Scammell, Thomas
completed student projects: Does REM Sleep Influence Cataplexy?
completed student projects: Circadian Rhythms in Mice with Genetic Ablation of the Orexin Neurons
current student opportunities: Neurobiology of narcolepsy
eCommons Login: TES1
first name: Thomas
last name: Scammell
coauthor of: Saper, Clifford
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Narcolepsy caused by acute disseminated encephalomyelitis.
PubMed Identifier: 15148155
author list: Gledhill RF, Bartel PR, Yoshida Y, Nishino S, Scammell TE
published in: Archives of neurology
information resource reference: Narcolepsy caused by acute disseminated encephalomyelitis. Arch Neurol. 2004 May; 61(5):758-60.
journal title abbreviation: Arch Neurol
publication date: 2004-05-01T00:00:00
year: 2004
type: Academic Article
type: Article
type: Document
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Wakefulness: an eye-opening perspective on orexin neurons.
PubMed Identifier: 11591333
author list: Scammell TE
published in: Current biology : CB
information resource reference: Wakefulness: an eye-opening perspective on orexin neurons. Curr Biol. 2001 Oct 02; 11(19):R769-71.
journal title abbreviation: Curr Biol
publication date: 2001-10-02T00:00:00
year: 2001
type: Academic Article
type: Article
type: Document
type: Information Resource

Orexin/Hypocretin: wired for wakefulness.
PubMed Identifier: 12867050
author list: Mochizuki T, Scammell TE
published in: Current biology : CB
information resource reference: Orexin/Hypocretin: wired for wakefulness. Curr Biol. 2003 Jul 15; 13(14):R563-4.
journal title abbreviation: Curr Biol
publication date: 2003-07-15T00:00:00
year: 2003
type: Academic Article
type: Article
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Orexin-immunoreactive inputs to rat sympathetic preganglionic neurons.
PubMed Identifier: 14583395
author list: Llewellyn-Smith IJ, Martin CL, Marcus JN, Yanagisawa M, Minson JB, Scammell TE
published in: Neuroscience letters
information resource reference: Orexin-immunoreactive inputs to rat sympathetic preganglionic neurons. Neurosci Lett. 2003 Nov 13; 351(2):115-9.
journal title abbreviation: Neurosci Lett
publication date: 2003-11-13T00:00:00
year: 2003
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 102243
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author rank in publication: 2
linked author: Scammell, Thomas
linked information resource: Narcolepsy: neural mechanisms of sleepiness and cataplexy.

Hypothalamic regulation of sleep and circadian rhythms.
PubMed Identifier: 16251950
author list: Saper CB, Scammell TE, Lu J
published in: Nature
information resource reference: Hypothalamic regulation of sleep and circadian rhythms. Nature. 2005 Oct 27; 437(7063):1257-63.
journal title abbreviation: Nature
publication date: 2005-10-27T00:00:00
year: 2005
type: Academic Article
type: Article
type: Document
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Reward-seeking behavior in human narcolepsy.
PubMed Identifier: 21677900
author list: Dimitrova A, Fronczek R, Van der Ploeg J, Scammell T, Gautam S, Pascual-Leone A, Lammers GJ
published in: Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine
information resource reference: Reward-seeking behavior in human narcolepsy. J Clin Sleep Med. 2011 Jun 15; 7(3):293-300.
journal title abbreviation: J Clin Sleep Med
publication date: 2011-06-15T00:00:00
year: 2011
type: Academic Article
type: Article
type: Document
type: Information Resource

Hypocretin/orexin and sleep: implications for the pathophysiology and diagnosis of narcolepsy.
PubMed Identifier: 12447114
author list: Overeem S, Scammell TE, Lammers GJ
published in: Current opinion in neurology
information resource reference: Hypocretin/orexin and sleep: implications for the pathophysiology and diagnosis of narcolepsy. Curr Opin Neurol. 2002 Dec; 15(6):739-45.
journal title abbreviation: Curr Opin Neurol
publication date: 2002-12-01T00:00:00
year: 2002
type: Academic Article
type: Article
type: Document
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Regulation of daily locomotor activity and sleep by hypothalamic EGF receptor signalling.
PubMed Identifier: 14712926
author list: Kramer A, Yang FC, Snodgrass P, Li X, Scammell TE, Davis FC, Weitz CJ
published in: Novartis Foundation symposium
information resource reference: Regulation of daily locomotor activity and sleep by hypothalamic EGF receptor signalling. Novartis Found Symp. 2003; 253:250-62; discussion 102-9, 263-6, 281-4.
journal title abbreviation: Novartis Found Symp
publication date: 2003-01-01T00:00:00
year: 2003
type: Academic Article
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Orexin receptor 2 expression in the posterior hypothalamus rescues sleepiness in narcoleptic mice.
PubMed Identifier: 21368172
author list: Mochizuki T, Arrigoni E, Marcus JN, Clark EL, Yamamoto M, Honer M, Borroni E, Lowell BB, Elmquist JK, Scammell TE
published in: Proceedings of the National Academy of Sciences of the United States of America
information resource reference: Orexin receptor 2 expression in the posterior hypothalamus rescues sleepiness in narcoleptic mice. Proc Natl Acad Sci U S A. 2011 Mar 15; 108(11):4471-6.
journal title abbreviation: Proc Natl Acad Sci U S A
publication date: 2011-02-28T00:00:00
year: 2011
type: Academic Article
type: Article
type: Document
type: Information Resource

Modafinil: a novel stimulant for the treatment of narcolepsy.
PubMed Identifier: 15991923
author list: Scammell TE, Matheson J
published in: Expert opinion on investigational drugs
information resource reference: Modafinil: a novel stimulant for the treatment of narcolepsy. Expert Opin Investig Drugs. 1998 Jan; 7(1):99-112.
journal title abbreviation: Expert Opin Investig Drugs
publication date: 1998-01-01T00:00:00
year: 1998
type: Academic Article
type: Article
type: Document
type: Information Resource

Mathematical model of network dynamics governing mouse sleep-wake behavior.
PubMed Identifier: 17409167
author list: Behn CG, Brown EN, Scammell TE, Kopell NJ
published in: Journal of neurophysiology
information resource reference: Mathematical model of network dynamics governing mouse sleep-wake behavior. J Neurophysiol. 2007 Jun; 97(6):3828-40.
journal title abbreviation: J Neurophysiol
publication date: 2007-04-04T00:00:00
year: 2007
type: Academic Article
type: Article
type: Document
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Silent functional magnetic resonance imaging demonstrates focal activation in rapid eye movement sleep.
PubMed Identifier: 10599807
author list: Lövblad KO, Thomas R, Jakob PM, Scammell T, Bassetti C, Griswold M, Ives J, Matheson J, Edelman RR, Warach S
published in: Neurology
information resource reference: Silent functional magnetic resonance imaging demonstrates focal activation in rapid eye movement sleep. Neurology. 1999 Dec 10; 53(9):2193-5.
journal title abbreviation: Neurology
publication date: 1999-12-10T00:00:00
year: 1999
type: Academic Article
type: Article
type: Document
type: Information Resource

Mechanisms of Cataplexy
end date: 2022-04-30
principal investigator name: SCAMMELL, THOMAS E
start date: 2018-07-01
type: Grant
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contributes to: Mechanisms of Cataplexy

Pharmacotherapy for cataplexy.
PubMed Identifier: 15336236
author list: Houghton WC, Scammell TE, Thorpy M
published in: Sleep medicine reviews
information resource reference: Pharmacotherapy for cataplexy. Sleep Med Rev. 2004 Oct; 8(5):355-66.
journal title abbreviation: Sleep Med Rev
publication date: 2004-10-01T00:00:00
year: 2004
type: Academic Article
type: Article
type: Document
type: Information Resource

Modafinil more effectively induces wakefulness in orexin-null mice than in wild-type littermates.
PubMed Identifier: 15652995
author list: Willie JT, Renthal W, Chemelli RM, Miller MS, Scammell TE, Yanagisawa M, Sinton CM
published in: Neuroscience
information resource reference: Modafinil more effectively induces wakefulness in orexin-null mice than in wild-type littermates. Neuroscience. 2005; 130(4):983-95.
journal title abbreviation: Neuroscience
publication date: 2005-01-01T00:00:00
year: 2005
type: Academic Article
type: Article
type: Document
type: Information Resource

Activation of the basal forebrain by the orexin/hypocretin neurones.
PubMed Identifier: 19723027
author list: Arrigoni E, Mochizuki T, Scammell TE
published in: Acta physiologica (Oxford, England)
information resource reference: Activation of the basal forebrain by the orexin/hypocretin neurones. Acta Physiol (Oxf). 2010 Mar; 198(3):223-35.
journal title abbreviation: Acta Physiol (Oxf)
publication date: 2009-09-01T00:00:00
year: 2009
type: Academic Article
type: Article
type: Document
type: Information Resource

Is low histamine a fundamental cause of sleepiness in narcolepsy and idiopathic hypersomnia?
PubMed Identifier: 19238797
author list: Scammell TE, Mochizuki T
published in: Sleep
information resource reference: Is low histamine a fundamental cause of sleepiness in narcolepsy and idiopathic hypersomnia? Sleep. 2009 Feb; 32(2):133-4.
journal title abbreviation: Sleep
publication date: 2009-02-01T00:00:00
year: 2009
type: Academic Article
type: Article
type: Document
type: Information Resource

Hcrtr1 and 2 signaling differentially regulates depression-like behaviors.
PubMed Identifier: 21377495
author list: Scott MM, Marcus JN, Pettersen A, Birnbaum SG, Mochizuki T, Scammell TE, Nestler EJ, Elmquist JK, Lutter M
published in: Behavioural brain research
information resource reference: Hcrtr1 and 2 signaling differentially regulates depression-like behaviors. Behav Brain Res. 2011 Sep 23; 222(2):289-94.
journal title abbreviation: Behav Brain Res
publication date: 2011-03-04T00:00:00
year: 2011
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1090209
type: Authorship
author rank in publication: 5
linked author: Scammell, Thomas
linked information resource: Melanin-concentrating hormone neurons contribute to dysregulation of rapid eye movement sleep in narcolepsy.

Melanin-concentrating hormone neurons contribute to dysregulation of rapid eye movement sleep in narcolepsy.
PubMed Identifier: 30149182
author list: Naganuma F, Bandaru SS, Absi G, Mahoney CE, Scammell TE, Vetrivelan R
published in: Neurobiology of disease
information resource reference: Melanin-concentrating hormone neurons contribute to dysregulation of rapid eye movement sleep in narcolepsy. Neurobiol Dis. 2018 12; 120:12-20.
journal title abbreviation: Neurobiol Dis
publication date: 2018-08-24T00:00:00
year: 2018
type: Academic Article
type: Article
type: Document
type: Information Resource

Narcolepsy: neural mechanisms of sleepiness and cataplexy.
PubMed Identifier: 22956821
author list: Burgess CR, Scammell TE
published in: The Journal of neuroscience : the official journal of the Society for Neuroscience
information resource reference: Narcolepsy: neural mechanisms of sleepiness and cataplexy. J Neurosci. 2012 Sep 05; 32(36):12305-11.
journal title abbreviation: J Neurosci
publication date: 2012-09-05T00:00:00
year: 2012
type: Academic Article
type: Article
type: Document
type: Information Resource

Delayed orexin signaling consolidates wakefulness and sleep: physiology and modeling.
PubMed Identifier: 18417630
author list: Diniz Behn CG, Kopell N, Brown EN, Mochizuki T, Scammell TE
published in: Journal of neurophysiology
information resource reference: Delayed orexin signaling consolidates wakefulness and sleep: physiology and modeling. J Neurophysiol. 2008 Jun; 99(6):3090-103.
journal title abbreviation: J Neurophysiol
publication date: 2008-04-16T00:00:00
year: 2008
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1092801
type: Authorship
author rank in publication: 1
linked author: Scammell, Thomas
linked information resource: Histamine: neural circuits and new medications.

Histamine: neural circuits and new medications.
PubMed Identifier: 30239935
author list: Scammell TE, Jackson AC, Franks NP, Wisden W, Dauvilliers Y
published in: Sleep
information resource reference: Histamine: neural circuits and new medications. Sleep. 2019 01 01; 42(1).
journal title abbreviation: Sleep
publication date: 2019-01-01T00:00:00
year: 2019
type: Academic Article
type: Article
type: Document
type: Information Resource

Coexistence of narcolepsy and Alzheimer's disease.
PubMed Identifier: 21257235
author list: Scammell TE, Matheson JK, Honda M, Thannickal TC, Siegel JM
published in: Neurobiology of aging
information resource reference: Coexistence of narcolepsy and Alzheimer's disease. Neurobiol Aging. 2012 Jul; 33(7):1318-9.
journal title abbreviation: Neurobiol Aging
publication date: 2011-01-22T00:00:00
year: 2011
type: Academic Article
type: Article
type: Document
type: Information Resource

Galanin neurons in the ventrolateral preoptic area promote sleep and heat loss in mice.
PubMed Identifier: 30297727
author list: Kroeger D, Absi G, Gagliardi C, Bandaru SS, Madara JC, Ferrari LL, Arrigoni E, Münzberg H, Scammell TE, Saper CB, Vetrivelan R
published in: Nature communications
information resource reference: Galanin neurons in the ventrolateral preoptic area promote sleep and heat loss in mice. Nat Commun. 2018 10 08; 9(1):4129.
journal title abbreviation: Nat Commun
publication date: 2018-10-08T00:00:00
year: 2018
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1106161
type: Authorship
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linked author: Scammell, Thomas
linked information resource: Galanin neurons in the ventrolateral preoptic area promote sleep and heat loss in mice.

Sleep neurobiology for the clinician.
PubMed Identifier: 15283019
author list: España RA, Scammell TE
published in: Sleep
information resource reference: Sleep neurobiology for the clinician. Sleep. 2004 Jun 15; 27(4):811-20.
journal title abbreviation: Sleep
publication date: 2004-06-15T00:00:00
year: 2004
type: Academic Article
type: Article
type: Document
type: Information Resource

Thalamic Cav3.1 T-type Ca2+ channel plays a crucial role in stabilizing sleep.
PubMed Identifier: 15677322
author list: Anderson MP, Mochizuki T, Xie J, Fischler W, Manger JP, Talley EM, Scammell TE, Tonegawa S
published in: Proceedings of the National Academy of Sciences of the United States of America
information resource reference: Thalamic Cav3.1 T-type Ca2+ channel plays a crucial role in stabilizing sleep. Proc Natl Acad Sci U S A. 2005 Feb 01; 102(5):1743-8.
journal title abbreviation: Proc Natl Acad Sci U S A
publication date: 2005-01-26T00:00:00
year: 2005
type: Academic Article
type: Article
type: Document
type: Information Resource

No evidence for a circadian rhythm of protein synthesis in the rat suprachiasmatic nuclei.
PubMed Identifier: 2765915
author list: Scammell TE, Schwartz WJ, Smith CB
published in: Brain research
information resource reference: No evidence for a circadian rhythm of protein synthesis in the rat suprachiasmatic nuclei. Brain Res. 1989 Aug 07; 494(1):155-8.
journal title abbreviation: Brain Res
publication date: 1989-08-07T00:00:00
year: 1989
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1119851
type: Authorship
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linked author: Scammell, Thomas
linked information resource: The neurobiological basis of narcolepsy.

The neurobiological basis of narcolepsy.
PubMed Identifier: 30546103
author list: Mahoney CE, Cogswell A, Koralnik IJ, Scammell TE
published in: Nature reviews. Neuroscience
information resource reference: The neurobiological basis of narcolepsy. Nat Rev Neurosci. 2019 02; 20(2):83-93.
journal title abbreviation: Nat Rev Neurosci
publication date: 2019-02-01T00:00:00
year: 2019
type: Academic Article
type: Article
type: Document
type: Information Resource

The neurobiology, diagnosis, and treatment of narcolepsy.
PubMed Identifier: 12557281
author list: Scammell TE
published in: Annals of neurology
information resource reference: The neurobiology, diagnosis, and treatment of narcolepsy. Ann Neurol. 2003 Feb; 53(2):154-66.
journal title abbreviation: Ann Neurol
publication date: 2003-02-01T00:00:00
year: 2003
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1126627
type: Authorship
author rank in publication: 3
linked author: Scammell, Thomas
linked information resource: Basal forebrain subcortical projections.

