RNA granules: post-transcriptional and epigenetic modulators of gene expression. Nat Rev Mol Cell Biol. 2009 Jun; 10(6):430-6.
RNA granules: post-transcriptional and epigenetic modulators of gene expression.
Emara MM, Ivanov P, Hickman T, Dawra N, Tisdale S, Kedersha N, Hu GF, Anderson P
Angiogenin-induced tRNA-derived stress-induced RNAs promote stress-induced stress granule assembly. J Biol Chem. 2010 Apr 02; 285(14):10959-68.
Angiogenin-induced tRNA-derived stress-induced RNAs promote stress-induced stress granule assembly.
Izumi Y, Ida H, Huang M, Iwanaga N, Tanaka F, Aratake K, Arima K, Tamai M, Kamachi M, Nakamura H, Origuchi T, Kawakami A, Anderson P, Eguchi K
The Journal of laboratory and clinical medicine
Characterization of peripheral natural killer cells in primary Sjögren's syndrome: impaired NK cell activity and low NK cell number. J Lab Clin Med. 2006 May; 147(5):242-9.
Characterization of peripheral natural killer cells in primary Sjögren's syndrome: impaired NK cell activity and low NK cell number.
The Role of RNA in Biological Phase Separations. J Mol Biol. 2018 11 02; 430(23):4685-4701.
The Role of RNA in Biological Phase Separations.
Visibly stressed: the role of eIF2, TIA-1, and stress granules in protein translation. Cell Stress Chaperones. 2002 Apr; 7(2):213-21.
Visibly stressed: the role of eIF2, TIA-1, and stress granules in protein translation.
Ghisolfi L, Dutt S, McConkey ME, Ebert BL, Anderson P
Biochemical and biophysical research communications
Stress granules contribute to a-globin homeostasis in differentiating erythroid cells. Biochem Biophys Res Commun. 2012 Apr 20; 420(4):768-74.
Stress granules contribute to a-globin homeostasis in differentiating erythroid cells.
Phillips K, Kedersha N, Shen L, Blackshear PJ, Anderson P
Proceedings of the National Academy of Sciences of the United States of America
Arthritis suppressor genes TIA-1 and TTP dampen the expression of tumor necrosis factor alpha, cyclooxygenase 2, and inflammatory arthritis. Proc Natl Acad Sci U S A. 2004 Feb 17; 101(7):2011-6.
Arthritis suppressor genes TIA-1 and TTP dampen the expression of tumor necrosis factor alpha, cyclooxygenase 2, and inflammatory arthritis.
Joguparthi V, Breen P, Compadre C, Zhou X, Gann L, Hiller FC, Anderson P
Journal of aerosol medicine : the official journal of the International Society for Aerosols in Medicine
Effect of propellant on the pharmacokinetics and pharmacodynamics of inhaled albuterol in asthmatic subjects. J Aerosol Med. 2003; 16(1):47-53.
Effect of propellant on the pharmacokinetics and pharmacodynamics of inhaled albuterol in asthmatic subjects.
Simarro M, Mauger D, Rhee K, Pujana MA, Kedersha NL, Yamasaki S, Cusick ME, Vidal M, Garcia-Blanco MA, Anderson P
Fas-activated serine/threonine phosphoprotein (FAST) is a regulator of alternative splicing. Proc Natl Acad Sci U S A. 2007 Jul 03; 104(27):11370-5.
Fas-activated serine/threonine phosphoprotein (FAST) is a regulator of alternative splicing.
Cold Spring Harbor perspectives in biology
Stress Granules and Processing Bodies in Translational Control. Cold Spring Harb Perspect Biol. 2019 05 01; 11(5).
Stress Granules and Processing Bodies in Translational Control.
Reprogramming mRNA translation during stress. Curr Opin Cell Biol. 2008 Apr; 20(2):222-6.
Reprogramming mRNA translation during stress.
Ohn T, Kedersha N, Hickman T, Tisdale S, Anderson P
A functional RNAi screen links O-GlcNAc modification of ribosomal proteins to stress granule and processing body assembly. Nat Cell Biol. 2008 Oct; 10(10):1224-31.
A functional RNAi screen links O-GlcNAc modification of ribosomal proteins to stress granule and processing body assembly.
Angiogenin cleaves tRNA and promotes stress-induced translational repression. J Cell Biol. 2009 Apr 06; 185(1):35-42.
Angiogenin cleaves tRNA and promotes stress-induced translational repression.
Stress granules. Curr Biol. 2009 May 26; 19(10):R397-8.
Dolovich MB, Ahrens RC, Hess DR, Anderson P, Dhand R, Rau JL, Smaldone GC, Guyatt G
Device selection and outcomes of aerosol therapy: Evidence-based guidelines: American College of Chest Physicians/American College of Asthma, Allergy, and Immunology. Chest. 2005 Jan; 127(1):335-71.
Device selection and outcomes of aerosol therapy: Evidence-based guidelines: American College of Chest Physicians/American College of Asthma, Allergy, and Immunology.
Li CH, Ohn T, Ivanov P, Tisdale S, Anderson P
eIF5A promotes translation elongation, polysome disassembly and stress granule assembly. PLoS One. 2010 Apr 01; 5(4):e9942.
eIF5A promotes translation elongation, polysome disassembly and stress granule assembly.
Adachi R, Krilis SA, Nigrovic PA, Hamilton MJ, Chung K, Thakurdas SM, Boyce JA, Anderson P, Stevens RL
Ras guanine nucleotide-releasing protein-4 (RasGRP4) involvement in experimental arthritis and colitis. J Biol Chem. 2012 Jun 08; 287(24):20047-55.
Ras guanine nucleotide-releasing protein-4 (RasGRP4) involvement in experimental arthritis and colitis.
