Martin, Thomas
eCommons Login: TRM6
first name: Thomas
last name: Martin
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The murine CCR3 receptor regulates both the role of eosinophils and mast cells in allergen-induced airway inflammation and hyperresponsiveness.
PubMed Identifier: 11830666
author list: Humbles AA, Lu B, Friend DS, Okinaga S, Lora J, Al-Garawi A, Martin TR, Gerard NP, Gerard C
published in: Proceedings of the National Academy of Sciences of the United States of America
information resource reference: The murine CCR3 receptor regulates both the role of eosinophils and mast cells in allergen-induced airway inflammation and hyperresponsiveness. Proc Natl Acad Sci U S A. 2002 Feb 05; 99(3):1479-84.
journal title abbreviation: Proc Natl Acad Sci U S A
publication date: 2002-02-05T00:00:00
year: 2002
type: Academic Article
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Clinically useful spirometry in preschool-aged children: evaluation of the 2007 American Thoracic Society Guidelines.
PubMed Identifier: 20653495
author list: Gaffin JM, Shotola NL, Martin TR, Phipatanakul W
published in: The Journal of asthma : official journal of the Association for the Care of Asthma
information resource reference: Clinically useful spirometry in preschool-aged children: evaluation of the 2007 American Thoracic Society Guidelines. J Asthma. 2010 Sep; 47(7):762-7.
journal title abbreviation: J Asthma
publication date: 2010-09-01T00:00:00
year: 2010
type: Academic Article
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Relationship between cystic fibrosis respiratory tract bacterial communities and age, genotype, antibiotics and Pseudomonas aeruginosa.
PubMed Identifier: 20192960
author list: Klepac-Ceraj V, Lemon KP, Martin TR, Allgaier M, Kembel SW, Knapp AA, Lory S, Brodie EL, Lynch SV, Bohannan BJ, Green JL, Maurer BA, Kolter R
published in: Environmental microbiology
information resource reference: Relationship between cystic fibrosis respiratory tract bacterial communities and age, genotype, antibiotics and Pseudomonas aeruginosa. Environ Microbiol. 2010 May; 12(5):1293-303.
journal title abbreviation: Environ Microbiol
publication date: 2010-02-23T00:00:00
year: 2010
type: Academic Article
type: Article
type: Document
type: Information Resource

Role of mast cells in anaphylaxis. Evidence for the importance of mast cells in the cardiopulmonary alterations and death induced by anti-IgE in mice.
PubMed Identifier: 2784802
author list: Martin TR, Galli SJ, Katona IM, Drazen JM
published in: The Journal of clinical investigation
information resource reference: Role of mast cells in anaphylaxis. Evidence for the importance of mast cells in the cardiopulmonary alterations and death induced by anti-IgE in mice. J Clin Invest. 1989 Apr; 83(4):1375-83.
journal title abbreviation: J Clin Invest
publication date: 1989-04-01T00:00:00
year: 1989
type: Academic Article
type: Article
type: Document
type: Information Resource

Sweat testing infants detected by cystic fibrosis newborn screening.
PubMed Identifier: 16202787
author list: Parad RB, Comeau AM, Dorkin HL, Dovey M, Gerstle R, Martin T, O'Sullivan BP
published in: The Journal of pediatrics
information resource reference: Sweat testing infants detected by cystic fibrosis newborn screening. J Pediatr. 2005 Sep; 147(3 Suppl):S69-72.
journal title abbreviation: J Pediatr
publication date: 2005-09-01T00:00:00
year: 2005
type: Academic Article
type: Article
type: Document
type: Information Resource

Th17 cytokines are critical for respiratory syncytial virus-associated airway hyperreponsiveness through regulation by complement C3a and tachykinins.
PubMed Identifier: 21918196
author list: Bera MM, Lu B, Martin TR, Cui S, Rhein LM, Gerard C, Gerard NP
published in: Journal of immunology (Baltimore, Md. : 1950)
information resource reference: Th17 cytokines are critical for respiratory syncytial virus-associated airway hyperreponsiveness through regulation by complement C3a and tachykinins. J Immunol. 2011 Oct 15; 187(8):4245-55.
journal title abbreviation: J Immunol
publication date: 2011-09-14T00:00:00
year: 2011
type: Academic Article
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Genetic variability in pulmonary physiological, cellular, and antibody responses to antigen in mice.
PubMed Identifier: 10508801
author list: Brewer JP, Kisselgof AB, Martin TR
published in: American journal of respiratory and critical care medicine
information resource reference: Genetic variability in pulmonary physiological, cellular, and antibody responses to antigen in mice. Am J Respir Crit Care Med. 1999 Oct; 160(4):1150-6.
journal title abbreviation: Am J Respir Crit Care Med
publication date: 1999-10-01T00:00:00
year: 1999
type: Academic Article
type: Article
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type: Information Resource

Quantitative locus analysis of airway hyperresponsiveness in A/J and C57BL/6J mice.
PubMed Identifier: 7550342
author list: De Sanctis GT, Merchant M, Beier DR, Dredge RD, Grobholz JK, Martin TR, Lander ES, Drazen JM
published in: Nature genetics
information resource reference: Quantitative locus analysis of airway hyperresponsiveness in A/J and C57BL/6J mice. Nat Genet. 1995 Oct; 11(2):150-4.
journal title abbreviation: Nat Genet
publication date: 1995-10-01T00:00:00
year: 1995
type: Academic Article
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Mast cell activation enhances airway responsiveness to methacholine in the mouse.
PubMed Identifier: 8450046
author list: Martin TR, Takeishi T, Katz HR, Austen KF, Drazen JM, Galli SJ
published in: The Journal of clinical investigation
information resource reference: Mast cell activation enhances airway responsiveness to methacholine in the mouse. J Clin Invest. 1993 Mar; 91(3):1176-82.
journal title abbreviation: J Clin Invest
publication date: 1993-03-01T00:00:00
year: 1993
type: Academic Article
type: Article
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Active anaphylaxis in IgE-deficient mice.
PubMed Identifier: 8047141
author list: Oettgen HC, Martin TR, Wynshaw-Boris A, Deng C, Drazen JM, Leder P
published in: Nature
information resource reference: Active anaphylaxis in IgE-deficient mice. Nature. 1994 Aug 04; 370(6488):367-70.
journal title abbreviation: Nature
publication date: 1994-08-04T00:00:00
year: 1994
type: Academic Article
type: Article
type: Document
type: Information Resource

SLP-76 deficiency impairs signaling via the high-affinity IgE receptor in mast cells.
PubMed Identifier: 10377180
author list: Pivniouk VI, Martin TR, Lu-Kuo JM, Katz HR, Oettgen HC, Geha RS
published in: The Journal of clinical investigation
information resource reference: SLP-76 deficiency impairs signaling via the high-affinity IgE receptor in mast cells. J Clin Invest. 1999 Jun; 103(12):1737-43.
journal title abbreviation: J Clin Invest
publication date: 1999-06-01T00:00:00
year: 1999
type: Academic Article
type: Article
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The trachea and esophagus after repair of esophageal atresia and distal fistula: computed tomographic observations.
PubMed Identifier: 2392361
author list: Griscom NT, Martin TR
published in: Pediatric radiology
information resource reference: The trachea and esophagus after repair of esophageal atresia and distal fistula: computed tomographic observations. Pediatr Radiol. 1990; 20(6):447-50.
journal title abbreviation: Pediatr Radiol
publication date: 1990-01-01T00:00:00
year: 1990
type: Academic Article
type: Article
type: Document
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Relationship between maximal expiratory flows and lung volumes in growing humans.
PubMed Identifier: 3170432
author list: Martin TR, Feldman HA, Fredberg JJ, Castile RG, Mead J, Wohl ME
published in: Journal of applied physiology (Bethesda, Md. : 1985)
information resource reference: Relationship between maximal expiratory flows and lung volumes in growing humans. J Appl Physiol (1985). 1988 Aug; 65(2):822-8.
journal title abbreviation: J Appl Physiol (1985)
publication date: 1988-08-01T00:00:00
year: 1988
type: Academic Article
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Lipopolysaccharides
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Fas Ligand Protein
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Harvard Medical School
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Christiani, David
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Pier, Gerald
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Levy, Bruce
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Priebe, Gregory
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Serhan, Charles
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Liu, Kaifeng
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Person ID: 58006
person in primary position: Research Associate in Pediatrics
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Rosen, Dennis
eCommons Login: DR25
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person in primary position: Assistant Professor of Pediatrics
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Drazen, Jeffrey
eCommons Login: JMD5
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Sawicki, Gregory
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person in primary position: Associate Professor of Pediatrics
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Fishman, Martha
eCommons Login: MPF1
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Dorkin, Henry
eCommons Login: HLD2
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Geha, Raif
eCommons Login: RSG3
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Lieberman, Tami
eCommons Login: TDL7
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Talmor, Daniel
eCommons Login: DT8
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person in primary position: Edward Lowenstein Professor of Anaesthesia
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Gerard, Norma
eCommons Login: NPG1
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person in primary position: Professor of Medicine, Emerita
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Authorship 152755
type: Authorship
author rank in publication: 3
linked author: Martin, Thomas
linked information resource: The role of leukocyte emigration and IL-8 on the development of lipopolysaccharide-induced lung injury in rabbits.

