Elion, Elaine
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The MAPKKK Ste11 regulates vegetative growth through a kinase cascade of shared signaling components.
PubMed Identifier: 10535982
author list: Lee BN, Elion EA
published in: Proceedings of the National Academy of Sciences of the United States of America
information resource reference: The MAPKKK Ste11 regulates vegetative growth through a kinase cascade of shared signaling components. Proc Natl Acad Sci U S A. 1999 Oct 26; 96(22):12679-84.
journal title abbreviation: Proc Natl Acad Sci U S A
publication date: 1999-10-26T00:00:00
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FUS3 encodes a cdc2+/CDC28-related kinase required for the transition from mitosis into conjugation.
PubMed Identifier: 2406028
author list: Elion EA, Grisafi PL, Fink GR
published in: Cell
information resource reference: FUS3 encodes a cdc2+/CDC28-related kinase required for the transition from mitosis into conjugation. Cell. 1990 Feb 23; 60(4):649-64.
journal title abbreviation: Cell
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Ste5 tethers multiple protein kinases in the MAP kinase cascade required for mating in S. cerevisiae.
PubMed Identifier: 8062390
author list: Choi KY, Satterberg B, Lyons DM, Elion EA
published in: Cell
information resource reference: Ste5 tethers multiple protein kinases in the MAP kinase cascade required for mating in S. cerevisiae. Cell. 1994 Aug 12; 78(3):499-512.
journal title abbreviation: Cell
publication date: 1994-08-12T00:00:00
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Localized feedback phosphorylation of Ste5p scaffold by associated MAPK cascade.
PubMed Identifier: 15322134
author list: Flotho A, Simpson DM, Qi M, Elion EA
published in: The Journal of biological chemistry
information resource reference: Localized feedback phosphorylation of Ste5p scaffold by associated MAPK cascade. J Biol Chem. 2004 Nov 05; 279(45):47391-401.
journal title abbreviation: J Biol Chem
publication date: 2004-08-20T00:00:00
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Detection of protein-protein interactions by coprecipitation.
PubMed Identifier: 18432998
author list: Elion EA
published in: Current protocols in immunology
information resource reference: Detection of protein-protein interactions by coprecipitation. Curr Protoc Immunol. 2007 Feb; Chapter 8:8.7.1-8.7.10.
journal title abbreviation: Curr Protoc Immunol
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A role for autophosphorylation revealed by activated alleles of FUS3, the yeast MAP kinase homolog.
PubMed Identifier: 8049522
author list: Brill JA, Elion EA, Fink GR
published in: Molecular biology of the cell
information resource reference: A role for autophosphorylation revealed by activated alleles of FUS3, the yeast MAP kinase homolog. Mol Biol Cell. 1994 Mar; 5(3):297-312.
journal title abbreviation: Mol Biol Cell
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Functional binding between Gbeta and the LIM domain of Ste5 is required to activate the MEKK Ste11.
PubMed Identifier: 9501067
author list: Feng Y, Song LY, Kincaid E, Mahanty SK, Elion EA
published in: Current biology : CB
information resource reference: Functional binding between Gbeta and the LIM domain of Ste5 is required to activate the MEKK Ste11. Curr Biol. 1998 Feb 26; 8(5):267-78.
journal title abbreviation: Curr Biol
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far4, far5, and far6 define three genes required for efficient activation of MAPKs Fus3 and Kss1 and accumulation of glycogen.
PubMed Identifier: 11570512
author list: Cherkasova V, Elion EA
published in: Current genetics
information resource reference: far4, far5, and far6 define three genes required for efficient activation of MAPKs Fus3 and Kss1 and accumulation of glycogen. Curr Genet. 2001 Aug; 40(1):13-26.
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Fus2 localizes near the site of cell fusion and is required for both cell fusion and nuclear alignment during zygote formation.
PubMed Identifier: 7559752
author list: Elion EA, Trueheart J, Fink GR
published in: The Journal of cell biology
information resource reference: Fus2 localizes near the site of cell fusion and is required for both cell fusion and nuclear alignment during zygote formation. J Cell Biol. 1995 Sep; 130(6):1283-96.
journal title abbreviation: J Cell Biol
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type: Academic Article
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Signal transduction. Signaling specificity in yeast.
PubMed Identifier: 15692041
author list: Elion EA, Qi M, Chen W
published in: Science (New York, N.Y.)
information resource reference: Signal transduction. Signaling specificity in yeast. Science. 2005 Feb 04; 307(5710):687-8.
journal title abbreviation: Science
publication date: 2005-02-04T00:00:00
year: 2005
type: Academic Article
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Ste11p MEKK signals through HOG, mating, calcineurin and PKC pathways to regulate the FKS2 gene.
PubMed Identifier: 22114773
author list: Wang X, Sheff MA, Simpson DM, Elion EA
published in: BMC molecular biology
information resource reference: Ste11p MEKK signals through HOG, mating, calcineurin and PKC pathways to regulate the FKS2 gene. BMC Mol Biol. 2011 Nov 24; 12:51.
journal title abbreviation: BMC Mol Biol
publication date: 2011-11-24T00:00:00
year: 2011
type: Academic Article
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An RNA polymerase I enhancer in Saccharomyces cerevisiae.
PubMed Identifier: 3537713
author list: Elion EA, Warner JR
published in: Molecular and cellular biology
information resource reference: An RNA polymerase I enhancer in Saccharomyces cerevisiae. Mol Cell Biol. 1986 Jun; 6(6):2089-97.
journal title abbreviation: Mol Cell Biol
publication date: 1986-06-01T00:00:00
year: 1986
type: Academic Article
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Fungal Proteins
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Saccharomyces cerevisiae Proteins
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Lassar, Andrew
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Dubreuil, Catherine
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Gygi, Steven
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Richardson, U.
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Winston, Fred
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Moqtaderi, Zarmik
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linked information resource: Nuclear export and plasma membrane recruitment of the Ste5 scaffold are coordinated with oligomerization and association with signal transduction components.

