Zhou Z, Tenen DG, Dvorak AM, Ackerman SJ
The gene for human eosinophil Charcot-Leyden crystal protein directs expression of lysophospholipase activity and spontaneous crystallization in transiently transfected COS cells. J Leukoc Biol. 1992 Dec; 52(6):588-95.
The gene for human eosinophil Charcot-Leyden crystal protein directs expression of lysophospholipase activity and spontaneous crystallization in transiently transfected COS cells.
Ultrastructural cytochemical, immunocytochemical and in situ hybridization methods with polyuridine probes detect mRNA in human mast cell granules. Histochem J. 2000 Jul; 32(7):423-38.
Ultrastructural cytochemical, immunocytochemical and in situ hybridization methods with polyuridine probes detect mRNA in human mast cell granules.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society
The vesiculo-vacuolar organelle (VVO). A new endothelial cell permeability organelle. J Histochem Cytochem. 2001 Apr; 49(4):419-32.
The vesiculo-vacuolar organelle (VVO). A new endothelial cell permeability organelle.
Dvorak AM, Morgan ES, Lichtenstein LM, Schleimer R
International archives of allergy and immunology
Ultrastructural autoradiographic analysis of RNA in isolated human lung mast cells during secretion and recovery from secretion. Int Arch Allergy Immunol. 2000 Jun; 122(2):124-36.
Ultrastructural autoradiographic analysis of RNA in isolated human lung mast cells during secretion and recovery from secretion.
Dvorak AM, Dickersin GR, Connell A, Carey RW, Dvorak HF
Degranulation mechanisms in human leukemic basophils. Clin Immunol Immunopathol. 1976 Mar; 5(2):235-46.
Degranulation mechanisms in human leukemic basophils.
Johnson PC, Ware JA, Cliveden PB, Smith M, Dvorak AM, Salzman EW
Measurement of ionized calcium in blood platelets with the photoprotein aequorin. Comparison with Quin 2. J Biol Chem. 1985 Feb 25; 260(4):2069-76.
Measurement of ionized calcium in blood platelets with the photoprotein aequorin. Comparison with Quin 2.
Proceedings: Morphologic studies in cellular hypersensitivity in guinea pigs and man. Monogr Allergy. 1974; 8(0):54-65.
Proceedings: Morphologic studies in cellular hypersensitivity in guinea pigs and man.
Dvorak AM, Connell AB, Proppe K, Dvorak HF
Journal of immunology (Baltimore, Md. : 1950)
Immunologic rejection of mammary adenocarcinoma (TA3-St) in C57BL/6 mice: participation of neutrophils and activated macrophages with fibrin formation. J Immunol. 1978 Apr; 120(4):1240-8.
Immunologic rejection of mammary adenocarcinoma (TA3-St) in C57BL/6 mice: participation of neutrophils and activated macrophages with fibrin formation.
Archives of pathology & laboratory medicine
Metastatic adenocarcinoma of unknown primary site: diagnostic electron microscopy to determine the site of tumor origin. Arch Pathol Lab Med. 1982 Jan; 106(1):21-4.
Metastatic adenocarcinoma of unknown primary site: diagnostic electron microscopy to determine the site of tumor origin.
Dvorak AM, Galli SJ, Schulman ES, Lichtenstein LM, Dvorak HF
Basophil and mast cell degranulation: ultrastructural analysis of mechanisms of mediator release. Fed Proc. 1983 May 15; 42(8):2510-5.
Basophil and mast cell degranulation: ultrastructural analysis of mechanisms of mediator release.
Electronmicroscopy of plasma cells in Crohn's disease. Lancet. 1979 Apr 14; 1(8120):834.
Electronmicroscopy of plasma cells in Crohn's disease.
Chatterjea D, Burns-Guydish SM, Sciuto TE, Dvorak A, Contag CH, Galli SJ
Adoptive transfer of mast cells does not enhance the impaired survival of Kit(W)/Kit(W-v) mice in a model of low dose intraperitoneal infection with bioluminescent Salmonella typhimurium. Immunol Lett. 2005 Jun 15; 99(1):122-9.
Adoptive transfer of mast cells does not enhance the impaired survival of Kit(W)/Kit(W-v) mice in a model of low dose intraperitoneal infection with bioluminescent Salmonella typhimurium.
Degranulation and recovery from degranulation of basophils and mast cells. Chem Immunol Allergy. 2005; 85:205-51.
Degranulation and recovery from degranulation of basophils and mast cells.
Mast cell secretory granules and lipid bodies contain the necessary machinery important for the in situ synthesis of proteins. Chem Immunol Allergy. 2005; 85:252-315.
Mast cell secretory granules and lipid bodies contain the necessary machinery important for the in situ synthesis of proteins.
Why are tumour blood vessels abnormal and why is it important to know? Br J Cancer. 2009 Mar 24; 100(6):865-9.
Why are tumour blood vessels abnormal and why is it important to know?
Murine mast cells (not neutrophils) are implicated in the biology of laminin. Blood. 1991 Apr 15; 77(8):1851-3.
Murine mast cells (not neutrophils) are implicated in the biology of laminin.
Dvorak AM, Schleimer RP, Lichtenstein LM
Human mast cells synthesize new granules during recovery from degranulation. In vitro studies with mast cells purified from human lungs. Blood. 1988 Jan; 71(1):76-85.
Human mast cells synthesize new granules during recovery from degranulation. In vitro studies with mast cells purified from human lungs.
Ultrastructural evidence for release of major basic protein-containing crystalline cores of eosinophil granules in vivo: cytotoxic potential in Crohn's disease. J Immunol. 1980 Jul; 125(1):460-2.
Ultrastructural evidence for release of major basic protein-containing crystalline cores of eosinophil granules in vivo: cytotoxic potential in Crohn's disease.
Tyler JD, Galli SJ, Snider ME, Dvorak AM, Steinmuller D
Cloned LYT-2+ cytolytic T lymphocytes destroy allogeneic tissue in vivo. J Exp Med. 1984 Jan 01; 159(1):234-43.
Cloned LYT-2+ cytolytic T lymphocytes destroy allogeneic tissue in vivo.
The electron microscopic appearance of Nocardia asteroides in human lung tissue. Arch Pathol Lab Med. 1984 Nov; 108(11):862-4.
The electron microscopic appearance of Nocardia asteroides in human lung tissue.
Ultrastructural analysis of human mast cells and basophils. Chem Immunol. 1995; 61:1-33.
Ultrastructural analysis of human mast cells and basophils.
Ishizaka T, Mitsui H, Yanagida M, Miura T, Dvorak AM
Development of human mast cells from their progenitors. Curr Opin Immunol. 1993 Dec; 5(6):937-43.
Development of human mast cells from their progenitors.
Dvorak AM, Morgan ES, Schleimer RP, Lichtenstein LM
Diamine oxidase-gold ultrastructural localization of histamine in isolated human lung mast cells stimulated to undergo anaphylactic degranulation and recovery in vitro. J Leukoc Biol. 1996 Jun; 59(6):824-34.
Diamine oxidase-gold ultrastructural localization of histamine in isolated human lung mast cells stimulated to undergo anaphylactic degranulation and recovery in vitro.
Feng D, Nagy JA, Hipp J, Pyne K, Dvorak HF, Dvorak AM
Reinterpretation of endothelial cell gaps induced by vasoactive mediators in guinea-pig, mouse and rat: many are transcellular pores. J Physiol. 1997 Nov 01; 504 ( Pt 3):747-61.
Reinterpretation of endothelial cell gaps induced by vasoactive mediators in guinea-pig, mouse and rat: many are transcellular pores.
Hammel I, Dvorak AM, Fox P, Shimoni E, Galli SJ
Defective cytoplasmic granule formation.II. Differences in patterns of radiolabeling of secretory granules in beige versus normal mouse pancreatic acinar cells after [3H]glycine administration in vivo. Cell Tissue Res. 1998 Sep; 293(3):445-52.
Defective cytoplasmic granule formation.II. Differences in patterns of radiolabeling of secretory granules in beige versus normal mouse pancreatic acinar cells after [3H]glycine administration in vivo.
Dvorak AM, Ackerman SJ, Furitsu T, Estrella P, Letourneau L, Ishizaka T
Mature eosinophils stimulated to develop in human-cord blood mononuclear cell cultures supplemented with recombinant human interleukin-5. II. Vesicular transport of specific granule matrix peroxidase, a mechanism for effecting piecemeal degranulation. Am J Pathol. 1992 Apr; 140(4):795-807.
Mature eosinophils stimulated to develop in human-cord blood mononuclear cell cultures supplemented with recombinant human interleukin-5. II. Vesicular transport of specific granule matrix peroxidase, a mechanism for effecting piecemeal degranulation.
Dvorak AM, Furitsu T, Estrella P, Letourneau L, Ishizaka T, Ackerman SJ
Ultrastructural localization of major basic protein in the human eosinophil lineage in vitro. J Histochem Cytochem. 1994 Nov; 42(11):1443-51.
Ultrastructural localization of major basic protein in the human eosinophil lineage in vitro.
Dvorak AM, Morgan ES, Lichtenstein LM, MacGlashan DW
Activated human basophils contain histamine in cytoplasmic vesicles. Int Arch Allergy Immunol. 1994 Sep; 105(1):8-11.
Activated human basophils contain histamine in cytoplasmic vesicles.
Ultrastructural immunolocalization of basic fibroblast growth factor to lipid bodies and secretory granules in human mast cells. Histochem J. 2001 Jul; 33(7):397-402.
Ultrastructural immunolocalization of basic fibroblast growth factor to lipid bodies and secretory granules in human mast cells.
McCarty JH, Monahan-Earley RA, Brown LF, Keller M, Gerhardt H, Rubin K, Shani M, Dvorak HF, Wolburg H, Bader BL, Dvorak AM, Hynes RO
Defective associations between blood vessels and brain parenchyma lead to cerebral hemorrhage in mice lacking alphav integrins. Mol Cell Biol. 2002 Nov; 22(21):7667-77.
Defective associations between blood vessels and brain parenchyma lead to cerebral hemorrhage in mice lacking alphav integrins.
Microwave fixation provides rapid, primary fixation for light and electron microscopy and for immunohistochemistry and immunocytochemistry. Eur J Morphol. 1991; 29(3):206-10.
Microwave fixation provides rapid, primary fixation for light and electron microscopy and for immunohistochemistry and immunocytochemistry.
Sun JF, Phung T, Shiojima I, Felske T, Upalakalin JN, Feng D, Kornaga T, Dor T, Dvorak AM, Walsh K, Benjamin LE
Proceedings of the National Academy of Sciences of the United States of America
Microvascular patterning is controlled by fine-tuning the Akt signal. Proc Natl Acad Sci U S A. 2005 Jan 04; 102(1):128-33.
Microvascular patterning is controlled by fine-tuning the Akt signal.
Legionnaires' disease. Arch Pathol Lab Med. 1980 Jun; 104(6):336-7.
Dvorak HF, Quay SC, Orenstein NS, Dvorak AM, Hahn P, Bitzer AM, Carvalho AC
Tumor shedding and coagulation. Science. 1981 May 22; 212(4497):923-4.
Mast cell abnormalities in the Chédiak-Higashi syndrome. Int Arch Allergy Immunol. 1993; 100(2):89-92.
Mast cell abnormalities in the Chédiak-Higashi syndrome.
McLeod RS, Antonioli D, Cullen J, Dvorak A, Onderdonk A, Silen W, Blair JE, Monahan-Earley R, Cisneros R, Cohen Z
Histologic and microbiologic features of biopsy samples from patients with normal and inflamed pouches. Dis Colon Rectum. 1994 Jan; 37(1):26-31.
Histologic and microbiologic features of biopsy samples from patients with normal and inflamed pouches.
Dvorak AM, Onderdonk AB, McLeod RS, Monahan-Earley RA, Antonioli DA, Cullen J, Blair JE, Cisneros R, Letourneau L, Morgan E
Ultrastructural identification of exocytosis of granules from human gut eosinophils in vivo. Int Arch Allergy Immunol. 1993; 102(1):33-45.
Ultrastructural identification of exocytosis of granules from human gut eosinophils in vivo.
Melo RC, Spencer LA, Perez SA, Neves JS, Bafford SP, Morgan ES, Dvorak AM, Weller PF
Laboratory investigation; a journal of technical methods and pathology
Vesicle-mediated secretion of human eosinophil granule-derived major basic protein. Lab Invest. 2009 Jul; 89(7):769-81.
Vesicle-mediated secretion of human eosinophil granule-derived major basic protein.
Teo GS, Ankrum JA, Martinelli R, Boetto SE, Simms K, Sciuto TE, Dvorak AM, Karp JM, Carman CV
Mesenchymal stem cells transmigrate between and directly through tumor necrosis factor-a-activated endothelial cells via both leukocyte-like and novel mechanisms. Stem Cells. 2012 Nov; 30(11):2472-86.
Mesenchymal stem cells transmigrate between and directly through tumor necrosis factor-a-activated endothelial cells via both leukocyte-like and novel mechanisms.
Gastrointestinal autonomic nerve (GAN) tumor. Ultrastructural evidence for a newly recognized entity. Arch Pathol Lab Med. 1986 Apr; 110(4):309-16.
Gastrointestinal autonomic nerve (GAN) tumor. Ultrastructural evidence for a newly recognized entity.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc
Correspondence re: N. Azumi, J. Joyce, and H. Battifora. Does rapid microwave fixation improve immunohistochemistry? Mod Pathol 3:368, 1990. Mod Pathol. 1991 Jan; 4(1):126-8.
Correspondence re: N. Azumi, J. Joyce, and H. Battifora. Does rapid microwave fixation improve immunohistochemistry? Mod Pathol 3:368, 1990.
Spencer LA, Melo RC, Perez SA, Bafford SP, Dvorak AM, Weller PF
Cytokine receptor-mediated trafficking of preformed IL-4 in eosinophils identifies an innate immune mechanism of cytokine secretion. Proc Natl Acad Sci U S A. 2006 Feb 28; 103(9):3333-8.
Cytokine receptor-mediated trafficking of preformed IL-4 in eosinophils identifies an innate immune mechanism of cytokine secretion.
Dvorak AM, McLeod RS, Onderdonk AB, Monahan-Earley RA, Cullen JB, Antonioli DA, Morgan E, Blair JE, Estrella P, Cisneros RL
Human gut mucosal mast cells: ultrastructural observations and anatomic variation in mast cell-nerve associations in vivo. Int Arch Allergy Immunol. 1992; 98(2):158-68.
Human gut mucosal mast cells: ultrastructural observations and anatomic variation in mast cell-nerve associations in vivo.
Advances in anatomy, embryology, and cell biology
Human mast cells. Adv Anat Embryol Cell Biol. 1989; 114:1-107.
Advances in experimental medicine and biology
Basophilic leukocytes in delayed-type hypersensitivity reactions in experimental animals and man. Adv Exp Med Biol. 1973; 29(0):573-9.
Basophilic leukocytes in delayed-type hypersensitivity reactions in experimental animals and man.
Basophils, mast cells, and cellular immunity in animals and man. Hum Pathol. 1972 Dec; 3(4):454-6.
Basophils, mast cells, and cellular immunity in animals and man.
Cytochemical localization of peroxidase activity in the developing erythrocyte. Am J Pathol. 1972 May; 67(2):303-26.
Cytochemical localization of peroxidase activity in the developing erythrocyte.
Dvorak AM, Galli SJ, Marcum JA, Nabel G, der Simonian H, Goldin J, Monahan RA, Pyne K, Cantor H, Rosenberg RD, Dvorak HF
Cloned mouse cells with natural killer function and cloned suppressor T cells express ultrastructural and biochemical features not shared by cloned inducer T cells. J Exp Med. 1983 Mar 01; 157(3):843-61.
Cloned mouse cells with natural killer function and cloned suppressor T cells express ultrastructural and biochemical features not shared by cloned inducer T cells.
Dvorak AM, Onderdonk AB, McLeod RS, Monahan-Earley RA, Cullen J, Antonioli DA, Blair JE, Morgan ES, Cisneros RL, Estrella P
Axonal necrosis of enteric autonomic nerves in continent ileal pouches. Possible implications for pathogenesis of Crohn's disease. Ann Surg. 1993 Mar; 217(3):260-71.
Axonal necrosis of enteric autonomic nerves in continent ileal pouches. Possible implications for pathogenesis of Crohn's disease.
Rodewald HR, Dessing M, Dvorak AM, Galli SJ
Identification of a committed precursor for the mast cell lineage. Science. 1996 Feb 09; 271(5250):818-22.
Identification of a committed precursor for the mast cell lineage.
Saito H, Hatake K, Dvorak AM, Leiferman KM, Donnenberg AD, Arai N, Ishizaka K, Ishizaka T
Selective differentiation and proliferation of hematopoietic cells induced by recombinant human interleukins. Proc Natl Acad Sci U S A. 1988 Apr; 85(7):2288-92.
