Corresponding Member of the Faculty of Pediatrics
Comeau AM, Parad R, Gerstle R, O'Sullivan BP, Dorkin HL, Dovey M, Haver K, Martin T, Eaton RB
Challenges in implementing a successful newborn cystic fibrosis screening program. J Pediatr. 2005 Sep; 147(3 Suppl):S89-93.
Challenges in implementing a successful newborn cystic fibrosis screening program.
Ramsey BW, Astley SJ, Aitken ML, Burke W, Colin AA, Dorkin HL, Eisenberg JD, Gibson RL, Harwood IR, Schidlow DV
The American review of respiratory disease
Efficacy and safety of short-term administration of aerosolized recombinant human deoxyribonuclease in patients with cystic fibrosis. Am Rev Respir Dis. 1993 Jul; 148(1):145-51.
Efficacy and safety of short-term administration of aerosolized recombinant human deoxyribonuclease in patients with cystic fibrosis.
Lutchen KR, Habib RH, Dorkin HL, Wall MA
Journal of applied physiology (Bethesda, Md. : 1985)
Respiratory impedance and multibreath N2 washout in healthy, asthmatic, and cystic fibrosis subjects. J Appl Physiol (1985). 1990 May; 68(5):2139-49.
Respiratory impedance and multibreath N2 washout in healthy, asthmatic, and cystic fibrosis subjects.
Moss RB, Milla C, Colombo J, Accurso F, Zeitlin PL, Clancy JP, Spencer LT, Pilewski J, Waltz DA, Dorkin HL, Ferkol T, Pian M, Ramsey B, Carter BJ, Martin DB, Heald AE
Repeated aerosolized AAV-CFTR for treatment of cystic fibrosis: a randomized placebo-controlled phase 2B trial. Hum Gene Ther. 2007 Aug; 18(8):726-32.
Repeated aerosolized AAV-CFTR for treatment of cystic fibrosis: a randomized placebo-controlled phase 2B trial.
Parad RB, Comeau AM, Dorkin HL, Dovey M, Gerstle R, Martin T, O'Sullivan BP
Sweat testing infants detected by cystic fibrosis newborn screening. J Pediatr. 2005 Sep; 147(3 Suppl):S69-72.
Sweat testing infants detected by cystic fibrosis newborn screening.
Grubman SA, Fang SL, Mulberg AE, Perrone RD, Rogers LC, Lee DW, Armentano D, Murray SL, Dorkin HL, Cheng SH
Correction of the cystic fibrosis defect by gene complementation in human intrahepatic biliary epithelial cell lines. Gastroenterology. 1995 Feb; 108(2):584-92.
Correction of the cystic fibrosis defect by gene complementation in human intrahepatic biliary epithelial cell lines.
Inverse modeling of dog airway and respiratory system impedances. J Appl Physiol (1985). 1987 Jun; 62(6):2273-82.
Inverse modeling of dog airway and respiratory system impedances.
CT appearance of the liver in a patient with biliary cirrhosis and cystic fibrosis. J Comput Assist Tomogr. 1983 Jun; 7(3):530-3.
CT appearance of the liver in a patient with biliary cirrhosis and cystic fibrosis.
Yersinia enterocolitica septicemia. Am J Clin Pathol. 1978 Feb; 69(2):189-92.
Congenital pulmonary malformations in pediatric patients: review and update on etiology, classification, and imaging findings. Radiol Clin North Am. 2011 Sep; 49(5):921-48.
Congenital pulmonary malformations in pediatric patients: review and update on etiology, classification, and imaging findings.
Ramsey BW, Dorkin HL, Eisenberg JD, Gibson RL, Harwood IR, Kravitz RM, Schidlow DV, Wilmott RW, Astley SJ, McBurnie MA
Efficacy of aerosolized tobramycin in patients with cystic fibrosis. N Engl J Med. 1993 Jun 17; 328(24):1740-6.
Efficacy of aerosolized tobramycin in patients with cystic fibrosis.
Density dependence of respiratory system impedances between 5 and 320 Hz in humans. J Appl Physiol (1985). 1989 Dec; 67(6):2323-30.
Density dependence of respiratory system impedances between 5 and 320 Hz in humans.
Stone PJ, Konstan MW, Berger M, Dorkin HL, Franzblau C, Snider GL
American journal of respiratory and critical care medicine
Elastin and collagen degradation products in urine of patients with cystic fibrosis. Am J Respir Crit Care Med. 1995 Jul; 152(1):157-62.