Basal forebrain subcortical projections.
PubMed Identifier: 30612231
author list: Agostinelli LJ, Geerling JC, Scammell TE
published in: Brain structure & function
information resource reference: Basal forebrain subcortical projections. Brain Struct Funct. 2019 Apr; 224(3):1097-1117.
journal title abbreviation: Brain Struct Funct
publication date: 2019-01-05T00:00:00
year: 2019
type: Academic Article
type: Article
type: Document
type: Information Resource

The trouble with Tribbles: do antibodies against TRIB2 cause narcolepsy?
PubMed Identifier: 20614841
author list: Lim AS, Scammell TE
published in: Sleep
information resource reference: The trouble with Tribbles: do antibodies against TRIB2 cause narcolepsy? Sleep. 2010 Jul; 33(7):857-8.
journal title abbreviation: Sleep
publication date: 2010-07-01T00:00:00
year: 2010
type: Academic Article
type: Article
type: Document
type: Information Resource

Sleep state switching.
PubMed Identifier: 21172606
author list: Saper CB, Fuller PM, Pedersen NP, Lu J, Scammell TE
published in: Neuron
information resource reference: Sleep state switching. Neuron. 2010 Dec 22; 68(6):1023-42.
journal title abbreviation: Neuron
publication date: 2010-12-22T00:00:00
year: 2010
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1131407
type: Authorship
author rank in publication: 21
linked author: Scammell, Thomas
linked information resource: Sleep modulates haematopoiesis and protects against atherosclerosis.

Sleep modulates haematopoiesis and protects against atherosclerosis.
PubMed Identifier: 30760925
author list: McAlpine CS, Kiss MG, Rattik S, He S, Vassalli A, Valet C, Anzai A, Chan CT, Mindur JE, Kahles F, Poller WC, Frodermann V, Fenn AM, Gregory AF, Halle L, Iwamoto Y, Hoyer FF, Binder CJ, Libby P, Tafti M, Scammell TE, Nahrendorf M, Swirski FK
published in: Nature
information resource reference: Sleep modulates haematopoiesis and protects against atherosclerosis. Nature. 2019 02; 566(7744):383-387.
journal title abbreviation: Nature
publication date: 2019-02-13T00:00:00
year: 2019
type: Academic Article
type: Article
type: Document
type: Information Resource

Intracellular Signaling Peptides and Proteins
MeSH DescriptorUI: D047908
MeSH semantic group name: Chemicals & Drugs
number of authors: 1300
number of publications: 2935
uniqueness weight: 0.479213
type: Concept

Neuropeptides
MeSH DescriptorUI: D009479
MeSH semantic group name: Chemicals & Drugs
number of authors: 446
number of publications: 942
uniqueness weight: 0.656005
type: Concept

Narcolepsy
MeSH DescriptorUI: D009290
MeSH semantic group name: Disorders
number of authors: 77
number of publications: 212
uniqueness weight: 0.79055
type: Concept

Wakefulness
MeSH DescriptorUI: D014851
MeSH semantic group name: Physiology
number of authors: 440
number of publications: 1239
uniqueness weight: 0.598958
type: Concept

Cataplexy
MeSH DescriptorUI: D002385
MeSH semantic group name: Disorders
number of authors: 29
number of publications: 59
uniqueness weight: 0.934298
type: Concept

Medicine
type: Department
type: Organization

Neurology
type: Department
type: Organization

Psychiatry
type: Department
type: Organization

Sleep Medicine
type: Division
type: Organization

Beth Israel Deaconess Medical Center
type: Organization

Brigham and Women's Hospital
type: Organization

Boston Children's Hospital
type: Organization

Maski, Kiran
eCommons Login: KP59
first name: Kiran
last name: Maski
full name: Kiran Prasad Maski, M.D.
has faculty rank: Associate Professor
latitude: 42.33743600000000
longitude: -71.10544700000000
Person ID: 64551
person in primary position: Associate Professor of Neurology
type: Agent
type: Person
preferred title: Associate Professor of Neurology

Saper, Clifford
eCommons Login: CBS2
first name: Clifford
last name: Saper
full name: Clifford B. Saper, M.D.,Ph.D.
has faculty rank: Full Professor
latitude: 42.34022770000000
longitude: -71.10585400000000
photo: https://connects.catalyst.harvard.edu/Profiles/profile/Modules/CustomViewPersonGeneralInfo/PhotoHandler.ashx
Person ID: 17796
person in primary position: James Jackson Putnam Professor of Neurology
type: Agent
type: Person
preferred title: James Jackson Putnam Professor of Neurology

Czeisler, Charles
eCommons Login: CAC5
first name: Charles
last name: Czeisler
full name: Charles Andrew Czeisler, M.D., Ph.D.
has faculty rank: Full Professor
latitude: 42.33710500000000
longitude: -71.10231700000000
photo: https://connects.catalyst.harvard.edu/Profiles/profile/Modules/CustomViewPersonGeneralInfo/PhotoHandler.ashx
Person ID: 24237
person in primary position: Frank Baldino, Jr., Ph.D. Professor of Sleep Medicine
type: Agent
type: Person
preferred title: Frank Baldino, Jr., Ph.D. Professor of Sleep Medicine

Arrigoni, Elda
eCommons Login: EA10
first name: Elda
last name: Arrigoni
full name: Elda Arrigoni, Ph.D.
has faculty rank: Associate Professor
latitude: 42.33849900000000
longitude: -71.10446000000000
Person ID: 41974
person in primary position: Associate Professor of Neurology
type: Agent
type: Person
preferred title: Associate Professor of Neurology

Redline, Susan
eCommons Login: SR165
first name: Susan
last name: Redline
full name: Susan Redline, M.D.
has faculty rank: Full Professor
latitude: 42.33710500000000
longitude: -71.10231700000000
Person ID: 27634
person in primary position: Peter C. Farrell Professor of Sleep Medicine
type: Agent
type: Person
preferred title: Peter C. Farrell Professor of Sleep Medicine

selected publications
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predicate: selected publications
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research areas
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similar to
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predicate: similar to
type: Network

Stickgold, Robert
eCommons Login: RAS1
first name: Robert
last name: Stickgold
full name: Robert Stickgold, Ph.D.
has faculty rank: Full Professor
latitude: 42.34022770000000
longitude: -71.10585400000000
Person ID: 31708
person in primary position: Professor of Psychiatry
type: Agent
type: Person
preferred title: Professor of Psychiatry

Authorship 1175383
type: Authorship
author rank in publication: 17
linked author: Scammell, Thomas
linked information resource: Narcolepsy - clinical spectrum, aetiopathophysiology, diagnosis and treatment.

Narcolepsy - clinical spectrum, aetiopathophysiology, diagnosis and treatment.
PubMed Identifier: 31324898
author list: Bassetti CLA, Adamantidis A, Burdakov D, Han F, Gay S, Kallweit U, Khatami R, Koning F, Kornum BR, Lammers GJ, Liblau RS, Luppi PH, Mayer G, Pollmächer T, Sakurai T, Sallusto F, Scammell TE, Tafti M, Dauvilliers Y
published in: Nature reviews. Neurology
information resource reference: Narcolepsy - clinical spectrum, aetiopathophysiology, diagnosis and treatment. Nat Rev Neurol. 2019 09; 15(9):519-539.
journal title abbreviation: Nat Rev Neurol
publication date: 2019-07-19T00:00:00
year: 2019
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1183549
type: Authorship
author rank in publication: 2
linked author: Scammell, Thomas
linked information resource: Regulation of hippocampal dendritic spines following sleep deprivation.

Regulation of hippocampal dendritic spines following sleep deprivation.
PubMed Identifier: 31454077
author list: Gisabella B, Scammell T, Bandaru SS, Saper CB
published in: The Journal of comparative neurology
information resource reference: Regulation of hippocampal dendritic spines following sleep deprivation. J Comp Neurol. 2020 02 15; 528(3):380-388.
journal title abbreviation: J Comp Neurol
publication date: 2019-09-09T00:00:00
year: 2019
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1193096
type: Authorship
author rank in publication: 5
linked author: Scammell, Thomas
linked information resource: Reassessing the Role of Histaminergic Tuberomammillary Neurons in Arousal Control.

Reassessing the Role of Histaminergic Tuberomammillary Neurons in Arousal Control.
PubMed Identifier: 31548232
author list: Venner A, Mochizuki T, De Luca R, Anaclet C, Scammell TE, Saper CB, Arrigoni E, Fuller PM
published in: The Journal of neuroscience : the official journal of the Society for Neuroscience
information resource reference: Reassessing the Role of Histaminergic Tuberomammillary Neurons in Arousal Control. J Neurosci. 2019 11 06; 39(45):8929-8939.
journal title abbreviation: J Neurosci
publication date: 2019-09-23T00:00:00
year: 2019
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 145284
type: Authorship
author rank in publication: 5
linked author: Scammell, Thomas
linked information resource: Abnormal sleep/wake dynamics in orexin knockout mice.

Authorship 1202506
type: Authorship
author rank in publication: 6
linked author: Scammell, Thomas
linked information resource: Critical Dynamics and Coupling in Bursts of Cortical Rhythms Indicate Non-Homeostatic Mechanism for Sleep-Stage Transitions and Dual Role of VLPO Neurons in Both Sleep and Wake.

Critical Dynamics and Coupling in Bursts of Cortical Rhythms Indicate Non-Homeostatic Mechanism for Sleep-Stage Transitions and Dual Role of VLPO Neurons in Both Sleep and Wake.
PubMed Identifier: 31694962
author list: Lombardi F, Gómez-Extremera M, Bernaola-Galván P, Vetrivelan R, Saper CB, Scammell TE, Ivanov PC
published in: The Journal of neuroscience : the official journal of the Society for Neuroscience
information resource reference: Critical Dynamics and Coupling in Bursts of Cortical Rhythms Indicate Non-Homeostatic Mechanism for Sleep-Stage Transitions and Dual Role of VLPO Neurons in Both Sleep and Wake. J Neurosci. 2020 01 02; 40(1):171-190.
journal title abbreviation: J Neurosci
publication date: 2019-11-06T00:00:00
year: 2019
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1203984
type: Authorship
author rank in publication: 3
linked author: Scammell, Thomas
linked information resource: Children with Narcolepsy type 1 have increased T-cell responses to orexins.

Children with Narcolepsy type 1 have increased T-cell responses to orexins.
PubMed Identifier: 31730293
author list: Cogswell AC, Maski K, Scammell TE, Tucker D, Orban ZS, Koralnik IJ
published in: Annals of clinical and translational neurology
information resource reference: Children with Narcolepsy type 1 have increased T-cell responses to orexins. Ann Clin Transl Neurol. 2019 12; 6(12):2566-2572.
journal title abbreviation: Ann Clin Transl Neurol
publication date: 2019-11-15T00:00:00
year: 2019
type: Academic Article
type: Article
type: Document
type: Information Resource

Instructor in Neurology
is primary position: true
position in department: Neurology
position in division: https://connects.catalyst.harvard.edu/Profiles/profile/1229413
sort order: 1
type: Position
HR job title: Instructor in Neurology
position in organization: Beth Israel Deaconess Medical Center

Professor of Psychiatry
is primary position: true
position in department: Psychiatry
position in division: https://connects.catalyst.harvard.edu/Profiles/profile/1229413
sort order: 1
type: Position
HR job title: Professor of Psychiatry
position in organization: Beth Israel Deaconess Medical Center

Professor of Neurology
is primary position: true
position in department: Neurology
position in division: https://connects.catalyst.harvard.edu/Profiles/profile/1229413
sort order: 1
type: Position
HR job title: Professor of Neurology
position in organization: Beth Israel Deaconess Medical Center

Authorship 1211668
type: Authorship
author rank in publication: 3
linked author: Scammell, Thomas
linked information resource: Dual orexin receptor antagonists increase sleep and cataplexy in wild type mice.

Dual orexin receptor antagonists increase sleep and cataplexy in wild type mice.
PubMed Identifier: 31830270
author list: Mahoney CE, Mochizuki T, Scammell TE
published in: Sleep
information resource reference: Dual orexin receptor antagonists increase sleep and cataplexy in wild type mice. Sleep. 2020 06 15; 43(6).
journal title abbreviation: Sleep
publication date: 2020-06-15T00:00:00
year: 2020
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1216904
type: Authorship
author rank in publication: 6
linked author: Scammell, Thomas
linked information resource: A circuit perspective on narcolepsy.

A circuit perspective on narcolepsy.
PubMed Identifier: 31919524
author list: Adamantidis AR, Schmidt MH, Carter ME, Burdakov D, Peyron C, Scammell TE
published in: Sleep
information resource reference: A circuit perspective on narcolepsy. Sleep. 2020 05 12; 43(5).
journal title abbreviation: Sleep
publication date: 2020-05-12T00:00:00
year: 2020
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 167994
type: Authorship
author rank in publication: 2
linked author: Scammell, Thomas
linked information resource: Sleep neurobiology for the clinician.

Authorship 164940
type: Authorship
author rank in publication: 1
linked author: Scammell, Thomas
linked information resource: Hypothalamic arousal regions are activated during modafinil-induced wakefulness.

Authorship 1237930
type: Authorship
author rank in publication: 1
linked author: Scammell, Thomas
linked information resource: Treatment of narcolepsy with natalizumab.

Authorship 1237916
type: Authorship
author rank in publication: 11
linked author: Scammell, Thomas
linked information resource: Defining disrupted nighttime sleep and assessing its diagnostic utility for pediatric narcolepsy type 1.

Treatment of narcolepsy with natalizumab.
PubMed Identifier: 32249922
author list: Scammell TE, Luo G, Borker P, Sullivan L, Biddle K, Mignot E
published in: Sleep
information resource reference: Treatment of narcolepsy with natalizumab. Sleep. 2020 07 13; 43(7).
journal title abbreviation: Sleep
publication date: 2020-07-13T00:00:00
year: 2020
type: Academic Article
type: Article
type: Document
type: Information Resource

Defining disrupted nighttime sleep and assessing its diagnostic utility for pediatric narcolepsy type 1.
PubMed Identifier: 32253429
author list: Maski K, Pizza F, Liu S, Steinhart E, Little E, Colclasure A, Diniz Behn C, Vandi S, Antelmi E, Weller E, Scammell TE, Plazzi G
published in: Sleep
information resource reference: Defining disrupted nighttime sleep and assessing its diagnostic utility for pediatric narcolepsy type 1. Sleep. 2020 10 13; 43(10).
journal title abbreviation: Sleep
publication date: 2020-10-13T00:00:00
year: 2020
type: Academic Article
type: Article
type: Document
type: Information Resource

Univ. of Rochester, Neuroscience
end date: 1984
educational organization: Univ. of Rochester
training location: Rochester, NY
type: EducationalTraining
degree earned: BS
major field of degree: Neuroscience

Univ. of Mass. Medical School, Medicine
end date: 1988
educational organization: Univ. of Mass. Medical School
training location: Worcester, MA
type: EducationalTraining
degree earned: MD
major field of degree: Medicine

Univ. of Mass. Medical Center, Medicine Resident
end date: 1990
educational organization: Univ. of Mass. Medical Center
training location: Worcester, MA
type: EducationalTraining
major field of degree: Medicine Resident

Univ. of California, Neurology Residency
end date: 1993
educational organization: Univ. of California
training location: San Francisco, CA
type: EducationalTraining
major field of degree: Neurology Residency

Center for Stress and Neural Regulation of Reproductive Aging Health Outcomes
end date: 2030-08-31
principal investigator name: JOFFE, HADINE
start date: 2020-06-01
type: Grant
sponsor award id: U54AG062322

Mechanisms of sleep and sleep apnea
end date: 2030-08-31
principal investigator name: SAPER, CLIFFORD B
start date: 2020-07-01
type: Grant
sponsor award id: P01HL149630

Authorship 1255624
type: Authorship
author rank in publication: 3
linked author: Scammell, Thomas
linked information resource: COMMENTARY on Lammers et al, Diagnosis of central disorders of hypersomnolence: Challenges in defining central disorders of hypersomnolence.

COMMENTARY on Lammers et al, Diagnosis of central disorders of hypersomnolence: Challenges in defining central disorders of hypersomnolence.
PubMed Identifier: 32554241
author list: Maski K, Mignot E, Scammell TE
published in: Sleep medicine reviews
information resource reference: COMMENTARY on Lammers et al, Diagnosis of central disorders of hypersomnolence: Challenges in defining central disorders of hypersomnolence. Sleep Med Rev. 2020 08; 52:101327.
journal title abbreviation: Sleep Med Rev
publication date: 2020-05-06T00:00:00
year: 2020
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1262481
type: Authorship
author rank in publication: 4
linked author: Scammell, Thomas
linked information resource: Input-output connections of LJA5 prodynorphin neurons.

