My research centers on the virology, molecular epidemiology of HIV in Africa along with implementation science work to improve HIV outcomes. I have worked in West Africa since the 1980s and in 2000, I created and directed the AIDS Prevention Initiative in Nigeria (APIN), with a $25 million grant from the Bill & Melinda Gates Foundation. Since 2004, I led the Harvard President’s Emergency Plan for AIDS Relief (PEPFAR) providing prevention, care and HIV antiretroviral therapy in Nigeria, Botswana, and Tanzania. In addition to the capacity building for clinical, laboratory and research capabilities, the program provided treatment for over 160,000 AIDS patients. The PEPFAR program in Nigeria has developed an extensive electronic medical record system that provides real time access to >100,000 patients on antiretroviral treatment. These databases allow us to promote better clinical care and also to answer operational research questions dealing with the efficacy of ART and PMTCT interventions and modulators of this response. Along with Nigerian colleagues, my research group has addressed topics including with HIV co-infections, determinants of ART efficacy and evaluation of PMTCT interventions. In an effort to optimize HIV outcomes we have characterized losses to follow-up in HIV care, treatment and PMTCT interventions and HIV drug resistance. I am currently co-PI for a trial of point of care HIV viral load monitoring to enhance ART outcomes and retention on ART in Nigeria. My long-term research collaborations in West Africa have also incorporated training and research capacity building. I served as the co-principal investigator of the Harvard School of Public Health AITRIP (1988-2013) and I currently lead the Harvard component for NIH Medical Education Partnership Initiatives (MEPI) at the University of Ibadan, Jos and Lagos. These programs seek to enhance research capacity for junior faculty. I have provided mentoring for more than 60 doctoral students or fellows from the US and African countries and I am an honorary faculty member at the University of Ibadan and University of Jos in Nigeria. Following the previous epidemics of Ebola and Zika virus, we have documented the presence of ZIKV infection in Senegalese and Nigerian fever patients over ~ 25 years, demonstrating the endemicity of this unique arbovirus in the region. We have described the longevity, specificity and cross reactivity of T cell responses to ZIKV and DENV NS3. We have also characterized the T cell responses in survivors and exposed health care workers from the 2015 Nigeria EBOV outbreak. We are currently conducting an NIH funded study on the impact of Zika virus infection on pregnancy outcomes in Nigeria. In response to the current SARS-CoV-2 pandemic, I am working with e25Bio an MIT engine laboratory towards development of point of care antigen and antibody assays as well as a pan-subgroup 2b betacoronavirus assays that may serve as zoonotic surveillance tool for future emergent SARS-like viruses.
Mary Woodard Lasker Professor of Health Sciences
Popper SJ, Sarr AD, Guèye-Ndiaye A, Mboup S, Essex ME, Kanki PJ
Low plasma human immunodeficiency virus type 2 viral load is independent of proviral load: low virus production in vivo. J Virol. 2000 Feb; 74(3):1554-7.
Low plasma human immunodeficiency virus type 2 viral load is independent of proviral load: low virus production in vivo.
Sarr AD, Sankalé JL, Hamel DJ, Travers KU, Guèye-Ndiaye A, Essex M, Mboup S, Kanki PJ
Interaction with human immunodeficiency virus (HIV) type 2 predicts HIV type 1 genotype. Virology. 2000 Mar 15; 268(2):402-10.
Interaction with human immunodeficiency virus (HIV) type 2 predicts HIV type 1 genotype.
Agaba PA, Meloni ST, Sule HM, Agbaji OO, Sagay AS, Okonkwo P, Idoko JA, Kanki PJ
Treatment Outcomes Among Older Human Immunodeficiency Virus-Infected Adults in Nigeria. Open Forum Infect Dis. 2017; 4(2):ofx031.
Treatment Outcomes Among Older Human Immunodeficiency Virus-Infected Adults in Nigeria.
Kokkotou EG, Sankale JL, Mani I, Gueye-Ndiaye A, Schwartz D, Essex ME, Mboup S, Kanki PJ
Proceedings of the National Academy of Sciences of the United States of America
In vitro correlates of HIV-2-mediated HIV-1 protection. Proc Natl Acad Sci U S A. 2000 Jun 06; 97(12):6797-802.
In vitro correlates of HIV-2-mediated HIV-1 protection.
Omnibus tests for comparison of competing risks with adjustment for covariate effects. Biometrics. 2001 Sep; 57(3):818-28.
Omnibus tests for comparison of competing risks with adjustment for covariate effects.
Chen YM, Jang YJ, Kanki PJ, Yu QC, Wang JJ, Montali RJ, Samuel KP, Papas TS
Isolation and characterization of simian T-cell leukemia virus type II from New World monkeys. J Virol. 1994 Feb; 68(2):1149-57.
Isolation and characterization of simian T-cell leukemia virus type II from New World monkeys.
Sarr AD, Popper S, Thior I, Hamel DJ, Sankalé JL, Siby T, Marlink R, Essex M, Mboup S, Kanki P
Relation between HIV-2 proviral load and CD4+ lymphocyte count differs in monotypic and dual HIV infections. J Hum Virol. 1999 Jan-Feb; 2(1):45-51.
Relation between HIV-2 proviral load and CD4+ lymphocyte count differs in monotypic and dual HIV infections.
Mani I, Cao H, Hom D, Johnson JL, Mugerwa RD, Travers KU, Caliendo AM, Walker BD, Kanki PJ
Journal of acquired immune deficiency syndromes (1999)
Plasma RNA viral load as measured by the branched DNA and nucleic acid sequence-based amplification assays of HIV-1 subtypes A and D in Uganda. J Acquir Immune Defic Syndr. 1999 Oct 01; 22(2):208-9.
Plasma RNA viral load as measured by the branched DNA and nucleic acid sequence-based amplification assays of HIV-1 subtypes A and D in Uganda.
Sankalé JL, Hamel D, Woolsey A, Traoré T, Dia TC, Guèye-Ndiaye A, Essex M, Mboup T, Kanki P
Molecular evolution of human immunodeficiency virus type 1 subtype A in Senegal: 1988-1997. J Hum Virol. 2000 May-Jun; 3(3):157-64.
Molecular evolution of human immunodeficiency virus type 1 subtype A in Senegal: 1988-1997.
Marlink RG, Ricard D, M'Boup S, Kanki PJ, Romet-Lemonne JL, N'Doye I, Diop K, Simpson MA, Greco F, Chou MJ
Clinical, hematologic, and immunologic cross-sectional evaluation of individuals exposed to human immunodeficiency virus type-2 (HIV-2). AIDS Res Hum Retroviruses. 1988 Apr; 4(2):137-48.
Clinical, hematologic, and immunologic cross-sectional evaluation of individuals exposed to human immunodeficiency virus type-2 (HIV-2).
Tong Q, Sankalé JL, Hadigan CM, Tan G, Rosenberg ES, Kanki PJ, Grinspoon SK, Hotamisligil GS
The Journal of clinical endocrinology and metabolism
Regulation of adiponectin in human immunodeficiency virus-infected patients: relationship to body composition and metabolic indices. J Clin Endocrinol Metab. 2003 Apr; 88(4):1559-64.
Regulation of adiponectin in human immunodeficiency virus-infected patients: relationship to body composition and metabolic indices.
Biologic features of HIV-2. An update. AIDS Clin Rev. 1991; 17-38.
Sarr AD, Eisen G, Guèye-Ndiaye A, Mullins C, Traoré I, Dia MC, Sankalé JL, Faye D, Mboup S, Kanki P
Viral dynamics of primary HIV-1 infection in Senegal, West Africa. J Infect Dis. 2005 May 01; 191(9):1460-7.
Viral dynamics of primary HIV-1 infection in Senegal, West Africa.
Agaba PA, Genberg BL, Sagay AS, Agbaji OO, Meloni ST, Dadem NY, Kolawole GO, Okonkwo P, Kanki PJ, Ware NC
Retention in Differentiated Care: Multiple Measures Analysis for a Decentralized HIV Care and Treatment Program in North Central Nigeria. J AIDS Clin Res. 2018; 9(2).