Aulas A, Lyons SM, Fay MM, Anderson P, Ivanov P
Nitric oxide triggers the assembly of "type II" stress granules linked to decreased cell viability. Cell Death Dis. 2018 11 13; 9(11):1129.
Nitric oxide triggers the assembly of "type II" stress granules linked to decreased cell viability.
Iseni F, Garcin D, Nishio M, Kedersha N, Anderson P, Kolakofsky D
Sendai virus trailer RNA binds TIAR, a cellular protein involved in virus-induced apoptosis. EMBO J. 2002 Oct 01; 21(19):5141-50.
Sendai virus trailer RNA binds TIAR, a cellular protein involved in virus-induced apoptosis.
Sun L, Stoecklin G, Van Way S, Hinkovska-Galcheva V, Guo RF, Anderson P, Shanley TP
Tristetraprolin (TTP)-14-3-3 complex formation protects TTP from dephosphorylation by protein phosphatase 2a and stabilizes tumor necrosis factor-alpha mRNA. J Biol Chem. 2007 Feb 09; 282(6):3766-77.
Tristetraprolin (TTP)-14-3-3 complex formation protects TTP from dephosphorylation by protein phosphatase 2a and stabilizes tumor necrosis factor-alpha mRNA.
Post-transcriptional regulons coordinate the initiation and resolution of inflammation. Nat Rev Immunol. 2010 Jan; 10(1):24-35.
Post-transcriptional regulons coordinate the initiation and resolution of inflammation.
Bono CM, Schoenfeld A, Gupta G, Harrop JS, Anderson P, Patel AA, Dimar J, Aarabi B, Dailey A, Vaccaro AR, Gahr R, Shaffrey C, Anderson DG, Rampersaud R
Reliability and reproducibility of subaxial cervical injury description system: a standardized nomenclature schema. Spine (Phila Pa 1976). 2011 Aug 01; 36(17):E1140-4.
Reliability and reproducibility of subaxial cervical injury description system: a standardized nomenclature schema.
ARE-mRNA degradation requires the 5'-3' decay pathway. EMBO Rep. 2006 Jan; 7(1):72-7.
ARE-mRNA degradation requires the 5'-3' decay pathway.
Mammalian stress granules and processing bodies. Methods Enzymol. 2007; 431:61-81.
Mammalian stress granules and processing bodies.
Emara MM, Fujimura K, Sciaranghella D, Ivanova V, Ivanov P, Anderson P
Hydrogen peroxide induces stress granule formation independent of eIF2a phosphorylation. Biochem Biophys Res Commun. 2012 Jul 13; 423(4):763-9.
Hydrogen peroxide induces stress granule formation independent of eIF2a phosphorylation.
Rayman JB, Hijazi J, Li X, Kedersha N, Anderson PJ, Kandel ER
Genetic Perturbation of TIA1 Reveals a Physiological Role in Fear Memory. Cell Rep. 2019 03 12; 26(11):2970-2983.e4.
Genetic Perturbation of TIA1 Reveals a Physiological Role in Fear Memory.
Panas MD, Kedersha N, Schulte T, Branca RM, Ivanov P, Anderson P
Phosphorylation of G3BP1-S149 does not influence stress granule assembly. J Cell Biol. 2019 Jul 01; 218(7):2425-2432.
Phosphorylation of G3BP1-S149 does not influence stress granule assembly.
Timothy P. and Keli B. Walbert Professor of Medicine in the Field of Rheumatology
James Stillman Professor of Developmental Biology
Abramson SB, Anderson PJ, Buyon JP, Cronstein BN, Pederson T, Philips MR, Serhan CN
A tribute to Gerald Weissmann (1930-2019).
Kedersha N, Panas MD, Achorn CA, Lyons S, Tisdale S, Hickman T, Thomas M, Lieberman J, McInerney GM, Ivanov P, Anderson P
Correction: G3BP-Caprin1-USP10 complexes mediate stress granule condensation and associate with 40S subunits. J Cell Biol. 2020 Jan 06; 219(1).
Correction: G3BP-Caprin1-USP10 complexes mediate stress granule condensation and associate with 40S subunits.
Akiyama Y, Kharel P, Abe T, Anderson P, Ivanov P
Isolation and initial structure-functional characterization of endogenous tRNA-derived stress-induced RNAs. RNA Biol. 2020 08; 17(8):1116-1124.
Isolation and initial structure-functional characterization of endogenous tRNA-derived stress-induced RNAs.
Chang WC, Abe R, Anderson P, Anderson W, Ardern-Jones MR, Beachkofsky TM, Bellón T, Biala AK, Bouchard C, Cavalleri GL, Chapman N, Chodosh J, Choi HK, Cibotti RR, Divito SJ, Dewar K, Dehaeck U, Etminan M, Forbes D, Fuchs E, Goldman JL, Holmes JH, Hope EA, Hung SI, Hsieh CL, Iovieno A, Jagdeo J, Kim MK, Koelle DM, Lacouture ME, Le Pallec S, Lehloenya RJ, Lim R, Lowe A, McCawley J, McCawley J, Micheletti RG, Mockenhaupt M, Niemeyer K, Norcross MA, Oboh D, Olteanu C, Pasieka HB, Peter J, Pirmohamed M, Rieder M, Saeed HN, Shear NH, Shieh C, Straus S, Sukasem C, Sung C, Trubiano JA, Tsou SY, Ueta M, Volpi S, Wan C, Wang H, Wang ZQ, Weintraub J, Whale C, Wheatley LM, Whyte-Croasdaile S, Williams KB, Wright G, Yeung SN, Zhou L, Chung WH, Phillips EJ, Carleton BC
SJS/TEN 2019: From science to translation. J Dermatol Sci. 2020 Apr; 98(1):2-12.
SJS/TEN 2019: From science to translation.
