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Mallinckrodt Professor of Pharmacology in the Department of Anaesthesia
McNeil Family Professor of Health Care Policy
Dr. Henry Isaiah Dorr Professor of Research and Teaching in Anaesthetics and Anaesthesia
Edward Mallinckrodt Jr. Professor of Anaesthesia in the Field of Pharmacology and Innovation
Warren M. Zapol Professor of Anaesthesia
Melonakos ED, Moody OA, Nikolaeva K, Kato R, Nehs CJ, Solt K
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Activation of GABAergic Neurons in the Rostromedial Tegmental Nucleus and Other Brainstem Regions Promotes Sedation and Facilitates Sevoflurane Anesthesia in Mice.
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The Neural Circuits Underlying General Anesthesia and Sleep. Anesth Analg. 2021 05 01; 132(5):1254-1264.
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D-Amphetamine Rapidly Reverses Dexmedetomidine-Induced Unconsciousness in Rats. Front Pharmacol. 2021; 12:668285.
D-Amphetamine Rapidly Reverses Dexmedetomidine-Induced Unconsciousness in Rats.
Melonakos ED, Siegmann MJ, Rey C, O'Brien C, Nikolaeva KK, Solt K, Nehs CJ
Excitation of Putative Glutamatergic Neurons in the Rat Parabrachial Nucleus Region Reduces Delta Power during Dexmedetomidine but not Ketamine Anesthesia. Anesthesiology. 2021 10 01; 135(4):633-648.
Excitation of Putative Glutamatergic Neurons in the Rat Parabrachial Nucleus Region Reduces Delta Power during Dexmedetomidine but not Ketamine Anesthesia.
Kang J, Lee M, Park M, Lee J, Lee S, Park J, Koyanagi A, Smith L, Nehs CJ, Yon DK, Kim T
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Sleep, mood disorders, and the ketogenic diet: potential therapeutic targets for bipolar disorder and schizophrenia.
Kang J, Lee H, Yu S, Lee M, Kim HJ, Kwon R, Kim S, Fond G, Boyer L, Rahmati M, Koyanagi A, Smith L, Nehs CJ, Kim MS, Sánchez GFL, Dragioti E, Kim T, Yon DK
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Effects and safety of transcranial direct current stimulation on multiple health outcomes: an umbrella review of randomized clinical trials.
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Comorbid physical health outcomes in patients with bipolar disorder: An umbrella review of systematic reviews and meta-analyses.
Kim S, Lee H, Woo S, Lee H, Park J, Kim T, Fond G, Boyer L, Rahmati M, Smith L, López Sánchez GF, Dragioti E, Nehs CJ, Lee J, Kim HJ, Kang J, Yon DK
Global, regional, and national trends in drug use disorder mortality rates across 73 countries from 1990 to 2021, with projections up to 2040: a global time-series analysis and modelling study. EClinicalMedicine. 2025 Jan; 79:102985.
Global, regional, and national trends in drug use disorder mortality rates across 73 countries from 1990 to 2021, with projections up to 2040: a global time-series analysis and modelling study.
Siegmann MJ, Parry S, Lark ARS, Mir FA, Choi J, Carpenter AH, Crowley EA, White CG, Kang J, Purdon PL, Nehs CJ
A ketogenic diet decreases sevoflurane-induced burst suppression in rats. Brain Res Bull. 2025 Apr; 223:111274.
A ketogenic diet decreases sevoflurane-induced burst suppression in rats.
Son Y, Hong S, Yim Y, Kim S, Lee H, Lee K, Kim HJ, Jo H, Park J, Oh J, Lee S, Lee H, Nehs CJ, Smith L, Yon DK, Kang J
Global prevalence of cannabis and amphetamine/methamphetamine use among adolescents in 47 countries: a population-based study from WHO database. World J Pediatr. 2025 03; 21(3):291-305.
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Trifluoroacetic Acid Induced a Cyclophilin D-Dependent Cognitive Impairment in Mice.
Jang W, Cho H, Kim S, Boyer L, Fond G, Kang J, Nehs CJ, Pizzol D, Lee S, Oh J, Kim HJ, Son Y, Lee H, Yon DK
Global burden of anxiety, depression, and self-harm (1990-2021) and the impact of the COVID-19 pandemic. J Affect Disord. 2026 Jan 01; 392:120201.
Global burden of anxiety, depression, and self-harm (1990-2021) and the impact of the COVID-19 pandemic.
Kang J, Park J, Kim HJ, Lee H, Fond G, Boyer L, Rahmati M, Nehs CJ, Smith L, Yon DK
Association of Unmet Healthcare Needs With Depressive Symptoms and COVID-19 Pandemic-Related Factors Among Adults, 2009-2022: A Nationwide Study in Korea. J Korean Med Sci. 2025 Dec 08; 40(47):e307.
Association of Unmet Healthcare Needs With Depressive Symptoms and COVID-19 Pandemic-Related Factors Among Adults, 2009-2022: A Nationwide Study in Korea.
