acute Respiratory Syndrome Coronavirus 2 Testing.
Pollock NR, MacIntyre AT, Blauwkamp TA, Blair L, Ho C, Calderon R, Franke MF
The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease
Detection of Mycobacterium tuberculosis cell-free DNA to diagnose TB in pediatric and adult patients. Int J Tuberc Lung Dis. 2021 05 01; 25(5):403-405.
Detection of Mycobacterium tuberculosis cell-free DNA to diagnose TB in pediatric and adult patients.
Krüger LJ, Gaeddert M, Tobian F, Lainati F, Gottschalk C, Klein JAF, Schnitzler P, Kräusslich HG, Nikolai O, Lindner AK, Mockenhaupt FP, Seybold J, Corman VM, Drosten C, Pollock NR, Knorr B, Welker A, de Vos M, Sacks JA, Denkinger CM
The Abbott PanBio WHO emergency use listed, rapid, antigen-detecting point-of-care diagnostic test for SARS-CoV-2-Evaluation of the accuracy and ease-of-use. PLoS One. 2021; 16(5):e0247918.
The Abbott PanBio WHO emergency use listed, rapid, antigen-detecting point-of-care diagnostic test for SARS-CoV-2-Evaluation of the accuracy and ease-of-use.
Ke S, Pollock NR, Wang XW, Chen X, Daugherty K, Lin Q, Xu H, Garey KW, Gonzales-Luna AJ, Kelly CP, Liu YY
Integrating gut microbiome and host immune markers to understand the pathogenesis of Clostridioides difficile infection. Gut Microbes. 2021 Jan-Dec; 13(1):1-18.
Integrating gut microbiome and host immune markers to understand the pathogenesis of Clostridioides difficile infection.
Alonso CD, Papamichael K, Sprague R, Barrett C, Gonzales-Luna AJ, Daugherty K, Garey KW, Villafuerte-Gálvez J, Xu H, Lin Q, Wang L, Chen X, Pollock NR, Kelly CP
Humoral Immune Response to Clostridioides difficile Toxins A and B in Hospitalized Immunocompromised Patients With C difficile Infection. Open Forum Infect Dis. 2021 Jul; 8(7):ofab286.
Humoral Immune Response to Clostridioides difficile Toxins A and B in Hospitalized Immunocompromised Patients With C difficile Infection.
Pollock NR, Berlin D, Smole SC, Madoff LC, Brown C, Henderson K, Larsen E, Hay J, Gabriel S, Gawande AA, Lennon NJ
Implementation of SARS-CoV2 Screening in K-12 Schools Using In-School Pooled Molecular Testing and Deconvolution by Rapid Antigen Test. J Clin Microbiol. 2021 08 18; 59(9):e0112321.
Implementation of SARS-CoV2 Screening in K-12 Schools Using In-School Pooled Molecular Testing and Deconvolution by Rapid Antigen Test.
Nehl E, Heilman S, Ku D, Gottfried D, Farmer S, Mannino R, Tyburski E, Sullivan J, Suessmith A, Bassit L, Figueroa J, Wood A, Leong T, Rao A, Rogers B, Jerris R, Park S, Gonzalez M, Frediani J, Morris C, Levy J, Schoof N, Mavigner M, Roback J, Herzegh K, Saakadze N, Ingersoll J, Cheedarla N, Neish A, Hanberry B, Porter C, Esper A, Kempker R, Rebolledo P, McGuinness P, Balagadde F, Gore R, Koren A, Pollock N, Rogers E, Simin K, Hafer N, Picard MA, Ghezzi C, McManus D, Buchholz B, Rostad C, Claveria V, Ramachandra T, Wang YF, Washington C, Stone C, Griffiths M, Schinazi R, Chahroudi A, Vos M, Brand O, Martin G, Lam W
IEEE open journal of engineering in medicine and biology
The RADx Tech Test Verification Core and the ACME POCT in the Evaluation of COVID-19 Testing Devices: A Model for Progress and Change. IEEE Open J Eng Med Biol. 2021 Apr 28; 2:142-151.
The RADx Tech Test Verification Core and the ACME POCT in the Evaluation of COVID-19 Testing Devices: A Model for Progress and Change.
Pollock NR, Lee F, Ginocchio CC, Yao JD, Humphries RM
Considerations for Assessment and Deployment of Rapid Antigen Tests for Diagnosis of Coronavirus Disease 2019. Open Forum Infect Dis. 2021 Jun; 8(6):ofab110.
Considerations for Assessment and Deployment of Rapid Antigen Tests for Diagnosis of Coronavirus Disease 2019.
Pollock NR, Tran K, Jacobs JR, Cranston AE, Smith S, O'Kane CY, Roady TJ, Moran A, Scarry A, Carroll M, Volinsky L, Perez G, Patel P, Gabriel S, Lennon NJ, Madoff LC, Brown C, Smole SC
Performance and Operational Evaluation of the Access Bio CareStart Rapid Antigen Test in a High-Throughput Drive-Through Community Testing Site in Massachusetts. Open Forum Infect Dis. 2021 Jul; 8(7):ofab243.
Performance and Operational Evaluation of the Access Bio CareStart Rapid Antigen Test in a High-Throughput Drive-Through Community Testing Site in Massachusetts.
Brümmer LE, Katzenschlager S, Gaeddert M, Erdmann C, Schmitz S, Bota M, Grilli M, Larmann J, Weigand MA, Pollock NR, Macé A, Carmona S, Ongarello S, Sacks JA, Denkinger CM
Accuracy of novel antigen rapid diagnostics for SARS-CoV-2: A living systematic review and meta-analysis. PLoS Med. 2021 08; 18(8):e1003735.
Accuracy of novel antigen rapid diagnostics for SARS-CoV-2: A living systematic review and meta-analysis.