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linked information resource: How to monitor nuclear shuttling.

Authorship 184058
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linked information resource: A role for autophosphorylation revealed by activated alleles of FUS3, the yeast MAP kinase homolog.

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linked information resource: The MAP kinase Fus3 associates with and phosphorylates the upstream signaling component Ste5.

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linked information resource: POG1, a novel yeast gene, promotes recovery from pheromone arrest via the G1 cyclin CLN2.

Authorship 343713
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linked information resource: Constructing recombinant DNA molecules by PCR.

Hamilton Kuhn Professor of Biological Chemistry and Molecular Pharmacology
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Manandhar, Monica
eCommons Login: MM119
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linked information resource: Effects of HSP70 chaperones Ssa1 and Ssa2 on Ste5 scaffold and the mating mitogen-activated protein kinase (MAPK) pathway in Saccharomyces cerevisiae.

Effects of HSP70 chaperones Ssa1 and Ssa2 on Ste5 scaffold and the mating mitogen-activated protein kinase (MAPK) pathway in Saccharomyces cerevisiae.
PubMed Identifier: 37851593
author list: Farley FW, McCully RR, Maslo PB, Yu L, Sheff MA, Sadeghi H, Elion EA
published in: PloS one
information resource reference: Effects of HSP70 chaperones Ssa1 and Ssa2 on Ste5 scaffold and the mating mitogen-activated protein kinase (MAPK) pathway in Saccharomyces cerevisiae. PLoS One. 2023; 18(10):e0289339.
journal title abbreviation: PLoS One
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year: 2023
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linked information resource: Routing MAP kinase cascades.

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linked information resource: Differential input by Ste5 scaffold and Msg5 phosphatase route a MAPK cascade to multiple outcomes.

David Wesley Gaiser Professor of Biological Chemistry and Molecular Pharmacology
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linked information resource: The Ste5p scaffold.

Authorship 368613
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linked information resource: The osmoregulatory pathway represses mating pathway activity in Saccharomyces cerevisiae: isolation of a FUS3 mutant that is insensitive to the repression mechanism.

Don W. Fawcett Professor of Cell Biology
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Authorship 33162
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linked information resource: Counteractive control of polarized morphogenesis during mating by mitogen-activated protein kinase Fus3 and G1 cyclin-dependent kinase.

Authorship 244060
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linked information resource: Formin-induced actin cables are required for polarized recruitment of the Ste5 scaffold and high level activation of MAPK Fus3.

Professor of Biological Chemistry and Molecular Pharmacology
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linked information resource: Ste5 tethers multiple protein kinases in the MAP kinase cascade required for mating in S. cerevisiae.

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linked information resource: An RNA polymerase I enhancer in Saccharomyces cerevisiae.

Authorship 467006
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linked information resource: FUS3 encodes a cdc2+/CDC28-related kinase required for the transition from mitosis into conjugation.

Authorship 541395
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linked information resource: Pheromone response, mating and cell biology.

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author rank in publication: 2
linked author: Elion, Elaine
linked information resource: Thiobarbituric acid reactive material in uremic blood.

Authorship 781777
type: Authorship
linked author: Elion, Elaine
linked information resource: The ribosomal genes of yeast and their regulation

Authorship 781778
type: Authorship
linked author: Elion, Elaine
linked information resource: FUS3. In: Protein Kinase Factsbook, Hanks S and Hardie DG, editors, Academic Press

Authorship 781779
type: Authorship
linked author: Elion, Elaine
linked information resource: https://connects.catalyst.harvard.edu/Profiles/profile/39075642

Authorship 781780
type: Authorship
linked author: Elion, Elaine
linked information resource: Co-precipitating proteins. Current Protocols in Molecular Biology, Ausubel,F, Brent R Kingston R, Moore D, Smith JA, Seidman J, Struhl K, editors.. Guilford, CT: Greene Publishing Associates and Wiley

Authorship 781781
type: Authorship
linked author: Elion, Elaine
linked information resource: MAP Kinase Modules in Signaling; Encyclopedia of Cancer, Second Edition I. Biology of Cancer, Wang J, editor. San Diego, California: Academic Press

Authorship 781782
type: Authorship
linked author: Elion, Elaine
linked information resource: MAP kinase in yeast. Handbook of Cellular Signaling, Bradshaw R. and Dennis E, editors, T. Hunter T and Scott JD, associate editors. Academic Press

Authorship 781783
type: Authorship
linked author: Elion, Elaine
linked information resource: Co-precipitating proteins. For: Signal Transduction Protocols in Methods in Molecular Biology, R.C. Dickson RC and Mendenhall MD, editors. Human Press

Authorship 781784
type: Authorship
linked author: Elion, Elaine
linked information resource: Making protein immunoprecipitates. Methods in Molecular Biology 2004; 284: 1-14

Authorship 781785
type: Authorship
linked author: Elion, Elaine
linked information resource: MAP kinase in yeast. Handbook of Cellular Signaling, Bradshaw R. and Dennis E, editors, T. Hunter T and Scott JD, associate editors. Academic Press

Authorship 781786
type: Authorship
linked author: Elion, Elaine
linked information resource: https://connects.catalyst.harvard.edu/Profiles/profile/39075627

Authorship 781787
type: Authorship
linked author: Elion, Elaine
linked information resource: Sequence Specificty in Transcription and Translation, UCLA Symposia on Molecular and Cellular Biology, New Series, Calendar R and Gold L, editors