Professor of Medicine (Microbiology and Molecular Genetics)
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position in division: Infectious Disease
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position in organization: Brigham and Women's Hospital

Authorship 1432095
type: Authorship
author rank in publication: 29
linked author: Martin, Thomas
linked information resource: Update on the Features and Measurements of Experimental Acute Lung Injury in Animals: An Official American Thoracic Society Workshop Report.

Update on the Features and Measurements of Experimental Acute Lung Injury in Animals: An Official American Thoracic Society Workshop Report.
PubMed Identifier: 35103557
author list: Kulkarni HS, Lee JS, Bastarache JA, Kuebler WM, Downey GP, Albaiceta GM, Altemeier WA, Artigas A, Bates JHT, Calfee CS, Dela Cruz CS, Dickson RP, Englert JA, Everitt JI, Fessler MB, Gelman AE, Gowdy KM, Groshong SD, Herold S, Homer RJ, Horowitz JC, Hsia CCW, Kurahashi K, Laubach VE, Looney MR, Lucas R, Mangalmurti NS, Manicone AM, Martin TR, Matalon S, Matthay MA, McAuley DF, McGrath-Morrow SA, Mizgerd JP, Montgomery SA, Moore BB, Noël A, Perlman CE, Reilly JP, Schmidt EP, Skerrett SJ, Suber TL, Summers C, Suratt BT, Takata M, Tuder R, Uhlig S, Witzenrath M, Zemans RL, Matute-Bello G
published in: American journal of respiratory cell and molecular biology
information resource reference: Update on the Features and Measurements of Experimental Acute Lung Injury in Animals: An Official American Thoracic Society Workshop Report. Am J Respir Cell Mol Biol. 2022 02; 66(2):e1-e14.
journal title abbreviation: Am J Respir Cell Mol Biol
publication date: 2022-02-01T00:00:00
year: 2022
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 274886
type: Authorship
author rank in publication: 2
linked author: Martin, Thomas
linked information resource: Active anaphylaxis in IgE-deficient mice.

Authorship 291382
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linked author: Martin, Thomas
linked information resource: Th17 cytokines are critical for respiratory syncytial virus-associated airway hyperreponsiveness through regulation by complement C3a and tachykinins.

Authorship 392941
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author rank in publication: 12
linked author: Martin, Thomas
linked information resource: Targeting pan-resistant bacteria with antibodies to a broadly conserved surface polysaccharide expressed during infection.

Member of the Affiliated Faculty of Health Sciences and Technology
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position in organization: Massachusetts Institute of Technology

Authorship 476555
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Authorship 170486
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linked information resource: CD40L, but not CD40, is required for allergen-induced bronchial hyperresponsiveness in mice.

Simon Gelman Professor of Anaesthesia
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Edward Lowenstein Professor of Anaesthesia
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Authorship 512997
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Authorship 24953
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linked information resource: Pulmonary and systemic inflammatory responses in rabbits with gram-negative pneumonia.

Authorship 682720
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linked information resource: Blockade of the Fas/FasL system improves pneumococcal clearance from the lungs without preventing dissemination of bacteria to the spleen.

Authorship 682730
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linked information resource: Inflammatory cells as a source of airspace extracellular superoxide dismutase after pulmonary injury.

Authorship 682379
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linked information resource: Hyporesponsiveness of donor cells to lipopolysaccharide stimulation reduces the severity of experimental idiopathic pneumonia syndrome: potential role for a gut-lung axis of inflammation.

Authorship 682791
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linked information resource: Modulation of lipopolysaccharide-induced gene transcription and promotion of lung injury by mechanical ventilation.

Authorship 683012
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linked information resource: Effects of endotoxin in the lungs of neonatal rats: age-dependent impairment of the inflammatory response.

Authorship 682868
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Authorship 683122
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linked information resource: Recombinant murine interferon-gamma reversibly activates rat alveolar macrophages to kill Legionella pneumophila.

Authorship 682965
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linked information resource: Alveolar macrophage function in rats with severe protein calorie malnutrition. Arachidonic acid metabolism, cytokine release, and antimicrobial activity.

Authorship 682705
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author rank in publication: 9
linked author: Martin, Thomas
linked information resource: Tissue-specific mechanisms control the retention of IL-8 in lungs and skin.

Authorship 682819
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author rank in publication: 7
linked author: Martin, Thomas
linked information resource: Conventional mechanical ventilation of healthy lungs induced pro-inflammatory cytokine gene transcription.

Authorship 686354
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author rank in publication: 12
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linked information resource: The Duffy antigen modifies systemic and local tissue chemokine responses following lipopolysaccharide stimulation.

Authorship 682690
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linked information resource: Enhancement of the endotoxin recognition pathway by ventilation with a large tidal volume in rabbits.

Authorship 683743
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linked information resource: An experimental model of idiopathic pneumonia syndrome after bone marrow transplantation: I. The roles of minor H antigens and endotoxin.

Authorship 683766
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Authorship 683960
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author rank in publication: 14
linked author: Martin, Thomas
linked information resource: The biological activity of FasL in human and mouse lungs is determined by the structure of its stalk region.

Authorship 682412
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author rank in publication: 7
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linked information resource: T-lymphocytes regulate genetically determined airway hyperresponsiveness in mice.

Authorship 682599
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author rank in publication: 10
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linked information resource: TLR-4 pathway mediates the inflammatory response but not bacterial elimination in E. coli pneumonia.

Authorship 684151
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linked information resource: Identification of high and low responders to lipopolysaccharide in normal subjects: an unbiased approach to identify modulators of innate immunity.

Authorship 686398
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linked information resource: Kinetics of chemokine-glycosaminoglycan interactions control neutrophil migration into the airspaces of the lungs.

Authorship 684198
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linked information resource: Lung antibacterial defense mechanisms in infant and adult rats: implications for the pathogenesis of group B streptococcal infections in the neonatal lung.

Authorship 685138
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linked information resource: Direct lung injury by bacteria: clarifying the tools of the trade.

Authorship 686058
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linked information resource: Role of the Fas/FasL system in a model of RSV infection in mechanically ventilated mice.

Authorship 690480
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author rank in publication: 9
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linked information resource: Fas-mediated acute lung injury requires fas expression on nonmyeloid cells of the lung.

Authorship 688283
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linked information resource: Effects of age on the synergistic interactions between lipopolysaccharide and mechanical ventilation in mice.

Authorship 685362
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linked author: Martin, Thomas
linked information resource: Host reactive donor T cells are associated with lung injury after experimental allogeneic bone marrow transplantation.

Authorship 683438
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author rank in publication: 2
linked author: Martin, Thomas
linked information resource: Controlled clinical trial of methylprednisolone in patients with chronic bronchitis and acute respiratory insufficiency.

Authorship 683859
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linked information resource: Impaired clearance of aerosolized Legionella pneumophila in corticosteroid-treated rats: a model of Legionnaires' disease in the compromised host.

Authorship 684913
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author rank in publication: 6
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linked information resource: Mechanical ventilation induces inflammation, lung injury, and extra-pulmonary organ dysfunction in experimental pneumonia.

Authorship 686371
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linked information resource: Effect of Toll-like receptor 4 blockade on pulmonary inflammation caused by mechanical ventilation and bacterial endotoxin.

Authorship 687708
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linked author: Martin, Thomas
linked information resource: Depletion of phagocytes in the reticuloendothelial system causes increased inflammation and mortality in rabbits with Pseudomonas aeruginosa pneumonia.