Input-output connections of LJA5 prodynorphin neurons.
PubMed Identifier: 32602558
author list: Agostinelli LJ, Mix MR, Hefti MM, Scammell TE, Bassuk AG
published in: The Journal of comparative neurology
information resource reference: Input-output connections of LJA5 prodynorphin neurons. J Comp Neurol. 2021 02; 529(3):635-654.
journal title abbreviation: J Comp Neurol
publication date: 2020-07-24T00:00:00
year: 2020
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1323454
type: Authorship
author rank in publication: 5
linked author: Scammell, Thomas
linked information resource: Stability of nocturnal wake and sleep stages defines central nervous system disorders of hypersomnolence.

Stability of nocturnal wake and sleep stages defines central nervous system disorders of hypersomnolence.
PubMed Identifier: 33512510
author list: Maski KP, Colclasure A, Little E, Steinhart E, Scammell TE, Navidi W, Diniz Behn C
published in: Sleep
information resource reference: Stability of nocturnal wake and sleep stages defines central nervous system disorders of hypersomnolence. Sleep. 2021 07 09; 44(7).
journal title abbreviation: Sleep
publication date: 2021-07-09T00:00:00
year: 2021
type: Academic Article
type: Article
type: Document
type: Information Resource

Co-Investigator
type: Researcher Role
researcher role of: Scammell, Thomas
contributes to: Mechanisms of sleep and sleep apnea

Co-Investigator
type: Researcher Role
researcher role of: Scammell, Thomas
contributes to: Center for Stress and Neural Regulation of Reproductive Aging Health Outcomes

Authorship 1342436
type: Authorship
author rank in publication: 4
linked author: Scammell, Thomas
linked information resource: The Impacts of Age and Sex in a Mouse Model of Childhood Narcolepsy.

The Impacts of Age and Sex in a Mouse Model of Childhood Narcolepsy.
PubMed Identifier: 33746708
author list: Coffey AA, Joyal AA, Yamanaka A, Scammell TE
published in: Frontiers in neuroscience
information resource reference: The Impacts of Age and Sex in a Mouse Model of Childhood Narcolepsy. Front Neurosci. 2021; 15:644757.
journal title abbreviation: Front Neurosci
publication date: 2021-03-04T00:00:00
year: 2021
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1390288
type: Authorship
author rank in publication: 11
linked author: Scammell, Thomas
linked information resource: Orexin receptors 1 and 2 in serotonergic neurons differentially regulate peripheral glucose metabolism in obesity.

Orexin receptors 1 and 2 in serotonergic neurons differentially regulate peripheral glucose metabolism in obesity.
PubMed Identifier: 34475397
author list: Xiao X, Yeghiazaryan G, Hess S, Klemm P, Sieben A, Kleinridders A, Morgan DA, Wunderlich FT, Rahmouni K, Kong D, Scammell TE, Lowell BB, Kloppenburg P, Brüning JC, Hausen AC
published in: Nature communications
information resource reference: Orexin receptors 1 and 2 in serotonergic neurons differentially regulate peripheral glucose metabolism in obesity. Nat Commun. 2021 09 02; 12(1):5249.
journal title abbreviation: Nat Commun
publication date: 2021-09-02T00:00:00
year: 2021
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 204402
type: Authorship
author rank in publication: 3
linked author: Scammell, Thomas
linked information resource: Mistaken diagnosis of psychogenic gait disorder in a man with status cataplecticus ("limp man syndrome").

Authorship 210498
type: Authorship
author rank in publication: 4
linked author: Scammell, Thomas
linked information resource: Intravenous lipopolysaccharide induces cyclooxygenase 2-like immunoreactivity in rat brain perivascular microglia and meningeal macrophages.

Authorship 2532
type: Authorship
author rank in publication: 6
linked author: Scammell, Thomas
linked information resource: Orexin neurons are necessary for the circadian control of REM sleep.

Authorship 1438199
type: Authorship
author rank in publication: 7
linked author: Scammell, Thomas
linked information resource: Development and Validation of the Pediatric Hypersomnolence Survey.

Development and Validation of the Pediatric Hypersomnolence Survey.
PubMed Identifier: 35314496
author list: Maski K, Worhach J, Steinhart E, Boduch M, Morse AM, Strunc M, Scammell T, Owens J, Jesteadt L, Crisp C, Williams D, Sideridis G
published in: Neurology
information resource reference: Development and Validation of the Pediatric Hypersomnolence Survey. Neurology. 2022 05 10; 98(19):e1964-e1975.
journal title abbreviation: Neurology
publication date: 2022-03-21T00:00:00
year: 2022
type: Academic Article
type: Article
type: Document
type: Information Resource

Neurobiology of narcolepsy
end date: 2027-06-30T00:00:00
start date: 2025-10-01T00:00:00
type: Mentoring - Current Student Opportunity
overview: Narcolepsy is a common sleep disorder caused by loss of the orexin-producing neurons in the hypothalamus. The student will perform basic science research using mouse models of narcolepsy to identify the brain circuits that give rise to sleepiness and cataplexy. Techniques may include fiber photometry to track neuronal activity and levels of neurotransmitters, optogenetics, chemogenetics, sleep recordings in mice, and anatomic studies. Prior experience in basic animal research is helpful but not necessary. The mentor (Dr. Scammell) has an office next to the lab in the Center for Life Sciences and will meet with the student at least weekly.
webpage: https://connects.catalyst.harvard.edu/profiles/studentopportunities/Detail

Authorship 1446766
type: Authorship
author rank in publication: 9
linked author: Scammell, Thomas
linked information resource: Circadian Rhythms and Sleep Are Dependent Upon Expression Levels of Key Ubiquitin Ligase Ube3a.

Circadian Rhythms and Sleep Are Dependent Upon Expression Levels of Key Ubiquitin Ligase Ube3a.
PubMed Identifier: 35401134
author list: Shi SQ, Mahoney CE, Houdek P, Zhao W, Anderson MP, Zhuo X, Beaudet A, Sumova A, Scammell TE, Johnson CH
published in: Frontiers in behavioral neuroscience
information resource reference: Circadian Rhythms and Sleep Are Dependent Upon Expression Levels of Key Ubiquitin Ligase Ube3a. Front Behav Neurosci. 2022; 16:837523.
journal title abbreviation: Front Behav Neurosci
publication date: 2022-03-23T00:00:00
year: 2022
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1452220
type: Authorship
author rank in publication: 2
linked author: Scammell, Thomas
linked information resource: Catching Up on REMs.

Catching Up on REMs.
PubMed Identifier: 35584160
author list: Burgess CR, Scammell TE
published in: The New England journal of medicine
information resource reference: Catching Up on REMs. N Engl J Med. 2022 05 19; 386(20):1950-1952.
journal title abbreviation: N Engl J Med
publication date: 2022-05-19T00:00:00
year: 2022
type: Academic Article
type: Article
type: Document
type: Information Resource

Orexin neurons inhibit sleep to promote arousal.
PubMed Identifier: 35851580
author list: De Luca R, Nardone S, Grace KP, Venner A, Cristofolini M, Bandaru SS, Sohn LT, Kong D, Mochizuki T, Viberti B, Zhu L, Zito A, Scammell TE, Saper CB, Lowell BB, Fuller PM, Arrigoni E
published in: Nature communications
information resource reference: Orexin neurons inhibit sleep to promote arousal. Nat Commun. 2022 07 18; 13(1):4163.
journal title abbreviation: Nat Commun
publication date: 2022-07-18T00:00:00
year: 2022
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1462925
type: Authorship
author rank in publication: 13
linked author: Scammell, Thomas
linked information resource: Orexin neurons inhibit sleep to promote arousal.

Authorship 1464919
type: Authorship
author rank in publication: 1
linked author: Scammell, Thomas
linked information resource: Major advances in sleep neurology: 2002-22.

Major advances in sleep neurology: 2002-22.
PubMed Identifier: 35841898
author list: Scammell TE, Saper CB
published in: The Lancet. Neurology
information resource reference: Major advances in sleep neurology: 2002-22. Lancet Neurol. 2022 08; 21(8):678-680.
journal title abbreviation: Lancet Neurol
publication date: 2022-08-01T00:00:00
year: 2022
type: Academic Article
type: Article
type: Document
type: Information Resource

Glutamatergic pedunculopontine tegmental neurons control wakefulness and locomotion via distinct axonal projections.
PubMed Identifier: 36170177
author list: Kroeger D, Thundercliffe J, Phung A, De Luca R, Geraci C, Bragg S, McCafferty KJ, Bandaru SS, Arrigoni E, Scammell TE
published in: Sleep
information resource reference: Glutamatergic pedunculopontine tegmental neurons control wakefulness and locomotion via distinct axonal projections. Sleep. 2022 Dec 12; 45(12).
journal title abbreviation: Sleep
publication date: 2022-12-12T00:00:00
year: 2022
type: Academic Article
type: Article
type: Document
type: Information Resource

James Jackson Putnam Professor of Neurology
is primary position: true
position in department: Neurology
position in division: https://connects.catalyst.harvard.edu/Profiles/profile/1229413
sort order: 1
type: Position
HR job title: James Jackson Putnam Professor of Neurology
position in organization: Beth Israel Deaconess Medical Center

Authorship 1489280
type: Authorship
author rank in publication: 4
linked author: Scammell, Thomas
linked information resource: The impact of narcolepsy on social relationships in young adults.

Authorship 1500094
type: Authorship
author rank in publication: 10
linked author: Scammell, Thomas
linked information resource: Glutamatergic pedunculopontine tegmental neurons control wakefulness and locomotion via distinct axonal projections.

The impact of narcolepsy on social relationships in young adults.
PubMed Identifier: 35946418
author list: Davidson RD, Biddle K, Nassan M, Scammell TE, Zhou ES
published in: Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine
information resource reference: The impact of narcolepsy on social relationships in young adults. J Clin Sleep Med. 2022 12 01; 18(12):2751-2761.
journal title abbreviation: J Clin Sleep Med
publication date: 2022-12-01T00:00:00
year: 2022
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 452802
type: Authorship
author rank in publication: 1
linked author: Scammell, Thomas
linked information resource: Focal deletion of the adenosine A1 receptor in adult mice using an adeno-associated viral vector.

Authorship 1506044
type: Authorship
author rank in publication: 4
linked author: Scammell, Thomas
linked information resource: Clinical considerations for the diagnosis of idiopathic hypersomnia.

Clinical considerations for the diagnosis of idiopathic hypersomnia.
PubMed Identifier: 36401976
author list: Dauvilliers Y, Bogan RK, Arnulf I, Scammell TE, St Louis EK, Thorpy MJ
published in: Sleep medicine reviews
information resource reference: Clinical considerations for the diagnosis of idiopathic hypersomnia. Sleep Med Rev. 2022 12; 66:101709.
journal title abbreviation: Sleep Med Rev
publication date: 2022-10-31T00:00:00
year: 2022
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 200801
type: Authorship
author rank in publication: 6
linked author: Scammell, Thomas
linked information resource: Orexin-immunoreactive inputs to rat sympathetic preganglionic neurons.

Authorship 187466
type: Authorship
author rank in publication: 1
linked author: Scammell, Thomas
linked information resource: Is low histamine a fundamental cause of sleepiness in narcolepsy and idiopathic hypersomnia?

Authorship 1560044
type: Authorship
author rank in publication: 11
linked author: Scammell, Thomas
linked information resource: Oral Orexin Receptor 2 Agonist in Narcolepsy Type 1.

Authorship 1558196
type: Authorship
author rank in publication: 2
linked author: Scammell, Thomas
linked information resource: Number, Duration, and Distribution of Wake Bouts in Patients with Insomnia Disorder: Effect of Daridorexant and Zolpidem.

Number, Duration, and Distribution of Wake Bouts in Patients with Insomnia Disorder: Effect of Daridorexant and Zolpidem.
PubMed Identifier: 37477771
author list: Di Marco T, Scammell TE, Meinel M, Seboek Kinter D, Datta AN, Zammit G, Dauvilliers Y
published in: CNS drugs
information resource reference: Number, Duration, and Distribution of Wake Bouts in Patients with Insomnia Disorder: Effect of Daridorexant and Zolpidem. CNS Drugs. 2023 07; 37(7):639-653.
journal title abbreviation: CNS Drugs
publication date: 2023-07-21T00:00:00
year: 2023
type: Academic Article
type: Article
type: Document
type: Information Resource

Oral Orexin Receptor 2 Agonist in Narcolepsy Type 1.
PubMed Identifier: 37494485
author list: Dauvilliers Y, Mignot E, Del Río Villegas R, Du Y, Hanson E, Inoue Y, Kadali H, Koundourakis E, Meyer S, Rogers R, Scammell TE, Sheikh SI, Swick T, Szakács Z, von Rosenstiel P, Wu J, Zeitz H, Murthy NV, Plazzi G, von Hehn C
published in: The New England journal of medicine
information resource reference: Oral Orexin Receptor 2 Agonist in Narcolepsy Type 1. N Engl J Med. 2023 07 27; 389(4):309-321.
journal title abbreviation: N Engl J Med
publication date: 2023-07-27T00:00:00
year: 2023
type: Academic Article
type: Article
type: Document
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Authorship 314968
type: Authorship
author rank in publication: 4
linked author: Scammell, Thomas
linked information resource: Running promotes wakefulness and increases cataplexy in orexin knockout mice.

Authorship 1582516
type: Authorship
author rank in publication: 2
linked author: Scammell, Thomas
linked information resource: Harriet Tubman's Hypersomnia: Insights from Historical and Medical Perspectives.

Harriet Tubman's Hypersomnia: Insights from Historical and Medical Perspectives.
PubMed Identifier: 37740167
author list: Balmuth EA, Scammell TE
published in: Journal of general internal medicine
information resource reference: Harriet Tubman's Hypersomnia: Insights from Historical and Medical Perspectives. J Gen Intern Med. 2023 12; 38(16):3621-3627.
journal title abbreviation: J Gen Intern Med
publication date: 2023-09-22T00:00:00
year: 2023
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1595084
type: Authorship
author rank in publication: 2
linked author: Scammell, Thomas
linked information resource: What is cataplexy?

What is cataplexy?
PubMed Identifier: 37788645
author list: Blattner MS, Scammell TE
published in: Sleep
information resource reference: What is cataplexy? Sleep. 2024 Nov 08; 47(11).
journal title abbreviation: Sleep
publication date: 2024-11-08T00:00:00
year: 2024
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 498124
type: Authorship
author rank in publication: 10
linked author: Scammell, Thomas
linked information resource: Orexin receptor 2 expression in the posterior hypothalamus rescues sleepiness in narcoleptic mice.

Authorship 560437
type: Authorship
author rank in publication: 1
linked author: Scammell, Thomas
linked information resource: Coexistence of narcolepsy and Alzheimer's disease.

Afferent projections to the Calca /CGRP-expressing parabrachial neurons in mice.
PubMed Identifier: 38766214
author list: Korkutata M, De Luca R, Fitzgerald B, Arrigoni E, Scammell TE
published in: bioRxiv : the preprint server for biology
information resource reference: Afferent projections to the Calca /CGRP-expressing parabrachial neurons in mice. bioRxiv. 2024 May 08.
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publication date: 2024-05-08T00:00:00
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type: Document
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Authorship 1647793
type: Authorship
author rank in publication: 5
linked author: Scammell, Thomas
linked information resource: Afferent projections to the Calca /CGRP-expressing parabrachial neurons in mice.

Authorship 1648342
type: Authorship
author rank in publication: 14
linked author: Scammell, Thomas
linked information resource: Nociceptor spontaneous activity is responsible for fragmenting non-rapid eye movement sleep in mouse models of neuropathic pain.

Authorship 1647105
type: Authorship
author rank in publication: 15
linked author: Scammell, Thomas
linked information resource: Effect of daridorexant on sleep architecture in patients with chronic insomnia disorder: a pooled post hoc analysis of two randomized phase 3 clinical studies.