Lee H, Kim H, Kim HJ, Son Y, Park J, Kim K, Nehs CJ, Pizzol D, Yon DK, Kang J
International archives of allergy and immunology
Trends in Suicidal Ideation and Sadness among Adolescents by Atopic Dermatitis Status, 2007-2024: A Nationwide Representative Study in South Korea. Int Arch Allergy Immunol. 2025 Nov 29; 1-26.
Trends in Suicidal Ideation and Sadness among Adolescents by Atopic Dermatitis Status, 2007-2024: A Nationwide Representative Study in South Korea.
Kim MS, Kim K, Lee K, Nehs CJ, Pizzol D, Kang J, Yon DK
Journal of science and medicine in sport
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Trends in physical activity among South Korean adults before, during, and after the COVID-19 pandemic, 2009-2024: A nationwide representative study.
Kim TH, Lee K, Hwang J, Lee S, Jo H, Cho H, Lee H, Baek HJ, Kang J, Nehs CJ, Fond G, Boyer L, Chung EK, Yon DK
Adverse event reports of seizure for insomnia medication from 1967 to 2023. Sci Rep. 2025 Jul 26; 15(1):27308.
Adverse event reports of seizure for insomnia medication from 1967 to 2023.
Kim S, Son Y, Oh J, Kim S, Jang W, Lee S, Smith L, Pizzol D, Lee J, Lee H, Nehs CJ, Nehs MA, Jung J, Kang J, Yon DK
Global burden of brain and central nervous system cancer in 185 countries, and projections up to 2050: a population-based systematic analysis of GLOBOCAN 2022. J Neurooncol. 2025 Nov; 175(2):673-685.
Global burden of brain and central nervous system cancer in 185 countries, and projections up to 2050: a population-based systematic analysis of GLOBOCAN 2022.
Kang J, Kim HJ, Lark ARS, Mir FA, Park J, Son Y, Fond G, Boyer L, Rahmati M, Smith L, Yon DK, Nehs CJ
Association of Everyday Discrimination With Drug Use During the COVID-19 Pandemic in the All of Us Research Program. Psychiatry Investig. 2026 Jan; 23(1):118-129.
Association of Everyday Discrimination With Drug Use During the COVID-19 Pandemic in the All of Us Research Program.
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Anesthesiology and perioperative science
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Neurophysiological differences between dexmedetomidine sedation and natural sleep across the rodent lifespan: implications for aging and perioperative brain health.
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Association of Sleep Duration With Asthma and Allergic Rhinitis in South Korea: A Nationwide Representative Study.
Kim HJ, Yim Y, Nehs CJ, Park J, Kim S, Papadopoulos NG, Kang J, Yon DK
Maternal Opioid Use and Subsequent Risk of Allergic Diseases in Children: Emulation of Target Trials Using the Korean Nationwide Birth Cohort. Allergy. 2026 Apr; 81(4):1293-1296.
Maternal Opioid Use and Subsequent Risk of Allergic Diseases in Children: Emulation of Target Trials Using the Korean Nationwide Birth Cohort.
Kang J, Kim HJ, Jo Y, Smith KJ, Lark ARS, Mir FA, Park J, Lee H, Kim Y, Rahmati M, Smith L, Rhee SY, Son Y, Yon DK, Nehs CJ
Obesity reviews : an official journal of the International Association for the Study of Obesity
Gestational Diabetes Mellitus and Adverse Maternal and Neonatal Health Outcomes: an Umbrella review of Meta-Analyses. Obes Rev. 2026 Feb 23; e70102.
Gestational Diabetes Mellitus and Adverse Maternal and Neonatal Health Outcomes: an Umbrella review of Meta-Analyses.
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Reply to Grace: Role of cholinergic neurons in rapid eye movement (REM) sleep control. Proc Natl Acad Sci U S A. 2015 Jul 21; 112(29):E3756.
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Locus Coeruleus Neural Fatigue: A Potential Mechanism for Cognitive Impairment during Sleep Deprivation. Sleep. 2016 Jan 01; 39(1):11-2.
Locus Coeruleus Neural Fatigue: A Potential Mechanism for Cognitive Impairment during Sleep Deprivation.
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Physostigmine and Methylphenidate Induce Distinct Arousal States During Isoflurane General Anesthesia in Rats.
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Optogenetic activation of dopamine neurons in the ventral tegmental area induces reanimation from general anesthesia.
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Biochemical and biophysical research communications
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American journal of physiology. Cell physiology
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Expression of VACM-1/cul5 mutant in endothelial cells induces MAPK phosphorylation and maspin degradation and converts cells to the angiogenic phenotype.
Zhang H, Zhao H, Zeng C, Van Dort C, Faingold CL, Taylor NE, Solt K, Feng HJ
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Optogenetic activation of 5-HT neurons in the dorsal raphe suppresses seizure-induced respiratory arrest and produces anticonvulsant effect in the DBA/1 mouse SUDEP model.
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Active emergence from propofol general anesthesia is induced by methylphenidate.