Retention in Differentiated Care: Multiple Measures Analysis for a Decentralized HIV Care and Treatment Program in North Central Nigeria.
Hoxie JA, Haggarty BS, Bonser SE, Rackowski JL, Shan H, Kanki PJ
Biological characterization of a simian immunodeficiency virus-like retrovirus (HTLV-IV): evidence for CD4-associated molecules required for infection. J Virol. 1988 Aug; 62(8):2557-68.
Biological characterization of a simian immunodeficiency virus-like retrovirus (HTLV-IV): evidence for CD4-associated molecules required for infection.
Dinic L, Akande P, Idigbe EO, Ani A, Onwujekwe D, Agbaji O, Akanbi M, Nwosu R, Adeniyi B, Wahab M, Lekuk C, Kunle-Ope C, Nwokoye N, Kanki P
Genetic determinants of drug-resistant tuberculosis among HIV-infected patients in Nigeria. J Clin Microbiol. 2012 Sep; 50(9):2905-9.
Genetic determinants of drug-resistant tuberculosis among HIV-infected patients in Nigeria.
Herrera BB, Hamel DJ, Oshun P, Akinsola R, Akanmu AS, Chang CA, Eromon P, Folarin O, Adeyemi KT, Happi CT, Lu Y, Ogunsola F, Kanki PJ
A modified anthrax toxin-based enzyme-linked immunospot assay reveals robust T cell responses in symptomatic and asymptomatic Ebola virus exposed individuals. PLoS Negl Trop Dis. 2018 05; 12(5):e0006530.
A modified anthrax toxin-based enzyme-linked immunospot assay reveals robust T cell responses in symptomatic and asymptomatic Ebola virus exposed individuals.
Kanki PJ, Allan J, Barin F, Redfield R, Clumeck N, Quinn T, Mowovondi F, Thiry L, Burny A, Zagury D
Absence of antibodies to HIV-2/HTLV-4 in six central African nations. AIDS Res Hum Retroviruses. 1987; 3(3):317-22.
Absence of antibodies to HIV-2/HTLV-4 in six central African nations.
Gilbert PB, McKeague IW, Eisen G, Mullins C, Guéye-NDiaye A, Mboup S, Kanki PJ
Comparison of HIV-1 and HIV-2 infectivity from a prospective cohort study in Senegal. Stat Med. 2003 Feb 28; 22(4):573-93.
Comparison of HIV-1 and HIV-2 infectivity from a prospective cohort study in Senegal.
Van der Riet FS, Human PA, Cooper DK, Reichart B, Fincham JE, Kalter SS, Kanki PJ, Essex M, Madden DL, Lai-Tung MT
Virological implications of the use of primates in xenotransplantation. Transplant Proc. 1987 Oct; 19(5):4068-9.
Virological implications of the use of primates in xenotransplantation.
Annals of the New York Academy of Sciences
The origins of HIV-1 and HTLV-4/HIV-2. Ann N Y Acad Sci. 1987; 511:370-5.
Sankalé JL, Langevin S, Odaibo G, Meloni ST, Ojesina AI, Olaleye D, Kanki P
The complexity of circulating HIV type 1 strains in Oyo state, Nigeria. AIDS Res Hum Retroviruses. 2007 Aug; 23(8):1020-5.
The complexity of circulating HIV type 1 strains in Oyo state, Nigeria.
Oladokun RE, Awolude O, Brown BJ, Adesina O, Oladokun A, Roberts A, Odaibo G, Osinusi K, Olaleye D, Adewole IF, Kanki P
African journal of medicine and medical sciences
Service uptake and performance of the prevention of mother-to-child transmission (PMTCT) programme in Ibadan, Nigeria. Afr J Med Med Sci. 2010 Jun; 39(2):81-7.
Service uptake and performance of the prevention of mother-to-child transmission (PMTCT) programme in Ibadan, Nigeria.
Isolation of T-lymphotropic retrovirus related to HTLV-III/LAV from wild-caught African green monkeys. Science. 1985 Nov 22; 230(4728):951-4.
Isolation of T-lymphotropic retrovirus related to HTLV-III/LAV from wild-caught African green monkeys.
HIV-1 subtype and reverse transcriptase genotype: role for geographical location and founder effects. PLoS Med. 2006 Dec; 3(12):e540.
HIV-1 subtype and reverse transcriptase genotype: role for geographical location and founder effects.
Ladep NG, Agbaji O, Agaba P, Badung P, Imade G, Sankalé J, Idoko J, Kanki P
Nigerian journal of medicine : journal of the National Association of Resident Doctors of Nigeria
Does immunological status affect the prevalence of Hepatitis C virus infection among HIV/AIDS patients? Niger J Med. 2007 Jul-Sep; 16(3):231-4.
Does immunological status affect the prevalence of Hepatitis C virus infection among HIV/AIDS patients?
Agaba PA, Sule HM, Ojoh RO, Hassan Z, Apena L, Mu'azu MA, Badung B, Agbaji OO, Idoko JA, Kanki P
Presentation and survival of patients with AIDS-related Kaposi's sarcoma in Jos, Nigeria. Int J STD AIDS. 2009 Jun; 20(6):410-3.
Presentation and survival of patients with AIDS-related Kaposi's sarcoma in Jos, Nigeria.
Otegbayo JA, Taiwo BO, Akingbola TS, Odaibo GN, Adedapo KS, Penugonda S, Adewole IF, Olaleye DO, Murphy R, Kanki P
Prevalence of hepatitis B and C seropositivity in a Nigerian cohort of HIV-infected patients. Ann Hepatol. 2008 Apr-Jun; 7(2):152-6.
Prevalence of hepatitis B and C seropositivity in a Nigerian cohort of HIV-infected patients.
Ojesina AI, Chaplin B, Sankalé JL, Murphy R, Idigbe E, Adewole I, Ekong E, Idoko J, Kanki PJ
Interplay of reverse transcriptase inhibitor therapy and gag p6 diversity in HIV type 1 subtype G and CRF02_AG. AIDS Res Hum Retroviruses. 2008 Sep; 24(9):1167-74.
Interplay of reverse transcriptase inhibitor therapy and gag p6 diversity in HIV type 1 subtype G and CRF02_AG.
Herrera BB, Tsai WY, Brites C, Luz E, Pedroso C, Drexler JF, Wang WK, Kanki PJ
T Cell Responses to Nonstructural Protein 3 Distinguish Infections by Dengue and Zika Viruses. mBio. 2018 08 07; 9(4).
T Cell Responses to Nonstructural Protein 3 Distinguish Infections by Dengue and Zika Viruses.
Essex M, Kanki P, Allan J, Barin F, McLane MF, Lee TH, Kitchen L, Homma T, Malone G, Yokota T
HTLV and immunosuppression. Princess Takamatsu Symp. 1984; 15:309-18.
Kane F, Alary M, Ndoye I, Coll AM, M'boup S, Guèye A, Kanki PJ, Joly JR
Temporary expatriation is related to HIV-1 infection in rural Senegal. AIDS. 1993 Sep; 7(9):1261-5.
Temporary expatriation is related to HIV-1 infection in rural Senegal.
Fincham JE, Van der Riet F, Steytler JG, Tung MT, Cooper R, Seier JV, Madden DL, Kanki P, Campbell JA, Taljaard JJ
Increased peripheral lymphocytes, lymphoid hepatitis and anaemia in African vervet monkeys seropositive to retroviruses. J Comp Pathol. 1989 Jul; 101(1):53-68.
Increased peripheral lymphocytes, lymphoid hepatitis and anaemia in African vervet monkeys seropositive to retroviruses.
Daniel MD, Letvin NL, King NW, Kannagi M, Sehgal PK, Hunt RD, Kanki PJ, Essex M, Desrosiers RC
Isolation of T-cell tropic HTLV-III-like retrovirus from macaques. Science. 1985 Jun 07; 228(4704):1201-4.