Effect of daridorexant on sleep architecture in patients with chronic insomnia disorder: a pooled post hoc analysis of two randomized phase 3 clinical studies.
PubMed Identifier: 38644625
author list: Di Marco T, Djonlagic I, Dauvilliers Y, Sadeghi K, Little D, Datta AN, Hubbard J, Hajak G, Krystal A, Olivieri A, Parrino L, Puryear CB, Zammit G, Donoghue J, Scammell TE
published in: Sleep
information resource reference: Effect of daridorexant on sleep architecture in patients with chronic insomnia disorder: a pooled post hoc analysis of two randomized phase 3 clinical studies. Sleep. 2024 11 08; 47(11).
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publication date: 2024-11-08T00:00:00
year: 2024
type: Academic Article
type: Article
type: Document
type: Information Resource

Nociceptor spontaneous activity is responsible for fragmenting non-rapid eye movement sleep in mouse models of neuropathic pain.
PubMed Identifier: 38630850
author list: Alexandre C, Miracca G, Holanda VD, Sharma A, Kourbanova K, Ferreira A, Bicca MA, Zeng X, Nassar VA, Lee S, Kaur S, Sarma SV, Sacré P, Scammell TE, Woolf CJ, Latremoliere A
published in: Science translational medicine
information resource reference: Nociceptor spontaneous activity is responsible for fragmenting non-rapid eye movement sleep in mouse models of neuropathic pain. Sci Transl Med. 2024 04 17; 16(743):eadg3036.
journal title abbreviation: Sci Transl Med
publication date: 2024-04-17T00:00:00
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type: Article
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Authorship 314673
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author rank in publication: 5
linked author: Scammell, Thomas
linked information resource: Diurnal variation in CSF orexin-A in healthy male subjects.

Authorship 332551
type: Authorship
author rank in publication: 7
linked author: Scammell, Thomas
linked information resource: Thalamic Cav3.1 T-type Ca2+ channel plays a crucial role in stabilizing sleep.

Authorship 1659148
type: Authorship
author rank in publication: 2
linked author: Scammell, Thomas
linked information resource: Hyperarousal features in the sleep architecture of individuals with and without insomnia.

Hyperarousal features in the sleep architecture of individuals with and without insomnia.
PubMed Identifier: 38853521
author list: Di Marco T, Scammell TE, Sadeghi K, Datta AN, Little D, Tjiptarto N, Djonlagic I, Olivieri A, Zammit G, Krystal A, Pathmanathan J, Donoghue J, Hubbard J, Dauvilliers Y
published in: Journal of sleep research
information resource reference: Hyperarousal features in the sleep architecture of individuals with and without insomnia. J Sleep Res. 2025 02; 34(1):e14256.
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publication date: 2024-06-09T00:00:00
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type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1663441
type: Authorship
author rank in publication: 3
linked author: Scammell, Thomas
linked information resource: Impaired cognition in narcolepsy: clinical and neurobiological perspectives.

Impaired cognition in narcolepsy: clinical and neurobiological perspectives.
PubMed Identifier: 38943485
author list: Cano CA, Harel BT, Scammell TE
published in: Sleep
information resource reference: Impaired cognition in narcolepsy: clinical and neurobiological perspectives. Sleep. 2024 09 09; 47(9).
journal title abbreviation: Sleep
publication date: 2024-09-09T00:00:00
year: 2024
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1668285
type: Authorship
author rank in publication: 5
linked author: Scammell, Thomas
linked information resource: The nature and magnitude of cognitive impairment in narcolepsy type 1, narcolepsy type 2, and idiopathic hypersomnia: a meta-analysis.

The nature and magnitude of cognitive impairment in narcolepsy type 1, narcolepsy type 2, and idiopathic hypersomnia: a meta-analysis.
PubMed Identifier: 39036743
author list: Harel BT, Gattuso JJ, Latzman RD, Maruff P, Scammell TE, Plazzi G
published in: Sleep advances : a journal of the Sleep Research Society
information resource reference: The nature and magnitude of cognitive impairment in narcolepsy type 1, narcolepsy type 2, and idiopathic hypersomnia: a meta-analysis. Sleep Adv. 2024; 5(1):zpae043.
journal title abbreviation: Sleep Adv
publication date: 2024-06-26T00:00:00
year: 2024
type: Academic Article
type: Article
type: Document
type: Information Resource

Instructor in Neurology
is primary position: true
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position in division: Sleep Medicine
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HR job title: Instructor in Neurology
position in organization: Brigham and Women's Hospital

Authorship 1679080
type: Authorship
author rank in publication: 5
linked author: Scammell, Thomas
linked information resource: Cardiovascular Risks in People With Narcolepsy: Expert Panel Consensus Recommendations.

Cardiovascular Risks in People With Narcolepsy: Expert Panel Consensus Recommendations.
PubMed Identifier: 39119988
author list: Kwon Y, Gami AS, Javaheri S, Pressman GS, Scammell TE, Surkin LA, Zee PC
published in: Journal of the American Heart Association
information resource reference: Cardiovascular Risks in People With Narcolepsy: Expert Panel Consensus Recommendations. J Am Heart Assoc. 2024 Aug 20; 13(16):e035168.
journal title abbreviation: J Am Heart Assoc
publication date: 2024-08-09T00:00:00
year: 2024
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 668386
type: Authorship
author rank in publication: 5
linked author: Scammell, Thomas
linked information resource: Amygdala lesions reduce cataplexy in orexin knock-out mice.

Authorship 646166
type: Authorship
author rank in publication: 8
linked author: Scammell, Thomas
linked information resource: Role of the medial prefrontal cortex in cataplexy.

Authorship 645678
type: Authorship
author rank in publication: 8
linked author: Scammell, Thomas
linked information resource: Orexin gene therapy restores the timing and maintenance of wakefulness in narcoleptic mice.

Role of the medial prefrontal cortex in cataplexy.
PubMed Identifier: 23739971
author list: Oishi Y, Williams RH, Agostinelli L, Arrigoni E, Fuller PM, Mochizuki T, Saper CB, Scammell TE
published in: The Journal of neuroscience : the official journal of the Society for Neuroscience
information resource reference: Role of the medial prefrontal cortex in cataplexy. J Neurosci. 2013 Jun 05; 33(23):9743-51.
journal title abbreviation: J Neurosci
publication date: 2013-06-05T00:00:00
year: 2013
type: Academic Article
type: Article
type: Document
type: Information Resource

Amygdala lesions reduce cataplexy in orexin knock-out mice.
PubMed Identifier: 23739970
author list: Burgess CR, Oishi Y, Mochizuki T, Peever JH, Scammell TE
published in: The Journal of neuroscience : the official journal of the Society for Neuroscience
information resource reference: Amygdala lesions reduce cataplexy in orexin knock-out mice. J Neurosci. 2013 Jun 05; 33(23):9734-42.
journal title abbreviation: J Neurosci
publication date: 2013-06-05T00:00:00
year: 2013
type: Academic Article
type: Article
type: Document
type: Information Resource

Orexin gene therapy restores the timing and maintenance of wakefulness in narcoleptic mice.
PubMed Identifier: 23904672
author list: Kantor S, Mochizuki T, Lops SN, Ko B, Clain E, Clark E, Yamamoto M, Scammell TE
published in: Sleep
information resource reference: Orexin gene therapy restores the timing and maintenance of wakefulness in narcoleptic mice. Sleep. 2013 Aug 01; 36(8):1129-38.
journal title abbreviation: Sleep
publication date: 2013-08-01T00:00:00
year: 2013
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1694473
type: Authorship
author rank in publication: 9
linked author: Scammell, Thomas
linked information resource: Impaired sleep-dependent memory consolidation in pediatric narcolepsy type 1.

Authorship 1701805
type: Authorship
author rank in publication: 7
linked author: Scammell, Thomas
linked information resource: Characterizing disrupted nighttime sleep and associated functional outcomes in youth with narcolepsy type 1.

Impaired sleep-dependent memory consolidation in pediatric narcolepsy type 1.
PubMed Identifier: 39420719
author list: Maski K, Heckler G, Worhach J, Mylonas D, Wang G, Szilagyi K, Zhang B, Diniz Behn C, Scammell TE, Stickgold R
published in: Sleep
information resource reference: Impaired sleep-dependent memory consolidation in pediatric narcolepsy type 1. Sleep. 2025 Feb 10; 48(2).
journal title abbreviation: Sleep
publication date: 2025-02-10T00:00:00
year: 2025
type: Academic Article
type: Article
type: Document
type: Information Resource

Characterizing disrupted nighttime sleep and associated functional outcomes in youth with narcolepsy type 1.
PubMed Identifier: 39415540
author list: Heckler G, Worhach J, Wang G, Szilagyi K, Zhang B, Behn CD, Scammell T, Maski K
published in: Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine
information resource reference: Characterizing disrupted nighttime sleep and associated functional outcomes in youth with narcolepsy type 1. J Clin Sleep Med. 2025 Feb 01; 21(2):355-363.
journal title abbreviation: J Clin Sleep Med
publication date: 2025-02-01T00:00:00
year: 2025
type: Academic Article
type: Article
type: Document
type: Information Resource

The impact of idiopathic hypersomnia on the social lives of young adults.
PubMed Identifier: 39743439
author list: Davidson RD, Blattner M, Scammell TE, Zhou ES
published in: Sleep health
information resource reference: The impact of idiopathic hypersomnia on the social lives of young adults. Sleep Health. 2025 Feb; 11(1):113-119.
journal title abbreviation: Sleep Health
publication date: 2024-12-31T00:00:00
year: 2024
type: Academic Article
type: Article
type: Document
type: Information Resource

Afferent Projections to the Calca/CGRP-Expressing Parabrachial Neurons in Mice.
PubMed Identifier: 39801453
author list: Korkutata M, De Luca R, Fitzgerald B, Khanday MA, Arrigoni E, Scammell TE
published in: The Journal of comparative neurology
information resource reference: Afferent Projections to the Calca/CGRP-Expressing Parabrachial Neurons in Mice. J Comp Neurol. 2025 Jan; 533(1):e70018.
journal title abbreviation: J Comp Neurol
publication date: 2025-01-01T00:00:00
year: 2025
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1718350
type: Authorship
author rank in publication: 6
linked author: Scammell, Thomas
linked information resource: Afferent Projections to the Calca/CGRP-Expressing Parabrachial Neurons in Mice.

Authorship 1716990
type: Authorship
author rank in publication: 3
linked author: Scammell, Thomas
linked information resource: The impact of idiopathic hypersomnia on the social lives of young adults.

Authorship 239465
type: Authorship
author rank in publication: 1
linked author: Scammell, Thomas
linked information resource: Orexin, drugs and motivated behaviors.

Authorship 673955
type: Authorship
author rank in publication: 3
linked author: Scammell, Thomas
linked information resource: Control of arousal by the orexin neurons.

Control of arousal by the orexin neurons.
PubMed Identifier: 23683477
author list: Alexandre C, Andermann ML, Scammell TE
published in: Current opinion in neurobiology
information resource reference: Control of arousal by the orexin neurons. Curr Opin Neurobiol. 2013 Oct; 23(5):752-9.
journal title abbreviation: Curr Opin Neurobiol
publication date: 2013-05-15T00:00:00
year: 2013
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 678970
type: Authorship
author rank in publication: 2
linked author: Scammell, Thomas
linked information resource: Emerging therapeutics in sleep.

Authorship 678857
type: Authorship
author rank in publication: 1
linked author: Scammell, Thomas
linked information resource: Threat of nuclear war.

Threat of nuclear war.
PubMed Identifier: 3794610
author list: Scammell T
published in: The Journal of family practice
information resource reference: Threat of nuclear war. J Fam Pract. 1987 Jan; 24(1):18-20.
journal title abbreviation: J Fam Pract
publication date: 1987-01-01T00:00:00
year: 1987
type: Academic Article
type: Article
type: Document
type: Information Resource

Emerging therapeutics in sleep.
PubMed Identifier: 24038193
author list: Saper CB, Scammell TE
published in: Annals of neurology
information resource reference: Emerging therapeutics in sleep. Ann Neurol. 2013 Sep; 74(3):435-40.
journal title abbreviation: Ann Neurol
publication date: 2013-09-01T00:00:00
year: 2013
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 313456
type: Authorship
author rank in publication: 1
linked author: Scammell, Thomas
linked information resource: Inhibition of nitric oxide synthase produces hypothermia and depresses lipopolysaccharide fever.

Associate Professor of Neurology
is primary position: true
position in department: Neurology
position in division: https://connects.catalyst.harvard.edu/Profiles/profile/1229413
sort order: 1
type: Position
HR job title: Associate Professor of Neurology
position in organization: Beth Israel Deaconess Medical Center

Authorship 1749756
type: Authorship
author rank in publication: 6
linked author: Scammell, Thomas
linked information resource: An orexin agonist promotes wakefulness and inhibits cataplexy through distinct brain regions.

An orexin agonist promotes wakefulness and inhibits cataplexy through distinct brain regions.
PubMed Identifier: 40233754
author list: Ishikawa T, Kurimoto E, Joyal AA, Koike T, Kimura H, Scammell TE
published in: Current biology : CB
information resource reference: An orexin agonist promotes wakefulness and inhibits cataplexy through distinct brain regions. Curr Biol. 2025 May 05; 35(9):2088-2099.e4.
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publication date: 2025-04-14T00:00:00
year: 2025
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 174099
type: Authorship
author rank in publication: 1
linked author: Scammell, Thomas
linked information resource: Orexin receptors: pharmacology and therapeutic opportunities.

Authorship 38403
type: Authorship
author rank in publication: 3
linked author: Scammell, Thomas
linked information resource: Neural circuitry engaged by prostaglandins during the sickness syndrome.

Authorship 703645
type: Authorship
author rank in publication: 8
linked author: Scammell, Thomas
linked information resource: Increase of histaminergic tuberomammillary neurons in narcolepsy.

Increase of histaminergic tuberomammillary neurons in narcolepsy.
PubMed Identifier: 24006291
author list: Valko PO, Gavrilov YV, Yamamoto M, Reddy H, Haybaeck J, Mignot E, Baumann CR, Scammell TE
published in: Annals of neurology
information resource reference: Increase of histaminergic tuberomammillary neurons in narcolepsy. Ann Neurol. 2013 Dec; 74(6):794-804.
journal title abbreviation: Ann Neurol
publication date: 2013-12-01T00:00:00
year: 2013
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 24559
type: Authorship
author rank in publication: 1
linked author: Scammell, Thomas
linked information resource: Activation of ventrolateral preoptic neurons by the somnogen prostaglandin D2.

Authorship 178508
type: Authorship
author rank in publication: 3
linked author: Scammell, Thomas
linked information resource: Severe acute disseminated encephalomyelitis with normal MRI at presentation.

Authorship 723165
type: Authorship
author rank in publication: 3
linked author: Scammell, Thomas
linked information resource: Delusional confusion of dreaming and reality in narcolepsy.

Authorship 720520
type: Authorship
author rank in publication: 5
linked author: Scammell, Thomas
linked information resource: Carbachol excites sublaterodorsal nucleus neurons projecting to the spinal cord.

Delusional confusion of dreaming and reality in narcolepsy.
PubMed Identifier: 24501437
author list: Wamsley E, Donjacour CE, Scammell TE, Lammers GJ, Stickgold R
published in: Sleep
information resource reference: Delusional confusion of dreaming and reality in narcolepsy. Sleep. 2014 Feb 01; 37(2):419-22.
journal title abbreviation: Sleep
publication date: 2014-02-01T00:00:00
year: 2014
type: Academic Article
type: Article
type: Document
type: Information Resource

Carbachol excites sublaterodorsal nucleus neurons projecting to the spinal cord.
PubMed Identifier: 24344163
author list: Weng FJ, Williams RH, Hawryluk JM, Lu J, Scammell TE, Saper CB, Arrigoni E
published in: The Journal of physiology
information resource reference: Carbachol excites sublaterodorsal nucleus neurons projecting to the spinal cord. J Physiol. 2014 Apr 01; 592(7):1601-17.
journal title abbreviation: J Physiol
publication date: 2013-12-16T00:00:00
year: 2013
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 2320
type: Authorship
author rank in publication: 2
linked author: Scammell, Thomas
linked information resource: Parkinson's disease, sleepiness and hypocretin/orexin.

Frank Baldino, Jr., Ph.D. Professor of Sleep Medicine
is primary position: true
position in department: Medicine
position in division: Sleep Medicine
sort order: 1
type: Position
HR job title: Frank Baldino, Jr., Ph.D. Professor of Sleep Medicine
position in organization: Brigham and Women's Hospital

Authorship 727054
type: Authorship
author rank in publication: 6
linked author: Scammell, Thomas
linked information resource: Optogenetic-mediated release of histamine reveals distal and autoregulatory mechanisms for controlling arousal.

