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Intracochlear drug delivery systems: a novel approach whose time has come. Expert Opin Drug Deliv. 2018 04; 15(4):319-324.
Intracochlear drug delivery systems: a novel approach whose time has come.
Khademhosseini A, Bettinger C, Karp JM, Yeh J, Ling Y, Borenstein J, Fukuda J, Langer R
Journal of biomaterials science. Polymer edition
Interplay of biomaterials and micro-scale technologies for advancing biomedical applications. J Biomater Sci Polym Ed. 2006; 17(11):1221-40.
Interplay of biomaterials and micro-scale technologies for advancing biomedical applications.
Rodby RA, Chiou CF, Borenstein J, Smitten A, Sengupta N, Palmer AJ, Roze S, Annemans L, Simon TA, Chen RS, Lewis EJ
The cost-effectiveness of irbesartan in the treatment of hypertensive patients with type 2 diabetic nephropathy. Clin Ther. 2003 Jul; 25(7):2102-19.
The cost-effectiveness of irbesartan in the treatment of hypertensive patients with type 2 diabetic nephropathy.
Ayoob AM, Peppi M, Tandon V, Langer R, Borenstein JT
A fluorescence-based imaging approach to pharmacokinetic analysis of intracochlear drug delivery. Hear Res. 2018 10; 368:41-48.
A fluorescence-based imaging approach to pharmacokinetic analysis of intracochlear drug delivery.
Hsu WM, Carraro A, Kulig KM, Miller ML, Kaazempur-Mofrad M, Weinberg E, Entabi F, Albadawi H, Watkins MT, Borenstein JT, Vacanti JP, Neville C
Liver-assist device with a microfluidics-based vascular bed in an animal model. Ann Surg. 2010 Aug; 252(2):351-7.
Liver-assist device with a microfluidics-based vascular bed in an animal model.
Transport and shear in a microfluidic membrane bilayer device for cell culture. Biomicrofluidics. 2011 Jun; 5(2):22213.
Transport and shear in a microfluidic membrane bilayer device for cell culture.
Gerecht S, Bettinger CJ, Zhang Z, Borenstein JT, Vunjak-Novakovic G, Langer R
The effect of actin disrupting agents on contact guidance of human embryonic stem cells. Biomaterials. 2007 Oct; 28(28):4068-77.
The effect of actin disrupting agents on contact guidance of human embryonic stem cells.
Fiering J, Mescher MJ, Leary Swan EE, Holmboe ME, Murphy BA, Chen Z, Peppi M, Sewell WF, McKenna MJ, Kujawa SG, Borenstein JT
Local drug delivery with a self-contained, programmable, microfluidic system. Biomed Microdevices. 2009 Jun; 11(3):571-8.
Local drug delivery with a self-contained, programmable, microfluidic system.
Du Y, Shim J, Vidula M, Hancock MJ, Lo E, Chung BG, Borenstein JT, Khabiry M, Cropek DM, Khademhosseini A
Rapid generation of spatially and temporally controllable long-range concentration gradients in a microfluidic device. Lab Chip. 2009 Mar 21; 9(6):761-7.
Rapid generation of spatially and temporally controllable long-range concentration gradients in a microfluidic device.
Kendler DL, Bessette L, Hill CD, Gold DT, Horne R, Varon SF, Borenstein J, Wang H, Man HS, Wagman RB, Siddhanti S, Macarios D, Bone HG
Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA
Preference and satisfaction with a 6-month subcutaneous injection versus a weekly tablet for treatment of low bone mass. Osteoporos Int. 2010 May; 21(5):837-46.
Preference and satisfaction with a 6-month subcutaneous injection versus a weekly tablet for treatment of low bone mass.
Moore N, Doty D, Zielstorff M, Kariv I, Moy LY, Gimbel A, Chevillet JR, Lowry N, Santos J, Mott V, Kratchman L, Lau T, Addona G, Chen H, Borenstein JT
A multiplexed microfluidic system for evaluation of dynamics of immune-tumor interactions. Lab Chip. 2018 06 26; 18(13):1844-1858.