Authorship 683713
type: Authorship
author rank in publication: 1
linked author: Martin, Thomas
linked information resource: The effect of type-specific polysaccharide capsule on the clearance of group B streptococci from the lungs of infant and adult rats.

Authorship 687808
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author rank in publication: 5
linked author: Martin, Thomas
linked information resource: Phenazine content in the cystic fibrosis respiratory tract negatively correlates with lung function and microbial complexity.

Authorship 683269
type: Authorship
author rank in publication: 6
linked author: Martin, Thomas
linked information resource: Quantitative locus analysis of airway hyperresponsiveness in A/J and C57BL/6J mice.

Authorship 690095
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author rank in publication: 7
linked author: Martin, Thomas
linked information resource: Febrile-range hyperthermia augments lipopolysaccharide-induced lung injury by a mechanism of enhanced alveolar epithelial apoptosis.

Authorship 685499
type: Authorship
author rank in publication: 3
linked author: Martin, Thomas
linked information resource: Animal models of acute lung injury.

Authorship 689313
type: Authorship
author rank in publication: 8
linked author: Martin, Thomas
linked information resource: Essential role of MMP-12 in Fas-induced lung fibrosis.

Mechanical ventilation affects lung function and cytokine production in an experimental model of endotoxemia.
PubMed Identifier: 15681948
author list: Brégeon F, Delpierre S, Chetaille B, Kajikawa O, Martin TR, Autillo-Touati A, Jammes Y, Pugin J
published in: Anesthesiology
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Alveolar macrophage function in rats with severe protein calorie malnutrition. Arachidonic acid metabolism, cytokine release, and antimicrobial activity.
PubMed Identifier: 2104909
author list: Skerrett SJ, Henderson WR, Martin TR
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information resource reference: Alveolar macrophage function in rats with severe protein calorie malnutrition. Arachidonic acid metabolism, cytokine release, and antimicrobial activity. J Immunol. 1990 Feb 01; 144(3):1052-61.
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Blockade of the Fas/FasL system improves pneumococcal clearance from the lungs without preventing dissemination of bacteria to the spleen.
PubMed Identifier: 15655784
author list: Matute-Bello G, Liles WC, Frevert CW, Dhanireddy S, Ballman K, Wong V, Green RR, Song HY, Witcher DR, Jakubowski JA, Martin TR
published in: The Journal of infectious diseases
information resource reference: Blockade of the Fas/FasL system improves pneumococcal clearance from the lungs without preventing dissemination of bacteria to the spleen. J Infect Dis. 2005 Feb 15; 191(4):596-606.
journal title abbreviation: J Infect Dis
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Impaired clearance of aerosolized Legionella pneumophila in corticosteroid-treated rats: a model of Legionnaires' disease in the compromised host.
PubMed Identifier: 2760483
author list: Skerrett SJ, Schmidt RA, Martin TR
published in: The Journal of infectious diseases
information resource reference: Impaired clearance of aerosolized Legionella pneumophila in corticosteroid-treated rats: a model of Legionnaires' disease in the compromised host. J Infect Dis. 1989 Aug; 160(2):261-73.
journal title abbreviation: J Infect Dis
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Effects of age on the synergistic interactions between lipopolysaccharide and mechanical ventilation in mice.
PubMed Identifier: 19901347
author list: Smith LS, Gharib SA, Frevert CW, Martin TR
published in: American journal of respiratory cell and molecular biology
information resource reference: Effects of age on the synergistic interactions between lipopolysaccharide and mechanical ventilation in mice. Am J Respir Cell Mol Biol. 2010 Oct; 43(4):475-86.
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publication date: 2009-11-09T00:00:00
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type: Academic Article
type: Article
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type: Information Resource

The effect of type-specific polysaccharide capsule on the clearance of group B streptococci from the lungs of infant and adult rats.
PubMed Identifier: 1730897
author list: Martin TR, Ruzinski JT, Rubens CE, Chi EY, Wilson CB
published in: The Journal of infectious diseases
information resource reference: The effect of type-specific polysaccharide capsule on the clearance of group B streptococci from the lungs of infant and adult rats. J Infect Dis. 1992 Feb; 165(2):306-14.
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publication date: 1992-02-01T00:00:00
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Role of the Fas/FasL system in a model of RSV infection in mechanically ventilated mice.
PubMed Identifier: 21743025
author list: van den Berg E, van Woensel JB, Bos AP, Bem RA, Altemeier WA, Gill SE, Martin TR, Matute-Bello G
published in: American journal of physiology. Lung cellular and molecular physiology
information resource reference: Role of the Fas/FasL system in a model of RSV infection in mechanically ventilated mice. Am J Physiol Lung Cell Mol Physiol. 2011 Oct; 301(4):L451-60.
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Fas-mediated acute lung injury requires fas expression on nonmyeloid cells of the lung.
PubMed Identifier: 16148156
author list: Matute-Bello G, Lee JS, Liles WC, Frevert CW, Mongovin S, Wong V, Ballman K, Sutlief S, Martin TR
published in: Journal of immunology (Baltimore, Md. : 1950)
information resource reference: Fas-mediated acute lung injury requires fas expression on nonmyeloid cells of the lung. J Immunol. 2005 Sep 15; 175(6):4069-75.
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Phenazine content in the cystic fibrosis respiratory tract negatively correlates with lung function and microbial complexity.
PubMed Identifier: 22865623
author list: Hunter RC, Klepac-Ceraj V, Lorenzi MM, Grotzinger H, Martin TR, Newman DK
published in: American journal of respiratory cell and molecular biology
information resource reference: Phenazine content in the cystic fibrosis respiratory tract negatively correlates with lung function and microbial complexity. Am J Respir Cell Mol Biol. 2012 Dec; 47(6):738-45.
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Enhancement of the endotoxin recognition pathway by ventilation with a large tidal volume in rabbits.
PubMed Identifier: 14633514
author list: Moriyama K, Ishizaka A, Nakamura M, Kubo H, Kotani T, Yamamoto S, Ogawa EN, Kajikawa O, Frevert CW, Kotake Y, Morisaki H, Koh H, Tasaka S, Martin TR, Takeda J
published in: American journal of physiology. Lung cellular and molecular physiology
information resource reference: Enhancement of the endotoxin recognition pathway by ventilation with a large tidal volume in rabbits. Am J Physiol Lung Cell Mol Physiol. 2004 Jun; 286(6):L1114-21.
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The biological activity of FasL in human and mouse lungs is determined by the structure of its stalk region.
PubMed Identifier: 21285513
author list: Herrero R, Kajikawa O, Matute-Bello G, Wang Y, Hagimoto N, Mongovin S, Wong V, Park DR, Brot N, Heinecke JW, Rosen H, Goodman RB, Fu X, Martin TR
published in: The Journal of clinical investigation
information resource reference: The biological activity of FasL in human and mouse lungs is determined by the structure of its stalk region. J Clin Invest. 2011 Mar; 121(3):1174-90.
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Febrile-range hyperthermia augments lipopolysaccharide-induced lung injury by a mechanism of enhanced alveolar epithelial apoptosis.
PubMed Identifier: 20200273
author list: Lipke AB, Matute-Bello G, Herrero R, Kurahashi K, Wong VA, Mongovin SM, Martin TR
published in: Journal of immunology (Baltimore, Md. : 1950)
information resource reference: Febrile-range hyperthermia augments lipopolysaccharide-induced lung injury by a mechanism of enhanced alveolar epithelial apoptosis. J Immunol. 2010 Apr 01; 184(7):3801-13.
journal title abbreviation: J Immunol
publication date: 2010-03-03T00:00:00
year: 2010
type: Academic Article
type: Article
type: Document
type: Information Resource