Isolation of T-cell tropic HTLV-III-like retrovirus from macaques.
Kanki PJ, McLane MF, King NW, Letvin NL, Hunt RD, Sehgal P, Daniel MD, Desrosiers RC, Essex M
Serologic identification and characterization of a macaque T-lymphotropic retrovirus closely related to HTLV-III. Science. 1985 Jun 07; 228(4704):1199-201.
Serologic identification and characterization of a macaque T-lymphotropic retrovirus closely related to HTLV-III.
Sankalé JL, de la Tour RS, Renjifo B, Siby T, Mboup S, Marlink RG, Essex ME, Kanki PJ
Intrapatient variability of the human immunodeficiency virus type 2 envelope V3 loop. AIDS Res Hum Retroviruses. 1995 May; 11(5):617-23.
Intrapatient variability of the human immunodeficiency virus type 2 envelope V3 loop.
Rawizza HE, Chaplin B, Meloni ST, Eisen G, Rao T, Sankalé JL, Dieng-Sarr A, Agbaji O, Onwujekwe DI, Gashau W, Nkado R, Ekong E, Okonkwo P, Murphy RL, Kanki PJ
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
Immunologic criteria are poor predictors of virologic outcome: implications for HIV treatment monitoring in resource-limited settings. Clin Infect Dis. 2011 Dec; 53(12):1283-90.
Immunologic criteria are poor predictors of virologic outcome: implications for HIV treatment monitoring in resource-limited settings.
Kanki PJ, M'Boup S, Ricard D, Barin F, Denis F, Boye C, Sangare L, Travers K, Albaum M, Marlink R
Human T-lymphotropic virus type 4 and the human immunodeficiency virus in West Africa. Science. 1987 May 15; 236(4803):827-31.
Human T-lymphotropic virus type 4 and the human immunodeficiency virus in West Africa.
Hirsch V, Riedel N, Kornfeld H, Kanki PJ, Essex M, Mullins JI
Cross-reactivity to human T-lymphotropic virus type III/lymphadenopathy-associated virus and molecular cloning of simian T-cell lymphotropic virus type III from African green monkeys. Proc Natl Acad Sci U S A. 1986 Dec; 83(24):9754-8.
Cross-reactivity to human T-lymphotropic virus type III/lymphadenopathy-associated virus and molecular cloning of simian T-cell lymphotropic virus type III from African green monkeys.
Chaplin B, Akanmu AS, Inzaule SC, Samuels JO, Okonkwo P, Ilesanmi O, Adewole IFA, Asadu C, Khamofu H, Mpazanje R, Ndembi N, Odafe S, Sigaloff KCE, Ngige EN, Abatta EO, Akinbiyi G, Dakum P, Rinke de Wit TF, Kanki P
The Journal of antimicrobial chemotherapy
Association between HIV-1 subtype and drug resistance in Nigerian infants. J Antimicrob Chemother. 2019 01 01; 74(1):172-176.
Association between HIV-1 subtype and drug resistance in Nigerian infants.
Erdman SE, Kanki PJ, Moore FM, Brown SA, Kawasaki TA, Mikule KW, Travers KU, Badylak SF, Fox JG
Clusters of lymphoma in ferrets. Cancer Invest. 1996; 14(3):225-30.
Shea A, Sarr DA, Jones N, Penning L, Eisen G, Gueye-Ndiaye A, Mboup S, Kanki P, Cao H
CCR5 receptor expression is down-regulated in HIV type 2 infection: implication for viral control and protection. AIDS Res Hum Retroviruses. 2004 Jun; 20(6):630-5.
CCR5 receptor expression is down-regulated in HIV type 2 infection: implication for viral control and protection.
Ojesina AI, Mullins C, Imade G, Samuels J, Sankalé JL, Pam S, Sagay S, Idoko J, Kanki PJ
Characterization of HIV type 1 reverse transcriptase mutations in infants infected by mothers who received peripartum nevirapine prophylaxis in Jos, Nigeria. AIDS Res Hum Retroviruses. 2007 Dec; 23(12):1587-92.
Characterization of HIV type 1 reverse transcriptase mutations in infants infected by mothers who received peripartum nevirapine prophylaxis in Jos, Nigeria.
Donnelly C, Leisenring W, Kanki P, Awerbuch T, Sandberg S
Comparison of transmission rates of HIV-1 and HIV-2 in a cohort of prostitutes in Senegal. Bull Math Biol. 1993; 55(4):731-43.
Comparison of transmission rates of HIV-1 and HIV-2 in a cohort of prostitutes in Senegal.
Strong CL, Lanchy JM, Dieng-Sarr A, Kanki PJ, Lodmell JS
A 5'UTR-spliced mRNA isoform is specialized for enhanced HIV-2 gag translation. J Mol Biol. 2009 Aug 14; 391(2):426-37.
A 5'UTR-spliced mRNA isoform is specialized for enhanced HIV-2 gag translation.
Erratum for Herrera et al., "T Cell Responses to Nonstructural Protein 3 Distinguish Infections by Dengue and Zika Viruses". mBio. 2018 10 23; 9(5).
Erratum for Herrera et al., "T Cell Responses to Nonstructural Protein 3 Distinguish Infections by Dengue and Zika Viruses".
Allan JS, Coligan JE, Lee TH, Barin F, Kanki PJ, M'Boup S, McLane MF, Groopman JE, Essex M
Immunogenic nature of a Pol gene product of HTLV-III/LAV. Blood. 1987 Jan; 69(1):331-3.
Immunogenic nature of a Pol gene product of HTLV-III/LAV.
Kokkotou E, Philippon V, Guèye-Ndiaye A, Mboup S, Wang WK, Essex M, Kanki P
Role of the CCR5 delta 32 allele in resistance to HIV-1 infection in west Africa. J Hum Virol. 1998 Nov-Dec; 1(7):469-74.
Role of the CCR5 delta 32 allele in resistance to HIV-1 infection in west Africa.
Ebonyi AO, Oguche S, Meloni ST, Sagay SA, Kyriacou DN, Achenbach CJ, Agbaji OO, Oyebode TA, Okonkwo P, Idoko JA, Kanki PJ
Predictors of Mortality in a Clinic Cohort of HIV-1 Infected Children Initiated on Antiretroviral Therapy in Jos, Nigeria. J AIDS Clin Res. 2014; 5(12).
Predictors of Mortality in a Clinic Cohort of HIV-1 Infected Children Initiated on Antiretroviral Therapy in Jos, Nigeria.
Laboratory diagnosis of HIV-1 and HIV-2 in Africa. AIDS. 1991; 5 Suppl 1:S93-101.
Laboratory diagnosis of HIV-1 and HIV-2 in Africa.
Hanson A, Sarr AD, Shea A, Jones N, Mboup S, Kanki P, Cao H
Distinct profile of T cell activation in HIV type 2 compared to HIV type 1 infection: differential mechanism for immunoprotection. AIDS Res Hum Retroviruses. 2005 Sep; 21(9):791-8.
Distinct profile of T cell activation in HIV type 2 compared to HIV type 1 infection: differential mechanism for immunoprotection.
Marlink R, Kanki P, Thior I, Travers K, Eisen G, Siby T, Traore I, Hsieh CC, Dia MC, Gueye EH
Reduced rate of disease development after HIV-2 infection as compared to HIV-1. Science. 1994 Sep 09; 265(5178):1587-90.
Reduced rate of disease development after HIV-2 infection as compared to HIV-1.
Homma T, Kanki PJ, King NW, Hunt RD, O'Connell MJ, Letvin NL, Daniel MD, Desrosiers RC, Yang CS, Essex M
Lymphoma in macaques: association with virus of human T lymphotrophic family. Science. 1984 Aug 17; 225(4663):716-8.
Lymphoma in macaques: association with virus of human T lymphotrophic family.
MacNeil A, Sankale JL, Meloni ST, Sarr AD, Mboup S, Kanki P
Long-term intrapatient viral evolution during HIV-2 infection. J Infect Dis. 2007 Mar 01; 195(5):726-33.