Krüger LJ, Klein JAF, Tobian F, Gaeddert M, Lainati F, Klemm S, Schnitzler P, Bartenschlager R, Cerikan B, Neufeldt CJ, Nikolai O, Lindner AK, Mockenhaupt FP, Seybold J, Jones TC, Corman VM, Pollock NR, Knorr B, Welker A, de Vos M, Sacks JA, Denkinger CM
Evaluation of accuracy, exclusivity, limit-of-detection and ease-of-use of LumiraDx™: An antigen-detecting point-of-care device for SARS-CoV-2. Infection. 2022 Apr; 50(2):395-406.
Evaluation of accuracy, exclusivity, limit-of-detection and ease-of-use of LumiraDx™: An antigen-detecting point-of-care device for SARS-CoV-2.
Ciaranello A, Goehringer C, Nelson SB, Ruark LJ, Pollock NR
Lessons Learned From Implementation of SARS-CoV-2 Screening in K-12 Public Schools in Massachusetts. Open Forum Infect Dis. 2021 Aug; 8(8):ofab287.
Lessons Learned From Implementation of SARS-CoV-2 Screening in K-12 Public Schools in Massachusetts.
Alonso CD, Kelly CP, Garey KW, Gonzales-Luna AJ, Williams D, Daugherty K, Cuddemi C, Villafuerte-Gálvez J, White NC, Chen X, Xu H, Sprague R, Barrett C, Miller M, Foussadier A, Lantz A, Banz A, Pollock NR
Ultrasensitive and Quantitative Toxin Measurement Correlates With Baseline Severity, Severe Outcomes, and Recurrence Among Hospitalized Patients With Clostridioides difficile Infection. Clin Infect Dis. 2022 07 06; 74(12):2142-2149.
Ultrasensitive and Quantitative Toxin Measurement Correlates With Baseline Severity, Severe Outcomes, and Recurrence Among Hospitalized Patients With Clostridioides difficile Infection.
Schwenk HT, Pollock NR, Vaughan-Malloy AM
Journal of the Pediatric Infectious Diseases Society
Pediatric Clostridioides difficile Infection: Diagnosis and Diagnostic Stewardship. J Pediatric Infect Dis Soc. 2021 Nov 17; 10(Supplement_3):S16-S21.
Pediatric Clostridioides difficile Infection: Diagnosis and Diagnostic Stewardship.
Campbell J, Pollock N, Sharon A, Sauer-Budge AF
Analytical methods : advancing methods and applications
Development of an automated on-chip bead-based ELISA platform. Anal Methods. 2015 Oct 07; 7(19):8472-8477.
Development of an automated on-chip bead-based ELISA platform.
Sigal GB, Novak T, Mathew A, Chou J, Zhang Y, Manjula N, Bathala P, Joe J, Padmanabhan N, Romero D, Allegri-Machado G, Joerger J, Loftis LL, Schwartz SP, Walker TC, Fitzgerald JC, Tarquinio KM, Zinter MS, Schuster JE, Halasa NB, Cullimore ML, Maddux AB, Staat MA, Irby K, Flori HR, Coates BM, Crandall H, Gertz SJ, Randolph AG, Pollock NR
medRxiv : the preprint server for health sciences
Measurement of SARS-CoV-2 antigens in plasma of pediatric patients with acute COVID-19 or MIS-C using an ultrasensitive and quantitative immunoassay. medRxiv. 2021 Dec 09.
Measurement of SARS-CoV-2 antigens in plasma of pediatric patients with acute COVID-19 or MIS-C using an ultrasensitive and quantitative immunoassay.
Krüger LJ, Tanuri A, Lindner AK, Gaeddert M, Köppel L, Tobian F, Brümmer LE, Klein JAF, Lainati F, Schnitzler P, Nikolai O, Mockenhaupt FP, Seybold J, Corman VM, Jones TC, Drosten C, Gottschalk C, Weber SF, Weber S, Ferreira OC, Mariani D, Dos Santos Nascimento ER, Pereira Pinto Castineiras TM, Galliez RM, Faffe DS, Leitão IC, Dos Santos Rodrigues C, Frauches TS, Nocchi KJCV, Feitosa NM, Ribeiro SS, Pollock NR, Knorr B, Welker A, de Vos M, Sacks J, Ongarello S, Denkinger CM
Accuracy and ease-of-use of seven point-of-care SARS-CoV-2 antigen-detecting tests: A multi-centre clinical evaluation. EBioMedicine. 2022 Jan; 75:103774.
Accuracy and ease-of-use of seven point-of-care SARS-CoV-2 antigen-detecting tests: A multi-centre clinical evaluation.
Pollock NR, Macovei L, Kanunfre K, Dhiman R, Restrepo BI, Zarate I, Pino PA, Mora-Guzman F, Fujiwara RT, Michel G, Kashino SS, Campos-Neto A
Validation of Mycobacterium tuberculosis Rv1681 protein as a diagnostic marker of active pulmonary tuberculosis. J Clin Microbiol. 2013; 5(51):1367-73.
Validation of Mycobacterium tuberculosis Rv1681 protein as a diagnostic marker of active pulmonary tuberculosis
Cao Q, Mahalanabis M, Chang J, Carey B, Hsieh C, Stanley A, Odell CA, Mitchell P, Feldman J, Pollock NR, Klapperich CM
Microfluidic chip for molecular amplification of influenza A RNA in human respiratory specimens. PLoS One. 2012; 3(7):e33176.
Microfluidic chip for molecular amplification of influenza A RNA in human respiratory specimens
A point-of-care paper-based fingerstick transaminase test: toward low-cost "lab-on-a-chip" technology for the developing world. Clin Gastroenterol Hepatol. 2013; 5(11):478-82.