Selective differentiation and proliferation of hematopoietic cells induced by recombinant human interleukins.
Feng D, Nagy JA, Pyne K, Dvorak HF, Dvorak AM
Ultrastructural localization of platelet endothelial cell adhesion molecule (PECAM-1, CD31) in vascular endothelium. J Histochem Cytochem. 2004 Jan; 52(1):87-101.
Ultrastructural localization of platelet endothelial cell adhesion molecule (PECAM-1, CD31) in vascular endothelium.
Melo RC, Perez SA, Spencer LA, Dvorak AM, Weller PF
Intragranular vesiculotubular compartments are involved in piecemeal degranulation by activated human eosinophils. Traffic. 2005 Oct; 6(10):866-79.
Intragranular vesiculotubular compartments are involved in piecemeal degranulation by activated human eosinophils.
Radke AL, Reynolds LE, Melo RC, Dvorak AM, Weller PF, Spencer LA
Mature human eosinophils express functional Notch ligands mediating eosinophil autocrine regulation. Blood. 2009 Mar 26; 113(13):3092-101.
Mature human eosinophils express functional Notch ligands mediating eosinophil autocrine regulation.
Journal of cellular and molecular medicine
Electron tomography and immunonanogold electron microscopy for investigating intracellular trafficking and secretion in human eosinophils. J Cell Mol Med. 2008 Aug; 12(4):1416-9.
Electron tomography and immunonanogold electron microscopy for investigating intracellular trafficking and secretion in human eosinophils.
Dvorak AM, Schleimer RP, Schulman ES, Lichtenstein LM
Human mast cells use conservation and condensation mechanisms during recovery from degranulation. In vitro studies with mast cells purified from human lungs. Lab Invest. 1986 Jun; 54(6):663-78.
Human mast cells use conservation and condensation mechanisms during recovery from degranulation. In vitro studies with mast cells purified from human lungs.
Lipid body-phagosome interaction in macrophages during infectious diseases: host defense or pathogen survival strategy? PLoS Pathog. 2012; 8(7):e1002729.
Lipid body-phagosome interaction in macrophages during infectious diseases: host defense or pathogen survival strategy?
Antonioli DA, Dayal Y, Dvorak AM, Banks PA
Zollinger-Ellison syndrome. Cure by surgical resection of a jejunal gastrinoma containing growth hormone releasing factor. Gastroenterology. 1987 Mar; 92(3):814-23.
Zollinger-Ellison syndrome. Cure by surgical resection of a jejunal gastrinoma containing growth hormone releasing factor.
Prete A, Lo AS, Sadow PM, Bhasin SS, Antonello ZA, Vodopivec DM, Ullas S, Sims JN, Clohessy J, Dvorak AM, Sciuto T, Bhasin M, Murphy-Ullrich JE, Lawler J, Karumanchi SA, Nucera C
Clinical cancer research : an official journal of the American Association for Cancer Research
Pericytes Elicit Resistance to Vemurafenib and Sorafenib Therapy in Thyroid Carcinoma via the TSP-1/TGFß1 Axis. Clin Cancer Res. 2018 12 01; 24(23):6078-6097.
Pericytes Elicit Resistance to Vemurafenib and Sorafenib Therapy in Thyroid Carcinoma via the TSP-1/TGFß1 Axis.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology
Vesicular transport of peroxidase in human eosinophilic myelocytes. Clin Exp Allergy. 1994 Jan; 24(1):10-8.
Vesicular transport of peroxidase in human eosinophilic myelocytes.
Beil WJ, Weller PF, Tzizik DM, Galli SJ, Dvorak AM
Ultrastructural immunogold localization of tumor necrosis factor-alpha to the matrix compartment of eosinophil secondary granules in patients with idiopathic hypereosinophilic syndrome. J Histochem Cytochem. 1993 Nov; 41(11):1611-5.
Ultrastructural immunogold localization of tumor necrosis factor-alpha to the matrix compartment of eosinophil secondary granules in patients with idiopathic hypereosinophilic syndrome.
Rapid microwave fixation of human tissues for light microscopic immunoperoxidase identification of diagnostically useful antigens. Lab Invest. 1987 Nov; 57(5):585-91.
Rapid microwave fixation of human tissues for light microscopic immunoperoxidase identification of diagnostically useful antigens.
Longworth DL, Monahan-Earley RA, Dvorak AM, Weller PF
Brugia malayi: arachidonic acid uptake into lipid bodies of adult parasites. Exp Parasitol. 1988 Apr; 65(2):251-7.
Brugia malayi: arachidonic acid uptake into lipid bodies of adult parasites.
International archives of allergy and applied immunology
Beige mouse mast cells generated in vitro: ultrastructural analysis of maturation induced by sodium butyrate and of IgE-mediated, antigen-dependent degranulation. Int Arch Allergy Appl Immunol. 1987; 82(3-4):261-8.
Beige mouse mast cells generated in vitro: ultrastructural analysis of maturation induced by sodium butyrate and of IgE-mediated, antigen-dependent degranulation.
Antigen-induced, IgE-mediated degranulation of cloned immature mast cells derived from normal mice. Am J Pathol. 1987 Mar; 126(3):535-45.
Antigen-induced, IgE-mediated degranulation of cloned immature mast cells derived from normal mice.
Electron microscopy of Paneth cells in Crohn's disease. Arch Pathol Lab Med. 1980 Jul; 104(7):393-4.
Electron microscopy of Paneth cells in Crohn's disease.
Galli SJ, Colvin RB, Verderber E, Galli AS, Monahan R, Dvorak AM, Dvorak HF
Preparation of a rabbit anti-guinea pig basophil serum: in vitro and in vivo characterization. J Immunol. 1978 Sep; 121(3):1157-66.
Preparation of a rabbit anti-guinea pig basophil serum: in vitro and in vivo characterization.
Dvorak AM, MacGlashan DW, Morgan ES, Lichtenstein LM
Histamine distribution in human basophil secretory granules undergoing FMLP-stimulated secretion and recovery. Blood. 1995 Nov 01; 86(9):3560-6.
Histamine distribution in human basophil secretory granules undergoing FMLP-stimulated secretion and recovery.
Dvorak AM, Kohn S, Morgan ES, Fox P, Nagy JA, Dvorak HF
The vesiculo-vacuolar organelle (VVO): a distinct endothelial cell structure that provides a transcellular pathway for macromolecular extravasation. J Leukoc Biol. 1996 Jan; 59(1):100-15.
The vesiculo-vacuolar organelle (VVO): a distinct endothelial cell structure that provides a transcellular pathway for macromolecular extravasation.
Dvorak AM, Ackerman SJ, Letourneau L, Morgan ES, Lichtenstein LM, MacGlashan DW
Vesicular transport of Charcot-Leyden crystal protein in tumor-promoting phorbol diester-stimulated human basophils. Lab Invest. 1996 May; 74(5):967-74.
Vesicular transport of Charcot-Leyden crystal protein in tumor-promoting phorbol diester-stimulated human basophils.
Dvorak AM, Letourneau L, Login GR, Weller PF, Ackerman SJ
Ultrastructural localization of the Charcot-Leyden crystal protein (lysophospholipase) to a distinct crystalloid-free granule population in mature human eosinophils. Blood. 1988 Jul; 72(1):150-8.
Ultrastructural localization of the Charcot-Leyden crystal protein (lysophospholipase) to a distinct crystalloid-free granule population in mature human eosinophils.
The American review of respiratory disease
Leaky vessels, fibrin deposition, and fibrosis: a sequence of events common to solid tumors and to many other types of disease. Am Rev Respir Dis. 1989 Oct; 140(4):1104-7.
Leaky vessels, fibrin deposition, and fibrosis: a sequence of events common to solid tumors and to many other types of disease.
Microscopy and microanalysis : the official journal of Microscopy Society of America, Microbeam Analysis Society, Microscopical Society of Canada
Contributions of electron microscopy to understand secretion of immune mediators by human eosinophils. Microsc Microanal. 2010 Dec; 16(6):653-60.
Contributions of electron microscopy to understand secretion of immune mediators by human eosinophils.
Thomas F, Motsinger-Reif AA, Hoskins JM, Dvorak A, Roy S, Alyasiri A, Myerson RJ, Fleshman JW, Tan BR, McLeod HL
Methylenetetrahydrofolate reductase genetic polymorphisms and toxicity to 5-FU-based chemoradiation in rectal cancer. Br J Cancer. 2011 Nov 22; 105(11):1654-62.
Methylenetetrahydrofolate reductase genetic polymorphisms and toxicity to 5-FU-based chemoradiation in rectal cancer.
Cold Spring Harbor perspectives in medicine
Vascular hyperpermeability, angiogenesis, and stroma generation. Cold Spring Harb Perspect Med. 2012 Feb; 2(2):a006544.
Vascular hyperpermeability, angiogenesis, and stroma generation.
Weitzman G, Galli SJ, Dvorak AM, Hammel I
Cloned mouse mast cells and normal mouse peritoneal mast cells. Determination of serotonin content and ability to synthesize serotonin in vitro. Int Arch Allergy Appl Immunol. 1985; 77(1-2):189-91.
Cloned mouse mast cells and normal mouse peritoneal mast cells. Determination of serotonin content and ability to synthesize serotonin in vitro.
Basophils and mast cells: morphologic insights into their biology, secretory patterns, and function. Prog Allergy. 1984; 34:1-141.
Basophils and mast cells: morphologic insights into their biology, secretory patterns, and function.
The Journal of investigative dermatology
Morphology of delayed-type hypersensitivity reactions in man. J Invest Dermatol. 1976 Sep; 67(3):391-401.
Morphology of delayed-type hypersensitivity reactions in man.
Dvorak AM, Weller PF, Harvey VS, Morgan ES, Dvorak HF
Ultrastructural localization of prostaglandin endoperoxide synthase (cyclooxygenase) to isolated, purified fractions of guinea pig peritoneal macrophage and line 10 hepatocarcinoma cell lipid bodies. Int Arch Allergy Immunol. 1993; 101(2):136-42.
Ultrastructural localization of prostaglandin endoperoxide synthase (cyclooxygenase) to isolated, purified fractions of guinea pig peritoneal macrophage and line 10 hepatocarcinoma cell lipid bodies.
Dvorak AM, Wiberg L, Monahan-Earley RA, Galli SJ
A simple technique to facilitate the ultrastructural analysis of cells in soft agar culture systems: demonstration of the development in vitro of morphologically mature mast cells and phagocytic macrophages from the bone marrow cells of genetically mast cell-deficient W/Wv or congenic normal mice. Lab Invest. 1990 Jun; 62(6):774-81.
A simple technique to facilitate the ultrastructural analysis of cells in soft agar culture systems: demonstration of the development in vitro of morphologically mature mast cells and phagocytic macrophages from the bone marrow cells of genetically mast cell-deficient W/Wv or congenic normal mice.
Ashida N, Senbanerjee S, Kodama S, Foo SY, Coggins M, Spencer JA, Zamiri P, Shen D, Li L, Sciuto T, Dvorak A, Gerszten RE, Lin CP, Karin M, Rosenzweig A
IKKß regulates essential functions of the vascular endothelium through kinase-dependent and -independent pathways. Nat Commun. 2011; 2:318.
IKKß regulates essential functions of the vascular endothelium through kinase-dependent and -independent pathways.
Dvorak AM, Hammond ME, Dvorak HF, Karnovsky MJ
Loss of cell surface material from peritoneal exudate cells associated with lymphocyte-mediated inhibition of macrophage migration from capillary tubes. Lab Invest. 1972 Dec; 27(6):561-74.
Loss of cell surface material from peritoneal exudate cells associated with lymphocyte-mediated inhibition of macrophage migration from capillary tubes.
Dvorak AM, Galli SJ, Morgan E, Galli AS, Hammond ME, Dvorak HF
Anaphylactic degranulation of guinea pig basophilic leukocytes. I. Fusion of granule membranes and cytoplasmic vesicles formation and resolution of degranulation sacs. Lab Invest. 1981 Feb; 44(2):174-91.
Anaphylactic degranulation of guinea pig basophilic leukocytes. I. Fusion of granule membranes and cytoplasmic vesicles formation and resolution of degranulation sacs.
Dvorak AM, Dvorak HF, Peters SP, Shulman ES, MacGlashan DW, Pyne K, Harvey VS, Galli SJ, Lichtenstein LM
Lipid bodies: cytoplasmic organelles important to arachidonate metabolism in macrophages and mast cells. J Immunol. 1983 Dec; 131(6):2965-76.
Lipid bodies: cytoplasmic organelles important to arachidonate metabolism in macrophages and mast cells.
Dvorak AM, Monahan RA, Osage JE, Dickersin GR
Mast-cell degranulation in Crohn's disease. Lancet. 1978 Mar 04; 1(8062):498.
Mast-cell degranulation in Crohn's disease.
Mouse mast cells and other granulated leukocyte clones. Ultrastructure of cloned mouse leukocytes. Monogr Allergy. 1983; 18:129-37.
Mouse mast cells and other granulated leukocyte clones. Ultrastructure of cloned mouse leukocytes.
Journal of the National Cancer Institute
Reaction of immune complexes with Hodgkin's disease tissue cultures. J Natl Cancer Inst. 1981 Jul; 67(1):3.
Reaction of immune complexes with Hodgkin's disease tissue cultures.
Diagnostic electron microscopy. I. Hematology: differential diagnosis of acute lymphoblastic and acute myeloblastic leukemia. Use of ultrastructural peroxidase cytochemistry and routine electron microscopic technology. Pathol Annu. 1981; 16 Pt 1:101-37.
Diagnostic electron microscopy. I. Hematology: differential diagnosis of acute lymphoblastic and acute myeloblastic leukemia. Use of ultrastructural peroxidase cytochemistry and routine electron microscopic technology.
Ultrastructural localization of nonspecific esterase activity in guinea pig and human monocytes, macrophages, and lymphocytes. Blood. 1981 Dec; 58(6):1089-99.
Ultrastructural localization of nonspecific esterase activity in guinea pig and human monocytes, macrophages, and lymphocytes.
Diamine oxidase-gold labels histamine in human mast-cell granules: a new enzyme-affinity ultrastructural method. J Histochem Cytochem. 1993 Jun; 41(6):787-800.
Diamine oxidase-gold labels histamine in human mast-cell granules: a new enzyme-affinity ultrastructural method.
Identification of the lineage of mature neutrophils and delineation of lipid body formation and apoptosis therein. Blood. 1996 May 01; 87(9):4013-5.
Identification of the lineage of mature neutrophils and delineation of lipid body formation and apoptosis therein.
Degranulation of basophilic leukocytes in allergic contact dermatitis reactions in man. J Immunol. 1976 Mar; 116(3):687-95.
Degranulation of basophilic leukocytes in allergic contact dermatitis reactions in man.
Ultrastructural studies of human basophils and mast cells. J Histochem Cytochem. 2005 Sep; 53(9):1043-70.
Ultrastructural studies of human basophils and mast cells.
Mast cell-derived mediators of enhanced microvascular permeability, vascular permeability factor/vascular endothelial growth factor, histamine, and serotonin, cause leakage of macromolecules through a new endothelial cell permeability organelle, the vesiculo-vacuolar organelle. Chem Immunol Allergy. 2005; 85:185-204.
Mast cell-derived mediators of enhanced microvascular permeability, vascular permeability factor/vascular endothelial growth factor, histamine, and serotonin, cause leakage of macromolecules through a new endothelial cell permeability organelle, the vesiculo-vacuolar organelle.
Costa JJ, Matossian K, Resnick MB, Beil WJ, Wong DT, Gordon JR, Dvorak AM, Weller PF, Galli SJ
Human eosinophils can express the cytokines tumor necrosis factor-alpha and macrophage inflammatory protein-1 alpha. J Clin Invest. 1993 Jun; 91(6):2673-84.
Human eosinophils can express the cytokines tumor necrosis factor-alpha and macrophage inflammatory protein-1 alpha.
Dvorak AM, Galli SJ, Galli AS, Hammond ME, Churchill WH, Dvorak HF
Tumor-basophil interactions in vitro--a scanning and transmission electron microscopic study. J Immunol. 1979 Jun; 122(6):2447-57.
Tumor-basophil interactions in vitro--a scanning and transmission electron microscopic study.
Dvorak AM, Monahan-Earley RA, Dvorak HF, Galli SJ
Ultrastructural cytochemical and autoradiographic demonstration of nonspecific esterase(s) in guinea pig basophils. J Histochem Cytochem. 1987 Mar; 35(3):351-60.
Ultrastructural cytochemical and autoradiographic demonstration of nonspecific esterase(s) in guinea pig basophils.
Dvorak AM, Schulman ES, Peters SP, MacGlashan DW, Newball HH, Schleimer RP, Lichtenstein LM
Immunoglobulin E-mediated degranulation of isolated human lung mast cells. Lab Invest. 1985 Jul; 53(1):45-56.
Immunoglobulin E-mediated degranulation of isolated human lung mast cells.
