MF10MatthewFroschMatthew P. Frosch, M.D.,Ph.D.42.36241700000000-71.0689370000000069351Frosch, MatthewP.617/726-5156Professor of Pathologycatalyst:eCommonsLogineCommons Loginprns:coAuthorOfcoauthor ofprns:endDateend dateFaculty Rankprns:fullNamefull nameprns:hasAuthorListauthor listprns:hasFacultyRankhas faculty rankprns:hasNetworkhas networkprns:hasPublicationVenuepublished inprns:informationResourceReferenceinformation resource referenceprns:isPrimaryPositionis primary positionprns:latitudelatitudeprns:longitudelongitudeprns:mainImagephotoprns:maxWeightmaximum weightprns:medlineTAjournal title abbreviationprns:meshDescriptorUIMeSH DescriptorUIprns:meshSemanticGroupNameMeSH semantic group nameprns:minWeightminimum weightprns:numberOfAuthorsnumber of authorsprns:numberOfConnectionsnumber of connectionsprns:numberOfPublicationsnumber of publicationsprns:personIdPerson IDprns:personInPrimaryPositionperson in primary positionprns:physicalNeighborOfphysical neighborprns:positionInDepartmentposition in departmentprns:positionInDivisionposition in divisionprns:predicateNodepredicate nodeprns:principalInvestigatorNameprincipal investigator nameprns:publicationDatepublication dateprns:similarTosimilar toprns:sortOrdersort orderprns:startDatestart dateprns:uniquenessWeightuniqueness weightprns:yearyearAcademic ArticleArticleDocumentbibo:pmidPubMed IdentifierAddressvivo:address1address line 1vivo:address2address line 2vivo:address3address line 3vivo:addressCitycityvivo:addressPostalCodepostal codevivo:addressStatestate or provincevivo:authorInAuthorshipselected publicationsvivo:authorRankauthor rank in publicationAuthorshipDepartmentDivisionGrantvivo:hasResearchArearesearch areasvivo:hasResearcherRoleresearch activitiesvivo:hrJobTitleHR job titleInformation Resourcevivo:linkedAuthorlinked authorvivo:linkedInformationResourcelinked information resourcevivo:mailingAddressmailing addressvivo:middleNamemiddle name or initialvivo:personInPositionpositionsvivo:phoneNumberphonePositionvivo:positionInOrganizationposition in organizationvivo:preferredTitlepreferred titleResearcher Rolevivo:researcherRoleOfresearcher role ofvivo:roleContributesTocontributes tovivo:sponsorAwardIdsponsor award idrdf:predicatepredicaterdf:typetyperdfs:labellabelConceptAgentfoaf:firstNamefirst namefoaf:lastNamelast nameOrganizationPerson1632466Yamaguchi H, Yamazaki T, Lemere CA, Frosch MP, Selkoe DJThe American journal of pathologyBeta amyloid is focally deposited within the outer basement membrane in the amyloid angiopathy of Alzheimer's disease. An immunoelectron microscopic study. Am J Pathol. 1992 Jul; 141(1):249-59.Am J Pathol1992-07-01T00:00:001992Beta amyloid is focally deposited within the outer basement membrane in the amyloid angiopathy of Alzheimer's disease. An immunoelectron microscopic study.Authorship 103649415473963Hutter-Paier B, Huttunen HJ, Puglielli L, Eckman CB, Kim DY, Hofmeister A, Moir RD, Domnitz SB, Frosch MP, Windisch M, Kovacs DMNeuronThe ACAT inhibitor CP-113,818 markedly reduces amyloid pathology in a mouse model of Alzheimer's disease. Neuron. 2004 Oct 14; 44(2):227-38.Neuron2004-10-14T00:00:002004The ACAT inhibitor CP-113,818 markedly reduces amyloid pathology in a mouse model of Alzheimer's disease.19018241Freeman SH, Kandel R, Cruz L, Rozkalne A, Newell K, Frosch MP, Hedley-Whyte ET, Locascio JJ, Lipsitz LA, Hyman BTJournal of neuropathology and experimental neurologyPreservation of neuronal number despite age-related cortical brain atrophy in elderly subjects without Alzheimer disease. J Neuropathol Exp Neurol. 2008 Dec; 67(12):1205-12.J Neuropathol Exp Neurol2008-12-01T00:00:002008Preservation of neuronal number despite age-related cortical brain atrophy in elderly subjects without Alzheimer disease.Authorship 1041353Authorship 1056299829614677Lee CM, Jacobs HIL, Marquié M, Becker JA, Andrea NV, Jin DS, Schultz AP, Frosch MP, Gómez-Isla T, Sperling RA, Johnson KAJournal of Alzheimer's disease : JAD18F-Flortaucipir Binding in Choroid Plexus: Related to Race and Hippocampus Signal. J Alzheimers Dis. 2018; 62(4):1691-1702.J Alzheimers Dis2018-01-01T00:00:00201818F-Flortaucipir Binding in Choroid Plexus: Related to Race and Hippocampus Signal.12870204Kurzai O, Keith P, de Hoog S, Abele-Horn M, Frosch MMycosesPostmortem isolation of Pseudotaeniolina globosa from a patient with aortic aneurysm. Mycoses. 2003 Apr; 46(3-4):141-4.Mycoses2003-04-01T00:00:002003Postmortem isolation of Pseudotaeniolina globosa from a patient with aortic aneurysm.Authorship 103060620975516Skoglund L, Matsui T, Freeman SH, Wallin A, Blom ES, Frosch MP, Growdon JH, Hyman BT, Lannfelt L, Ingelsson M, Glaser AAlzheimer disease and associated disordersNovel progranulin mutation detected in 2 patients with FTLD. Alzheimer Dis Assoc Disord. 2011 Apr-Jun; 25(2):173-8.Alzheimer Dis Assoc Disord2011-04-01T00:00:002011Novel progranulin mutation detected in 2 patients with FTLD.Authorship 10577903329674595Filbin MG, Tirosh I, Hovestadt V, Shaw ML, Escalante LE, Mathewson ND, Neftel C, Frank N, Pelton K, Hebert CM, Haberler C, Yizhak K, Gojo J, Egervari K, Mount C, van Galen P, Bonal DM, Nguyen QD, Beck A, Sinai C, Czech T, Dorfer C, Goumnerova L, Lavarino C, Carcaboso AM, Mora J, Mylvaganam R, Luo CC, Peyrl A, Popovic M, Azizi A, Batchelor TT, Frosch MP, Martinez-Lage M, Kieran MW, Bandopadhayay P, Beroukhim R, Fritsch G, Getz G, Rozenblatt-Rosen O, Wucherpfennig KW, Louis DN, Monje M, Slavc I, Ligon KL, Golub TR, Regev A, Bernstein BE, Suvà MLScience (New York, N.Y.)Developmental and oncogenic programs in H3K27M gliomas dissected by single-cell RNA-seq. Science. 2018 04 20; 360(6386):331-335.Science2018-04-20T00:00:002018Developmental and oncogenic programs in H3K27M gliomas dissected by single-cell RNA-seq.Authorship 1060597829687257Hong W, Wang Z, Liu W, O'Malley TT, Jin M, Willem M, Haass C, Frosch MP, Walsh DMActa neuropathologicaDiffusible, highly bioactive oligomers represent a critical minority of soluble Aß in Alzheimer's disease brain. Acta Neuropathol. 2018 07; 136(1):19-40.Acta Neuropathol2018-04-23T00:00:002018Diffusible, highly bioactive oligomers represent a critical minority of soluble Aß in Alzheimer's disease brain.22160360Augustinack JC, Huber KE, Postelnicu GM, Kakunoori S, Wang R, van der Kouwe AJ, Wald LL, Stein TD, Frosch MP, Fischl BActa neuropathologicaEntorhinal verrucae geometry is coincident and correlates with Alzheimer's lesions: a combined neuropathology and high-resolution ex vivo MRI analysis. Acta Neuropathol. 2012 Jan; 123(1):85-96.Acta Neuropathol2011-12-13T00:00:002011Entorhinal verrucae geometry is coincident and correlates with Alzheimer's lesions: a combined neuropathology and high-resolution ex vivo MRI analysis.29733334DeVos SL, Corjuc BT, Commins C, Dujardin S, Bannon RN, Corjuc D, Moore BD, Bennett RE, Jorfi M, Gonzales JA, Dooley PM, Roe AD, Pitstick R, Irimia D, Frosch MP, Carlson GA, Hyman BTBrain : a journal of neurologyTau reduction in the presence of amyloid-ß prevents tau pathology and neuronal death in vivo. Brain. 2018 07 01; 141(7):2194-2212.Brain2018-07-01T00:00:002018Tau reduction in the presence of amyloid-ß prevents tau pathology and neuronal death in vivo.16482476Klucken J, Ingelsson M, Shin Y, Irizarry MC, Hedley-Whyte ET, Frosch M, Growdon J, McLean P, Hyman BTActa neuropathologicaClinical and biochemical correlates of insoluble alpha-synuclein in dementia with Lewy bodies. Acta Neuropathol. 2006 Feb; 111(2):101-8.Acta Neuropathol2006-02-16T00:00:002006Clinical and biochemical correlates of insoluble alpha-synuclein in dementia with Lewy bodies.16772874Matsui T, Ramasamy K, Ingelsson M, Fukumoto H, Conrad C, Frosch MP, Irizarry MC, Yuan J, Hyman BTJournal of neuropathology and experimental neurologyCoordinated expression of caspase 8, 3 and 7 mRNA in temporal cortex of Alzheimer disease: relationship to formic acid extractable abeta42 levels. J Neuropathol Exp Neurol. 2006 May; 65(5):508-15.J Neuropathol Exp Neurol2006-05-01T00:00:002006Coordinated expression of caspase 8, 3 and 7 mRNA in temporal cortex of Alzheimer disease: relationship to formic acid extractable abeta42 levels.16802167Ingelsson M, Ramasamy K, Cantuti-Castelvetri I, Skoglund L, Matsui T, Orne J, Kowa H, Raju S, Vanderburg CR, Augustinack JC, de Silva R, Lees AJ, Lannfelt L, Growdon JH, Frosch MP, Standaert DG, Irizarry MC, Hyman BTActa neuropathologicaNo alteration in tau exon 10 alternative splicing in tangle-bearing neurons of the Alzheimer's disease brain. Acta Neuropathol. 2006 Oct; 112(4):439-49.Acta Neuropathol2006-06-27T00:00:002006No alteration in tau exon 10 alternative splicing in tangle-bearing neurons of the Alzheimer's disease brain.Authorship 106427115Authorship 10645576Authorship 10655661029746652Giantini Larsen A, Grannan BL, Lee CK, Koch MJ, Williams EA, Frosch MP, Cahill DPJournal of neuropathology and experimental neurologyMalignant Melanoma Metastatic to Oligodendroglioma: Case Report and Literature Review of Tumor-to-Tumor Metastasis to Gliomas. J Neuropathol Exp Neurol. 2018 07 01; 77(7):549-554.J Neuropathol Exp Neurol2018-07-01T00:00:002018Malignant Melanoma Metastatic to Oligodendroglioma: Case Report and Literature Review of Tumor-to-Tumor Metastasis to Gliomas.29740275DeVos SL, Corjuc BT, Oakley DH, Nobuhara CK, Bannon RN, Chase A, Commins C, Gonzalez JA, Dooley PM, Frosch MP, Hyman BTFrontiers in neuroscienceSynaptic Tau Seeding Precedes Tau Pathology in Human Alzheimer's Disease Brain. 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J Neuropathol Exp Neurol. 2010 Aug; 69(8):777-88.J Neuropathol Exp Neurol2010-08-01T00:00:002010The acyl-coenzyme A: cholesterol acyltransferase inhibitor CI-1011 reverses diffuse brain amyloid pathology in aged amyloid precursor protein transgenic mice.Authorship 1069381629846690Jones PS, Carroll KT, Koch M, DiCesare JAT, Reitz K, Frosch M, Barker FG, Cahill DP, Curry WTNeurosurgeryIsocitrate Dehydrogenase Mutations in Low-Grade Gliomas Correlate With Prolonged Overall Survival in Older Patients. Neurosurgery. 