Brugnara, Carlo
eCommons Login: CB18
first name: Carlo
last name: Brugnara
coauthor of: Alper, Seth
coauthor of: Rivera, Alicia
coauthor of: Rifai, Nader
coauthor of: Platt, Orah
coauthor of: Vandorpe, David
full name: Carlo Brugnara, M.D.
has faculty rank: Full Professor
has network: selected publications
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latitude: 42.33743600000000
longitude: -71.10544700000000
Person ID: 77413
person in primary position: Professor of Pathology
physical neighbor: Fleming, Mark
physical neighbor: Kozakewich, Harry
physical neighbor: Lidov, Hart
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physical neighbor: Schmidt, Birgitta
similar to: Alper, Seth
similar to: Cowman, Alan
similar to: Stowell, Sean
similar to: Duraisingh, Manoj
similar to: Heeney, Matthew
type: Agent
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selected publications: Authorship 1816104
selected publications: Authorship 1749905
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selected publications: Authorship 1112605

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Reticulocyte hemoglobin content to diagnose iron deficiency in children.
PubMed Identifier: 10376576
author list: Brugnara C, Zurakowski D, DiCanzio J, Boyd T, Platt O
published in: JAMA
information resource reference: Reticulocyte hemoglobin content to diagnose iron deficiency in children. JAMA. 1999 Jun 16; 281(23):2225-30.
journal title abbreviation: JAMA
publication date: 1999-06-16T00:00:00
year: 1999
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1048941
type: Authorship
author rank in publication: 4
linked author: Brugnara, Carlo
linked information resource: Positive Iron Balance in Chronic Kidney Disease: How Much is Too Much and How to Tell?

Positive Iron Balance in Chronic Kidney Disease: How Much is Too Much and How to Tell?
PubMed Identifier: 29439253
author list: Wish JB, Aronoff GR, Bacon BR, Brugnara C, Eckardt KU, Ganz T, Macdougall IC, Núñez J, Perahia AJ, Wood JC
published in: American journal of nephrology
information resource reference: Positive Iron Balance in Chronic Kidney Disease: How Much is Too Much and How to Tell? Am J Nephrol. 2018; 47(2):72-83.
journal title abbreviation: Am J Nephrol
publication date: 2018-02-13T00:00:00
year: 2018
type: Academic Article
type: Article
type: Document
type: Information Resource

ICA-17043, a novel Gardos channel blocker, prevents sickled red blood cell dehydration in vitro and in vivo in SAD mice.
PubMed Identifier: 12433690
author list: Stocker JW, De Franceschi L, McNaughton-Smith GA, Corrocher R, Beuzard Y, Brugnara C
published in: Blood
information resource reference: ICA-17043, a novel Gardos channel blocker, prevents sickled red blood cell dehydration in vitro and in vivo in SAD mice. Blood. 2003 Mar 15; 101(6):2412-8.
journal title abbreviation: Blood
publication date: 2002-11-14T00:00:00
year: 2002
type: Academic Article
type: Article
type: Document
type: Information Resource

Voltage-activated cation permeability in high-potassium but not low-potassium red blood cells.
PubMed Identifier: 1694398
author list: Halperin JA, Brugnara C, Van Ha T, Tosteson DC
published in: The American journal of physiology
information resource reference: Voltage-activated cation permeability in high-potassium but not low-potassium red blood cells. Am J Physiol. 1990 Jun; 258(6 Pt 1):C1169-72.
journal title abbreviation: Am J Physiol
publication date: 1990-06-01T00:00:00
year: 1990
type: Academic Article
type: Article
type: Document
type: Information Resource

Ca(2+)-activated K+ transport in erythrocytes. Comparison of binding and transport inhibition by scorpion toxins.
PubMed Identifier: 7682555
author list: Brugnara C, De Franceschi L, Alper SL
published in: The Journal of biological chemistry
information resource reference: Ca(2+)-activated K+ transport in erythrocytes. Comparison of binding and transport inhibition by scorpion toxins. J Biol Chem. 1993 Apr 25; 268(12):8760-8.
journal title abbreviation: J Biol Chem
publication date: 1993-04-25T00:00:00
year: 1993
type: Academic Article
type: Article
type: Document
type: Information Resource

Abnormal regulation of Mg2+ transport via Na/Mg exchanger in sickle erythrocytes.
PubMed Identifier: 15353477
author list: Rivera A, Ferreira A, Bertoni D, Romero JR, Brugnara C
published in: Blood
information resource reference: Abnormal regulation of Mg2+ transport via Na/Mg exchanger in sickle erythrocytes. Blood. 2005 Jan 01; 105(1):382-6.
journal title abbreviation: Blood
publication date: 2004-09-07T00:00:00
year: 2004
type: Academic Article
type: Article
type: Document
type: Information Resource

Electrolyte composition and equilibrium in hemoglobin CC red blood cells.
PubMed Identifier: 6535334
author list: Brugnara C, Kopin AS, Bunn HF, Tosteson DC
published in: Transactions of the Association of American Physicians
information resource reference: Electrolyte composition and equilibrium in hemoglobin CC red blood cells. Trans Assoc Am Physicians. 1984; 97:104-12.
journal title abbreviation: Trans Assoc Am Physicians
publication date: 1984-01-01T00:00:00
year: 1984
type: Academic Article
type: Article
type: Document
type: Information Resource

Oral administration of clotrimazole and blockade of human erythrocyte Ca(++)-activated K+ channel: the imidazole ring is not required for inhibitory activity.
PubMed Identifier: 7714775
author list: Brugnara C, Armsby CC, Sakamoto M, Rifai N, Alper SL, Platt O
published in: The Journal of pharmacology and experimental therapeutics
information resource reference: Oral administration of clotrimazole and blockade of human erythrocyte Ca(++)-activated K+ channel: the imidazole ring is not required for inhibitory activity. J Pharmacol Exp Ther. 1995 Apr; 273(1):266-72.
journal title abbreviation: J Pharmacol Exp Ther
publication date: 1995-04-01T00:00:00
year: 1995
type: Academic Article
type: Article
type: Document
type: Information Resource

Efficacy of different dosing regimens for recombinant human erythropoietin in a simulated perisurgical setting: the importance of iron availability in optimizing response.
PubMed Identifier: 8109598
author list: Rutherford CJ, Schneider TJ, Dempsey H, Kirn DH, Brugnara C, Goldberg MA
published in: The American journal of medicine
information resource reference: Efficacy of different dosing regimens for recombinant human erythropoietin in a simulated perisurgical setting: the importance of iron availability in optimizing response. Am J Med. 1994 Feb; 96(2):139-45.
journal title abbreviation: Am J Med
publication date: 1994-02-01T00:00:00
year: 1994
type: Academic Article
type: Article
type: Document
type: Information Resource