Smith JA, Curry EG, Blue RE, Roden C, Dundon SER, Rodríguez-Vargas A, Jordan DC, Chen X, Lyons SM, Crutchley J, Anderson P, Horb ME, Gladfelter AS, Giudice J
FXR1 splicing is important for muscle development and biomolecular condensates in muscle cells. J Cell Biol. 2020 04 06; 219(4).
FXR1 splicing is important for muscle development and biomolecular condensates in muscle cells.
Sanders DW, Kedersha N, Lee DSW, Strom AR, Drake V, Riback JA, Bracha D, Eeftens JM, Iwanicki A, Wang A, Wei MT, Whitney G, Lyons SM, Anderson P, Jacobs WM, Ivanov P, Brangwynne CP
Competing Protein-RNA Interaction Networks Control Multiphase Intracellular Organization. Cell. 2020 04 16; 181(2):306-324.e28.
Competing Protein-RNA Interaction Networks Control Multiphase Intracellular Organization.
Lyons SM, Kharel P, Akiyama Y, Ojha S, Dave D, Tsvetkov V, Merrick W, Ivanov P, Anderson P
eIF4G has intrinsic G-quadruplex binding activity that is required for tiRNA function. Nucleic Acids Res. 2020 06 19; 48(11):6223-6233.
eIF4G has intrinsic G-quadruplex binding activity that is required for tiRNA function.
Mineo M, Lyons SM, Zdioruk M, von Spreckelsen N, Ferrer-Luna R, Ito H, Alayo QA, Kharel P, Giantini Larsen A, Fan WY, Auduong S, Grauwet K, Passaro C, Khalsa JK, Shah K, Reardon DA, Ligon KL, Beroukhim R, Nakashima H, Ivanov P, Anderson PJ, Lawler SE, Chiocca EA
Tumor Interferon Signaling Is Regulated by a lncRNA INCR1 Transcribed from the PD-L1 Locus. Mol Cell. 2020 06 18; 78(6):1207-1223.e8.
Tumor Interferon Signaling Is Regulated by a lncRNA INCR1 Transcribed from the PD-L1 Locus.
TOP mRNPs: Molecular Mechanisms and Principles of Regulation. Biomolecules. 2020 06 27; 10(7).
TOP mRNPs: Molecular Mechanisms and Principles of Regulation.
Riggs CL, Kedersha N, Ivanov P, Anderson P
Mammalian stress granules and P bodies at a glance. J Cell Sci. 2020 09 01; 133(16).
Mammalian stress granules and P bodies at a glance.
Hofmann S, Kedersha N, Anderson P, Ivanov P
Biochimica et biophysica acta. Molecular cell research
Molecular mechanisms of stress granule assembly and disassembly. Biochim Biophys Acta Mol Cell Res. 2021 01; 1868(1):118876.
Molecular mechanisms of stress granule assembly and disassembly.
Marmor-Kollet H, Siany A, Kedersha N, Knafo N, Rivkin N, Danino YM, Moens TG, Olender T, Sheban D, Cohen N, Dadosh T, Addadi Y, Ravid R, Eitan C, Toth Cohen B, Hofmann S, Riggs CL, Advani VM, Higginbottom A, Cooper-Knock J, Hanna JH, Merbl Y, Van Den Bosch L, Anderson P, Ivanov P, Geiger T, Hornstein E
Spatiotemporal Proteomic Analysis of Stress Granule Disassembly Using APEX Reveals Regulation by SUMOylation and Links to ALS Pathogenesis. Mol Cell. 2020 12 03; 80(5):876-891.e6.
Spatiotemporal Proteomic Analysis of Stress Granule Disassembly Using APEX Reveals Regulation by SUMOylation and Links to ALS Pathogenesis.
Fay MM, Columbo D, Cotter C, Friend C, Henry S, Hoppe M, Karabelas P, Lamy C, Lawell M, Monteith S, Noyes C, Salerno P, Wu J, Zhang HM, Anderson PJ, Kedersha N, Ivanov P, Farny NG
Bisphenol A promotes stress granule assembly and modulates the integrated stress response. Biol Open. 2021 01 10; 10(1).
Bisphenol A promotes stress granule assembly and modulates the integrated stress response.
Schnell HM, Jochem M, Micoogullari Y, Riggs CL, Ivanov P, Welsch H, Ravindran R, Anderson P, Robinson LC, Tatchell K, Hanna J
Reg1 and Snf1 regulate stress-induced relocalization of protein phosphatase-1 to cytoplasmic granules. FEBS J. 2021 08; 288(16):4833-4848.
Reg1 and Snf1 regulate stress-induced relocalization of protein phosphatase-1 to cytoplasmic granules.
Kosmas K, Filippakis H, Khabibullin D, Turkiewicz M, Lam HC, Yu J, Kedersha NL, Anderson PJ, Henske EP
TSC2 Interacts with HDLBP/Vigilin and Regulates Stress Granule Formation. Mol Cancer Res. 2021 08; 19(8):1389-1397.
TSC2 Interacts with HDLBP/Vigilin and Regulates Stress Granule Formation.
Therapeutic advances in respiratory disease
Emerging therapies in cystic fibrosis. Ther Adv Respir Dis. 2010 Jun; 4(3):177-85.
International journal of chronic obstructive pulmonary disease
Use of Respimat Soft Mist inhaler in COPD patients. Int J Chron Obstruct Pulmon Dis. 2006; 1(3):251-9.
Use of Respimat Soft Mist inhaler in COPD patients.
Duplication of inferior vena cava: a rare but clinically significant anatomical variation. N Z Med J. 2014 Nov 07; 127(1405):84-6.
Duplication of inferior vena cava: a rare but clinically significant anatomical variation.
Akiyama Y, Tomioka Y, Abe T, Anderson P, Ivanov P
In lysate RNA digestion provides insights into the angiogenin's specificity towards transfer RNAs. RNA Biol. 2021 12; 18(12):2546-2555.