2019 02 01; 84(2):519-528.Neurosurgery2019-02-01T00:00:002019Isocitrate Dehydrogenase Mutations in Low-Grade Gliomas Correlate With Prolonged Overall Survival in Older Patients.21465323Chow FC, Edlow BL, Frosch MP, Copen WA, Greer DMNeurocritical careOutcome in patients with H1N1 influenza and cerebrovascular injury treated with extracorporeal membrane oxygenation. 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Arch Neurol. 2011 Apr; 68(4):488-97.Arch Neurol2011-04-01T00:00:002011Genetic and clinical features of progranulin-associated frontotemporal lobar degeneration.22882328Snuderl M, Wirth D, Sheth SA, Bourne SK, Kwon CS, Ancukiewicz M, Curry WT, Frosch MP, Yaroslavsky ANBrain pathology (Zurich, Switzerland)Dye-enhanced multimodal confocal imaging as a novel approach to intraoperative diagnosis of brain tumors. Brain Pathol. 2013 Jan; 23(1):73-81.Brain Pathol2012-08-28T00:00:002012Dye-enhanced multimodal confocal imaging as a novel approach to intraoperative diagnosis of brain tumors.Authorship 104095510606357Youssef P, Roth J, Frosch M, Costello P, Fitzgerald O, Sorg C, Bresnihan BThe Journal of rheumatologyExpression of myeloid related proteins (MRP) 8 and 14 and the MRP8/14 heterodimer in rheumatoid arthritis synovial membrane. J Rheumatol. 1999 Dec; 26(12):2523-8.J Rheumatol1999-12-01T00:00:001999Expression of myeloid related proteins (MRP) 8 and 14 and the MRP8/14 heterodimer in rheumatoid arthritis synovial membrane.11431533Shimura H, Schlossmacher MG, Hattori N, Frosch MP, Trockenbacher A, Schneider R, Mizuno Y, Kosik KS, Selkoe DJScience (New York, N.Y.)Ubiquitination of a new form of alpha-synuclein by parkin from human brain: implications for Parkinson's disease. Science. 2001 Jul 13; 293(5528):263-9.Science2001-06-28T00:00:002001Ubiquitination of a new form of alpha-synuclein by parkin from human brain: implications for Parkinson's disease.23656989Serrano-Pozo A, Muzikansky A, Gómez-Isla T, Growdon JH, Betensky RA, Frosch MP, Hyman BTJournal of neuropathology and experimental neurologyDifferential relationships of reactive astrocytes and microglia to fibrillar amyloid deposits in Alzheimer disease. 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Brain. 2010 May; 133(Pt 5):1312-27.Brain2010-03-31T00:00:002010Beneficial effect of human anti-amyloid-beta active immunization on neurite morphology and tau pathology.Authorship 10740601129887088Butovsky O, Jedrychowski MP, Cialic R, Murugaiyan G, Wu PM, Doykan CE, Fanek Z, Greco DJ, Kiner O, Lawson RJ, Frosch MP, Pochet N, Krichevsky AM, Gygi SP, Berry J, Cudkowicz ME, Weiner HLInternational journal of developmental neuroscience : the official journal of the International Society for Developmental NeuroscienceREMOVED: Targeting miR-155 restores dysfunctional microglia and ameliorates disease in the SOD1 model of ALS. 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J Neurosci. 2012 Oct 24; 32(43):15181-92.J Neurosci2012-10-24T00:00:002012Apolipoprotein E, especially apolipoprotein E4, increases the oligomerization of amyloid ß peptide.23143602Whitcomb DC, LaRusch J, Krasinskas AM, Klei L, Smith JP, Brand RE, Neoptolemos JP, Lerch MM, Tector M, Sandhu BS, Guda NM, Orlichenko L, Alkaade S, Amann ST, Anderson MA, Baillie J, Banks PA, Conwell D, Coté GA, Cotton PB, DiSario J, Farrer LA, Forsmark CE, Johnstone M, Gardner TB, Gelrud A, Greenhalf W, Haines JL, Hartman DJ, Hawes RA, Lawrence C, Lewis M, Mayerle J, Mayeux R, Melhem NM, Money ME, Muniraj T, Papachristou GI, Pericak-Vance MA, Romagnuolo J, Schellenberg GD, Sherman S, Simon P, Singh VP, Slivka A, Stolz D, Sutton R, Weiss FU, Wilcox CM, Zarnescu NO, Wisniewski SR, O'Connell MR, Kienholz ML, Roeder K, Barmada MM, Yadav D, Devlin BNature geneticsCommon genetic variants in the CLDN2 and PRSS1-PRSS2 loci alter risk for alcohol-related and sporadic pancreatitis. Nat Genet. 2012 Dec; 44(12):1349-54.Nat Genet2012-11-11T00:00:002012Common genetic variants in the CLDN2 and PRSS1-PRSS2 loci alter risk for alcohol-related and sporadic pancreatitis.22120142Garcia-Alloza M, Gregory J, Kuchibhotla KV, Fine S, Wei Y, Ayata C, Frosch MP, Greenberg SM, Bacskai BJBrain : a journal of neurologyCerebrovascular lesions induce transient ß-amyloid deposition. Brain. 2011 Dec; 134(Pt 12):3697-707.Brain2011-11-26T00:00:002011Cerebrovascular lesions induce transient ß-amyloid deposition.15329430Schlossmacher MG, Hamann C, Cole AG, Gonzalez RG, Frosch MPThe New England journal of medicineCase records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 27-2004. A 79-year-old woman with disturbances in gait, cognition, and autonomic function. N Engl J Med. 2004 Aug 26; 351(9):912-22.N Engl J Med2004-08-26T00:00:002004Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 27-2004. 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Brain Pathol. 2009 Jan; 19(1):39-47.Brain Pathol2008-04-15T00:00:002008Adult onset leukodystrophy with neuroaxonal spheroids: clinical, neuroimaging and neuropathologic observations.18571777Eichler FS, Ren JQ, Cossoy M, Rietsch AM, Nagpal S, Moser AB, Frosch MP, Ransohoff RMAnnals of neurologyIs microglial apoptosis an early pathogenic change in cerebral X-linked adrenoleukodystrophy? Ann Neurol. 2008 Jun; 63(6):729-42.Ann Neurol2008-06-01T00:00:002008Is microglial apoptosis an early pathogenic change in cerebral X-linked adrenoleukodystrophy?19443797Greenberg SM, Nandigam RN, Delgado P, Betensky RA, Rosand J, Viswanathan A, Frosch MP, Smith EEStrokeMicrobleeds versus macrobleeds: evidence for distinct entities. Stroke. 2009 Jul; 40(7):2382-6.Stroke2009-05-14T00:00:002009Microbleeds versus macrobleeds: evidence for distinct entities.19457117Garcia-Alloza M, Prada C, Lattarulo C, Fine S, Borrelli LA, Betensky R, Greenberg SM, Frosch MP, Bacskai BJJournal of neurochemistryMatrix metalloproteinase inhibition reduces oxidative stress associated with cerebral amyloid angiopathy in vivo in transgenic mice. J Neurochem. 2009 Jun; 109(6):1636-47.J Neurochem2009-04-08T00:00:002009Matrix metalloproteinase inhibition reduces oxidative stress associated with cerebral amyloid angiopathy in vivo in transgenic mice.Authorship 1082647929992960Jin M, O'Nuallain B, Hong W, Boyd J, Lagomarsino VN, O'Malley TT, Liu W, Vanderburg CR, Frosch MP, Young-Pearse T, Selkoe DJ, Walsh DMNature communicationsAn in vitro paradigm to assess potential anti-Aß antibodies for Alzheimer's disease. 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Acta Neuropathol Commun. 2019 03 11; 7(1):37.Acta Neuropathol Commun2019-03-11T00:00:002019Autoradiography validation of novel tau PET tracer [F-18]-MK-6240 on human postmortem brain tissue.30820047Kunkle BW, Grenier-Boley B, Sims R, Bis JC, Damotte V, Naj AC, Boland A, Vronskaya M, van der Lee SJ, Amlie-Wolf A, Bellenguez C, Frizatti A, Chouraki V, Martin ER, Sleegers K, Badarinarayan N, Jakobsdottir J, Hamilton-Nelson KL, Moreno-Grau S, Olaso R, Raybould R, Chen Y, Kuzma AB, Hiltunen M, Morgan T, Ahmad S, Vardarajan BN, Epelbaum J, Hoffmann P, Boada M, Beecham GW, Garnier JG, Harold D, Fitzpatrick AL, Valladares O, Moutet ML, Gerrish A, Smith AV, Qu L, Bacq D, Denning N, Jian X, Zhao Y, Del Zompo M, Fox NC, Choi SH, Mateo I, Hughes JT, Adams HH, Malamon J, Sanchez-Garcia F, Patel Y, Brody JA, Dombroski BA, Naranjo MCD, Daniilidou M, Eiriksdottir G, Mukherjee S, Wallon D, Uphill J, Aspelund T, Cantwell LB, Garzia F, Galimberti D, Hofer E, Butkiewicz M, Fin B, Scarpini E, Sarnowski C, Bush WS, Meslage S, Kornhuber J, White CC, Song Y, Barber RC, Engelborghs S, Sordon S, Voijnovic D, Adams PM, Vandenberghe R, Mayhaus M, Cupples LA, Albert MS, De Deyn PP, Gu W, Himali JJ, Beekly D, Squassina A, Hartmann AM, Orellana A, Blacker D, Rodriguez-Rodriguez E, Lovestone S, Garcia ME, Doody RS, Munoz-Fernadez C, Sussams R, Lin H, Fairchild TJ, Benito YA, Holmes C, Karamujic-Comic H, Frosch MP, Thonberg H, Maier W, Roshchupkin G, Ghetti B, Giedraitis V, Kawalia A, Li S, Huebinger RM, Kilander L, Moebus S, Hernández I, Kamboh MI, Brundin R, Turton J, Yang Q, Katz MJ, Concari L, Lord J, Beiser AS, Keene CD, Helisalmi S, Kloszewska I, Kukull WA, Koivisto AM, Lynch A, Tarraga L, Larson EB, Haapasalo A, Lawlor B, Mosley TH, Lipton RB, Solfrizzi V, Gill M, Longstreth WT, Montine TJ, Frisardi V, Diez-Fairen M, Rivadeneira F, Petersen RC, Deramecourt V, Alvarez I, Salani F, Ciaramella A, Boerwinkle E, Reiman EM, Fievet N, Rotter JI, Reisch JS, Hanon O, Cupidi C, Andre Uitterlinden AG, Royall DR, Dufouil C, Maletta RG, de Rojas I, Sano M, Brice A, Cecchetti R, George-Hyslop PS, Ritchie K, Tsolaki M, Tsuang DW, Dubois B, Craig D, Wu CK, Soininen H, Avramidou D, Albin RL, Fratiglioni L, Germanou A, Apostolova LG, Keller L, Koutroumani M, Arnold SE, Panza F, Gkatzima O, Asthana S, Hannequin D, Whitehead P, Atwood CS, Caffarra P, Hampel H, Quintela I, Carracedo Á, Lannfelt L, Rubinsztein DC, Barnes LL, Pasquier F, Frölich L, Barral S, McGuinness B, Beach TG, Johnston JA, Becker JT, Passmore P, Bigio EH, Schott JM, Bird TD, Warren JD, Boeve BF, Lupton MK, Bowen JD, Proitsi P, Boxer A, Powell JF, Burke JR, Kauwe JSK, Burns JM, Mancuso M, Buxbaum JD, Bonuccelli U, Cairns NJ, McQuillin A, Cao C, Livingston G, Carlson CS, Bass NJ, Carlsson CM, Hardy J, Carney RM, Bras J, Carrasquillo MM, Guerreiro R, Allen M, Chui HC, Fisher E, Masullo C, Crocco EA, DeCarli C, Bisceglio G, Dick M, Ma L, Duara R, Graff-Radford NR, Evans DA, Hodges A, Faber KM, Scherer M, Fallon KB, Riemenschneider M, Fardo DW, Heun R, Farlow MR, Kölsch H, Ferris S, Leber M, Foroud TM, Heuser I, Galasko DR, Giegling I, Gearing M, Hüll M, Geschwind DH, Gilbert JR, Morris J, Green RC, Mayo K, Growdon JH, Feulner T, Hamilton RL, Harrell LE, Drichel D, Honig LS, Cushion TD, Huentelman MJ, Hollingworth P, Hulette CM, Hyman BT, Marshall R, Jarvik GP, Meggy A, Abner E, Menzies GE, Jin LW, Leonenko G, Real LM, Jun GR, Baldwin CT, Grozeva D, Karydas A, Russo G, Kaye JA, Kim R, Jessen F, Kowall NW, Vellas B, Kramer JH, Vardy E, LaFerla FM, Jöckel KH, Lah JJ, Dichgans M, Leverenz JB, Mann D, Levey AI, Pickering-Brown S, Lieberman AP, Klopp N, Lunetta KL, Wichmann HE, Lyketsos CG, Morgan K, Marson DC, Brown K, Martiniuk F, Medway C, Mash DC, Nöthen MM, Masliah E, Hooper NM, McCormick WC, Daniele A, McCurry SM, Bayer A, McDavid AN, Gallacher J, McKee AC, van den Bussche H, Mesulam M, Brayne C, Miller BL, Riedel-Heller S, Miller CA, Miller JW, Al-Chalabi A, Morris JC, Shaw CE, Myers AJ, Wiltfang J, O'Bryant S, Olichney JM, Alvarez V, Parisi JE, Singleton AB, Paulson HL, Collinge J, Perry WR, Mead S, Peskind E, Cribbs DH, Rossor M, Pierce A, Ryan NS, Poon WW, Nacmias B, Potter H, Sorbi S, et alNature geneticsGenetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates Aß, tau, immunity and lipid processing. Nat Genet. 