Lung antibacterial defense mechanisms in infant and adult rats: implications for the pathogenesis of group B streptococcal infections in the neonatal lung.
PubMed Identifier: 3275727
author list: Martin TR, Rubens CE, Wilson CB
published in: The Journal of infectious diseases
information resource reference: Lung antibacterial defense mechanisms in infant and adult rats: implications for the pathogenesis of group B streptococcal infections in the neonatal lung. J Infect Dis. 1988 Jan; 157(1):91-100.
journal title abbreviation: J Infect Dis
publication date: 1988-01-01T00:00:00
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type: Academic Article
type: Article
type: Document
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Mechanical ventilation induces inflammation, lung injury, and extra-pulmonary organ dysfunction in experimental pneumonia.
PubMed Identifier: 16855596
author list: Dhanireddy S, Altemeier WA, Matute-Bello G, O'Mahony DS, Glenny RW, Martin TR, Liles WC
published in: Laboratory investigation; a journal of technical methods and pathology
information resource reference: Mechanical ventilation induces inflammation, lung injury, and extra-pulmonary organ dysfunction in experimental pneumonia. Lab Invest. 2006 Aug; 86(8):790-9.
journal title abbreviation: Lab Invest
publication date: 2006-07-03T00:00:00
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type: Academic Article
type: Article
type: Document
type: Information Resource

Animal models of acute lung injury.
PubMed Identifier: 18621912
author list: Matute-Bello G, Frevert CW, Martin TR
published in: American journal of physiology. Lung cellular and molecular physiology
information resource reference: Animal models of acute lung injury. Am J Physiol Lung Cell Mol Physiol. 2008 Sep; 295(3):L379-99.
journal title abbreviation: Am J Physiol Lung Cell Mol Physiol
publication date: 2008-07-11T00:00:00
year: 2008
type: Academic Article
type: Article
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Inflammatory cells as a source of airspace extracellular superoxide dismutase after pulmonary injury.
PubMed Identifier: 16224105
author list: Tan RJ, Lee JS, Manni ML, Fattman CL, Tobolewski JM, Zheng M, Kolls JK, Martin TR, Oury TD
published in: American journal of respiratory cell and molecular biology
information resource reference: Inflammatory cells as a source of airspace extracellular superoxide dismutase after pulmonary injury. Am J Respir Cell Mol Biol. 2006 Feb; 34(2):226-32.
journal title abbreviation: Am J Respir Cell Mol Biol
publication date: 2005-10-13T00:00:00
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type: Academic Article
type: Article
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Conventional mechanical ventilation of healthy lungs induced pro-inflammatory cytokine gene transcription.
PubMed Identifier: 12161332
author list: Brégeon F, Roch A, Delpierre S, Ghigo E, Autillo-Touati A, Kajikawa O, Martin TR, Pugin J, Portugal H, Auffray JP, Jammes Y
published in: Respiratory physiology & neurobiology
information resource reference: Conventional mechanical ventilation of healthy lungs induced pro-inflammatory cytokine gene transcription. Respir Physiol Neurobiol. 2002 Aug 30; 132(2):191-203.
journal title abbreviation: Respir Physiol Neurobiol
publication date: 2002-08-30T00:00:00
year: 2002
type: Academic Article
type: Article
type: Document
type: Information Resource

Direct lung injury by bacteria: clarifying the tools of the trade.
PubMed Identifier: 15640664
author list: Martin TR
published in: Critical care medicine
information resource reference: Direct lung injury by bacteria: clarifying the tools of the trade. Crit Care Med. 2004 Nov; 32(11):2360-1.
journal title abbreviation: Crit Care Med
publication date: 2004-11-01T00:00:00
year: 2004
type: Academic Article
type: Article
type: Document
type: Information Resource

Effects of endotoxin in the lungs of neonatal rats: age-dependent impairment of the inflammatory response.
PubMed Identifier: 7798654
author list: Martin TR, Ruzinski JT, Wilson CB, Skerrett SJ
published in: The Journal of infectious diseases
information resource reference: Effects of endotoxin in the lungs of neonatal rats: age-dependent impairment of the inflammatory response. J Infect Dis. 1995 Jan; 171(1):134-44.
journal title abbreviation: J Infect Dis
publication date: 1995-01-01T00:00:00
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type: Academic Article
type: Article
type: Document
type: Information Resource

Controlled clinical trial of methylprednisolone in patients with chronic bronchitis and acute respiratory insufficiency.
PubMed Identifier: 6770731
author list: Albert RK, Martin TR, Lewis SW
published in: Annals of internal medicine
information resource reference: Controlled clinical trial of methylprednisolone in patients with chronic bronchitis and acute respiratory insufficiency. Ann Intern Med. 1980 Jun; 92(6):753-8.
journal title abbreviation: Ann Intern Med
publication date: 1980-06-01T00:00:00
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type: Academic Article
type: Article
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Kinetics of chemokine-glycosaminoglycan interactions control neutrophil migration into the airspaces of the lungs.
PubMed Identifier: 20124102
author list: Tanino Y, Coombe DR, Gill SE, Kett WC, Kajikawa O, Proudfoot AE, Wells TN, Parks WC, Wight TN, Martin TR, Frevert CW
published in: Journal of immunology (Baltimore, Md. : 1950)
information resource reference: Kinetics of chemokine-glycosaminoglycan interactions control neutrophil migration into the airspaces of the lungs. J Immunol. 2010 Mar 01; 184(5):2677-85.
journal title abbreviation: J Immunol
publication date: 2010-02-01T00:00:00
year: 2010
type: Academic Article
type: Article
type: Document
type: Information Resource

Effect of Toll-like receptor 4 blockade on pulmonary inflammation caused by mechanical ventilation and bacterial endotoxin.
PubMed Identifier: 18465402
author list: Smith LS, Kajikawa O, Elson G, Wick M, Mongovin S, Kosco-Vilbois M, Martin TR, Frevert CW
published in: Experimental lung research
information resource reference: Effect of Toll-like receptor 4 blockade on pulmonary inflammation caused by mechanical ventilation and bacterial endotoxin. Exp Lung Res. 2008 Jun; 34(5):225-43.
journal title abbreviation: Exp Lung Res
publication date: 2008-06-01T00:00:00
year: 2008
type: Academic Article
type: Article
type: Document
type: Information Resource

Tissue-specific mechanisms control the retention of IL-8 in lungs and skin.
PubMed Identifier: 11907118
author list: Frevert CW, Goodman RB, Kinsella MG, Kajikawa O, Ballman K, Clark-Lewis I, Proudfoot AE, Wells TN, Martin TR
published in: Journal of immunology (Baltimore, Md. : 1950)
information resource reference: Tissue-specific mechanisms control the retention of IL-8 in lungs and skin. J Immunol. 2002 Apr 01; 168(7):3550-6.
journal title abbreviation: J Immunol
publication date: 2002-04-01T00:00:00
year: 2002
type: Academic Article
type: Article
type: Document
type: Information Resource

Recombinant murine interferon-gamma reversibly activates rat alveolar macrophages to kill Legionella pneumophila.
PubMed Identifier: 1431253
author list: Skerrett SJ, Martin TR
published in: The Journal of infectious diseases
information resource reference: Recombinant murine interferon-gamma reversibly activates rat alveolar macrophages to kill Legionella pneumophila. J Infect Dis. 1992 Dec; 166(6):1354-61.
journal title abbreviation: J Infect Dis
publication date: 1992-12-01T00:00:00
year: 1992
type: Academic Article
type: Article
type: Document
type: Information Resource

The Duffy antigen modifies systemic and local tissue chemokine responses following lipopolysaccharide stimulation.
PubMed Identifier: 17114483
author list: Lee JS, Wurfel MM, Matute-Bello G, Frevert CW, Rosengart MR, Ranganathan M, Wong VW, Holden T, Sutlief S, Richmond A, Peiper S, Martin TR
published in: Journal of immunology (Baltimore, Md. : 1950)
information resource reference: The Duffy antigen modifies systemic and local tissue chemokine responses following lipopolysaccharide stimulation. J Immunol. 2006 Dec 01; 177(11):8086-94.
journal title abbreviation: J Immunol
publication date: 2006-12-01T00:00:00
year: 2006
type: Academic Article
type: Article
type: Document
type: Information Resource

Modulation of lipopolysaccharide-induced gene transcription and promotion of lung injury by mechanical ventilation.
PubMed Identifier: 16116230
author list: Altemeier WA, Matute-Bello G, Gharib SA, Glenny RW, Martin TR, Liles WC
published in: Journal of immunology (Baltimore, Md. : 1950)
information resource reference: Modulation of lipopolysaccharide-induced gene transcription and promotion of lung injury by mechanical ventilation. J Immunol. 2005 Sep 01; 175(5):3369-76.
journal title abbreviation: J Immunol
publication date: 2005-09-01T00:00:00
year: 2005
type: Academic Article
type: Article
type: Document
type: Information Resource