Elastin and collagen degradation products in urine of patients with cystic fibrosis.
Dorkin HL, Stark AR, Werthammer JW, Strieder DJ, Fredberg JJ, Frantz ID
Respiratory system impedance from 4 to 40 Hz in paralyzed intubated infants with respiratory disease. J Clin Invest. 1983 Sep; 72(3):903-10.
Respiratory system impedance from 4 to 40 Hz in paralyzed intubated infants with respiratory disease.
Richards B, Skoletsky J, Shuber AP, Balfour R, Stern RC, Dorkin HL, Parad RB, Witt D, Klinger KW
Multiplex PCR amplification from the CFTR gene using DNA prepared from buccal brushes/swabs. Hum Mol Genet. 1993 Feb; 2(2):159-63.
Multiplex PCR amplification from the CFTR gene using DNA prepared from buccal brushes/swabs.
Dorkin HL, Jackson AC, Strieder DJ, Dawson SV
Journal of applied physiology: respiratory, environmental and exercise physiology
Interaction of oscillatory and unidirectional flows in straight tubes and an airway cast. J Appl Physiol Respir Environ Exerc Physiol. 1982 Apr; 52(4):1097-1105.
J Appl Physiol Respir Environ Exerc Physiol
Interaction of oscillatory and unidirectional flows in straight tubes and an airway cast.
Hale JE, Parad RB, Dorkin HL, Gerstle R, Lapey A, O'Sullivan BP, Spencer T, Yee W, Comeau AM
Cystic fibrosis newborn screening: using experience to optimize the screening algorithm. J Inherit Metab Dis. 2010 Oct; 33(Suppl 2):S255-61.
Cystic fibrosis newborn screening: using experience to optimize the screening algorithm.
Clancy JP, Rowe SM, Accurso FJ, Aitken ML, Amin RS, Ashlock MA, Ballmann M, Boyle MP, Bronsveld I, Campbell PW, De Boeck K, Donaldson SH, Dorkin HL, Dunitz JM, Durie PR, Jain M, Leonard A, McCoy KS, Moss RB, Pilewski JM, Rosenbluth DB, Rubenstein RC, Schechter MS, Botfield M, Ordoñez CL, Spencer-Green GT, Vernillet L, Wisseh S, Yen K, Konstan MW
Results of a phase IIa study of VX-809, an investigational CFTR corrector compound, in subjects with cystic fibrosis homozygous for the F508del-CFTR mutation. Thorax. 2012 Jan; 67(1):12-8.
Results of a phase IIa study of VX-809, an investigational CFTR corrector compound, in subjects with cystic fibrosis homozygous for the F508del-CFTR mutation.
Eisenberg JD, Aitken ML, Dorkin HL, Harwood IR, Ramsey BW, Schidlow DV, Wilmott RW, Wohl ME, Fuchs HJ, Christiansen DH, Smith AL
Safety of repeated intermittent courses of aerosolized recombinant human deoxyribonuclease in patients with cystic fibrosis. J Pediatr. 1997 Jul; 131(1 Pt 1):118-24.
Safety of repeated intermittent courses of aerosolized recombinant human deoxyribonuclease in patients with cystic fibrosis.
Miller K, Gouveia WA, Barza M, Bower K, Curtis L, Decker EL, Dorkin H, Estes M, Mackey W, Marchbein D
Undesirable marketing practices in the pharmaceutical industry. N Engl J Med. 1985 Jul 04; 313(1):54.
Undesirable marketing practices in the pharmaceutical industry.
Harris C, Katkin J, Cataletto M, Dorkin H, Laskosz L, Ruch-Ross H
US pediatric pulmonology workforce. Pediatr Pulmonol. 2019 04; 54(4):444-450.
Cystic Fibrosis Transmembrane Conductance Regulator
Associate Professor of Psychiatry, Part-time
Bartley BL, Schwartz CE, Stark RB, Georgiopoulos AM, Friedman D, Richards CJ, Dorkin HL, Kinane TB, Neuringer IP, Yonker LM
Lung transplant referral practice patterns: a survey of cystic fibrosis physicians and general pulmonologists. BMC Pulm Med. 2020 Mar 04; 20(1):58.
Lung transplant referral practice patterns: a survey of cystic fibrosis physicians and general pulmonologists.