Authorship 781788
type: Authorship
linked author: Elion, Elaine
linked information resource: https://connects.catalyst.harvard.edu/Profiles/profile/39075615

Authorship 781789
type: Authorship
linked author: Elion, Elaine
linked information resource: A novel functional link between MAPKs and the Ras/cAMP pathway required for survival

Making protein immunoprecipitates. Methods in Molecular Biology 2004; 284: 1-14
author list: Elion EA and Wang YM
published in: Making protein immunoprecipitates. Methods in Molecular Biology 2004; 284: 1-14
information resource reference: Making protein immunoprecipitates. Methods in Molecular Biology 2004; 284: 1-14.
publication date: 1900-01-01T00:00:00
year: 1900
type: Academic Article
type: Article
type: Document
type: Information Resource

Co-precipitating proteins. Current Protocols in Molecular Biology, Ausubel,F, Brent R Kingston R, Moore D, Smith JA, Seidman J, Struhl K, editors.. Guilford, CT: Greene Publishing Associates and Wiley
author list: Elion EA
published in: Co-precipitating proteins. Current Protocols in Molecular Biology, Ausubel,F, Brent R Kingston R, Moore D, Smith JA, Seidman J, Struhl K, editors.. Guilford, CT: Greene Publishing Associates and Wiley
information resource reference: Co-precipitating proteins. Current Protocols in Molecular Biology, Ausubel,F, Brent R Kingston R, Moore D, Smith JA, Seidman J, Struhl K, editors.. Guilford, CT: Greene Publishing Associates and Wiley. 2000.
publication date: 2000-01-01T00:00:00
year: 2000
type: Academic Article
type: Article
type: Document
type: Information Resource

https://connects.catalyst.harvard.edu/Profiles/profile/39075615
author list: Elion EA and Warner JR
published in: Characterization of a yeast RNA polymerase I enhancer. Transcriptional Control Mechanisms, UCLA Symposia on Molecular and Cellular Biology, New Series, Volume 52, Granner DK, Rosenfeld G and Chang S, editors
information resource reference: Characterization of a yeast RNA polymerase I enhancer. Transcriptional Control Mechanisms, UCLA Symposia on Molecular and Cellular Biology, New Series, Volume 52, Granner DK, Rosenfeld G and Chang S, editors. 1985.
publication date: 1985-01-01T00:00:00
year: 1985
type: Academic Article
type: Article
type: Document
type: Information Resource
label: Characterization of a yeast RNA polymerase I enhancer. Transcriptional Control Mechanisms, UCLA Symposia on Molecular and Cellular Biology, New Series, Volume 52, Granner DK, Rosenfeld G and Chang S, editors

Co-precipitating proteins. For: Signal Transduction Protocols in Methods in Molecular Biology, R.C. Dickson RC and Mendenhall MD, editors. Human Press
author list: Elion EA
published in: Co-precipitating proteins. For: Signal Transduction Protocols in Methods in Molecular Biology, R.C. Dickson RC and Mendenhall MD, editors. Human Press
information resource reference: Co-precipitating proteins. For: Signal Transduction Protocols in Methods in Molecular Biology, R.C. Dickson RC and Mendenhall MD, editors. Human Press. 2004.
publication date: 2004-01-01T00:00:00
year: 2004
type: Academic Article
type: Article
type: Document
type: Information Resource

The ribosomal genes of yeast and their regulation
author list: Warner J R, Elion E A, Dabeva M D, and Schwindinger WF
published in: Ribosomes: Genetics, Structure and Function
information resource reference: The ribosomal genes of yeast and their regulation. Ribosomes: Genetics, Structure and Function. 1988.
publication date: 1988-01-01T00:00:00
year: 1988
type: Academic Article
type: Article
type: Document
type: Information Resource

Thiobarbituric acid reactive material in uremic blood.
PubMed Identifier: 7329472
author list: Fillit H, Elion E, Sullivan J, Sherman R, Zabriskie JB
published in: Nephron
information resource reference: Thiobarbituric acid reactive material in uremic blood. Nephron. 1981; 29(1-2):40-3.
journal title abbreviation: Nephron
publication date: 1981-01-01T00:00:00
year: 1981
type: Academic Article
type: Article
type: Document
type: Information Resource

MAP kinase in yeast. Handbook of Cellular Signaling, Bradshaw R. and Dennis E, editors, T. Hunter T and Scott JD, associate editors. Academic Press
author list: Sahoo R, Husain A and Elion EA
published in: MAP kinase in yeast. Handbook of Cellular Signaling, Bradshaw R. and Dennis E, editors, T. Hunter T and Scott JD, associate editors. Academic Press
information resource reference: MAP kinase in yeast. Handbook of Cellular Signaling, Bradshaw R. and Dennis E, editors, T. Hunter T and Scott JD, associate editors. Academic Press. 2008.
publication date: 2008-01-01T00:00:00
year: 2008
type: Academic Article
type: Article
type: Document
type: Information Resource

https://connects.catalyst.harvard.edu/Profiles/profile/39075627
author list: Elion EA
published in: MAP Kinase Modules in Signaling, Biomedical Sciences - Cancer and Endocrine Diseases, in the section Pathobiology of Cancer and Neoplasia, pp1-30 Michael Caplan, editor. Elsevier, Inc., Waltham, MA in press
information resource reference: MAP Kinase Modules in Signaling, Biomedical Sciences - Cancer and Endocrine Diseases, in the section Pathobiology of Cancer and Neoplasia, pp1-30 Michael Caplan, editor. Elsevier, Inc., Waltham, MA in press. 2015.
publication date: 2015-01-01T00:00:00
year: 2015
type: Academic Article
type: Article
type: Document
type: Information Resource
label: MAP Kinase Modules in Signaling, Biomedical Sciences - Cancer and Endocrine Diseases, in the section Pathobiology of Cancer and Neoplasia, pp1-30 Michael Caplan, editor. Elsevier, Inc., Waltham, MA in press