A multiplexed microfluidic system for evaluation of dynamics of immune-tumor interactions.
Intracochlear drug delivery systems. Expert Opin Drug Deliv. 2011 Sep; 8(9):1161-74.
Khademhosseini A, Yeh J, Eng G, Karp J, Kaji H, Borenstein J, Farokhzad OC, Langer R
Cell docking inside microwells within reversibly sealed microfluidic channels for fabricating multiphenotype cell arrays. Lab Chip. 2005 Dec; 5(12):1380-6.
Cell docking inside microwells within reversibly sealed microfluidic channels for fabricating multiphenotype cell arrays.
Carlen ET, Weinberg MS, Zapata AM, Borenstein JT
A micromachined surface stress sensor with electronic readout. Rev Sci Instrum. 2008 Jan; 79(1):015106.
A micromachined surface stress sensor with electronic readout.
Pararas EE, Chen Z, Fiering J, Mescher MJ, Kim ES, McKenna MJ, Kujawa SG, Borenstein JT, Sewell WF
Journal of controlled release : official journal of the Controlled Release Society
Kinetics of reciprocating drug delivery to the inner ear. J Control Release. 2011 Jun 10; 152(2):270-7.
Kinetics of reciprocating drug delivery to the inner ear.
Eda H, Kulig KM, Steiner TA, Shimada H, Patel K, Park E, Kim ES, Borenstein JT, Neville CM, Keller BT
A nanofiber membrane maintains the quiescent phenotype of hepatic stellate cells. Dig Dis Sci. 2012 May; 57(5):1152-62.
A nanofiber membrane maintains the quiescent phenotype of hepatic stellate cells.
Acting together, bacterial clusters initiate coagulation. Nat Chem Biol. 2008 Dec; 4(12):718-9.
Acting together, bacterial clusters initiate coagulation.
Drug metabolism and disposition: the biological fate of chemicals
Microfluidic Cell Culture Platforms to Capture Hepatic Physiology and Complex Cellular Interactions. Drug Metab Dispos. 2018 11; 46(11):1638-1646.
Microfluidic Cell Culture Platforms to Capture Hepatic Physiology and Complex Cellular Interactions.
Kniazeva T, Hsiao JC, Charest JL, Borenstein JT
A microfluidic respiratory assist device with high gas permeance for artificial lung applications. Biomed Microdevices. 2011 Apr; 13(2):315-23.
A microfluidic respiratory assist device with high gas permeance for artificial lung applications.
Hoganson DM, Anderson JL, Weinberg EF, Swart E, Swart EJ, Orrick BK, Borenstein JT, Vacanti JP
The Journal of thoracic and cardiovascular surgery
Branched vascular network architecture: a new approach to lung assist device technology. J Thorac Cardiovasc Surg. 2010 Nov; 140(5):990-5.
Branched vascular network architecture: a new approach to lung assist device technology.
Angewandte Chemie (International ed. in English)
Engineering substrate topography at the micro- and nanoscale to control cell function. Angew Chem Int Ed Engl. 2009; 48(30):5406-15.
Engineering substrate topography at the micro- and nanoscale to control cell function.
McCall AA, Swan EE, Borenstein JT, Sewell WF, Kujawa SG, McKenna MJ
Drug delivery for treatment of inner ear disease: current state of knowledge. Ear Hear. 2010 Apr; 31(2):156-65.
Drug delivery for treatment of inner ear disease: current state of knowledge.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences
Intracochlear drug delivery: Fluorescent tracer evaluation for quantification of distribution in the cochlear partition. Eur J Pharm Sci. 2019 Jan 01; 126:49-58.
Intracochlear drug delivery: Fluorescent tracer evaluation for quantification of distribution in the cochlear partition.
Bettinger CJ, Kulig KM, Vacanti JP, Langer R, Borenstein JT
Nanofabricated collagen-inspired synthetic elastomers for primary rat hepatocyte culture. Tissue Eng Part A. 2009 Jun; 15(6):1321-9.