Immunoferritin electron microscopic studies with antibasophil serum of guinea pig basophil degranulation and regranulation in vitro. Clin Immunol Immunopathol. 1985 Oct; 37(1):63-76.
Immunoferritin electron microscopic studies with antibasophil serum of guinea pig basophil degranulation and regranulation in vitro.
Dvorak HF, Van DeWater L, Bitzer AM, Dvorak AM, Anderson D, Harvey VS, Bach R, Davis GL, DeWolf W, Carvalho AC
Procoagulant activity associated with plasma membrane vesicles shed by cultured tumor cells. Cancer Res. 1983 Sep; 43(9):4434-42.
Procoagulant activity associated with plasma membrane vesicles shed by cultured tumor cells.
New aspects of mast cell biology. Int Arch Allergy Immunol. 1997 Sep; 114(1):1-9.
Dickersin GR, Lott IT, Kolodny EH, Dvorak AM
A light and electron microscopic study of mannosidosis. Hum Pathol. 1980 May; 11(3):245-56.
A light and electron microscopic study of mannosidosis.
Galli SJ, Dvorak AM, Hammond ME, Morgan E, Galli AS, Dvorak HF
Guinea pig basophil morphology in vitro. I. Ultrastructure of uropod-bearing (motile) basophils and modulation of motile structures by serum and substrate effects. J Immunol. 1981 Mar; 126(3):1066-74.
Guinea pig basophil morphology in vitro. I. Ultrastructure of uropod-bearing (motile) basophils and modulation of motile structures by serum and substrate effects.
Schnitzer JE, McIntosh DP, Dvorak AM, Liu J, Oh P
Separation of caveolae from associated microdomains of GPI-anchored proteins. Science. 1995 Sep 08; 269(5229):1435-9.
Separation of caveolae from associated microdomains of GPI-anchored proteins.
Ultrastructural morphology of immature mast cells in sequential suspension cultures of human cord blood cells supplemented with c-kit ligand; distinction from mature basophilic leukocytes undergoing secretion in the same cultures. J Leukoc Biol. 1993 Nov; 54(5):465-85.
Ultrastructural morphology of immature mast cells in sequential suspension cultures of human cord blood cells supplemented with c-kit ligand; distinction from mature basophilic leukocytes undergoing secretion in the same cultures.
Schnitzer JE, Oh P, Jacobson BS, Dvorak AM
Caveolae from luminal plasmalemma of rat lung endothelium: microdomains enriched in caveolin, Ca(2+)-ATPase, and inositol trisphosphate receptor. Proc Natl Acad Sci U S A. 1995 Feb 28; 92(5):1759-63.
Caveolae from luminal plasmalemma of rat lung endothelium: microdomains enriched in caveolin, Ca(2+)-ATPase, and inositol trisphosphate receptor.
Dvorak AM, Klebanoff SJ, Henderson WR, Monahan RA, Pyne K, Galli SJ
Vesicular uptake of eosinophil peroxidase by guinea pig basophils and by cloned mouse mast cells and granule-containing lymphoid cells. Am J Pathol. 1985 Mar; 118(3):425-38.
Vesicular uptake of eosinophil peroxidase by guinea pig basophils and by cloned mouse mast cells and granule-containing lymphoid cells.
Neves JS, Perez SA, Spencer LA, Melo RC, Reynolds L, Ghiran I, Mahmudi-Azer S, Odemuyiwa SO, Dvorak AM, Moqbel R, Weller PF
Eosinophil granules function extracellularly as receptor-mediated secretory organelles. Proc Natl Acad Sci U S A. 2008 Nov 25; 105(47):18478-83.
Eosinophil granules function extracellularly as receptor-mediated secretory organelles.
Cellular and vascular manifestations of cell-mediated immunity. Hum Pathol. 1986 Feb; 17(2):122-37.
Cellular and vascular manifestations of cell-mediated immunity.
Dvorak AM, Dickersin GR, Osage JE, Monahan RA
Absence of virus structures in Crohn's disease tissues studied by electron microscopy. Lancet. 1978 Feb 11; 1(8059):328.
Absence of virus structures in Crohn's disease tissues studied by electron microscopy.
Dvorak HF, Mihm MC, Dvorak AM, Barnes BA, Galli SJ
The microvasculature is the critical target of the immune response in vascularized skin allograft rejection. J Invest Dermatol. 1980 May; 74(5):280-4.
The microvasculature is the critical target of the immune response in vascularized skin allograft rejection.
Crohn's disease: transmission electron microscopic studies. II. Immunologic inflammatory response. Alterations of mast cells, basophils, eosinophils, and the microvasculature. Hum Pathol. 1980 Nov; 11(6):606-19.
Crohn's disease: transmission electron microscopic studies. II. Immunologic inflammatory response. Alterations of mast cells, basophils, eosinophils, and the microvasculature.
Dvorak HF, Brown LF, Detmar M, Dvorak AM
Vascular permeability factor/vascular endothelial growth factor, microvascular hyperpermeability, and angiogenesis. Am J Pathol. 1995 May; 146(5):1029-39.
Vascular permeability factor/vascular endothelial growth factor, microvascular hyperpermeability, and angiogenesis.
Feng D, Nagy JA, Pyne K, Hammel I, Dvorak HF, Dvorak AM
Microcirculation (New York, N.Y. : 1994)
Pathways of macromolecular extravasation across microvascular endothelium in response to VPF/VEGF and other vasoactive mediators. Microcirculation. 1999 Mar; 6(1):23-44.
Pathways of macromolecular extravasation across microvascular endothelium in response to VPF/VEGF and other vasoactive mediators.
Ribonuclease-gold labels proteoglycan-containing cytoplasmic granules and ribonucleic acid-containing organelles--a survey. Histol Histopathol. 1999 04; 14(2):597-626.
Ribonuclease-gold labels proteoglycan-containing cytoplasmic granules and ribonucleic acid-containing organelles--a survey.
Ribonuclease-gold ultrastructural localization of heparin in isolated human lung mast cells stimulated to undergo anaphylactic degranulation and recovery in vitro. Clin Exp Allergy. 1999 Aug; 29(8):1118-28.
Ribonuclease-gold ultrastructural localization of heparin in isolated human lung mast cells stimulated to undergo anaphylactic degranulation and recovery in vitro.
Mast-cell degranulation in human hearts. N Engl J Med. 1986 Oct 09; 315(15):969-70.
Mast-cell degranulation in human hearts.
Galli SJ, Dvorak AM, Marcum JA, Nabel G, Goldin JM, Rosenberg RD, Cantor H, Dvorak HF
Mouse mast cell clones: modulation of functional maturity in vitro. Monogr Allergy. 1983; 18:166-70.
Mouse mast cell clones: modulation of functional maturity in vitro.
Dvorak AM, Lett-Brown MA, Thueson DO, Pyne K, Raghuprasad PK, Galli SJ, Grant JA
Histamine-releasing activity (HRA). III. HRA induces human basophil histamine release by provoking noncytotoxic granule exocytosis. Clin Immunol Immunopathol. 1984 Aug; 32(2):142-50.
Histamine-releasing activity (HRA). III. HRA induces human basophil histamine release by provoking noncytotoxic granule exocytosis.
Dvorak HF, Orenstein NS, Dvorak AM, Hammond ME, Roblin RO, Feder J, Schott CF, Goodwin J, Morgan E
Isolation of the cytoplasmic granules of guinea pig basophilic leukocytes: identification of esterase and protease activities. J Immunol. 1977 Jul; 119(1):38-46.
Isolation of the cytoplasmic granules of guinea pig basophilic leukocytes: identification of esterase and protease activities.
Crohn's disease: transmission electron microscopic studies. I. Barrier function. Possible changes related to alterations of cell coat, mucous coat, epithelial cells, and Paneth cells. Hum Pathol. 1980 Sep; 11(5 Suppl):561-71.
Crohn's disease: transmission electron microscopic studies. I. Barrier function. Possible changes related to alterations of cell coat, mucous coat, epithelial cells, and Paneth cells.
Nagy JA, Senger DR, Dvorak HF, Dvorak AM
Ultrastructural localization of vascular permeability factor/vascular endothelial growth factor (VPF/VEGF) to the abluminal plasma membrane and vesiculovacuolar organelles of tumor microvascular endothelium. J Histochem Cytochem. 1995 Apr; 43(4):381-9.
Ultrastructural localization of vascular permeability factor/vascular endothelial growth factor (VPF/VEGF) to the abluminal plasma membrane and vesiculovacuolar organelles of tumor microvascular endothelium.
Beil WJ, Weller PF, Peppercorn MA, Galli SJ, Dvorak AM
Ultrastructural immunogold localization of subcellular sites of TNF-alpha in colonic Crohn's disease. J Leukoc Biol. 1995 Sep; 58(3):284-98.
Ultrastructural immunogold localization of subcellular sites of TNF-alpha in colonic Crohn's disease.
Galli SJ, Galli AS, Dvorak AM, Dvorak HF
Metabolic studies of guinea pig basophilic leukocytes in short-term tissue culture. I. Measurement of histaminesynthesizing capacity by using an isotopic-thin layer chromatographic assay. J Immunol. 1976 Oct; 117(4):1085-92.
Metabolic studies of guinea pig basophilic leukocytes in short-term tissue culture. I. Measurement of histaminesynthesizing capacity by using an isotopic-thin layer chromatographic assay.
Senger DR, Van de Water L, Brown LF, Nagy JA, Yeo KT, Yeo TK, Berse B, Jackman RW, Dvorak AM, Dvorak HF
Vascular permeability factor (VPF, VEGF) in tumor biology. Cancer Metastasis Rev. 1993 Sep; 12(3-4):303-24.
Vascular permeability factor (VPF, VEGF) in tumor biology.
Kempf W, Kadin ME, Dvorak AM, Lord CC, Burg G, Letvin NL, Koralnik IJ
Endogenous retroviral elements, but not exogenous retroviruses, are detected in CD30-positive lymphoproliferative disorders of the skin. Carcinogenesis. 2003 Feb; 24(2):301-6.
Endogenous retroviral elements, but not exogenous retroviruses, are detected in CD30-positive lymphoproliferative disorders of the skin.
Satchi-Fainaro R, Mamluk R, Wang L, Short SM, Nagy JA, Feng D, Dvorak AM, Dvorak HF, Puder M, Mukhopadhyay D, Folkman J
Inhibition of vessel permeability by TNP-470 and its polymer conjugate, caplostatin. Cancer Cell. 2005 Mar; 7(3):251-61.
Inhibition of vessel permeability by TNP-470 and its polymer conjugate, caplostatin.
Dissecting aneurysm of the gastroduodenal artery: anatomic basis for the clinical syndrome of abdominal apoplexy. Ann Surg. 1969 Mar; 169(3):425-8.
Dissecting aneurysm of the gastroduodenal artery: anatomic basis for the clinical syndrome of abdominal apoplexy.
Dvorak AM, Hammond ME, Morgan E, Orenstein NS, Galli SJ, Dvorak HF
Evidence for a vesicular transport mechanism in guinea pig basophilic leukocytes. Lab Invest. 1980 Feb; 42(2):263-76.
Evidence for a vesicular transport mechanism in guinea pig basophilic leukocytes.
Nabel G, Galli SJ, Dvorak AM, Dvorak HF, Cantor H
Inducer T lymphocytes synthesize a factor that stimulates proliferation of cloned mast cells. Nature. 1981 May 28; 291(5813):332-4.
Inducer T lymphocytes synthesize a factor that stimulates proliferation of cloned mast cells.
Dvorak AM, Mihm MC, Osage JE, Kwan TH, Austen KF, Wintroub BU
Bullous pemphigoid, an ultrastructural study of the inflammatory response: eosinophil, basophil and mast cell granule changes in multiple biopsies from one patient. J Invest Dermatol. 1982 Feb; 78(2):91-101.
Bullous pemphigoid, an ultrastructural study of the inflammatory response: eosinophil, basophil and mast cell granule changes in multiple biopsies from one patient.
Dvorak AM, Tepper RI, Weller PF, Morgan ES, Estrella P, Monahan-Earley RA, Galli SJ
Piecemeal degranulation of mast cells in the inflammatory eyelid lesions of interleukin-4 transgenic mice. Evidence of mast cell histamine release in vivo by diamine oxidase-gold enzyme-affinity ultrastructural cytochemistry. Blood. 1994 Jun 15; 83(12):3600-12.
Piecemeal degranulation of mast cells in the inflammatory eyelid lesions of interleukin-4 transgenic mice. Evidence of mast cell histamine release in vivo by diamine oxidase-gold enzyme-affinity ultrastructural cytochemistry.
Dvorak AM, Estrella P, Mitsui H, Ishizaka T
C-kit ligand induction of immature neutrophils in cultures of human umbilical cord blood. Eur J Cell Biol. 1993 Dec; 62(2):422-31.
C-kit ligand induction of immature neutrophils in cultures of human umbilical cord blood.
Progress in histochemistry and cytochemistry
Methods of microwave fixation for microscopy. A review of research and clinical applications: 1970-1992. Prog Histochem Cytochem. 1994; 27(4):1-127.
Methods of microwave fixation for microscopy. A review of research and clinical applications: 1970-1992.
Giardia Lamblia. N Engl J Med. 1993 Apr 08; 328(14):1010.
Circulating membrane vesicles in leukemic blood. Cancer Res. 1985 Nov; 45(11 Pt 2):5944-51.
Circulating membrane vesicles in leukemic blood.
Vitamin A in Crohn's disease. Lancet. 1980 Jun 14; 1(8181):1303-4.
Dvorak AM, Osage JE, Monahan RA, Dickersin GR
Crohn's disease: transmission electron microscopic studies. III. Target tissues. Proliferation of and injury to smooth muscle and the autonomic nervous system. Hum Pathol. 1980 Nov; 11(6):620-34.
Crohn's disease: transmission electron microscopic studies. III. Target tissues. Proliferation of and injury to smooth muscle and the autonomic nervous system.
Fox CC, Dvorak AM, MacGlashan DW, Lichtenstein LM
Histamine-containing cells in human peritoneal fluid. J Immunol. 1984 May; 132(5):2177-9.
Histamine-containing cells in human peritoneal fluid.
Melanoma. An ultrastructural study of the host inflammatory and vascular responses. J Invest Dermatol. 1980 Nov; 75(5):388-93.
Melanoma. An ultrastructural study of the host inflammatory and vascular responses.
Dvorak AM, Morgan ES, Monahan-Earley RA, Estrella P, Schleimer RP, Weller PF, Tepper RI, Lichtenstein LM, Galli SJ
Analysis of mast cell activation using diamine oxidase-gold enzyme-affinity ultrastructural cytochemistry. Int Arch Allergy Immunol. 1995 May-Jun; 107(1-3):87-9.
Analysis of mast cell activation using diamine oxidase-gold enzyme-affinity ultrastructural cytochemistry.
VEGF-A and the induction of pathological angiogenesis. Annu Rev Pathol. 2007; 2:251-75.
VEGF-A and the induction of pathological angiogenesis.
Reynolds DS, Serafin WE, Faller DV, Wall DA, Abbas AK, Dvorak AM, Austen KF, Stevens RL
Immortalization of murine connective tissue-type mast cells at multiple stages of their differentiation by coculture of splenocytes with fibroblasts that produce Kirsten sarcoma virus. J Biol Chem. 1988 Sep 05; 263(25):12783-91.
Immortalization of murine connective tissue-type mast cells at multiple stages of their differentiation by coculture of splenocytes with fibroblasts that produce Kirsten sarcoma virus.
Ultrastructural localization of the Charcot-Leyden crystal protein (lysophospholipase) to granules and intragranular crystals in mature human basophils. Lab Invest. 1989 Apr; 60(4):557-67.
Ultrastructural localization of the Charcot-Leyden crystal protein (lysophospholipase) to granules and intragranular crystals in mature human basophils.
Dvorak HF, Mihm MC, Dvorak AM, Barnes BA, Manseau EJ, Galli SJ
Rejection of first-set skin allografts in man. the microvasculature is the critical target of the immune response. J Exp Med. 1979 Aug 01; 150(2):322-37.
Rejection of first-set skin allografts in man. the microvasculature is the critical target of the immune response.
Basophilic leucocytes: structure, function and role in disease. Clin Haematol. 1975 Oct; 4(3):651-83.
Basophilic leucocytes: structure, function and role in disease.
Defective cytoplasmic granule formation. I. Abnormalities affecting tissue mast cells and pancreatic acinar cells of beige mice. Lab Invest. 1987 Mar; 56(3):321-8.
Defective cytoplasmic granule formation. I. Abnormalities affecting tissue mast cells and pancreatic acinar cells of beige mice.
Surface membrane traffic in guinea pig basophils exposed to cationic ferritin. Int Arch Allergy Appl Immunol. 1985; 77(1-2):267-73.
Surface membrane traffic in guinea pig basophils exposed to cationic ferritin.