2019 03; 51(3):414-430.Nat Genet2019-02-28T00:00:002019Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates Aß, tau, immunity and lipid processing.D024801Disorders1283060.73752TauopathiesD000544Disorders127179750.222139Alzheimer DiseaseD016657Disorders1048510.563173Cerebral Amyloid AngiopathyD016229Chemicals & Drugs59335790.387395Amyloid beta-PeptidesD016875Chemicals & Drugs43218610.48412tau ProteinsAuthorship 1149008931009358Schlunk F, Böhm M, Boulouis G, Qin T, Arbel M, Tamim I, Fischer P, Bacskai BJ, Frosch MP, Endres M, Greenberg SM, Ayata CStrokeSecondary Bleeding During Acute Experimental Intracerebral Hemorrhage. Stroke. 2019 05; 50(5):1210-1215.Stroke2019-05-01T00:00:002019Secondary Bleeding During Acute Experimental Intracerebral Hemorrhage.Authorship 1150125731032851Brinkmalm G, Hong W, Wang Z, Liu W, O'Malley TT, Sun X, Frosch MP, Selkoe DJ, Portelius E, Zetterberg H, Blennow K, Walsh DMBrain : a journal of neurologyIdentification of neurotoxic cross-linked amyloid-ß dimers in the Alzheimer's brain. Brain. 2019 05 01; 142(5):1441-1457.Brain2019-05-01T00:00:002019Identification of neurotoxic cross-linked amyloid-ß dimers in the Alzheimer's brain.NeurologyPathologyRadiologyBrigham and Women's HospitalMassachusetts General HospitalDJS1DennisSelkoeDennis J. Selkoe, M.D.42.33837200000000-71.1032690000000081795Selkoe, DennisVincent and Stella Coates Professor of Neurologic Diseases in the Department of NeurologyJCA2JeanAugustinackJean C. Augustinack, Ph.D.42.37730000000000-71.0525000000000069239Augustinack, JeanAssistant Professor of RadiologyELL1ElizabethLee-LewandrowskiElizabeth Lee-Lewandrowski, Ph.D.42.36241700000000-71.0689370000000082670Lee-Lewandrowski, ElizabethAssistant Professor of Pathology, Part-timeSMG5StevenGreenbergSteven Mark Greenberg, M.D.,Ph.D.42.36126580000000-71.0651591000000056448Greenberg, StevenProfessor of NeurologyMJF5MelindaLerwillMelinda Jean Fan Lerwill, M.D.42.36241700000000-71.0689370000000066463Lerwill, MelindaAssistant Professor of PathologyAuthorship 1156904731152566van Veluw SJ, Scherlek AA, Freeze WM, Ter Telgte A, van der Kouwe AJ, Bacskai BJ, Frosch MP, Greenberg SMAnnals of neurologyDifferent microvascular alterations underlie microbleeds and microinfarcts. Ann Neurol. 2019 08; 86(2):279-292.Ann Neurol2019-06-14T00:00:002019Different microvascular alterations underlie microbleeds and microinfarcts.RAS4ReisaSperlingReisa Anne Sperling, M.D.42.33710500000000-71.1023170000000020632Sperling, ReisaProfessor of NeurologyAuthorship 115837810Authorship 11585554Authorship 1158469331159702Pasi M, Pongpitakmetha T, Charidimou A, Singh SD, Tsai HH, Xiong L, Boulouis G, Warren AD, Rosand J, Frosch MP, Viswanathan A, Gurol ME, Greenberg SMStrokeCerebellar Microbleed Distribution Patterns and Cerebral Amyloid Angiopathy. Stroke. 2019 07; 50(7):1727-1733.Stroke2019-06-04T00:00:002019Cerebellar Microbleed Distribution Patterns and Cerebral Amyloid Angiopathy.8884739Vogel U, Hammerschmidt S, Frosch MMedical microbiology and immunologySialic acids of both the capsule and the sialylated lipooligosaccharide of Neisseria meningitis serogroup B are prerequisites for virulence of meningococci in the infant rat. Med Microbiol Immunol. 1996 Sep; 185(2):81-7.Med Microbiol Immunol1996-09-01T00:00:001996Sialic acids of both the capsule and the sialylated lipooligosaccharide of Neisseria meningitis serogroup B are prerequisites for virulence of meningococci in the infant rat.9403845Vogel U, Claus H, Heinze G, Frosch MMedical microbiology and immunologyFunctional characterization of an isogenic meningococcal alpha-2,3-sialyltransferase mutant: the role of lipooligosaccharide sialylation for serum resistance in serogroup B meningococci. Med Microbiol Immunol. 1997 Oct; 186(2-3):159-66.Med Microbiol Immunol1997-10-01T00:00:001997Functional characterization of an isogenic meningococcal alpha-2,3-sialyltransferase mutant: the role of lipooligosaccharide sialylation for serum resistance in serogroup B meningococci.BTH2BradleyHymanBradley Theodore Hyman, M.D., Ph.D.42.37904200000000-71.051481000000004393Hyman, BradleyJohn B. Penney, Jr. Professor of Neurology11409selected publications3.860690.003368531355research areas7.481450.00692753351coauthor of308.87927.049460similar toCW10Chin-LeeWuChin-Lee Wu, M.D., Ph.D.42.36241700000000-71.0689370000000029810Wu, Chin-LeeProfessor of PathologyKAJ1KeithJohnsonKeith Alan Johnson, M.D.42.36241700000000-71.0689370000000016670Johnson, KeithProfessor of RadiologyAuthorship 1165300831243072Shirvan J, Clement N, Ye R, Katz S, Schultz A, Johnson KA, Gomez-Isla T, Frosch M, Growdon JH, Gomperts SNNeurologyNeuropathologic correlates of amyloid and dopamine transporter imaging in Lewy body disease. 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JAMA Neurol. 2019 Oct 01; 76(10):1143-1144.JAMA Neurol2019-10-01T00:00:002019The Challenge of Defining Alzheimer Disease Based on Biomarkers in the Absence of Symptoms.Authorship 11758404331327527Neftel C, Laffy J, Filbin MG, Hara T, Shore ME, Rahme GJ, Richman AR, Silverbush D, Shaw ML, Hebert CM, Dewitt J, Gritsch S, Perez EM, Gonzalez Castro LN, Lan X, Druck N, Rodman C, Dionne D, Kaplan A, Bertalan MS, Small J, Pelton K, Becker S, Bonal D, Nguyen QD, Servis RL, Fung JM, Mylvaganam R, Mayr L, Gojo J, Haberler C, Geyeregger R, Czech T, Slavc I, Nahed BV, Curry WT, Carter BS, Wakimoto H, Brastianos PK, Batchelor TT, Stemmer-Rachamimov A, Martinez-Lage M, Frosch MP, Stamenkovic I, Riggi N, Rheinbay E, Monje M, Rozenblatt-Rosen O, Cahill DP, Patel AP, Hunter T, Verma IM, Ligon KL, Louis DN, Regev A, Bernstein BE, Tirosh I, Suvà MLCellAn Integrative Model of Cellular States, Plasticity, and Genetics for Glioblastoma. Cell. 2019 08 08; 178(4):835-849.e21.Cell2019-07-18T00:00:002019An Integrative Model of Cellular States, Plasticity, and Genetics for Glioblastoma.Authorship 1418594Authorship 1176646331359030Josephs KA, Mackenzie I, Frosch MP, Bigio EH, Neumann M, Arai T, Dugger BN, Ghetti B, Grossman M, Hasegawa M, Herrup K, Holton J, Jellinger K, Lashley T, McAleese KE, Parisi JE, Revesz T, Saito Y, Vonsattel JP, Whitwell JL, Wisniewski T, Hu WBrain : a journal of neurologyLATE to the PART-y. Brain. 2019 09 01; 142(9):e47.Brain2019-09-01T00:00:002019LATE to the PART-y.Authorship 11785999Authorship 1179075631395777Zott B, Simon MM, Hong W, Unger F, Chen-Engerer HJ, Frosch MP, Sakmann B, Walsh DM, Konnerth AScience (New York, N.Y.)A vicious cycle of ß amyloid-dependent neuronal hyperactivation. Science. 2019 08 09; 365(6453):559-565.Science2019-08-09T00:00:002019A vicious cycle of ß amyloid-dependent neuronal hyperactivation.31392920Wong B, Lucente DE, MacLean J, Padmanabhan J, Quimby M, Brandt KD, Putcha D, Sherman J, Frosch MP, McGinnis S, Dickerson BCNeurodegenerative disease managementDiagnostic evaluation and monitoring of patients with posterior cortical atrophy. Neurodegener Dis Manag. 2019 08; 9(4):217-239.Neurodegener Dis Manag2019-08-08T00:00:002019Diagnostic evaluation and monitoring of patients with posterior cortical atrophy.Authorship 11822542Authorship 11852295Authorship 118393210331417202Kunkle BW, Grenier-Boley B, Sims R, Bis JC, Damotte V, Naj AC, Boland A, Vronskaya M, van der Lee SJ, Amlie-Wolf A, Bellenguez C, Frizatti A, Chouraki V, Martin ER, Sleegers K, Badarinarayan N, Jakobsdottir J, Hamilton-Nelson KL, Moreno-Grau S, Olaso R, Raybould R, Chen Y, Kuzma AB, Hiltunen M, Morgan T, Ahmad S, Vardarajan BN, Epelbaum J, Hoffmann P, Boada M, Beecham GW, Garnier JG, Harold D, Fitzpatrick AL, Valladares O, Moutet ML, Gerrish A, Smith AV, Qu L, Bacq D, Denning N, Jian X, Zhao Y, Del Zompo M, Fox NC, Choi SH, Mateo I, Hughes JT, Adams HH, Malamon J, Sanchez-Garcia F, Patel Y, Brody JA, Dombroski BA, Naranjo MCD, Daniilidou M, Eiriksdottir G, Mukherjee S, Wallon D, Uphill J, Aspelund T, Cantwell LB, Garzia F, Galimberti D, Hofer E, Butkiewicz M, Fin B, Scarpini E, Sarnowski C, Bush WS, Meslage S, Kornhuber J, White CC, Song Y, Barber RC, Engelborghs S, Sordon S, Voijnovic D, Adams PM, Vandenberghe R, Mayhaus M, Cupples LA, Albert MS, De Deyn PP, Gu W, Himali JJ, Beekly D, Squassina A, Hartmann AM, Orellana A, Blacker D, Rodriguez-Rodriguez E, Lovestone S, Garcia ME, Doody RS, Munoz-Fernadez C, Sussams R, Lin H, Fairchild TJ, Benito YA, Holmes C, Karamujic-Comic H, Frosch MP, Thonberg H, Maier W, Roshchupkin G, Ghetti B, Giedraitis V, Kawalia A, Li S, Huebinger RM, Kilander L, Moebus S, Hernández I, Kamboh MI, Brundin R, Turton J, Yang Q, Katz MJ, Concari L, Lord J, Beiser AS, Keene CD, Helisalmi S, Kloszewska I, Kukull WA, Koivisto AM, Lynch A, Tarraga L, Larson EB, Haapasalo A, Lawlor B, Mosley TH, Lipton RB, Solfrizzi V, Gill M, Longstreth WT, Montine TJ, Frisardi V, Diez-Fairen M, Rivadeneira F, Petersen RC, Deramecourt V, Alvarez I, Salani F, Ciaramella A, Boerwinkle E, Reiman EM, Fievet N, Rotter JI, Reisch JS, Hanon O, Cupidi C, Uitterlinden AGA, Royall DR, Dufouil C, Maletta RG, de Rojas I, Sano M, Brice A, Cecchetti R, George-Hyslop PS, Ritchie K, Tsolaki M, Tsuang DW, Dubois B, Craig D, Wu CK, Soininen H, Avramidou D, Albin RL, Fratiglioni L, Germanou A, Apostolova LG, Keller L, Koutroumani M, Arnold SE, Panza F, Gkatzima O, Asthana S, Hannequin D, Whitehead P, Atwood CS, Caffarra P, Hampel H, Quintela I, Carracedo Á, Lannfelt L, Rubinsztein DC, Barnes LL, Pasquier F, Frölich L, Barral S, McGuinness B, Beach TG, Johnston JA, Becker JT, Passmore P, Bigio EH, Schott JM, Bird TD, Warren JD, Boeve BF, Lupton MK, Bowen JD, Proitsi P, Boxer A, Powell JF, Burke JR, Kauwe JSK, Burns JM, Mancuso M, Buxbaum JD, Bonuccelli U, Cairns NJ, McQuillin A, Cao C, Livingston G, Carlson CS, Bass NJ, Carlsson CM, Hardy J, Carney RM, Bras J, Carrasquillo MM, Guerreiro R, Allen M, Chui HC, Fisher E, Masullo C, Crocco EA, DeCarli C, Bisceglio G, Dick M, Ma L, Duara R, Graff-Radford NR, Evans DA, Hodges A, Faber KM, Scherer M, Fallon KB, Riemenschneider M, Fardo DW, Heun R, Farlow MR, Kölsch H, Ferris S, Leber M, Foroud TM, Heuser I, Galasko DR, Giegling I, Gearing M, Hüll M, Geschwind DH, Gilbert JR, Morris J, Green RC, Mayo K, Growdon JH, Feulner T, Hamilton RL, Harrell LE, Drichel D, Honig LS, Cushion TD, Huentelman MJ, Hollingworth P, Hulette CM, Hyman BT, Marshall R, Jarvik GP, Meggy A, Abner E, Menzies GE, Jin LW, Leonenko G, Real LM, Jun GR, Baldwin CT, Grozeva D, Karydas A, Russo G, Kaye JA, Kim R, Jessen F, Kowall NW, Vellas B, Kramer JH, Vardy E, LaFerla FM, Jöckel KH, Lah JJ, Dichgans M, Leverenz JB, Mann D, Levey AI, Pickering-Brown S, Lieberman AP, Klopp N, Lunetta KL, Wichmann HE, Lyketsos CG, Morgan K, Marson DC, Brown K, Martiniuk F, Medway C, Mash DC, Nöthen MM, Masliah E, Hooper NM, McCormick WC, Daniele A, McCurry SM, Bayer A, McDavid AN, Gallacher J, McKee AC, van den Bussche H, Mesulam M, Brayne C, Miller BL, Riedel-Heller S, Miller CA, Miller JW, Al-Chalabi A, Morris JC, Shaw CE, Myers AJ, Wiltfang J, O'Bryant S, Olichney JM, Alvarez V, Parisi JE, Singleton AB, Paulson HL, Collinge J, Perry WR, Mead S, Peskind E, Cribbs DH, Rossor M, Pierce A, Ryan NS, Poon WW, Nacmias B, Potter H, Sorbi S, et alNature geneticsAuthor Correction: Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates Aß, tau, immunity and lipid processing. Nat Genet. 