Nanofabricated collagen-inspired synthetic elastomers for primary rat hepatocyte culture.
Fidkowski C, Kaazempur-Mofrad MR, Borenstein J, Vacanti JP, Langer R, Wang Y
Endothelialized microvasculature based on a biodegradable elastomer. Tissue Eng. 2005 Jan-Feb; 11(1-2):302-9.
Endothelialized microvasculature based on a biodegradable elastomer.
Engineering tissue with BioMEMS. IEEE Pulse. 2011 Nov; 2(6):28-34.
Beckwith AL, Velásquez-García LF, Borenstein JT
Microfluidic Model for Evaluation of Immune Checkpoint Inhibitors in Human Tumors. Adv Healthc Mater. 2019 06; 8(11):e1900289.
Microfluidic Model for Evaluation of Immune Checkpoint Inhibitors in Human Tumors.
John Homans Professor of Surgery, Emeritus
Judah Folkman Professor of Vascular Biology in the Department of Surgery
Helen Andrus Benedict Professor of Surgery
Professor of Otolaryngology Head and Neck Surgery, Emeritus
Harriet Ryan Albee Professor of Medicine
Moore N, Chevillet JR, Healey LJ, McBrine C, Doty D, Santos J, Teece B, Truslow J, Mott V, Hsi P, Tandon V, Borenstein JT, Balestrini J, Kotz K
A Microfluidic Device to Enhance Viral Transduction Efficiency During Manufacture of Engineered Cellular Therapies. Sci Rep. 2019 10 22; 9(1):15101.
A Microfluidic Device to Enhance Viral Transduction Efficiency During Manufacture of Engineered Cellular Therapies.
Doty DT, Schueler J, Mott VL, Bryan CM, Moore NF, Ho JC, Borenstein JT
International journal of molecular sciences
Modeling Immune Checkpoint Inhibitor Efficacy in Syngeneic Mouse Tumors in an Ex Vivo Immuno-Oncology Dynamic Environment. Int J Mol Sci. 2020 Sep 04; 21(18).
Modeling Immune Checkpoint Inhibitor Efficacy in Syngeneic Mouse Tumors in an Ex Vivo Immuno-Oncology Dynamic Environment.
Gimbel AA, Hsiao JC, Kim ES, Lewis DJ, Risoleo TF, Urban JN, Borenstein JT
A high gas transfer efficiency microfluidic oxygenator for extracorporeal respiratory assist applications in critical care medicine. Artif Organs. 2021 Aug; 45(8):E247-E264.
A high gas transfer efficiency microfluidic oxygenator for extracorporeal respiratory assist applications in critical care medicine.
Rogers MT, Gard AL, Gaibler R, Mulhern TJ, Strelnikov R, Azizgolshani H, Cain BP, Isenberg BC, Haroutunian NJ, Raustad NE, Keegan PM, Lech MP, Tomlinson L, Borenstein JT, Charest JL, Williams C
A high-throughput microfluidic bilayer co-culture platform to study endothelial-pericyte interactions. Sci Rep. 2021 06 09; 11(1):12225.
A high-throughput microfluidic bilayer co-culture platform to study endothelial-pericyte interactions.
Gard AL, Luu RJ, Miller CR, Maloney R, Cain BP, Marr EE, Burns DM, Gaibler R, Mulhern TJ, Wong CA, Alladina J, Coppeta JR, Liu P, Wang JP, Azizgolshani H, Fezzie RF, Balestrini JL, Isenberg BC, Medoff BD, Finberg RW, Borenstein JT
High-throughput human primary cell-based airway model for evaluating influenza, coronavirus, or other respiratory viruses in vitro. Sci Rep. 2021 07 22; 11(1):14961.
High-throughput human primary cell-based airway model for evaluating influenza, coronavirus, or other respiratory viruses in vitro.