Identification of high and low responders to lipopolysaccharide in normal subjects: an unbiased approach to identify modulators of innate immunity.
PubMed Identifier: 16081831
author list: Wurfel MM, Park WY, Radella F, Ruzinski J, Sandstrom A, Strout J, Bumgarner RE, Martin TR
published in: Journal of immunology (Baltimore, Md. : 1950)
information resource reference: Identification of high and low responders to lipopolysaccharide in normal subjects: an unbiased approach to identify modulators of innate immunity. J Immunol. 2005 Aug 15; 175(4):2570-8.
journal title abbreviation: J Immunol
publication date: 2005-08-15T00:00:00
year: 2005
type: Academic Article
type: Article
type: Document
type: Information Resource

Duffy antigen facilitates movement of chemokine across the endothelium in vitro and promotes neutrophil transmigration in vitro and in vivo.
PubMed Identifier: 12734373
author list: Lee JS, Frevert CW, Wurfel MM, Peiper SC, Wong VA, Ballman KK, Ruzinski JT, Rhim JS, Martin TR, Goodman RB
published in: Journal of immunology (Baltimore, Md. : 1950)
information resource reference: Duffy antigen facilitates movement of chemokine across the endothelium in vitro and promotes neutrophil transmigration in vitro and in vivo. J Immunol. 2003 May 15; 170(10):5244-51.
journal title abbreviation: J Immunol
publication date: 2003-05-15T00:00:00
year: 2003
type: Academic Article
type: Article
type: Document
type: Information Resource

TLR-4 pathway mediates the inflammatory response but not bacterial elimination in E. coli pneumonia.
PubMed Identifier: 16024722
author list: Lee JS, Frevert CW, Matute-Bello G, Wurfel MM, Wong VA, Lin SM, Ruzinski J, Mongovin S, Goodman RB, Martin TR
published in: American journal of physiology. Lung cellular and molecular physiology
information resource reference: TLR-4 pathway mediates the inflammatory response but not bacterial elimination in E. coli pneumonia. Am J Physiol Lung Cell Mol Physiol. 2005 Nov; 289(5):L731-8.
journal title abbreviation: Am J Physiol Lung Cell Mol Physiol
publication date: 2005-07-15T00:00:00
year: 2005
type: Academic Article
type: Article
type: Document
type: Information Resource

Essential role of MMP-12 in Fas-induced lung fibrosis.
PubMed Identifier: 17446527
author list: Matute-Bello G, Wurfel MM, Lee JS, Park DR, Frevert CW, Madtes DK, Shapiro SD, Martin TR
published in: American journal of respiratory cell and molecular biology
information resource reference: Essential role of MMP-12 in Fas-induced lung fibrosis. Am J Respir Cell Mol Biol. 2007 Aug; 37(2):210-21.
journal title abbreviation: Am J Respir Cell Mol Biol
publication date: 2007-04-19T00:00:00
year: 2007
type: Academic Article
type: Article
type: Document
type: Information Resource

Professor of Medicine, Emerita
is primary position: true
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position in division: https://connects.catalyst.harvard.edu/Profiles/profile/1229413
sort order: 1
type: Position
HR job title: Professor of Medicine, Emerita
position in organization: Harvard Medical School

Hersey Professor of the Theory and Practice of Physic
is primary position: true
position in department: Medicine
position in division: Pulmonary
sort order: 1
type: Position
HR job title: Hersey Professor of the Theory and Practice of Physic
position in organization: Brigham and Women's Hospital

Authorship 699749
type: Authorship
author rank in publication: 4
linked author: Martin, Thomas
linked information resource: Genetic variation of a bacterial pathogen within individuals with cystic fibrosis provides a record of selective pressures.

Genetic variation of a bacterial pathogen within individuals with cystic fibrosis provides a record of selective pressures.
PubMed Identifier: 24316980
author list: Lieberman TD, Flett KB, Yelin I, Martin TR, McAdam AJ, Priebe GP, Kishony R
published in: Nature genetics
information resource reference: Genetic variation of a bacterial pathogen within individuals with cystic fibrosis provides a record of selective pressures. Nat Genet. 2014 Jan; 46(1):82-7.
journal title abbreviation: Nat Genet
publication date: 2013-12-08T00:00:00
year: 2013
type: Academic Article
type: Article
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type: Information Resource

Authorship 707922
type: Authorship
author rank in publication: 1
linked author: Martin, Thomas
linked information resource: Relationship between maximal expiratory flows and lung volumes in growing humans.

Authorship 707706
type: Authorship
author rank in publication: 2
linked author: Martin, Thomas
linked information resource: The trachea and esophagus after repair of esophageal atresia and distal fistula: computed tomographic observations.

Authorship 715965
type: Authorship
author rank in publication: 13
linked author: Martin, Thomas
linked information resource: Syndecan-4 regulates early neutrophil migration and pulmonary inflammation in response to lipopolysaccharide.

Authorship 717609
type: Authorship
author rank in publication: 8
linked author: Martin, Thomas
linked information resource: The Fas/FasL pathway impairs the alveolar fluid clearance in mouse lungs.

Authorship 716173
type: Authorship
author rank in publication: 3
linked author: Martin, Thomas
linked information resource: Mechanisms of acute respiratory distress syndrome in children and adults: a review and suggestions for future research.

Syndecan-4 regulates early neutrophil migration and pulmonary inflammation in response to lipopolysaccharide.
PubMed Identifier: 22427536
author list: Tanino Y, Chang MY, Wang X, Gill SE, Skerrett S, McGuire JK, Sato S, Nikaido T, Kojima T, Munakata M, Mongovin S, Parks WC, Martin TR, Wight TN, Frevert CW
published in: American journal of respiratory cell and molecular biology
information resource reference: Syndecan-4 regulates early neutrophil migration and pulmonary inflammation in response to lipopolysaccharide. Am J Respir Cell Mol Biol. 2012 Aug; 47(2):196-202.
journal title abbreviation: Am J Respir Cell Mol Biol
publication date: 2012-03-15T00:00:00
year: 2012
type: Academic Article
type: Article
type: Document
type: Information Resource

Mechanisms of acute respiratory distress syndrome in children and adults: a review and suggestions for future research.
PubMed Identifier: 23823199
author list: Smith LS, Zimmerman JJ, Martin TR
published in: Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies
information resource reference: Mechanisms of acute respiratory distress syndrome in children and adults: a review and suggestions for future research. Pediatr Crit Care Med. 2013 Jul; 14(6):631-43.
journal title abbreviation: Pediatr Crit Care Med
publication date: 2013-07-01T00:00:00
year: 2013
type: Academic Article
type: Article
type: Document
type: Information Resource

The Fas/FasL pathway impairs the alveolar fluid clearance in mouse lungs.
PubMed Identifier: 23812636
author list: Herrero R, Tanino M, Smith LS, Kajikawa O, Wong VA, Mongovin S, Matute-Bello G, Martin TR
published in: American journal of physiology. Lung cellular and molecular physiology
information resource reference: The Fas/FasL pathway impairs the alveolar fluid clearance in mouse lungs. Am J Physiol Lung Cell Mol Physiol. 2013 Sep; 305(5):L377-88.
journal title abbreviation: Am J Physiol Lung Cell Mol Physiol
publication date: 2013-06-28T00:00:00
year: 2013
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 265685
type: Authorship
author rank in publication: 10
linked author: Martin, Thomas
linked information resource: Cytokine balance in the lungs of patients with acute respiratory distress syndrome.

Authorship 344520
type: Authorship
author rank in publication: 1
linked author: Martin, Thomas
linked information resource: Pulmonary responses to bronchoconstrictor agonists in the mouse.