MAP Kinase Modules in Signaling; Encyclopedia of Cancer, Second Edition I. Biology of Cancer, Wang J, editor. San Diego, California: Academic Press
author list: Elion EA
published in: MAP Kinase Modules in Signaling; Encyclopedia of Cancer, Second Edition I. Biology of Cancer, Wang J, editor. San Diego, California: Academic Press
information resource reference: MAP Kinase Modules in Signaling; Encyclopedia of Cancer, Second Edition I. Biology of Cancer, Wang J, editor. San Diego, California: Academic Press. 2002.
publication date: 2002-01-01T00:00:00
year: 2002
type: Academic Article
type: Article
type: Document
type: Information Resource

FUS3. In: Protein Kinase Factsbook, Hanks S and Hardie DG, editors, Academic Press
author list: Elion EA and Fink GR
published in: FUS3. In: Protein Kinase Factsbook, Hanks S and Hardie DG, editors, Academic Press
information resource reference: FUS3. In: Protein Kinase Factsbook, Hanks S and Hardie DG, editors, Academic Press. 1988.
publication date: 1988-01-01T00:00:00
year: 1988
type: Academic Article
type: Article
type: Document
type: Information Resource

MAP kinase in yeast. Handbook of Cellular Signaling, Bradshaw R. and Dennis E, editors, T. Hunter T and Scott JD, associate editors. Academic Press
author list: Elion EA
published in: MAP kinase in yeast. Handbook of Cellular Signaling, Bradshaw R. and Dennis E, editors, T. Hunter T and Scott JD, associate editors. Academic Press
information resource reference: MAP kinase in yeast. Handbook of Cellular Signaling, Bradshaw R. and Dennis E, editors, T. Hunter T and Scott JD, associate editors. Academic Press. 2003.
publication date: 2003-01-01T00:00:00
year: 2003
type: Academic Article
type: Article
type: Document
type: Information Resource

Sequence Specificty in Transcription and Translation, UCLA Symposia on Molecular and Cellular Biology, New Series, Calendar R and Gold L, editors
author list: Elion EA and Warner JR
published in: Functional elements of the yeast rRNA transcription uni
information resource reference: Sequence Specificty in Transcription and Translation, UCLA Symposia on Molecular and Cellular Biology, New Series, Calendar R and Gold L, editors. Functional elements of the yeast rRNA transcription uni. 1985; 30.
publication date: 1985-01-01T00:00:00
year: 1985
type: Academic Article
type: Article
type: Document
type: Information Resource

A novel functional link between MAPKs and the Ras/cAMP pathway required for survival
author list: Cherkasova V McCully R Wang Y Hinnebusch A and Elion EA.
published in: Current Biology
information resource reference: A novel functional link between MAPKs and the Ras/cAMP pathway required for survival. Current Biology. 2003; (13):1214-1219.
publication date: 2003-01-01T00:00:00
year: 2003
type: Academic Article
type: Article
type: Document
type: Information Resource

https://connects.catalyst.harvard.edu/Profiles/profile/39075642
author list: Elion EA
published in: . Using the polymerase chain reaction to construct recombinant DNA molecules (Unit 3.17) In: Current Protocols in Molecular Biology, Ausubel,F, Brent R Kingston R, Moore D, Smith JA, Seidman J, Struhl K, editors.. Guilford, CT: Greene Publishing Associates and Wiley
information resource reference: . Using the polymerase chain reaction to construct recombinant DNA molecules (Unit 3.17) In: Current Protocols in Molecular Biology, Ausubel,F, Brent R Kingston R, Moore D, Smith JA, Seidman J, Struhl K, editors.. Guilford, CT: Greene Publishing Associates and Wiley. 1995.
publication date: 1995-01-01T00:00:00
year: 1995
type: Academic Article
type: Article
type: Document
type: Information Resource
label: . Using the polymerase chain reaction to construct recombinant DNA molecules (Unit 3.17) In: Current Protocols in Molecular Biology, Ausubel,F, Brent R Kingston R, Moore D, Smith JA, Seidman J, Struhl K, editors.. Guilford, CT: Greene Publishing Associates and Wiley

Authorship 463572
type: Authorship
author rank in publication: 4
linked author: Elion, Elaine
linked information resource: Cdc24 regulates nuclear shuttling and recruitment of the Ste5 scaffold to a heterotrimeric G protein in Saccharomyces cerevisiae.

Authorship 529865
type: Authorship
author rank in publication: 4
linked author: Elion, Elaine
linked information resource: Ste11p MEKK signals through HOG, mating, calcineurin and PKC pathways to regulate the FKS2 gene.

Authorship 417252
type: Authorship
author rank in publication: 1
linked author: Elion, Elaine
linked information resource: Detection of protein-protein interactions by coprecipitation.

Authorship 430558
type: Authorship
author rank in publication: 1
linked author: Elion, Elaine
linked information resource: Signal transduction. Signaling specificity in yeast.

Authorship 86924
type: Authorship
author rank in publication: 4
linked author: Elion, Elaine
linked information resource: Nuclear shuttling of yeast scaffold Ste5 is required for its recruitment to the plasma membrane and activation of the mating MAPK cascade.

Authorship 84401
type: Authorship
author rank in publication: 1
linked author: Elion, Elaine
linked information resource: Detection of protein-protein interactions by coprecipitation.