In lysate RNA digestion provides insights into the angiogenin's specificity towards transfer RNAs.
Wen Y, Wang X, Cahya S, Anderson P, Velasquez C, Torres C, Ferrante A, Kaliyaperumal A
Comparability study of monocyte derived dendritic cells, primary monocytes, and THP1 cells for innate immune responses. J Immunol Methods. 2021 11; 498:113147.
Comparability study of monocyte derived dendritic cells, primary monocytes, and THP1 cells for innate immune responses.
Corrigendum to 'SJS/TEN 2019: From science to translation' [J. Dermatol. Sci. 98/1 (2020) 2-12]. J Dermatol Sci. 2021 Nov; 104(2):146-147.
Corrigendum to 'SJS/TEN 2019: From science to translation' [J. Dermatol. Sci. 98/1 (2020) 2-12].
Szaflarski W, Lesniczak-Staszak M, Sowinski M, Ojha S, Aulas A, Dave D, Malla S, Anderson P, Ivanov P, Lyons SM
Early rRNA processing is a stress-dependent regulatory event whose inhibition maintains nucleolar integrity. Nucleic Acids Res. 2022 01 25; 50(2):1033-1051.
Early rRNA processing is a stress-dependent regulatory event whose inhibition maintains nucleolar integrity.
Akiyama Y, Lyons SM, Fay MM, Tomioka Y, Abe T, Anderson PJ, Ivanov P
Selective Cleavage at CCA Ends and Anticodon Loops of tRNAs by Stress-Induced RNases. Front Mol Biosci. 2022; 9:791094.
Selective Cleavage at CCA Ends and Anticodon Loops of tRNAs by Stress-Induced RNases.
Research Fellow in Medicine Biochemistry
Kharel P, Fay M, Manasova EV, Anderson PJ, Kurkin AV, Guo JU, Ivanov P
Stress promotes RNA G-quadruplex folding in human cells. Nat Commun. 2023 01 13; 14(1):205.
Stress promotes RNA G-quadruplex folding in human cells.
Schulte T, Panas MD, Han X, Williams L, Kedersha N, Fleck JS, Tan TJC, Dopico XC, Olsson A, Morro AM, Hanke L, Nilvebrant J, Giang KA, Nygren PÅ, Anderson P, Achour A, McInerney GM
Caprin-1 binding to the critical stress granule protein G3BP1 is influenced by pH. Open Biol. 2023 05; 13(5):220369.
Caprin-1 binding to the critical stress granule protein G3BP1 is influenced by pH.
Research Fellow in Otolaryngology Head and Neck Surgery
Academic Dean for Partners HealthCare System
Riggs CL, Kedersha N, Amarsanaa M, Zubair SN, Ivanov P, Anderson P
UBAP2L contributes to formation of P-bodies and modulates their association with stress granules. J Cell Biol. 2024 Oct 07; 223(10).
UBAP2L contributes to formation of P-bodies and modulates their association with stress granules.
CBP80 choreographs the NMD two-step. Mol Cell. 2010 Aug 13; 39(3):317-8.
Post-transcriptional regulatory networks in immunity. Immunol Rev. 2013 May; 253(1):253-72.
Post-transcriptional regulatory networks in immunity.
Saikia M, Krokowski D, Guan BJ, Ivanov P, Parisien M, Hu GF, Anderson P, Pan T, Hatzoglou M
Genome-wide identification and quantitative analysis of cleaved tRNA fragments induced by cellular stress. J Biol Chem. 2012 Dec 14; 287(51):42708-25.
Genome-wide identification and quantitative analysis of cleaved tRNA fragments induced by cellular stress.
bioRxiv : the preprint server for biology
Stress granule formation enables anchorage-independence survival in cancer cells. bioRxiv. 2024 Sep 15.
Stress granule formation enables anchorage-independence survival in cancer cells.
Bhatter N, Advani VM, Takenaka Y, Lyons SM, Akiyama Y, Anderson PJ, Ivanov P
Repurposing tRNA isodecoders for non-canonical functions via tRNA cleavage. bioRxiv. 2024 Sep 04.
Repurposing tRNA isodecoders for non-canonical functions via tRNA cleavage.
Adachi Y, Williams AM, Masuda M, Taketani Y, Anderson PJ, Ivanov P
Chronic stress antagonizes formation of Stress Granules. bioRxiv. 2024 Nov 03.
Chronic stress antagonizes formation of Stress Granules.
Kharel P, Bhatter N, Zubair S, Lyons S, Anderson PJ, Ivanov P
G-quadruplex topologies determine the functional outcome of guanine-rich bioactive oligonucleotides. bioRxiv. 2024 Dec 01.
G-quadruplex topologies determine the functional outcome of guanine-rich bioactive oligonucleotides.
Stress granules and cell signaling: more than just a passing phase? Trends Biochem Sci. 2013 Oct; 38(10):494-506.
Stress granules and cell signaling: more than just a passing phase?
The role of posttranslational modifications in the assembly of stress granules. Wiley Interdiscip Rev RNA. 2010 Nov-Dec; 1(3):486-93.
The role of posttranslational modifications in the assembly of stress granules.
Kamachi M, Le TM, Kim SJ, Geiger ME, Anderson P, Utz PJ
Human autoimmune sera as molecular probes for the identification of an autoantigen kinase signaling pathway. J Exp Med. 2002 Nov 04; 196(9):1213-25.
Human autoimmune sera as molecular probes for the identification of an autoantigen kinase signaling pathway.