Santos J, Vedula EM, Lai W, Isenberg BC, Lewis DJ, Lang D, Sutherland D, Roberts TR, Harea GT, Wells C, Teece B, Karandikar P, Urban J, Risoleo T, Gimbel A, Solt D, Leazer S, Chung KK, Sukavaneshvar S, Batchinsky AI, Borenstein JT
Toward Development of a Higher Flow Rate Hemocompatible Biomimetic Microfluidic Blood Oxygenator. Micromachines (Basel). 2021 Jul 28; 12(8).
Toward Development of a Higher Flow Rate Hemocompatible Biomimetic Microfluidic Blood Oxygenator.
Santos JA, Gimbel AA, Peppas A, Truslow JG, Lang DA, Sukavaneshvar S, Solt D, Mulhern TJ, Markoski A, Kim ES, Hsiao JC, Lewis DJ, Harjes DI, DiBiasio C, Charest JL, Borenstein JT
Design and construction of three-dimensional physiologically-based vascular branching networks for respiratory assist devices. Lab Chip. 2021 11 25; 21(23):4637-4651.
Design and construction of three-dimensional physiologically-based vascular branching networks for respiratory assist devices.
3D Printed Monolithic Device for the Microfluidic Capture, Perfusion, and Analysis of Multicellular Spheroids. Front Med Technol. 2021; 3:646441.
3D Printed Monolithic Device for the Microfluidic Capture, Perfusion, and Analysis of Multicellular Spheroids.
The microfluidic artificial lung: Mimicking nature's blood path design to solve the biocompatibility paradox. Artif Organs. 2022 Jul; 46(7):1227-1239.
The microfluidic artificial lung: Mimicking nature's blood path design to solve the biocompatibility paradox.
Schueler J, Borenstein J, Buti L, Dong M, Masmoudi F, Hribar K, Anderson E, Sommergruber W
How to build a tumor: An industry perspective. Drug Discov Today. 2022 10; 27(10):103329.
How to build a tumor: An industry perspective.
Vedula EM, Isenberg BC, Santos J, Lai W, Lewis DJ, Sutherland D, Roberts TR, Harea GT, Wells C, Teece B, Urban J, Risoleo T, Solt D, Leazer S, Chung K, Sukavaneshvar S, Batchinsky AI, Borenstein JT
ASAIO journal (American Society for Artificial Internal Organs : 1992)
Multilayer Scaling of a Biomimetic Microfluidic Oxygenator. ASAIO J. 2022 10 01; 68(10):1312-1319.
Multilayer Scaling of a Biomimetic Microfluidic Oxygenator.
Gard AL, Luu RJ, Maloney R, Cooper MH, Cain BP, Azizgolshani H, Isenberg BC, Borenstein JT, Ong J, Charest JL, Vedula EM
A high-throughput, 28-day, microfluidic model of gingival tissue inflammation and recovery. Commun Biol. 2023 01 23; 6(1):92.
A high-throughput, 28-day, microfluidic model of gingival tissue inflammation and recovery.
Setty AA, Chiang TY, Santos JA, Isenberg BC, Vedula EM, Keating RA, Sutherland DW, Borenstein JT
Toward microfluidic integration of respiratory and renal organ support in a single cartridge. Artif Organs. 2023 Sep; 47(9):1442-1451.
Toward microfluidic integration of respiratory and renal organ support in a single cartridge.
Methods in molecular biology (Clifton, N.J.)
Dynamic Tumor Perfusion and Real-Time Monitoring in a Multiplexed 3D Printed Microdevice. Methods Mol Biol. 2023; 2679:287-304.
Dynamic Tumor Perfusion and Real-Time Monitoring in a Multiplexed 3D Printed Microdevice.
Isenberg BC, Vedula EM, Santos J, Lewis DJ, Roberts TR, Harea G, Sutherland D, Landis B, Blumenstiel S, Urban J, Lang D, Teece B, Lai W, Keating R, Chiang D, Batchinsky AI, Borenstein JT
Advanced science (Weinheim, Baden-Wurttemberg, Germany)
A Clinical-Scale Microfluidic Respiratory Assist Device with 3D Branching Vascular Networks. Adv Sci (Weinh). 2023 06; 10(18):e2207455.