Authorship 296313
type: Authorship
author rank in publication: 1
linked author: Elion, Elaine
linked information resource: Methods for analyzing MAPK cascades.

Authorship 238288
type: Authorship
author rank in publication: 3
linked author: Elion, Elaine
linked information resource: Fus3p and Kss1p control G1 arrest in Saccharomyces cerevisiae through a balance of distinct arrest and proliferative functions that operate in parallel with Far1p.

Authorship 301029
type: Authorship
author rank in publication: 2
linked author: Elion, Elaine
linked information resource: far4, far5, and far6 define three genes required for efficient activation of MAPKs Fus3 and Kss1 and accumulation of glycogen.

Authorship 36788
type: Authorship
author rank in publication: 5
linked author: Elion, Elaine
linked information resource: The SH3-domain protein Bem1 coordinates mitogen-activated protein kinase cascade activation with cell cycle control in Saccharomyces cerevisiae.

Authorship 467444
type: Authorship
author rank in publication: 1
linked author: Elion, Elaine
linked information resource: The major promoter element of rRNA transcription in yeast lies 2 kb upstream.

Authorship 201613
type: Authorship
author rank in publication: 1
linked author: Elion, Elaine
linked information resource: FUS3 represses CLN1 and CLN2 and in concert with KSS1 promotes signal transduction.

Authorship 373538
type: Authorship
author rank in publication: 1
linked author: Elion, Elaine
linked information resource: Analysis of mitogen-activated protein kinase activity in yeast.

Authorship 434475
type: Authorship
author rank in publication: 1
linked author: Elion, Elaine
linked information resource: Ste5: a meeting place for MAP kinases and their associates.

Authorship 545073
type: Authorship
author rank in publication: 1
linked author: Elion, Elaine
linked information resource: Making protein immunoprecipitates.

Authorship 347452
type: Authorship
author rank in publication: 1
linked author: Elion, Elaine
linked information resource: Functional redundancy in the yeast cell cycle: FUS3 and KSS1 have both overlapping and unique functions.

Authorship 533661
type: Authorship
author rank in publication: 4
linked author: Elion, Elaine
linked information resource: Relative dependence of different outputs of the Saccharomyces cerevisiae pheromone response pathway on the MAP kinase Fus3p.

Authorship 41060
type: Authorship
author rank in publication: 4
linked author: Elion, Elaine
linked information resource: Localized feedback phosphorylation of Ste5p scaffold by associated MAPK cascade.

Authorship 43939
type: Authorship
author rank in publication: 5
linked author: Elion, Elaine
linked information resource: A novel functional link between MAP kinase cascades and the Ras/cAMP pathway that regulates survival.

Authorship 73066
type: Authorship
author rank in publication: 1
linked author: Elion, Elaine
linked information resource: FUS3 phosphorylates multiple components of the mating signal transduction cascade: evidence for STE12 and FAR1.

Authorship 861454
type: Authorship
author rank in publication: 6
linked author: Elion, Elaine
linked information resource: Mapping regions in Ste5 that support Msn5-dependent and -independent nuclear export.

Mapping regions in Ste5 that support Msn5-dependent and -independent nuclear export.
PubMed Identifier: 26824509
author list: Hu Z, Wang Y, Yu L, Mahanty SK, Mendoza N, Elion EA
published in: Biochemistry and cell biology = Biochimie et biologie cellulaire
information resource reference: Mapping regions in Ste5 that support Msn5-dependent and -independent nuclear export. Biochem Cell Biol. 2016 Apr; 94(2):109-28.
journal title abbreviation: Biochem Cell Biol
publication date: 2016-01-29T00:00:00
year: 2016
type: Academic Article
type: Article
type: Document
type: Information Resource

Full Professor
sort order: 0
type: Faculty Rank

Instructor
sort order: 4
type: Faculty Rank

Lecturer
sort order: 3
type: Faculty Rank

Other Faculty
sort order: 5
type: Faculty Rank

Cell Cycle Arrest and Signal Transduction in Yeast
end date: 2010-07-31
principal investigator name: ELION, ELAINE A.
start date: 1992-08-01
type: Grant
sponsor award id: R01GM046962

Principal Investigator
type: Researcher Role
researcher role of: Elion, Elaine
contributes to: Cell Cycle Arrest and Signal Transduction in Yeast

Authorship 91935
type: Authorship
author rank in publication: 1
linked author: Elion, Elaine
linked information resource: Detection of protein-protein interactions by coprecipitation.

Authorship 322413
type: Authorship
author rank in publication: 2
linked author: Elion, Elaine
linked information resource: The MAPKKK Ste11 regulates vegetative growth through a kinase cascade of shared signaling components.

Authorship 477850
type: Authorship
author rank in publication: 2
linked author: Elion, Elaine
linked information resource: MAP kinase pathways.

Authorship 336838
type: Authorship
author rank in publication: 5
linked author: Elion, Elaine
linked information resource: Characterization of Fus3 localization: active Fus3 localizes in complexes of varying size and specific activity.

Authorship 513381
type: Authorship
author rank in publication: 1
linked author: Elion, Elaine
linked information resource: Fus2 localizes near the site of cell fusion and is required for both cell fusion and nuclear alignment during zygote formation.

Authorship 55226
type: Authorship
author rank in publication: 1
linked author: Elion, Elaine
linked information resource: Detection of protein-protein interactions by coprecipitation.