Cho C, Hills J, Anderson P, Annaswamy T, Cassidy RC, Craig C, DeMicco R, Easa J, Kreiner S, Mazanec D, O'Toole J, Rappard G, Ravinsky R, Schoenfeld A, Shin J, Whitcomb G, Reitman C
The spine journal : official journal of the North American Spine Society
Appropriate use criteria for osteoporotic compression fractures. Spine J. 2025 Aug; 25(8):1652-1669.
Appropriate use criteria for osteoporotic compression fractures.
Katsanou V, Papadaki O, Milatos S, Blackshear PJ, Anderson P, Kollias G, Kontoyiannis DL
HuR as a negative posttranscriptional modulator in inflammation. Mol Cell. 2005 Sep 16; 19(6):777-89.
HuR as a negative posttranscriptional modulator in inflammation.
Alternative translation initiation in immunity: MAVS learns new tricks. Trends Immunol. 2014 May; 35(5):188-9.
Alternative translation initiation in immunity: MAVS learns new tricks.
Jonker R, Deutz NE, Erbland ML, Anderson PJ, Engelen MP
The American journal of clinical nutrition
Alterations in whole-body arginine metabolism in chronic obstructive pulmonary disease. Am J Clin Nutr. 2016 06; 103(6):1458-64.
Alterations in whole-body arginine metabolism in chronic obstructive pulmonary disease.
Clinical nutrition (Edinburgh, Scotland)
Hydrolyzed casein and whey protein meals comparably stimulate net whole-body protein synthesis in COPD patients with nutritional depletion without an additional effect of leucine co-ingestion. Clin Nutr. 2014 Apr; 33(2):211-20.
Hydrolyzed casein and whey protein meals comparably stimulate net whole-body protein synthesis in COPD patients with nutritional depletion without an additional effect of leucine co-ingestion.
Khaperskyy DA, Emara MM, Johnston BP, Anderson P, Hatchette TF, McCormick C
Influenza a virus host shutoff disables antiviral stress-induced translation arrest. PLoS Pathog. 2014 Jul; 10(7):e1004217.
Influenza a virus host shutoff disables antiviral stress-induced translation arrest.
Adachi Y, Masuda M, Taketani Y, Anderson PJ, Ivanov PV
Chronic stress disrupts the network among stress granules, P-bodies, and motor proteins. bioRxiv. 2026 Jan 11.
Chronic stress disrupts the network among stress granules, P-bodies, and motor proteins.
Chronic stress antagonizes formation of stress granules. iScience. 2026 Jan 16; 29(1):114556.
Chronic stress antagonizes formation of stress granules.
Effectiveness of essential amino acid supplementation in stimulating whole body net protein anabolism is comparable between COPD patients and healthy older adults. Metabolism. 2017 Apr; 69:120-129.
Effectiveness of essential amino acid supplementation in stimulating whole body net protein anabolism is comparable between COPD patients and healthy older adults.
Kharel P, Bhatter N, Zubair S, Lyons SM, Anderson PJ, Ivanov P
G-quadruplex topologies determine the functional outcome of guanine-rich bioactive oligonucleotides. Nucleic Acids Res. 2025 Jun 20; 53(12).
Ivanov P, O'Day E, Emara MM, Wagner G, Lieberman J, Anderson P
G-quadruplex structures contribute to the neuroprotective effects of angiogenin-induced tRNA fragments. Proc Natl Acad Sci U S A. 2014 Dec 23; 111(51):18201-6.
G-quadruplex structures contribute to the neuroprotective effects of angiogenin-induced tRNA fragments.
tRNA fragments in human health and disease. FEBS Lett. 2014 Nov 28; 588(23):4297-304.
tRNA fragments in human health and disease.
Jourdain AA, Koppen M, Rodley CD, Maundrell K, Gueguen N, Reynier P, Guaras AM, Enriquez JA, Anderson P, Simarro M, Martinou JC
A mitochondria-specific isoform of FASTK is present in mitochondrial RNA granules and regulates gene expression and function. Cell Rep. 2015 Feb 24; 10(7):1110-21.
A mitochondria-specific isoform of FASTK is present in mitochondrial RNA granules and regulates gene expression and function.
Stress granules, P-bodies and cancer. Biochim Biophys Acta. 2015 Jul; 1849(7):861-70.
Examining the Role of TIA-1 in the cyclic AMP regulated TNF alpha expression of activated macrophages
Johnson ME, Grassetti AV, Taroni JN, Lyons SM, Schweppe D, Gordon JK, Spiera RF, Lafyatis R, Anderson PJ, Gerber SA, Whitfield ML
Stress granules and RNA processing bodies are novel autoantibody targets in systemic sclerosis. Arthritis Res Ther. 2016 Jan 22; 18:27.
Stress granules and RNA processing bodies are novel autoantibody targets in systemic sclerosis.
Fas-activated Ser/Thr phosphoprotein (FAST) is a eukaryotic initiation factor 4E-binding protein that regulates mRNA stability and cell survival. Translation (Austin). 2013; 1(1):e24047.
Fas-activated Ser/Thr phosphoprotein (FAST) is a eukaryotic initiation factor 4E-binding protein that regulates mRNA stability and cell survival.
G3BP-Caprin1-USP10 complexes mediate stress granule condensation and associate with 40S subunits. J Cell Biol. 2016 Mar 28; 212(7):845-60.
G3BP-Caprin1-USP10 complexes mediate stress granule condensation and associate with 40S subunits.
Simarro M, Chen M, De la Fuente MA, Eiros JM, Orduña A, Anderson P
Deletion of FAST (Fas-activated serine/threonine phosphoprotein) ameliorates immune complex arthritis in mice. Mod Rheumatol. 2016 07; 26(4):630-2.
Deletion of FAST (Fas-activated serine/threonine phosphoprotein) ameliorates immune complex arthritis in mice.
Jayabalan AK, Sanchez A, Park RY, Yoon SP, Kang GY, Baek JH, Anderson P, Kee Y, Ohn T
NEDDylation promotes stress granule assembly. Nat Commun. 2016 07 06; 7:12125.