Assistant Professor of Pediatrics
is primary position: true
position in department: Pediatrics
position in division: Pulmonary
sort order: 1
type: Position
HR job title: Assistant Professor of Pediatrics
position in organization: Boston Children's Hospital

Parker B. Francis Distinguished Professor of Medicine
is primary position: true
position in department: Medicine
position in division: Pulmonary
sort order: 1
type: Position
HR job title: Parker B. Francis Distinguished Professor of Medicine
position in organization: Brigham and Women's Hospital

Associate Professor of Anaesthesia
is primary position: true
position in department: Anaesthesia
position in division: https://connects.catalyst.harvard.edu/Profiles/profile/1229413
sort order: 1
type: Position
HR job title: Associate Professor of Anaesthesia
position in organization: Boston Children's Hospital

Elkan Blout Professor of Environmental Genetics
is primary position: true
position in department: Environmental Health
position in division: https://connects.catalyst.harvard.edu/Profiles/profile/1229413
sort order: 1
type: Position
HR job title: Elkan Blout Professor of Environmental Genetics
position in organization: Harvard T.H. Chan School of Public Health

Research Associate in Pediatrics
is primary position: true
position in department: Pediatrics
position in division: Pulmonary
sort order: 1
type: Position
HR job title: Research Associate in Pediatrics
position in organization: Boston Children's Hospital

Associate Professor of Pediatrics
is primary position: true
position in department: Pediatrics
position in division: Pulmonary
sort order: 1
type: Position
HR job title: Associate Professor of Pediatrics
position in organization: Boston Children's Hospital

Assistant Professor of Pediatrics
is primary position: true
position in department: Pediatrics
position in division: Pulmonary
sort order: 1
type: Position
HR job title: Assistant Professor of Pediatrics
position in organization: Boston Children's Hospital

Assistant Professor of Pediatrics
is primary position: true
position in department: Pediatrics
position in division: Pulmonary
sort order: 1
type: Position
HR job title: Assistant Professor of Pediatrics
position in organization: Boston Children's Hospital

James L. Gamble Professor of Pediatrics
is primary position: true
position in department: Pediatrics
position in division: Immunology
sort order: 1
type: Position
HR job title: James L. Gamble Professor of Pediatrics
position in organization: Boston Children's Hospital

Corresponding Member of the Faculty of Pediatrics
is primary position: true
position in department: Pediatrics
position in division: Pulmonary
sort order: 1
type: Position
HR job title: Corresponding Member of the Faculty of Pediatrics
position in organization: Boston Children's Hospital

Authorship 184449
type: Authorship
author rank in publication: 1
linked author: Martin, Thomas
linked information resource: Mast cells contribute to the changes in heart rate, but not hypotension or death, associated with active anaphylaxis in mice.

Authorship 178309
type: Authorship
author rank in publication: 7
linked author: Martin, Thomas
linked information resource: Effect of CD14 blockade in rabbits with Escherichia coli pneumonia and sepsis.

Authorship 174693
type: Authorship
author rank in publication: 6
linked author: Martin, Thomas
linked information resource: Allergen-induced bronchial hyperreactivity and eosinophilic inflammation occur in the absence of IgE in a mouse model of asthma.

Authorship 352890
type: Authorship
author rank in publication: 6
linked author: Martin, Thomas
linked information resource: Sweat testing infants detected by cystic fibrosis newborn screening.

Authorship 361255
type: Authorship
author rank in publication: 3
linked author: Martin, Thomas
linked information resource: Clinically useful spirometry in preschool-aged children: evaluation of the 2007 American Thoracic Society Guidelines.

Authorship 301778
type: Authorship
author rank in publication: 3
linked author: Martin, Thomas
linked information resource: Genetic variability in pulmonary physiological, cellular, and antibody responses to antigen in mice.

Authorship 571533
type: Authorship
author rank in publication: 6
linked author: Martin, Thomas
linked information resource: Mast cell activation is not required for induction of airway hyperresponsiveness by ozone in mice.

Authorship 54824
type: Authorship
author rank in publication: 7
linked author: Martin, Thomas
linked information resource: The murine CCR3 receptor regulates both the role of eosinophils and mast cells in allergen-induced airway inflammation and hyperresponsiveness.

Authorship 403688
type: Authorship
author rank in publication: 6
linked author: Martin, Thomas
linked information resource: Suppression of herpes simplex virus type 1 (HSV-1)-induced pneumonia in mice by inhibition of inducible nitric oxide synthase (iNOS, NOS2).

Authorship 275422
type: Authorship
author rank in publication: 3
linked author: Martin, Thomas
linked information resource: Persistence of pulmonary pathology and abnormal lung function in IL-3/GM-CSF/IL-5 beta c receptor-deficient mice despite correction of alveolar proteinosis after BMT.

Authorship 539252
type: Authorship
author rank in publication: 1
linked author: Martin, Thomas
linked information resource: Mast cell activation enhances airway responsiveness to methacholine in the mouse.

Authorship 518003
type: Authorship
author rank in publication: 1
linked author: Martin, Thomas
linked information resource: Role of mast cells in anaphylaxis. Evidence for the importance of mast cells in the cardiopulmonary alterations and death induced by anti-IgE in mice.

Authorship 52752
type: Authorship
author rank in publication: 2
linked author: Martin, Thomas
linked information resource: SLP-76 deficiency impairs signaling via the high-affinity IgE receptor in mast cells.

Assistant Professor
sort order: 2
type: Faculty Rank

Associate Professor
sort order: 1
type: Faculty Rank

Full Professor
sort order: 0
type: Faculty Rank

Other Faculty
sort order: 5
type: Faculty Rank

NW Research Center for Excellence in Biodefense and Emerging Infectious Diseases
end date: 2014-02-28
principal investigator name: MILLER, SAMUEL I.
start date: 2003-09-04
type: Grant
sponsor award id: U54AI057141

ALVEOLAR MACROPHAGE DERIVED CHEMOATTRACTANTS
end date: 2000-09-30
principal investigator name: MARTIN, THOMAS R
start date: 1990-07-01
type: Grant
sponsor award id: R01AI029103

Molecular Mechanisms of Lung Inflammation
end date: 2002-07-31
principal investigator name: MARTIN, THOMAS R
start date: 2002-04-01
type: Grant
sponsor award id: R01HL070297

SCCOR in Translational Research in Acute Lung Injury
end date: 2009-06-30
principal investigator name: MARTIN, THOMAS R
start date: 2003-09-30
type: Grant
sponsor award id: P50HL073996

Acute Lung Injury: Link Between Apoptosis and Fibrosis
end date: 2013-06-30
principal investigator name: MATUTE-BELLO, GUSTAVO
start date: 2007-09-15
type: Grant
sponsor award id: R01HL081764

SCOR IN ACUTE LUNG INJURY
end date: 2004-11-30
principal investigator name: HUDSON, LEONARD D
start date: 1983-09-30
type: Grant
sponsor award id: P50HL030542

INFLAMMATION AND LUNG EPITHELIAL APOPTOSIS
end date: 2005-08-31
principal investigator name: MARTIN, THOMAS R
start date: 1990-07-01
type: Grant
sponsor award id: R01HL065892

LUNG CELL MEDIATED IMMUNITY IN PROTEIN DEFICIENCY
end date: 1988-05-30
principal investigator name: MARTIN, THOMAS R
start date: 1984-12-01
type: Grant
sponsor award id: R01HL033247

IGE/MAST CELL-DEPENDENT EFFECTS ON PULMONARY FUNCTION
end date: 1995-06-30
principal investigator name: MARTIN, THOMAS R
start date: 1990-07-01
type: Grant
sponsor award id: K11HL002240

BIOCHEMICAL MECHANISMS OF CELLULAR INJURY IN TRAUMA
end date: 2008-07-31
principal investigator name: ULEVITCH, RICHARD J
start date: 1986-12-01
type: Grant
sponsor award id: P01GM037696

Principal Investigator
type: Researcher Role
researcher role of: Martin, Thomas
contributes to: SCCOR in Translational Research in Acute Lung Injury

Principal Investigator
type: Researcher Role
researcher role of: Martin, Thomas
contributes to: Molecular Mechanisms of Lung Inflammation

Co-Principal Investigator
type: Researcher Role
researcher role of: Martin, Thomas
contributes to: NW Research Center for Excellence in Biodefense and Emerging Infectious Diseases

Principal Investigator
type: Researcher Role
researcher role of: Martin, Thomas
contributes to: ALVEOLAR MACROPHAGE DERIVED CHEMOATTRACTANTS

Co-Principal Investigator
type: Researcher Role
researcher role of: Martin, Thomas
contributes to: Acute Lung Injury: Link Between Apoptosis and Fibrosis

Principal Investigator
type: Researcher Role
researcher role of: Martin, Thomas
contributes to: LUNG CELL MEDIATED IMMUNITY IN PROTEIN DEFICIENCY

Principal Investigator
type: Researcher Role
researcher role of: Martin, Thomas
contributes to: IGE/MAST CELL-DEPENDENT EFFECTS ON PULMONARY FUNCTION

Principal Investigator
type: Researcher Role
researcher role of: Martin, Thomas
contributes to: INFLAMMATION AND LUNG EPITHELIAL APOPTOSIS

Co-Principal Investigator
type: Researcher Role
researcher role of: Martin, Thomas
contributes to: SCOR IN ACUTE LUNG INJURY

Co-Principal Investigator
type: Researcher Role
researcher role of: Martin, Thomas
contributes to: BIOCHEMICAL MECHANISMS OF CELLULAR INJURY IN TRAUMA

Authorship 577046
type: Authorship
author rank in publication: 4
linked author: Martin, Thomas
linked information resource: Epicutaneous sensitization with protein antigen induces localized allergic dermatitis and hyperresponsiveness to methacholine after single exposure to aerosolized antigen in mice.