Long-term intrapatient viral evolution during HIV-2 infection.
Simian T-lymphotropic viruses and related human viruses. Vet Microbiol. 1988 Jul; 17(3):309-14.
Simian T-lymphotropic viruses and related human viruses.
Agbaji O, Thio CL, Meloni S, Graham C, Muazu M, Nimzing L, Idoko J, Sankalé JL, Ekong E, Murphy R, Kanki P, Hawkins C
Impact of hepatitis C virus on HIV response to antiretroviral therapy in Nigeria. J Acquir Immune Defic Syndr. 2013 Feb 01; 62(2):204-7.
Impact of hepatitis C virus on HIV response to antiretroviral therapy in Nigeria.
West African human retroviruses related to STLV-III. AIDS. 1987 Sep; 1(3):141-5.
West African human retroviruses related to STLV-III.
Cao H, Kanki P, Sankalé JL, Dieng-Sarr A, Mazzara GP, Kalams SA, Korber B, Mboup S, Walker BD
Cytotoxic T-lymphocyte cross-reactivity among different human immunodeficiency virus type 1 clades: implications for vaccine development. J Virol. 1997 Nov; 71(11):8615-23.
Cytotoxic T-lymphocyte cross-reactivity among different human immunodeficiency virus type 1 clades: implications for vaccine development.
Sarr AD, Sankalé JL, Guèye-Ndiaye A, Essex M, Mboup S, Kanki PJ
Genetic analysis of HIV type 2 in monotypic and dual HIV infections. AIDS Res Hum Retroviruses. 2000 Feb 10; 16(3):295-8.
Genetic analysis of HIV type 2 in monotypic and dual HIV infections.
In 1947, Zika virus (ZIKV) was discovered in Africa and was considered an obscure flavivirus, however from 2015-17, 70 countries reported mosquito-borne ZIKV with intense epidemics sweeping South America and the Caribbean. Now recognized to have caused congenital microcephaly, various ocular and neurologic lesions, a central question remains as to whether the African ZIKV virus poses similar epidemiologic and pathogenic risk for African populations. In Nigeria, we identify ZIKV infected pregnant women and prospectively follow them to determine the consequences to their babies.
Uncertainty in artificial intelligence : proceedings of the ... conference. Conference on Uncertainty in Artificial Intelligence
Estimation of Personalized Effects Associated With Causal Pathways. Uncertain Artif Intell. 2018 Aug; 2018.
Estimation of Personalized Effects Associated With Causal Pathways.
Okunade KS, John-Olabode S, Akinsola OJ, Akinajo O, Akanmu SA, Kanki PJ
Effects of selenium supplementation on pregnancy outcome and disease progression in HIV-infected pregnant women in Lagos, Nigeria: Study protocol for a randomised, double-blind, placebo-controlled trial. Medicine (Baltimore). 2019 Jan; 98(3):e12735.
Effects of selenium supplementation on pregnancy outcome and disease progression in HIV-infected pregnant women in Lagos, Nigeria: Study protocol for a randomised, double-blind, placebo-controlled trial.
Ulenga NK, Sarr AD, Thakore-Meloni S, Sankalé JL, Eisen G, Kanki PJ
Relationship between human immunodeficiency type 1 infection and expression of human APOBEC3G and APOBEC3F. J Infect Dis. 2008 Aug 15; 198(4):486-92.
Relationship between human immunodeficiency type 1 infection and expression of human APOBEC3G and APOBEC3F.
Idoko J, Meloni S, Muazu M, Nimzing L, Badung B, Hawkins C, Sankalé JL, Ekong E, Murphy R, Kanki P, Thio CL
Impact of hepatitis B virus infection on human immunodeficiency virus response to antiretroviral therapy in Nigeria. Clin Infect Dis. 2009 Oct 15; 49(8):1268-73.
Impact of hepatitis B virus infection on human immunodeficiency virus response to antiretroviral therapy in Nigeria.
Akinyemi JO, Awolude OA, Adewole IF, Kanki PJ
Journal of infection in developing countries
Condom use among antiretroviral therapy patients in Ibadan, Nigeria. J Infect Dev Ctries. 2010 Sep 03; 4(8):495-502.
Condom use among antiretroviral therapy patients in Ibadan, Nigeria.
Agbaji OO, Abah IO, Ebonyi AO, Gimba ZM, Abene EE, Gomerep SS, Falang KD, Anejo-Okopi J, Agaba PA, Ugoagwu PO, Agaba EI, Imade GE, Sagay AS, Okonkwo P, Idoko JA, Kanki PJ
Journal of the International Association of Providers of AIDS Care
Long Term Exposure to Tenofovir Disoproxil Fumarate-Containing Antiretroviral Therapy Is Associated with Renal Impairment in an African Cohort of HIV-Infected Adults. J Int Assoc Provid AIDS Care. 2019 Jan-Dec; 18:2325958218821963.
Long Term Exposure to Tenofovir Disoproxil Fumarate-Containing Antiretroviral Therapy Is Associated with Renal Impairment in an African Cohort of HIV-Infected Adults.
Abah IO, Ncube NBQ, Bradley HA, AgbaJi OO, Kanki P
Antiretroviral Therapy-associated Adverse Drug Reactions and their Effects on Virologic Failure- A Retrospective Cohort Study in Nigeria. Curr HIV Res. 2018; 16(6):436-446.
Antiretroviral Therapy-associated Adverse Drug Reactions and their Effects on Virologic Failure- A Retrospective Cohort Study in Nigeria.
Meloni ST, Agbaji O, Chang CA, Agaba P, Imade G, Oguche S, Mukhtar A, Mitruka K, Cox MH, Zee A, Kanki P
The role of point-of-care viral load monitoring in achieving the target of 90% suppression in HIV-infected patients in Nigeria: study protocol for a randomized controlled trial. BMC Infect Dis. 2019 May 02; 19(1):368.
The role of point-of-care viral load monitoring in achieving the target of 90% suppression in HIV-infected patients in Nigeria: study protocol for a randomized controlled trial.
Harvard T.H. Chan School of Public Health
Richard Saltonstall Professor of Population Sciences, and Professor of Nutrition, Epidemiology, and Global Health
Professor of Immunology and Infectious Diseases, Emeritus
Rawizza HE, Darin KM, Oladokun R, Brown B, Ogunbosi B, David N, Akanmu S, Olaitan O, Chang C, Scarsi KK, Okonkwo P, Kanki PJ
Safety and efficacy of rifabutin among HIV/TB-coinfected children on lopinavir/ritonavir-based ART. J Antimicrob Chemother. 2019 09 01; 74(9):2707-2715.
Safety and efficacy of rifabutin among HIV/TB-coinfected children on lopinavir/ritonavir-based ART.
Irene Heinz Given Professor of Immunology and Infectious Diseases
Mary Woodard Lasker Professor of Health Sciences, Emeritus
Balogun MR, Sekoni AO, Meloni ST, Odukoya OO, Onajole AT, Longe-Peters OA, Ogunsola FT, Kanki PJ
Predictors of tuberculosis knowledge, attitudes and practices in urban slums in Nigeria: a cross-sectional study. Pan Afr Med J. 2019; 32:60.
Predictors of tuberculosis knowledge, attitudes and practices in urban slums in Nigeria: a cross-sectional study.
Harriet Ryan Albee Professor of Medicine
Balogun M, Meloni ST, Igwilo UU, Roberts A, Okafor I, Sekoni A, Ogunsola F, Kanki PJ, Akanmu S
Status of HIV-infected patients classified as lost to follow up from a large antiretroviral program in southwest Nigeria. PLoS One. 2019; 14(7):e0219903.
Status of HIV-infected patients classified as lost to follow up from a large antiretroviral program in southwest Nigeria.