2019 Sep; 51(9):1423-1424.Nat Genet2019-09-01T00:00:002019Author Correction: Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates Aß, tau, immunity and lipid processing.31405935Hwang J, Bank AM, Mortazavi F, Oakley DH, Frosch MP, Schmahmann JDNeurologySpinal cord a-synuclein deposition associated with myoclonus in patients with MSA-C. Neurology. 2019 08 13; 93(7):302-309.Neurology2019-08-13T00:00:002019Spinal cord a-synuclein deposition associated with myoclonus in patients with MSA-C.31407028Leak RK, Frosch MP, Beach TG, Halliday GMActa neuropathologicaAlpha-synuclein: prion or prion-like? Acta Neuropathol. 2019 10; 138(4):509-514.Acta Neuropathol2019-08-12T00:00:002019Alpha-synuclein: prion or prion-like?Authorship 1191378231514686Charidimou A, Frosch MP, Al-Shahi Salman R, Baron JC, Cordonnier C, Hernandez-Guillamon M, Linn J, Raposo N, Rodrigues M, Romero JR, Schneider JA, Schreiber S, Smith EE, van Buchem MA, Viswanathan A, Wollenweber FA, Werring DJ, Greenberg SMInternational journal of stroke : official journal of the International Stroke SocietyAdvancing diagnostic criteria for sporadic cerebral amyloid angiopathy: Study protocol for a multicenter MRI-pathology validation of Boston criteria v2.0. Int J Stroke. 2019 12; 14(9):956-971.Int J Stroke2019-09-12T00:00:002019Advancing diagnostic criteria for sporadic cerebral amyloid angiopathy: Study protocol for a multicenter MRI-pathology validation of Boston criteria v2.0.Authorship 1572975Authorship 12015211531661038Marquié M, Agüero C, Amaral AC, Villarejo-Galende A, Ramanan P, Chong MST, Sáez-Calveras N, Bennett RE, Verwer EE, Kim SJW, Dhaynaut M, Alvarez VE, Johnson KA, McKee AC, Frosch MP, Gómez-Isla TActa neuropathologica communications[18F]-AV-1451 binding profile in chronic traumatic encephalopathy: a postmortem case series. Acta Neuropathol Commun. 2019 10 28; 7(1):164.Acta Neuropathol Commun2019-10-28T00:00:002019[18F]-AV-1451 binding profile in chronic traumatic encephalopathy: a postmortem case series.Authorship 12047171031750041Williams SR, Juratli TA, Castro BA, Lazaro TT, Gill CM, Nayyar N, Strickland MR, Babinski M, Johnstone SE, Frosch MP, Silverman IM, Ely HA, Kaplan AB, D'Andrea MR, Bihun IV, Hoang K, Batchelor E, Christiansen J, Cahill DP, Barker FG, Brastianos PKJournal of neurological surgery. Part B, Skull baseGenomic Analysis of Posterior Fossa Meningioma Demonstrates Frequent AKT1 E17K Mutations in Foramen Magnum Meningiomas. J Neurol Surg B Skull Base. 2019 Dec; 80(6):562-567.J Neurol Surg B Skull Base2019-01-10T00:00:002019Genomic Analysis of Posterior Fossa Meningioma Demonstrates Frequent AKT1 E17K Mutations in Foramen Magnum Meningiomas.true1Professor of NeurologyProfessor of Neurologytrue1John B. Penney, Jr. Professor of NeurologyJohn B. Penney, Jr. Professor of Neurologytrue1Assistant Professor of PathologyAssistant Professor of Pathologytrue1Professor of NeurologyProfessor of Neurologytrue1Assistant Professor of Pathology, Part-timeAssistant Professor of Pathology, Part-timetrue1Vincent and Stella Coates Professor of Neurologic Diseases in the Department of NeurologyVincent and Stella Coates Professor of Neurologic Diseases in the Department of Neurologytrue1Assistant Professor of RadiologyAssistant Professor of RadiologyAuthorship 1266924Authorship 1363622Authorship 1206716631810839van Veluw SJ, Hou SS, Calvo-Rodriguez M, Arbel-Ornath M, Snyder AC, Frosch MP, Greenberg SM, Bacskai BJNeuronVasomotion as a Driving Force for Paravascular Clearance in the Awake Mouse Brain. 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J Neurol. 2020 Apr; 267(4):1063-1069.J Neurol2019-12-18T00:00:002019Premature vascular disease in young adult stroke: a pathology-based case series.Authorship 1221305231987010van Veluw SJ, Frosch MP, Scherlek AA, Lee D, Greenberg SM, Bacskai BJJournal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and MetabolismIn vivo characterization of spontaneous microhemorrhage formation in mice with cerebral amyloid angiopathy. 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Brain Commun. 2022; 4(3):fcac074.Brain Commun2022-03-25T00:00:002022Quantitative and histologically validated measures of the entorhinal subfields in ex vivo MRI.true1Associate Professor of Pathology, Part-timeAssociate Professor of Pathology, Part-timeAuthorship 3593618Authorship 359523335852437Dias-Santagata D, Heist RS, Bard AZ, da Silva AFL, Dagogo-Jack I, Nardi V, Ritterhouse LL, Spring LM, Jessop N, Farahani AA, Mino-Kenudson M, Allen J, Goyal L, Parikh A, Misdraji J, Shankar G, Jordan JT, Martinez-Lage M, Frosch M, Graubert T, Fathi AT, Hobbs GS, Hasserjian RP, Raje N, Abramson J, Schwartz JH, Sullivan RJ, Miller D, Hoang MP, Isakoff S, Ly A, Bouberhan S, Watkins J, Oliva E, Wirth L, Sadow PM, Faquin W, Cote GM, Hung YP, Gao X, Wu CL, Garg S, Rivera M, Le LP, John Iafrate A, Juric D, Hochberg EP, Clark J, Bardia A, Lennerz JKThe oncologistImplementation and Clinical Adoption of Precision Oncology Workflows Across a Healthcare Network. 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NeurologyThe Boston criteria version 2.0 for cerebral amyloid angiopathy: a multicentre, retrospective, MRI-neuropathology diagnostic accuracy study. Lancet Neurol. 2022 08; 21(8):714-725.Lancet Neurol2022-08-01T00:00:002022The Boston criteria version 2.0 for cerebral amyloid angiopathy: a multicentre, retrospective, MRI-neuropathology diagnostic accuracy study.35706413Alvarez-Breckenridge C, Markson SC, Stocking JH, Nayyar N, Lastrapes M, Strickland MR, Kim AE, de Sauvage M, Dahal A, Larson JM, Mora JL, Navia AW, Klein RH, Kuter BM, Gill CM, Bertalan M, Shaw B, Kaplan A, Subramanian M, Jain A, Kumar S, Danish H, White M, Shahid O, Pauken KE, Miller BC, Frederick DT, Hebert C, Shaw M, Martinez-Lage M, Frosch M, Wang N, Gerstner E, Nahed BV, Curry WT, Carter B, Cahill DP, Boland GM, Izar B, Davies MA, Sharpe AH, Suvà ML, Sullivan RJ, Brastianos PK, Carter SLCancer immunology researchMicroenvironmental Landscape of Human Melanoma Brain Metastases in Response to Immune Checkpoint Inhibition. Cancer Immunol Res. 2022 08 03; 10(8):996-1012.Cancer Immunol Res2022-08-03T00:00:002022Microenvironmental Landscape of Human Melanoma Brain Metastases in Response to Immune Checkpoint Inhibition.36190676Ndayisaba A, Pitaro AT, Willett AS, Jones KA, de Gusmao CM, Olsen AL, Kim J, Rissanen E, Woods JK, Srinivasan SR, Nagy A, Nagy A, Mesidor M, Cicero S, Patel V, Oakley DH, Tuncali I, Taglieri-Noble K, Clark EC, Paulson J, Krolewski RC, Ho GP, Hung AY, Wills AM, Hayes MT, Macmore JP, Warren L, Bower PG, Langer CB, Kellerman LR, Humphreys CW, Glanz BI, Dielubanza EJ, Frosch MP, Freeman RL, Gibbons CH, Stefanova N, Chitnis T, Weiner HL, Scherzer CR, Scholz SW, Vuzman D, Cox LM, Wenning G, Schmahmann JD, Gupta AS, Novak P, Young GS, Feany MB, Singhal T, Khurana VCerebellum (London, England)Clinical Trial-Ready Patient Cohorts for Multiple System Atrophy: Coupling Biospecimen and iPSC Banking to Longitudinal Deep-Phenotyping. Cerebellum. 2024 Feb; 23(1):31-51.Cerebellum2022-10-03T00:00:002022Clinical Trial-Ready Patient Cohorts for Multiple System Atrophy: Coupling Biospecimen and iPSC Banking to Longitudinal Deep-Phenotyping.Authorship 14719694Authorship 15005316Authorship 148562711Authorship 149614334Authorship 14999596Authorship 149365020Authorship 1471876535997131Hopfner F, Tietz AK, Ruf VC, Ross OA, Koga S, Dickson D, Aguzzi A, Attems J, Beach T, Beller A, Cheshire WP, van Deerlin V, Desplats P, Deuschl G, Duyckaerts C, Ellinghaus D, Evsyukov V, Flanagan ME, Franke A, Frosch MP, Gearing M, Gelpi E, van Gerpen JA, Ghetti B, Glass JD, Grinberg LT, Halliday G, Helbig I, Höllerhage M, Huitinga I, Irwin DJ, Keene DC, Kovacs GG, Lee EB, Levin J, Martí MJ, Mackenzie I, McKeith I, Mclean C, Mollenhauer B, Neumann M, Newell KL, Pantelyat A, Pendziwiat M, Peters A, Molina Porcel L, Rabano A, Matej R, Rajput A, Rajput A, Reimann R, Scott WK, Seeley W, Selvackadunco S, Simuni T, Stadelmann C, Svenningsson P, Thomas A, Trenkwalder C, Troakes C, Trojanowski JQ, Uitti RJ, White CL, Wszolek ZK, Xie T, Ximelis T, Yebenes J, Müller U, Schellenberg GD, Herms J, Kuhlenbäumer G, Höglinger GMovement disorders : official journal of the Movement Disorder SocietyCommon Variants Near ZIC1 and ZIC4 in Autopsy-Confirmed Multiple System Atrophy. Mov Disord. 2022 10; 37(10):2110-2121.Mov Disord2022-08-23T00:00:002022Common Variants Near ZIC1 and ZIC4 in Autopsy-Confirmed Multiple System Atrophy.36147770Kons ZA, Regenhardt RW, Dmytriw AA, Vranic JE, Huynh A, Frosch MP, Borges LF, Patel AB, Romero JM, Stapleton CJThe NeurohospitalistT2 Hypointense Schwannoma Masquerading As A Vascular Lesion: A Case Report. Neurohospitalist. 