A point-of-care paper-based fingerstick transaminase test: toward low-cost "lab-on-a-chip" technology for the developing world
Rosenbohm JM, Robson JM, Singh R, Lee R, Zhang JY, Klapperich CM, Pollock NR, Cabodi M
Rapid electrostatic DNA enrichment for sensitive detection of Trichomonas vaginalis in clinical urinary samples. Anal Methods. 2020 Feb 28; 12(8):1085-1093.
Rapid electrostatic DNA enrichment for sensitive detection of Trichomonas vaginalis in clinical urinary samples.
Lin J, Frediani JK, Damhorst GL, Sullivan JA, Westbrook A, McLendon K, Baugh TJ, O'Sick WH, Roback JD, Piantadosi AL, Waggoner JJ, Bassit L, Rao A, Greenleaf M, O'Neal JW, Swanson S, Pollock NR, Martin GS, Lam WA, Levy JM
Where is Omicron? Comparison of SARS-CoV-2 RT-PCR and Antigen Test Sensitivity at Commonly Sampled Anatomic Sites Over the Course of Disease. medRxiv. 2022 Feb 09.
Where is Omicron? Comparison of SARS-CoV-2 RT-PCR and Antigen Test Sensitivity at Commonly Sampled Anatomic Sites Over the Course of Disease.
Westbrook AL, Benedit LC, Frediani JK, Griffiths MA, Khan NY, Levy JM, Morris CR, Rostad CA, Stone CL, Sullivan J, Vos MB, Welsh J, Wood A, Martin GS, Lam W, Pollock NR
Predictive Value of Isolated Symptoms for Diagnosis of Severe Acute Respiratory Syndrome Coronavirus 2 Infection in Children Tested During Peak Circulation of the Delta Variant. Clin Infect Dis. 2022 09 30; 75(7):1131-1139.
Predictive Value of Isolated Symptoms for Diagnosis of Severe Acute Respiratory Syndrome Coronavirus 2 Infection in Children Tested During Peak Circulation of the Delta Variant.
Measurement of Severe Acute Respiratory Syndrome Coronavirus 2 Antigens in Plasma of Pediatric Patients With Acute Coronavirus Disease 2019 or Multisystem Inflammatory Syndrome in Children Using an Ultrasensitive and Quantitative Immunoassay. Clin Infect Dis. 2022 10 12; 75(8):1351-1358.
Measurement of Severe Acute Respiratory Syndrome Coronavirus 2 Antigens in Plasma of Pediatric Patients With Acute Coronavirus Disease 2019 or Multisystem Inflammatory Syndrome in Children Using an Ultrasensitive and Quantitative Immunoassay.
Alonso CD, Pollock NR, Garey KW, Gonzales-Luna AJ, Williams DN, Daugherty K, Cuddemi C, Villafuerte-Gálvez J, White NC, Chen X, Xu H, Sprague R, Barrett C, Miller M, Foussadier A, Lantz A, Banz A, Kelly CP
Higher In Vivo Fecal Concentrations of Clostridioides difficile Toxins A and B in Patients With North American Pulsed-Field Gel Electrophoresis Type 1/Ribotype 027 Strain Infection. Clin Infect Dis. 2022 11 30; 75(11):2019-2022.
Higher In Vivo Fecal Concentrations of Clostridioides difficile Toxins A and B in Patients With North American Pulsed-Field Gel Electrophoresis Type 1/Ribotype 027 Strain Infection.
Farmer S, Razin V, Peagler AF, Strickler S, Fain WB, Damhorst GL, Kempker RR, Pollock NR, Brand O, Seitter B, Heilman SS, Nehl EJ, Levy JM, Gottfried DS, Martin GS, Greenleaf M, Ku DN, Waggoner JJ, Iffrig E, Mannino RG, F Wang Y, Ortlund E, Sullivan J, Rebolledo PA, Clavería V, Roback JD, Benoit M, Stone C, Esper A, Frank F, Lam WA
Don't forget about human factors: Lessons learned from COVID-19 point-of-care testing. Cell Rep Methods. 2022 05 23; 2(5):100222.
Don't forget about human factors: Lessons learned from COVID-19 point-of-care testing.
Sandora TJ, Williams DN, Daugherty K, Geer C, Cuddemi C, Kociolek LK, Chen X, Xu H, Savage TJ, Banz A, Garey KW, Gonzales-Luna AJ, Kelly CP, Pollock NR
Stool Toxin Concentration Does Not Distinguish Clostridioides difficile Infection from Colonization in Children Less Than 3 Years of Age. J Pediatric Infect Dis Soc. 2022 Oct 25; 11(10):454-458.
Stool Toxin Concentration Does Not Distinguish Clostridioides difficile Infection from Colonization in Children Less Than 3 Years of Age.
Cao Y, Wang L, Ke S, Kelly CP, Pollock NR, Villafuerte Gálvez JA, Daugherty K, Xu H, Yao J, Chen Y, Liu YY, Chen X
Analysis of Intestinal Mycobiota of Patients with Clostridioides difficile Infection among a Prospective Inpatient Cohort. Microbiol Spectr. 2022 08 31; 10(4):e0136222.
Analysis of Intestinal Mycobiota of Patients with Clostridioides difficile Infection among a Prospective Inpatient Cohort.
Villafuerte Gálvez JA, Pollock NR, Alonso CD, Chen X, Xu H, Wang L, White N, Banz A, Miller M, Daugherty K, Gonzalez-Luna AJ, Barrett C, Sprague R, Garey KW, Kelly CP
Stool Interleukin-1ß Differentiates Clostridioides difficile Infection (CDI) From Asymptomatic Carriage and Non-CDI Diarrhea. Clin Infect Dis. 2023 02 08; 76(3):e1467-e1475.