Authorship 195469
type: Authorship
author rank in publication: 9
linked author: Martin, Thomas
linked information resource: Clinical issues and research in respiratory failure from severe acute respiratory syndrome.

Authorship 573493
type: Authorship
author rank in publication: 1
linked author: Martin, Thomas
linked information resource: Serotonin-induced pulmonary responses are mediated by the 5-HT2 receptor in the mouse.

https://connects.catalyst.harvard.edu/Profiles/profile/748261
PubMed Identifier: 9062348
author list: Miyajima I, Dombrowicz D, Martin TR, Ravetch JV, Kinet JP, Galli SJ
published in: The Journal of clinical investigation
information resource reference: Systemic anaphylaxis in the mouse can be mediated largely through IgG1 and Fc gammaRIII. Assessment of the cardiopulmonary changes, mast cell degranulation, and death associated with active or IgE- or IgG1-dependent passive anaphylaxis. J Clin Invest. 1997 Mar 01; 99(5):901-14.
journal title abbreviation: J Clin Invest
publication date: 1997-03-01T00:00:00
year: 1997
type: Academic Article
type: Article
type: Document
type: Information Resource
label: Systemic anaphylaxis in the mouse can be mediated largely through IgG1 and Fc gammaRIII. Assessment of the cardiopulmonary changes, mast cell degranulation, and death associated with active or IgE- or IgG1-dependent passive anaphylaxis.

T-lymphocytes regulate genetically determined airway hyperresponsiveness in mice.
PubMed Identifier: 9095183
author list: De Sanctis GT, Itoh A, Green FH, Qin S, Kimura T, Grobholz JK, Martin TR, Maki T, Drazen JM
published in: Nature medicine
information resource reference: T-lymphocytes regulate genetically determined airway hyperresponsiveness in mice. Nat Med. 1997 Apr; 3(4):460-2.
journal title abbreviation: Nat Med
publication date: 1997-04-01T00:00:00
year: 1997
type: Academic Article
type: Article
type: Document
type: Information Resource

Suppression of herpes simplex virus type 1 (HSV-1)-induced pneumonia in mice by inhibition of inducible nitric oxide synthase (iNOS, NOS2).
PubMed Identifier: 9151890
author list: Adler H, Beland JL, Del-Pan NC, Kobzik L, Brewer JP, Martin TR, Rimm IJ
published in: The Journal of experimental medicine
information resource reference: Suppression of herpes simplex virus type 1 (HSV-1)-induced pneumonia in mice by inhibition of inducible nitric oxide synthase (iNOS, NOS2). J Exp Med. 1997 May 05; 185(9):1533-40.
journal title abbreviation: J Exp Med
publication date: 1997-05-05T00:00:00
year: 1997
type: Academic Article
type: Article
type: Document
type: Information Resource

The role of leukocyte emigration and IL-8 on the development of lipopolysaccharide-induced lung injury in rabbits.
PubMed Identifier: 9820552
author list: Yamamoto T, Kajikawa O, Martin TR, Sharar SR, Harlan JM, Winn RK
published in: Journal of immunology (Baltimore, Md. : 1950)
information resource reference: The role of leukocyte emigration and IL-8 on the development of lipopolysaccharide-induced lung injury in rabbits. J Immunol. 1998 Nov 15; 161(10):5704-9.
journal title abbreviation: J Immunol
publication date: 1998-11-15T00:00:00
year: 1998
type: Academic Article
type: Article
type: Document
type: Information Resource

Pulmonary responses to bronchoconstrictor agonists in the mouse.
PubMed Identifier: 2457008
author list: Martin TR, Gerard NP, Galli SJ, Drazen JM
published in: Journal of applied physiology (Bethesda, Md. : 1985)
information resource reference: Pulmonary responses to bronchoconstrictor agonists in the mouse. J Appl Physiol (1985). 1988 Jun; 64(6):2318-23.
journal title abbreviation: J Appl Physiol (1985)
publication date: 1988-06-01T00:00:00
year: 1988
type: Academic Article
type: Article
type: Document
type: Information Resource

CD40L, but not CD40, is required for allergen-induced bronchial hyperresponsiveness in mice.
PubMed Identifier: 11062143
author list: Mehlhop PD, van de Rijn M, Brewer JP, Kisselgof AB, Geha RS, Oettgen HC, Martin TR
published in: American journal of respiratory cell and molecular biology
information resource reference: CD40L, but not CD40, is required for allergen-induced bronchial hyperresponsiveness in mice. Am J Respir Cell Mol Biol. 2000 Nov; 23(5):646-51.
journal title abbreviation: Am J Respir Cell Mol Biol
publication date: 2000-11-01T00:00:00
year: 2000
type: Academic Article
type: Article
type: Document
type: Information Resource

300 Longwood Ave
type: Address
address line 1: Childrens Hospital
address line 3: 300 Longwood Ave
city: Boston
postal code: 02115
state or province: MA

An experimental model of idiopathic pneumonia syndrome after bone marrow transplantation: I. The roles of minor H antigens and endotoxin.
PubMed Identifier: 8963063
author list: Cooke KR, Kobzik L, Martin TR, Brewer J, Delmonte J, Crawford JM, Ferrara JL
published in: Blood
information resource reference: An experimental model of idiopathic pneumonia syndrome after bone marrow transplantation: I. The roles of minor H antigens and endotoxin. Blood. 1996 Oct 15; 88(8):3230-9.
journal title abbreviation: Blood
publication date: 1996-10-15T00:00:00
year: 1996
type: Academic Article
type: Article
type: Document
type: Information Resource

Allergen-induced bronchial hyperreactivity and eosinophilic inflammation occur in the absence of IgE in a mouse model of asthma.
PubMed Identifier: 9037055
author list: Mehlhop PD, van de Rijn M, Goldberg AB, Brewer JP, Kurup VP, Martin TR, Oettgen HC
published in: Proceedings of the National Academy of Sciences of the United States of America
information resource reference: Allergen-induced bronchial hyperreactivity and eosinophilic inflammation occur in the absence of IgE in a mouse model of asthma. Proc Natl Acad Sci U S A. 1997 Feb 18; 94(4):1344-9.
journal title abbreviation: Proc Natl Acad Sci U S A
publication date: 1997-02-18T00:00:00
year: 1997
type: Academic Article
type: Article
type: Document
type: Information Resource

Effect of CD14 blockade in rabbits with Escherichia coli pneumonia and sepsis.
PubMed Identifier: 10799910
author list: Frevert CW, Matute-Bello G, Skerrett SJ, Goodman RB, Kajikawa O, Sittipunt C, Martin TR
published in: Journal of immunology (Baltimore, Md. : 1950)
information resource reference: Effect of CD14 blockade in rabbits with Escherichia coli pneumonia and sepsis. J Immunol. 2000 May 15; 164(10):5439-45.
journal title abbreviation: J Immunol
publication date: 2000-05-15T00:00:00
year: 2000
type: Academic Article
type: Article
type: Document
type: Information Resource

Hyporesponsiveness of donor cells to lipopolysaccharide stimulation reduces the severity of experimental idiopathic pneumonia syndrome: potential role for a gut-lung axis of inflammation.
PubMed Identifier: 11086106
author list: Cooke KR, Hill GR, Gerbitz A, Kobzik L, Martin TR, Crawford JM, Brewer JP, Ferrara JL
published in: Journal of immunology (Baltimore, Md. : 1950)
information resource reference: Hyporesponsiveness of donor cells to lipopolysaccharide stimulation reduces the severity of experimental idiopathic pneumonia syndrome: potential role for a gut-lung axis of inflammation. J Immunol. 2000 Dec 01; 165(11):6612-9.
journal title abbreviation: J Immunol
publication date: 2000-12-01T00:00:00
year: 2000
type: Academic Article
type: Article
type: Document
type: Information Resource