A Clinical-Scale Microfluidic Respiratory Assist Device with 3D Branching Vascular Networks.
Jordan R, Ford-Scheimer SL, Alarcon RM, Atala A, Borenstein JT, Brimacombe KR, Cherry S, Clevers H, Davis MI, Funnell SGP, Gehrke L, Griffith LG, Grossman AC, Hartung T, Ingber DE, Kleinstreuer NC, Kuo CJ, Lee EM, Mummery CL, Pickett TE, Ramani S, Rosado-Olivieri EA, Struble EB, Wan Z, Williams MS, Hall MD, Ferrer M, Markossian S
Report of the Assay Guidance Workshop on 3-Dimensional Tissue Models for Antiviral Drug Development. J Infect Dis. 2023 10 03; 228(Suppl 5):S337-S354.
Report of the Assay Guidance Workshop on 3-Dimensional Tissue Models for Antiviral Drug Development.
Bell DC, Greg Lin HY, Akey A, Kraemer S, Borenstein JT, Dvorin JD, Chang A
Microscopy and microanalysis : the official journal of Microscopy Society of America, Microbeam Analysis Society, Microscopical Society of Canada
From Archeology to the Malaria Parasite, the Exciting Quests of Microscopy. Microsc Microanal. 2023 07 22; 29(Suppl 1):86-87.
From Archeology to the Malaria Parasite, the Exciting Quests of Microscopy.
Borenstein JT, Cummins G, Dutta A, Hamad E, Hughes MP, Jiang X, Lee HH, Lei KF, Tang XS, Zheng Y, Chen J
Bionanotechnology and bioMEMS (BNM): state-of-the-art applications, opportunities, and challenges. Lab Chip. 2023 11 21; 23(23):4928-4949.
Bionanotechnology and bioMEMS (BNM): state-of-the-art applications, opportunities, and challenges.
Fisher CR, Mba Medie F, Luu RJ, Gaibler RB, Mulhern TJ, Miller CR, Zhang CJ, Rubio LD, Marr EE, Vijayakumar V, Gabriel EP, Lopez Quezada L, Zhang CH, Anderson KS, Jorgensen WL, Alladina JW, Medoff BD, Borenstein JT, Gard AL
A High-Throughput, High-Containment Human Primary Epithelial Airway Organ-on-Chip Platform for SARS-CoV-2 Therapeutic Screening. Cells. 2023 11 16; 12(22).
A High-Throughput, High-Containment Human Primary Epithelial Airway Organ-on-Chip Platform for SARS-CoV-2 Therapeutic Screening.
Roberts TR, Persello A, Harea GT, Vedula EM, Isenberg BC, Zang Y, Santos J, Borenstein JT, Batchinsky AI
First 24-Hour-Long Intensive Care Unit Testing of a Clinical-Scale Microfluidic Oxygenator in Swine: A Safety and Feasibility Study. ASAIO J. 2024 06 01; 70(6):535-544.
First 24-Hour-Long Intensive Care Unit Testing of a Clinical-Scale Microfluidic Oxygenator in Swine: A Safety and Feasibility Study.
Lopez Quezada L, Mba Medie F, Luu RJ, Gaibler RB, Gabriel EP, Rubio LD, Mulhern TJ, Marr EE, Borenstein JT, Fisher CR, Gard AL
Predicting Clinical Outcomes of SARS-CoV-2 Drug Efficacy with a High-Throughput Human Airway Microphysiological System. Adv Biol (Weinh). 2024 11; 8(11):e2300511.
Predicting Clinical Outcomes of SARS-CoV-2 Drug Efficacy with a High-Throughput Human Airway Microphysiological System.
Manufacturable Biomimetic Microfluidic Oxygenator for Safer, Simpler Treatment of Respiratory Failure
Zhang Z, Borenstein J, Guiney L, Miller R, Sukavaneshvar S, Loose C
Polybetaine modification of PDMS microfluidic devices to resist thrombus formation in whole blood. Lab Chip. 2013 May 21; 13(10):1963-8.