Stool Interleukin-1ß Differentiates Clostridioides difficile Infection (CDI) From Asymptomatic Carriage and Non-CDI Diarrhea.
Brümmer LE, Katzenschlager S, McGrath S, Schmitz S, Gaeddert M, Erdmann C, Bota M, Grilli M, Larmann J, Weigand MA, Pollock NR, Macé A, Erkosar B, Carmona S, Sacks JA, Ongarello S, Denkinger CM
Accuracy of rapid point-of-care antigen-based diagnostics for SARS-CoV-2: An updated systematic review and meta-analysis with meta-regression analyzing influencing factors. PLoS Med. 2022 05; 19(5):e1004011.
Accuracy of rapid point-of-care antigen-based diagnostics for SARS-CoV-2: An updated systematic review and meta-analysis with meta-regression analyzing influencing factors.
Krüger LJ, Lindner AK, Gaeddert M, Tobian F, Klein J, Steinke S, Lainati F, Schnitzler P, Nikolai O, Mockenhaupt FP, Seybold J, Corman VM, Jones TC, Pollock NR, Knorr B, Welker A, Weber S, Sethurarnan N, Swaminathan J, Solomon H, Padmanaban A, Thirunarayan M, L P, de Vos M, Ongarello S, Sacks JA, Escadafal C, Denkinger CM
A Multicenter Clinical Diagnostic Accuracy Study of SureStatus, an Affordable, WHO Emergency Use-Listed, Rapid, Point-Of-Care Antigen-Detecting Diagnostic Test for SARS-CoV-2. Microbiol Spectr. 2022 10 26; 10(5):e0122922.
A Multicenter Clinical Diagnostic Accuracy Study of SureStatus, an Affordable, WHO Emergency Use-Listed, Rapid, Point-Of-Care Antigen-Detecting Diagnostic Test for SARS-CoV-2.
Rattan A, Joerger J, Williams D, Pollock NR
Similar SARS-CoV-2 Ct Value Distributions in Anterior Nares versus Nasopharyngeal Samples from Symptomatic Children during Delta and Omicron Surges. J Pediatric Infect Dis Soc. 2023 Feb 27; 12(2):109-112.
Similar SARS-CoV-2 Ct Value Distributions in Anterior Nares versus Nasopharyngeal Samples from Symptomatic Children during Delta and Omicron Surges.
Villafuerte-Gálvez JA, Pollock NR, Alonso CD, Chen X, Xu H, Wang L, White N, Banz A, Miller M, Daugherty K, Gonzalez-Luna AJ, Barrett C, Sprague R, Garey KW, Kelly CP
Sandora TJ, Kociolek LK, Williams DN, Daugherty K, Geer C, Cuddemi C, Chen X, Xu H, Savage TJ, Banz A, Garey KW, Gonzales-Luna AJ, Kelly CP, Pollock NR
Infection control and hospital epidemiology
Baseline stool toxin concentration is associated with risk of recurrence in children with Clostridioides difficile infection. Infect Control Hosp Epidemiol. 2023 09; 44(9):1403-1409.
Baseline stool toxin concentration is associated with risk of recurrence in children with Clostridioides difficile infection.
Rao A, Westbrook A, Bassit L, Parsons R, Fitts E, Greenleaf M, McLendon K, Sullivan JA, O'Sick W, Baugh T, Bowers HB, Frank F, Wang E, Le M, Frediani J, Roychoudhury P, Greninger AL, Jerris R, Pollock NR, Ortlund EA, Roback JD, Lam WA, Piantadosi A
Sensitivity of Rapid Antigen Tests Against SARS-CoV-2 Omicron and Delta Variants. medRxiv. 2023 Feb 10.
Sensitivity of Rapid Antigen Tests Against SARS-CoV-2 Omicron and Delta Variants.
Banegas M, Villafuerte-Gálvez J, Paredes R, Sprague R, Barrett C, Gonzales-Luna AJ, Daugherty K, Garey KW, Xu H, Lin Q, Wang L, Chen X, Pollock NR, Kelly CP, Alonso CD
Preservation of the Innate Immune Response to Clostridioides difficile Infection in Hospitalized Immunocompromised Patients. Open Forum Infect Dis. 2023 Mar; 10(3):ofad090.
Preservation of the Innate Immune Response to Clostridioides difficile Infection in Hospitalized Immunocompromised Patients.
Frediani JK, Parsons R, McLendon KB, Westbrook AL, Lam W, Martin G, Pollock NR
The New Normal: Delayed Peak SARS-CoV-2 Viral Loads Relative to Symptom Onset and Implications for COVID-19 Testing Programs. medRxiv. 2023 May 10.
The New Normal: Delayed Peak SARS-CoV-2 Viral Loads Relative to Symptom Onset and Implications for COVID-19 Testing Programs.
Nelson SB, Brenner IR, Homan E, Lee SB, Bongiorno C, Pollock NR, Ciaranello A
Evaluation of "Test to Return" after COVID-19 Diagnosis in a Massachusetts Public School District. J Sch Health. 2023 10; 93(10):877-882.
Evaluation of "Test to Return" after COVID-19 Diagnosis in a Massachusetts Public School District.
Nelson SB, Dugdale CM, Brenner IR, Crawford A, Bilinski A, Cosar D, Pollock NR, Ciaranello A
Prevalence and Risk Factors for School-Associated Transmission of SARS-CoV-2. JAMA Health Forum. 2023 08 04; 4(8):e232310.
Prevalence and Risk Factors for School-Associated Transmission of SARS-CoV-2.
Mesman AW, Calderon RI, Hauns L, Pollock NR, Mendoza M, Holmberg RC, Franke MF
Detection of Mycobacterium tuberculosis transrenal DNA in urine samples among adult patients in Peru. medRxiv. 2023 Jul 27.