Targeting pan-resistant bacteria with antibodies to a broadly conserved surface polysaccharide expressed during infection.
PubMed Identifier: 22448004
author list: Skurnik D, Davis MR, Benedetti D, Moravec KL, Cywes-Bentley C, Roux D, Traficante DC, Walsh RL, Maira-Litràn T, Cassidy SK, Hermos CR, Martin TR, Thakkallapalli EL, Vargas SO, McAdam AJ, Lieberman TD, Kishony R, Lipuma JJ, Pier GB, Goldberg JB, Priebe GP
published in: The Journal of infectious diseases
information resource reference: Targeting pan-resistant bacteria with antibodies to a broadly conserved surface polysaccharide expressed during infection. J Infect Dis. 2012 Jun; 205(11):1709-18.
journal title abbreviation: J Infect Dis
publication date: 2012-03-23T00:00:00
year: 2012
type: Academic Article
type: Article
type: Document
type: Information Resource

Cytokine balance in the lungs of patients with acute respiratory distress syndrome.
PubMed Identifier: 11734443
author list: Park WY, Goodman RB, Steinberg KP, Ruzinski JT, Radella F, Park DR, Pugin J, Skerrett SJ, Hudson LD, Martin TR
published in: American journal of respiratory and critical care medicine
information resource reference: Cytokine balance in the lungs of patients with acute respiratory distress syndrome. Am J Respir Crit Care Med. 2001 Nov 15; 164(10 Pt 1):1896-903.
journal title abbreviation: Am J Respir Crit Care Med
publication date: 2001-11-15T00:00:00
year: 2001
type: Academic Article
type: Article
type: Document
type: Information Resource

Clinical issues and research in respiratory failure from severe acute respiratory syndrome.
PubMed Identifier: 15591472
author list: Levy MM, Baylor MS, Bernard GR, Fowler R, Franks TJ, Hayden FG, Helfand R, Lapinsky SE, Martin TR, Niederman MS, Rubenfeld GD, Slutsky AS, Stewart TE, Styrt BA, Thompson BT, Harabin AL
published in: American journal of respiratory and critical care medicine
information resource reference: Clinical issues and research in respiratory failure from severe acute respiratory syndrome. Am J Respir Crit Care Med. 2005 Mar 01; 171(5):518-26.
journal title abbreviation: Am J Respir Crit Care Med
publication date: 2004-12-10T00:00:00
year: 2004
type: Academic Article
type: Article
type: Document
type: Information Resource

Serotonin-induced pulmonary responses are mediated by the 5-HT2 receptor in the mouse.
PubMed Identifier: 8301545
author list: Martin TR, Cohen ML, Drazen JM
published in: The Journal of pharmacology and experimental therapeutics
information resource reference: Serotonin-induced pulmonary responses are mediated by the 5-HT2 receptor in the mouse. J Pharmacol Exp Ther. 1994 Jan; 268(1):104-9.
journal title abbreviation: J Pharmacol Exp Ther
publication date: 1994-01-01T00:00:00
year: 1994
type: Academic Article
type: Article
type: Document
type: Information Resource

Depletion of phagocytes in the reticuloendothelial system causes increased inflammation and mortality in rabbits with Pseudomonas aeruginosa pneumonia.
PubMed Identifier: 19028978
author list: Kurahashi K, Sawa T, Ota M, Kajikawa O, Hong K, Martin TR, Wiener-Kronish JP
published in: American journal of physiology. Lung cellular and molecular physiology
information resource reference: Depletion of phagocytes in the reticuloendothelial system causes increased inflammation and mortality in rabbits with Pseudomonas aeruginosa pneumonia. Am J Physiol Lung Cell Mol Physiol. 2009 Feb; 296(2):L198-209.
journal title abbreviation: Am J Physiol Lung Cell Mol Physiol
publication date: 2008-11-21T00:00:00
year: 2008
type: Academic Article
type: Article
type: Document
type: Information Resource

Mast cells contribute to the changes in heart rate, but not hypotension or death, associated with active anaphylaxis in mice.
PubMed Identifier: 7686942
author list: Martin TR, Ando A, Takeishi T, Katona IM, Drazen JM, Galli SJ
published in: Journal of immunology (Baltimore, Md. : 1950)
information resource reference: Mast cells contribute to the changes in heart rate, but not hypotension or death, associated with active anaphylaxis in mice. J Immunol. 1993 Jul 01; 151(1):367-76.
journal title abbreviation: J Immunol
publication date: 1993-07-01T00:00:00
year: 1993
type: Academic Article
type: Article
type: Document
type: Information Resource

Host reactive donor T cells are associated with lung injury after experimental allogeneic bone marrow transplantation.
PubMed Identifier: 9746799
author list: Cooke KR, Krenger W, Hill G, Martin TR, Kobzik L, Brewer J, Simmons R, Crawford JM, van den Brink MR, Ferrara JL
published in: Blood
information resource reference: Host reactive donor T cells are associated with lung injury after experimental allogeneic bone marrow transplantation. Blood. 1998 Oct 01; 92(7):2571-80.
journal title abbreviation: Blood
publication date: 1998-10-01T00:00:00
year: 1998
type: Academic Article
type: Article
type: Document
type: Information Resource

Mast cell activation is not required for induction of airway hyperresponsiveness by ozone in mice.
PubMed Identifier: 9887132
author list: Noviski N, Brewer JP, Skornik WA, Galli SJ, Drazen JM, Martin TR
published in: Journal of applied physiology (Bethesda, Md. : 1985)
information resource reference: Mast cell activation is not required for induction of airway hyperresponsiveness by ozone in mice. J Appl Physiol (1985). 1999 Jan; 86(1):202-10.
journal title abbreviation: J Appl Physiol (1985)
publication date: 1999-01-01T00:00:00
year: 1999
type: Academic Article
type: Article
type: Document
type: Information Resource

Pulmonary and systemic inflammatory responses in rabbits with gram-negative pneumonia.
PubMed Identifier: 9196112
author list: Fox-Dewhurst R, Alberts MK, Kajikawa O, Caldwell E, Johnson MC, Skerrett SJ, Goodman RB, Ruzinski JT, Wong VA, Chi EY, Martin TR
published in: American journal of respiratory and critical care medicine
information resource reference: Pulmonary and systemic inflammatory responses in rabbits with gram-negative pneumonia. Am J Respir Crit Care Med. 1997 Jun; 155(6):2030-40.
journal title abbreviation: Am J Respir Crit Care Med
publication date: 1997-06-01T00:00:00
year: 1997
type: Academic Article
type: Article
type: Document
type: Information Resource

Persistence of pulmonary pathology and abnormal lung function in IL-3/GM-CSF/IL-5 beta c receptor-deficient mice despite correction of alveolar proteinosis after BMT.
PubMed Identifier: 9383229
author list: Cooke KR, Nishinakamura R, Martin TR, Kobzik L, Brewer J, Whitsett JA, Bungard D, Murray R, Ferrara JL
published in: Bone marrow transplantation
information resource reference: Persistence of pulmonary pathology and abnormal lung function in IL-3/GM-CSF/IL-5 beta c receptor-deficient mice despite correction of alveolar proteinosis after BMT. Bone Marrow Transplant. 1997 Oct; 20(8):657-62.
journal title abbreviation: Bone Marrow Transplant
publication date: 1997-10-01T00:00:00
year: 1997
type: Academic Article
type: Article
type: Document
type: Information Resource

Epicutaneous sensitization with protein antigen induces localized allergic dermatitis and hyperresponsiveness to methacholine after single exposure to aerosolized antigen in mice.
PubMed Identifier: 9541491
author list: Spergel JM, Mizoguchi E, Brewer JP, Martin TR, Bhan AK, Geha RS
published in: The Journal of clinical investigation
information resource reference: Epicutaneous sensitization with protein antigen induces localized allergic dermatitis and hyperresponsiveness to methacholine after single exposure to aerosolized antigen in mice. J Clin Invest. 1998 Apr 15; 101(8):1614-22.
journal title abbreviation: J Clin Invest
publication date: 1998-04-15T00:00:00
year: 1998
type: Academic Article
type: Article
type: Document
type: Information Resource