Polybetaine modification of PDMS microfluidic devices to resist thrombus formation in whole blood.
Frohlich EM, Alonso JL, Borenstein JT, Zhang X, Arnaout MA, Charest JL
Topographically-patterned porous membranes in a microfluidic device as an in vitro model of renal reabsorptive barriers. Lab Chip. 2013 Jun 21; 13(12):2311-9.
Topographically-patterned porous membranes in a microfluidic device as an in vitro model of renal reabsorptive barriers.
Wang J, Boutin KG, Abdulhadi O, Personnat LD, Shazly T, Langer R, Channick CL, Borenstein JT
Fully biodegradable airway stents using amino alcohol-based poly(ester amide) elastomers. Adv Healthc Mater. 2013 Oct; 2(10):1329-36.
Fully biodegradable airway stents using amino alcohol-based poly(ester amide) elastomers.
Dungan J, Mathews J, Borenstein JT, Levin M, Koomson V
Electrical Impedance Correlated to Flow Rate in Elastomeric Valves: An Analog Material Memory. ACS Appl Mater Interfaces. 2025 Apr 09; 17(14):22107-22117.
Electrical Impedance Correlated to Flow Rate in Elastomeric Valves: An Analog Material Memory.
Cohen SJ, Chan RV, Keegan M, Andreoli CM, Borenstein JT, Miller JW, Gragoudas ES
Evaluation of tissue interactions with mechanical elements of a transscleral drug delivery device. Pharmaceutics. 2012 Mar 12; 4(1):212-29.
Evaluation of tissue interactions with mechanical elements of a transscleral drug delivery device.
Kim ES, Gustenhoven E, Mescher MJ, Pararas EE, Smith KA, Spencer AJ, Tandon V, Borenstein JT, Fiering J
A microfluidic reciprocating intracochlear drug delivery system with reservoir and active dose control. Lab Chip. 2014 Feb 21; 14(4):710-21.
A microfluidic reciprocating intracochlear drug delivery system with reservoir and active dose control.
Pereira MJ, Sundback CA, Lang N, Cho WK, Pomerantseva I, Ouyang B, Tao SL, McHugh K, Mwizerwa O, Vemula PK, Mochel MC, Carter DJ, Borenstein JT, Langer R, Ferreira LS, Karp JM, Masiakos PT
Combined surface micropatterning and reactive chemistry maximizes tissue adhesion with minimal inflammation. Adv Healthc Mater. 2014 Apr; 3(4):565-71.
Combined surface micropatterning and reactive chemistry maximizes tissue adhesion with minimal inflammation.
Epshteyn AA, Maher S, Taylor AJ, Holton AB, Borenstein JT, Cuiffi JD
Membrane-integrated microfluidic device for high-resolution live cell imaging. Biomicrofluidics. 2011 Dec; 5(4):46501-465016.
Membrane-integrated microfluidic device for high-resolution live cell imaging.
Wheeler SE, Borenstein JT, Clark AM, Ebrahimkhani MR, Fox IJ, Griffith L, Inman W, Lauffenburger D, Nguyen T, Pillai VC, Prantil-Baun R, Stolz DB, Taylor D, Ulrich T, Venkataramanan R, Wells A, Young C
All-human microphysical model of metastasis therapy. Stem Cell Res Ther. 2013; 4 Suppl 1:S11.
All-human microphysical model of metastasis therapy.
Lee DR, Chenoweth M, Chuong LH, Villaflores CW, Cuevas M, Vangala S, Borenstein J, Kwak H, Chima-Melton C, Han M, Skootsky SA, Chan Tack T, Branagan L, Martin H, Gupta R, Phan L, Sanchez MA, Malaak MM, Dermenchyan A, Pearson KN, Altunyan M, Barakat PF, Pablo R, Sarkisian C
A Multisite Electronic Health Record Integrated Remote Monitoring Intervention for Hypertension Improvement: Protocol for a Randomized Pragmatic Comparative Effectiveness Trial. JMIR Res Protoc. 2023 Oct 30; 12:e45915.