Detection of Mycobacterium tuberculosis transrenal DNA in urine samples among adult patients in Peru.
The New Normal: Delayed Peak SARS-CoV-2 Viral Loads Relative to Symptom Onset and Implications for COVID-19 Testing Programs. Clin Infect Dis. 2024 02 17; 78(2):301-307.
Sensitivity of rapid antigen tests against SARS-CoV-2 Omicron and Delta variants. J Clin Microbiol. 2023 10 24; 61(10):e0013823.
Sensitivity of rapid antigen tests against SARS-CoV-2 Omicron and Delta variants.
Katzenschlager S, Brümmer LE, Schmitz S, Tolle H, Manten K, Gaeddert M, Erdmann C, Lindner A, Tobian F, Grilli M, Pollock NR, Macé A, Erkosar B, Carmona S, Ongarello S, Johnson CC, Sacks JA, Denkinger CM, Yerlikaya S
Comparing SARS-CoV-2 antigen-detection rapid diagnostic tests for COVID-19 self-testing/self-sampling with molecular and professional-use tests: a systematic review and meta-analysis. Sci Rep. 2023 12 11; 13(1):21913.
Comparing SARS-CoV-2 antigen-detection rapid diagnostic tests for COVID-19 self-testing/self-sampling with molecular and professional-use tests: a systematic review and meta-analysis.
Damhorst GL, Lin J, Frediani JK, Sullivan JA, Westbrook A, McLendon K, Baugh TJ, O'Sick WH, Roback JD, Piantadosi AL, Waggoner JJ, Bassit L, Rao A, Greenleaf M, O'Neal JW, Swanson S, Pollock NR, Martin GS, Lam WA, Levy JM
Comparison of RT-PCR and antigen test sensitivity across nasopharyngeal, nares, and oropharyngeal swab, and saliva sample types during the SARS-CoV-2 omicron variant. Heliyon. 2024 Mar 30; 10(6):e27188.
Comparison of RT-PCR and antigen test sensitivity across nasopharyngeal, nares, and oropharyngeal swab, and saliva sample types during the SARS-CoV-2 omicron variant.
Testing for SARS-CoV-2: lessons learned and current use cases. Clin Microbiol Rev. 2024 Jun 13; 37(2):e0007223.
Testing for SARS-CoV-2: lessons learned and current use cases.
Manten K, Katzenschlager S, Brümmer LE, Schmitz S, Gaeddert M, Erdmann C, Grilli M, Pollock NR, Macé A, Erkosar B, Carmona S, Ongarello S, Johnson CC, Sacks JA, Faehling V, Bornemann L, Weigand MA, Denkinger CM, Yerlikaya S
Clinical accuracy of instrument-based SARS-CoV-2 antigen diagnostic tests: a systematic review and meta-analysis. Virol J. 2024 04 29; 21(1):99.
Clinical accuracy of instrument-based SARS-CoV-2 antigen diagnostic tests: a systematic review and meta-analysis.
Ke S, Villafuerte Gálvez JA, Sun Z, Cao Y, Pollock NR, Chen X, Kelly CP, Liu YY
bioRxiv : the preprint server for biology
Rational Design of Live Biotherapeutic Products for the Prevention of Clostridioides difficile Infection. bioRxiv. 2024 May 02.
Rational Design of Live Biotherapeutic Products for the Prevention of Clostridioides difficile Infection.
Broger T, Marx FM, Theron G, Marais BJ, Nicol MP, Kerkhoff AD, Nathavitharana R, Huerga H, Gupta-Wright A, Kohli M, Nichols BE, Muyoyeta M, Meintjes G, Ruhwald M, Peeling RW, Pai NP, Pollock NR, Pai M, Cattamanchi A, Dowdy DW, Dewan P, Denkinger CM
Diagnostic yield as an important metric for the evaluation of novel tuberculosis tests: rationale and guidance for future research. Lancet Glob Health. 2024 07; 12(7):e1184-e1191.
Diagnostic yield as an important metric for the evaluation of novel tuberculosis tests: rationale and guidance for future research.
Detection of Mycobacterium tuberculosis transrenal DNA in urine samples among adults in Peru. Tuberculosis (Edinb). 2024 09; 148:102549.
Detection of Mycobacterium tuberculosis transrenal DNA in urine samples among adults in Peru.
Rational Design of Live Biotherapeutic Products for the Prevention of Clostridioides difficile Infection. J Infect Dis. 2025 Jul 11; 231(6):1392-1406.
Validation of Mycobacterium tuberculosis Rv1681 protein as a diagnostic marker of active pulmonary tuberculosis. J Clin Microbiol. 2013 May; 51(5):1367-73.
Validation of Mycobacterium tuberculosis Rv1681 protein as a diagnostic marker of active pulmonary tuberculosis.
Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association
A point-of-care paper-based fingerstick transaminase test: toward low-cost "lab-on-a-chip" technology for the developing world. Clin Gastroenterol Hepatol. 2013 May; 11(5):478-82.
A point-of-care paper-based fingerstick transaminase test: toward low-cost "lab-on-a-chip" technology for the developing world.
Pollock NR, McGray S, Colby DJ, Noubary F, Nguyen H, Nguyen TA, Khormaee S, Jain S, Hawkins K, Kumar S, Rolland JP, Beattie PD, Chau NV, Quang VM, Barfield C, Tietje K, Steele M, Weigl BH
Field evaluation of a prototype paper-based point-of-care fingerstick transaminase test. PLoS One. 2013; 8(9):e75616.
Field evaluation of a prototype paper-based point-of-care fingerstick transaminase test.