Optogenetic-mediated release of histamine reveals distal and autoregulatory mechanisms for controlling arousal.
PubMed Identifier: 24760861
author list: Williams RH, Chee MJ, Kroeger D, Ferrari LL, Maratos-Flier E, Scammell TE, Arrigoni E
published in: The Journal of neuroscience : the official journal of the Society for Neuroscience
information resource reference: Optogenetic-mediated release of histamine reveals distal and autoregulatory mechanisms for controlling arousal. J Neurosci. 2014 Apr 23; 34(17):6023-9.
journal title abbreviation: J Neurosci
publication date: 2014-04-23T00:00:00
year: 2014
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 732105
type: Authorship
author rank in publication: 11
linked author: Scammell, Thomas
linked information resource: Challenges in diagnosing narcolepsy without cataplexy: a consensus statement.

Challenges in diagnosing narcolepsy without cataplexy: a consensus statement.
PubMed Identifier: 24882898
author list: Baumann CR, Mignot E, Lammers GJ, Overeem S, Arnulf I, Rye D, Dauvilliers Y, Honda M, Owens JA, Plazzi G, Scammell TE
published in: Sleep
information resource reference: Challenges in diagnosing narcolepsy without cataplexy: a consensus statement. Sleep. 2014 Jun 01; 37(6):1035-42.
journal title abbreviation: Sleep
publication date: 2014-06-01T00:00:00
year: 2014
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1829775
type: Authorship
author rank in publication: 8
linked author: Scammell, Thomas
linked information resource: Effects of Oveporexton, an Orexin Receptor 2-Selective Agonist, on Cognition in Narcolepsy Type 1: A Secondary Analysis of a Randomized Clinical Trial.

Effects of Oveporexton, an Orexin Receptor 2-Selective Agonist, on Cognition in Narcolepsy Type 1: A Secondary Analysis of a Randomized Clinical Trial.
PubMed Identifier: 41359331
author list: Lammers GJ, Plazzi G, Mignot E, Pizza F, Dauvilliers Y, Barateau L, Maruff P, Scammell TE, Latzman RD, Naylor M, Olsson T, Stukalin E, Tanaka S, Volfson D, Khachadourian V, Harel BT
published in: JAMA neurology
information resource reference: Effects of Oveporexton, an Orexin Receptor 2-Selective Agonist, on Cognition in Narcolepsy Type 1: A Secondary Analysis of a Randomized Clinical Trial. JAMA Neurol. 2026 Feb 01; 83(2):145-152.
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publication date: 2026-02-01T00:00:00
year: 2026
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 414108
type: Authorship
author rank in publication: 4
linked author: Scammell, Thomas
linked information resource: Wake-related activity of tuberomammillary neurons in rats.

Peter C. Farrell Professor of Sleep Medicine
is primary position: true
position in department: Medicine
position in division: Sleep Medicine
sort order: 1
type: Position
HR job title: Peter C. Farrell Professor of Sleep Medicine
position in organization: Brigham and Women's Hospital

Associate Professor of Neurology
is primary position: true
position in department: Neurology
position in division: https://connects.catalyst.harvard.edu/Profiles/profile/1229413
sort order: 1
type: Position
HR job title: Associate Professor of Neurology
position in organization: Boston Children's Hospital

Authorship 506528
type: Authorship
author rank in publication: 2
linked author: Scammell, Thomas
linked information resource: Pharmacotherapy for cataplexy.

Authorship 755140
type: Authorship
author rank in publication: 7
linked author: Scammell, Thomas
linked information resource: SCOPRISM: a new algorithm for automatic sleep scoring in mice.

SCOPRISM: a new algorithm for automatic sleep scoring in mice.
PubMed Identifier: 25092499
author list: Bastianini S, Berteotti C, Gabrielli A, Del Vecchio F, Amici R, Alexandre C, Scammell TE, Gazea M, Kimura M, Lo Martire V, Silvani A, Zoccoli G
published in: Journal of neuroscience methods
information resource reference: SCOPRISM: a new algorithm for automatic sleep scoring in mice. J Neurosci Methods. 2014 Sep 30; 235:277-84.
journal title abbreviation: J Neurosci Methods
publication date: 2014-08-01T00:00:00
year: 2014
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 6872
type: Authorship
author rank in publication: 4
linked author: Scammell, Thomas
linked information resource: Common scale-invariant patterns of sleep-wake transitions across mammalian species.

Authorship 525098
type: Authorship
author rank in publication: 2
linked author: Scammell, Thomas
linked information resource: Modafinil: a drug in search of a mechanism.

Authorship 87231
type: Authorship
author rank in publication: 1
linked author: Scammell, Thomas
linked information resource: The frustrating and mostly fruitless search for an autoimmune cause of narcolepsy.

Authorship 417772
type: Authorship
author rank in publication: 3
linked author: Scammell, Thomas
linked information resource: Activation of the basal forebrain by the orexin/hypocretin neurones.

Authorship 485931
type: Authorship
author rank in publication: 4
linked author: Scammell, Thomas
linked information resource: Melanopsin in cells of origin of the retinohypothalamic tract.

Authorship 46390
type: Authorship
author rank in publication: 3
linked author: Scammell, Thomas
linked information resource: Polymorphisms in hypocretin/orexin pathway genes and narcolepsy.

Authorship 500720
type: Authorship
author rank in publication: 5
linked author: Scammell, Thomas
linked information resource: Afferents to the orexin neurons of the rat brain.

Authorship 501156
type: Authorship
author rank in publication: 4
linked author: Scammell, Thomas
linked information resource: Feeding-elicited cataplexy in orexin knockout mice.

Authorship 524480
type: Authorship
author rank in publication: 5
linked author: Scammell, Thomas
linked information resource: Narcolepsy caused by acute disseminated encephalomyelitis.

Authorship 533716
type: Authorship
author rank in publication: 1
linked author: Scammell, Thomas
linked information resource: Microinjection of a cyclooxygenase inhibitor into the anteroventral preoptic region attenuates LPS fever.

Authorship 30775
type: Authorship
author rank in publication: 2
linked author: Scammell, Thomas
linked information resource: Sleep neurobiology from a clinical perspective.

Authorship 226111
type: Authorship
author rank in publication: 5
linked author: Scammell, Thomas
linked information resource: Regulation of daily locomotor activity and sleep by hypothalamic EGF receptor signalling.

Authorship 509723
type: Authorship
author rank in publication: 5
linked author: Scammell, Thomas
linked information resource: Modafinil more effectively induces wakefulness in orexin-null mice than in wild-type littermates.

Authorship 411790
type: Authorship
author rank in publication: 4
linked author: Scammell, Thomas
linked information resource: Effects of adenosine on gabaergic synaptic inputs to identified ventrolateral preoptic neurons.

Authorship 425117
type: Authorship
author rank in publication: 1
linked author: Scammell, Thomas
linked information resource: No evidence for a circadian rhythm of protein synthesis in the rat suprachiasmatic nuclei.

Authorship 320176
type: Authorship
author rank in publication: 5
linked author: Scammell, Thomas
linked information resource: Inter-hemispheric oscillations in human sleep.

Authorship 444808
type: Authorship
author rank in publication: 2
linked author: Scammell, Thomas
linked information resource: Critical role of dorsomedial hypothalamic nucleus in a wide range of behavioral circadian rhythms.

Authorship 571424
type: Authorship
author rank in publication: 5
linked author: Scammell, Thomas
linked information resource: Afferents to the ventrolateral preoptic nucleus.

Authorship 260505
type: Authorship
author rank in publication: 9
linked author: Scammell, Thomas
linked information resource: Concomitant loss of dynorphin, NARP, and orexin in narcolepsy.

Authorship 198
type: Authorship
author rank in publication: 2
linked author: Scammell, Thomas
linked information resource: Orexin/Hypocretin: wired for wakefulness.

Authorship 64151
type: Authorship
author rank in publication: 5
linked author: Scammell, Thomas
linked information resource: Regulation of daily locomotor activity and sleep by hypothalamic EGF receptor signaling.

Authorship 89582
type: Authorship
author rank in publication: 1
linked author: Scammell, Thomas
linked information resource: Ventromedial preoptic prostaglandin E2 activates fever-producing autonomic pathways.

Authorship 204861
type: Authorship
author rank in publication: 4
linked author: Scammell, Thomas
linked information resource: Cerebral deep venous thrombosis presenting as acute micrographia and hypophonia.

Authorship 480877
type: Authorship
author rank in publication: 3
linked author: Scammell, Thomas
linked information resource: Mathematical model of network dynamics governing mouse sleep-wake behavior.

Authorship 197777
type: Authorship
author rank in publication: 1
linked author: Scammell, Thomas
linked information resource: Orexins: looking forward to sleep, back at addiction.

Authorship 529107
type: Authorship
author rank in publication: 5
linked author: Scammell, Thomas
linked information resource: Sleep state switching.

Authorship 277882
type: Authorship
author rank in publication: 1
linked author: Scammell, Thomas
linked information resource: The neurobiology, diagnosis, and treatment of narcolepsy.

Authorship 137801
type: Authorship
author rank in publication: 16
linked author: Scammell, Thomas
linked information resource: Narcolepsy as an adverse event following immunization: case definition and guidelines for data collection, analysis and presentation.

Authorship 275489
type: Authorship
author rank in publication: 3
linked author: Scammell, Thomas
linked information resource: Effects of vagus nerve stimulation on respiration during sleep.

Authorship 330381
type: Authorship
author rank in publication: 1
linked author: Scammell, Thomas
linked information resource: Modafinil: a novel stimulant for the treatment of narcolepsy.

Authorship 423456
type: Authorship
author rank in publication: 4
linked author: Scammell, Thomas
linked information resource: Silent functional magnetic resonance imaging demonstrates focal activation in rapid eye movement sleep.

Authorship 431382
type: Authorship
author rank in publication: 8
linked author: Scammell, Thomas
linked information resource: Fos expression in orexin neurons varies with behavioral state.

Authorship 4577
type: Authorship
author rank in publication: 5
linked author: Scammell, Thomas
linked information resource: Narcolepsy in orexin knockout mice: molecular genetics of sleep regulation.

Authorship 509336
type: Authorship
author rank in publication: 2
linked author: Scammell, Thomas
linked information resource: Hypocretin/orexin and sleep: implications for the pathophysiology and diagnosis of narcolepsy.

Authorship 542241
type: Authorship
author rank in publication: 6
linked author: Scammell, Thomas
linked information resource: Behavioral state instability in orexin knock-out mice.

Authorship 800211
type: Authorship
author rank in publication: 3
linked author: Scammell, Thomas
linked information resource: Usefulness of a Nocturnal SOREMP for Diagnosing Narcolepsy with Cataplexy in a Pediatric Population.

Authorship 806083
type: Authorship
author rank in publication: 8
linked author: Scammell, Thomas
linked information resource: Damage to histaminergic tuberomammillary neurons and other hypothalamic neurons with traumatic brain injury.

Authorship 791725
type: Authorship
author rank in publication: 1
linked author: Scammell, Thomas
linked information resource: Overview of sleep: the neurologic processes of the sleep-wake cycle.

Damage to histaminergic tuberomammillary neurons and other hypothalamic neurons with traumatic brain injury.
PubMed Identifier: 25363332
author list: Valko PO, Gavrilov YV, Yamamoto M, Finn K, Reddy H, Haybaeck J, Weis S, Scammell TE, Baumann CR
published in: Annals of neurology
information resource reference: Damage to histaminergic tuberomammillary neurons and other hypothalamic neurons with traumatic brain injury. Ann Neurol. 2015 Jan; 77(1):177-82.
journal title abbreviation: Ann Neurol
publication date: 2014-11-20T00:00:00
year: 2014
type: Academic Article
type: Article
type: Document
type: Information Resource

Overview of sleep: the neurologic processes of the sleep-wake cycle.
PubMed Identifier: 26035194
author list: Scammell TE
published in: The Journal of clinical psychiatry
information resource reference: Overview of sleep: the neurologic processes of the sleep-wake cycle. J Clin Psychiatry. 2015 May; 76(5):e13.
journal title abbreviation: J Clin Psychiatry
publication date: 2015-05-01T00:00:00
year: 2015
type: Academic Article
type: Article
type: Document
type: Information Resource

Usefulness of a Nocturnal SOREMP for Diagnosing Narcolepsy with Cataplexy in a Pediatric Population.
PubMed Identifier: 25325489
author list: Reiter J, Katz E, Scammell TE, Maski K
published in: Sleep
information resource reference: Usefulness of a Nocturnal SOREMP for Diagnosing Narcolepsy with Cataplexy in a Pediatric Population. Sleep. 2015 Jun 01; 38(6):859-65.
journal title abbreviation: Sleep
publication date: 2015-06-01T00:00:00
year: 2015
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 31244
type: Authorship
author rank in publication: 2
linked author: Scammell, Thomas
linked information resource: Mechanisms of CNS response to systemic immune challenge: the febrile response.

Authorship 315914
type: Authorship
author rank in publication: 6
linked author: Scammell, Thomas
linked information resource: Hcrtr1 and 2 signaling differentially regulates depression-like behaviors.

Authorship 376175
type: Authorship
author rank in publication: 1
linked author: Scammell, Thomas
linked information resource: An adenosine A2a agonist increases sleep and induces Fos in ventrolateral preoptic neurons.

Authorship 461059
type: Authorship
author rank in publication: 5
linked author: Scammell, Thomas
linked information resource: Delayed orexin signaling consolidates wakefulness and sleep: physiology and modeling.

Authorship 468934
type: Authorship
author rank in publication: 5
linked author: Scammell, Thomas
linked information resource: Deletion of presynaptic adenosine A1 receptors impairs the recovery of synaptic transmission after hypoxia.

Authorship 812286
type: Authorship
author rank in publication: 3
linked author: Scammell, Thomas
linked information resource: The roles of prostaglandin E2 and D2 in lipopolysaccharide-mediated changes in sleep.

The roles of prostaglandin E2 and D2 in lipopolysaccharide-mediated changes in sleep.
PubMed Identifier: 25532785
author list: Oishi Y, Yoshida K, Scammell TE, Urade Y, Lazarus M, Saper CB
published in: Brain, behavior, and immunity
information resource reference: The roles of prostaglandin E2 and D2 in lipopolysaccharide-mediated changes in sleep. Brain Behav Immun. 2015 Jul; 47:172-7.
journal title abbreviation: Brain Behav Immun
publication date: 2014-12-20T00:00:00
year: 2014
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 312993
type: Authorship
author rank in publication: 4
linked author: Scammell, Thomas
linked information resource: Reward-seeking behavior in human narcolepsy.

Authorship 483127
type: Authorship
author rank in publication: 5
linked author: Scammell, Thomas
linked information resource: Do enteric neurons make hypocretin?

Authorship 510106
type: Authorship
author rank in publication: 2
linked author: Scammell, Thomas
linked information resource: The trouble with Tribbles: do antibodies against TRIB2 cause narcolepsy?

Authorship 573152
type: Authorship
author rank in publication: 9
linked author: Scammell, Thomas
linked information resource: Loss of hypocretin (orexin) neurons with traumatic brain injury.

Authorship 841586
type: Authorship
author rank in publication: 8
linked author: Scammell, Thomas
linked information resource: Suppression of Locomotor Activity in Female C57Bl/6J Mice Treated with Interleukin-1ß: Investigating a Method for the Study of Fatigue in Laboratory Animals.

Suppression of Locomotor Activity in Female C57Bl/6J Mice Treated with Interleukin-1ß: Investigating a Method for the Study of Fatigue in Laboratory Animals.
PubMed Identifier: 26469939
author list: Bonsall DR, Kim H, Tocci C, Ndiaye A, Petronzio A, McKay-Corkum G, Molyneux PC, Scammell TE, Harrington ME
published in: PloS one
information resource reference: Suppression of Locomotor Activity in Female C57Bl/6J Mice Treated with Interleukin-1ß: Investigating a Method for the Study of Fatigue in Laboratory Animals. PLoS One. 2015; 10(10):e0140678.
journal title abbreviation: PLoS One
publication date: 2015-10-15T00:00:00
year: 2015
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 851968
type: Authorship
author rank in publication: 18
linked author: Scammell, Thomas
linked information resource: Systems Genomics Identifies a Key Role for Hypocretin/Orexin Receptor-2 in Human Heart Failure.