A Multisite Electronic Health Record Integrated Remote Monitoring Intervention for Hypertension Improvement: Protocol for a Randomized Pragmatic Comparative Effectiveness Trial.
Jeste DV, Peschin S, Buckwalter K, Blazer DG, McGuire MH, Moutier C, Doederlein A, Niederehe G, Altman B, Borenstein J, Saks E, Norquist G, Koob GF, Compton WM, Sperling A, Bain L, Glorioso D, Paul IH, Reynolds CF
The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry
Promoting Wellness in Older Adults with Mental Illnesses and Substance Use Disorders: Call to Action to All Stakeholders. Am J Geriatr Psychiatry. 2018 06; 26(6):617-630.
Promoting Wellness in Older Adults with Mental Illnesses and Substance Use Disorders: Call to Action to All Stakeholders.
Ebrahimkhani MR, Young CL, Lauffenburger DA, Griffith LG, Borenstein JT
Approaches to in vitro tissue regeneration with application for human disease modeling and drug development. Drug Discov Today. 2014 Jun; 19(6):754-62.
Approaches to in vitro tissue regeneration with application for human disease modeling and drug development.
Clark AM, Wheeler SE, Taylor DP, Pillai VC, Young CL, Prantil-Baun R, Nguyen T, Stolz DB, Borenstein JT, Lauffenburger DA, Venkataramanan R, Griffith LG, Wells A
Experimental biology and medicine (Maywood, N.J.)
A microphysiological system model of therapy for liver micrometastases. Exp Biol Med (Maywood). 2014 Sep; 239(9):1170-9.
A microphysiological system model of therapy for liver micrometastases.
Borenstein J, Yu HT, Wade S, Chiou CF, Rapkin A
Effect of an oral contraceptive containing ethinyl estradiol and drospirenone on premenstrual symptomatology and health-related quality of life. J Reprod Med. 2003 Feb; 48(2):79-85.
Effect of an oral contraceptive containing ethinyl estradiol and drospirenone on premenstrual symptomatology and health-related quality of life.
Lever AR, Park H, Mulhern TJ, Jackson GR, Comolli JC, Borenstein JT, Hayden PJ, Prantil-Baun R
Comprehensive evaluation of poly(I:C) induced inflammatory response in an airway epithelial model. Physiol Rep. 2015 Apr; 3(4).
Comprehensive evaluation of poly(I:C) induced inflammatory response in an airway epithelial model.
Tandon V, Kang WS, Spencer AJ, Kim ES, Pararas EE, McKenna MJ, Kujawa SG, Mescher MJ, Fiering J, Sewell WF, Borenstein JT
Microfabricated infuse-withdraw micropump component for an integrated inner-ear drug-delivery platform. Biomed Microdevices. 2015 Apr; 17(2):37.
Microfabricated infuse-withdraw micropump component for an integrated inner-ear drug-delivery platform.
The role of intracochlear drug delivery devices in the management of inner ear disease. Expert Opin Drug Deliv. 2015 Mar; 12(3):465-79.
The role of intracochlear drug delivery devices in the management of inner ear disease.
Rivera-Burgos D, Sarkar U, Lever AR, Avram MJ, Coppeta JR, Wishnok JS, Borenstein JT, Tannenbaum SR
Glucocorticoid Clearance and Metabolite Profiling in an In Vitro Human Airway Epithelium Lung Model. Drug Metab Dispos. 2016 Feb; 44(2):220-6.
Glucocorticoid Clearance and Metabolite Profiling in an In Vitro Human Airway Epithelium Lung Model.
Tandon V, Kang WS, Robbins TA, Spencer AJ, Kim ES, McKenna MJ, Kujawa SG, Fiering J, Pararas EE, Mescher MJ, Sewell WF, Borenstein JT
Microfabricated reciprocating micropump for intracochlear drug delivery with integrated drug/fluid storage and electronically controlled dosing. Lab Chip. 2016 Mar 07; 16(5):829-46.