Degree of agreement in plasma fibrinogen among two functional and one immunonephelometric assays.
PubMed Identifier: 9128264
author list: Magnani B, Fenton T, Lapp C, Brugnara C
published in: American journal of clinical pathology
information resource reference: Degree of agreement in plasma fibrinogen among two functional and one immunonephelometric assays. Am J Clin Pathol. 1997 May; 107(5):527-33.
journal title abbreviation: Am J Clin Pathol
publication date: 1997-05-01T00:00:00
year: 1997
type: Academic Article
type: Article
type: Document
type: Information Resource

Novel AE1 mutations in recessive distal renal tubular acidosis. Loss-of-function is rescued by glycophorin A.
PubMed Identifier: 9854053
author list: Tanphaichitr VS, Sumboonnanonda A, Ideguchi H, Shayakul C, Brugnara C, Takao M, Veerakul G, Alper SL
published in: The Journal of clinical investigation
information resource reference: Novel AE1 mutations in recessive distal renal tubular acidosis. Loss-of-function is rescued by glycophorin A. J Clin Invest. 1998 Dec 15; 102(12):2173-9.
journal title abbreviation: J Clin Invest
publication date: 1998-12-15T00:00:00
year: 1998
type: Academic Article
type: Article
type: Document
type: Information Resource

Targeted disruption of the beta adducin gene (Add2) causes red blood cell spherocytosis in mice.
PubMed Identifier: 10485892
author list: Gilligan DM, Lozovatsky L, Gwynn B, Brugnara C, Mohandas N, Peters LL
published in: Proceedings of the National Academy of Sciences of the United States of America
information resource reference: Targeted disruption of the beta adducin gene (Add2) causes red blood cell spherocytosis in mice. Proc Natl Acad Sci U S A. 1999 Sep 14; 96(19):10717-22.
journal title abbreviation: Proc Natl Acad Sci U S A
publication date: 1999-09-14T00:00:00
year: 1999
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 104965
type: Authorship
author rank in publication: 2
linked author: Brugnara, Carlo
linked information resource: Structure and genetic polymorphism of the mouse KCC1 gene.

Authorship 1056580
type: Authorship
author rank in publication: 1
linked author: Brugnara, Carlo
linked information resource: Sickle cell dehydration: Pathophysiology and therapeutic applications.

Sickle cell dehydration: Pathophysiology and therapeutic applications.
PubMed Identifier: 29614632
author list: Brugnara C
published in: Clinical hemorheology and microcirculation
information resource reference: Sickle cell dehydration: Pathophysiology and therapeutic applications. Clin Hemorheol Microcirc. 2018; 68(2-3):187-204.
journal title abbreviation: Clin Hemorheol Microcirc
publication date: 2018-01-01T00:00:00
year: 2018
type: Academic Article
type: Article
type: Document
type: Information Resource

HPLC measurement, blood distribution, and pharmacokinetics of oral clotrimazole, potentially useful antisickling agent.
PubMed Identifier: 7882513
author list: Rifai N, Sakamoto M, Law T, Platt O, Mikati M, Armsby CC, Brugnara C
published in: Clinical chemistry
information resource reference: HPLC measurement, blood distribution, and pharmacokinetics of oral clotrimazole, potentially useful antisickling agent. Clin Chem. 1995 Mar; 41(3):387-91.
journal title abbreviation: Clin Chem
publication date: 1995-03-01T00:00:00
year: 1995
type: Academic Article
type: Article
type: Document
type: Information Resource

Management training for pathology residents. I. Results of a national survey.
PubMed Identifier: 8178760
author list: Brugnara C, Fenton T, Winkelman JW
published in: American journal of clinical pathology
information resource reference: Management training for pathology residents. I. Results of a national survey. Am J Clin Pathol. 1994 May; 101(5):559-63.
journal title abbreviation: Am J Clin Pathol
publication date: 1994-05-01T00:00:00
year: 1994
type: Academic Article
type: Article
type: Document
type: Information Resource

Combination therapy of erythropoietin, hydroxyurea, and clotrimazole in a beta thalassemic mouse: a model for human therapy.
PubMed Identifier: 8562946
author list: de Franceschi L, Rouyer-Fessard P, Alper SL, Jouault H, Brugnara C, Beuzard Y
published in: Blood
information resource reference: Combination therapy of erythropoietin, hydroxyurea, and clotrimazole in a beta thalassemic mouse: a model for human therapy. Blood. 1996 Feb 01; 87(3):1188-95.
journal title abbreviation: Blood
publication date: 1996-02-01T00:00:00
year: 1996
type: Academic Article
type: Article
type: Document
type: Information Resource

Therapy with oral clotrimazole induces inhibition of the Gardos channel and reduction of erythrocyte dehydration in patients with sickle cell disease.
PubMed Identifier: 8636434
author list: Brugnara C, Gee B, Armsby CC, Kurth S, Sakamoto M, Rifai N, Alper SL, Platt OS
published in: The Journal of clinical investigation
information resource reference: Therapy with oral clotrimazole induces inhibition of the Gardos channel and reduction of erythrocyte dehydration in patients with sickle cell disease. J Clin Invest. 1996 Mar 01; 97(5):1227-34.
journal title abbreviation: J Clin Invest
publication date: 1996-03-01T00:00:00
year: 1996
type: Academic Article
type: Article
type: Document
type: Information Resource

Resistance to osmotic lysis in BXD-31 mouse erythrocytes: association with upregulated K-Cl cotransport.
PubMed Identifier: 8638668
author list: Armsby CC, Stuart-Tilley AK, Alper SL, Brugnara C
published in: The American journal of physiology
information resource reference: Resistance to osmotic lysis in BXD-31 mouse erythrocytes: association with upregulated K-Cl cotransport. Am J Physiol. 1996 Mar; 270(3 Pt 1):C866-77.
journal title abbreviation: Am J Physiol
publication date: 1996-03-01T00:00:00
year: 1996
type: Academic Article
type: Article
type: Document
type: Information Resource

A dominant negative mutant of the KCC1 K-Cl cotransporter: both N- and C-terminal cytoplasmic domains are required for K-Cl cotransport activity.
PubMed Identifier: 11551954
author list: Casula S, Shmukler BE, Wilhelm S, Stuart-Tilley AK, Su W, Chernova MN, Brugnara C, Alper SL
published in: The Journal of biological chemistry
information resource reference: A dominant negative mutant of the KCC1 K-Cl cotransporter: both N- and C-terminal cytoplasmic domains are required for K-Cl cotransport activity. J Biol Chem. 2001 Nov 09; 276(45):41870-8.
journal title abbreviation: J Biol Chem
publication date: 2001-09-10T00:00:00
year: 2001
type: Academic Article
type: Article
type: Document
type: Information Resource