Koofhethile CK, Moyo S, Kotokwe KP, Mokgethi P, Muchoba L, Mokgweetsi S, Gaolathe T, Makhema J, Shapiro R, Lockman S, Kanki P, Essex M, Gaseitsiwe S, de Oliveira T, Novitsky V
Undetectable proviral deoxyribonucleic acid in an adolescent perinatally infected with human immunodeficiency virus-1C and on long-term antiretroviral therapy resulted in viral rebound following antiretroviral therapy termination: A case report with implications for clinical care. Medicine (Baltimore). 2019 Nov; 98(47):e18014.
Undetectable proviral deoxyribonucleic acid in an adolescent perinatally infected with human immunodeficiency virus-1C and on long-term antiretroviral therapy resulted in viral rebound following antiretroviral therapy termination: A case report with implications for clinical care.
Onwuamah CK, Okpokwu J, Audu R, Imade G, Meloni ST, Okwuraiwe A, Chebu P, Musa AZ, Chaplin B, Dalhatu I, Agbaji O, Samuels J, Ezechi O, Ahmed M, Odaibo G, Olaleye DO, Okonkwo P, Salako BL, Raizes E, Yang C, Kanki PJ, Idigbe EO
Low levels of HIV-1 drug resistance mutations in patients who achieved viral re-suppression without regimen switch: a retrospective study. BMC Microbiol. 2020 01 20; 20(1):17.
Low levels of HIV-1 drug resistance mutations in patients who achieved viral re-suppression without regimen switch: a retrospective study.
Miles CH, Shpitser I, Kanki P, Meloni S, Tchetgen EJT
Journal of the American Statistical Association
Quantifying an Adherence Path-Specific Effect of Antiretroviral Therapy in the Nigeria PEPFAR Program. J Am Stat Assoc. 2017; 112(520):1443-1452.
Quantifying an Adherence Path-Specific Effect of Antiretroviral Therapy in the Nigeria PEPFAR Program.
Nazziwa J, Faria NR, Chaplin B, Rawizza H, Kanki P, Dakum P, Abimiku A, Charurat M, Ndembi N, Esbjörnsson J
Characterisation of HIV-1 Molecular Epidemiology in Nigeria: Origin, Diversity, Demography and Geographic Spread. Sci Rep. 2020 02 26; 10(1):3468.
Characterisation of HIV-1 Molecular Epidemiology in Nigeria: Origin, Diversity, Demography and Geographic Spread.
Ogunsola FT, Odukoya OO, Banigbe B, Caleb-Adepoju SO, Folarin O, Afolabi BB, Okubadejo NU, Adeyemo WL, Akanmu AS, Osuntoki A, Okonkwo P, Murphy R, Kanki P
A preprogram appraisal of factors influencing research productivity among faculty at college of medicine, University of Lagos. Ann Afr Med. 2020 Apr-Jun; 19(2):124-130.
A preprogram appraisal of factors influencing research productivity among faculty at college of medicine, University of Lagos.
Meloni ST, Agaba P, Chang CA, Yiltok E, Oguche S, Ejeliogu E, Agbaji O, Okonkwo P, Kanki PJ
Longitudinal evaluation of adherence, retention, and transition patterns of adolescents living with HIV in Nigeria. PLoS One. 2020; 15(7):e0236801.
Longitudinal evaluation of adherence, retention, and transition patterns of adolescents living with HIV in Nigeria.
Ogbenna AA, Meloni S, Inzaule S, Hamers RL, Sigaloff K, Osibogun A, Adeyemo TA, Okonkwo P, Samuels JO, Kanki PJ, Rinke de Wit TF, Akanmu AS
The impact of HIV-1 subtypes on virologic and immunologic treatment outcomes at the Lagos University Teaching Hospital: A longitudinal evaluation. PLoS One. 2020; 15(8):e0238027.
The impact of HIV-1 subtypes on virologic and immunologic treatment outcomes at the Lagos University Teaching Hospital: A longitudinal evaluation.
Koofhethile CK, Moyo S, Kotokwe KP, Chang C, Mokgethi P, Muchoba L, Mokgweetsi S, Makhema J, Lockman S, Gaseitsiwe S, de Oliveira T, Essex M, Shapiro R, Kanki P, Novitsky V
Detection of Inducible Replication-Competent HIV-1 Subtype C Provirus Despite Long-Term Antiretroviral Treatment in Perinatally Infected Adolescents in Botswana. AIDS Res Hum Retroviruses. 2021 01; 37(1):16-23.
Detection of Inducible Replication-Competent HIV-1 Subtype C Provirus Despite Long-Term Antiretroviral Treatment in Perinatally Infected Adolescents in Botswana.
University of Minnesota School of Veterinary Medicine
University of Minnesota School of Veterinary Medicine,
O'Sullivan MJ, Mitchel JA, Mwase C, McGill M, Kanki P, Park JA
American journal of physiology. Lung cellular and molecular physiology
In well-differentiated primary human bronchial epithelial cells, TGF-ß1 and TGF-ß2 induce expression of furin. Am J Physiol Lung Cell Mol Physiol. 2021 02 01; 320(2):L246-L253.
In well-differentiated primary human bronchial epithelial cells, TGF-ß1 and TGF-ß2 induce expression of furin.
Okunade KS, Olowoselu OF, John-Olabode S, Hassan BO, Akinsola OJ, Nwogu CM, Ugwu AO, Moses OE, Rabiu KA, Ajepe A, Adenekan MA, Adejimi AA, Akanmu SA, Kanki PJ
International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics
Effects of selenium supplementation on pregnancy outcomes and disease progression in HIV-infected pregnant women in Lagos: A randomized controlled trial. Int J Gynaecol Obstet. 2021 Jun; 153(3):533-541.
Effects of selenium supplementation on pregnancy outcomes and disease progression in HIV-infected pregnant women in Lagos: A randomized controlled trial.
Oluwole EO, Adeyemo TA, Osanyin GE, Odukoya OO, Kanki PJ, Afolabi BB
Feasibility and acceptability of early infant screening for sickle cell disease in Lagos, Nigeria-A pilot study. PLoS One. 2020; 15(12):e0242861.
Feasibility and acceptability of early infant screening for sickle cell disease in Lagos, Nigeria-A pilot study.
Rawizza HE, Oladokun R, Ejeliogu E, Oguche S, Ogunbosi BO, Agbaji O, Odaibo G, Imade G, Olaleye D, Wiesner L, Darin KM, Okonkwo P, Kanki PJ, Scarsi KK, McIlleron HM
Rifabutin pharmacokinetics and safety among TB/HIV-coinfected children receiving lopinavir/ritonavir-containing second-line ART. J Antimicrob Chemother. 2021 02 11; 76(3):710-717.
Rifabutin pharmacokinetics and safety among TB/HIV-coinfected children receiving lopinavir/ritonavir-containing second-line ART.
A hybrid of facility and community based interventions, that will expand access to comprehensive HIV prevention, care and treatment services in eight (8) states of Benue, Ekiti, Lagos, Ogun, Ondo, Osun, Oyo and Plateau in Nigeria. The program, funded by PEPFAR through CDC, aims to contribute to the UNAIDS 90-90-90 goal of epidemic control in Nigeria.
The College of Medicine University of Lagos supports the continuation of research capacity building of the Medical Education Partnership Initiative in Nigeria. BRAINS will develop a MS curriculum for junior faculty, transitioned to a sustainable e-learning format and support a robust mentored research program in HIV outcomes, Community Medicine, Genomics and Biomedical Engineering.
Research training for career development of junior faculty in Medical Education Partnership Initiative (MEPI) to support and energize research training programs for junior faculty at the University of Jos and Ahmadu Bello University, to increase their capacity to participate in and carry out locally relevant research that contributes to improved human health and to foster the next generation of faculty researchers in Nigeria.
Pathogenesis of SARS-CoV-2 infection in primary human airway epithelial cells: Role of age Primary bronchial epithelial cells are the major target of SARS-CoV-2 infection. We will characterize viral replication, apoptosis and pyroptosis in cells from young and older human donors cultured in air-liquid interface.