Nira Pollock, Boston Children's Hospital
Christopher DJ, Schumacher SG, Michael JS, Luo R, Balamugesh T, Duraikannan P, Pollock NR, Pai M, Denkinger CM
Performance of Xpert MTB/RIF on pleural tissue for the diagnosis of pleural tuberculosis. Eur Respir J. 2013 Nov; 42(5):1427-9.
Performance of Xpert MTB/RIF on pleural tissue for the diagnosis of pleural tuberculosis.
Microfluidic chip for molecular amplification of influenza A RNA in human respiratory specimens. PLoS One. 2012; 7(3):e33176.
Microfluidic chip for molecular amplification of influenza A RNA in human respiratory specimens.
Salari A, Camacho Valenzuela JG, Le N, Dahmer J, Sklavounos AA, Kan CW, Manning R, Duffy DC, Pollock NR, Wheeler AR
A digital microfluidic approach to increasing sample volume and reducing bead numbers in single molecule array assays. Lab Chip. 2025 Mar 25; 25(7):1669-1680.
A digital microfluidic approach to increasing sample volume and reducing bead numbers in single molecule array assays.
Wang L, Chen X, Pollock NR, Villafuerte Gálvez JA, Alonso CD, Wang D, Daugherty K, Xu H, Yao J, Chen Y, Kelly CP, Cao Y
Metagenomic analysis reveals distinct patterns of gut microbiota features with diversified functions in C. difficile infection (CDI), asymptomatic carriage and non-CDI diarrhea. Gut Microbes. 2025 Dec; 17(1):2505269.
Metagenomic analysis reveals distinct patterns of gut microbiota features with diversified functions in C. difficile infection (CDI), asymptomatic carriage and non-CDI diarrhea.
Bassit L, Damhorst GL, Bowers HB, Sabino C, Sullivan J, Kennedy EB, Khouri J, Miller P, Lai E, Schinazi RF, Lam W, Pollock NR, Rao A
Towards diagnostic preparedness: detection of highly pathogenic avian influenza A(H5N1) in contrived nasal swab specimens using rapid antigen and point-of-care molecular tests. medRxiv. 2025 Apr 16.
Towards diagnostic preparedness: detection of highly pathogenic avian influenza A(H5N1) in contrived nasal swab specimens using rapid antigen and point-of-care molecular tests.
Le NH, Sathishkumar N, Salari A, Manning R, Meyer RE, Kan CW, Wiener AD, Rossotti MA, Decombe S, de Campos RPS, Chamberlain MD, Tanha J, Pollock NR, Duffy DC, Wheeler AR
A compartmentalization-free microfluidic digital assay for detecting picogram levels of protein analytes. Lab Chip. 2025 Jun 10; 25(12):2862-2873.
A compartmentalization-free microfluidic digital assay for detecting picogram levels of protein analytes.
Sandora TJ, Savage TJ, Ryan ME, Dahlberg SE, Daugherty K, Kelly CP, Pollock NR, Kociolek LK
Antimicrobial stewardship & healthcare epidemiology : ASHE
Comparative effectiveness of metronidazole and vancomycin for treatment of Clostridioides difficile infection in hospitalized children. Antimicrob Steward Healthc Epidemiol. 2025; 5(1):e74.
Comparative effectiveness of metronidazole and vancomycin for treatment of Clostridioides difficile infection in hospitalized children.
Denkinger CM, Kalantri Y, Schumacher SG, Michael JS, Shankar D, Saxena A, Sriram N, Balamugesh T, Luo R, Pollock NR, Pai M, Christopher DJ
Challenges in the development of an immunochromatographic interferon-gamma test for diagnosis of pleural tuberculosis. PLoS One. 2013; 8(12):e85447.
Challenges in the development of an immunochromatographic interferon-gamma test for diagnosis of pleural tuberculosis.
Pollock NR, McAdam AJ, Pai M, Nardell EA, Bernardo J, Banaei N, Mobo J
Interferon ?-release assays for diagnosis of latent tuberculosis in healthcare workers in low-incidence settings: pros and cons. Clin Chem. 2014 May; 60(5):714-8.
Interferon ?-release assays for diagnosis of latent tuberculosis in healthcare workers in low-incidence settings: pros and cons.
Denkinger CM, Cunningham J, Faehling V, Brümmer LE, Hanson K, Molenkamp R, Miller MB, Marcato AJ, Price DJ, Ciesek S, Agogo E, Fitchett J, Ströher U, Yadav PD, Bergeri I, Boddington NL, Pollock NR
Bulletin of the World Health Organization
Diagnosis of the first few cases of a novel respiratory pathogen: the FFX-Dx protocol. Bull World Health Organ. 2026 Feb 01; 104(2):118-120.
Diagnosis of the first few cases of a novel respiratory pathogen: the FFX-Dx protocol.
Hunt JH, Damhorst GL, Parsons R, Frediani JK, McLendon KB, Sullivan J, Westbrook AL, Lam WA, Martin GS, Pollock NR
Peak Nasal SARS-CoV-2 and Influenza Viral Loads Relative to Symptom Onset, 2022-2025: Impact of Vaccination and Implications for Multiplexed Testing. medRxiv. 2025 Dec 30.
Peak Nasal SARS-CoV-2 and Influenza Viral Loads Relative to Symptom Onset, 2022-2025: Impact of Vaccination and Implications for Multiplexed Testing.
Bassit L, Damhorst GL, Bowers HB, Sabino C, Sullivan J, Kennedy EB, Khouri J, Miller P, Lai E, Schinazi RF, Lam WA, Pollock NR, Rao A
Toward diagnostic preparedness: detection of highly pathogenic avian influenza A(H5N1) in contrived nasal swab specimens using rapid antigen and point-of-care molecular tests. J Clin Microbiol. 2025 Sep 10; 63(9):e0054825.