A hematologic "gold standard" for iron-deficient states?
PubMed Identifier: 12089163
author list: Brugnara C
published in: Clinical chemistry
information resource reference: A hematologic "gold standard" for iron-deficient states? Clin Chem. 2002 Jul; 48(7):981-2.
journal title abbreviation: Clin Chem
publication date: 2002-07-01T00:00:00
year: 2002
type: Academic Article
type: Article
type: Document
type: Information Resource

Pediatric laboratory medicine: current challenges and future opportunities.
PubMed Identifier: 12090415
author list: Coffin CM, Hamilton MS, Pysher TJ, Bach P, Ashwood E, Schweiger J, Monahan D, Perry D, Rogers BB, Brugnara C, Rutledge J, Weiss R, Ash O, Hill H, Meikle W, Roberts W, Geaghan S
published in: American journal of clinical pathology
information resource reference: Pediatric laboratory medicine: current challenges and future opportunities. Am J Clin Pathol. 2002 May; 117(5):683-90.
journal title abbreviation: Am J Clin Pathol
publication date: 2002-05-01T00:00:00
year: 2002
type: Academic Article
type: Article
type: Document
type: Information Resource

Full disclosure in industry-sponsored laboratory medicine research studies: statement by the Consortium of Laboratory Medicine Journal Editors.
PubMed Identifier: 21233327
author list: Rifai N, Plebani M, Wu A, Brugnara C, Delvin E, Lamb EJ, Ness PM, Wick MR, Berg JP
published in: Annals of clinical biochemistry
information resource reference: Full disclosure in industry-sponsored laboratory medicine research studies: statement by the Consortium of Laboratory Medicine Journal Editors. Ann Clin Biochem. 2011 Jan; 48(Pt 1):5-6.
journal title abbreviation: Ann Clin Biochem
publication date: 2011-01-13T00:00:00
year: 2011
type: Academic Article
type: Article
type: Document
type: Information Resource

Complement induces a transient increase in membrane permeability in unlysed erythrocytes.
PubMed Identifier: 3403718
author list: Halperin JA, Nicholson-Weller A, Brugnara C, Tosteson DC
published in: The Journal of clinical investigation
information resource reference: Complement induces a transient increase in membrane permeability in unlysed erythrocytes. J Clin Invest. 1988 Aug; 82(2):594-600.
journal title abbreviation: J Clin Invest
publication date: 1988-08-01T00:00:00
year: 1988
type: Academic Article
type: Article
type: Document
type: Information Resource

Inhibition of Ca(2+)-dependent K+ transport and cell dehydration in sickle erythrocytes by clotrimazole and other imidazole derivatives.
PubMed Identifier: 8326017
author list: Brugnara C, de Franceschi L, Alper SL
published in: The Journal of clinical investigation
information resource reference: Inhibition of Ca(2+)-dependent K+ transport and cell dehydration in sickle erythrocytes by clotrimazole and other imidazole derivatives. J Clin Invest. 1993 Jul; 92(1):520-6.
journal title abbreviation: J Clin Invest
publication date: 1993-07-01T00:00:00
year: 1993
type: Academic Article
type: Article
type: Document
type: Information Resource

[Clinical trials of new therapeutic pharmacology for sickle cell disease].
PubMed Identifier: 17446160
author list: Brugnara C, de Franceschi L
published in: Sante (Montrouge, France)
information resource reference: [Clinical trials of new therapeutic pharmacology for sickle cell disease]. Sante. 2006 Oct-Dec; 16(4):263-8.
journal title abbreviation: Sante
publication date: 2006-10-01T00:00:00
year: 2006
type: Academic Article
type: Article
type: Document
type: Information Resource

Quantitative trait loci for peripheral blood cell counts: a study in baboons.
PubMed Identifier: 17557178
author list: Bertin A, Mahaney MC, Cox LA, Rogers J, VandeBerg JL, Brugnara C, Platt OS
published in: Mammalian genome : official journal of the International Mammalian Genome Society
information resource reference: Quantitative trait loci for peripheral blood cell counts: a study in baboons. Mamm Genome. 2007 May; 18(5):361-72.
journal title abbreviation: Mamm Genome
publication date: 2007-06-08T00:00:00
year: 2007
type: Academic Article
type: Article
type: Document
type: Information Resource

Properties of the Na+-K+ pump in human red cells with increased number of pump sites.
PubMed Identifier: 2439543
author list: Halperin JA, Brugnara C, Kopin AS, Ingwall J, Tosteson DC
published in: The Journal of clinical investigation
information resource reference: Properties of the Na+-K+ pump in human red cells with increased number of pump sites. J Clin Invest. 1987 Jul; 80(1):128-37.
journal title abbreviation: J Clin Invest
publication date: 1987-07-01T00:00:00
year: 1987
type: Academic Article
type: Article
type: Document
type: Information Resource

Full disclosure in industry-sponsored laboratory medicine research studies: statement by the Consortium of Laboratory Medicine Journal Editors.
PubMed Identifier: 21173108
author list: Rifai N, Plebani M, Wu A, Brugnara C, Delvin E, Lamb EJ, Ness PM, Wick MR, Berg JP
published in: Clinical chemistry
information resource reference: Full disclosure in industry-sponsored laboratory medicine research studies: statement by the Consortium of Laboratory Medicine Journal Editors. Clin Chem. 2011 Mar; 57(3):359-60.
journal title abbreviation: Clin Chem
publication date: 2010-12-20T00:00:00
year: 2010
type: Academic Article
type: Article
type: Document
type: Information Resource

Treatment of sickle cell anemia with hydroxyurea and erythropoietin.
PubMed Identifier: 1695325
author list: Goldberg MA, Brugnara C, Dover GJ, Schapira L, Charache S, Bunn HF
published in: The New England journal of medicine
information resource reference: Treatment of sickle cell anemia with hydroxyurea and erythropoietin. N Engl J Med. 1990 Aug 09; 323(6):366-72.
journal title abbreviation: N Engl J Med
publication date: 1990-08-09T00:00:00
year: 1990
type: Academic Article
type: Article
type: Document
type: Information Resource

Hemoglobin variants and activity of the (K+Cl-) cotransport system in human erythrocytes.
PubMed Identifier: 1732017
author list: Olivieri O, Vitoux D, Galacteros F, Bachir D, Blouquit Y, Beuzard Y, Brugnara C
published in: Blood
information resource reference: Hemoglobin variants and activity of the (K+Cl-) cotransport system in human erythrocytes. Blood. 1992 Feb 01; 79(3):793-7.
journal title abbreviation: Blood
publication date: 1992-02-01T00:00:00
year: 1992
type: Academic Article
type: Article
type: Document
type: Information Resource