Support of Training and Mentoring in Nigeria for Academics (STAMINA)
Improving Comprehensive AIDS Response Enhanced for Sustainability (iCARES)
Building Research and Innovation in Nigeria’s Science (BRAINS)
Isaac AO, Wetkos DD, Oche AO, Godwin I, Phyllis K, John AC
Prevalence of Cytochrome P450 2B6 Single Nucleotide Polymorphism in an HIV-Positive Cohort in Jos, Nigeria: Implication for HIV Therapy. Niger J Clin Pract. 2020 Dec; 23(12):1736-1743.
Prevalence of Cytochrome P450 2B6 Single Nucleotide Polymorphism in an HIV-Positive Cohort in Jos, Nigeria: Implication for HIV Therapy.
Rosemary A, Chika O, Jonathan O, Godwin I, Georgina O, Azuka O, Zaidat M, Philippe C, Oliver E, Oche A, David O, Jay S, Ibrahim D, Mukhtar A, Joshua D, Chunfu Y, Elliot R, Beth C, Phyllis K, Emmanuel I
Genotyping performance evaluation of commercially available HIV-1 drug resistance test. PLoS One. 2018; 13(6):e0198246.
Genotyping performance evaluation of commercially available HIV-1 drug resistance test.
Miles BCH, Shpitser I, Kanki P, Meloni S, Tchetgen EJT
On semiparametric estimation of a path-specific effect in the presence of mediator-outcome confounding. Biometrika. 2020 Mar; 107(1):159-172.
On semiparametric estimation of a path-specific effect in the presence of mediator-outcome confounding.
Ige OO, Afolanranmi TO, Yilgwan CS, Ayatse F, Nkereuwem E, Sagay AS, Kanki P, Bode-Thomas F
Study of congenital heart defects among neonates in Jos, Nigeria: prevalence and spectrum. Cardiovasc J Afr. 2021 Jan-Feb 23; 32(1):21-27.
Study of congenital heart defects among neonates in Jos, Nigeria: prevalence and spectrum.
Farinre O, Gounder K, Reddy T, Tongo M, Hare J, Chaplin B, Gilmour J, Kanki P, Mann JK, Ndung'u T
Subtype-specific differences in Gag-protease replication capacity of HIV-1 isolates from East and West Africa. Retrovirology. 2021 05 05; 18(1):11.
Subtype-specific differences in Gag-protease replication capacity of HIV-1 isolates from East and West Africa.
Osaigbovo GO, Amusa GA, Salaam AJ, Imoh LC, Okeke EN, Zoakah AI, Kanki P, Sagay SA
Predictors and Prognosis of Stroke in Jos, North-Central Nigeria. West Afr J Med. 2021 May 29; 38(5):478-485.
Predictors and Prognosis of Stroke in Jos, North-Central Nigeria.
Assefa N, Sié A, Wang D, Korte ML, Hemler EC, Abdullahi YY, Lankoande B, Millogo O, Chukwu A, Workneh F, Kanki P, Baernighausen T, Berhane Y, Fawzi WW, Oduola A
The American journal of tropical medicine and hygiene
Reported Barriers to Healthcare Access and Service Disruptions Caused by COVID-19 in Burkina Faso, Ethiopia, and Nigeria: A Telephone Survey. Am J Trop Med Hyg. 2021 Jun 23; 105(2):323-330.
Reported Barriers to Healthcare Access and Service Disruptions Caused by COVID-19 in Burkina Faso, Ethiopia, and Nigeria: A Telephone Survey.
Bello FO, Akanmu AS, Adeyemo TA, Idowu BM, Okonkwo P, Kanki PJ
Southern African journal of HIV medicine
Derangement of protein S and C4b-binding protein levels as acquired thrombophilia in HIV-infected adult Nigerians. South Afr J HIV Med. 2021; 22(1):1253.
Derangement of protein S and C4b-binding protein levels as acquired thrombophilia in HIV-infected adult Nigerians.
Oladele RO, Otu AA, Balogun OJ, Babalola OM, Nwosu AO, Iyabo Osaigbovo I, Gbajabiamila T, Irurhe NK, Fayemiwo SA, Shettima SA, Uwaezuoke NS, Edwin CP, Ayanbeku TS, Okaa JU, Elikwu CJ, Denning DW, Kanki PJ, Ogunsola FT
Therapeutic advances in infectious disease
Standardization of Aspergillus IgG diagnostic cutoff in Nigerians. Ther Adv Infect Dis. 2021 Jan-Dec; 8:20499361211050158.
Standardization of Aspergillus IgG diagnostic cutoff in Nigerians.
Acceptability of and Preferences for Long-Acting Injectable HIV PrEP and Other PrEP Modalities among Sexual Minority Men in Nigeria, Africa. AIDS Behav. 2022 Jul; 26(7):2363-2375.
Acceptability of and Preferences for Long-Acting Injectable HIV PrEP and Other PrEP Modalities among Sexual Minority Men in Nigeria, Africa.
Abah IO, Dayom WD, Dangiwa DA, Aderemi-Williams R, Anejo-Okopi J, Agbaji OO, Kanki P, Aguiyi JC
Comparative incidence of adverse drug reaction during the first and subsequent year of antiretroviral therapy in a Nigerian HIV infected Cohort. Afr Health Sci. 2021 Sep; 21(3):1027-1039.
Comparative incidence of adverse drug reaction during the first and subsequent year of antiretroviral therapy in a Nigerian HIV infected Cohort.
Stanley S, Hamel DJ, Wolf ID, Riedel S, Dutta S, Contreras E, Callahan CJ, Cheng A, Arnaout R, Kirby JE, Kanki PJ
Limit of Detection for Rapid Antigen Testing of the SARS-CoV-2 Omicron and Delta Variants of Concern Using Live-Virus Culture. J Clin Microbiol. 2022 05 18; 60(5):e0014022.
Limit of Detection for Rapid Antigen Testing of the SARS-CoV-2 Omicron and Delta Variants of Concern Using Live-Virus Culture.
Chaplin B, Agbaji O, Reyes Nieva H, Olatunde B, Chang C, Mitruka K, Sule H, Dajel T, Zee A, Ahmed ML, Ahmed I, Okonkwo P, Rawizza H, Kanki P
Timeliness of Point-of-Care Viral Load Results Improves Human Immunodeficiency Virus Monitoring in Nigeria. Clin Infect Dis. 2023 02 08; 76(3):e671-e680.
Timeliness of Point-of-Care Viral Load Results Improves Human Immunodeficiency Virus Monitoring in Nigeria.
Kirby JE, Riedel S, Dutta S, Arnaout R, Cheng A, Ditelberg S, Hamel DJ, Chang CA, Kanki PJ
Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases
Sars-Cov-2 antigen tests predict infectivity based on viral culture: comparison of antigen, PCR viral load, and viral culture testing on a large sample cohort. Clin Microbiol Infect. 2023 Jan; 29(1):94-100.
Sars-Cov-2 antigen tests predict infectivity based on viral culture: comparison of antigen, PCR viral load, and viral culture testing on a large sample cohort.
Chang C, Agbaji O, Mitruka K, Olatunde B, Sule H, Dajel T, Zee A, Ahmed ML, Ahmed I, Okonkwo P, Chaplin B, Kanki P
Clinical Outcomes in a Randomized Controlled Trial Comparing Point-of-Care With Standard Human Immunodeficiency Virus (HIV) Viral Load Monitoring in Nigeria. Clin Infect Dis. 2023 02 08; 76(3):e681-e691.
Clinical Outcomes in a Randomized Controlled Trial Comparing Point-of-Care With Standard Human Immunodeficiency Virus (HIV) Viral Load Monitoring in Nigeria.
Intersectional Stigma and HIV Continuum Outcomes Among Sexual Minority Men in Sub-Saharan Africa: A Conceptual Framework. Am J Public Health. 2022 06; 112(S4):S374-S376.
Intersectional Stigma and HIV Continuum Outcomes Among Sexual Minority Men in Sub-Saharan Africa: A Conceptual Framework.