Systems Genomics Identifies a Key Role for Hypocretin/Orexin Receptor-2 in Human Heart Failure.
PubMed Identifier: 26653627
author list: Perez MV, Pavlovic A, Shang C, Wheeler MT, Miller CL, Liu J, Dewey FE, Pan S, Thanaporn PK, Absher D, Brandimarto J, Salisbury H, Chan K, Mukherjee R, Konadhode RP, Myers RM, Sedehi D, Scammell TE, Quertermous T, Cappola T, Ashley EA
published in: Journal of the American College of Cardiology
information resource reference: Systems Genomics Identifies a Key Role for Hypocretin/Orexin Receptor-2 in Human Heart Failure. J Am Coll Cardiol. 2015 Dec 08; 66(22):2522-33.
journal title abbreviation: J Am Coll Cardiol
publication date: 2015-12-08T00:00:00
year: 2015
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 855387
type: Authorship
author rank in publication: 1
linked author: Scammell, Thomas
linked information resource: Narcolepsy.

Narcolepsy.
PubMed Identifier: 26716917
author list: Scammell TE
published in: The New England journal of medicine
information resource reference: Narcolepsy. N Engl J Med. 2015 Dec 31; 373(27):2654-62.
journal title abbreviation: N Engl J Med
publication date: 2015-12-31T00:00:00
year: 2015
type: Academic Article
type: Article
type: Document
type: Information Resource

Genetic identity of thermosensory relay neurons in the lateral parabrachial nucleus.
PubMed Identifier: 26491097
author list: Geerling JC, Kim M, Mahoney CE, Abbott SB, Agostinelli LJ, Garfield AS, Krashes MJ, Lowell BB, Scammell TE
published in: American journal of physiology. Regulatory, integrative and comparative physiology
information resource reference: Genetic identity of thermosensory relay neurons in the lateral parabrachial nucleus. Am J Physiol Regul Integr Comp Physiol. 2016 Jan 01; 310(1):R41-54.
journal title abbreviation: Am J Physiol Regul Integr Comp Physiol
publication date: 2015-10-21T00:00:00
year: 2015
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 855834
type: Authorship
author rank in publication: 9
linked author: Scammell, Thomas
linked information resource: Genetic identity of thermosensory relay neurons in the lateral parabrachial nucleus.

Authorship 461998
type: Authorship
author rank in publication: 1
linked author: Scammell, Thomas
linked information resource: Hyperthermia induces c-fos expression in the preoptic area.

Authorship 67370
type: Authorship
author rank in publication: 4
linked author: Scammell, Thomas
linked information resource: Elevated body temperature during sleep in orexin knockout mice.

Authorship 864740
type: Authorship
author rank in publication: 5
linked author: Scammell, Thomas
linked information resource: Dynorphin inhibits basal forebrain cholinergic neurons by pre- and postsynaptic mechanisms.

Authorship 862862
type: Authorship
author rank in publication: 6
linked author: Scammell, Thomas
linked information resource: Progressive Loss of the Orexin Neurons Reveals Dual Effects on Wakefulness.

Authorship 871130
type: Authorship
author rank in publication: 6
linked author: Scammell, Thomas
linked information resource: Bradysomnia in Parkinson's disease.

Dynorphin inhibits basal forebrain cholinergic neurons by pre- and postsynaptic mechanisms.
PubMed Identifier: 26613645
author list: Ferrari LL, Agostinelli LJ, Krashes MJ, Lowell BB, Scammell TE, Arrigoni E
published in: The Journal of physiology
information resource reference: Dynorphin inhibits basal forebrain cholinergic neurons by pre- and postsynaptic mechanisms. J Physiol. 2016 Feb 15; 594(4):1069-85.
journal title abbreviation: J Physiol
publication date: 2016-01-05T00:00:00
year: 2016
type: Academic Article
type: Article
type: Document
type: Information Resource

Progressive Loss of the Orexin Neurons Reveals Dual Effects on Wakefulness.
PubMed Identifier: 26446125
author list: Branch AF, Navidi W, Tabuchi S, Terao A, Yamanaka A, Scammell TE, Diniz Behn C
published in: Sleep
information resource reference: Progressive Loss of the Orexin Neurons Reveals Dual Effects on Wakefulness. Sleep. 2016 Feb 01; 39(2):369-77.
journal title abbreviation: Sleep
publication date: 2016-02-01T00:00:00
year: 2016
type: Academic Article
type: Article
type: Document
type: Information Resource

Bradysomnia in Parkinson's disease.
PubMed Identifier: 26419612
author list: Imbach LL, Sommerauer M, Poryazova R, Werth E, Valko PO, Scammell TE, Baumann CR
published in: Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology
information resource reference: Bradysomnia in Parkinson's disease. Clin Neurophysiol. 2016 Feb; 127(2):1403-1409.
journal title abbreviation: Clin Neurophysiol
publication date: 2015-09-02T00:00:00
year: 2015
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 88980
type: Authorship
author rank in publication: 1
linked author: Scammell, Thomas
linked information resource: Wakefulness: an eye-opening perspective on orexin neurons.

Does REM Sleep Influence Cataplexy?
end date: 2010-08-31T00:00:00
start date: 2010-05-20T00:00:00
type: Mentoring - Completed Student Project
overview: Summer

Authorship 458705
type: Authorship
author rank in publication: 3
linked author: Scammell, Thomas
linked information resource: The sleep switch: hypothalamic control of sleep and wakefulness.

Circadian Rhythms in Mice with Genetic Ablation of the Orexin Neurons
end date: 2005-09-01T00:00:00
start date: 2005-07-01T00:00:00
type: Mentoring - Completed Student Project
overview: Summer

Authorship 481101
type: Authorship
author rank in publication: 1
linked author: Scammell, Thomas
linked information resource: A consensus definition of cataplexy in mouse models of narcolepsy.

Authorship 881410
type: Authorship
author rank in publication: 8
linked author: Scammell, Thomas
linked information resource: Disrupted Sleep in Narcolepsy: Exploring the Integrity of Galanin Neurons in the Ventrolateral Preoptic Area.

Disrupted Sleep in Narcolepsy: Exploring the Integrity of Galanin Neurons in the Ventrolateral Preoptic Area.
PubMed Identifier: 26951397
author list: Gavrilov YV, Ellison BA, Yamamoto M, Reddy H, Haybaeck J, Mignot E, Baumann CR, Scammell TE, Valko PO
published in: Sleep
information resource reference: Disrupted Sleep in Narcolepsy: Exploring the Integrity of Galanin Neurons in the Ventrolateral Preoptic Area. Sleep. 2016 05 01; 39(5):1059-62.
journal title abbreviation: Sleep
publication date: 2016-05-01T00:00:00
year: 2016
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 886263
type: Authorship
author rank in publication: 9
linked author: Scammell, Thomas
linked information resource: Damage to Arousal-Promoting Brainstem Neurons with Traumatic Brain Injury.

Damage to Arousal-Promoting Brainstem Neurons with Traumatic Brain Injury.
PubMed Identifier: 27091531
author list: Valko PO, Gavrilov YV, Yamamoto M, Noaín D, Reddy H, Haybaeck J, Weis S, Baumann CR, Scammell TE
published in: Sleep
information resource reference: Damage to Arousal-Promoting Brainstem Neurons with Traumatic Brain Injury. Sleep. 2016 06 01; 39(6):1249-52.
journal title abbreviation: Sleep
publication date: 2016-06-01T00:00:00
year: 2016
type: Academic Article
type: Article
type: Document
type: Information Resource

Associate Professor
sort order: 1
type: Faculty Rank

Full Professor
sort order: 0
type: Faculty Rank

Instructor
sort order: 4
type: Faculty Rank

Authorship 186838
type: Authorship
author rank in publication: 12
linked author: Scammell, Thomas
linked information resource: Orexin (hypocretin) neurons contain dynorphin.

Orexin and the Control of Cataplexy
end date: 2012-11-30
principal investigator name: SCAMMELL, THOMAS EMERY
start date: 2000-12-01
type: Grant
sponsor award id: R01NS055367

Harvard Center on Sleep Neurobiology and Sleep Apnea (SCOR)
end date: 2008-08-31
principal investigator name: SAPER, CLIFFORD
start date: 1998-09-01
type: Grant
sponsor award id: P50HL060292

MOLECULAR MECHANISMS OF FEVER
end date: 1900-01-01
principal investigator name: SCAMMELL, THOMAS EMERY
start date: 1994-04-01
type: Grant
sponsor award id: F32NS009474

ADENOSINE AND THE PREOPTIC REGULATION OF SLEEP
end date: 2003-02-28
principal investigator name: SCAMMELL, THOMAS EMERY
start date: 1998-05-01
type: Grant
sponsor award id: K08MH001507

Mechanisms of Arousal in Sleep Apnea
end date: 2021-05-31
principal investigator name: SAPER, CLIFFORD B
start date: 2009-04-01
type: Grant
sponsor award id: P01HL095491

Circadian and Aminergic Regulation of Orexin Neurons
end date: 2007-04-30
principal investigator name: SCAMMELL, THOMAS EMERY
start date: 2001-08-15
type: Grant
sponsor award id: R01MH062589

Principal Investigator
type: Researcher Role
researcher role of: Scammell, Thomas
contributes to: ADENOSINE AND THE PREOPTIC REGULATION OF SLEEP

Principal Investigator
type: Researcher Role
researcher role of: Scammell, Thomas
contributes to: Circadian and Aminergic Regulation of Orexin Neurons

Principal Investigator
type: Researcher Role
researcher role of: Scammell, Thomas
contributes to: Orexin and the Control of Cataplexy

Co-Principal Investigator
type: Researcher Role
researcher role of: Scammell, Thomas
contributes to: Harvard Center on Sleep Neurobiology and Sleep Apnea (SCOR)

Co-Principal Investigator
type: Researcher Role
researcher role of: Scammell, Thomas
contributes to: Mechanisms of Arousal in Sleep Apnea

Principal Investigator
type: Researcher Role
researcher role of: Scammell, Thomas
contributes to: MOLECULAR MECHANISMS OF FEVER

Authorship 923829
type: Authorship
author rank in publication: 10
linked author: Scammell, Thomas
linked information resource: Dynamic GABAergic afferent modulation of AgRP neurons.

Dynamic GABAergic afferent modulation of AgRP neurons.
PubMed Identifier: 27643429
author list: Garfield AS, Shah BP, Burgess CR, Li MM, Li C, Steger JS, Madara JC, Campbell JN, Kroeger D, Scammell TE, Tannous BA, Myers MG, Andermann ML, Krashes MJ, Lowell BB
published in: Nature neuroscience
information resource reference: Dynamic GABAergic afferent modulation of AgRP neurons. Nat Neurosci. 2016 12; 19(12):1628-1635.
journal title abbreviation: Nat Neurosci
publication date: 2016-09-19T00:00:00
year: 2016
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 445841
type: Authorship
author rank in publication: 2
linked author: Scammell, Thomas
linked information resource: Hypothalamic regulation of sleep and circadian rhythms.

Authorship 63302
type: Authorship
author rank in publication: 3
linked author: Scammell, Thomas
linked information resource: Relationship of EP(1-4) prostaglandin receptors with rat hypothalamic cell groups involved in lipopolysaccharide fever responses.

Authorship 940163
type: Authorship
author rank in publication: 4
linked author: Scammell, Thomas
linked information resource: Listening to the Patient Voice in Narcolepsy: Diagnostic Delay, Disease Burden, and Treatment Efficacy.

Listening to the Patient Voice in Narcolepsy: Diagnostic Delay, Disease Burden, and Treatment Efficacy.
PubMed Identifier: 27923434
author list: Maski K, Steinhart E, Williams D, Scammell T, Flygare J, McCleary K, Gow M
published in: Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine
information resource reference: Listening to the Patient Voice in Narcolepsy: Diagnostic Delay, Disease Burden, and Treatment Efficacy. J Clin Sleep Med. 2017 Mar 15; 13(3):419-425.
journal title abbreviation: J Clin Sleep Med
publication date: 2017-03-15T00:00:00
year: 2017
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 943835
type: Authorship
author rank in publication: 7
linked author: Scammell, Thomas
linked information resource: Descending projections from the basal forebrain to the orexin neurons in mice.

Descending projections from the basal forebrain to the orexin neurons in mice.
PubMed Identifier: 27997037
author list: Agostinelli LJ, Ferrari LL, Mahoney CE, Mochizuki T, Lowell BB, Arrigoni E, Scammell TE
published in: The Journal of comparative neurology
information resource reference: Descending projections from the basal forebrain to the orexin neurons in mice. J Comp Neurol. 2017 May 01; 525(7):1668-1684.
journal title abbreviation: J Comp Neurol
publication date: 2017-02-22T00:00:00
year: 2017
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 448569
type: Authorship
author rank in publication: 1
linked author: Scammell, Thomas
linked information resource: Narcolepsy and low CSF orexin (hypocretin) concentration after a diencephalic stroke.

Authorship 946275
type: Authorship
author rank in publication: 7
linked author: Scammell, Thomas
linked information resource: Cholinergic, Glutamatergic, and GABAergic Neurons of the Pedunculopontine Tegmental Nucleus Have Distinct Effects on Sleep/Wake Behavior in Mice.

Cholinergic, Glutamatergic, and GABAergic Neurons of the Pedunculopontine Tegmental Nucleus Have Distinct Effects on Sleep/Wake Behavior in Mice.
PubMed Identifier: 28039375
author list: Kroeger D, Ferrari LL, Petit G, Mahoney CE, Fuller PM, Arrigoni E, Scammell TE
published in: The Journal of neuroscience : the official journal of the Society for Neuroscience
information resource reference: Cholinergic, Glutamatergic, and GABAergic Neurons of the Pedunculopontine Tegmental Nucleus Have Distinct Effects on Sleep/Wake Behavior in Mice. J Neurosci. 2017 02 01; 37(5):1352-1366.
journal title abbreviation: J Neurosci
publication date: 2016-12-30T00:00:00
year: 2016
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 952996
type: Authorship
author rank in publication: 7
linked author: Scammell, Thomas
linked information resource: Complementary roles of gasotransmitters CO and H2S in sleep apnea.

Complementary roles of gasotransmitters CO and H2S in sleep apnea.
PubMed Identifier: 28115703
author list: Peng YJ, Zhang X, Gridina A, Chupikova I, McCormick DL, Thomas RJ, Scammell TE, Kim G, Vasavda C, Nanduri J, Kumar GK, Semenza GL, Snyder SH, Prabhakar NR
published in: Proceedings of the National Academy of Sciences of the United States of America
information resource reference: Complementary roles of gasotransmitters CO and H2S in sleep apnea. Proc Natl Acad Sci U S A. 2017 02 07; 114(6):1413-1418.
journal title abbreviation: Proc Natl Acad Sci U S A
publication date: 2017-01-23T00:00:00
year: 2017
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 91248
type: Authorship
author rank in publication: 2
linked author: Scammell, Thomas
linked information resource: Distribution of Fos-like immunoreactivity in the rat brain following intravenous lipopolysaccharide administration.