An appeal to medical journal editors: the need for a full description of laboratory methods and specimen handling in clinical study reports.
PubMed Identifier: 22452379
author list: Rifai N, Annesley TM, Berg JP, Brugnara C, Delvin E, Lamb EJ, Ness PM, Plebani M, Wick MR, Wu A
published in: Transfusion
information resource reference: An appeal to medical journal editors: the need for a full description of laboratory methods and specimen handling in clinical study reports. Transfusion. 2012 Jun; 52(6):e17-9.
journal title abbreviation: Transfusion
publication date: 2012-03-27T00:00:00
year: 2012
type: Academic Article
type: Article
type: Document
type: Information Resource

An algorithm using reticulocyte hemoglobin content (CHr) measurement in screening adolescents for iron deficiency.
PubMed Identifier: 15909357
author list: Stoffman N, Brugnara C, Woods ER
published in: The Journal of adolescent health : official publication of the Society for Adolescent Medicine
information resource reference: An algorithm using reticulocyte hemoglobin content (CHr) measurement in screening adolescents for iron deficiency. J Adolesc Health. 2005 Jun; 36(6):529.
journal title abbreviation: J Adolesc Health
publication date: 2005-06-01T00:00:00
year: 2005
type: Academic Article
type: Article
type: Document
type: Information Resource

Stimulation of human erythrocyte K-Cl cotransport and protein phosphatase type 2A by n-ethylmaleimide: role of intracellular Mg++.
PubMed Identifier: 11003690
author list: Bize I, Güvenç B, Buchbinder G, Brugnara C
published in: The Journal of membrane biology
information resource reference: Stimulation of human erythrocyte K-Cl cotransport and protein phosphatase type 2A by n-ethylmaleimide: role of intracellular Mg++. J Membr Biol. 2000 Sep 15; 177(2):159-68.
journal title abbreviation: J Membr Biol
publication date: 2000-09-15T00:00:00
year: 2000
type: Academic Article
type: Article
type: Document
type: Information Resource

Novel therapies for prevention of erythrocyte dehydration in sickle cell anemia.
PubMed Identifier: 12819792
author list: Brugnara C, De Franceschi L, Bennekou P, Alper SL, Christophersen P
published in: Drug news & perspectives
information resource reference: Novel therapies for prevention of erythrocyte dehydration in sickle cell anemia. Drug News Perspect. 2001 May; 14(4):208-20.
journal title abbreviation: Drug News Perspect
publication date: 2001-05-01T00:00:00
year: 2001
type: Academic Article
type: Article
type: Document
type: Information Resource

Mitochondrial Atpif1 regulates haem synthesis in developing erythroblasts.
PubMed Identifier: 23135403
author list: Shah DI, Takahashi-Makise N, Cooney JD, Li L, Schultz IJ, Pierce EL, Narla A, Seguin A, Hattangadi SM, Medlock AE, Langer NB, Dailey TA, Hurst SN, Faccenda D, Wiwczar JM, Heggers SK, Vogin G, Chen W, Chen C, Campagna DR, Brugnara C, Zhou Y, Ebert BL, Danial NN, Fleming MD, Ward DM, Campanella M, Dailey HA, Kaplan J, Paw BH
published in: Nature
information resource reference: Mitochondrial Atpif1 regulates haem synthesis in developing erythroblasts. Nature. 2012 Nov 22; 491(7425):608-12.
journal title abbreviation: Nature
publication date: 2012-11-07T00:00:00
year: 2012
type: Academic Article
type: Article
type: Document
type: Information Resource

Membrane polyunsaturated fatty acids and lithium-sodium countertransport in human erythrocytes.
PubMed Identifier: 3613870
author list: Corrocher R, Ferrari S, Bassi A, Guarini P, Bertinato L, Olivieri O, Licia GM, Ruzzenente O, Brugnara C, De Sandre G
published in: Life sciences
information resource reference: Membrane polyunsaturated fatty acids and lithium-sodium countertransport in human erythrocytes. Life Sci. 1987 Aug 31; 41(9):1171-8.
journal title abbreviation: Life Sci
publication date: 1987-08-31T00:00:00
year: 1987
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 11393
type: Authorship
author rank in publication: 4
linked author: Brugnara, Carlo
linked information resource: An economic analysis of anemia prevention during infancy.

An appeal to medical journal editors: the need for a full description of laboratory methods and specimen handling in clinical study reports.
PubMed Identifier: 22302921
author list: Rifai N, Annesley TM, Berg JP, Brugnara C, Delvin E, Lamb EJ, Ness PM, Plebani M, Wick MR, Wu A, Delanghe J
published in: Clinical chemistry
information resource reference: An appeal to medical journal editors: the need for a full description of laboratory methods and specimen handling in clinical study reports. Clin Chem. 2012 Mar; 58(3):483-5.
journal title abbreviation: Clin Chem
publication date: 2012-02-01T00:00:00
year: 2012
type: Academic Article
type: Article
type: Document
type: Information Resource

Missense mutations in the ABCB6 transporter cause dominant familial pseudohyperkalemia.
PubMed Identifier: 23180570
author list: Andolfo I, Alper SL, Delaunay J, Auriemma C, Russo R, Asci R, Esposito MR, Sharma AK, Shmukler BE, Brugnara C, De Franceschi L, Iolascon A
published in: American journal of hematology
information resource reference: Missense mutations in the ABCB6 transporter cause dominant familial pseudohyperkalemia. Am J Hematol. 2013 Jan; 88(1):66-72.
journal title abbreviation: Am J Hematol
publication date: 2012-11-24T00:00:00
year: 2012
type: Academic Article
type: Article
type: Document
type: Information Resource

Iron therapy in the pediatric hemodialysis population.
PubMed Identifier: 15064942
author list: Warady BA, Kausz A, Lerner G, Brewer ED, Chadha V, Brugnara C, Dahl NV, Watkins SL
published in: Pediatric nephrology (Berlin, Germany)
information resource reference: Iron therapy in the pediatric hemodialysis population. Pediatr Nephrol. 2004 Jun; 19(6):655-61.
journal title abbreviation: Pediatr Nephrol
publication date: 2004-04-03T00:00:00
year: 2004
type: Academic Article
type: Article
type: Document
type: Information Resource

Foxo3 is required for the regulation of oxidative stress in erythropoiesis.
PubMed Identifier: 17671650
author list: Marinkovic D, Zhang X, Yalcin S, Luciano JP, Brugnara C, Huber T, Ghaffari S
published in: The Journal of clinical investigation
information resource reference: Foxo3 is required for the regulation of oxidative stress in erythropoiesis. J Clin Invest. 2007 Aug; 117(8):2133-44.
journal title abbreviation: J Clin Invest
publication date: 2007-08-01T00:00:00
year: 2007
type: Academic Article
type: Article
type: Document
type: Information Resource