Ogunsola FT, Sekoni A, Akanmu AS, Adeyemo WL, Osuntoki A, Manga-Atangana B, Afolabi BB, Okubadejo NU, Emmanuel M, Caleb-Adepoju SO, Folarin O, Okonkwo P, Murphy RL, Kanki P
Achieving a robust mentoring and research capacity program in a LMIC - the BRAINS faculty development model. BMC Med Educ. 2023 Jul 20; 23(1):522.
Achieving a robust mentoring and research capacity program in a LMIC - the BRAINS faculty development model.
Akanmu S, Herrera BB, Chaplin B, Ogunsola S, Osibogun A, Onawoga F, John-Olabode S, Akase IE, Nwosu A, Hamel DJ, Chang CA, Kanki PJ
High SARS-CoV-2 seroprevalence in Lagos, Nigeria with robust antibody and cellular immune responses. J Clin Virol Plus. 2023 Aug; 3(3):100156.
High SARS-CoV-2 seroprevalence in Lagos, Nigeria with robust antibody and cellular immune responses.
Ogwuche J, Chang CA, Ige O, Sagay AS, Chaplin B, Kahansim ML, Paul M, Elujoba M, Imade G, Kweashi G, Dai YC, Hsieh SC, Wang WK, Hamel DJ, Kanki PJ
medRxiv : the preprint server for health sciences
Arbovirus surveillance in pregnant women in north-central Nigeria, 2019-2022. medRxiv. 2023 Aug 08.
Arbovirus surveillance in pregnant women in north-central Nigeria, 2019-2022.
Sagay AS, Hsieh SC, Dai YC, Chang CA, Ogwuche J, Ige OO, Kahansim ML, Chaplin B, Imade G, Elujoba M, Paul M, Hamel DJ, Furuya H, Khoury R, Boaventura VS, de Moraes L, Kanki PJ, Wang WK
Chikungunya virus antepartum transmission and abnormal infant outcomes in Nigeria. medRxiv. 2023 Aug 09.
Chikungunya virus antepartum transmission and abnormal infant outcomes in Nigeria.
Chen GH, Dai YC, Hsieh SC, Tsai JJ, Sy AK, Jiz M, Pedroso C, Brites C, Netto EM, Kanki PJ, Saunders DRD, Vanlandingham DL, Higgs S, Huang YS, Wang WK
Detection of anti-premembrane antibody as a specific marker of four flavivirus serocomplexes and its application to serosurveillance in endemic regions. medRxiv. 2023 Sep 25.
Detection of anti-premembrane antibody as a specific marker of four flavivirus serocomplexes and its application to serosurveillance in endemic regions.
Koofhethile CK, Gao C, Chang C, Lian X, Shapiro R, Yu XG, Lichterfeld M, Kanki PJ
The HIV-2 proviral landscape is dominated by defective proviruses. AIDS. 2024 03 01; 38(3):309-316.
The HIV-2 proviral landscape is dominated by defective proviruses.
Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology
Arbovirus surveillance in pregnant women in north-central Nigeria, 2019-2022. J Clin Virol. 2023 12; 169:105616.
Sagay AS, Hsieh SC, Dai YC, Chang CA, Ogwuche J, Ige OO, Kahansim ML, Chaplin B, Imade G, Elujoba M, Paul M, Hamel DJ, Furuya H, Khouri R, Boaventura VS, de Moraes L, Kanki PJ, Wang WK
International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases
Chikungunya virus antepartum transmission and abnormal infant outcomes in a cohort of pregnant women in Nigeria. Int J Infect Dis. 2024 Feb; 139:92-100.
Chikungunya virus antepartum transmission and abnormal infant outcomes in a cohort of pregnant women in Nigeria.
Detection of anti-premembrane antibody as a specific marker of four flavivirus serocomplexes and its application to serosurveillance in endemic regions. Emerg Microbes Infect. 2024 Dec; 13(1):2301666.
Audu RA, Okoye RN, Onwuamah CK, Ige FA, Musa AZ, Odunukwe NN, Onwujekwe DI, Ezechi OC, Idigbe EO, Kanki PJ
Potential for false-positive HIV test results using rapid HIV testing algorithms. Afr J Lab Med. 2015; 4(1):178.
Potential for false-positive HIV test results using rapid HIV testing algorithms.
Ebonyi AO, Okpokwu J, Rawizza H, Chebu P, Chaplin B, Hamel D, Oguche S, Agbaji OO, Sagay AS, Kanki PJ, Imade GE
Pretreatment and Acquired Drug Resistance in Children With Human Immunodeficiency Virus Type 1 in Jos, Nigeria. Open Forum Infect Dis. 2024 Mar; 11(3):ofae092.
Pretreatment and Acquired Drug Resistance in Children With Human Immunodeficiency Virus Type 1 in Jos, Nigeria.
Kanki PJ, Hamel DJ, Riedel S, Dutta S, Cheng A, Chang CA, Arnaout R, Kirby JE
Diagnostic microbiology and infectious disease
SARS-CoV-2 live virus culture and sample freeze-thaw stability. Diagn Microbiol Infect Dis. 2024 Jul; 109(3):116282.
SARS-CoV-2 live virus culture and sample freeze-thaw stability.
On Partial Identification of the Natural Indirect Effect. J Causal Inference. 2017 Sep; 5(2).
On Partial Identification of the Natural Indirect Effect.
Young CM, Chang CA, Sagay AS, Imade G, Ogunsola OO, Okonkwo P, Kanki PJ
Antiretroviral therapy retention, adherence, and clinical outcomes among postpartum women with HIV in Nigeria. PLoS One. 2024; 19(8):e0302920.
Antiretroviral therapy retention, adherence, and clinical outcomes among postpartum women with HIV in Nigeria.
Akanbi MO, Achenbach CJ, Feinglass J, Taiwo B, Onu A, Pho MT, Agbaji O, Kanki P, Murphy RL
Tuberculosis after one year of combination antiretroviral therapy in Nigeria: a retrospective cohort study. AIDS Res Hum Retroviruses. 2013 Jun; 29(6):931-7.
Tuberculosis after one year of combination antiretroviral therapy in Nigeria: a retrospective cohort study.
Falade CO, Adesina-Adewole B, Dada-Adegbola HO, Ajayi IO, Akinyemi JO, Ademowo OG, Adewole IF, Kanki P
Evaluation of Paracheck-Pf(TM) rapid malaria diagnostic test for the diagnosis of malaria among HIV-positive patients in Ibadan, south-western Nigeria. Pathog Glob Health. 2013 Mar; 107(2):69-77.
Evaluation of Paracheck-Pf(TM) rapid malaria diagnostic test for the diagnosis of malaria among HIV-positive patients in Ibadan, south-western Nigeria.
Dinic L, Idigbe OE, Meloni S, Rawizza H, Akande P, Eisen G, Onwujekwe D, Agbaji O, Ani A, Kanki PJ
Sputum smear concentration may misidentify acid-fast bacilli as Mycobacterium tuberculosis in HIV-infected patients. J Acquir Immune Defic Syndr. 2013 Jun 01; 63(2):168-77.
Sputum smear concentration may misidentify acid-fast bacilli as Mycobacterium tuberculosis in HIV-infected patients.
Tang MW, Rhee SY, Bertagnolio S, Ford N, Holmes S, Sigaloff KC, Hamers RL, de Wit TF, Fleury HJ, Kanki PJ, Ruxrungtham K, Hawkins CA, Wallis CL, Stevens W, van Zyl GU, Manosuthi W, Hosseinipour MC, Ngo-Giang-Huong N, Belec L, Peeters M, Aghokeng A, Bunupuradah T, Burda S, Cane P, Cappelli G, Charpentier C, Dagnra AY, Deshpande AK, El-Katib Z, Eshleman SH, Fokam J, Gody JC, Katzenstein D, Koyalta DD, Kumwenda JJ, Lallemant M, Lynen L, Marconi VC, Margot NA, Moussa S, Ndung'u T, Nyambi PN, Orrell C, Schapiro JM, Schuurman R, Sirivichayakul S, Smith D, Zolfo M, Jordan MR, Shafer RW
Nucleoside reverse transcriptase inhibitor resistance mutations associated with first-line stavudine-containing antiretroviral therapy: programmatic implications for countries phasing out stavudine. J Infect Dis. 2013 Jun 15; 207 Suppl 2:S70-7.