Toward diagnostic preparedness: detection of highly pathogenic avian influenza A(H5N1) in contrived nasal swab specimens using rapid antigen and point-of-care molecular tests.
Pollock NR, Song L, Zhao M, Duffy DC, Chen X, Sambol SP, Gerding DN, Kelly CP
Differential immunodetection of toxin B from highly virulent Clostridium difficile BI/NAP-1/027. J Clin Microbiol. 2015 May; 53(5):1705-8.
Differential immunodetection of toxin B from highly virulent Clostridium difficile BI/NAP-1/027.
Jain S, Rajasingham R, Noubary F, Coonahan E, Schoeplein R, Baden R, Curry M, Afdhal N, Kumar S, Pollock NR
Performance of an Optimized Paper-Based Test for Rapid Visual Measurement of Alanine Aminotransferase (ALT) in Fingerstick and Venipuncture Samples. PLoS One. 2015; 10(5):e0128118.
Performance of an Optimized Paper-Based Test for Rapid Visual Measurement of Alanine Aminotransferase (ALT) in Fingerstick and Venipuncture Samples.
Song L, Zhao M, Duffy DC, Hansen J, Shields K, Wungjiranirun M, Chen X, Xu H, Leffler DA, Sambol SP, Gerding DN, Kelly CP, Pollock NR
Development and Validation of Digital Enzyme-Linked Immunosorbent Assays for Ultrasensitive Detection and Quantification of Clostridium difficile Toxins in Stool. J Clin Microbiol. 2015 Oct; 53(10):3204-12.
Development and Validation of Digital Enzyme-Linked Immunosorbent Assays for Ultrasensitive Detection and Quantification of Clostridium difficile Toxins in Stool.
Rodriguez NM, Linnes JC, Fan A, Ellenson CK, Pollock NR, Klapperich CM
Paper-Based RNA Extraction, in Situ Isothermal Amplification, and Lateral Flow Detection for Low-Cost, Rapid Diagnosis of Influenza A (H1N1) from Clinical Specimens. Anal Chem. 2015 Aug 04; 87(15):7872-9.
Paper-Based RNA Extraction, in Situ Isothermal Amplification, and Lateral Flow Detection for Low-Cost, Rapid Diagnosis of Influenza A (H1N1) from Clinical Specimens.
Broadhurst MJ, Kelly JD, Miller A, Semper A, Bailey D, Groppelli E, Simpson A, Brooks T, Hula S, Nyoni W, Sankoh AB, Kanu S, Jalloh A, Ton Q, Sarchet N, George P, Perkins MD, Wonderly B, Murray M, Pollock NR
ReEBOV Antigen Rapid Test kit for point-of-care and laboratory-based testing for Ebola virus disease: a field validation study. Lancet. 2015 Aug 29; 386(9996):867-74.
ReEBOV Antigen Rapid Test kit for point-of-care and laboratory-based testing for Ebola virus disease: a field validation study.
Lipsett SC, Pollock NR, Branda JA, Gordon CD, Gordon CR, Lantos PM, Nigrovic LE
The Positive Predictive Value of Lyme Elisa for the Diagnosis of Lyme Disease in Children. Pediatr Infect Dis J. 2015 Nov; 34(11):1260-2.
The Positive Predictive Value of Lyme Elisa for the Diagnosis of Lyme Disease in Children.
Zhang JY, Mahalanabis M, Liu L, Chang J, Pollock NR, Klapperich CM
A Disposable Microfluidic Virus Concentration Device Based on Evaporation and Interfacial Tension. Diagnostics (Basel). 2013 Mar; 3(1):155-169.
A Disposable Microfluidic Virus Concentration Device Based on Evaporation and Interfacial Tension.
Ultrasensitive Detection and Quantification of Toxins for Optimized Diagnosis of Clostridium difficile Infection. J Clin Microbiol. 2016 Feb; 54(2):259-64.
Ultrasensitive Detection and Quantification of Toxins for Optimized Diagnosis of Clostridium difficile Infection.
Semper AE, Broadhurst MJ, Richards J, Foster GM, Simpson AJ, Logue CH, Kelly JD, Miller A, Brooks TJ, Murray M, Pollock NR
Performance of the GeneXpert Ebola Assay for Diagnosis of Ebola Virus Disease in Sierra Leone: A Field Evaluation Study. PLoS Med. 2016 Mar; 13(3):e1001980.
Performance of the GeneXpert Ebola Assay for Diagnosis of Ebola Virus Disease in Sierra Leone: A Field Evaluation Study.
Broadhurst MJ, Semper A, Bailey D, Pollock NR
ReEBOV Antigen Rapid Test kit for Ebola - Authors' reply. Lancet. 2015 Dec 05; 386(10010):2255-6.
ReEBOV Antigen Rapid Test kit for Ebola - Authors' reply.
Diagnosis of Ebola Virus Disease: Past, Present, and Future. Clin Microbiol Rev. 2016 Oct; 29(4):773-93.
Diagnosis of Ebola Virus Disease: Past, Present, and Future.
Semper A, Broadhurst MJ, Richards J, Foster GM, Simpson A, Groppelli E, Johnson J, Kelly JD, Brooks T, Logue CH, Miller A, Murray M, Pollock NR
Field Laboratory Evaluation of the GeneXpert Ebola Assay for Diagnosis of Ebola Virus Disease in Sierra Leone. Open Forum Infect Dis. 2015 Dec; 2(Suppl 1).
Field Laboratory Evaluation of the GeneXpert Ebola Assay for Diagnosis of Ebola Virus Disease in Sierra Leone.
Mehrotra P, Quinonez LG, Surana NK, Pollock N, Sandora TJ
Clinical Utility of Preimplantation Homograft Cultures in Patients Undergoing Congenital Cardiac Surgery. J Pediatric Infect Dis Soc. 2017 Jun 01; 6(2):202-204.