Phase I study of magnesium pidolate in combination with hydroxycarbamide for children with sickle cell anaemia.
PubMed Identifier: 17991298
author list: Hankins JS, Wynn LW, Brugnara C, Hillery CA, Li CS, Wang WC
published in: British journal of haematology
information resource reference: Phase I study of magnesium pidolate in combination with hydroxycarbamide for children with sickle cell anaemia. Br J Haematol. 2008 Jan; 140(1):80-5.
journal title abbreviation: Br J Haematol
publication date: 2007-11-07T00:00:00
year: 2007
type: Academic Article
type: Article
type: Document
type: Information Resource

Characteristics of the volume- and chloride-dependent K transport in human erythrocytes homozygous for hemoglobin C.
PubMed Identifier: 2810352
author list: Brugnara C
published in: The Journal of membrane biology
information resource reference: Characteristics of the volume- and chloride-dependent K transport in human erythrocytes homozygous for hemoglobin C. J Membr Biol. 1989 Oct; 111(1):69-81.
journal title abbreviation: J Membr Biol
publication date: 1989-10-01T00:00:00
year: 1989
type: Academic Article
type: Article
type: Document
type: Information Resource

[Frequency and sex and age distribution of cardiopathy in arterial hypertension].
PubMed Identifier: 3714063
author list: Corrocher R, Bonfanti F, Steinmayr M, Brugnara C, Bertinato L, De Sandre G
published in: Minerva cardioangiologica
information resource reference: [Frequency and sex and age distribution of cardiopathy in arterial hypertension]. Minerva Cardioangiol. 1986 Mar; 34(3):119-25.
journal title abbreviation: Minerva Cardioangiol
publication date: 1986-03-01T00:00:00
year: 1986
type: Academic Article
type: Article
type: Document
type: Information Resource

Inhibition of red cell Ca(2+)-activated K+ transport by clotrimazole does not take place via imidazoline binding sites.
PubMed Identifier: 7677338
author list: Coupry I, Armsby CC, Alper S, Parini A, Brugnara C
published in: Annals of the New York Academy of Sciences
information resource reference: Inhibition of red cell Ca(2+)-activated K+ transport by clotrimazole does not take place via imidazoline binding sites. Ann N Y Acad Sci. 1995 Jul 12; 763:287-9.
journal title abbreviation: Ann N Y Acad Sci
publication date: 1995-07-12T00:00:00
year: 1995
type: Academic Article
type: Article
type: Document
type: Information Resource

Reticulocyte hemoglobin content (CHr): early indicator of iron deficiency and response to therapy.
PubMed Identifier: 8180408
author list: Brugnara C, Laufer MR, Friedman AJ, Bridges K, Platt O
published in: Blood
information resource reference: Reticulocyte hemoglobin content (CHr): early indicator of iron deficiency and response to therapy. Blood. 1994 May 15; 83(10):3100-1.
journal title abbreviation: Blood
publication date: 1994-05-15T00:00:00
year: 1994
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 115734
type: Authorship
author rank in publication: 2
linked author: Brugnara, Carlo
linked information resource: Formation of dense erythrocytes in SAD mice exposed to chronic hypoxia: evaluation of different therapeutic regimens and of a combination of oral clotrimazole and magnesium therapies.

Authorship 1088386
type: Authorship
author rank in publication: 6
linked author: Brugnara, Carlo
linked information resource: A common functional PIEZO1 deletion allele associates with red blood cell density in sickle cell disease patients.

A common functional PIEZO1 deletion allele associates with red blood cell density in sickle cell disease patients.
PubMed Identifier: 30105803
author list: Ilboudo Y, Bartolucci P, Garrett ME, Ashley-Koch A, Telen M, Brugnara C, Galactéros F, Lettre G
published in: American journal of hematology
information resource reference: A common functional PIEZO1 deletion allele associates with red blood cell density in sickle cell disease patients. Am J Hematol. 2018 11; 93(11):E362-E365.
journal title abbreviation: Am J Hematol
publication date: 2018-09-09T00:00:00
year: 2018
type: Academic Article
type: Article
type: Document
type: Information Resource

Clotrimazole inhibits cell proliferation in vitro and in vivo.
PubMed Identifier: 7585119
author list: Benzaquen LR, Brugnara C, Byers HR, Gatton-Celli S, Halperin JA
published in: Nature medicine
information resource reference: Clotrimazole inhibits cell proliferation in vitro and in vivo. Nat Med. 1995 Jun; 1(6):534-40.
journal title abbreviation: Nat Med
publication date: 1995-06-01T00:00:00
year: 1995
type: Academic Article
type: Article
type: Document
type: Information Resource

Early detection of response to hydroxyurea therapy in patients with sickle cell anemia.
PubMed Identifier: 20854115
author list: Ballas SK, McCarthy WF, Guo N, Brugnara C, Kling G, Bauserman RL, Waclawiw MA
published in: Hemoglobin
information resource reference: Early detection of response to hydroxyurea therapy in patients with sickle cell anemia. Hemoglobin. 2010; 34(5):424-9.
journal title abbreviation: Hemoglobin
publication date: 2010-01-01T00:00:00
year: 2010
type: Academic Article
type: Article
type: Document
type: Information Resource

Full-disclosure in industry-sponsored laboratory medicine research studies: Statement by the Consortium of Laboratory Medicine Journal Editors.
PubMed Identifier: 21351119
author list: Rifai N, Plebani M, Wu A, Brugnara C, Delvin E, Lamb EJ, Ness PM, Wick MR, Berg JP
published in: American journal of hematology
information resource reference: Full-disclosure in industry-sponsored laboratory medicine research studies: Statement by the Consortium of Laboratory Medicine Journal Editors. Am J Hematol. 2011 Mar; 86(3):244.
journal title abbreviation: Am J Hematol
publication date: 2011-03-01T00:00:00
year: 2011
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1091353
type: Authorship
author rank in publication: 6
linked author: Brugnara, Carlo
linked information resource: Genotype-phenotype correlation and risk stratification in a cohort of 123 hereditary stomatocytosis patients.