NEDDylation promotes stress granule assembly.
Lyons SM, Achorn C, Kedersha NL, Anderson PJ, Ivanov P
YB-1 regulates tiRNA-induced Stress Granule formation but not translational repression. Nucleic Acids Res. 2016 Aug 19; 44(14):6949-60.
YB-1 regulates tiRNA-induced Stress Granule formation but not translational repression.
Szaflarski W, Fay MM, Kedersha N, Zabel M, Anderson P, Ivanov P
Vinca alkaloid drugs promote stress-induced translational repression and stress granule formation. Oncotarget. 2016 May 24; 7(21):30307-22.
Vinca alkaloid drugs promote stress-induced translational repression and stress granule formation.
Cellular and Molecular Effectors of Synovitis
Characterization of mammalian stress granules
ROLE OF PSGL 1 IN NATURAL KILLER CELL FUNCTION
Angiogenin-Induced RNA Cleavage in Cancer
FASEB SRC on Post-transcriptional Control of Gene Expression: Mechanisms of mRNA
The role of FAST in immune-mediated inflammatory disease
TNE ROLE OF TIAK IN APOPTOTIC CELL DEATH
Post-transcriptional regulation of TNF-alpha production
Mechanistic insights into mammalian stress granule dynamics. J Cell Biol. 2016 Nov 07; 215(3):313-323.
Mechanistic insights into mammalian stress granule dynamics.
Lyons SM, Fay MM, Akiyama Y, Anderson PJ, Ivanov P
RNA biology of angiogenin: Current state and perspectives. RNA Biol. 2017 02; 14(2):171-178.
RNA biology of angiogenin: Current state and perspectives.
RNA-Seeded Functional Amyloids Balance Growth and Survival. Dev Cell. 2016 10 24; 39(2):131-132.
RNA-Seeded Functional Amyloids Balance Growth and Survival.
Aulas A, Fay MM, Lyons SM, Achorn CA, Kedersha N, Anderson P, Ivanov P
Stress-specific differences in assembly and composition of stress granules and related foci. J Cell Sci. 2017 03 01; 130(5):927-937.
Stress-specific differences in assembly and composition of stress granules and related foci.
The tumor necrosis factor-alpha AU-rich element inhibits the stable association of the 40S ribosomal subunit with RNA transcripts. Biochem Biophys Res Commun. 2005 Aug 12; 333(4):1100-6.
The tumor necrosis factor-alpha AU-rich element inhibits the stable association of the 40S ribosomal subunit with RNA transcripts.
McEwen E, Kedersha N, Song B, Scheuner D, Gilks N, Han A, Chen JJ, Anderson P, Kaufman RJ
Heme-regulated inhibitor kinase-mediated phosphorylation of eukaryotic translation initiation factor 2 inhibits translation, induces stress granule formation, and mediates survival upon arsenite exposure. J Biol Chem. 2005 Apr 29; 280(17):16925-33.
Heme-regulated inhibitor kinase-mediated phosphorylation of eukaryotic translation initiation factor 2 inhibits translation, induces stress granule formation, and mediates survival upon arsenite exposure.
Boeynaems S, Bogaert E, Kovacs D, Konijnenberg A, Timmerman E, Volkov A, Guharoy M, De Decker M, Jaspers T, Ryan VH, Janke AM, Baatsen P, Vercruysse T, Kolaitis RM, Daelemans D, Taylor JP, Kedersha N, Anderson P, Impens F, Sobott F, Schymkowitz J, Rousseau F, Fawzi NL, Robberecht W, Van Damme P, Tompa P, Van Den Bosch L
Phase Separation of C9orf72 Dipeptide Repeats Perturbs Stress Granule Dynamics. Mol Cell. 2017 Mar 16; 65(6):1044-1055.e5.
Phase Separation of C9orf72 Dipeptide Repeats Perturbs Stress Granule Dynamics.
Post-transcriptional control of cytokine production. Nat Immunol. 2008 Apr; 9(4):353-9.
Post-transcriptional control of cytokine production.
Kedersha N, Chen S, Gilks N, Li W, Miller IJ, Stahl J, Anderson P
Evidence that ternary complex (eIF2-GTP-tRNA(i)(Met))-deficient preinitiation complexes are core constituents of mammalian stress granules. Mol Biol Cell. 2002 Jan; 13(1):195-210.
Evidence that ternary complex (eIF2-GTP-tRNA(i)(Met))-deficient preinitiation complexes are core constituents of mammalian stress granules.
Anderson P, Phillips K, Stoecklin G, Kedersha N
Post-transcriptional regulation of proinflammatory proteins. J Leukoc Biol. 2004 Jul; 76(1):42-7.
Post-transcriptional regulation of proinflammatory proteins.
McInerney GM, Kedersha NL, Kaufman RJ, Anderson P, Liljeström P
Importance of eIF2alpha phosphorylation and stress granule assembly in alphavirus translation regulation. Mol Biol Cell. 2005 Aug; 16(8):3753-63.
Importance of eIF2alpha phosphorylation and stress granule assembly in alphavirus translation regulation.
Seminars in respiratory and critical care medicine
Cor pulmonale in cystic fibrosis. Semin Respir Crit Care Med. 2003 Jun; 24(3):323-30.
Geldanamycin inhibits the production of inflammatory cytokines in activated macrophages by reducing the stability and translation of cytokine transcripts. Arthritis Rheum. 2003 Feb; 48(2):541-50.
Geldanamycin inhibits the production of inflammatory cytokines in activated macrophages by reducing the stability and translation of cytokine transcripts.
Tumor necrosis factor inhibitors: clinical implications of their different immunogenicity profiles. Semin Arthritis Rheum. 2005 Apr; 34(5 Suppl1):19-22.