Ultrastructure of human basophils developing in vitro. Evidence for the acquisition of peroxidase by basophils and for different effects of human and murine growth factors on human basophil and eosinophil maturation. Lab Invest. 1985 Jul; 53(1):57-71.
Ultrastructure of human basophils developing in vitro. Evidence for the acquisition of peroxidase by basophils and for different effects of human and murine growth factors on human basophil and eosinophil maturation.
Galli SJ, Colvin RB, Orenstein NS, Dvorak AM, Dvorak HF
Patients without basophils. Lancet. 1977 Aug 20; 2(8034):409.
Ricci A, Monahan RA, Paradise C, Robinson S, Dvorak AM
Unusual inclusions in plasmacytoid cells. Their occurrence in a patient with Waldenström's macroglobulinemia. Arch Pathol Lab Med. 1982 Sep; 106(9):452-7.
Unusual inclusions in plasmacytoid cells. Their occurrence in a patient with Waldenström's macroglobulinemia.
Crohn's disease. Ultrastructural studies showing basophil leukocyte granule changes and lymphocyte parallel tubular arrays in peripheral blood. Arch Pathol Lab Med. 1982 Mar; 106(3):145-9.
Crohn's disease. Ultrastructural studies showing basophil leukocyte granule changes and lymphocyte parallel tubular arrays in peripheral blood.
A role for cytoplasmic vesicles in anaphylactic degranulation of guinea pig basophils. Int Arch Allergy Appl Immunol. 1981; 66 Suppl 1:234-8.
A role for cytoplasmic vesicles in anaphylactic degranulation of guinea pig basophils.
Human eosinophils in vitro. An ultrastructural morphology primer. Histol Histopathol. 1994 Apr; 9(2):339-74.
Human eosinophils in vitro. An ultrastructural morphology primer.
Dvorak HF, Nagy JA, Feng D, Brown LF, Dvorak AM
Current topics in microbiology and immunology
Vascular permeability factor/vascular endothelial growth factor and the significance of microvascular hyperpermeability in angiogenesis. Curr Top Microbiol Immunol. 1999; 237:97-132.
Vascular permeability factor/vascular endothelial growth factor and the significance of microvascular hyperpermeability in angiogenesis.
Images in clinical medicine. An apoptotic eosinophil. N Engl J Med. 1999 Feb 11; 340(6):437.
Images in clinical medicine. An apoptotic eosinophil.
Massey WA, Guo CB, Dvorak AM, Hubbard WC, Bhagavan BS, Cohan VL, Warner JA, Kagey-Sobotka A, Lichtenstein LM
Human uterine mast cells. Isolation, purification, characterization, ultrastructure, and pharmacology. J Immunol. 1991 Sep 01; 147(5):1621-7.
Human uterine mast cells. Isolation, purification, characterization, ultrastructure, and pharmacology.
Nagy JA, Vasile E, Feng D, Sundberg C, Brown LF, Manseau EJ, Dvorak AM, Dvorak HF
Cold Spring Harbor symposia on quantitative biology
VEGF-A induces angiogenesis, arteriogenesis, lymphangiogenesis, and vascular malformations. Cold Spring Harb Symp Quant Biol. 2002; 67:227-37.
VEGF-A induces angiogenesis, arteriogenesis, lymphangiogenesis, and vascular malformations.
Activated human eosinophils. Int Arch Allergy Immunol. 2005 Dec; 138(4):347-9.
Hammond ME, Dvorak AM, Roblin RO, Morgan ES, Dvorak HF
Journal of the Reticuloendothelial Society
Effect of E-amino caproic acid on macrohage cell coat and migration inhibtion. J Reticuloendothel Soc. 1978 Jul; 24(1):63-72.
Effect of E-amino caproic acid on macrohage cell coat and migration inhibtion.
Melo RC, D'Avila H, Wan HC, Bozza PT, Dvorak AM, Weller PF
Lipid bodies in inflammatory cells: structure, function, and current imaging techniques. J Histochem Cytochem. 2011 May; 59(5):540-56.
Lipid bodies in inflammatory cells: structure, function, and current imaging techniques.
Long JC, Dvorak AM, Quay SC, Stamatos C, Chi SY
Reaction of immune complexes with Hodgkin's disease tissue cultures: radioimmune assay and immunoferritin electron microscopy. J Natl Cancer Inst. 1979 Apr; 62(4):787-97.
Reaction of immune complexes with Hodgkin's disease tissue cultures: radioimmune assay and immunoferritin electron microscopy.
Longworth DL, Foster DW, Dvorak AM, Weller PF
Incorporation of arachidonic acid by microfilariae of Brugia malayi. J Infect Dis. 1985 Dec; 152(6):1317-23.
Incorporation of arachidonic acid by microfilariae of Brugia malayi.
Morphologic changes in primary neuroendocrine carcinoma of the skin following radiation therapy. Hum Pathol. 1986 Feb; 17(2):198-201.
Morphologic changes in primary neuroendocrine carcinoma of the skin following radiation therapy.
Ultrafast microwave energy fixation for electron microscopy. J Histochem Cytochem. 1986 Mar; 34(3):381-7.
Ultrafast microwave energy fixation for electron microscopy.
Differentiation between Crohn's disease and other inflammatory conditions by electron microscopy. Ann Surg. 1985 Jan; 201(1):53-63.
Differentiation between Crohn's disease and other inflammatory conditions by electron microscopy.
Immunologic rejection of diethylnitrosamine-induced hepatomas in strain 2 guinea pigs: participation of basophilic leukocytes and macrophage aggregates. J Exp Med. 1973 Mar 01; 137(3):751-75.
Immunologic rejection of diethylnitrosamine-induced hepatomas in strain 2 guinea pigs: participation of basophilic leukocytes and macrophage aggregates.
Galli SJ, Dvorak AM, Marcum JA, Ishizaka T, Nabel G, Der Simonian H, Pyne K, Goldin JM, Rosenberg RD, Cantor H, Dvorak HF
Mast cell clones: a model for the analysis of cellular maturation. J Cell Biol. 1982 Nov; 95(2 Pt 1):435-44.
Mast cell clones: a model for the analysis of cellular maturation.
What do mast cells have to do with delayed hypersensitivity? Lab Invest. 1984 Apr; 50(4):365-8.
What do mast cells have to do with delayed hypersensitivity?
Anaphylactic degranulation of guinea pig basophilic leukocytes. II. Evidence for regranulation of mature basophils during recovery from degranulation in vitro. Lab Invest. 1982 May; 46(5):461-75.
Anaphylactic degranulation of guinea pig basophilic leukocytes. II. Evidence for regranulation of mature basophils during recovery from degranulation in vitro.
Kistler JP, Lott IT, Kolodny EH, Friedman RB, Nersasian R, Schnur J, Mihm MC, Dvorak AM, Dickersin R
Mannosidosis. New clinical presentation, enzyme studied, and carbohydrate analysis. Arch Neurol. 1977 Jan; 34(1):45-51.
Mannosidosis. New clinical presentation, enzyme studied, and carbohydrate analysis.
Morphology of delayed-type hypersensitivity reactions in man. II. Ultrastructural alterations affecting the microvasculature and the tissue mast cells. Lab Invest. 1976 Feb; 34(2):179-91.
Morphology of delayed-type hypersensitivity reactions in man. II. Ultrastructural alterations affecting the microvasculature and the tissue mast cells.
Costa JJ, Demetri GD, Harrist TJ, Dvorak AM, Hayes DF, Merica EA, Menchaca DM, Gringeri AJ, Schwartz LB, Galli SJ
Recombinant human stem cell factor (kit ligand) promotes human mast cell and melanocyte hyperplasia and functional activation in vivo. J Exp Med. 1996 Jun 01; 183(6):2681-6.
Recombinant human stem cell factor (kit ligand) promotes human mast cell and melanocyte hyperplasia and functional activation in vivo.
Dvorak AM, Warner JA, Fox P, Lichtenstein LM, Macglashan DW
Recovery of human basophils after FMLP-stimulated secretion. Clin Exp Allergy. 1996 Mar; 26(3):281-94.
Recovery of human basophils after FMLP-stimulated secretion.
Mallinckrodt Professor of Pathology, Emeritus
Albert L. Sheffer Professor of Medicine in the Field of Allergic Disease
Mariana Concepcion Castells, M.D., Ph.D.
Prince Turki bin Abdul Aziz Al-Saud Professor of Pediatrics
William Bosworth Castle Professor of Medicine
Dvorak AM, Schleimer RP, Dvorak HE, Lichtenstein LM, Weller PF
Human Lung Mast Cell and Alveolar Macrophage Cytoplasmic Lipid Bodies Contain Arachidonic Acid and Prostaglandin Endoperoxide Synthase (Cyclooxygenase), the Substrate and Enzyme Necessary for Prostaglandin Production. Int Arch Allergy Immunol. 1992; 99(2-4):208-217.
Human Lung Mast Cell and Alveolar Macrophage Cytoplasmic Lipid Bodies Contain Arachidonic Acid and Prostaglandin Endoperoxide Synthase (Cyclooxygenase), the Substrate and Enzyme Necessary for Prostaglandin Production.
Journal of thrombosis and haemostasis : JTH
Evolutionary origins of the blood vascular system and endothelium. J Thromb Haemost. 2013 Jun; 11 Suppl 1:46-66.
Evolutionary origins of the blood vascular system and endothelium.
Kraft S, Jouvin MH, Kulkarni N, Kissing S, Morgan ES, Dvorak AM, Schröder B, Saftig P, Kinet JP
The tetraspanin CD63 is required for efficient IgE-mediated mast cell degranulation and anaphylaxis. J Immunol. 2013 Sep 15; 191(6):2871-8.
The tetraspanin CD63 is required for efficient IgE-mediated mast cell degranulation and anaphylaxis.
Dharaneeswaran H, Abid MR, Yuan L, Dupuis D, Beeler D, Spokes KC, Janes L, Sciuto T, Kang PM, Jaminet SS, Dvorak A, Grant MA, Regan ER, Aird WC
FOXO1-mediated activation of Akt plays a critical role in vascular homeostasis. Circ Res. 2014 Jul 07; 115(2):238-251.
FOXO1-mediated activation of Akt plays a critical role in vascular homeostasis.
Martinelli R, Zeiger AS, Whitfield M, Sciuto TE, Dvorak A, Van Vliet KJ, Greenwood J, Carman CV
Probing the biomechanical contribution of the endothelium to lymphocyte migration: diapedesis by the path of least resistance. J Cell Sci. 2014 Sep 01; 127(Pt 17):3720-34.
Probing the biomechanical contribution of the endothelium to lymphocyte migration: diapedesis by the path of least resistance.
Lin CI, Merley A, Sciuto TE, Li D, Dvorak AM, Melero-Martin JM, Dvorak HF, Jaminet SC
TM4SF1: a new vascular therapeutic target in cancer. Angiogenesis. 2014 Oct; 17(4):897-907.
TM4SF1: a new vascular therapeutic target in cancer.
Melo RC, Morgan E, Monahan-Earley R, Dvorak AM, Weller PF
Pre-embedding immunogold labeling to optimize protein localization at subcellular compartments and membrane microdomains of leukocytes. Nat Protoc. 2014 Oct; 9(10):2382-94.
Pre-embedding immunogold labeling to optimize protein localization at subcellular compartments and membrane microdomains of leukocytes.
Sciuto TE, Merley A, Lin CI, Richardson D, Liu Y, Li D, Dvorak AM, Dvorak HF, Jaminet SC
Biochemical and biophysical research communications
Intracellular distribution of TM4SF1 and internalization of TM4SF1-antibody complex in vascular endothelial cells. Biochem Biophys Res Commun. 2015 Sep 25; 465(3):338-43.
Intracellular distribution of TM4SF1 and internalization of TM4SF1-antibody complex in vascular endothelial cells.
Yuan L, Chan GC, Beeler D, Janes L, Spokes KC, Dharaneeswaran H, Mojiri A, Adams WJ, Sciuto T, Garcia-Cardeña G, Molema G, Kang PM, Jahroudi N, Marsden PA, Dvorak A, Regan ER, Aird WC
A role of stochastic phenotype switching in generating mosaic endothelial cell heterogeneity. Nat Commun. 2016 Jan 08; 7:10160.
A role of stochastic phenotype switching in generating mosaic endothelial cell heterogeneity.
Carmo LA, Bonjour K, Ueki S, Neves JS, Liu L, Spencer LA, Dvorak AM, Weller PF, Melo RC
CD63 is tightly associated with intracellular, secretory events chaperoning piecemeal degranulation and compound exocytosis in human eosinophils. J Leukoc Biol. 2016 08; 100(2):391-401.
CD63 is tightly associated with intracellular, secretory events chaperoning piecemeal degranulation and compound exocytosis in human eosinophils.
PATHWAY(S) OF LEUKOCYTE EXTRAVASATION IN INFLAMMATION
Spatial and Temporal Regulation of Angiogenesis
Dias FF, Amaral KB, Carmo LA, Shamri R, Dvorak AM, Weller PF, Melo RC
Human Eosinophil Leukocytes Express Protein Disulfide Isomerase in Secretory Granules and Vesicles: Ultrastructural Studies. J Histochem Cytochem. 2014 Jun; 62(6):450-459.
Human Eosinophil Leukocytes Express Protein Disulfide Isomerase in Secretory Granules and Vesicles: Ultrastructural Studies.
Pathways of macromolecular tracer transport across venules and small veins. Structural basis for the hyperpermeability of tumor blood vessels. Lab Invest. 1992 Nov; 67(5):596-607.
Pathways of macromolecular tracer transport across venules and small veins. Structural basis for the hyperpermeability of tumor blood vessels.
Dvorak AM, Schroeder JT, MacGlashan DW, Bryan KP, Morgan ES, Lichtenstein LM, MacDonald SM
The Journal of allergy and clinical immunology
Comparative ultrastructural morphology of human basophils stimulated to release histamine by anti-IgE, recombinant IgE-dependent histamine-releasing factor, or monocyte chemotactic protein-1. J Allergy Clin Immunol. 1996 Aug; 98(2):355-70.
Comparative ultrastructural morphology of human basophils stimulated to release histamine by anti-IgE, recombinant IgE-dependent histamine-releasing factor, or monocyte chemotactic protein-1.
Dvorak AM, Morgan E, Schleimer RP, Ryeom SW, Lichtenstein LM, Weller PF
Ultrastructural immunogold localization of prostaglandin endoperoxide synthase (cyclooxygenase) to non-membrane-bound cytoplasmic lipid bodies in human lung mast cells, alveolar macrophages, type II pneumocytes, and neutrophils. J Histochem Cytochem. 1992 Jun; 40(6):759-69.
Ultrastructural immunogold localization of prostaglandin endoperoxide synthase (cyclooxygenase) to non-membrane-bound cytoplasmic lipid bodies in human lung mast cells, alveolar macrophages, type II pneumocytes, and neutrophils.
Vesicular transport of histamine in stimulated human basophils. Blood. 1996 Dec 01; 88(11):4090-101.
Vesicular transport of histamine in stimulated human basophils.
The American Journal of dermatopathology
Multiple retiform hemangioendotheliomas. A low-grade angiosarcoma. Am J Dermatopathol. 1996 Dec; 18(6):606-10.
Multiple retiform hemangioendotheliomas. A low-grade angiosarcoma.
Calibration and standardization of microwave ovens for fixation of brain and peripheral nerve tissue. Methods. 1998 Jun; 15(2):107-17.
Calibration and standardization of microwave ovens for fixation of brain and peripheral nerve tissue.
Histamine content and secretion in basophils and mast cells. Prog Histochem Cytochem. 1998; 33(3-4):III-IX, 169-320.
Histamine content and secretion in basophils and mast cells.
Dvorak AM, Morgan ES, Lichtenstein LM, Weller PF, Schleimer RP
RNA is closely associated with human mast cell secretory granules, suggesting a role(s) for granules in synthetic processes. J Histochem Cytochem. 2000 Jan; 48(1):1-12.
RNA is closely associated with human mast cell secretory granules, suggesting a role(s) for granules in synthetic processes.
Melo RC, Spencer LA, Perez SA, Ghiran I, Dvorak AM, Weller PF
Human eosinophils secrete preformed, granule-stored interleukin-4 through distinct vesicular compartments. Traffic. 2005 Nov; 6(11):1047-57.
Human eosinophils secrete preformed, granule-stored interleukin-4 through distinct vesicular compartments.
Ultrastructural detection of histamine in human mast cells developing from cord blood cells cultured with human or murine recombinant c-kit ligands. Int Arch Allergy Immunol. 1996 Nov; 111(3):238-44.
Ultrastructural detection of histamine in human mast cells developing from cord blood cells cultured with human or murine recombinant c-kit ligands.
Cell biology of the basophil. Int Rev Cytol. 1998; 180:87-236.
Weller PF, Monahan-Earley RA, Dvorak HF, Dvorak AM
Cytoplasmic lipid bodies of human eosinophils. Subcellular isolation and analysis of arachidonate incorporation. Am J Pathol. 1991 Jan; 138(1):141-8.