Genotype-phenotype correlation and risk stratification in a cohort of 123 hereditary stomatocytosis patients.
PubMed Identifier: 30187933
author list: Andolfo I, Russo R, Rosato BE, Manna F, Gambale A, Brugnara C, Iolascon A
published in: American journal of hematology
information resource reference: Genotype-phenotype correlation and risk stratification in a cohort of 123 hereditary stomatocytosis patients. Am J Hematol. 2018 12; 93(12):1509-1517.
journal title abbreviation: Am J Hematol
publication date: 2018-10-02T00:00:00
year: 2018
type: Academic Article
type: Article
type: Document
type: Information Resource

Multiple arterial stenoses in chronic ergot toxicity.
PubMed Identifier: 6419107
author list: Corrocher R, Brugnara C, Maso R, Taddei G, Mezzelani P, De Sandre G
published in: The New England journal of medicine
information resource reference: Multiple arterial stenoses in chronic ergot toxicity. N Engl J Med. 1984 Jan 26; 310(4):261.
journal title abbreviation: N Engl J Med
publication date: 1984-01-26T00:00:00
year: 1984
type: Academic Article
type: Article
type: Document
type: Information Resource

[Relations between renin activity and vascular complications of arterial hypertension].
PubMed Identifier: 7045721
author list: Bonfanti F, Pecci R, Nortilli R, Brugnara C, Corrocher R
published in: Minerva cardioangiologica
information resource reference: [Relations between renin activity and vascular complications of arterial hypertension]. Minerva Cardioangiol. 1982 Mar; 30(3):75-80.
journal title abbreviation: Minerva Cardioangiol
publication date: 1982-03-01T00:00:00
year: 1982
type: Academic Article
type: Article
type: Document
type: Information Resource

Ca(2+)-activated K+ channels of human and rabbit erythrocytes display distinctive patterns of inhibition by venom peptide toxins.
PubMed Identifier: 8531201
author list: Brugnara C, Armsby CC, De Franceschi L, Crest M, Euclaire MF, Alper SL
published in: The Journal of membrane biology
information resource reference: Ca(2+)-activated K+ channels of human and rabbit erythrocytes display distinctive patterns of inhibition by venom peptide toxins. J Membr Biol. 1995 Sep; 147(1):71-82.
journal title abbreviation: J Membr Biol
publication date: 1995-09-01T00:00:00
year: 1995
type: Academic Article
type: Article
type: Document
type: Information Resource

The Li+-Na+ exchange and Na+-K+-Cl- cotransport systems in essential hypertension.
PubMed Identifier: 2824364
author list: Canessa M, Brugnara C, Escobales N
published in: Hypertension (Dallas, Tex. : 1979)
information resource reference: The Li+-Na+ exchange and Na+-K+-Cl- cotransport systems in essential hypertension. Hypertension. 1987 Nov; 10(5 Pt 2):I4-10.
journal title abbreviation: Hypertension
publication date: 1987-11-01T00:00:00
year: 1987
type: Academic Article
type: Article
type: Document
type: Information Resource

Reduced DIDS-sensitive chloride conductance in Ae1-/- mouse erythrocytes.
PubMed Identifier: 18329299
author list: Alper SL, Vandorpe DH, Peters LL, Brugnara C
published in: Blood cells, molecules & diseases
information resource reference: Reduced DIDS-sensitive chloride conductance in Ae1-/- mouse erythrocytes. Blood Cells Mol Dis. 2008 Jul-Aug; 41(1):22-34.
journal title abbreviation: Blood Cells Mol Dis
publication date: 2008-03-10T00:00:00
year: 2008
type: Academic Article
type: Article
type: Document
type: Information Resource

An economic analysis of anemia prevention during infancy.
PubMed Identifier: 18760421
author list: Shaker M, Jenkins P, Ullrich C, Brugnara C, Nghiem BT, Bernstein H
published in: The Journal of pediatrics
information resource reference: An economic analysis of anemia prevention during infancy. J Pediatr. 2009 Jan; 154(1):44-9.
journal title abbreviation: J Pediatr
publication date: 2008-08-29T00:00:00
year: 2008
type: Academic Article
type: Article
type: Document
type: Information Resource

An appeal to medical journal editors: the need for a full description of laboratory methods and specimen handling in clinical study reports.
PubMed Identifier: 22297270
author list: Rifai N, Annesley TM, Berg JP, Brugnara C, Delvin E, Lamb EJ, Ness PM, Plebani M, Wick MR, Wu A
published in: Clinical biochemistry
information resource reference: An appeal to medical journal editors: the need for a full description of laboratory methods and specimen handling in clinical study reports. Clin Biochem. 2012 Feb; 45(3):185-6.
journal title abbreviation: Clin Biochem
publication date: 2012-02-01T00:00:00
year: 2012
type: Academic Article
type: Article
type: Document
type: Information Resource

An appeal to medical journal editors: the need for a full description of laboratory methods and specimen handling in clinical study reports.
PubMed Identifier: 22339367
author list: Rifai N, Annesley TM, Berg JP, Brugnara C, Delvin E, Lamb EJ, Ness PM, Plebani M, Wick MR, Wu A, Delanghe J
published in: Scandinavian journal of clinical and laboratory investigation
information resource reference: An appeal to medical journal editors: the need for a full description of laboratory methods and specimen handling in clinical study reports. Scand J Clin Lab Invest. 2012 Apr; 72(2):89-91.
journal title abbreviation: Scand J Clin Lab Invest
publication date: 2012-02-17T00:00:00
year: 2012
type: Academic Article
type: Article
type: Document
type: Information Resource

An appeal to medical journal editors: the need for a full description of laboratory methods and specimen handling in clinical study reports.
PubMed Identifier: 22410758
author list: Rifai N, Annesley TM, Berg JP, Brugnara C, Delvin E, Lamb EJ, Ness PM, Plebani M, Wick MR, Wu A, Delanghe J
published in: American journal of hematology
information resource reference: An appeal to medical journal editors: the need for a full description of laboratory methods and specimen handling in clinical study reports. Am J Hematol. 2012 Apr; 87(4):347-8.
journal title abbreviation: Am J Hematol
publication date: 2012-04-01T00:00:00
year: 2012
type: Academic Article
type: Article
type: Document
type: Information Resource

Modes of operation and variable stoichiometry of the furosemide- sensitive Na and K fluxes in human red cells.
PubMed Identifier: 3950574
author list: Canessa M, Brugnara C, Cusi D, Tosteson DC
published in: The Journal of general physiology
information resource reference: Modes of operation and variable stoichiometry of the furosemide- sensitive Na and K fluxes in human red cells. J Gen Physiol. 1986 Jan; 87(1):113-42.
journal title abbreviation: J Gen Physiol
publication date: 1986-01-01T00:00:00
year: 1986
type: Academic Article
type: Article
type: Document
type: Information Resource

The regulation of Na-K cotransport system and essential hypertension.
PubMed Identifier: 3999644
author list: Canessa M, Brugnara C
published in: Klinische Wochenschrift
information resource reference: The regulation of Na-K cotransport system and essential hypertension. Klin Wochenschr. 1985; 63 Suppl 3:52-4.
journal title abbreviation: Klin Wochenschr
publication date: 1985-01-01T00:00:00
year: 1985
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1095853
type: Authorship
author rank in publication: 11
linked author: Brugnara, Carlo
linked information resource: Erythrocytes lacking the Langereis blood group protein ABCB6 are resistant to the malaria parasite Plasmodium falciparum.