2022 Oct; 12(4):659-663.Neurohospitalist2022-07-01T00:00:002022T2 Hypointense Schwannoma Masquerading As A Vascular Lesion: A Case Report.36251576Josephy-Hernandez S, Brickhouse M, Champion S, Kim DD, Touroutoglou A, Frosch M, Dickerson BCNeurocaseClinical, radiologic, and pathologic features of the globular glial tauopathy subtype of frontotemporal lobar degeneration in right temporal variant frontotemporal dementia with salient features of Geschwind syndrome. Neurocase. 2022 08; 28(4):375-381.Neurocase2022-10-17T00:00:002022Clinical, radiologic, and pathologic features of the globular glial tauopathy subtype of frontotemporal lobar degeneration in right temporal variant frontotemporal dementia with salient features of Geschwind syndrome.9929024Harmsen D, Rothgänger J, Singer C, Albert J, Frosch MLancet (London, England)Intuitive hypertext-based molecular identification of micro-organisms. Lancet. 1999 Jan 23; 353(9149):291.Lancet1999-01-23T00:00:001999Intuitive hypertext-based molecular identification of micro-organisms.1349121Wollenhaupt J, Hartmann F, Zeidler H, Frosch MLancet (London, England)Staphylococcus aureus in urine and false-positive immunoassay for Chlamydia. Lancet. 1992 May 02; 339(8801):1110.Lancet1992-05-02T00:00:001992Staphylococcus aureus in urine and false-positive immunoassay for Chlamydia.36201019Wu Z, Rajan S, Chung HJ, Raffeld M, Panneer Selvam P, Schweizer L, Perry A, Samuel D, Giannini C, Ragunathan A, Frosch MP, Marshall MS, Boué DR, Donev K, Neill SG, Fernandes I, Resnick A, Rood B, Cummings TJ, Buckley AF, Szymanski L, Neto OLA, Zach L, Colman H, Cheshier S, Ziskin J, Tyagi M, Capper D, Abdullaev Z, Cimino PJ, Quezado M, Pratt D, Aldape KActa neuropathologicaMolecular and clinicopathologic characteristics of gliomas with EP300::BCOR fusions. Acta Neuropathol. 2022 12; 144(6):1175-1178.Acta Neuropathol2022-10-06T00:00:002022Molecular and clinicopathologic characteristics of gliomas with EP300::BCOR fusions.36456723Ndayisaba A, Pitaro AT, Willett AS, Jones KA, de Gusmao CM, Olsen AL, Kim J, Rissanen E, Woods JK, Srinivasan SR, Nagy A, Nagy A, Mesidor M, Cicero S, Patel V, Oakley DH, Tuncali I, Taglieri-Noble K, Clark EC, Paulson J, Krolewski RC, Ho GP, Hung AY, Wills AM, Hayes MT, Macmore JP, Warren L, Bower PG, Langer CB, Kellerman LR, Humphreys CW, Glanz BI, Dielubanza EJ, Frosch MP, Freeman RL, Gibbons CH, Stefanova N, Chitnis T, Weiner HL, Scherzer CR, Scholz SW, Vuzman D, Cox LM, Wenning G, Schmahmann JD, Gupta AS, Novak P, Young GS, Feany MB, Singhal T, Khurana VCerebellum (London, England)Correction to: Clinical trial-ready patient cohorts for multiple system atrophy: coupling biospecimen and iPSC banking to longitudinal deep-phenotyping. Cerebellum. 2024 Feb; 23(1):52-53.Cerebellum2024-02-01T00:00:002024Correction to: Clinical trial-ready patient cohorts for multiple system atrophy: coupling biospecimen and iPSC banking to longitudinal deep-phenotyping.Authorship 150770034Authorship 15146395Authorship 1514658236600730Leavitt L, Baohan A, Heller H, Kozanno L, Frosch MP, Dunn GSurgical neurology internationalSurgical management of an abscess of the insula. Surg Neurol Int. 2022; 13:591.Surg Neurol Int2022-12-23T00:00:002022Surgical management of an abscess of the insula.36601621Dickson JR, Frosch MP, Hyman BTBrain communicationsAltered localization of nucleoporin 98 in primary tauopathies. Brain Commun. 2023; 5(1):fcac334.Brain Commun2022-12-22T00:00:002022Altered localization of nucleoporin 98 in primary tauopathies.Authorship 15202092136681782Nicks R, Clement NF, Alvarez VE, Tripodis Y, Baucom ZH, Huber BR, Mez J, Alosco ML, Aytan N, Cherry JD, Cormier KA, Kubilius C, Mathias R, Svirsky SE, Pothast MJ, Hildebrandt AM, Chung J, Han X, Crary JF, McKee AC, Frosch MP, Stein TDActa neuropathologicaRepetitive head impacts and chronic traumatic encephalopathy are associated with TDP-43 inclusions and hippocampal sclerosis. Acta Neuropathol. 2023 04; 145(4):395-408.Acta Neuropathol2023-01-21T00:00:002023Repetitive head impacts and chronic traumatic encephalopathy are associated with TDP-43 inclusions and hippocampal sclerosis.Authorship 15244996Authorship 15243981136804377Halvorsen SC, Benita Y, Hopton M, Hoppe B, Gunnlaugsson HO, Korgaonkar P, Vanderburg CR, Nielsen GP, Trepanowski N, Cheah JH, Frosch MP, Schwab JH, Rosenberg AE, Hornicek FJ, Sassi SThe American journal of pathologyTranscriptional Profiling Supports the Notochordal Origin of Chordoma and Its Dependence on a TGFB1-TBXT Network. Am J Pathol. 2023 05; 193(5):532-547.Am J Pathol2023-02-17T00:00:002023Transcriptional Profiling Supports the Notochordal Origin of Chordoma and Its Dependence on a TGFB1-TBXT Network.36805433Gritsch S, Aghajan Y, Kozanno L, Chiu D, Jordan JT, Frosch MP, Shankar G, Kimberly WTNeurologyTeaching NeuroImage: Subacute Quadriparesis From Intramedullary Spinal Cord Infiltrating Glioma With TERT Promoter Mutation. Neurology. 2023 06 13; 100(24):1164-1165.Neurology2023-02-20T00:00:002023Teaching NeuroImage: Subacute Quadriparesis From Intramedullary Spinal Cord Infiltrating Glioma With TERT Promoter Mutation.Authorship 1527922636843959Williams EM, Rosenblum EW, Pihlstrom N, Llamas-Rodríguez J, Champion S, Frosch MP, Augustinack JCFrontiers in neuroanatomyPentad: A reproducible cytoarchitectonic protocol and its application to parcellation of the human hippocampus. Front Neuroanat. 2023; 17:1114757.Front Neuroanat2023-02-09T00:00:002023Pentad: A reproducible cytoarchitectonic protocol and its application to parcellation of the human hippocampus.Authorship 1532340936899414Wang Z, Jin M, Hong W, Liu W, Reczek D, Lagomarsino VN, Hu Y, Weeden T, Frosch MP, Young-Pearse TL, Pradier L, Selkoe D, Walsh DMActa neuropathologica communicationsLearnings about Aß from human brain recommend the use of a live-neuron bioassay for the discovery of next generation Alzheimer's disease immunotherapeutics. Acta Neuropathol Commun. 2023 03 10; 11(1):39.Acta Neuropathol Commun2023-03-10T00:00:002023Learnings about Aß from human brain recommend the use of a live-neuron bioassay for the discovery of next generation Alzheimer's disease immunotherapeutics.Authorship 15338381636937522Kivisäkk P, Carlyle BC, Sweeney T, Trombetta BA, LaCasse K, El-Mufti L, Tuncali I, Chibnik LB, Das S, Scherzer CR, Johnson KA, Dickerson BC, Gomez-Isla T, Blacker D, Oakley DH, Frosch MP, Hyman BT, Aghvanyan A, Bathala P, Campbell C, Sigal G, Stengelin M, Arnold SEFrontiers in neurologyPlasma biomarkers for diagnosis of Alzheimer's disease and prediction of cognitive decline in individuals with mild cognitive impairment. Front Neurol. 2023; 14:1069411.Front Neurol2023-03-02T00:00:002023Plasma biomarkers for diagnosis of Alzheimer's disease and prediction of cognitive decline in individuals with mild cognitive impairment.Authorship 19802237059743Merrihew GE, Park J, Plubell D, Searle BC, Keene CD, Larson EB, Bateman R, Perrin RJ, Chhatwal JP, Farlow MR, McLean CA, Ghetti B, Newell KL, Frosch MP, Montine TJ, MacCoss MJScientific dataA peptide-centric quantitative proteomics dataset for the phenotypic assessment of Alzheimer's disease. Sci Data. 2023 04 14; 10(1):206.Sci Data2023-04-14T00:00:002023A peptide-centric quantitative proteomics dataset for the phenotypic assessment of Alzheimer's disease.Authorship 483349323787894Kay KR, Smith C, Wright AK, Serrano-Pozo A, Pooler AM, Koffie R, Bastin ME, Bak TH, Abrahams S, Kopeikina KJ, McGuone D, Frosch MP, Gillingwater TH, Hyman BT, Spires-Jones TLNature protocolsStudying synapses in human brain with array tomography and electron microscopy. Nat Protoc. 2013; 8(7):1366-80.Nat Protoc2013-06-20T00:00:002013Studying synapses in human brain with array tomography and electron microscopy.true1Professor of PathologyProfessor of Pathologytrue1Associate Professor of NeurologyAssociate Professor of NeurologyAuthorship 15591453Authorship 156142546Authorship 1555549100Authorship 156287414Authorship 15614868Authorship 15606115Authorship 15716001837037195Llamas-Rodríguez J, Oltmer J, Marshall M, Champion S, Frosch MP, Augustinack JCBrain pathology (Zurich, Switzerland)TDP-43 and tau concurrence in the entorhinal subfields in primary age-related tauopathy and preclinical Alzheimer's disease. Brain Pathol. 2023 07; 33(4):e13159.Brain Pathol2023-04-10T00:00:002023TDP-43 and tau concurrence in the entorhinal subfields in primary age-related tauopathy and preclinical Alzheimer's disease.37041300Oltmer J, Rosenblum EW, Williams EM, Roy J, Llamas-Rodriguez J, Perosa V, Champion SN, Frosch MP, Augustinack JCScientific reportsStereology neuron counts correlate with deep learning estimates in the human hippocampal subregions. Sci Rep. 2023 04 11; 13(1):5884.Sci Rep2023-04-11T00:00:002023Stereology neuron counts correlate with deep learning estimates in the human hippocampal subregions.37163045Valentino RR, Scotton WJ, Roemer SF, Lashley T, Heckman MG, Shoai M, Martinez-Carrasco A, Tamvaka N, Walton RL, Baker MC, Macpherson HL, Real R, Soto-Beasley AI, Mok K, Revesz T, Warner TT, Jaunmuktane Z, Boeve BF, Christopher EA, DeTure M, Duara R, Graff-Radford NR, Josephs KA, Knopman DS, Koga S, Murray ME, Lyons KE, Pahwa R, Parisi JE, Petersen RC, Whitwell J, Grinberg LT, Miller B, Schlereth A, Seeley WW, Spina S, Grossman M, Irwin DJ, Lee EB, Suh E, Trojanowski JQ, Van Deerlin VM, Wolk DA, Connors TR, Dooley PM, Frosch MP, Oakley DH, Aldecoa I, Balasa M, Gelpi E, Borrego-Écija S, de Eugenio Huélamo RM, Gascon-Bayarri J, Sánchez-Valle R, Sanz-Cartagena P, Piñol-Ripoll G, Molina-Porcel L, Bigio EH, Flanagan ME, Gefen T, Rogalski EJ, Weintraub S, Redding-Ochoa J, Chang K, Troncoso JC, Prokop S, Newell KL, Ghetti B, Jones M, Richardson A, Robinson AC, Roncaroli F, Snowden J, Allinson K, Green O, Rowe JB, Singh P, Beach TG, Serrano GE, Flowers XE, Goldman JE, Heaps AC, Leskinen SP, Teich AF, Black SE, Keith JL, Masellis M, Bodi I, King A, Sarraj SA, Troakes C, Halliday GM, Hodges JR, Kril JJ, Kwok JB, Piguet O, Gearing M, Arzberger T, Roeber S, Attems J, Morris CM, Thomas AJ, Evers BM, White CL, Mechawar N, Sieben AA, Cras PP, De Vil BB, De Deyn PPPP, Duyckaerts C, Le Ber I, Seihean D, Turbant-Leclere S, MacKenzie IR, McLean C, Cykowski MD, Ervin JF, Wang SJ, Graff C, Nennesmo I, Nagra RM, Riehl J, Kovacs GG, Giaccone G, Nacmias B, Neumann M, Ang LC, Finger EC, Blauwendraat C, Nalls MA, Singleton AB, Vitale D, Cunha C, Carvalho A, Wszolek ZK, Morris HR, Rademakers R, Hardy JA, Dickson DW, Rohrer JD, Ross OAmedRxiv : the preprint server for health sciencesCreating the Pick's disease International Consortium: Association study of MAPT H2 haplotype with risk of Pick's disease. medRxiv. 