West NE, Konstan MW, Flume PA, VanDevanter DR, Magaret A, Mazurek H, Amelina EL, Laki I, Chiron R, Sutharsan S, Columbo C, Dorkin HL, Downey DG, Sole A, Hjelte L, Tullis E, Dgetluck N, Dinh Q, Constantine S, White B, Elborn JS, Chmiel JF
Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society
Cannabinoid receptor 2 agonist, lenabasum, for the treatment of pulmonary exacerbations in cystic fibrosis. J Cyst Fibros. 2025 Jul; 24(4):691-697.
Cannabinoid receptor 2 agonist, lenabasum, for the treatment of pulmonary exacerbations in cystic fibrosis.
Hale JE, O'Sullivan BP, Parad RB, Dorkin HL, Kremer TM, Vehse NW, Yonker LM, Sawicki GS, Counihan AM, Gerstel-Thompson J, Kumar B, Comeau AM
Genetics in medicine : official journal of the American College of Medical Genetics
Expansion of variant panels in newborn screening algorithms to identify cystic fibrosis: A retrospective analysis of 25 years of genotypes and implications on diagnosis. Genet Med. 2026 Jan; 28(1):101629.
Expansion of variant panels in newborn screening algorithms to identify cystic fibrosis: A retrospective analysis of 25 years of genotypes and implications on diagnosis.
Dorkin HL, Staab D, Operschall E, Alder J, Criollo M
Ciprofloxacin DPI: a randomised, placebo-controlled, phase IIb efficacy and safety study on cystic fibrosis. BMJ Open Respir Res. 2015; 2(1):e000100.
Ciprofloxacin DPI: a randomised, placebo-controlled, phase IIb efficacy and safety study on cystic fibrosis.
Gaggar A, Chen J, Chmiel JF, Dorkin HL, Flume PA, Griffin R, Nichols D, Donaldson SH
Inhaled alpha1-proteinase inhibitor therapy in patients with cystic fibrosis. J Cyst Fibros. 2016 Mar; 15(2):227-33.
Inhaled alpha1-proteinase inhibitor therapy in patients with cystic fibrosis.
Jefferson DM, Valentich JD, Marini FC, Grubman SA, Iannuzzi MC, Dorkin HL, Li M, Klinger KW, Welsh MJ
Expression of normal and cystic fibrosis phenotypes by continuous airway epithelial cell lines. Am J Physiol. 1990 Dec; 259(6 Pt 1):L496-505.
Expression of normal and cystic fibrosis phenotypes by continuous airway epithelial cell lines.
Comeau AM, Parad RB, Dorkin HL, Dovey M, Gerstle R, Haver K, Lapey A, O'Sullivan BP, Waltz DA, Zwerdling RG, Eaton RB
Population-based newborn screening for genetic disorders when multiple mutation DNA testing is incorporated: a cystic fibrosis newborn screening model demonstrating increased sensitivity but more carrier detections. Pediatrics. 2004 Jun; 113(6):1573-81.
Population-based newborn screening for genetic disorders when multiple mutation DNA testing is incorporated: a cystic fibrosis newborn screening model demonstrating increased sensitivity but more carrier detections.
Fisher RA, Turner BM, Dorkin H, Harris H
Clinica chimica acta; international journal of clinical chemistry
An investigation of some factors affecting levels of erythrocyte inorganic pyrophosphatase activity. Clin Chim Acta. 1975 May 15; 61(1):27-37.
An investigation of some factors affecting levels of erythrocyte inorganic pyrophosphatase activity.
Meissner HC, Welliver RC, Chartrand SA, Law BJ, Weisman LE, Dorkin HL, Rodriguez WJ
The Pediatric infectious disease journal
Immunoprophylaxis with palivizumab, a humanized respiratory syncytial virus monoclonal antibody, for prevention of respiratory syncytial virus infection in high risk infants: a consensus opinion. Pediatr Infect Dis J. 1999 Mar; 18(3):223-31.
Immunoprophylaxis with palivizumab, a humanized respiratory syncytial virus monoclonal antibody, for prevention of respiratory syncytial virus infection in high risk infants: a consensus opinion.
Joseph PM, O'Sullivan BP, Lapey A, Dorkin H, Oren J, Balfour R, Perricone MA, Rosenberg M, Wadsworth SC, Smith AE, St George JA, Meeker DP
Aerosol and lobar administration of a recombinant adenovirus to individuals with cystic fibrosis. I. Methods, safety, and clinical implications. Hum Gene Ther. 2001 Jul 20; 12(11):1369-82.