Erythrocytes lacking the Langereis blood group protein ABCB6 are resistant to the malaria parasite Plasmodium falciparum.
PubMed Identifier: 30271928
author list: Egan ES, Weekes MP, Kanjee U, Manzo J, Srinivasan A, Lomas-Francis C, Westhoff C, Takahashi J, Tanaka M, Watanabe S, Brugnara C, Gygi SP, Tani Y, Duraisingh MT
published in: Communications biology
information resource reference: Erythrocytes lacking the Langereis blood group protein ABCB6 are resistant to the malaria parasite Plasmodium falciparum. Commun Biol. 2018; 1:45.
journal title abbreviation: Commun Biol
publication date: 2018-05-03T00:00:00
year: 2018
type: Academic Article
type: Article
type: Document
type: Information Resource

Automated flow cytometric analysis of blood cells in cerebrospinal fluid: analytic performance.
PubMed Identifier: 15151209
author list: Aune MW, Becker JL, Brugnara C, Canfield W, Dorfman DM, Fiehn W, Fischer G, Fitzpatrick P, Flaming TH, Henriksen HK, Kunicka JE, Lackner KJ, Minchello E, Mullenix PA, Myers M, Petersen A, Ternstrom W, Wilson SJ
published in: American journal of clinical pathology
information resource reference: Automated flow cytometric analysis of blood cells in cerebrospinal fluid: analytic performance. Am J Clin Pathol. 2004 May; 121(5):690-700.
journal title abbreviation: Am J Clin Pathol
publication date: 2004-05-01T00:00:00
year: 2004
type: Academic Article
type: Article
type: Document
type: Information Resource

Effects of subcutaneous recombinant human erythropoietin in normal subjects: development of decreased reticulocyte hemoglobin content and iron-deficient erythropoiesis.
PubMed Identifier: 8195672
author list: Brugnara C, Colella GM, Cremins J, Langley RC, Schneider TJ, Rutherford CJ, Goldberg MA
published in: The Journal of laboratory and clinical medicine
information resource reference: Effects of subcutaneous recombinant human erythropoietin in normal subjects: development of decreased reticulocyte hemoglobin content and iron-deficient erythropoiesis. J Lab Clin Med. 1994 May; 123(5):660-7.
journal title abbreviation: J Lab Clin Med
publication date: 1994-05-01T00:00:00
year: 1994
type: Academic Article
type: Article
type: Document
type: Information Resource

Inhibition of K transport by divalent cations in sickle erythrocytes.
PubMed Identifier: 3676515
author list: Brugnara C, Tosteson DC
published in: Blood
information resource reference: Inhibition of K transport by divalent cations in sickle erythrocytes. Blood. 1987 Dec; 70(6):1810-5.
journal title abbreviation: Blood
publication date: 1987-12-01T00:00:00
year: 1987
type: Academic Article
type: Article
type: Document
type: Information Resource

Bradykinin and vasopressin stimulate Na+-K+-Cl- cotransport in cultured endothelial cells.
PubMed Identifier: 3717330
author list: Brock TA, Brugnara C, Canessa M, Gimbrone MA
published in: The American journal of physiology
information resource reference: Bradykinin and vasopressin stimulate Na+-K+-Cl- cotransport in cultured endothelial cells. Am J Physiol. 1986 Jun; 250(6 Pt 1):C888-95.
journal title abbreviation: Am J Physiol
publication date: 1986-06-01T00:00:00
year: 1986
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 110018
type: Authorship
author rank in publication: 1
linked author: Brugnara, Carlo
linked information resource: Erythrocyte dehydration in pathophysiology and treatment of sickle cell disease.

Removal of erythrocyte membrane iron in vivo ameliorates the pathobiology of murine thalassemia.
PubMed Identifier: 9294111
author list: Browne PV, Shalev O, Kuypers FA, Brugnara C, Solovey A, Mohandas N, Schrier SL, Hebbel RP
published in: The Journal of clinical investigation
information resource reference: Removal of erythrocyte membrane iron in vivo ameliorates the pathobiology of murine thalassemia. J Clin Invest. 1997 Sep 15; 100(6):1459-64.
journal title abbreviation: J Clin Invest
publication date: 1997-09-15T00:00:00
year: 1997
type: Academic Article
type: Article
type: Document
type: Information Resource

Activated protein C concentrate for the treatment of meningococcal endotoxin shock in rabbits.
PubMed Identifier: 9488260
author list: Roback MG, Stack AM, Thompson C, Brugnara C, Schwarz HP, Saladino RA
published in: Shock (Augusta, Ga.)
information resource reference: Activated protein C concentrate for the treatment of meningococcal endotoxin shock in rabbits. Shock. 1998 Feb; 9(2):138-42.
journal title abbreviation: Shock
publication date: 1998-02-01T00:00:00
year: 1998
type: Academic Article
type: Article
type: Document
type: Information Resource

Cation transport in mouse erythrocytes: role of K(+)-Cl- cotransport in regulatory volume decrease.
PubMed Identifier: 7733237
author list: Armsby CC, Brugnara C, Alper SL
published in: The American journal of physiology
information resource reference: Cation transport in mouse erythrocytes: role of K(+)-Cl- cotransport in regulatory volume decrease. Am J Physiol. 1995 Apr; 268(4 Pt 1):C894-902.
journal title abbreviation: Am J Physiol
publication date: 1995-04-01T00:00:00
year: 1995
type: Academic Article
type: Article
type: Document
type: Information Resource

Effect of cell age and phenylhydrazine on the cation transport properties of rabbit erythrocytes.
PubMed Identifier: 8381125
author list: Brugnara C, de Franceschi L
published in: Journal of cellular physiology
information resource reference: Effect of cell age and phenylhydrazine on the cation transport properties of rabbit erythrocytes. J Cell Physiol. 1993 Feb; 154(2):271-80.
journal title abbreviation: J Cell Physiol
publication date: 1993-02-01T00:00:00
year: 1993
type: Academic Article
type: Article
type: Document
type: Information Resource

Automated reticulocyte counting: state of the art and clinical applications in the evaluation of erythropoiesis.
PubMed Identifier: 20666695
author list: Piva E, Brugnara C, Chiandetti L, Plebani M
published in: Clinical chemistry and laboratory medicine
information resource reference: Automated reticulocyte counting: state of the art and clinical applications in the evaluation of erythropoiesis. Clin Chem Lab Med. 2010 Oct; 48(10):1369-80.
journal title abbreviation: Clin Chem Lab Med
publication date: 2010-07-29T00:00:00
year: 2010
type: Academic Article
type: Article
type: Document
type: Information Resource