Inhibition of nitric oxide synthase produces hypothermia and depresses lipopolysaccharide fever.
PubMed Identifier: 8770131
author list: Scammell TE, Elmquist JK, Saper CB
published in: The American journal of physiology
information resource reference: Inhibition of nitric oxide synthase produces hypothermia and depresses lipopolysaccharide fever. Am J Physiol. 1996 Aug; 271(2 Pt 2):R333-8.
journal title abbreviation: Am J Physiol
publication date: 1996-08-01T00:00:00
year: 1996
type: Academic Article
type: Article
type: Document
type: Information Resource

Ventromedial preoptic prostaglandin E2 activates fever-producing autonomic pathways.
PubMed Identifier: 8815905
author list: Scammell TE, Elmquist JK, Griffin JD, Saper CB
published in: The Journal of neuroscience : the official journal of the Society for Neuroscience
information resource reference: Ventromedial preoptic prostaglandin E2 activates fever-producing autonomic pathways. J Neurosci. 1996 Oct 01; 16(19):6246-54.
journal title abbreviation: J Neurosci
publication date: 1996-10-01T00:00:00
year: 1996
type: Academic Article
type: Article
type: Document
type: Information Resource

Fos expression in orexin neurons varies with behavioral state.
PubMed Identifier: 11222656
author list: Estabrooke IV, McCarthy MT, Ko E, Chou TC, Chemelli RM, Yanagisawa M, Saper CB, Scammell TE
published in: The Journal of neuroscience : the official journal of the Society for Neuroscience
information resource reference: Fos expression in orexin neurons varies with behavioral state. J Neurosci. 2001 Mar 01; 21(5):1656-62.
journal title abbreviation: J Neurosci
publication date: 2001-03-01T00:00:00
year: 2001
type: Academic Article
type: Article
type: Document
type: Information Resource

Orexin, drugs and motivated behaviors.
PubMed Identifier: 16189534
author list: Scammell TE, Saper CB
published in: Nature neuroscience
information resource reference: Orexin, drugs and motivated behaviors. Nat Neurosci. 2005 Oct; 8(10):1286-8.
journal title abbreviation: Nat Neurosci
publication date: 2005-10-01T00:00:00
year: 2005
type: Academic Article
type: Article
type: Document
type: Information Resource

Homeostatic, circadian, and emotional regulation of sleep.
PubMed Identifier: 16254994
author list: Saper CB, Cano G, Scammell TE
published in: The Journal of comparative neurology
information resource reference: Homeostatic, circadian, and emotional regulation of sleep. J Comp Neurol. 2005 Dec 05; 493(1):92-8.
journal title abbreviation: J Comp Neurol
publication date: 2005-12-05T00:00:00
year: 2005
type: Academic Article
type: Article
type: Document
type: Information Resource

Mechanisms of CNS response to systemic immune challenge: the febrile response.
PubMed Identifier: 9416669
author list: Elmquist JK, Scammell TE, Saper CB
published in: Trends in neurosciences
information resource reference: Mechanisms of CNS response to systemic immune challenge: the febrile response. Trends Neurosci. 1997 Dec; 20(12):565-70.
journal title abbreviation: Trends Neurosci
publication date: 1997-12-01T00:00:00
year: 1997
type: Academic Article
type: Article
type: Document
type: Information Resource

Wake-related activity of tuberomammillary neurons in rats.
PubMed Identifier: 14625060
author list: Ko EM, Estabrooke IV, McCarthy M, Scammell TE
published in: Brain research
information resource reference: Wake-related activity of tuberomammillary neurons in rats. Brain Res. 2003 Dec 05; 992(2):220-6.
journal title abbreviation: Brain Res
publication date: 2003-12-05T00:00:00
year: 2003
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 968685
type: Authorship
author rank in publication: 5
linked author: Scammell, Thomas
linked information resource: GABAergic Neurons of the Central Amygdala Promote Cataplexy.

Authorship 968623
type: Authorship
author rank in publication: 1
linked author: Scammell, Thomas
linked information resource: Neural Circuitry of Wakefulness and Sleep.

Neural Circuitry of Wakefulness and Sleep.
PubMed Identifier: 28231463
author list: Scammell TE, Arrigoni E, Lipton JO
published in: Neuron
information resource reference: Neural Circuitry of Wakefulness and Sleep. Neuron. 2017 Feb 22; 93(4):747-765.
journal title abbreviation: Neuron
publication date: 2017-02-22T00:00:00
year: 2017
type: Academic Article
type: Article
type: Document
type: Information Resource

GABAergic Neurons of the Central Amygdala Promote Cataplexy.
PubMed Identifier: 28235898
author list: Mahoney CE, Agostinelli LJ, Brooks JN, Lowell BB, Scammell TE
published in: The Journal of neuroscience : the official journal of the Society for Neuroscience
information resource reference: GABAergic Neurons of the Central Amygdala Promote Cataplexy. J Neurosci. 2017 04 12; 37(15):3995-4006.
journal title abbreviation: J Neurosci
publication date: 2017-02-24T00:00:00
year: 2017
type: Academic Article
type: Article
type: Document
type: Information Resource

Narcolepsy in orexin knockout mice: molecular genetics of sleep regulation.
PubMed Identifier: 10481909
author list: Chemelli RM, Willie JT, Sinton CM, Elmquist JK, Scammell T, Lee C, Richardson JA, Williams SC, Xiong Y, Kisanuki Y, Fitch TE, Nakazato M, Hammer RE, Saper CB, Yanagisawa M
published in: Cell
information resource reference: Narcolepsy in orexin knockout mice: molecular genetics of sleep regulation. Cell. 1999 Aug 20; 98(4):437-51.
journal title abbreviation: Cell
publication date: 1999-08-20T00:00:00
year: 1999
type: Academic Article
type: Article
type: Document
type: Information Resource

The sleep switch: hypothalamic control of sleep and wakefulness.
PubMed Identifier: 11718878
author list: Saper CB, Chou TC, Scammell TE
published in: Trends in neurosciences
information resource reference: The sleep switch: hypothalamic control of sleep and wakefulness. Trends Neurosci. 2001 Dec; 24(12):726-31.
journal title abbreviation: Trends Neurosci
publication date: 2001-12-01T00:00:00
year: 2001
type: Academic Article
type: Article
type: Document
type: Information Resource

An adenosine A2a agonist increases sleep and induces Fos in ventrolateral preoptic neurons.
PubMed Identifier: 11720788
author list: Scammell TE, Gerashchenko DY, Mochizuki T, McCarthy MT, Estabrooke IV, Sears CA, Saper CB, Urade Y, Hayaishi O
published in: Neuroscience
information resource reference: An adenosine A2a agonist increases sleep and induces Fos in ventrolateral preoptic neurons. Neuroscience. 2001; 107(4):653-63.
journal title abbreviation: Neuroscience
publication date: 2001-01-01T00:00:00
year: 2001
type: Academic Article
type: Article
type: Document
type: Information Resource

Common scale-invariant patterns of sleep-wake transitions across mammalian species.
PubMed Identifier: 15583127
author list: Lo CC, Chou T, Penzel T, Scammell TE, Strecker RE, Stanley HE, Ivanov PCh
published in: Proceedings of the National Academy of Sciences of the United States of America
information resource reference: Common scale-invariant patterns of sleep-wake transitions across mammalian species. Proc Natl Acad Sci U S A. 2004 Dec 14; 101(50):17545-8.
journal title abbreviation: Proc Natl Acad Sci U S A
publication date: 2004-12-06T00:00:00
year: 2004
type: Academic Article
type: Article
type: Document
type: Information Resource

Intravenous lipopolysaccharide induces cyclooxygenase 2-like immunoreactivity in rat brain perivascular microglia and meningeal macrophages.
PubMed Identifier: 9130663
author list: Elmquist JK, Breder CD, Sherin JE, Scammell TE, Hickey WF, Dewitt D, Saper CB
published in: The Journal of comparative neurology
information resource reference: Intravenous lipopolysaccharide induces cyclooxygenase 2-like immunoreactivity in rat brain perivascular microglia and meningeal macrophages. J Comp Neurol. 1997 May 05; 381(2):119-29.
journal title abbreviation: J Comp Neurol
publication date: 1997-05-05T00:00:00
year: 1997
type: Academic Article
type: Article
type: Document
type: Information Resource

Cerebral deep venous thrombosis presenting as acute micrographia and hypophonia.
PubMed Identifier: 10680819
author list: Murray BJ, Llinas R, Caplan LR, Scammell T, Pascual-Leone A
published in: Neurology
information resource reference: Cerebral deep venous thrombosis presenting as acute micrographia and hypophonia. Neurology. 2000 Feb 08; 54(3):751-3.
journal title abbreviation: Neurology
publication date: 2000-02-08T00:00:00
year: 2000
type: Academic Article
type: Article
type: Document
type: Information Resource

Hypothalamic arousal regions are activated during modafinil-induced wakefulness.
PubMed Identifier: 11069971
author list: Scammell TE, Estabrooke IV, McCarthy MT, Chemelli RM, Yanagisawa M, Miller MS, Saper CB
published in: The Journal of neuroscience : the official journal of the Society for Neuroscience
information resource reference: Hypothalamic arousal regions are activated during modafinil-induced wakefulness. J Neurosci. 2000 Nov 15; 20(22):8620-8.
journal title abbreviation: J Neurosci
publication date: 2000-11-15T00:00:00
year: 2000
type: Academic Article
type: Article
type: Document
type: Information Resource

Severe acute disseminated encephalomyelitis with normal MRI at presentation.
PubMed Identifier: 11071514
author list: Murray BJ, Apetauerova D, Scammell TE
published in: Neurology
information resource reference: Severe acute disseminated encephalomyelitis with normal MRI at presentation. Neurology. 2000 Oct 24; 55(8):1237-8.
journal title abbreviation: Neurology
publication date: 2000-10-24T00:00:00
year: 2000
type: Academic Article
type: Article
type: Document
type: Information Resource

Orexin (hypocretin) neurons contain dynorphin.
PubMed Identifier: 11567079
author list: Chou TC, Lee CE, Lu J, Elmquist JK, Hara J, Willie JT, Beuckmann CT, Chemelli RM, Sakurai T, Yanagisawa M, Saper CB, Scammell TE
published in: The Journal of neuroscience : the official journal of the Society for Neuroscience
information resource reference: Orexin (hypocretin) neurons contain dynorphin. J Neurosci. 2001 Oct 01; 21(19):RC168.
journal title abbreviation: J Neurosci
publication date: 2001-10-01T00:00:00
year: 2001
type: Academic Article
type: Article
type: Document
type: Information Resource

The frustrating and mostly fruitless search for an autoimmune cause of narcolepsy.
PubMed Identifier: 16774147
author list: Scammell TE
published in: Sleep
information resource reference: The frustrating and mostly fruitless search for an autoimmune cause of narcolepsy. Sleep. 2006 May; 29(5):601-2.
journal title abbreviation: Sleep
publication date: 2006-05-01T00:00:00
year: 2006
type: Academic Article
type: Article
type: Document
type: Information Resource

Distribution of Fos-like immunoreactivity in the rat brain following intravenous lipopolysaccharide administration.
PubMed Identifier: 8835720
author list: Elmquist JK, Scammell TE, Jacobson CD, Saper CB
published in: The Journal of comparative neurology
information resource reference: Distribution of Fos-like immunoreactivity in the rat brain following intravenous lipopolysaccharide administration. J Comp Neurol. 1996 Jul 15; 371(1):85-103.
journal title abbreviation: J Comp Neurol
publication date: 1996-07-15T00:00:00
year: 1996
type: Academic Article
type: Article
type: Document
type: Information Resource

Mistaken diagnosis of psychogenic gait disorder in a man with status cataplecticus ("limp man syndrome").
PubMed Identifier: 15254948
author list: Simon DK, Nishino S, Scammell TE
published in: Movement disorders : official journal of the Movement Disorder Society
information resource reference: Mistaken diagnosis of psychogenic gait disorder in a man with status cataplecticus ("limp man syndrome"). Mov Disord. 2004 Jul; 19(7):838-840.
journal title abbreviation: Mov Disord
publication date: 2004-07-01T00:00:00
year: 2004
type: Academic Article
type: Article
type: Document
type: Information Resource

Melanopsin in cells of origin of the retinohypothalamic tract.
PubMed Identifier: 11713469
author list: Gooley JJ, Lu J, Chou TC, Scammell TE, Saper CB
published in: Nature neuroscience
information resource reference: Melanopsin in cells of origin of the retinohypothalamic tract. Nat Neurosci. 2001 Dec; 4(12):1165.
journal title abbreviation: Nat Neurosci
publication date: 2001-12-01T00:00:00
year: 2001
type: Academic Article
type: Article
type: Document
type: Information Resource

Polymorphisms in hypocretin/orexin pathway genes and narcolepsy.
PubMed Identifier: 11723285
author list: Olafsdóttir BR, Rye DB, Scammell TE, Matheson JK, Stefánsson K, Gulcher JR
published in: Neurology
information resource reference: Polymorphisms in hypocretin/orexin pathway genes and narcolepsy. Neurology. 2001 Nov 27; 57(10):1896-9.
journal title abbreviation: Neurology
publication date: 2001-11-27T00:00:00
year: 2001
type: Academic Article
type: Article
type: Document
type: Information Resource

Inter-hemispheric oscillations in human sleep.
PubMed Identifier: 23144920
author list: Imbach LL, Werth E, Kallweit U, Sarnthein J, Scammell TE, Baumann CR
published in: PloS one
information resource reference: Inter-hemispheric oscillations in human sleep. PLoS One. 2012; 7(11):e48660.
journal title abbreviation: PLoS One
publication date: 2012-11-07T00:00:00
year: 2012
type: Academic Article
type: Article
type: Document
type: Information Resource

Microinjection of a cyclooxygenase inhibitor into the anteroventral preoptic region attenuates LPS fever.
PubMed Identifier: 9530246
author list: Scammell TE, Griffin JD, Elmquist JK, Saper CB
published in: The American journal of physiology
information resource reference: Microinjection of a cyclooxygenase inhibitor into the anteroventral preoptic region attenuates LPS fever. Am J Physiol. 1998 03; 274(3):R783-9.
journal title abbreviation: Am J Physiol
publication date: 1998-03-01T00:00:00
year: 1998
type: Academic Article
type: Article
type: Document
type: Information Resource

Narcolepsy and low CSF orexin (hypocretin) concentration after a diencephalic stroke.
PubMed Identifier: 11425947
author list: Scammell TE, Nishino S, Mignot E, Saper CB
published in: Neurology
information resource reference: Narcolepsy and low CSF orexin (hypocretin) concentration after a diencephalic stroke. Neurology. 2001 Jun 26; 56(12):1751-3.
journal title abbreviation: Neurology
publication date: 2001-06-26T00:00:00
year: 2001
type: Academic Article
type: Article
type: Document
type: Information Resource

Effects of adenosine on gabaergic synaptic inputs to identified ventrolateral preoptic neurons.
PubMed Identifier: 12831851
author list: Chamberlin NL, Arrigoni E, Chou TC, Scammell TE, Greene RW, Saper CB
published in: Neuroscience
information resource reference: Effects of adenosine on gabaergic synaptic inputs to identified ventrolateral preoptic neurons. Neuroscience. 2003; 119(4):913-8.
journal title abbreviation: Neuroscience
publication date: 2003-01-01T00:00:00
year: 2003
type: Academic Article
type: Article
type: Document
type: Information Resource

Focal deletion of the adenosine A1 receptor in adult mice using an adeno-associated viral vector.
PubMed Identifier: 12843280
author list: Scammell TE, Arrigoni E, Thompson MA, Ronan PJ, Saper CB, Greene RW
published in: The Journal of neuroscience : the official journal of the Society for Neuroscience
information resource reference: Focal deletion of the adenosine A1 receptor in adult mice using an adeno-associated viral vector. J Neurosci. 2003 Jul 02; 23(13):5762-70.
journal title abbreviation: J Neurosci
publication date: 2003-07-02T00:00:00
year: 2003
type: Academic Article
type: Article
type: Document
type: Information Resource

Effects of vagus nerve stimulation on respiration during sleep.
PubMed Identifier: 11673612
author list: Murray BJ, Matheson JK, Scammell TE
published in: Neurology
information resource reference: Effects of vagus nerve stimulation on respiration during sleep. Neurology. 2001 Oct 23; 57(8):1523-4.
journal title abbreviation: Neurology
publication date: 2001-10-23T00:00:00
year: 2001
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 981927
type: Authorship
author rank in publication: 4
linked author: Scammell, Thomas
linked information resource: Cataplexy and Its Mimics: Clinical Recognition and Management.

Authorship 981459
type: Authorship
author rank in publication: 6
linked author: Scammell, Thomas
linked information resource: Decreased alertness due to sleep loss increases pain sensitivity in mice.