The SH3-domain protein Bem1 coordinates mitogen-activated protein kinase cascade activation with cell cycle control in Saccharomyces cerevisiae.
PubMed Identifier: 8754808
author list: Lyons DM, Mahanty SK, Choi KY, Manandhar M, Elion EA
published in: Molecular and cellular biology
information resource reference: The SH3-domain protein Bem1 coordinates mitogen-activated protein kinase cascade activation with cell cycle control in Saccharomyces cerevisiae. Mol Cell Biol. 1996 Aug; 16(8):4095-106.
journal title abbreviation: Mol Cell Biol
publication date: 1996-08-01T00:00:00
year: 1996
type: Academic Article
type: Article
type: Document
type: Information Resource

The osmoregulatory pathway represses mating pathway activity in Saccharomyces cerevisiae: isolation of a FUS3 mutant that is insensitive to the repression mechanism.
PubMed Identifier: 8943326
author list: Hall JP, Cherkasova V, Elion E, Gustin MC, Winter E
published in: Molecular and cellular biology
information resource reference: The osmoregulatory pathway represses mating pathway activity in Saccharomyces cerevisiae: isolation of a FUS3 mutant that is insensitive to the repression mechanism. Mol Cell Biol. 1996 Dec; 16(12):6715-23.
journal title abbreviation: Mol Cell Biol
publication date: 1996-12-01T00:00:00
year: 1996
type: Academic Article
type: Article
type: Document
type: Information Resource

Pheromone response, mating and cell biology.
PubMed Identifier: 11121776
author list: Elion EA
published in: Current opinion in microbiology
information resource reference: Pheromone response, mating and cell biology. Curr Opin Microbiol. 2000 Dec; 3(6):573-81.
journal title abbreviation: Curr Opin Microbiol
publication date: 2000-12-01T00:00:00
year: 2000
type: Academic Article
type: Article
type: Document
type: Information Resource

MAP kinase pathways.
PubMed Identifier: 16105880
author list: Qi M, Elion EA
published in: Journal of cell science
information resource reference: MAP kinase pathways. J Cell Sci. 2005 Aug 15; 118(Pt 16):3569-72.
journal title abbreviation: J Cell Sci
publication date: 2005-08-15T00:00:00
year: 2005
type: Academic Article
type: Article
type: Document
type: Information Resource

Methods for analyzing MAPK cascades.
PubMed Identifier: 17071405
author list: Elion EA
published in: Methods (San Diego, Calif.)
information resource reference: Methods for analyzing MAPK cascades. Methods. 2006 Nov; 40(3):207-8.
journal title abbreviation: Methods
publication date: 2006-11-01T00:00:00
year: 2006
type: Academic Article
type: Article
type: Document
type: Information Resource

A novel functional link between MAP kinase cascades and the Ras/cAMP pathway that regulates survival.
PubMed Identifier: 12867033
author list: Cherkasova VA, McCully R, Wang Y, Hinnebusch A, Elion EA
published in: Current biology : CB
information resource reference: A novel functional link between MAP kinase cascades and the Ras/cAMP pathway that regulates survival. Curr Biol. 2003 Jul 15; 13(14):1220-6.
journal title abbreviation: Curr Biol
publication date: 2003-07-15T00:00:00
year: 2003
type: Academic Article
type: Article
type: Document
type: Information Resource

Detection of protein-protein interactions by coprecipitation.
PubMed Identifier: 18429314
author list: Elion EA
published in: Current protocols in protein science
information resource reference: Detection of protein-protein interactions by coprecipitation. Curr Protoc Protein Sci. 2007 Aug; Chapter 19:19.4.1-19.4.10.
journal title abbreviation: Curr Protoc Protein Sci
publication date: 2007-08-01T00:00:00
year: 2007
type: Academic Article
type: Article
type: Document
type: Information Resource

How to monitor nuclear shuttling.
PubMed Identifier: 12073371
author list: Elion EA
published in: Methods in enzymology
information resource reference: How to monitor nuclear shuttling. Methods Enzymol. 2002; 351:607-22.
journal title abbreviation: Methods Enzymol
publication date: 2002-01-01T00:00:00
year: 2002
type: Academic Article
type: Article
type: Document
type: Information Resource

Nuclear export and plasma membrane recruitment of the Ste5 scaffold are coordinated with oligomerization and association with signal transduction components.
PubMed Identifier: 12808050
author list: Wang Y, Elion EA
published in: Molecular biology of the cell
information resource reference: Nuclear export and plasma membrane recruitment of the Ste5 scaffold are coordinated with oligomerization and association with signal transduction components. Mol Biol Cell. 2003 Jun; 14(6):2543-58.
journal title abbreviation: Mol Biol Cell
publication date: 2003-02-21T00:00:00
year: 2003
type: Academic Article
type: Article
type: Document
type: Information Resource

Functional redundancy in the yeast cell cycle: FUS3 and KSS1 have both overlapping and unique functions.
PubMed Identifier: 1819502
author list: Elion EA, Brill JA, Fink GR
published in: Cold Spring Harbor symposia on quantitative biology
information resource reference: Functional redundancy in the yeast cell cycle: FUS3 and KSS1 have both overlapping and unique functions. Cold Spring Harb Symp Quant Biol. 1991; 56:41-9.
journal title abbreviation: Cold Spring Harb Symp Quant Biol
publication date: 1991-01-01T00:00:00
year: 1991
type: Academic Article
type: Article
type: Document
type: Information Resource

Characterization of Fus3 localization: active Fus3 localizes in complexes of varying size and specific activity.
PubMed Identifier: 10233162
author list: Choi KY, Kranz JE, Mahanty SK, Park KS, Elion EA
published in: Molecular biology of the cell
information resource reference: Characterization of Fus3 localization: active Fus3 localizes in complexes of varying size and specific activity. Mol Biol Cell. 1999 May; 10(5):1553-68.
journal title abbreviation: Mol Biol Cell
publication date: 1999-05-01T00:00:00
year: 1999
type: Academic Article
type: Article
type: Document
type: Information Resource