Aerosol and lobar administration of a recombinant adenovirus to individuals with cystic fibrosis. I. Methods, safety, and clinical implications.
Redding GJ, Cloutier MM, Dorkin HL, Brotherton SE, Mulvey HJ
Practice of pediatric pulmonology: results of the Future of Pediatric Education Project (FOPE) Pediatr Pulmonol. 2000 Sep; 30(3):190-7.
Practice of pediatric pulmonology: results of the Future of Pediatric Education Project (FOPE)
Perricone MA, Morris JE, Pavelka K, Plog MS, O'Sullivan BP, Joseph PM, Dorkin H, Lapey A, Balfour R, Meeker DP, Smith AE, Wadsworth SC, St George JA
Aerosol and lobar administration of a recombinant adenovirus to individuals with cystic fibrosis. II. Transfection efficiency in airway epithelium. Hum Gene Ther. 2001 Jul 20; 12(11):1383-94.
Aerosol and lobar administration of a recombinant adenovirus to individuals with cystic fibrosis. II. Transfection efficiency in airway epithelium.
O'Sullivan BP, Zwerdling RG, Dorkin HL, Comeau AM, Parad R
Early pulmonary manifestation of cystic fibrosis in children with the DeltaF508/R117H-7T genotype. Pediatrics. 2006 Sep; 118(3):1260-5.
Early pulmonary manifestation of cystic fibrosis in children with the DeltaF508/R117H-7T genotype.
Human respiratory input impedance from 4 to 200 Hz: physiological and modeling considerations. J Appl Physiol (1985). 1988 Feb; 64(2):823-31.
Human respiratory input impedance from 4 to 200 Hz: physiological and modeling considerations.
Communications systems and their models: Massachusetts parent compliance with recommended specialty care after positive cystic fibrosis newborn screening result. J Pediatr. 2005 Sep; 147(3 Suppl):S98-100.
Communications systems and their models: Massachusetts parent compliance with recommended specialty care after positive cystic fibrosis newborn screening result.
Consensus conference: practical applications of Pulmozyme. September 22, 1993. Pediatr Pulmonol. 1994 Jun; 17(6):404-8.
Consensus conference: practical applications of Pulmozyme. September 22, 1993.
Fredberg JJ, Wohl ME, Glass GM, Dorkin HL
Airway area by acoustic reflections measured at the mouth. J Appl Physiol Respir Environ Exerc Physiol. 1980 May; 48(5):749-58.
Airway area by acoustic reflections measured at the mouth.
Fisher RA, Turner BM, Dorkin HL, Harris H
Studies on human erythrocyte inorganic pyrophosphatase. Ann Hum Genet. 1974 Jan; 37(3):341-53.
Studies on human erythrocyte inorganic pyrophosphatase.
Siggers DC, Rogers JG, Boyer SH, Margolet L, Dorkin H, Banerjee SP, Shooter EM
Increased nerve-growth-factor beta-chain cross-reacting material in familial dysautonomia. N Engl J Med. 1976 Sep 16; 295(12):629-34.
Increased nerve-growth-factor beta-chain cross-reacting material in familial dysautonomia.
Wheeler PG, Smith R, Dorkin H, Parad RB, Comeau AM, Bianchi DW
Genetic counseling after implementation of statewide cystic fibrosis newborn screening: Two years' experience in one medical center. Genet Med. 2001 Nov-Dec; 3(6):411-5.
Genetic counseling after implementation of statewide cystic fibrosis newborn screening: Two years' experience in one medical center.
Shnayderman M, Mansfield B, Yip P, Clark HA, Krebs MD, Cohen SJ, Zeskind JE, Ryan ET, Dorkin HL, Callahan MV, Stair TO, Gelfand JA, Gill CJ, Hitt B, Davis CE
Species-specific bacteria identification using differential mobility spectrometry and bioinformatics pattern recognition. Anal Chem. 2005 Sep 15; 77(18):5930-7.
Species-specific bacteria identification using differential mobility spectrometry and bioinformatics pattern recognition.
Jackson AC, Neff KM, Dorkin HL, Lutchen KR
Interpretation of respiratory input impedance in healthy infants. Pediatr Pulmonol. 1996 Dec; 22(6):364-75.
Interpretation of respiratory input impedance in healthy infants.