2023 Apr 24.medRxiv2023-04-24T00:00:002023Creating the Pick's disease International Consortium: Association study of MAPT H2 haplotype with risk of Pick's disease.36993722Vardalaki D, Pham TLD, Frosch MP, Cosgrove GR, Richardson M, Cash SS, Harnett MTbioRxiv : the preprint server for biologyPatch2MAP combines patch-clamp electrophysiology with super-resolution structural and protein imaging in identified single neurons without genetic modification. bioRxiv. 2023 Mar 21.bioRxiv2023-03-21T00:00:002023Patch2MAP combines patch-clamp electrophysiology with super-resolution structural and protein imaging in identified single neurons without genetic modification.37333251Gazula H, Tregidgo HFJ, Billot B, Balbastre Y, William-Ramirez J, Herisse R, Deden-Binder LJ, Casamitjana A, Melief EJ, Latimer CS, Kilgore MD, Montine M, Robinson E, Blackburn E, Marshall MS, Connors TR, Oakley DH, Frosch MP, Young SI, Van Leemput K, Dalca AV, FIschl B, Mac Donald CL, Keene CD, Hyman BT, Iglesias JEbioRxiv : the preprint server for biologyMachine learning of dissection photographs and surface scanning for quantitative 3D neuropathology. bioRxiv. 2024 Jan 30.bioRxiv2024-01-30T00:00:002024Machine learning of dissection photographs and surface scanning for quantitative 3D neuropathology.37461624Rajabli F, Benchek P, Tosto G, Kushch N, Sha J, Bazemore K, Zhu C, Lee WP, Haut J, Hamilton-Nelson KL, Wheeler NR, Zhao Y, Farrell JJ, Grunin MA, Leung YY, Kuksa PP, Li D, Lucio da Fonseca E, Mez JB, Palmer EL, Pillai J, Sherva RM, Song YE, Zhang X, Iqbal T, Pathak O, Valladares O, Kuzma AB, Abner E, Adams PM, Aguirre A, Albert MS, Albin RL, Allen M, Alvarez L, Apostolova LG, Arnold SE, Asthana S, Atwood CS, Ayres G, Baldwin CT, Barber RC, Barnes LL, Barral S, Beach TG, Becker JT, Beecham GW, Beekly D, Benitez BA, Bennett D, Bertelson J, Bird TD, Blacker D, Boeve BF, Bowen JD, Boxer A, Brewer J, Burke JR, Burns JM, Buxbaum JD, Cairns NJ, Cantwell LB, Cao C, Carlson CS, Carlsson CM, Carney RM, Carrasquillo MM, Chasse S, Chesselet MF, Chin NA, Chui HC, Chung J, Craft S, Crane PK, Cribbs DH, Crocco EA, Cruchaga C, Cuccaro ML, Cullum M, Darby E, Davis B, De Jager PL, DeCarli C, DeToledo J, Dick M, Dickson DW, Dombroski BA, Doody RS, Duara R, Ertekin-Taner N, Evans DA, Faber KM, Fairchild TJ, Fallon KB, Fardo DW, Farlow MR, Fernandez-Hernandez V, Ferris S, Foroud TM, Frosch MP, Fulton-Howard B, Galasko DR, Gamboa A, Gearing M, Geschwind DH, Ghetti B, Gilbert JR, Goate AM, Grabowski TJ, Graff-Radford NR, Green RC, Growdon JH, Hakonarson H, Hall J, Hamilton RL, Harari O, Hardy J, Harrell LE, Head E, Henderson VW, Hernandez M, Hohman T, Honig LS, Huebinger RM, Huentelman MJ, Hulette CM, Hyman BT, Hynan LS, Ibanez L, Jarvik GP, Jayadev S, Jin LW, Johnson K, Johnson L, Kamboh MI, Karydas AM, Katz MJ, Kauwe JS, Kaye JA, Keene CD, Khaleeq A, Kim R, Knebl J, Kowall NW, Kramer JH, Kukull WA, LaFerla FM, Lah JJ, Larson EB, Lerner A, Leverenz JB, Levey AI, Lieberman AP, Lipton RB, Logue M, Lopez OL, Lunetta KL, Lyketsos CG, Mains D, Margaret FE, Marson DC, Martin ERR, Martiniuk F, Mash DC, Masliah E, Massman P, Masurkar A, McCormick WC, McCurry SM, McDavid AN, McDonough S, McKee AC, Mesulam M, Miller BL, Miller CA, Miller JW, Montine TJ, Monuki ES, Morris JC, Mukherjee S, Myers AJ, Nguyen T, O'Bryant S, Olichney JM, Ory M, Palmer R, Parisi JE, Paulson HL, Pavlik V, Paydarfar D, Perez V, Peskind E, Petersen RC, Pierce A, Polk M, Poon WW, Potter H, Qu L, Quiceno M, Quinn JF, Raj A, Raskind M, Reiman EM, Reisberg B, Reisch JS, Ringman JM, Roberson ED, Rodriguear M, Rogaeva E, Rosen HJ, Rosenberg RN, Royall DR, Sager MA, Sano M, Saykin AJ, Schneider JA, Schneider LS, Seeley WW, Slifer SH, Small S, Smith AG, Smith JP, Sonnen JA, Spina S, St George-Hyslop P, Stern RA, Stevens AB, Strittmatter SM, Sultzer D, Swerdlow RH, Tanzi RE, Tilson JL, Trojanowski JQ, Troncoso JC, Tsuang DW, Van Deerlin VM, van Eldik LJ, Vance JM, Vardarajan BN, Vassar R, Vinters HV, Vonsattel JP, Weintraub S, Welsh-Bohmer KA, Whitehead PL, Wijsman EM, Wilhelmsen KC, Williams B, Williamson J, Wilms H, Wingo TS, Wisniewski T, Woltjer RL, Woon M, Wright CB, Wu CK, Younkin SG, Yu CE, Yu L, Zhu X, Kunkle BW, Bush WS, Wang LS, Farrer LA, Haines JL, Mayeux R, Pericak-Vance MA, Schellenberg GD, Jun GR, Reitz C, Naj ACmedRxiv : the preprint server for health sciencesMulti-ancestry genome-wide meta-analysis of 56,241 individuals identifies LRRC4C, LHX5-AS1 and nominates ancestry-specific loci PTPRK , GRB14 , and KIAA0825 as novel risk loci for Alzheimer's disease: the Alzheimer's Disease Genetics Consortium. medRxiv. 2023 Jul 08.medRxiv2023-07-08T00:00:002023Multi-ancestry genome-wide meta-analysis of 56,241 individuals identifies LRRC4C, LHX5-AS1 and nominates ancestry-specific loci PTPRK , GRB14 , and KIAA0825 as novel risk loci for Alzheimer's disease: the Alzheimer's Disease Genetics Consortium.Authorship 15893723Authorship 15932265Authorship 159047112Authorship 1587732937733036Mate de Gerando A, Quittot N, Frosch MP, Hyman BTActa neuropathologicaReply: Soluble oligomers or insoluble fibrils? Acta Neuropathol. 2023 12; 146(6):863-866.Acta Neuropathol2023-09-21T00:00:002023Reply: Soluble oligomers or insoluble fibrils?37646002Sepulveda-Falla D, Lanau CAV, White C, Serrano GE, Acosta-Uribe J, Mejía-Cupajita B, Villalba-Moreno ND, Lu P, Glatzel M, Kofler JK, Ghetti B, Frosch MP, Restrepo FL, Kosik KS, Beach TGmedRxiv : the preprint server for health sciencesComorbidities in Early-Onset Sporadic versus Presenilin-1 Mutation-Associated Alzheimer's Disease Dementia: Evidence for Dependency on Alzheimer's Disease Neuropathological Changes. medRxiv. 2023 Aug 16.medRxiv2023-08-16T00:00:002023Comorbidities in Early-Onset Sporadic versus Presenilin-1 Mutation-Associated Alzheimer's Disease Dementia: Evidence for Dependency on Alzheimer's Disease Neuropathological Changes.37700618Oltmer J, Greve DN, Cerri S, Slepneva N, Llamas-Rodríguez J, Iglesias JE, Van Leemput K, Champion SN, Frosch MP, Augustinack JCThe Journal of comparative neurologyAssessing individual variability of the entorhinal subfields in health and disease. 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Sci Adv. 2023 10 13; 9(41):eadg3844.Sci Adv2023-10-12T00:00:002023A cellular resolution atlas of Broca's area.37814356Greenberg ABW, Mehta NH, Mekbib KY, Kiziltug E, Smith HR, Hyman BT, Chan D, Curry WT, Arnold SE, Frosch MP, Duy PQ, Kahle KTCerebral cortex (New York, N.Y. : 1991)Cases of familial idiopathic normal pressure hydrocephalus implicate genetic factors in disease pathogenesis. Cereb Cortex. 2023 Nov 27; 33(23):11400-11407.Cereb Cortex2023-11-27T00:00:002023Cases of familial idiopathic normal pressure hydrocephalus implicate genetic factors in disease pathogenesis.37812432Taddei RN, Perbet R, Mate de Gerando A, Wiedmer AE, Sanchez-Mico M, Connors Stewart T, Gaona A, Melloni A, Amaral AC, Duff K, Frosch MP, Gómez-Isla TJAMA neurologyTau Oligomer-Containing Synapse Elimination by Microglia and Astrocytes in Alzheimer Disease. JAMA Neurol. 2023 Nov 01; 80(11):1209-1221.JAMA Neurol2023-11-01T00:00:002023Tau Oligomer-Containing Synapse Elimination by Microglia and Astrocytes in Alzheimer Disease.true1Professor of RadiologyProfessor of RadiologyAuthorship 1602019137872367Frosch M, Demerath T, Fung C, Prinz M, Urbach H, Erny D, Taschner CAClinical neuroradiologyFreiburg Neuropathology Case Conference : Headache, Mental Confusion and Mild Hemiparesis in a 68-year-old Patient. Clin Neuroradiol. 2023 12; 33(4):1159-1164.Clin Neuroradiol2023-10-23T00:00:002023Freiburg Neuropathology Case Conference : Headache, Mental Confusion and Mild Hemiparesis in a 68-year-old Patient.Authorship 46417413Authorship 4856503Authorship 1613279738062617Gong Y, Laheji F, Berenson A, Li Y, Moser A, Qian A, Frosch M, Sadjadi R, Hahn R, Maguire CA, Eichler FAnnals of neurologyRole of Basal Forebrain Neurons in Adrenomyeloneuropathy in Mice and Humans. Ann Neurol. 2024 Mar; 95(3):442-458.Ann Neurol2023-12-26T00:00:002023Role of Basal Forebrain Neurons in Adrenomyeloneuropathy in Mice and Humans.Authorship 5317295Authorship 1619693438189522Amaral DG, Augustinack J, Barbas H, Frosch M, Gabrieli J, Luebke J, Rakic P, Rosene D, Rushmore RJHippocampusThe analysis of H.M.'s brain: A brief review of status and plans for future studies and tissue archive. Hippocampus. 2024 Feb; 34(2):52-57.Hippocampus2024-01-08T00:00:002024The analysis of H.M.'s brain: A brief review of status and plans for future studies and tissue archive.Authorship 5508393Authorship 162405214Authorship 16230581138275188Greenberg ABW, Mekbib KY, Mehta NH, Kiziltug E, Duy PQ, Smith HR, Junkkari A, Leinonen V, Hyman BT, Chan D, Curry WT, Arnold SE, Barker Ii FG, Frosch MP, Kahle KTCerebral cortex (New York, N.Y. : 1991)Utility of cortical tissue analysis in normal pressure hydrocephalus. 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Mov Disord Clin Pract. 2024 Jan 23.Mov Disord Clin Pract2024-01-23T00:00:002024Gerstmann-Sträussler-Scheinker Disease Presenting as Late-Onset Slowly Progressive Spinocerebellar Ataxia, and Comparative Case Series with Neuropathology.Authorship 16257201138280071Aguero C, Dhaynaut M, Amaral AC, Moon SH, Neelamegam R, Scapellato M, Carazo-Casas C, Kumar S, El Fakhri G, Johnson K, Frosch MP, Normandin MD, Gómez-Isla TActa neuropathologicaHead-to-head comparison of [18F]-Flortaucipir, [18F]-MK-6240 and [18F]-PI-2620 postmortem binding across the spectrum of neurodegenerative diseases. Acta Neuropathol. 