Tumor necrosis factor inhibitors: clinical implications of their different immunogenicity profiles.
Ida H, Nakashima T, Kedersha NL, Yamasaki S, Huang M, Izumi Y, Miyashita T, Origuchi T, Kawakami A, Migita K, Bird PI, Anderson P, Eguchi K
Granzyme B leakage-induced cell death: a new type of activation-induced natural killer cell death. Eur J Immunol. 2003 Dec; 33(12):3284-92.
Granzyme B leakage-induced cell death: a new type of activation-induced natural killer cell death.
Dixon DA, Balch GC, Kedersha N, Anderson P, Zimmerman GA, Beauchamp RD, Prescott SM
Regulation of cyclooxygenase-2 expression by the translational silencer TIA-1. J Exp Med. 2003 Aug 04; 198(3):475-81.
Regulation of cyclooxygenase-2 expression by the translational silencer TIA-1.
Li W, Kedersha N, Chen S, Gilks N, Lee G, Anderson P
FAST is a BCL-X(L)-associated mitochondrial protein. Biochem Biophys Res Commun. 2004 May 21; 318(1):95-102.
FAST is a BCL-X(L)-associated mitochondrial protein.
Gilks N, Kedersha N, Ayodele M, Shen L, Stoecklin G, Dember LM, Anderson P
Stress granule assembly is mediated by prion-like aggregation of TIA-1. Mol Biol Cell. 2004 Dec; 15(12):5383-98.
Stress granule assembly is mediated by prion-like aggregation of TIA-1.
A Place for RNAi. Dev Cell. 2005 Sep; 9(3):311-2.
Stress puts TIA on TOP. Genes Dev. 2011 Oct 15; 25(20):2119-24.
Aulas A, Fay MM, Szaflarski W, Kedersha N, Anderson P, Ivanov P
Journal of visualized experiments : JoVE
Methods to Classify Cytoplasmic Foci as Mammalian Stress Granules. J Vis Exp. 2017 05 12; (123).
Methods to Classify Cytoplasmic Foci as Mammalian Stress Granules.
Stress granules: the Tao of RNA triage. Trends Biochem Sci. 2008 Mar; 33(3):141-50.
FAST is a survival protein that senses mitochondrial stress and modulates TIA-1-regulated changes in protein expression. Mol Cell Biol. 2004 Dec; 24(24):10718-32.
FAST is a survival protein that senses mitochondrial stress and modulates TIA-1-regulated changes in protein expression.
Mechanisms of differential immunogenicity of tumor necrosis factor inhibitors. Curr Rheumatol Rep. 2005 Mar; 7(1):3-9.
Mechanisms of differential immunogenicity of tumor necrosis factor inhibitors.
Dang Y, Kedersha N, Low WK, Romo D, Gorospe M, Kaufman R, Anderson P, Liu JO
Eukaryotic initiation factor 2alpha-independent pathway of stress granule induction by the natural product pateamine A. J Biol Chem. 2006 Oct 27; 281(43):32870-8.
Eukaryotic initiation factor 2alpha-independent pathway of stress granule induction by the natural product pateamine A.
Kedersha N, Tisdale S, Hickman T, Anderson P
Real-time and quantitative imaging of mammalian stress granules and processing bodies. Methods Enzymol. 2008; 448:521-52.
Real-time and quantitative imaging of mammalian stress granules and processing bodies.
Prieto-García A, Zheng D, Adachi R, Xing W, Lane WS, Chung K, Anderson P, Hansbro PM, Castells M, Stevens RL
Mast cell restricted mouse and human tryptase·heparin complexes hinder thrombin-induced coagulation of plasma and the generation of fibrin by proteolytically destroying fibrinogen. J Biol Chem. 2012 Mar 09; 287(11):7834-44.
Mast cell restricted mouse and human tryptase·heparin complexes hinder thrombin-induced coagulation of plasma and the generation of fibrin by proteolytically destroying fibrinogen.
Use of the chloride channel activator lubiprostone for constipation in adults with cystic fibrosis: a case series. Ann Pharmacother. 2010 Mar; 44(3):577-81.
Use of the chloride channel activator lubiprostone for constipation in adults with cystic fibrosis: a case series.
Progress in molecular biology and translational science
Regulation of translation by stress granules and processing bodies. Prog Mol Biol Transl Sci. 2009; 90:155-85.
Regulation of translation by stress granules and processing bodies.
Mechanisms of tiRNA-induced translational control
Ivanov P, Emara MM, Villen J, Gygi SP, Anderson P
Angiogenin-induced tRNA fragments inhibit translation initiation. Mol Cell. 2011 Aug 19; 43(4):613-23.
Angiogenin-induced tRNA fragments inhibit translation initiation.
RNA granules. J Cell Biol. 2006 Mar 13; 172(6):803-8.
Stressful initiations. J Cell Sci. 2002 Aug 15; 115(Pt 16):3227-34.
Stoecklin G, Stubbs T, Kedersha N, Wax S, Rigby WF, Blackwell TK, Anderson P
MK2-induced tristetraprolin:14-3-3 complexes prevent stress granule association and ARE-mRNA decay. EMBO J. 2004 Mar 24; 23(6):1313-24.
MK2-induced tristetraprolin:14-3-3 complexes prevent stress granule association and ARE-mRNA decay.
History of aerosol therapy: liquid nebulization to MDIs to DPIs. Respir Care. 2005 Sep; 50(9):1139-50.
History of aerosol therapy: liquid nebulization to MDIs to DPIs.
Low over-expression of TNFalpha in the mouse heart increases contractile performance via TNFR1. J Cell Biochem. 2008 Sep 01; 105(1):99-107.
Low over-expression of TNFalpha in the mouse heart increases contractile performance via TNFR1.