Cataplexy and Its Mimics: Clinical Recognition and Management.
PubMed Identifier: 28478511
author list: Pillen S, Pizza F, Dhondt K, Scammell TE, Overeem S
published in: Current treatment options in neurology
information resource reference: Cataplexy and Its Mimics: Clinical Recognition and Management. Curr Treat Options Neurol. 2017 Jun; 19(6):23.
journal title abbreviation: Curr Treat Options Neurol
publication date: 2017-06-01T00:00:00
year: 2017
type: Academic Article
type: Article
type: Document
type: Information Resource

Decreased alertness due to sleep loss increases pain sensitivity in mice.
PubMed Identifier: 28481358
author list: Alexandre C, Latremoliere A, Ferreira A, Miracca G, Yamamoto M, Scammell TE, Woolf CJ
published in: Nature medicine
information resource reference: Decreased alertness due to sleep loss increases pain sensitivity in mice. Nat Med. 2017 Jun; 23(6):768-774.
journal title abbreviation: Nat Med
publication date: 2017-05-08T00:00:00
year: 2017
type: Academic Article
type: Article
type: Document
type: Information Resource

Concomitant loss of dynorphin, NARP, and orexin in narcolepsy.
PubMed Identifier: 16247044
author list: Crocker A, España RA, Papadopoulou M, Saper CB, Faraco J, Sakurai T, Honda M, Mignot E, Scammell TE
published in: Neurology
information resource reference: Concomitant loss of dynorphin, NARP, and orexin in narcolepsy. Neurology. 2005 Oct 25; 65(8):1184-8.
journal title abbreviation: Neurology
publication date: 2005-09-14T00:00:00
year: 2005
type: Academic Article
type: Article
type: Document
type: Information Resource

Orexins: looking forward to sleep, back at addiction.
PubMed Identifier: 17290266
author list: Scammell TE, Saper CB
published in: Nature medicine
information resource reference: Orexins: looking forward to sleep, back at addiction. Nat Med. 2007 Feb; 13(2):126-8.
journal title abbreviation: Nat Med
publication date: 2007-02-01T00:00:00
year: 2007
type: Academic Article
type: Article
type: Document
type: Information Resource

Critical role of dorsomedial hypothalamic nucleus in a wide range of behavioral circadian rhythms.
PubMed Identifier: 14627654
author list: Chou TC, Scammell TE, Gooley JJ, Gaus SE, Saper CB, Lu J
published in: The Journal of neuroscience : the official journal of the Society for Neuroscience
information resource reference: Critical role of dorsomedial hypothalamic nucleus in a wide range of behavioral circadian rhythms. J Neurosci. 2003 Nov 19; 23(33):10691-702.
journal title abbreviation: J Neurosci
publication date: 2003-11-19T00:00:00
year: 2003
type: Academic Article
type: Article
type: Document
type: Information Resource

Running promotes wakefulness and increases cataplexy in orexin knockout mice.
PubMed Identifier: 18041476
author list: España RA, McCormack SL, Mochizuki T, Scammell TE
published in: Sleep
information resource reference: Running promotes wakefulness and increases cataplexy in orexin knockout mice. Sleep. 2007 Nov; 30(11):1417-25.
journal title abbreviation: Sleep
publication date: 2007-11-01T00:00:00
year: 2007
type: Academic Article
type: Article
type: Document
type: Information Resource

Deletion of presynaptic adenosine A1 receptors impairs the recovery of synaptic transmission after hypoxia.
PubMed Identifier: 15837119
author list: Arrigoni E, Crocker AJ, Saper CB, Greene RW, Scammell TE
published in: Neuroscience
information resource reference: Deletion of presynaptic adenosine A1 receptors impairs the recovery of synaptic transmission after hypoxia. Neuroscience. 2005; 132(3):575-80.
journal title abbreviation: Neuroscience
publication date: 2005-01-01T00:00:00
year: 2005
type: Academic Article
type: Article
type: Document
type: Information Resource

Orexin receptors: pharmacology and therapeutic opportunities.
PubMed Identifier: 21034217
author list: Scammell TE, Winrow CJ
published in: Annual review of pharmacology and toxicology
information resource reference: Orexin receptors: pharmacology and therapeutic opportunities. Annu Rev Pharmacol Toxicol. 2011; 51:243-66.
journal title abbreviation: Annu Rev Pharmacol Toxicol
publication date: 2011-01-01T00:00:00
year: 2011
type: Academic Article
type: Article
type: Document
type: Information Resource

Diurnal variation in CSF orexin-A in healthy male subjects.
PubMed Identifier: 16553014
author list: Grady SP, Nishino S, Czeisler CA, Hepner D, Scammell TE
published in: Sleep
information resource reference: Diurnal variation in CSF orexin-A in healthy male subjects. Sleep. 2006 Mar; 29(3):295-7.
journal title abbreviation: Sleep
publication date: 2006-03-01T00:00:00
year: 2006
type: Academic Article
type: Article
type: Document
type: Information Resource

Cano, Christopher
eCommons Login: CAA23
first name: Christopher
last name: Cano
full name: Christopher Abel Cano, M.D.
has faculty rank: Instructor
Person ID: 161916
person in primary position: Instructor in Neurology
type: Agent
type: Person
preferred title: Instructor in Neurology

Orexin neurons are necessary for the circadian control of REM sleep.
PubMed Identifier: 19750917
author list: Kantor S, Mochizuki T, Janisiewicz AM, Clark E, Nishino S, Scammell TE
published in: Sleep
information resource reference: Orexin neurons are necessary for the circadian control of REM sleep. Sleep. 2009 Sep; 32(9):1127-34.
journal title abbreviation: Sleep
publication date: 2009-09-01T00:00:00
year: 2009
type: Academic Article
type: Article
type: Document
type: Information Resource

330 Brookline Ave
type: Address
address line 1: Beth Israel Deaconess Medical Center
address line 2: C L S 705
address line 3: 330 Brookline Ave
city: Boston
postal code: 02215
state or province: MA

Hyperthermia induces c-fos expression in the preoptic area.
PubMed Identifier: 8374760
author list: Scammell TE, Price KJ, Sagar SM
published in: Brain research
information resource reference: Hyperthermia induces c-fos expression in the preoptic area. Brain Res. 1993 Aug 06; 618(2):303-7.
journal title abbreviation: Brain Res
publication date: 1993-08-06T00:00:00
year: 1993
type: Academic Article
type: Article
type: Document
type: Information Resource

Feeding-elicited cataplexy in orexin knockout mice.
PubMed Identifier: 19362119
author list: Clark EL, Baumann CR, Cano G, Scammell TE, Mochizuki T
published in: Neuroscience
information resource reference: Feeding-elicited cataplexy in orexin knockout mice. Neuroscience. 2009 Jul 21; 161(4):970-7.
journal title abbreviation: Neuroscience
publication date: 2009-04-08T00:00:00
year: 2009
type: Academic Article
type: Article
type: Document
type: Information Resource

Loss of hypocretin (orexin) neurons with traumatic brain injury.
PubMed Identifier: 19847903
author list: Baumann CR, Bassetti CL, Valko PO, Haybaeck J, Keller M, Clark E, Stocker R, Tolnay M, Scammell TE
published in: Annals of neurology
information resource reference: Loss of hypocretin (orexin) neurons with traumatic brain injury. Ann Neurol. 2009 Oct; 66(4):555-9.
journal title abbreviation: Ann Neurol
publication date: 2009-10-01T00:00:00
year: 2009
type: Academic Article
type: Article
type: Document
type: Information Resource

Narcolepsy as an adverse event following immunization: case definition and guidelines for data collection, analysis and presentation.
PubMed Identifier: 23246545
author list: Poli F, Overeem S, Lammers GJ, Plazzi G, Lecendreux M, Bassetti CL, Dauvilliers Y, Keene D, Khatami R, Li Y, Mayer G, Nohynek H, Pahud B, Paiva T, Partinen M, Scammell TE, Shimabukuro T, Sturkenboom M, van Dinther K, Wiznitzer M, Bonhoeffer J
published in: Vaccine
information resource reference: Narcolepsy as an adverse event following immunization: case definition and guidelines for data collection, analysis and presentation. Vaccine. 2013 Jan 30; 31(6):994-1007.
journal title abbreviation: Vaccine
publication date: 2012-12-16T00:00:00
year: 2012
type: Academic Article
type: Article
type: Document
type: Information Resource

Neural circuitry engaged by prostaglandins during the sickness syndrome.
PubMed Identifier: 22837039
author list: Saper CB, Romanovsky AA, Scammell TE
published in: Nature neuroscience
information resource reference: Neural circuitry engaged by prostaglandins during the sickness syndrome. Nat Neurosci. 2012 Jul 26; 15(8):1088-95.
journal title abbreviation: Nat Neurosci
publication date: 2012-07-26T00:00:00
year: 2012
type: Academic Article
type: Article
type: Document
type: Information Resource

Activation of ventrolateral preoptic neurons by the somnogen prostaglandin D2.
PubMed Identifier: 9636223
author list: Scammell T, Gerashchenko D, Urade Y, Onoe H, Saper C, Hayaishi O
published in: Proceedings of the National Academy of Sciences of the United States of America
information resource reference: Activation of ventrolateral preoptic neurons by the somnogen prostaglandin D2. Proc Natl Acad Sci U S A. 1998 Jun 23; 95(13):7754-9.
journal title abbreviation: Proc Natl Acad Sci U S A
publication date: 1998-06-23T00:00:00
year: 1998
type: Academic Article
type: Article
type: Document
type: Information Resource

Abnormal sleep/wake dynamics in orexin knockout mice.
PubMed Identifier: 20337187
author list: Diniz Behn CG, Klerman EB, Mochizuki T, Lin SC, Scammell TE
published in: Sleep
information resource reference: Abnormal sleep/wake dynamics in orexin knockout mice. Sleep. 2010 Mar; 33(3):297-306.
journal title abbreviation: Sleep
publication date: 2010-03-01T00:00:00
year: 2010
type: Academic Article
type: Article
type: Document
type: Information Resource

Regulation of daily locomotor activity and sleep by hypothalamic EGF receptor signaling.
PubMed Identifier: 11752569
author list: Kramer A, Yang FC, Snodgrass P, Li X, Scammell TE, Davis FC, Weitz CJ
published in: Science (New York, N.Y.)
information resource reference: Regulation of daily locomotor activity and sleep by hypothalamic EGF receptor signaling. Science. 2001 Dec 21; 294(5551):2511-5.
journal title abbreviation: Science
publication date: 2001-12-21T00:00:00
year: 2001
type: Academic Article
type: Article
type: Document
type: Information Resource

Elevated body temperature during sleep in orexin knockout mice.
PubMed Identifier: 16556901
author list: Mochizuki T, Klerman EB, Sakurai T, Scammell TE
published in: American journal of physiology. Regulatory, integrative and comparative physiology
information resource reference: Elevated body temperature during sleep in orexin knockout mice. Am J Physiol Regul Integr Comp Physiol. 2006 Sep; 291(3):R533-40.
journal title abbreviation: Am J Physiol Regul Integr Comp Physiol
publication date: 2006-09-01T00:00:00
year: 2006
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1018540
type: Authorship
author rank in publication: 4
linked author: Scammell, Thomas
linked information resource: Dysregulation of Sleep Behavioral States in Narcolepsy.

Dysregulation of Sleep Behavioral States in Narcolepsy.
PubMed Identifier: 29029348
author list: Schoch SF, Werth E, Poryazova R, Scammell TE, Baumann CR, Imbach LL
published in: Sleep
information resource reference: Dysregulation of Sleep Behavioral States in Narcolepsy. Sleep. 2017 12 01; 40(12).
journal title abbreviation: Sleep
publication date: 2017-12-01T00:00:00
year: 2017
type: Academic Article
type: Article
type: Document
type: Information Resource

Afferents to the orexin neurons of the rat brain.
PubMed Identifier: 16374809
author list: Yoshida K, McCormack S, España RA, Crocker A, Scammell TE
published in: The Journal of comparative neurology
information resource reference: Afferents to the orexin neurons of the rat brain. J Comp Neurol. 2006 Feb 10; 494(5):845-61.
journal title abbreviation: J Comp Neurol
publication date: 2006-02-10T00:00:00
year: 2006
type: Academic Article
type: Article
type: Document
type: Information Resource

Modafinil: a drug in search of a mechanism.
PubMed Identifier: 14998230
author list: Saper CB, Scammell TE
published in: Sleep
information resource reference: Modafinil: a drug in search of a mechanism. Sleep. 2004 Feb 01; 27(1):11-2.
journal title abbreviation: Sleep
publication date: 2004-02-01T00:00:00
year: 2004
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1025472
type: Authorship
author rank in publication: 4
linked author: Scammell, Thomas
linked information resource: Insight Into Reduction of Wakefulness by Suvorexant in Patients With Insomnia: Analysis of Wake Bouts.

Insight Into Reduction of Wakefulness by Suvorexant in Patients With Insomnia: Analysis of Wake Bouts.
PubMed Identifier: 29112763
author list: Svetnik V, Snyder ES, Tao P, Scammell TE, Roth T, Lines C, Herring WJ
published in: Sleep
information resource reference: Insight Into Reduction of Wakefulness by Suvorexant in Patients With Insomnia: Analysis of Wake Bouts. Sleep. 2018 01 01; 41(1).
journal title abbreviation: Sleep
publication date: 2018-01-01T00:00:00
year: 2018
type: Academic Article
type: Article
type: Document
type: Information Resource

Parkinson's disease, sleepiness and hypocretin/orexin.
PubMed Identifier: 17898005
author list: Baumann CR, Scammell TE, Bassetti CL
published in: Brain : a journal of neurology
information resource reference: Parkinson's disease, sleepiness and hypocretin/orexin. Brain. 2008 Mar; 131(Pt 3):e91.
journal title abbreviation: Brain
publication date: 2007-09-26T00:00:00
year: 2007
type: Academic Article
type: Article
type: Document
type: Information Resource

Do enteric neurons make hypocretin?
PubMed Identifier: 18191238
author list: Baumann CR, Clark EL, Pedersen NP, Hecht JL, Scammell TE
published in: Regulatory peptides
information resource reference: Do enteric neurons make hypocretin? Regul Pept. 2008 Apr 10; 147(1-3):1-3.
journal title abbreviation: Regul Pept
publication date: 2007-12-14T00:00:00
year: 2007
type: Academic Article
type: Article
type: Document
type: Information Resource

Mahoney, Carrie
eCommons Login: CM352
first name: Carrie
last name: Mahoney
full name: Carrie Mahoney, Ph.D.
has faculty rank: Instructor
Person ID: 165538
person in primary position: Instructor in Neurology
type: Agent
type: Person
preferred title: Instructor in Neurology

A consensus definition of cataplexy in mouse models of narcolepsy.
PubMed Identifier: 19189786
author list: Scammell TE, Willie JT, Guilleminault C, Siegel JM
published in: Sleep
information resource reference: A consensus definition of cataplexy in mouse models of narcolepsy. Sleep. 2009 Jan; 32(1):111-6.
journal title abbreviation: Sleep
publication date: 2009-01-01T00:00:00
year: 2009
type: Academic Article
type: Article
type: Document
type: Information Resource

Sleep neurobiology from a clinical perspective.
PubMed Identifier: 21731134
author list: España RA, Scammell TE
published in: Sleep
information resource reference: Sleep neurobiology from a clinical perspective. Sleep. 2011 Jul 01; 34(7):845-58.
journal title abbreviation: Sleep
publication date: 2011-07-01T00:00:00
year: 2011
type: Academic Article
type: Article
type: Document
type: Information Resource

Afferents to the ventrolateral preoptic nucleus.
PubMed Identifier: 11826126
author list: Chou TC, Bjorkum AA, Gaus SE, Lu J, Scammell TE, Saper CB
published in: The Journal of neuroscience : the official journal of the Society for Neuroscience
information resource reference: Afferents to the ventrolateral preoptic nucleus. J Neurosci. 2002 Feb 01; 22(3):977-90.
journal title abbreviation: J Neurosci
publication date: 2002-02-01T00:00:00
year: 2002
type: Academic Article
type: Article
type: Document
type: Information Resource

Behavioral state instability in orexin knock-out mice.
PubMed Identifier: 15254084
author list: Mochizuki T, Crocker A, McCormack S, Yanagisawa M, Sakurai T, Scammell TE
published in: The Journal of neuroscience : the official journal of the Society for Neuroscience
information resource reference: Behavioral state instability in orexin knock-out mice. J Neurosci. 2004 Jul 14; 24(28):6291-300.
journal title abbreviation: J Neurosci
publication date: 2004-07-14T00:00:00
year: 2004
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 100377
type: Authorship
author rank in publication: 3
linked author: Scammell, Thomas
linked information resource: Homeostatic, circadian, and emotional regulation of sleep.

Relationship of EP(1-4) prostaglandin receptors with rat hypothalamic cell groups involved in lipopolysaccharide fever responses.
PubMed Identifier: 11058222
author list: Oka T, Oka K, Scammell TE, Lee C, Kelly JF, Nantel F, Elmquist JK, Saper CB
published in: The Journal of comparative neurology
information resource reference: Relationship of EP(1-4) prostaglandin receptors with rat hypothalamic cell groups involved in lipopolysaccharide fever responses. J Comp Neurol. 2000 Dec 04; 428(1):20-32.
journal title abbreviation: J Comp Neurol
publication date: 2000-12-04T00:00:00
year: 2000
type: Academic Article
type: Article
type: Document
type: Information Resource