Differential input by Ste5 scaffold and Msg5 phosphatase route a MAPK cascade to multiple outcomes.
PubMed Identifier: 15192700
author list: Andersson J, Simpson DM, Qi M, Wang Y, Elion EA
published in: The EMBO journal
information resource reference: Differential input by Ste5 scaffold and Msg5 phosphatase route a MAPK cascade to multiple outcomes. EMBO J. 2004 Jul 07; 23(13):2564-76.
journal title abbreviation: EMBO J
publication date: 2004-06-10T00:00:00
year: 2004
type: Academic Article
type: Article
type: Document
type: Information Resource

240 Longwood Ave
type: Address
address line 1: Harvard Medical School
address line 2: B C M P
address line 3: 240 Longwood Ave
city: Boston
postal code: 02115
state or province: MA

Routing MAP kinase cascades.
PubMed Identifier: 9767029
author list: Elion EA
published in: Science (New York, N.Y.)
information resource reference: Routing MAP kinase cascades. Science. 1998 Sep 11; 281(5383):1625-6.
journal title abbreviation: Science
publication date: 1998-09-11T00:00:00
year: 1998
type: Academic Article
type: Article
type: Document
type: Information Resource

Formin-induced actin cables are required for polarized recruitment of the Ste5 scaffold and high level activation of MAPK Fus3.
PubMed Identifier: 15961405
author list: Qi M, Elion EA
published in: Journal of cell science
information resource reference: Formin-induced actin cables are required for polarized recruitment of the Ste5 scaffold and high level activation of MAPK Fus3. J Cell Sci. 2005 Jul 01; 118(Pt 13):2837-48.
journal title abbreviation: J Cell Sci
publication date: 2005-06-16T00:00:00
year: 2005
type: Academic Article
type: Article
type: Document
type: Information Resource

The major promoter element of rRNA transcription in yeast lies 2 kb upstream.
PubMed Identifier: 6096018
author list: Elion EA, Warner JR
published in: Cell
information resource reference: The major promoter element of rRNA transcription in yeast lies 2 kb upstream. Cell. 1984 Dec; 39(3 Pt 2):663-73.
journal title abbreviation: Cell
publication date: 1984-12-01T00:00:00
year: 1984
type: Academic Article
type: Article
type: Document
type: Information Resource

Detection of protein-protein interactions by coprecipitation.
PubMed Identifier: 18265378
author list: Elion EA
published in: Current protocols in molecular biology
information resource reference: Detection of protein-protein interactions by coprecipitation. Curr Protoc Mol Biol. 2006 Nov; Chapter 20:Unit20.5.
journal title abbreviation: Curr Protoc Mol Biol
publication date: 2006-11-01T00:00:00
year: 2006
type: Academic Article
type: Article
type: Document
type: Information Resource

Constructing recombinant DNA molecules by PCR.
PubMed Identifier: 18265404
author list: Elion EA, Marina P, Yu L
published in: Current protocols in molecular biology
information resource reference: Constructing recombinant DNA molecules by PCR. Curr Protoc Mol Biol. 2007 Apr; Chapter 3:Unit 3.17.
journal title abbreviation: Curr Protoc Mol Biol
publication date: 2007-04-01T00:00:00
year: 2007
type: Academic Article
type: Article
type: Document
type: Information Resource

Analysis of mitogen-activated protein kinase activity in yeast.
PubMed Identifier: 20811996
author list: Elion EA, Sahoo R
published in: Methods in molecular biology (Clifton, N.J.)
information resource reference: Analysis of mitogen-activated protein kinase activity in yeast. Methods Mol Biol. 2010; 661:387-99.
journal title abbreviation: Methods Mol Biol
publication date: 2010-01-01T00:00:00
year: 2010
type: Academic Article
type: Article
type: Document
type: Information Resource

FUS3 phosphorylates multiple components of the mating signal transduction cascade: evidence for STE12 and FAR1.
PubMed Identifier: 8334305
author list: Elion EA, Satterberg B, Kranz JE
published in: Molecular biology of the cell
information resource reference: FUS3 phosphorylates multiple components of the mating signal transduction cascade: evidence for STE12 and FAR1. Mol Biol Cell. 1993 May; 4(5):495-510.
journal title abbreviation: Mol Biol Cell
publication date: 1993-05-01T00:00:00
year: 1993
type: Academic Article
type: Article
type: Document
type: Information Resource

POG1, a novel yeast gene, promotes recovery from pheromone arrest via the G1 cyclin CLN2.
PubMed Identifier: 9927449
author list: Leza MA, Elion EA
published in: Genetics
information resource reference: POG1, a novel yeast gene, promotes recovery from pheromone arrest via the G1 cyclin CLN2. Genetics. 1999 Feb; 151(2):531-43.
journal title abbreviation: Genetics
publication date: 1999-02-01T00:00:00
year: 1999
type: Academic Article
type: Article
type: Document
type: Information Resource

The MAP kinase Fus3 associates with and phosphorylates the upstream signaling component Ste5.
PubMed Identifier: 8314085
author list: Kranz JE, Satterberg B, Elion EA
published in: Genes & development
information resource reference: The MAP kinase Fus3 associates with and phosphorylates the upstream signaling component Ste5. Genes Dev. 1994 Feb 01; 8(3):313-27.
journal title abbreviation: Genes Dev
publication date: 1994-02-01T00:00:00
year: 1994
type: Academic Article
type: Article
type: Document
type: Information Resource