Microfabricated reciprocating micropump for intracochlear drug delivery with integrated drug/fluid storage and electronically controlled dosing.
Organs-on-Chips: How Microsystems Technology Can Transform the Drug Development Process. IEEE Pulse. 2016 Mar-Apr; 7(2):22-6.
Organs-on-Chips: How Microsystems Technology Can Transform the Drug Development Process.
Gimbel AA, Flores E, Koo A, García-Cardeña G, Borenstein JT
Development of a biomimetic microfluidic oxygen transfer device. Lab Chip. 2016 08 16; 16(17):3227-34.
Development of a biomimetic microfluidic oxygen transfer device.
Micromechanical Device for Intracochlear Drug Delivery
A High-Throughput Flow System to Probe Biomechanics of Pathophysiology
Biomimetic Design and Construction of an Artificial Lung
Mescher MJ, Swan EE, Fiering J, Holmboe ME, Sewell WF, Kujawa SG, McKenna MJ, Borenstein JT
Journal of microelectromechanical systems : a joint IEEE and ASME publication on microstructures, microactuators, microsensors, and microsystems
Fabrication Methods and Performance of Low-Permeability Microfluidic Components for a Miniaturized Wearable Drug Delivery System. J Microelectromech Syst. 2009 Jun 01; 18(3):501-510.
Fabrication Methods and Performance of Low-Permeability Microfluidic Components for a Miniaturized Wearable Drug Delivery System.
Bettinger CJ, Cyr KM, Matsumoto A, Langer R, Borenstein JT, Kaplan DL
Advanced materials (Deerfield Beach, Fla.)
Silk Fibroin Microfluidic Devices. Adv Mater. 2007; 19(5):2847-2850.
Bettinger CJ, Weinberg EJ, Kulig KM, Vacanti JP, Wang Y, Borenstein JT, Langer R
Three-Dimensional Microfluidic Tissue-Engineering Scaffolds Using a Flexible Biodegradable Polymer. Adv Mater. 2005 Dec 08; 18(2):165-169.
Three-Dimensional Microfluidic Tissue-Engineering Scaffolds Using a Flexible Biodegradable Polymer.
Bettinger CJ, Zhang Z, Gerecht S, Borenstein JT, Langer R
Enhancement of In Vitro Capillary Tube Formation by Substrate Nanotopography. Adv Mater. 2008; 20(1):99-103.
Enhancement of In Vitro Capillary Tube Formation by Substrate Nanotopography.
Hoganson DM, Finkelstein EB, Owens GE, Hsiao JC, Eng KY, Kulig KM, Kim ES, Kniazeva T, Pomerantseva I, Neville CM, Turk JR, Fermini B, Borenstein JT, Vacanti JP
A bilayer small diameter in vitro vascular model for evaluation of drug induced vascular injury. Biomicrofluidics. 2016 Sep; 10(5):054116.
A bilayer small diameter in vitro vascular model for evaluation of drug induced vascular injury.
Coppeta JR, Mescher MJ, Isenberg BC, Spencer AJ, Kim ES, Lever AR, Mulhern TJ, Prantil-Baun R, Comolli JC, Borenstein JT
A portable and reconfigurable multi-organ platform for drug development with onboard microfluidic flow control. Lab Chip. 2016 12 20; 17(1):134-144.
A portable and reconfigurable multi-organ platform for drug development with onboard microfluidic flow control.
Kaihara S, Borenstein J, Koka R, Lalan S, Ochoa ER, Ravens M, Pien H, Cunningham B, Vacanti JP
Silicon micromachining to tissue engineer branched vascular channels for liver fabrication. Tissue Eng. 2000 Apr; 6(2):105-17.
Silicon micromachining to tissue engineer branched vascular channels for liver fabrication.
Yesilyurt V, Ayoob AM, Appel EA, Borenstein JT, Langer R, Anderson DG
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