2024 Jan 27; 147(1):25.Acta Neuropathol2024-01-27T00:00:002024Head-to-head comparison of [18F]-Flortaucipir, [18F]-MK-6240 and [18F]-PI-2620 postmortem binding across the spectrum of neurodegenerative diseases.Authorship 17263211Authorship 2346473Authorship 5756854Authorship 2276289Authorship 3503006Authorship 2690849Authorship 32119313Authorship 65495112Authorship 6533284Authorship 6521486Authorship 745465Authorship 784564Authorship 5394283Authorship 5603173Authorship 2315552Authorship 674156823818064Arbel-Ornath M, Hudry E, Eikermann-Haerter K, Hou S, Gregory JL, Zhao L, Betensky RA, Frosch MP, Greenberg SM, Bacskai BJActa neuropathologicaInterstitial fluid drainage is impaired in ischemic stroke and Alzheimer's disease mouse models. Acta Neuropathol. 2013 Sep; 126(3):353-64.Acta Neuropathol2013-07-02T00:00:002013Interstitial fluid drainage is impaired in ischemic stroke and Alzheimer's disease mouse models.Authorship 681558423467193McFarland NR, Burdett T, Desjardins CA, Frosch MP, Schwarzschild MANeuro-degenerative diseasesPostmortem brain levels of urate and precursors in Parkinson's disease and related disorders. Neurodegener Dis. 2013; 12(4):189-98.Neurodegener Dis2013-02-28T00:00:002013Postmortem brain levels of urate and precursors in Parkinson's disease and related disorders.Authorship 319212Authorship 6937214Authorship 6934133Authorship 69367848803950Vogel U, Steinmetz I, Frosch MMedical microbiology and immunologyAvoiding artifacts in the infant rat model for bacterial meningitis: use of Sangur test strips for the rapid quantification of blood contamination in cerebrospinal fluid. Med Microbiol Immunol. 1996 May; 185(1):27-30.Med Microbiol Immunol1996-05-01T00:00:001996Avoiding artifacts in the infant rat model for bacterial meningitis: use of Sangur test strips for the rapid quantification of blood contamination in cerebrospinal fluid.9003770Mühlenhoff M, Eckhardt M, Bethe A, Frosch M, Gerardy-Schahn RThe EMBO journalAutocatalytic polysialylation of polysialyltransferase-1. EMBO J. 1996 Dec 16; 15(24):6943-50.EMBO J1996-12-16T00:00:001996Autocatalytic polysialylation of polysialyltransferase-1.24226270Serrano-Pozo A, Qian J, Monsell SE, Frosch MP, Betensky RA, Hyman BTJournal of neuropathology and experimental neurologyExamination of the clinicopathologic continuum of Alzheimer disease in the autopsy cohort of the National Alzheimer Coordinating Center. J Neuropathol Exp Neurol. 2013 Dec; 72(12):1182-92.J Neuropathol Exp Neurol2013-12-01T00:00:002013Examination of the clinicopathologic continuum of Alzheimer disease in the autopsy cohort of the National Alzheimer Coordinating Center.Authorship 696601524041872Magnain C, Augustinack JC, Reuter M, Wachinger C, Frosch MP, Ragan T, Akkin T, Wedeen VJ, Boas DA, Fischl BNeuroImageBlockface histology with optical coherence tomography: a comparison with Nissl staining. Neuroimage. 2014 Jan 01; 84:524-33.Neuroimage2013-09-13T00:00:002013Blockface histology with optical coherence tomography: a comparison with Nissl staining.Authorship 1942025Authorship 260837424585367Serrano-Pozo A, Qian J, Monsell SE, Blacker D, Gómez-Isla T, Betensky RA, Growdon JH, Johnson KA, Frosch MP, Sperling RA, Hyman BTAnnals of neurologyMild to moderate Alzheimer dementia with insufficient neuropathological changes. Ann Neurol. 2014 Apr; 75(4):597-601.Ann Neurol2014-04-08T00:00:002014Mild to moderate Alzheimer dementia with insufficient neuropathological changes.Authorship 2943547Authorship 4235462Authorship 4602767Authorship 2781911Authorship 72542311Authorship 72475810Authorship 7187111624473151Annese J, Schenker-Ahmed NM, Bartsch H, Maechler P, Sheh C, Thomas N, Kayano J, Ghatan A, Bresler N, Frosch MP, Klaming R, Corkin SNature communicationsPostmortem examination of patient H.M.'s brain based on histological sectioning and digital 3D reconstruction. Nat Commun. 2014; 5:3122.Nat Commun2014-01-01T00:00:002014Postmortem examination of patient H.M.'s brain based on histological sectioning and digital 3D reconstruction.24442578Gallagher MD, Suh E, Grossman M, Elman L, McCluskey L, Van Swieten JC, Al-Sarraj S, Neumann M, Gelpi E, Ghetti B, Rohrer JD, Halliday G, Van Broeckhoven C, Seilhean D, Shaw PJ, Frosch MP, Alafuzoff I, Antonell A, Bogdanovic N, Brooks W, Cairns NJ, Cooper-Knock J, Cotman C, Cras P, Cruts M, De Deyn PP, DeCarli C, Dobson-Stone C, Engelborghs S, Fox N, Galasko D, Gearing M, Gijselinck I, Grafman J, Hartikainen P, Hatanpaa KJ, Highley JR, Hodges J, Hulette C, Ince PG, Jin LW, Kirby J, Kofler J, Kril J, Kwok JB, Levey A, Lieberman A, Llado A, Martin JJ, Masliah E, McDermott CJ, McKee A, McLean C, Mead S, Miller CA, Miller J, Munoz DG, Murrell J, Paulson H, Piguet O, Rossor M, Sanchez-Valle R, Sano M, Schneider J, Silbert LC, Spina S, van der Zee J, Van Langenhove T, Warren J, Wharton SB, White CL, Woltjer RL, Trojanowski JQ, Lee VM, Van Deerlin V, Chen-Plotkin ASActa neuropathologicaTMEM106B is a genetic modifier of frontotemporal lobar degeneration with C9orf72 hexanucleotide repeat expansions. Acta Neuropathol. 2014 Mar; 127(3):407-18.Acta Neuropathol2014-01-19T00:00:002014TMEM106B is a genetic modifier of frontotemporal lobar degeneration with C9orf72 hexanucleotide repeat expansions.24709683Bit-Ivan EN, Suh E, Shim HS, Weintraub S, Hyman BT, Arnold SE, McCarty-Wood E, Van Deerlin VM, Schneider JA, Trojanowski JQ, Frosch MP, Baker MC, Rademakers R, Mesulam M, Bigio EHJournal of neuropathology and experimental neurologyA novel GRN mutation (GRN c.708+6_+9delTGAG) in frontotemporal lobar degeneration with TDP-43-positive inclusions: clinicopathologic report of 6 cases. J Neuropathol Exp Neurol. 2014 May; 73(5):467-73.J Neuropathol Exp Neurol2014-05-01T00:00:002014A novel GRN mutation (GRN c.708+6_+9delTGAG) in frontotemporal lobar degeneration with TDP-43-positive inclusions: clinicopathologic report of 6 cases.Authorship 2263019Authorship 2118947Authorship 7270234Authorship 7261559Authorship 7271722Authorship 726037924806163Krishnamoorthy KS, Eichler F, Rapalino O, Frosch MPThe New England journal of medicineCase records of the Massachusetts General Hospital. Case 14-2014. An 11-month-old girl with developmental delay. N Engl J Med. 2014 May 08; 370(19):1830-41.N Engl J Med2014-05-08T00:00:002014Case records of the Massachusetts General Hospital. Case 14-2014. An 11-month-old girl with developmental delay.24706009Landau SM, Frosch MPNeurologyTracking the earliest pathologic changes in Alzheimer disease. Neurology. 2014 May 06; 82(18):1576-7.Neurology2014-04-04T00:00:002014Tracking the earliest pathologic changes in Alzheimer disease.24573903Nuytemans K, Inchausti V, Beecham GW, Wang L, Dickson DW, Trojanowski JQ, Lee VM, Mash DC, Frosch MP, Foroud TM, Honig LS, Montine TJ, Dawson TM, Martin ER, Scott WK, Vance JMMovement disorders : official journal of the Movement Disorder SocietyAbsence of C9ORF72 expanded or intermediate repeats in autopsy-confirmed Parkinson's disease. Mov Disord. 2014 May; 29(6):827-30.Mov Disord2014-02-26T00:00:002014Absence of C9ORF72 expanded or intermediate repeats in autopsy-confirmed Parkinson's disease.Authorship 2322715Authorship 3594646Authorship 372255Authorship 2604751Authorship 734613724909198Lanthier S, Calabrese LH, Ferro JM, Putaala J, Strbian D, Chagnon M, Frosch MP, Singhal AB, Salvarani C, Létourneau-Guillon L, Poppe AY, Guilbert F, Raymond J, Muccilli AInternational journal of stroke : official journal of the International Stroke SocietyThe INTERnational Study on Primary Angiitis of the CEntral nervous system--a call to the world. Int J Stroke. 2014 Jul; 9(5):E23.Int J Stroke2014-07-01T00:00:002014The INTERnational Study on Primary Angiitis of the CEntral nervous system--a call to the world.Authorship 2463132Authorship 2889744Authorship 741484425006723Venna N, Niles JL, Lev MH, Frosch MPThe New England journal of medicineCase records of the Massachusetts General Hospital. Case 21-2014. A 68-year-old man with a sudden onset of diplopia. N Engl J Med. 2014 Jul 10; 371(2):162-73.N Engl J Med2014-07-10T00:00:002014Case records of the Massachusetts General Hospital. Case 21-2014. A 68-year-old man with a sudden onset of diplopia.Authorship 3154177Authorship 3922687Authorship 521257Authorship 7548532525188341Beecham GW, Hamilton K, Naj AC, Martin ER, Huentelman M, Myers AJ, Corneveaux JJ, Hardy J, Vonsattel JP, Younkin SG, Bennett DA, De Jager PL, Larson EB, Crane PK, Kamboh MI, Kofler JK, Mash DC, Duque L, Gilbert JR, Gwirtsman H, Buxbaum JD, Kramer P, Dickson DW, Farrer LA, Frosch MP, Ghetti B, Haines JL, Hyman BT, Kukull WA, Mayeux RP, Pericak-Vance MA, Schneider JA, Trojanowski JQ, Reiman EM, Schellenberg GD, Montine TJPLoS geneticsGenome-wide association meta-analysis of neuropathologic features of Alzheimer's disease and related dementias. PLoS Genet. 2014 Sep; 10(9):e1004606.PLoS Genet2014-09-04T00:00:002014Genome-wide association meta-analysis of neuropathologic features of Alzheimer's disease and related dementias.Authorship 5356213Authorship 2108042Authorship 3689812Authorship 3966779Authorship 4006022Authorship 763876825154857Augustinack JC, van der Kouwe AJ, Salat DH, Benner T, Stevens AA, Annese J, Fischl B, Frosch MP, Corkin SHippocampusH.M.'s contributions to neuroscience: a review and autopsy studies. Hippocampus. 2014 Nov; 24(11):1267-86.Hippocampus2014-09-23T00:00:002014H.M.'s contributions to neuroscience: a review and autopsy studies.Authorship 758889Authorship 7690138825199842Naj AC, Jun G, Reitz C, Kunkle BW, Perry W, Park YS, Beecham GW, Rajbhandary RA, Hamilton-Nelson KL, Wang LS, Kauwe JS, Huentelman MJ, Myers AJ, Bird TD, Boeve BF, Baldwin CT, Jarvik GP, Crane PK, Rogaeva E, Barmada MM, Demirci FY, Cruchaga C, Kramer PL, Ertekin-Taner N, Hardy J, Graff-Radford NR, Green RC, Larson EB, St George-Hyslop PH, Buxbaum JD, Evans DA, Schneider JA, Lunetta KL, Kamboh MI, Saykin AJ, Reiman EM, De Jager PL, Bennett DA, Morris JC, Montine TJ, Goate AM, Blacker D, Tsuang DW, Hakonarson H, Kukull WA, Foroud TM, Martin ER, Haines JL, Mayeux RP, Farrer LA, Schellenberg GD, Pericak-Vance MA, Albert MS, Albin RL, Apostolova LG, Arnold SE, Barber R, Barnes LL, Beach TG, Becker JT, Beekly D, Bigio EH, Bowen JD, Boxer A, Burke JR, Cairns NJ, Cantwell LB, Cao C, Carlson CS, Carney RM, Carrasquillo MM, Carroll SL, Chui HC, Clark DG, Corneveaux J, Cribbs DH, Crocco EA, DeCarli C, DeKosky ST, Dick M, Dickson DW, Duara R, Faber KM, Fallon KB, Farlow MR, Ferris S, Frosch MP, Galasko DR, Ganguli M, Gearing M, Geschwind DH, Ghetti B, Gilbert JR, Glass JD, Growdon JH, Hamilton RL, Harrell LE, Head E, Honig LS, Hulette CM, Hyman BT, Jicha GA, Jin LW, Karydas A, Kaye JA, Kim R, Koo EH, Kowall NW, Kramer JH, LaFerla FM, Lah JJ, Leverenz JB, Levey AI, Li G, Lieberman AP, Lin CF, Lopez OL, Lyketsos CG, Mack WJ, Martiniuk F, Mash DC, Masliah E, McCormick WC, McCurry SM, McDavid AN, McKee AC, Mesulam M, Miller BL, Miller CA, Miller JW, Murrell JR, Olichney JM, Pankratz VS, Parisi JE, Paulson HL, Peskind E, Petersen RC, Pierce A, Poon WW, Potter H, Quinn JF, Raj A, Raskind M, Reisberg B, Ringman JM, Roberson ED, Rosen HJ, Rosenberg RN, Sano M, Schneider LS, Seeley WW, Smith AG, Sonnen JA, Spina S, Stern RA, Tanzi RE, Thornton-Wells TA, Trojanowski JQ, Troncoso JC, Valladares O, Van Deerlin VM, Van Eldik LJ, Vardarajan BN, Vinters HV, Vonsattel JP, Weintraub S, Welsh-Bohmer KA, Williamson J, Wishnek S, Woltjer RL, Wright CB, Younkin SG, Yu CE, Yu LJAMA neurologyEffects of multiple genetic loci on age at onset in late-onset Alzheimer disease: a genome-wide association study. JAMA Neurol. 