Cytoplasmic lipid bodies of human eosinophils. Subcellular isolation and analysis of arachidonate incorporation.
Human basophil recovery from secretion. A review emphasizing the distribution of Charcot-Leyden crystal protein in cells stained with the postfixation electron-dense tracer, cationized ferritin. Histol Histopathol. 1996 Jul; 11(3):711-28.
Human basophil recovery from secretion. A review emphasizing the distribution of Charcot-Leyden crystal protein in cells stained with the postfixation electron-dense tracer, cationized ferritin.
Wimazal F, Sperr WR, Horny HP, Carroll V, Binder BR, Fonatsch C, Walchshofer S, Födinger M, Schwarzinger I, Samorapoompichit P, Chott A, Dvorak AM, Lechner K, Valent P
Hyperfibrinolysis in a case of myelodysplastic syndrome with leukemic spread of mast cells. Am J Hematol. 1999 May; 61(1):66-77.
Hyperfibrinolysis in a case of myelodysplastic syndrome with leukemic spread of mast cells.
Dvorak AM, McLeod RS, Onderdonk A, Monahan-Earley RA, Cullen JB, Antonioli DA, Morgan E, Blair JE, Estrella P, Cisneros RL
Ultrastructural evidence for piecemeal and anaphylactic degranulation of human gut mucosal mast cells in vivo. Int Arch Allergy Immunol. 1992; 99(1):74-83.
Ultrastructural evidence for piecemeal and anaphylactic degranulation of human gut mucosal mast cells in vivo.
Pettersson A, Nagy JA, Brown LF, Sundberg C, Morgan E, Jungles S, Carter R, Krieger JE, Manseau EJ, Harvey VS, Eckelhoefer IA, Feng D, Dvorak AM, Mulligan RC, Dvorak HF
Heterogeneity of the angiogenic response induced in different normal adult tissues by vascular permeability factor/vascular endothelial growth factor. Lab Invest. 2000 Jan; 80(1):99-115.
Heterogeneity of the angiogenic response induced in different normal adult tissues by vascular permeability factor/vascular endothelial growth factor.
Pediatric pathology & laboratory medicine : journal of the Society for Pediatric Pathology, affiliated with the International Paediatric Pathology Association
Human eosinophils are not pigment-laden macrophages in Pseudomelanosis duodeni. Pediatr Pathol Lab Med. 1997 Nov-Dec; 17(6):987-9.
Human eosinophils are not pigment-laden macrophages in Pseudomelanosis duodeni.
Platelets exit venules by a transcellular pathway at sites of F-met peptide-induced acute inflammation in guinea pigs. Int Arch Allergy Immunol. 1998 Jul; 116(3):188-95.
Platelets exit venules by a transcellular pathway at sites of F-met peptide-induced acute inflammation in guinea pigs.
Feng D, Flaumenhaft R, Bandeira-Melo C, Weller P, Dvorak A
Ultrastructural localization of vesicle-associated membrane protein(s) to specialized membrane structures in human pericytes, vascular smooth muscle cells, endothelial cells, neutrophils, and eosinophils. J Histochem Cytochem. 2001 Mar; 49(3):293-304.
Ultrastructural localization of vesicle-associated membrane protein(s) to specialized membrane structures in human pericytes, vascular smooth muscle cells, endothelial cells, neutrophils, and eosinophils.
Ultrastructural immunogold cytochemistry with autoimmune human sera and an antibody to uridine implicate human mast cell granules in RNA biology. Histochem J. 2000 Nov; 32(11):685-96.
Ultrastructural immunogold cytochemistry with autoimmune human sera and an antibody to uridine implicate human mast cell granules in RNA biology.
Feng D, Crane K, Rozenvayn N, Dvorak AM, Flaumenhaft R
Subcellular distribution of 3 functional platelet SNARE proteins: human cellubrevin, SNAP-23, and syntaxin 2. Blood. 2002 Jun 01; 99(11):4006-14.
Subcellular distribution of 3 functional platelet SNARE proteins: human cellubrevin, SNAP-23, and syntaxin 2.
Nagy JA, Chang SH, Shih SC, Dvorak AM, Dvorak HF
Heterogeneity of the tumor vasculature. Semin Thromb Hemost. 2010 Apr; 36(3):321-31.
Dienstag JL, Rhodes AR, Bhan AK, Dvorak AM, Mihm MC, Wands JR
Urticaria associated with acute viral hepatitis type B: studies of pathogenesis. Ann Intern Med. 1978 Jul; 89(1):34-40.
Urticaria associated with acute viral hepatitis type B: studies of pathogenesis.
Dvorak AM, Warner JA, Kissell S, Lichtenstein LM, MacGlashan DW
F-met peptide-induced degranulation of human basophils. Lab Invest. 1991 Feb; 64(2):234-53.
F-met peptide-induced degranulation of human basophils.
The mouse basophil, a rare and rarely recognized granulocyte. Blood. 2000 Aug 15; 96(4):1616-7.
The mouse basophil, a rare and rarely recognized granulocyte.
Dvorak AM, MacGlashan DW, Warner JA, Letourneau L, Morgan ES, Lichtenstein LM, Ackerman SJ
Vesicular transport of Charcot-Leyden crystal protein in f-Met peptide-stimulated human basophils. Int Arch Allergy Immunol. 1997 Aug; 113(4):465-77.
Vesicular transport of Charcot-Leyden crystal protein in f-Met peptide-stimulated human basophils.
Dvorak AM, Costa JJ, Morgan ES, Monahan-Earley RA, Galli SJ
Diamine oxidase-gold ultrastructural localization of histamine in human skin biopsies containing mast cells stimulated to degranulate in vivo by exposure to recombinant human stem cell factor. Blood. 1997 Oct 15; 90(8):2893-900.
Diamine oxidase-gold ultrastructural localization of histamine in human skin biopsies containing mast cells stimulated to degranulate in vivo by exposure to recombinant human stem cell factor.
Dvorak AM, Warner JA, Morgan E, Kissell-Rainville S, Lichtenstein LM, MacGlashan DW
An ultrastructural analysis of tumor-promoting phorbol diester-induced degranulation of human basophils. Am J Pathol. 1992 Dec; 141(6):1309-22.
An ultrastructural analysis of tumor-promoting phorbol diester-induced degranulation of human basophils.
Immunocytochemical localization of histamine in secretory granules of rat peritoneal mast cells with conventional or rapid microwave fixation and an ultrastructural post-embedding immunogold technique. J Histochem Cytochem. 1992 Sep; 40(9):1247-56.
Immunocytochemical localization of histamine in secretory granules of rat peritoneal mast cells with conventional or rapid microwave fixation and an ultrastructural post-embedding immunogold technique.
The case for extending storage and secretion functions of human mast cell granules to include synthesis. Prog Histochem Cytochem. 2002; 37(3):231-318.
The case for extending storage and secretion functions of human mast cell granules to include synthesis.
Brown LF, Detmar M, Claffey K, Nagy JA, Feng D, Dvorak AM, Dvorak HF
Vascular permeability factor/vascular endothelial growth factor: a multifunctional angiogenic cytokine. EXS. 1997; 79:233-69.
Vascular permeability factor/vascular endothelial growth factor: a multifunctional angiogenic cytokine.
A role for vesicles in human basophil secretion. Cell Tissue Res. 1998 Jul; 293(1):1-22.
A role for vesicles in human basophil secretion.
Ultrastructural studies define soluble macromolecular, particulate, and cellular transendothelial cell pathways in venules, lymphatic vessels, and tumor-associated microvessels in man and animals. Microsc Res Tech. 2002 Jun 01; 57(5):289-326.
Ultrastructural studies define soluble macromolecular, particulate, and cellular transendothelial cell pathways in venules, lymphatic vessels, and tumor-associated microvessels in man and animals.
Ribosomes and secretory granules in human mast cells: close associations demonstrated by staining with a chelating agent. Immunol Rev. 2001 Feb; 179:94-101.
Ribosomes and secretory granules in human mast cells: close associations demonstrated by staining with a chelating agent.
Seder RA, Paul WE, Dvorak AM, Sharkis SJ, Kagey-Sobotka A, Niv Y, Finkelman FD, Barbieri SA, Galli SJ, Plaut M
Mouse splenic and bone marrow cell populations that express high-affinity Fc epsilon receptors and produce interleukin 4 are highly enriched in basophils. Proc Natl Acad Sci U S A. 1991 Apr 01; 88(7):2835-9.
Mouse splenic and bone marrow cell populations that express high-affinity Fc epsilon receptors and produce interleukin 4 are highly enriched in basophils.
Yang L, Froio RM, Sciuto TE, Dvorak AM, Alon R, Luscinskas FW
ICAM-1 regulates neutrophil adhesion and transcellular migration of TNF-alpha-activated vascular endothelium under flow. Blood. 2005 Jul 15; 106(2):584-92.
ICAM-1 regulates neutrophil adhesion and transcellular migration of TNF-alpha-activated vascular endothelium under flow.
Images in clinical medicine. Mesothelioma. N Engl J Med. 2001 Aug 09; 345(6):424.
Images in clinical medicine. Mesothelioma.
Dvorak AM, Furitsu T, Kissell-Rainville S, Ishizaka T
Ultrastructural identification of human mast cells resembling skin mast cells stimulated to develop in long-term human cord blood mononuclear cells cultured with 3T3 murine skin fibroblasts. J Leukoc Biol. 1992 Jun; 51(6):557-69.
Ultrastructural identification of human mast cells resembling skin mast cells stimulated to develop in long-term human cord blood mononuclear cells cultured with 3T3 murine skin fibroblasts.
Crohn's disease: electron microscopic studies. Pathol Annu. 1979; 14 Pt 2:259-306.
Crohn's disease: electron microscopic studies.
Jabara HH, Ackerman SJ, Vercelli D, Yokota T, Arai K, Abrams J, Dvorak AM, Lavigne MC, Banchereau J, De Vries J
Induction of interleukin-4-dependent IgE synthesis and interleukin-5-dependent eosinophil differentiation by supernatants of a human helper T-cell clone. J Clin Immunol. 1988 Nov; 8(6):437-46.
Induction of interleukin-4-dependent IgE synthesis and interleukin-5-dependent eosinophil differentiation by supernatants of a human helper T-cell clone.
Crohn's disease: a scanning electron microscopic study. Hum Pathol. 1979 Mar; 10(2):165-77.
Crohn's disease: a scanning electron microscopic study.
Dvorak AM, Massey W, Warner J, Kissell S, Kagey-Sobotka A, Lichtenstein LM
IgE-mediated anaphylactic degranulation of isolated human skin mast cells. Blood. 1991 Feb 01; 77(3):569-78.
IgE-mediated anaphylactic degranulation of isolated human skin mast cells.
Cancer cells (Cold Spring Harbor, N.Y. : 1989)
Structure of solid tumors and their vasculature: implications for therapy with monoclonal antibodies. Cancer Cells. 1991 Mar; 3(3):77-85.
Structure of solid tumors and their vasculature: implications for therapy with monoclonal antibodies.
Melo RC, Spencer LA, Dvorak AM, Weller PF
Mechanisms of eosinophil secretion: large vesiculotubular carriers mediate transport and release of granule-derived cytokines and other proteins. J Leukoc Biol. 2008 Feb; 83(2):229-36.
Mechanisms of eosinophil secretion: large vesiculotubular carriers mediate transport and release of granule-derived cytokines and other proteins.
Ultrastructural localization of osteopontin immunoreactivity in phagolysosomes and secretory granules of cells in human intestine. Histochem J. 1997 Nov-Dec; 29(11-12):801-12.
Ultrastructural localization of osteopontin immunoreactivity in phagolysosomes and secretory granules of cells in human intestine.
Yu W, Bozza PT, Tzizik DM, Gray JP, Cassara J, Dvorak AM, Weller PF
Co-compartmentalization of MAP kinases and cytosolic phospholipase A2 at cytoplasmic arachidonate-rich lipid bodies. Am J Pathol. 1998 Mar; 152(3):759-69.
Co-compartmentalization of MAP kinases and cytosolic phospholipase A2 at cytoplasmic arachidonate-rich lipid bodies.
Images in allergy and immunology. Mast cell apoptosis. Int Arch Allergy Immunol. 1999 May; 119(1):72.
Images in allergy and immunology. Mast cell apoptosis.
Petrogiannis-Haliotis T, Sakoulas G, Kirby J, Koralnik IJ, Dvorak AM, Monahan-Earley R, DE Girolami PC, DE Girolami U, Upton M, Major EO, Pfister LA, Joseph JT
BK-related polyomavirus vasculopathy in a renal-transplant recipient. N Engl J Med. 2001 Oct 25; 345(17):1250-5.
BK-related polyomavirus vasculopathy in a renal-transplant recipient.
Nagy JA, Feng D, Vasile E, Wong WH, Shih SC, Dvorak AM, Dvorak HF
Permeability properties of tumor surrogate blood vessels induced by VEGF-A. Lab Invest. 2006 Aug; 86(8):767-80.
Permeability properties of tumor surrogate blood vessels induced by VEGF-A.
Onderdonk AB, Dvorak AM, Cisneros RL, McLeod RS, Antionoli D, Silen W, Blair JE, Monahan-Earley RA, Cullen J, Cohen Z
Microbiologic assessment of tissue biopsy samples from ileal pouch patients. J Clin Microbiol. 1992 Feb; 30(2):312-7.
Microbiologic assessment of tissue biopsy samples from ileal pouch patients.
Sundberg C, Nagy JA, Brown LF, Feng D, Eckelhoefer IA, Manseau EJ, Dvorak AM, Dvorak HF
Glomeruloid microvascular proliferation follows adenoviral vascular permeability factor/vascular endothelial growth factor-164 gene delivery. Am J Pathol. 2001 Mar; 158(3):1145-60.
Glomeruloid microvascular proliferation follows adenoviral vascular permeability factor/vascular endothelial growth factor-164 gene delivery.
Nagy JA, Benjamin L, Zeng H, Dvorak AM, Dvorak HF
Vascular permeability, vascular hyperpermeability and angiogenesis. Angiogenesis. 2008; 11(2):109-19.
Vascular permeability, vascular hyperpermeability and angiogenesis.
Feng D, Nagy JA, Brekken RA, Pettersson A, Manseau EJ, Pyne K, Mulligan R, Thorpe PE, Dvorak HF, Dvorak AM
Ultrastructural localization of the vascular permeability factor/vascular endothelial growth factor (VPF/VEGF) receptor-2 (FLK-1, KDR) in normal mouse kidney and in the hyperpermeable vessels induced by VPF/VEGF-expressing tumors and adenoviral vectors. J Histochem Cytochem. 2000 Apr; 48(4):545-56.
Ultrastructural localization of the vascular permeability factor/vascular endothelial growth factor (VPF/VEGF) receptor-2 (FLK-1, KDR) in normal mouse kidney and in the hyperpermeable vessels induced by VPF/VEGF-expressing tumors and adenoviral vectors.
Ishizaka T, Dvorak AM, Conrad DH, Niebyl JR, Marquette JP, Ishizaka K
Morphologic and immunologic characterization of human basophils developed in cultures of cord blood mononuclear cells. J Immunol. 1985 Jan; 134(1):532-40.
Morphologic and immunologic characterization of human basophils developed in cultures of cord blood mononuclear cells.
Roblin RO, Hammond ME, Bensky ND, Dvorak AM, Dvorak HF, Black PH
Generation of macrophage migration inhibitory activity by plasminogen activators. Proc Natl Acad Sci U S A. 1977 Apr; 74(4):1570-4.
Generation of macrophage migration inhibitory activity by plasminogen activators.
Min B, Prout M, Hu-Li J, Zhu J, Jankovic D, Morgan ES, Urban JF, Dvorak AM, Finkelman FD, LeGros G, Paul WE
Basophils produce IL-4 and accumulate in tissues after infection with a Th2-inducing parasite. J Exp Med. 2004 Aug 16; 200(4):507-17.
Basophils produce IL-4 and accumulate in tissues after infection with a Th2-inducing parasite.
Flaumenhaft R, Dilks JR, Rozenvayn N, Monahan-Earley RA, Feng D, Dvorak AM
The actin cytoskeleton differentially regulates platelet alpha-granule and dense-granule secretion. Blood. 2005 May 15; 105(10):3879-87.
The actin cytoskeleton differentially regulates platelet alpha-granule and dense-granule secretion.
Ultrastructural analysis is necessary and sufficient for identification of basophils and mast cells. Chem Immunol Allergy. 2005; 85:10-67.
Ultrastructural analysis is necessary and sufficient for identification of basophils and mast cells.
Ultrastructural localization of histamine in human basophils and mast cells; changes associated with anaphylactic degranulation and recovery demonstrated with a diamine oxidase-gold probe. Allergy. 1997; 52(34 Suppl):14-24.
Ultrastructural localization of histamine in human basophils and mast cells; changes associated with anaphylactic degranulation and recovery demonstrated with a diamine oxidase-gold probe.