Clinical Utility of Preimplantation Homograft Cultures in Patients Undergoing Congenital Cardiac Surgery.
Alawdah LS, Campbell JN, Pollock N, Watnick PI
Erysipelothrix rhusiopathiae Suppurative Arthritis in a 12-year-old Boy After an Unusual Fresh Water Exposure. Pediatr Infect Dis J. 2017 04; 36(4):431-433.
Erysipelothrix rhusiopathiae Suppurative Arthritis in a 12-year-old Boy After an Unusual Fresh Water Exposure.
Evaluating Novel Diagnostics in an Outbreak Setting: Lessons Learned from Ebola. J Clin Microbiol. 2017 05; 55(5):1255-1261.
Evaluating Novel Diagnostics in an Outbreak Setting: Lessons Learned from Ebola.
Pollock NR, Kashino SS, Napolitano DR, Sloutsky A, Joshi S, Guillet J, Wong M, Nardell E, Campos-Neto A
Evaluation of the effect of treatment of latent tuberculosis infection on QuantiFERON-TB gold assay results. Infect Control Hosp Epidemiol. 2009 Apr; 30(4):392-5.
Evaluation of the effect of treatment of latent tuberculosis infection on QuantiFERON-TB gold assay results.
Sauer-Budge AF, Brookfield SJ, Janzen R, McGray S, Boardman A, Wirz H, Pollock NR
A novel device for collecting and dispensing fingerstick blood for point of care testing. PLoS One. 2017; 12(8):e0183625.
A novel device for collecting and dispensing fingerstick blood for point of care testing.
Pollock, Nira, M.D., Ph.D.; Kashino, Suely, Ph.D.; Campos-Neto, Antonio, M.D., Ph.D.
43rd Joint Tuberculosis/Leprosy Conference and Diagnostics Workshop
Development of a Novel Urine Antigen Detection Test for Active Tuberculosis. 43rd Joint Tuberculosis/Leprosy Conference and Diagnostics Workshop . 2008.
Development of a Novel Urine Antigen Detection Test for Active Tuberculosis
Kashino SS, Pollock N, Napolitano DR, Rodrigues V, Campos-Neto A
Identification and characterization of Mycobacterium tuberculosis antigens in urine of patients with active pulmonary tuberculosis: an innovative and alternative approach of antigen discovery of useful microbial molecules. Clin Exp Immunol. 2008 Jul; 153(1):56-62.
Identification and characterization of Mycobacterium tuberculosis antigens in urine of patients with active pulmonary tuberculosis: an innovative and alternative approach of antigen discovery of useful microbial molecules.
Pollock NR, Campos-Neto A, Kashino S, Napolitano D, Behar SM, Shin D, Sloutsky A, Joshi S, Guillet J, Wong M, Nardell E
Discordant QuantiFERON-TB Gold test results among US healthcare workers with increased risk of latent tuberculosis infection: a problem or solution? Infect Control Hosp Epidemiol. 2008 Sep; 29(9):878-86.
Discordant QuantiFERON-TB Gold test results among US healthcare workers with increased risk of latent tuberculosis infection: a problem or solution?
Pollock NR, Rolland JP, Kumar S, Beattie PD, Jain S, Noubary F, Wong VL, Pohlmann RA, Ryan US, Whitesides GM
A paper-based multiplexed transaminase test for low-cost, point-of-care liver function testing. Sci Transl Med. 2012 Sep 19; 4(152):152ra129.
A paper-based multiplexed transaminase test for low-cost, point-of-care liver function testing.
Pollock NR, Duong S, Cheng A, Han LL, Smole S, Kirby JE
Ruling out novel H1N1 influenza virus infection with direct fluorescent antigen testing. Clin Infect Dis. 2009 Sep 15; 49(6):e66-8.
Ruling out novel H1N1 influenza virus infection with direct fluorescent antigen testing.
Assessing the Burden of Clostridium difficile Infection in Low- and Middle-Income Countries. J Clin Microbiol. 2018 03; 56(3).
Assessing the Burden of Clostridium difficile Infection in Low- and Middle-Income Countries.
Pollock N, Dhiman R, Daifalla N, Farhat M, Campos-Neto A
Discovery of a unique Mycobacterium tuberculosis protein through proteomic analysis of urine from patients with active tuberculosis. Microbes Infect. 2018 04; 20(4):228-235.
Discovery of a unique Mycobacterium tuberculosis protein through proteomic analysis of urine from patients with active tuberculosis.
Napolitano DR, Pollock N, Kashino SS, Rodrigues V, Campos-Neto A
Identification of Mycobacterium tuberculosis ornithine carboamyltransferase in urine as a possible molecular marker of active pulmonary tuberculosis. Clin Vaccine Immunol. 2008 Apr; 15(4):638-43.
Identification of Mycobacterium tuberculosis ornithine carboamyltransferase in urine as a possible molecular marker of active pulmonary tuberculosis.
Pollock N, Koonce MP, de Hostos EL, Vale RD
In vitro microtubule-based organelle transport in wild-type Dictyostelium and cells overexpressing a truncated dynein heavy chain. Cell Motil Cytoskeleton. 1998; 40(3):304-14.
In vitro microtubule-based organelle transport in wild-type Dictyostelium and cells overexpressing a truncated dynein heavy chain.
University of California San Francisco, Biochemistry
Harvard Medical School/MIT, Clinical Research
Beth Israel Deaconess Medical Center, Medical Microbiology
Brigham and Women's Hospital, Internal Medicine
Beth Israel Deaconess Medical Center, Infectious Diseases
Harvard/MIT, Clinical Investigator Training Program
Beth Israel Deaconess Medical Center, CPEP Medical Microbiology Fellowship