Nucleoside reverse transcriptase inhibitor resistance mutations associated with first-line stavudine-containing antiretroviral therapy: programmatic implications for countries phasing out stavudine.
Rawizza HE, Chaplin B, Meloni ST, Darin KM, Olaitan O, Scarsi KK, Onwuamah CK, Audu RA, Chebu PR, Imade GE, Okonkwo P, Kanki PJ
Accumulation of protease mutations among patients failing second-line antiretroviral therapy and response to salvage therapy in Nigeria. PLoS One. 2013; 8(9):e73582.
Accumulation of protease mutations among patients failing second-line antiretroviral therapy and response to salvage therapy in Nigeria.
Afolaranmi TO, Chaplin B, Zoakah AI, Kanki PJ
HIV-related stigma among young men who have sex with men in HIV care in Plateau State Nigeria. Front Public Health. 2025; 13:1473369.
HIV-related stigma among young men who have sex with men in HIV care in Plateau State Nigeria.
Herrera BB, Chaplin B, MBoup S, Abdullahi A, He M, Fisher SM, Akanmu S, Chang CA, Hamel DJ, Gupta RK, Kanki PJ
Pre-pandemic cross-reactive antibody and cellular responses against SARS-CoV-2 among female sex workers in Dakar, Senegal. Front Public Health. 2025; 13:1522733.
Pre-pandemic cross-reactive antibody and cellular responses against SARS-CoV-2 among female sex workers in Dakar, Senegal.
Musa J, Taiwo B, Achenbach C, Olugbenga S, Berzins B, Sagay AS, Idoko JA, Kanki PJ, Murphy RL
High-risk human papillomavirus among HIV-infected women with normal cervical cytology: a pilot study in Jos, Nigeria. Arch Gynecol Obstet. 2013 Dec; 288(6):1365-70.
High-risk human papillomavirus among HIV-infected women with normal cervical cytology: a pilot study in Jos, Nigeria.
Al Naimi A, Chang C, Rawizza H, Olaifa O, Ogunsola O, Okonkwo P, Kanki P
Patterns of peri-gestational weight change among women living with HIV in Nigeria receiving dolutegravir compared to alternative antiretroviral regimens: a retrospective cohort study. AIDS Res Ther. 2025 Mar 24; 22(1):38.
Patterns of peri-gestational weight change among women living with HIV in Nigeria receiving dolutegravir compared to alternative antiretroviral regimens: a retrospective cohort study.
Imade GE, Sagay AS, Chaplin B, Chebu P, Musa J, Okpokwu J, Hamel DJ, Pam IC, Agbaji O, Samuels J, Meloni S, Sankale JL, Okonkwo P, Kanki P
Short communication: Transmitted HIV drug resistance in antiretroviral-naive pregnant women in north central Nigeria. AIDS Res Hum Retroviruses. 2014 Feb; 30(2):127-33.
Short communication: Transmitted HIV drug resistance in antiretroviral-naive pregnant women in north central Nigeria.
The protective effect of HIV-2 infection: implications for understanding HIV-1 immunity. AIDS. 2014 Apr 24; 28(7):1065-7.
The protective effect of HIV-2 infection: implications for understanding HIV-1 immunity.
Imade GE, Sagay AS, Musa J, Ocheke AN, Adeniyi DS, Idighri M, Powl R, Sendeht A, Ogwuche JP, Elujoba M, Egbodo CO, Oyebode T, Daru PH, Agbaji O, Pam IC, Meloni ST, Okonkwo P, Kanki PJ
Declining rate of infection with maternal human immunodeficiency virus at delivery units in north-central Nigeria. Afr J Reprod Health. 2013 Dec; 17(4 Spec No):138-45.
Declining rate of infection with maternal human immunodeficiency virus at delivery units in north-central Nigeria.
The journal of obstetrics and gynaecology research
The effect of dolutegravir on obstetrical outcomes among women living with HIV: A retrospective cohort study. J Obstet Gynaecol Res. 2025 Jun; 51(6):e16349.
The effect of dolutegravir on obstetrical outcomes among women living with HIV: A retrospective cohort study.
Ige OO, Yilgwan CS, Sagay AS, Kanki P, Bode-Thomas F
Congenital heart disease in neonates with external congenital anomalies in Jos, Nigeria. J Med Trop. 2020 Jan-Jun; 22(1):19-25.
Congenital heart disease in neonates with external congenital anomalies in Jos, Nigeria.
Kim T, Herrera BB, Chaplin B, Naito-Keoho K, Ogwuche J, Sagay AS, Chang CA, Hamel DJ, Wang WK, Kanki PJ
Preexisting yellow fever virus and West Nile virus immunity and pregnancy outcomes in a Nigerian cohort with endemic orthoflavivirus exposure. Emerg Microbes Infect. 2025 Dec; 14(1):2544720.
Preexisting yellow fever virus and West Nile virus immunity and pregnancy outcomes in a Nigerian cohort with endemic orthoflavivirus exposure.
Okonkwo P, Sagay AS, Agaba PA, Yohanna S, Agbaji OO, Imade GE, Banigbe B, Adeola J, Oyebode TA, Idoko JA, Kanki PJ
Treatment outcomes in a decentralized antiretroviral therapy program: a comparison of two levels of care in north central Nigeria. AIDS Res Treat. 2014; 2014:560623.
Treatment outcomes in a decentralized antiretroviral therapy program: a comparison of two levels of care in north central Nigeria.
Olaleye DO, Odaibo GN, Carney P, Agbaji O, Sagay AS, Muktar H, Akinyinka OO, Omigbodun AO, Ogunniyi A, Gashau W, Akanmu S, Ogunsola F, Chukwuka C, Okonkwo PI, Meloni ST, Adewole I, Kanki PJ, Murphy RL
Academic medicine : journal of the Association of American Medical Colleges
Enhancement of health research capacity in Nigeria through north-south and in-country partnerships. Acad Med. 2014 Aug; 89(8 Suppl):S93-7.
Enhancement of health research capacity in Nigeria through north-south and in-country partnerships.
Chaplin B, Meloni S, Eisen G, Jolayemi T, Banigbe B, Adeola J, Wen C, Reyes Nieva H, Chang C, Okonkwo P, Kanki P
International journal of medical informatics
Scale-up of networked HIV treatment in Nigeria: creation of an integrated electronic medical records system. Int J Med Inform. 2015 Jan; 84(1):58-68.
Scale-up of networked HIV treatment in Nigeria: creation of an integrated electronic medical records system.
Musa J, Achenbach C, Taiwo B, Berzins B, Silas O, Daru PH, Agbaji O, Imade G, Sagay AS, Idoko JA, Kanki PJ, Murphy RL
High-risk human papilloma virus and cervical abnormalities in HIV-infected women with normal cervical cytology. Infect Agent Cancer. 2014; 9(1):36.
High-risk human papilloma virus and cervical abnormalities in HIV-infected women with normal cervical cytology.
Meloni ST, Chaplin B, Chang C, Rawizza H, Okonkwo P, Kanki PJ
Patterns of Adherence and Loss to Follow-Up in Pediatric Patients on ART in Nigeria. Curr HIV Res. 2015; 13(3):210-8.
Patterns of Adherence and Loss to Follow-Up in Pediatric Patients on ART in Nigeria.
Sagay AS, Ebonyi AO, Meloni ST, Musa J, Oguche S, Ekwempu CC, Oyebode T, Ejeliogu E, Imade GE, Agbaji OO, Okonkwo P, Kanki PJ
Mother-to-Child Transmission Outcomes of HIV-Exposed Infants Followed Up in Jos North-Central Nigeria. Curr HIV Res. 2015; 13(3):193-200.
Mother-to-Child Transmission Outcomes of HIV-Exposed Infants Followed Up in Jos North-Central Nigeria.
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