Eosinophils or large granular lymphocytes. Blood. 1992 Nov 01; 80(9):2429-31.
Eosinophils or large granular lymphocytes.
Flaumenhaft R, Rozenvayn N, Feng D, Dvorak AM
SNAP-23 and syntaxin-2 localize to the extracellular surface of the platelet plasma membrane. Blood. 2007 Sep 01; 110(5):1492-501.
SNAP-23 and syntaxin-2 localize to the extracellular surface of the platelet plasma membrane.
Carman CV, Sage PT, Sciuto TE, de la Fuente MA, Geha RS, Ochs HD, Dvorak HF, Dvorak AM, Springer TA
Transcellular diapedesis is initiated by invasive podosomes. Immunity. 2007 Jun; 26(6):784-97.
Transcellular diapedesis is initiated by invasive podosomes.
Dvorak AM, Furitsu T, Estrella P, Ishizaka T
Human lung-derived mature mast cells cultured alone or with mouse 3T3 fibroblasts maintain an ultrastructural phenotype different from that of human mast cells that develop from human cord blood cells cultured with 3T3 fibroblasts. Am J Pathol. 1991 Dec; 139(6):1309-18.
Human lung-derived mature mast cells cultured alone or with mouse 3T3 fibroblasts maintain an ultrastructural phenotype different from that of human mast cells that develop from human cord blood cells cultured with 3T3 fibroblasts.
Human chorionic mast cells with numerous lipid bodies and a mixture of immature and mature granules are present in gastroschisis. Pediatr Pathol. 1991 Jul-Aug; 11(4):673-6.
Human chorionic mast cells with numerous lipid bodies and a mixture of immature and mature granules are present in gastroschisis.
Kuten A, Olumi A, Goldsmith J, Monahan-Earley RA, Dvorak AM, Genega EM
Pathologic quiz case. A symptomatic renal tumor. Juxtaglomerular cell tumor. Arch Pathol Lab Med. 2004 Sep; 128(9):e112-4.
Pathologic quiz case. A symptomatic renal tumor. Juxtaglomerular cell tumor.
Yano K, Gale D, Massberg S, Cheruvu PK, Monahan-Earley R, Morgan ES, Haig D, von Andrian UH, Dvorak AM, Aird WC
Phenotypic heterogeneity is an evolutionarily conserved feature of the endothelium. Blood. 2007 Jan 15; 109(2):613-5.
Phenotypic heterogeneity is an evolutionarily conserved feature of the endothelium.
Diamine oxidase-gold enzyme-affinity ultrastructural demonstration that human gut mucosal mast cells secrete histamine by piecemeal degranulation in vivo. J Allergy Clin Immunol. 1997 Jun; 99(6 Pt 1):812-20.
Diamine oxidase-gold enzyme-affinity ultrastructural demonstration that human gut mucosal mast cells secrete histamine by piecemeal degranulation in vivo.
Caveolae and vesiculo-vacuolar organelles in bovine capillary endothelial cells cultured with VPF/VEGF on floating Matrigel-collagen gels. J Histochem Cytochem. 1999 Feb; 47(2):159-67.
Caveolae and vesiculo-vacuolar organelles in bovine capillary endothelial cells cultured with VPF/VEGF on floating Matrigel-collagen gels.
Weller PF, Ryeom SW, Picard ST, Ackerman SJ, Dvorak AM
Cytoplasmic lipid bodies of neutrophils: formation induced by cis-unsaturated fatty acids and mediated by protein kinase C. J Cell Biol. 1991 Apr; 113(1):137-46.
Cytoplasmic lipid bodies of neutrophils: formation induced by cis-unsaturated fatty acids and mediated by protein kinase C.
Nagy JA, Brown LF, Senger DR, Lanir N, Van de Water L, Dvorak AM, Dvorak HF
Pathogenesis of tumor stroma generation: a critical role for leaky blood vessels and fibrin deposition. Biochim Biophys Acta. 1989 Feb; 948(3):305-26.
Pathogenesis of tumor stroma generation: a critical role for leaky blood vessels and fibrin deposition.
RNA is closely associated with human mast cell lipid bodies. Histol Histopathol. 2003 07; 18(3):943-68.
RNA is closely associated with human mast cell lipid bodies.
Melo RC, Paganoti GF, Dvorak AM, Weller PF
The internal architecture of leukocyte lipid body organelles captured by three-dimensional electron microscopy tomography. PLoS One. 2013; 8(3):e59578.
The internal architecture of leukocyte lipid body organelles captured by three-dimensional electron microscopy tomography.
Cyclooxygenase, a key enzyme family for production of prostaglandins, is present in human mast cell lipid bodies. Chem Immunol Allergy. 2005; 85:68-71.
Cyclooxygenase, a key enzyme family for production of prostaglandins, is present in human mast cell lipid bodies.
Galli SJ, Arizono N, Murakami T, Dvorak AM, Fox JG
Development of large numbers of mast cells at sites of idiopathic chronic dermatitis in genetically mast cell-deficient WBB6F1-W/Wv mice. Blood. 1987 Jun; 69(6):1661-6.
Development of large numbers of mast cells at sites of idiopathic chronic dermatitis in genetically mast cell-deficient WBB6F1-W/Wv mice.
Dvorak HF, Orenstein NS, Galli SJ, Dvorak AM
Plasminogen activator of guinea pig basophils. A protease probably localized to the cell surface. Monogr Allergy. 1979; 14:249-52.
Plasminogen activator of guinea pig basophils. A protease probably localized to the cell surface.
The basophil. Its morphology, biochemistry, motility, release reactions, recovery, and role in the inflammatory responses of IgE-mediated and cell-mediated origin. Arch Pathol Lab Med. 1979 Oct; 103(11):551-7.
The basophil. Its morphology, biochemistry, motility, release reactions, recovery, and role in the inflammatory responses of IgE-mediated and cell-mediated origin.
Congenital systemic candidiasis. Report of a case. N Engl J Med. 1966 Mar 10; 274(10):540-3.
Congenital systemic candidiasis. Report of a case.
Dvorak AM, Cable WJ, Osage JE, Kolodny EH
Diagnostic electron microscopy. II. Fabry's disease: use of biopsies from uninvolved skin. Acute and chronic changes involving the microvasculature and small unmyelinated nerves. Pathol Annu. 1981; 16 Pt 1:139-58.
Diagnostic electron microscopy. II. Fabry's disease: use of biopsies from uninvolved skin. Acute and chronic changes involving the microvasculature and small unmyelinated nerves.
Application of microwave fixation techniques in pathology to neuroscience studies: a review. J Neurosci Methods. 1994 Dec; 55(2):173-82.
Application of microwave fixation techniques in pathology to neuroscience studies: a review.
Paul CC, Ackerman SJ, Mahrer S, Tolbert M, Dvorak AM, Baumann MA
Cytokine induction of granule protein synthesis in an eosinophil-inducible human myeloid cell line, AML14. J Leukoc Biol. 1994 Jul; 56(1):74-9.
Cytokine induction of granule protein synthesis in an eosinophil-inducible human myeloid cell line, AML14.
Ultrastructural immunogold localization of tumor necrosis factor-alpha to the cytoplasmic granules of rat peritoneal mast cells with rapid microwave fixation. J Allergy Clin Immunol. 1994 Sep; 94(3 Pt 1):531-6.
Ultrastructural immunogold localization of tumor necrosis factor-alpha to the cytoplasmic granules of rat peritoneal mast cells with rapid microwave fixation.
A review of rapid microwave fixation technology: its expanding niche in morphologic studies. Scanning. 1993 Mar-Apr; 15(2):58-66.
A review of rapid microwave fixation technology: its expanding niche in morphologic studies.
Ultrastructural morphology of human mast cell progenitors in sequential cocultures of cord blood cells and fibroblasts. Int Arch Allergy Immunol. 1993; 100(3):219-29.
Ultrastructural morphology of human mast cell progenitors in sequential cocultures of cord blood cells and fibroblasts.
Hammel I, Dvorak AM, Peters SP, Schulman ES, Dvorak HF, Lichtenstein LM, Galli SJ
Differences in the volume distributions of human lung mast cell granules and lipid bodies: evidence that the size of these organelles is regulated by distinct mechanisms. J Cell Biol. 1985 May; 100(5):1488-92.
Differences in the volume distributions of human lung mast cell granules and lipid bodies: evidence that the size of these organelles is regulated by distinct mechanisms.
Dvorak HF, Dvorak AM, Simpson BA, Richerson HB, Leskowitz S, Karnovsky MJ
Cutaneous basophil hypersensitivity. II. A light and electron microscopic description. J Exp Med. 1970 Sep 01; 132(3):558-82.
Cutaneous basophil hypersensitivity. II. A light and electron microscopic description.
Morphologic changes in draining lymph nodes and in lymphocyte cultures after sensitization with complete or incomplete Freund's adjuvant. Correlation with immunologic events in vivo and in culture. J Immunol. 1971 Aug; 107(2):422-35.
Morphologic changes in draining lymph nodes and in lymphocyte cultures after sensitization with complete or incomplete Freund's adjuvant. Correlation with immunologic events in vivo and in culture.
Dvorak AM, Newball HH, Dvorak HF, Lichtenstein LM
Antigen-induced IgE-mediated degranulation of human basophils. Lab Invest. 1980 Aug; 43(2):126-39.
Antigen-induced IgE-mediated degranulation of human basophils.
Dvorak AM, Lett-Brown M, Thueson D, Grant JA
Complement-induced degranulation of human basophils. J Immunol. 1981 Feb; 126(2):523-8.
Complement-induced degranulation of human basophils.
Dvorak HF, Dvorak AM, Manseau EJ, Wiberg L, Churchill WH
Fibrin gel investment associated with line 1 and line 10 solid tumor growth, angiogenesis, and fibroplasia in guinea pigs. Role of cellular immunity, myofibroblasts, microvascular damage, and infarction in line 1 tumor regression. J Natl Cancer Inst. 1979 Jun; 62(6):1459-72.
Fibrin gel investment associated with line 1 and line 10 solid tumor growth, angiogenesis, and fibroplasia in guinea pigs. Role of cellular immunity, myofibroblasts, microvascular damage, and infarction in line 1 tumor regression.
Katz LM, Frank JE, Dvorak A, Finch A, Szymanowski A, Gordon CJ
Independence of brain and trunk temperature during hypothermic preconditioning in rats. J Neurosci Methods. 2009 May 15; 179(2):179-83.
Independence of brain and trunk temperature during hypothermic preconditioning in rats.
Ultrastructural criteria for identification of mast cells and basophils in humans, guinea pigs, and mice. Am Rev Respir Dis. 1983 Aug; 128(2 Pt 2):S49-52.
Ultrastructural criteria for identification of mast cells and basophils in humans, guinea pigs, and mice.
Dvorak AM, Hammel I, Schulman ES, Peters SP, MacGlashan DW, Schleimer RP, Newball HH, Pyne K, Dvorak HF, Lichtenstein LM
Differences in the behavior of cytoplasmic granules and lipid bodies during human lung mast cell degranulation. J Cell Biol. 1984 Nov; 99(5):1678-87.
Differences in the behavior of cytoplasmic granules and lipid bodies during human lung mast cell degranulation.
Dvorak AM, Hammond ME, Morgan ES, Dvorak HF
Ultrastructural studies of macrophages: in vitro removal of cell coat with macrophage inhibition factor (MIF)-containing lymphocyte culture supernatants; chloroform extraction, phospholipase digestion, and autoradiographic studies. J Reticuloendothel Soc. 1980 Feb; 27(2):119-42.
Ultrastructural studies of macrophages: in vitro removal of cell coat with macrophage inhibition factor (MIF)-containing lymphocyte culture supernatants; chloroform extraction, phospholipase digestion, and autoradiographic studies.
Nagy JA, Morgan ES, Herzberg KT, Manseau EJ, Dvorak AM, Dvorak HF
Pathogenesis of ascites tumor growth: angiogenesis, vascular remodeling, and stroma formation in the peritoneal lining. Cancer Res. 1995 Jan 15; 55(2):376-85.
Pathogenesis of ascites tumor growth: angiogenesis, vascular remodeling, and stroma formation in the peritoneal lining.
Mitsui H, Furitsu T, Dvorak AM, Irani AM, Schwartz LB, Inagaki N, Takei M, Ishizaka K, Zsebo KM, Gillis S
Development of human mast cells from umbilical cord blood cells by recombinant human and murine c-kit ligand. Proc Natl Acad Sci U S A. 1993 Jan 15; 90(2):735-9.
Development of human mast cells from umbilical cord blood cells by recombinant human and murine c-kit ligand.
Lipid bodies: intracellular sites for eicosanoid formation. J Allergy Clin Immunol. 1994 Dec; 94(6 Pt 2):1151-6.
Lipid bodies: intracellular sites for eicosanoid formation.
Abundant eosinophilic globules in a series of cases of angiosarcoma of the liver in childhood. Pediatr Pathol. 1993 Jul-Aug; 13(4):541-5.
Abundant eosinophilic globules in a series of cases of angiosarcoma of the liver in childhood.
Feng D, Nagy JA, Hipp J, Dvorak HF, Dvorak AM
Vesiculo-vacuolar organelles and the regulation of venule permeability to macromolecules by vascular permeability factor, histamine, and serotonin. J Exp Med. 1996 May 01; 183(5):1981-6.
Vesiculo-vacuolar organelles and the regulation of venule permeability to macromolecules by vascular permeability factor, histamine, and serotonin.
Golightly LM, Thomas LL, Dvorak AM, Ackerman SJ
Charcot-Leyden crystal protein in the degranulation and recovery of activated basophils. J Leukoc Biol. 1992 Apr; 51(4):386-92.
Charcot-Leyden crystal protein in the degranulation and recovery of activated basophils.
Dvorak AM, Costa JJ, Monahan-Earley RA, Fox P, Galli SJ
Ultrastructural analysis of human skin biopsy specimens from patients receiving recombinant human stem cell factor: subcutaneous injection of rhSCF induces dermal mast cell degranulation and granulocyte recruitment at the injection site. J Allergy Clin Immunol. 1998 Jun; 101(6 Pt 1):793-806.
Ultrastructural analysis of human skin biopsy specimens from patients receiving recombinant human stem cell factor: subcutaneous injection of rhSCF induces dermal mast cell degranulation and granulocyte recruitment at the injection site.
Martinelli R, Kamei M, Sage PT, Massol R, Varghese L, Sciuto T, Toporsian M, Dvorak AM, Kirchhausen T, Springer TA, Carman CV
Release of cellular tension signals self-restorative ventral lamellipodia to heal barrier micro-wounds. J Cell Biol. 2013 Apr 29; 201(3):449-65.
Release of cellular tension signals self-restorative ventral lamellipodia to heal barrier micro-wounds.
Ribonuclease-gold labels chondroitin sulphate in guinea pig basophil granules. Histochem J. 1998 Aug; 30(8):603-8.
Ribonuclease-gold labels chondroitin sulphate in guinea pig basophil granules.
Basophils and mast cells: piecemeal degranulation in situ and ex vivo: a possible mechanism for cytokine-induced function in disease. Immunol Ser. 1992; 57:169-271.
Basophils and mast cells: piecemeal degranulation in situ and ex vivo: a possible mechanism for cytokine-induced function in disease.
Morphologic mast cell cycles. Cell Immunol. 1987 Mar; 105(1):199-204.
Nagy JA, Shih SC, Wong WH, Dvorak AM, Dvorak HF
Chapter 3. The adenoviral vector angiogenesis/lymphangiogenesis assay. Methods Enzymol. 2008; 444:43-64.
Chapter 3. The adenoviral vector angiogenesis/lymphangiogenesis assay.
Dvorak HF, Harvey VS, Estrella P, Brown LF, McDonagh J, Dvorak AM
Fibrin containing gels induce angiogenesis. Implications for tumor stroma generation and wound healing. Lab Invest. 1987 Dec; 57(6):673-86.
Fibrin containing gels induce angiogenesis. Implications for tumor stroma generation and wound healing.
One-micron plastic sections of human peripheral blood and bone marrow specimens and peroxidase cytochemistry: use in the differential diagnosis of acute leukemias. Pathol Annu. 1985; 20 Pt 1:383-401.
One-micron plastic sections of human peripheral blood and bone marrow specimens and peroxidase cytochemistry: use in the differential diagnosis of acute leukemias.
Sage PT, Varghese LM, Martinelli R, Sciuto TE, Kamei M, Dvorak AM, Springer TA, Sharpe AH, Carman CV
Antigen recognition is facilitated by invadosome-like protrusions formed by memory/effector T cells. J Immunol. 2012 Apr 15; 188(8):3686-99.
Antigen recognition is facilitated by invadosome-like protrusions formed by memory/effector T cells.
Dvorak A, Tilley AE, Shaykhiev R, Wang R, Crystal RG
American journal of respiratory cell and molecular biology
Do airway epithelium air-liquid cultures represent the in vivo airway epithelium transcriptome? Am J Respir Cell Mol Biol. 2011 Apr; 44(4):465-73.