Karpel JP, Peters JI, Szema AM, Smith B, Anderson PJ
Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology
Differences in physicians' self-reported knowledge of, attitudes toward, and responses to the black box warning on long-acting beta-agonists. Ann Allergy Asthma Immunol. 2009 Oct; 103(4):304-10.
Differences in physicians' self-reported knowledge of, attitudes toward, and responses to the black box warning on long-acting beta-agonists.
Simarro M, Giannattasio G, De la Fuente MA, Benarafa C, Subramanian KK, Ishizawar R, Balestrieri B, Andersson EM, Luo HR, Orduña A, Boyce J, Anderson P
Journal of immunology (Baltimore, Md. : 1950)
Fas-activated serine/threonine phosphoprotein promotes immune-mediated pulmonary inflammation. J Immunol. 2010 May 01; 184(9):5325-32.
Fas-activated serine/threonine phosphoprotein promotes immune-mediated pulmonary inflammation.
Jourdain AA, Popow J, de la Fuente MA, Martinou JC, Anderson P, Simarro M
The FASTK family of proteins: emerging regulators of mitochondrial RNA biology. Nucleic Acids Res. 2017 Nov 02; 45(19):10941-10947.
The FASTK family of proteins: emerging regulators of mitochondrial RNA biology.
Kim HS, Kuwano Y, Zhan M, Pullmann R, Mazan-Mamczarz K, Li H, Kedersha N, Anderson P, Wilce MC, Gorospe M, Wilce JA
Elucidation of a C-rich signature motif in target mRNAs of RNA-binding protein TIAR. Mol Cell Biol. 2007 Oct; 27(19):6806-17.
Elucidation of a C-rich signature motif in target mRNAs of RNA-binding protein TIAR.
Simarro M, Gimenez-Cassina A, Kedersha N, Lazaro JB, Adelmant GO, Marto JA, Rhee K, Tisdale S, Danial N, Benarafa C, Orduña A, Anderson P
Fast kinase domain-containing protein 3 is a mitochondrial protein essential for cellular respiration. Biochem Biophys Res Commun. 2010 Oct 22; 401(3):440-6.
Fast kinase domain-containing protein 3 is a mitochondrial protein essential for cellular respiration.
Simarro M, Giannattasio G, Xing W, Lundequist EM, Stewart S, Stevens RL, Orduña A, Boyce JA, Anderson PJ
The translational repressor T-cell intracellular antigen-1 (TIA-1) is a key modulator of Th2 and Th17 responses driving pulmonary inflammation induced by exposure to house dust mite. Immunol Lett. 2012 Aug 30; 146(1-2):8-14.
The translational repressor T-cell intracellular antigen-1 (TIA-1) is a key modulator of Th2 and Th17 responses driving pulmonary inflammation induced by exposure to house dust mite.
Aerosol therapy: assume nothing and require data. Respir Care. 2003 Nov; 48(11):1016-8.
Aerosol therapy: assume nothing and require data.
Lachke SA, Alkuraya FS, Kneeland SC, Ohn T, Aboukhalil A, Howell GR, Saadi I, Cavallesco R, Yue Y, Tsai AC, Nair KS, Cosma MI, Smith RS, Hodges E, Alfadhli SM, Al-Hajeri A, Shamseldin HE, Behbehani A, Hannon GJ, Bulyk ML, Drack AV, Anderson PJ, John SW, Maas RL
Mutations in the RNA granule component TDRD7 cause cataract and glaucoma. Science. 2011 Mar 25; 331(6024):1571-6.
Mutations in the RNA granule component TDRD7 cause cataract and glaucoma.
Kedersha N, Stoecklin G, Ayodele M, Yacono P, Lykke-Andersen J, Fritzler MJ, Scheuner D, Kaufman RJ, Golan DE, Anderson P
Stress granules and processing bodies are dynamically linked sites of mRNP remodeling. J Cell Biol. 2005 Jun 20; 169(6):871-84.
Stress granules and processing bodies are dynamically linked sites of mRNP remodeling.
Posttranscriptional mechanisms regulating the inflammatory response. Adv Immunol. 2006; 89:1-37.
Posttranscriptional mechanisms regulating the inflammatory response.
Yamasaki S, Stoecklin G, Kedersha N, Simarro M, Anderson P
T-cell intracellular antigen-1 (TIA-1)-induced translational silencing promotes the decay of selected mRNAs. J Biol Chem. 2007 Oct 12; 282(41):30070-7.
T-cell intracellular antigen-1 (TIA-1)-induced translational silencing promotes the decay of selected mRNAs.
Stoecklin G, Tenenbaum SA, Mayo T, Chittur SV, George AD, Baroni TE, Blackshear PJ, Anderson P
Genome-wide analysis identifies interleukin-10 mRNA as target of tristetraprolin. J Biol Chem. 2008 Apr 25; 283(17):11689-99.
Genome-wide analysis identifies interleukin-10 mRNA as target of tristetraprolin.
ALS/FTD-Associated C9ORF72 Repeat RNA Promotes Phase Transitions In Vitro and in Cells. Cell Rep. 2017 Dec 19; 21(12):3573-3584.
ALS/FTD-Associated C9ORF72 Repeat RNA Promotes Phase Transitions In Vitro and in Cells.
On again, off again: the SRC-3 transcriptional coactivator moonlights as a translational corepressor. Mol Cell. 2007 Mar 23; 25(6):796-7.
On again, off again: the SRC-3 transcriptional coactivator moonlights as a translational corepressor.
Selenite targets eIF4E-binding protein-1 to inhibit translation initiation and induce the assembly of non-canonical stress granules. Nucleic Acids Res. 2012 Sep; 40(16):8099-110.
Selenite targets eIF4E-binding protein-1 to inhibit translation initiation and induce the assembly of non-canonical stress granules.