2014 Nov; 71(11):1394-404.JAMA Neurol2014-11-01T00:00:002014Effects of multiple genetic loci on age at onset in late-onset Alzheimer disease: a genome-wide association study.Authorship 2464232Authorship 3678553Authorship 5038832Authorship 378533625381879Butovsky O, Jedrychowski MP, Cialic R, Krasemann S, Murugaiyan G, Fanek Z, Greco DJ, Wu PM, Doykan CE, Kiner O, Lawson RJ, Frosch MP, Pochet N, Fatimy RE, Krichevsky AM, Gygi SP, Lassmann H, Berry J, Cudkowicz ME, Weiner HLAnnals of neurologyTargeting miR-155 restores abnormal microglia and attenuates disease in SOD1 mice. Ann Neurol. 2015 Jan; 77(1):75-99.Ann Neurol2014-11-27T00:00:002014Targeting miR-155 restores abnormal microglia and attenuates disease in SOD1 mice.Authorship 521044725621865Etherton MR, Neagu MR, Oakley DH, Koch MJ, Shin JH, Frosch MP, Berkowitz AL, Dietrich JJAMA neurologyA 20-year-old man with back pain and lower extremity weakness. JAMA Neurol. 2015 Mar; 72(3):363-6.JAMA Neurol2015-03-01T00:00:002015A 20-year-old man with back pain and lower extremity weakness.Authorship 2636356Authorship 3058414Authorship 3161283Authorship 322313525741528Magnain C, Augustinack JC, Konukoglu E, Frosch MP, Sakadžic S, Varjabedian A, Garcia N, Wedeen VJ, Boas DA, Fischl BNeurophotonicsOptical coherence tomography visualizes neurons in human entorhinal cortex. 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Acta Neuropathol Commun. 2014 Oct 21; 2:146.Acta Neuropathol Commun2014-10-21T00:00:002014Frequent and symmetric deposition of misfolded tau oligomers within presynaptic and postsynaptic terminals in Alzheimer's disease.25936807Iglesias JE, Augustinack JC, Nguyen K, Player CM, Player A, Wright M, Roy N, Frosch MP, McKee AC, Wald LL, Fischl B, Van Leemput KNeuroImageA computational atlas of the hippocampal formation using ex vivo, ultra-high resolution MRI: Application to adaptive segmentation of in vivo MRI. Neuroimage. 2015 Jul 15; 115:117-37.Neuroimage2015-04-29T00:00:002015A computational atlas of the hippocampal formation using ex vivo, ultra-high resolution MRI: Application to adaptive segmentation of in vivo MRI.25663231Beecham GW, Dickson DW, Scott WK, Martin ER, Schellenberg G, Nuytemans K, Larson EB, Buxbaum JD, Trojanowski JQ, Van Deerlin VM, Hurtig HI, Mash DC, Beach TG, Troncoso JC, Pletnikova O, Frosch MP, Ghetti B, Foroud TM, Honig LS, Marder K, Vonsattel JP, Goldman SM, Vinters HV, Ross OA, Wszolek ZK, Wang L, Dykxhoorn DM, Pericak-Vance MA, Montine TJ, Leverenz JB, Dawson TM, Vance JMNeurologyPARK10 is a major locus for sporadic neuropathologically confirmed Parkinson disease. Neurology. 2015 Mar 10; 84(10):972-80.Neurology2015-02-06T00:00:002015PARK10 is a major locus for sporadic neuropathologically confirmed Parkinson disease.25531812Wang LS, Naj AC, Graham RR, Crane PK, Kunkle BW, Cruchaga C, Murcia JD, Cannon-Albright L, Baldwin CT, Zetterberg H, Blennow K, Kukull WA, Faber KM, Schupf N, Norton MC, Tschanz JT, Munger RG, Corcoran CD, Rogaeva E, Lin CF, Dombroski BA, Cantwell LB, Partch A, Valladares O, Hakonarson H, St George-Hyslop P, Green RC, Goate AM, Foroud TM, Carney RM, Larson EB, Behrens TW, Kauwe JS, Haines JL, Farrer LA, Pericak-Vance MA, Mayeux R, Schellenberg GD, Albert MS, Albin RL, Apostolova LG, Arnold SE, Barber R, Barmada M, Barnes LL, Beach TG, Becker JT, Beecham GW, Beekly D, Bennett DA, Bigio EH, Bird TD, Blacker D, Boeve BF, Bowen JD, Boxer A, Burke JR, Buxbaum JD, Cairns NJ, Cao C, Carlson CS, Carroll SL, Chui HC, Clark DG, Cribbs DH, Crocco EA, DeCarli C, DeKosky ST, Demirci FY, Dick M, Dickson DW, Duara R, Ertekin-Taner N, Fallon KB, Farlow MR, Ferris S, Frosch MP, Galasko DR, Ganguli M, Gearing M, Geschwind DH, Ghetti B, Gilbert JR, Glass JD, Graff-Radford NR, Growdon JH, Hamilton RL, Hamilton-Nelson KL, Harrell LE, Head E, Honig LS, Hulette CM, Hyman BT, Jarvik GP, Jicha GA, Jin LW, Jun G, Jun G, Kamboh MI, Karydas A, Kaye JA, Kim R, Koo EH, Kowall NW, Kramer JH, LaFerla FM, Lah JJ, Leverenz JB, Levey AI, Li G, Lieberman AP, Lopez OL, Lunetta KL, Lyketsos CG, Mack WJ, Marson DC, Martin ER, Martiniuk F, Mash DC, Masliah E, McCormick WC, McCurry SM, McDavid AN, McKee AC, Mesulam WM, Miller BL, Miller CA, Miller JW, Montine TJ, Morris JC, Murrell JR, Olichney JM, Parisi JE, Perry W, Peskind E, Petersen RC, Pierce A, Poon WW, Potter H, Quinn JF, Raj A, Raskind M, Reiman EM, Reisberg B, Reitz C, Ringman JM, Roberson ED, Rosen HJ, Rosenberg RN, Sano M, Saykin AJ, Schneider JA, Schneider LS, Seeley WW, Smith AG, Sonnen JA, Spina S, Stern RA, Tanzi RE, Thornton-Wells TA, Trojanowski JQ, Troncoso JC, Tsuang DW, Van Deerlin VM, Van Eldik LJ, Vardarajan BN, Vinters HV, Vonsattel JP, Weintraub S, Welsh-Bohmer KA, Williamson J, Wishnek S, Woltjer RL, Wright CB, Younkin SG, Yu CE, Yu LJAMA neurologyRarity of the Alzheimer disease-protective APP A673T variant in the United States. 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Am J Pathol. 2016 Feb; 186(2):375-84.Am J Pathol2015-12-11T00:00:002015Plaque-Associated Local Toxicity Increases over the Clinical Course of Alzheimer Disease.Authorship 8654513Authorship 8622297Authorship 86524080Authorship 8706811026327235Montine TJ, Monsell SE, Beach TG, Bigio EH, Bu Y, Cairns NJ, Frosch M, Henriksen J, Kofler J, Kukull WA, Lee EB, Nelson PT, Schantz AM, Schneider JA, Sonnen JA, Trojanowski JQ, Vinters HV, Zhou XH, Hyman BTAlzheimer's & dementia : the journal of the Alzheimer's AssociationMultisite assessment of NIA-AA guidelines for the neuropathologic evaluation of Alzheimer's disease. 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J Clin Microbiol. 1997 Dec; 35(12):3058-61.J Clin Microbiol1997-12-01T00:00:001997Use of serum-specific immunoglobulins A and G for detection of Helicobacter pylori infection in patients with chronic gastritis by immunoblot analysis.26720093Auriel E, Charidimou A, Gurol ME, Ni J, Van Etten ES, Martinez-Ramirez S, Boulouis G, Piazza F, DiFrancesco JC, Frosch MP, Pontes-Neto OV, Shoamanesh A, Reijmer Y, Vashkevich A, Ayres AM, Schwab KM, Viswanathan A, Greenberg SMJAMA neurologyValidation of Clinicoradiological Criteria for the Diagnosis of Cerebral Amyloid Angiopathy-Related Inflammation. 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Lancet. 2016 Aug 27; 388(10047):847-9.Lancet2016-06-29T00:00:002016Zika and histopathology in first trimester infections.27351289Takeda S, Commins C, DeVos SL, Nobuhara CK, Wegmann S, Roe AD, Costantino I, Fan Z, Nicholls SB, Sherman AE, Trisini Lipsanopoulos AT, Scherzer CR, Carlson GA, Pitstick R, Peskind ER, Raskind MA, Li G, Montine TJ, Frosch MP, Hyman BTAnnals of neurologySeed-competent high-molecular-weight tau species accumulates in the cerebrospinal fluid of Alzheimer's disease mouse model and human patients. 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Nature. 2016 11 10; 539(7628):309-313.Nature2016-11-02T00:00:002016Single-cell RNA-seq supports a developmental hierarchy in human oligodendroglioma.Authorship 92280511Authorship 92274910Authorship 9208363Authorship 92460320Authorship 9246317Authorship 926997427769649Hopfner F, Haubenberger D, Galpern WR, Gwinn K, Van't Veer A, White S, Bhatia K, Adler CH, Eidelberg D, Ondo W, Stebbins GT, Tanner CM, Helmich RC, Lenz FA, Sillitoe RV, Vaillancourt D, Vitek JL, Louis ED, Shill HA, Frosch MP, Foroud T, Kuhlenbäumer G, Singleton A, Testa CM, Hallett M, Elble R, Deuschl GParkinsonism & related disordersKnowledge gaps and research recommendations for essential tremor. 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Ann Rheum Dis. 2003 Mar; 62(3):236-41.Ann Rheum Dis2003-03-01T00:00:002003Myeloid related protein 8 and 14 secretion reflects phagocyte activation and correlates with disease activity in juvenile idiopathic arthritis treated with autologous stem cell transplantation.27613583Lauer A, van Veluw SJ, William CM, Charidimou A, Roongpiboonsopit D, Vashkevich A, Ayres A, Martinez-Ramirez S, Gurol EM, Biessels GJ, Frosch M, Greenberg SM, Viswanathan ANeurologyMicrobleeds on MRI are associated with microinfarcts on autopsy in cerebral amyloid angiopathy. 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Acta Neuropathol. 2017 03; 133(3):409-415.Acta Neuropathol2016-10-22T00:00:002016Reduced vascular amyloid burden at microhemorrhage sites in cerebral amyloid angiopathy.Authorship 5294834Authorship 53764810Authorship 93641112Authorship 9335305Authorship 9339792827842190Mitchell SB, Lucente D, Larvie M, Cobos MI, Frosch M, Dickerson BCJAMA neurologyA 63-Year-Old Man With Progressive Visual Symptoms. JAMA Neurol. 2017 Jan 01; 74(1):114-118.JAMA Neurol2017-01-01T00:00:002017A 63-Year-Old Man With Progressive Visual Symptoms.27858710Sellal F, Wallon D, Martinez-Almoyna L, Marelli C, Dhar A, Oesterlé H, Rovelet-Lecrux A, Rousseau S, Kourkoulis CE, Rosand J, DiPucchio ZY, Frosch M, Gombert C, Audoin B, Miné M, Riant F, Frebourg T, Hannequin D, Campion D, Greenberg SM, Tournier-Lasserve E, Nicolas GJournal of Alzheimer's disease : JADAPP Mutations in Cerebral Amyloid Angiopathy with or without Cortical Calcifications: Report of Three Families and a Literature Review. 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