Do airway epithelium air-liquid cultures represent the in vivo airway epithelium transcriptome?
Ueki S, Melo RC, Ghiran I, Spencer LA, Dvorak AM, Weller PF
Eosinophil extracellular DNA trap cell death mediates lytic release of free secretion-competent eosinophil granules in humans. Blood. 2013 Mar 14; 121(11):2074-83.
Eosinophil extracellular DNA trap cell death mediates lytic release of free secretion-competent eosinophil granules in humans.
Sitohy B, Chang S, Sciuto TE, Masse E, Shen M, Kang PM, Jaminet SC, Benjamin LE, Bhatt RS, Dvorak AM, Nagy JA, Dvorak HF
Early Actions of Anti-Vascular Endothelial Growth Factor/Vascular Endothelial Growth Factor Receptor Drugs on Angiogenic Blood Vessels. Am J Pathol. 2017 Oct; 187(10):2337-2347.
Early Actions of Anti-Vascular Endothelial Growth Factor/Vascular Endothelial Growth Factor Receptor Drugs on Angiogenic Blood Vessels.
Gang DL, Long JC, Zamecnik PC, Chi SY, Dvorak AM
Electron microscopy of Hodgkin's disease tissue cultures. Cancer. 1979 Aug; 44(2):543-57.
Electron microscopy of Hodgkin's disease tissue cultures.
Dvorak HF, Senger DR, Dvorak AM, Harvey VS, McDonagh J
Regulation of extravascular coagulation by microvascular permeability. Science. 1985 Mar 01; 227(4690):1059-61.
Regulation of extravascular coagulation by microvascular permeability.
Dvorak HF, Mihm MC, Dvorak AM, Johnson RA, Manseau EJ, Morgan E, Colvin RB
Morphology of delayed type hypersensitivity reactions in man. I. Quantitative description of the inflammatory response. Lab Invest. 1974 Aug; 31(2):111-30.
Morphology of delayed type hypersensitivity reactions in man. I. Quantitative description of the inflammatory response.
Findlay SR, Dvorak AM, Kagey-Sobotka A, Lichtenstein LM
Hyperosmolar triggering of histamine release from human basophils. J Clin Invest. 1981 Jun; 67(6):1604-13.
Hyperosmolar triggering of histamine release from human basophils.
Dvorak AM, Furitsu T, Letourneau L, Ishizaka T, Ackerman SJ
Mature eosinophils stimulated to develop in human cord blood mononuclear cell cultures supplemented with recombinant human interleukin-5. Part I. Piecemeal degranulation of specific granules and distribution of Charcot-Leyden crystal protein. Am J Pathol. 1991 Jan; 138(1):69-82.
Mature eosinophils stimulated to develop in human cord blood mononuclear cell cultures supplemented with recombinant human interleukin-5. Part I. Piecemeal degranulation of specific granules and distribution of Charcot-Leyden crystal protein.
Cable WJ, Dvorak AM, Osage JE, Kolodny EH
Fabry disease: significance of ultrastructural localization of lipid inclusions in dermal nerves. Neurology. 1982 Apr; 32(4):347-53.
Fabry disease: significance of ultrastructural localization of lipid inclusions in dermal nerves.
Dvorak AM, Roblin RO, Morgan ES, Dvorak HF
Ultrastructure of the cell coat of untransformed and simian virus 40-transformed fibroblasts. J Reticuloendothel Soc. 1979 Feb; 25(2):163-77.
Ultrastructure of the cell coat of untransformed and simian virus 40-transformed fibroblasts.
Rapid primary microwave-aldehyde and microwave-osmium fixation: improved detection of rat parotid acinar cell secretory granule alpha-amylase using a post-embedding immunogold ultrastructural morphometric analysis. J Histochem Cytochem. 1995 May; 43(5):515-23.
Rapid primary microwave-aldehyde and microwave-osmium fixation: improved detection of rat parotid acinar cell secretory granule alpha-amylase using a post-embedding immunogold ultrastructural morphometric analysis.
Different pathways of macromolecule extravasation from hyperpermeable tumor vessels. Microvasc Res. 2000 Jan; 59(1):24-37.
Different pathways of macromolecule extravasation from hyperpermeable tumor vessels.
Grant MA, Beeler DL, Spokes KC, Chen J, Dharaneeswaran H, Sciuto TE, Dvorak AM, Interlandi G, Lopez JA, Aird WC
Identification of extant vertebrate Myxine glutinosa VWF: evolutionary conservation of primary hemostasis. Blood. 2017 12 07; 130(23):2548-2558.
Identification of extant vertebrate Myxine glutinosa VWF: evolutionary conservation of primary hemostasis.
Benson EM, Giorgi JV, Dvorak AM, Galli SJ, Russell PS
Cloned "anomalous" killer cells derived from allogeneic mixed leukocyte culture. Cell Immunol. 1987 Jun; 107(1):201-18.
Cloned "anomalous" killer cells derived from allogeneic mixed leukocyte culture.
Furitsu T, Saito H, Dvorak AM, Schwartz LB, Irani AM, Burdick JF, Ishizaka K, Ishizaka T
Development of human mast cells in vitro. Proc Natl Acad Sci U S A. 1989 Dec; 86(24):10039-43.
Development of human mast cells in vitro.
Login GR, Yang J, Bryan KP, Digenis EC, McBride J, Elovic A, Quissell DO, Dvorak AM, Wong DT
Characterization of synthesis and storage of TGF-alpha in rat parotid acinar and intercalated duct cells. Am J Physiol. 1997 Mar; 272(3 Pt 1):G553-62.
Characterization of synthesis and storage of TGF-alpha in rat parotid acinar and intercalated duct cells.
Monahan-Earley RA, Isomura T, Garcia RI, Galli SJ, Dvorak HF, Dvorak AM
Nonspecific esterase activity expressed in Weibel-Palade bodies of cloned guinea pig aortic endothelial cells. J Histochem Cytochem. 1987 May; 35(5):531-9.
Nonspecific esterase activity expressed in Weibel-Palade bodies of cloned guinea pig aortic endothelial cells.
Structure of Freund's complete and incomplete adjuvants. Relation of adjuvanticity to structure. Immunology. 1974 Jul; 27(1):99-114.
Structure of Freund's complete and incomplete adjuvants. Relation of adjuvanticity to structure.
International review of experimental pathology
Expression of cell-mediated hypersensitivity in vivo--recent advances. Int Rev Exp Pathol. 1980; 21:119-94.
Expression of cell-mediated hypersensitivity in vivo--recent advances.
International journal of clinical & laboratory research
Ultrastructural analysis of the development of human basophils and mast cells in vitro. Int J Clin Lab Res. 1995; 25(1):7-24.
Ultrastructural analysis of the development of human basophils and mast cells in vitro.
Ultrastructure of human mast cells. Int Arch Allergy Immunol. 2002 Feb; 127(2):100-5.
Ultrastructural enzyme-affinity-gold and inhibitor-gold techniques identify subcellular sites of histamine and heparin in basophils and mast cells. Chem Immunol Allergy. 2005; 85:98-134.
Ultrastructural enzyme-affinity-gold and inhibitor-gold techniques identify subcellular sites of histamine and heparin in basophils and mast cells.
Wan HC, Melo RC, Jin Z, Dvorak AM, Weller PF
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Roles and origins of leukocyte lipid bodies: proteomic and ultrastructural studies. FASEB J. 2007 Jan; 21(1):167-78.
Roles and origins of leukocyte lipid bodies: proteomic and ultrastructural studies.
Dvorak AM, Weller PF, Monahan-Earley RA, Letourneau L, Ackerman SJ
Ultrastructural localization of Charcot-Leyden crystal protein (lysophospholipase) and peroxidase in macrophages, eosinophils, and extracellular matrix of the skin in the hypereosinophilic syndrome. Lab Invest. 1990 May; 62(5):590-607.
Ultrastructural localization of Charcot-Leyden crystal protein (lysophospholipase) and peroxidase in macrophages, eosinophils, and extracellular matrix of the skin in the hypereosinophilic syndrome.
Griffin JD, Ellman L, Long JC, Dvorak AM
Development of a histiocytic medullary reticulosis-like syndrome during the course of acute lymphocytic leukemia. Am J Med. 1978 May; 64(5):851-8.
Development of a histiocytic medullary reticulosis-like syndrome during the course of acute lymphocytic leukemia.
Schacht V, Ramirez MI, Hong YK, Hirakawa S, Feng D, Harvey N, Williams M, Dvorak AM, Dvorak HF, Oliver G, Detmar M
T1alpha/podoplanin deficiency disrupts normal lymphatic vasculature formation and causes lymphedema. EMBO J. 2003 Jul 15; 22(14):3546-56.
T1alpha/podoplanin deficiency disrupts normal lymphatic vasculature formation and causes lymphedema.
Images iin Allergy and Immunology. Mouse spleen basophils. Int Arch Allergy Immunol. 2004 Aug; 134(4):332-3.
Images iin Allergy and Immunology. Mouse spleen basophils.
Subcellular localization of the cytokines, basic fibroblast growth factor and tumor necrosis factor-alpha in mast cells. Chem Immunol Allergy. 2005; 85:72-88.
Subcellular localization of the cytokines, basic fibroblast growth factor and tumor necrosis factor-alpha in mast cells.
Tubman VN, Levine JE, Campagna DR, Monahan-Earley R, Dvorak AM, Neufeld EJ, Fleming MD
X-linked gray platelet syndrome due to a GATA1 Arg216Gln mutation. Blood. 2007 Apr 15; 109(8):3297-9.
X-linked gray platelet syndrome due to a GATA1 Arg216Gln mutation.
Feng J, Yano K, Monahan-Earley R, Morgan ES, Dvorak AM, Sellke FW, Aird WC
American journal of physiology. Regulatory, integrative and comparative physiology
Vascular bed-specific endothelium-dependent vasomomotor relaxation in the hagfish, Myxine glutinosa. Am J Physiol Regul Integr Comp Physiol. 2007 Aug; 293(2):R894-900.
Vascular bed-specific endothelium-dependent vasomomotor relaxation in the hagfish, Myxine glutinosa.
Rapid primary microwave-osmium fixation. I. Preservation of structure for electron microscopy in seconds. J Histochem Cytochem. 1990 Jun; 38(6):755-62.
Rapid primary microwave-osmium fixation. I. Preservation of structure for electron microscopy in seconds.
Microwave fixation provides excellent preservation of tissue, cells and antigens for light and electron microscopy. Histochem J. 1988 Jun-Jul; 20(6-7):373-87.
Microwave fixation provides excellent preservation of tissue, cells and antigens for light and electron microscopy.
Weller PF, Ackerman SJ, Nicholson-Weller A, Dvorak AM
Cytoplasmic lipid bodies of human neutrophilic leukocytes. Am J Pathol. 1989 Nov; 135(5):947-59.
Cytoplasmic lipid bodies of human neutrophilic leukocytes.
Zukauskas A, Merley A, Li D, Ang LH, Sciuto TE, Salman S, Dvorak AM, Dvorak HF, Jaminet SC
TM4SF1: a tetraspanin-like protein necessary for nanopodia formation and endothelial cell migration. Angiogenesis. 2011 Sep; 14(3):345-54.
TM4SF1: a tetraspanin-like protein necessary for nanopodia formation and endothelial cell migration.
Login GR, Galli SJ, Morgan E, Arizono N, Schwartz LB, Dvorak AM
Rapid microwave fixation of rat mast cells. I. Localization of granule chymase with an ultrastructural postembedding immunogold technique. Lab Invest. 1987 Nov; 57(5):592-9.
Rapid microwave fixation of rat mast cells. I. Localization of granule chymase with an ultrastructural postembedding immunogold technique.
Dvorak HF, Nagy JA, Berse B, Brown LF, Yeo KT, Yeo TK, Dvorak AM, van de Water L, Sioussat TM, Senger DR
Annals of the New York Academy of Sciences
Vascular permeability factor, fibrin, and the pathogenesis of tumor stroma formation. Ann N Y Acad Sci. 1992 Dec 04; 667:101-11.
Vascular permeability factor, fibrin, and the pathogenesis of tumor stroma formation.
Ultrastructural immunogold localization of osteopontin in human gastric mucosa. J Histochem Cytochem. 1997 Jan; 45(1):21-33.
Ultrastructural immunogold localization of osteopontin in human gastric mucosa.
Nagy JA, Eckelhoefer IA, Masse EM, Dvorak AM, Dvorak HF
European journal of cancer (Oxford, England : 1990)
Vascular targeting of solid and ascites tumours with antibodies to vascular endothelial growth factor. Eur J Cancer. 1996 Dec; 32A(14):2467-73.
Vascular targeting of solid and ascites tumours with antibodies to vascular endothelial growth factor.
Bozza PT, Yu W, Penrose JF, Morgan ES, Dvorak AM, Weller PF
Eosinophil lipid bodies: specific, inducible intracellular sites for enhanced eicosanoid formation. J Exp Med. 1997 Sep 15; 186(6):909-20.
Eosinophil lipid bodies: specific, inducible intracellular sites for enhanced eicosanoid formation.
Login GR, Aoki M, Yamakawa M, Lunardi LO, Digenis EC, Tanda N, Schwartz LB, Dvorak AM
Immunocytochemical localization of chymase to cytoplasmic vesicles after rat peritoneal mast cell stimulation by compound 48/80. J Histochem Cytochem. 1997 Oct; 45(10):1379-91.
Immunocytochemical localization of chymase to cytoplasmic vesicles after rat peritoneal mast cell stimulation by compound 48/80.
Dvorak AM, Letourneau L, Weller PF, Ackerman SJ
Ultrastructural localization of Charcot-Leyden crystal protein (lysophospholipase) to intracytoplasmic crystals in tumor cells of primary solid and papillary epithelial neoplasm of the pancreas. Lab Invest. 1990 May; 62(5):608-15.
Ultrastructural localization of Charcot-Leyden crystal protein (lysophospholipase) to intracytoplasmic crystals in tumor cells of primary solid and papillary epithelial neoplasm of the pancreas.
Dvorak AM, Miura T, Letourneau L, Ishizaka T, Kawakami T
Spontaneous degranulation of cultured bone-marrow-derived immature mast cells from X-linked immunodeficient (Xid) mice. Int Arch Allergy Immunol. 1996 Oct; 111(2):118-25.
Spontaneous degranulation of cultured bone-marrow-derived immature mast cells from X-linked immunodeficient (Xid) mice.
Weller PF, Lim K, Wan HC, Dvorak AM, Wong DT, Cruikshank WW, Kornfeld H, Center DM
The European respiratory journal. Supplement
Role of the eosinophil in allergic reactions. Eur Respir J Suppl. 1996 Aug; 22:109s-115s.
Role of the eosinophil in allergic reactions.
Harris NL, Dvorak AM, Smith J, Dvorak HF
Fibrin deposits in Hodgkin's disease. Am J Pathol. 1982 Jul; 108(1):119-29.
Dvorak AM, Nabel G, Pyne K, Cantor H, Dvorak HF, Galli SJ
Ultrastructural identification of the mouse basophil. Blood. 1982 Jun; 59(6):1279-85.
Ultrastructural identification of the mouse basophil.
Dvorak AM, Ishizaka T, Letourneau L, Albee EA, Mitsui H, Ackerman SJ
Charcot-Leyden crystal protein distribution in basophils and its absence in mast cells that differentiate from human umbilical cord blood precursor cells cultured in murine fibroblast culture supernatants or in recombinant human c-kit ligand. J Histochem Cytochem. 1994 Feb; 42(2):251-63.
Charcot-Leyden crystal protein distribution in basophils and its absence in mast cells that differentiate from human umbilical cord blood precursor cells cultured in murine fibroblast culture supernatants or in recombinant human c-kit ligand.
Dvorak AM, Seder RA, Paul WE, Morgan ES, Galli SJ
Effects of interleukin-3 with or without the c-kit ligand, stem cell factor, on the survival and cytoplasmic granule formation of mouse basophils and mast cells in vitro. Am J Pathol. 1994 Jan; 144(1):160-70.
Effects of interleukin-3 with or without the c-kit ligand, stem cell factor, on the survival and cytoplasmic granule formation of mouse basophils and mast cells in vitro.
Human and murine recombinant c-kit ligands support the development of human mast cells from umbilical cord blood cells: ultrastructural identification. Int Arch Allergy Immunol. 1993; 101(3):247-53.
Human and murine recombinant c-kit ligands support the development of human mast cells from umbilical cord blood cells: ultrastructural identification.
Stimulation of partial development of human mast cells by supernatant fluid from mouse fibroblast cultures. Clin Exp Allergy. 1994 Jul; 24(7):649-59.
Stimulation of partial development of human mast cells by supernatant fluid from mouse fibroblast cultures.