Relative dependence of different outputs of the Saccharomyces cerevisiae pheromone response pathway on the MAP kinase Fus3p.
PubMed Identifier: 10101167
author list: Farley FW, Satterberg B, Goldsmith EJ, Elion EA
published in: Genetics
information resource reference: Relative dependence of different outputs of the Saccharomyces cerevisiae pheromone response pathway on the MAP kinase Fus3p. Genetics. 1999 Apr; 151(4):1425-44.
journal title abbreviation: Genetics
publication date: 1999-04-01T00:00:00
year: 1999
type: Academic Article
type: Article
type: Document
type: Information Resource

Nuclear shuttling of yeast scaffold Ste5 is required for its recruitment to the plasma membrane and activation of the mating MAPK cascade.
PubMed Identifier: 10481914
author list: Mahanty SK, Wang Y, Farley FW, Elion EA
published in: Cell
information resource reference: Nuclear shuttling of yeast scaffold Ste5 is required for its recruitment to the plasma membrane and activation of the mating MAPK cascade. Cell. 1999 Aug 20; 98(4):501-12.
journal title abbreviation: Cell
publication date: 1999-08-20T00:00:00
year: 1999
type: Academic Article
type: Article
type: Document
type: Information Resource

Ste5: a meeting place for MAP kinases and their associates.
PubMed Identifier: 14732097
author list: Elion EA
published in: Trends in cell biology
information resource reference: Ste5: a meeting place for MAP kinases and their associates. Trends Cell Biol. 1995 Aug; 5(8):322-7.
journal title abbreviation: Trends Cell Biol
publication date: 1995-08-01T00:00:00
year: 1995
type: Academic Article
type: Article
type: Document
type: Information Resource

FUS3 represses CLN1 and CLN2 and in concert with KSS1 promotes signal transduction.
PubMed Identifier: 1946350
author list: Elion EA, Brill JA, Fink GR
published in: Proceedings of the National Academy of Sciences of the United States of America
information resource reference: FUS3 represses CLN1 and CLN2 and in concert with KSS1 promotes signal transduction. Proc Natl Acad Sci U S A. 1991 Nov 01; 88(21):9392-6.
journal title abbreviation: Proc Natl Acad Sci U S A
publication date: 1991-11-01T00:00:00
year: 1991
type: Academic Article
type: Article
type: Document
type: Information Resource

The Ste5p scaffold.
PubMed Identifier: 11739629
author list: Elion EA
published in: Journal of cell science
information resource reference: The Ste5p scaffold. J Cell Sci. 2001 Nov; 114(Pt 22):3967-78.
journal title abbreviation: J Cell Sci
publication date: 2001-11-01T00:00:00
year: 2001
type: Academic Article
type: Article
type: Document
type: Information Resource

Counteractive control of polarized morphogenesis during mating by mitogen-activated protein kinase Fus3 and G1 cyclin-dependent kinase.
PubMed Identifier: 18256288
author list: Yu L, Qi M, Sheff MA, Elion EA
published in: Molecular biology of the cell
information resource reference: Counteractive control of polarized morphogenesis during mating by mitogen-activated protein kinase Fus3 and G1 cyclin-dependent kinase. Mol Biol Cell. 2008 Apr; 19(4):1739-52.
journal title abbreviation: Mol Biol Cell
publication date: 2008-02-06T00:00:00
year: 2008
type: Academic Article
type: Article
type: Document
type: Information Resource

Making protein immunoprecipitates.
PubMed Identifier: 15173605
author list: Elion EA, Wang Y
published in: Methods in molecular biology (Clifton, N.J.)
information resource reference: Making protein immunoprecipitates. Methods Mol Biol. 2004; 284:1-14.
journal title abbreviation: Methods Mol Biol
publication date: 2004-01-01T00:00:00
year: 2004
type: Academic Article
type: Article
type: Document
type: Information Resource

Detection of protein-protein interactions by coprecipitation.
PubMed Identifier: 18428641
author list: Elion EA
published in: Current protocols in neuroscience
information resource reference: Detection of protein-protein interactions by coprecipitation. Curr Protoc Neurosci. 2006 May; Chapter 5:Unit 5.25.
journal title abbreviation: Curr Protoc Neurosci
publication date: 2006-05-01T00:00:00
year: 2006
type: Academic Article
type: Article
type: Document
type: Information Resource

Fus3p and Kss1p control G1 arrest in Saccharomyces cerevisiae through a balance of distinct arrest and proliferative functions that operate in parallel with Far1p.
PubMed Identifier: 10049917
author list: Cherkasova V, Lyons DM, Elion EA
published in: Genetics
information resource reference: Fus3p and Kss1p control G1 arrest in Saccharomyces cerevisiae through a balance of distinct arrest and proliferative functions that operate in parallel with Far1p. Genetics. 1999 Mar; 151(3):989-1004.
journal title abbreviation: Genetics
publication date: 1999-03-01T00:00:00
year: 1999
type: Academic Article
type: Article
type: Document
type: Information Resource

Cdc24 regulates nuclear shuttling and recruitment of the Ste5 scaffold to a heterotrimeric G protein in Saccharomyces cerevisiae.
PubMed Identifier: 15657049
author list: Wang Y, Chen W, Simpson DM, Elion EA
published in: The Journal of biological chemistry
information resource reference: Cdc24 regulates nuclear shuttling and recruitment of the Ste5 scaffold to a heterotrimeric G protein in Saccharomyces cerevisiae. J Biol Chem. 2005 Apr 01; 280(13):13084-96.
journal title abbreviation: J Biol Chem
publication date: 2005-01-18T00:00:00
year: 2005
type: Academic Article
type: Article
type: Document
type: Information Resource