Nagy JA, Vasile E, Feng D, Sundberg C, Brown LF, Detmar MJ, Lawitts JA, Benjamin L, Tan X, Manseau EJ, Dvorak AM, Dvorak HF
Vascular permeability factor/vascular endothelial growth factor induces lymphangiogenesis as well as angiogenesis. J Exp Med. 2002 Dec 02; 196(11):1497-506.
Vascular permeability factor/vascular endothelial growth factor induces lymphangiogenesis as well as angiogenesis.
Neuroendocrine cell secretory granules are not bacteria in inflammatory bowel disease. Gastroenterology. 2003 Oct; 125(4):1288.
Neuroendocrine cell secretory granules are not bacteria in inflammatory bowel disease.
Immunogold ultrastructural techniques identify subcellular sites of chymase, Charcot-Leyden crystal protein, and histamine in basophils and mast cells. Chem Immunol Allergy. 2005; 85:89-97.
Immunogold ultrastructural techniques identify subcellular sites of chymase, Charcot-Leyden crystal protein, and histamine in basophils and mast cells.
Piecemeal degranulation of basophils and mast cells is effected by vesicular transport of stored secretory granule contents. Chem Immunol Allergy. 2005; 85:135-84.
Piecemeal degranulation of basophils and mast cells is effected by vesicular transport of stored secretory granule contents.
Beil WJ, Login GR, Aoki M, Lunardi LO, Morgan ES, Galli SJ, Dvorak AM
Tumor necrosis factor alpha immunoreactivity of rat peritoneal mast cell granules decreases during early secretion induced by compound 48/80: an ultrastructural immunogold morphometric analysis. Int Arch Allergy Immunol. 1996 Apr; 109(4):383-9.
Tumor necrosis factor alpha immunoreactivity of rat peritoneal mast cell granules decreases during early secretion induced by compound 48/80: an ultrastructural immunogold morphometric analysis.
Galli SJ, Brooks CG, Dvorak AM, Ishizaka T
Lack of detectable immunoglobulin E receptor expression on 33 of 34 cell lines with natural killer-like or cytotoxic-T-lymphocyte activity. Cell Immunol. 1985 Nov; 96(1):223-30.
Lack of detectable immunoglobulin E receptor expression on 33 of 34 cell lines with natural killer-like or cytotoxic-T-lymphocyte activity.
Lanir N, Ciano PS, Van de Water L, McDonagh J, Dvorak AM, Dvorak HF
Macrophage migration in fibrin gel matrices. II. Effects of clotting factor XIII, fibronectin, and glycosaminoglycan content on cell migration. J Immunol. 1988 Apr 01; 140(7):2340-9.
Macrophage migration in fibrin gel matrices. II. Effects of clotting factor XIII, fibronectin, and glycosaminoglycan content on cell migration.
Microwave energy fixation for electron microscopy. Am J Pathol. 1985 Aug; 120(2):230-43.
Microwave energy fixation for electron microscopy.
Ciano PS, Colvin RB, Dvorak AM, McDonagh J, Dvorak HF
Macrophage migration in fibrin gel matrices. Lab Invest. 1986 Jan; 54(1):62-70.
Macrophage migration in fibrin gel matrices.
Hammond ME, Roblin RO, Dvorak AM, Selvaggio SS, Black PH, Dvorak HF
MIF-like activity in simian virus 40-transformed 3T3 fibroblast cultures. Science. 1974 Sep 13; 185(4155):955-7.
MIF-like activity in simian virus 40-transformed 3T3 fibroblast cultures.
Orenstein NS, Galli SJ, Dvorak AM, Silbert JE, Dvorak HF
Sulfated glycosaminoglycans of guinea pig basophilic leukocytes. J Immunol. 1978 Aug; 121(2):586-92.
Sulfated glycosaminoglycans of guinea pig basophilic leukocytes.
Dvorak AM, Osage JE, Dvorak HF, Galli SJ
Surface membrane alterations in guinea pig basophils undergoing anaphylactic degranulation. A scanning electron microscopic study. Lab Invest. 1981 Jul; 45(1):58-66.
Surface membrane alterations in guinea pig basophils undergoing anaphylactic degranulation. A scanning electron microscopic study.
Dvorak AM, Seder RA, Paul WE, Kissell-Rainville S, Plaut M, Galli SJ
Ultrastructural characteristics of Fc epsilon R-positive basophils in the spleen and bone marrow of mice immunized with goat anti-mouse IgD antibody. Lab Invest. 1993 Jun; 68(6):708-15.
Ultrastructural characteristics of Fc epsilon R-positive basophils in the spleen and bone marrow of mice immunized with goat anti-mouse IgD antibody.
Isomura T, Dvorak AM, Garcia RI, Dvorak HF, Galli SJ
Inbred guinea pig aortic endothelial cell clones. Model for studying the vascular endothelium under totally isologous conditions. Lab Invest. 1986 Dec; 55(6):703-16.
Inbred guinea pig aortic endothelial cell clones. Model for studying the vascular endothelium under totally isologous conditions.
Dvorak HF, Nagy JA, Dvorak JT, Dvorak AM
Identification and characterization of the blood vessels of solid tumors that are leaky to circulating macromolecules. Am J Pathol. 1988 Oct; 133(1):95-109.
Identification and characterization of the blood vessels of solid tumors that are leaky to circulating macromolecules.
Burd PR, Rogers HW, Gordon JR, Martin CA, Jayaraman S, Wilson SD, Dvorak AM, Galli SJ, Dorf ME
Interleukin 3-dependent and -independent mast cells stimulated with IgE and antigen express multiple cytokines. J Exp Med. 1989 Jul 01; 170(1):245-57.
Interleukin 3-dependent and -independent mast cells stimulated with IgE and antigen express multiple cytokines.
Dvorak AM, Monahan-Earley RA, Estrella P, Kissell S, Donahue RE
Ultrastructure of monkey peripheral blood basophils stimulated to develop in vivo by recombinant human interleukin 3. Lab Invest. 1989 Dec; 61(6):677-90.
Ultrastructure of monkey peripheral blood basophils stimulated to develop in vivo by recombinant human interleukin 3.
Dvorak AM, Saito H, Estrella P, Kissell S, Arai N, Ishizaka T
Ultrastructure of eosinophils and basophils stimulated to develop in human cord blood mononuclear cell cultures containing recombinant human interleukin-5 or interleukin-3. Lab Invest. 1989 Jul; 61(1):116-32.
Ultrastructure of eosinophils and basophils stimulated to develop in human cord blood mononuclear cell cultures containing recombinant human interleukin-5 or interleukin-3.
Fox CC, Dvorak AM, Peters SP, Kagey-Sobotka A, Lichtenstein LM
Isolation and characterization of human intestinal mucosal mast cells. J Immunol. 1985 Jul; 135(1):483-91.
Isolation and characterization of human intestinal mucosal mast cells.
Dvorak HF, Selvaggio SS, Dvorak AM, Colvin RB, Lean DB, Rypysc J
Purification of basophilic leukocytes from guinea pig blood and bone marrow. J Immunol. 1974 Dec; 113(6):1694-702.
Purification of basophilic leukocytes from guinea pig blood and bone marrow.
Uptake of horseradish peroxidase by guinea pig basophilic leukocytes. Lab Invest. 1972 Jan; 26(1):27-39.
Uptake of horseradish peroxidase by guinea pig basophilic leukocytes.
Dvorak HF, Dickersin GR, Dvorak AM, Manseau EJ, Pyne K
Human breast carcinoma: fibrin deposits and desmoplasia. Inflammatory cell type and distribution. Microvasculature and infarction. J Natl Cancer Inst. 1981 Aug; 67(2):335-45.
Human breast carcinoma: fibrin deposits and desmoplasia. Inflammatory cell type and distribution. Microvasculature and infarction.
Dvorak HF, Orenstein NS, Carvalho AC, Churchill WH, Dvorak AM, Galli SJ, Feder J, Bitzer AM, Rypysc J, Giovinco P
Induction of a fibrin-gel investment: an early event in line 10 hepatocarcinoma growth mediated by tumor-secreted products. J Immunol. 1979 Jan; 122(1):166-74.
Induction of a fibrin-gel investment: an early event in line 10 hepatocarcinoma growth mediated by tumor-secreted products.
Crohn's disease--mast cell quantitation using one micron plastic sections for light microscopic study. Pathol Annu. 1983; 18 Pt 1:181-90.
Crohn's disease--mast cell quantitation using one micron plastic sections for light microscopic study.
Similarities in the ultrastructural morphology and developmental and secretory mechanisms of human basophils and eosinophils. J Allergy Clin Immunol. 1994 Dec; 94(6 Pt 2):1103-34.
Similarities in the ultrastructural morphology and developmental and secretory mechanisms of human basophils and eosinophils.
Brown LF, Senger DR, Geng LL, Dvorak HF, Dvorak AM
Ultrastructural immunogold localization of osteopontin in human gallbladder epithelial cells. J Histochem Cytochem. 1994 Mar; 42(3):351-61.
Ultrastructural immunogold localization of osteopontin in human gallbladder epithelial cells.
Brown LF, Lanir N, McDonagh J, Tognazzi K, Dvorak AM, Dvorak HF
Fibroblast migration in fibrin gel matrices. Am J Pathol. 1993 Jan; 142(1):273-83.
Fibroblast migration in fibrin gel matrices.
Hoeppner LH, Phoenix KN, Clark KJ, Bhattacharya R, Gong X, Sciuto TE, Vohra P, Suresh S, Bhattacharya S, Dvorak AM, Ekker SC, Dvorak HF, Claffey KP, Mukhopadhyay D
Revealing the role of phospholipase Cß3 in the regulation of VEGF-induced vascular permeability. Blood. 2012 Sep 13; 120(11):2167-73.
Revealing the role of phospholipase Cß3 in the regulation of VEGF-induced vascular permeability.
Tortella BJ, Matthews JB, Antonioli DA, Dvorak AM, Silen W
Gastric autonomic nerve (GAN) tumor and extra-adrenal paraganglioma in Carney's triad. A common origin. Ann Surg. 1987 Mar; 205(3):221-5.
Gastric autonomic nerve (GAN) tumor and extra-adrenal paraganglioma in Carney's triad. A common origin.
Guinea pig bone marrow basophilopoiesis. J Exp Pathol. 1985; 2(1):13-24.
Guinea pig bone marrow basophilopoiesis.
Mast cells in the cortical tubular epithelium and interstitium in human renal disease. Hum Pathol. 1974 May; 5(3):315-26.
Mast cells in the cortical tubular epithelium and interstitium in human renal disease.
Dvorak HF, Orenstein NS, Rypysc J, Colvin RB, Dvorak AM
Plasminogen activator of guinea pig basophilic leukocytes: probable localization to the plasma membrane. J Immunol. 1978 Mar; 120(3):766-73.
Plasminogen activator of guinea pig basophilic leukocytes: probable localization to the plasma membrane.
Fibrin as a component of the tumor stroma: origins and biological significance. Cancer Metastasis Rev. 1983; 2(1):41-73.
Fibrin as a component of the tumor stroma: origins and biological significance.
Senger DR, Galli SJ, Dvorak AM, Perruzzi CA, Harvey VS, Dvorak HF
Tumor cells secrete a vascular permeability factor that promotes accumulation of ascites fluid. Science. 1983 Feb 25; 219(4587):983-5.
Tumor cells secrete a vascular permeability factor that promotes accumulation of ascites fluid.
Orenstein NS, Galli SJ, Dvorak AM, Dvorak HF
Glycosaminoglycans and proteases of guinea pig basophilic leukocytes. Kroc Found Ser. 1981; 14:123-43.
Glycosaminoglycans and proteases of guinea pig basophilic leukocytes.
Dvoràk AM, Morgan ES, Tzizik DM, Weller PF
Prostaglandin endoperoxide synthase (cyclooxygenase): ultrastructural localization to nonmembrane-bound cytoplasmic lipid bodies in human eosinophils and 3T3 fibroblasts. Int Arch Allergy Immunol. 1994 Nov; 105(3):245-50.
Prostaglandin endoperoxide synthase (cyclooxygenase): ultrastructural localization to nonmembrane-bound cytoplasmic lipid bodies in human eosinophils and 3T3 fibroblasts.
Kopicky-Burd JA, Kagey-Sobotka A, Peters SP, Dvorak AM, Lennox DW, Lichtenstein LM, Wigley FM
Characterization of human synovial mast cells. J Rheumatol. 1988 Sep; 15(9):1326-33.
Characterization of human synovial mast cells.
Chang SH, Feng D, Nagy JA, Sciuto TE, Dvorak AM, Dvorak HF
Vascular permeability and pathological angiogenesis in caveolin-1-null mice. Am J Pathol. 2009 Oct; 175(4):1768-76.
Vascular permeability and pathological angiogenesis in caveolin-1-null mice.
Ishizaka T, Saito H, Hatake K, Dvorak AM, Leiferman KM, Arai N, Ishizaka K
Preferential differentiation of inflammatory cells by recombinant human interleukins. Int Arch Allergy Appl Immunol. 1989; 88(1-2):46-9.
Preferential differentiation of inflammatory cells by recombinant human interleukins.
Localization of Charcot-Leyden crystal protein in individual morphological phenotypes of human basophils stimulated by f-Met peptide. Clin Exp Allergy. 1997 Apr; 27(4):452-74.
Localization of Charcot-Leyden crystal protein in individual morphological phenotypes of human basophils stimulated by f-Met peptide.
Ribonuclease-gold labels heparin in human mast cell granules. New use for an ultrastructural enzyme affinity technique. J Histochem Cytochem. 1998 Jun; 46(6):695-706.
Ribonuclease-gold labels heparin in human mast cell granules. New use for an ultrastructural enzyme affinity technique.
Cytoplasmic lipid bodies in eosinophils: central roles in eicosanoid generation. Int Arch Allergy Immunol. 1999 Feb-Apr; 118(2-4):450-2.
Cytoplasmic lipid bodies in eosinophils: central roles in eicosanoid generation.
Ultrastructural analysis of human eosinophils. Chem Immunol. 2000; 76:1-28.
Ultrastructural analysis of human eosinophils.
Pantanowitz L, Aufranc S, Monahan-Earley R, Dvorak A, Telford SR
Transfusion medicine illustrated. Morphologic hallmarks of Babesia. Transfusion. 2002 Nov; 42(11):1389.
Transfusion medicine illustrated. Morphologic hallmarks of Babesia.
Feyerabend TB, Hausser H, Tietz A, Blum C, Hellman L, Straus AH, Takahashi HK, Morgan ES, Dvorak AM, Fehling HJ, Rodewald HR
Loss of histochemical identity in mast cells lacking carboxypeptidase A. Mol Cell Biol. 2005 Jul; 25(14):6199-210.
Loss of histochemical identity in mast cells lacking carboxypeptidase A.
Granule changes of human skin mast cells characteristic of piecemeal degranulation and associated with recovery during wound healing in situ. J Leukoc Biol. 1991 Feb; 49(2):197-210.
Granule changes of human skin mast cells characteristic of piecemeal degranulation and associated with recovery during wound healing in situ.
Phung TL, Ziv K, Dabydeen D, Eyiah-Mensah G, Riveros M, Perruzzi C, Sun J, Monahan-Earley RA, Shiojima I, Nagy JA, Lin MI, Walsh K, Dvorak AM, Briscoe DM, Neeman M, Sessa WC, Dvorak HF, Benjamin LE
Pathological angiogenesis is induced by sustained Akt signaling and inhibited by rapamycin. Cancer Cell. 2006 Aug; 10(2):159-70.
Pathological angiogenesis is induced by sustained Akt signaling and inhibited by rapamycin.
Neutrophils emigrate from venules by a transendothelial cell pathway in response to FMLP. J Exp Med. 1998 Mar 16; 187(6):903-15.
Neutrophils emigrate from venules by a transendothelial cell pathway in response to FMLP.
Arachidonic acid incorporation by cytoplasmic lipid bodies of human eosinophils. Blood. 1985 May; 65(5):1269-74.
Arachidonic acid incorporation by cytoplasmic lipid bodies of human eosinophils.
Galli SJ, Dvorak AM, Ishizaka T, Nabel G, Der Simonian H, Cantor H, Dvorak HF
A cloned cell with NK function resembles basophils by ultrastructure and expresses IgE receptors. Nature. 1982 Jul 15; 298(5871):288-90.
A cloned cell with NK function resembles basophils by ultrastructure and expresses IgE receptors.
VEGF-A(164/165) and PlGF: roles in angiogenesis and arteriogenesis. Trends Cardiovasc Med. 2003 Jul; 13(5):169-75.
VEGF-A(164/165) and PlGF: roles in angiogenesis and arteriogenesis.
Weller PF, Marshall WL, Lucey DR, Rand TH, Dvorak AM, Finberg RW
Infection, apoptosis, and killing of mature human eosinophils by human immunodeficiency virus-1. Am J Respir Cell Mol Biol. 1995 Nov; 13(5):610-20.
Infection, apoptosis, and killing of mature human eosinophils by human immunodeficiency virus-1.