Lithium-sodium countertransport in erythrocytes of normal and hypertensive subjects. Relationship with age and plasma renin activity.
PubMed Identifier: 6345362
author list: Brugnara C, Corrocher R, Foroni L, Steinmayr M, Bonfanti F, De Sandre G
published in: Hypertension (Dallas, Tex. : 1979)
information resource reference: Lithium-sodium countertransport in erythrocytes of normal and hypertensive subjects. Relationship with age and plasma renin activity. Hypertension. 1983 Jul-Aug; 5(4):529-34.
journal title abbreviation: Hypertension
publication date: 1983-07-01T00:00:00
year: 1983
type: Academic Article
type: Article
type: Document
type: Information Resource

Automated reticulocyte counting and measurement of reticulocyte cellular indices. Evaluation of the Miles H*3 blood analyzer.
PubMed Identifier: 7942628
author list: Brugnara C, Hipp MJ, Irving PJ, Lathrop H, Lee PA, Minchello EM, Winkelman J
published in: American journal of clinical pathology
information resource reference: Automated reticulocyte counting and measurement of reticulocyte cellular indices. Evaluation of the Miles H*3 blood analyzer. Am J Clin Pathol. 1994 Nov; 102(5):623-32.
journal title abbreviation: Am J Clin Pathol
publication date: 1994-11-01T00:00:00
year: 1994
type: Academic Article
type: Article
type: Document
type: Information Resource

Management training for pathology residents. II. Experience with a focused curriculum.
PubMed Identifier: 8178761
author list: Winkelman JW, Brugnara C
published in: American journal of clinical pathology
information resource reference: Management training for pathology residents. II. Experience with a focused curriculum. Am J Clin Pathol. 1994 May; 101(5):564-8.
journal title abbreviation: Am J Clin Pathol
publication date: 1994-05-01T00:00:00
year: 1994
type: Academic Article
type: Article
type: Document
type: Information Resource

Duplication of 10 nucleotides in the erythroid band 3 (AE1) gene in a kindred with hereditary spherocytosis and band 3 protein deficiency (band 3PRAGUE).
PubMed Identifier: 8282779
author list: Jarolim P, Rubin HL, Liu SC, Cho MR, Brabec V, Derick LH, Yi SJ, Saad ST, Alper S, Brugnara C
published in: The Journal of clinical investigation
information resource reference: Duplication of 10 nucleotides in the erythroid band 3 (AE1) gene in a kindred with hereditary spherocytosis and band 3 protein deficiency (band 3PRAGUE). J Clin Invest. 1994 Jan; 93(1):121-30.
journal title abbreviation: J Clin Invest
publication date: 1994-01-01T00:00:00
year: 1994
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1110677
type: Authorship
author rank in publication: 17
linked author: Brugnara, Carlo
linked information resource: Resolution of sickle cell disease-associated inflammation and tissue damage with 17R-resolvin D1.

Resolution of sickle cell disease-associated inflammation and tissue damage with 17R-resolvin D1.
PubMed Identifier: 30404812
author list: Matte A, Recchiuti A, Federti E, Koehl B, Mintz T, El Nemer W, Tharaux PL, Brousse V, Andolfo I, Lamolinara A, Weinberg O, Siciliano A, Norris PC, Riley IR, Iolascon A, Serhan CN, Brugnara C, De Franceschi L
published in: Blood
information resource reference: Resolution of sickle cell disease-associated inflammation and tissue damage with 17R-resolvin D1. Blood. 2019 01 17; 133(3):252-265.
journal title abbreviation: Blood
publication date: 2018-11-07T00:00:00
year: 2018
type: Academic Article
type: Article
type: Document
type: Information Resource

Treatment with oral clotrimazole blocks Ca(2+)-activated K+ transport and reverses erythrocyte dehydration in transgenic SAD mice. A model for therapy of sickle cell disease.
PubMed Identifier: 7512989
author list: De Franceschi L, Saadane N, Trudel M, Alper SL, Brugnara C, Beuzard Y
published in: The Journal of clinical investigation
information resource reference: Treatment with oral clotrimazole blocks Ca(2+)-activated K+ transport and reverses erythrocyte dehydration in transgenic SAD mice. A model for therapy of sickle cell disease. J Clin Invest. 1994 Apr; 93(4):1670-6.
journal title abbreviation: J Clin Invest
publication date: 1994-04-01T00:00:00
year: 1994
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1112605
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author rank in publication: 2
linked author: Brugnara, Carlo
linked information resource: Shape oscillations of single blood drops: applications to human blood and sickle cell disease.

Shape oscillations of single blood drops: applications to human blood and sickle cell disease.
PubMed Identifier: 30429489
author list: Hosseinzadeh VA, Brugnara C, Holt RG
published in: Scientific reports
information resource reference: Shape oscillations of single blood drops: applications to human blood and sickle cell disease. Sci Rep. 2018 11 14; 8(1):16794.
journal title abbreviation: Sci Rep
publication date: 2018-11-14T00:00:00
year: 2018
type: Academic Article
type: Article
type: Document
type: Information Resource

Sickle cell disease: from membrane pathophysiology to novel therapies for prevention of erythrocyte dehydration.
PubMed Identifier: 14663274
author list: Brugnara C
published in: Journal of pediatric hematology/oncology
information resource reference: Sickle cell disease: from membrane pathophysiology to novel therapies for prevention of erythrocyte dehydration. J Pediatr Hematol Oncol. 2003 Dec; 25(12):927-33.
journal title abbreviation: J Pediatr Hematol Oncol
publication date: 2003-12-01T00:00:00
year: 2003
type: Academic Article
type: Article
type: Document
type: Information Resource

Protein phosphatase 1alpha is tyrosine-phosphorylated and inactivated by peroxynitrite in erythrocytes through the src family kinase fgr.
PubMed Identifier: 15917191
author list: Mallozzi C, De Franceschi L, Brugnara C, Di Stasi AM
published in: Free radical biology & medicine
information resource reference: Protein phosphatase 1alpha is tyrosine-phosphorylated and inactivated by peroxynitrite in erythrocytes through the src family kinase fgr. Free Radic Biol Med. 2005 Jun 15; 38(12):1625-36.
journal title abbreviation: Free Radic Biol Med
publication date: 2005-03-25T00:00:00
year: 2005
type: Academic Article
type: Article
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Regulation of K-Cl cotransport by protein phosphatase 1alpha in mouse erythrocytes.
PubMed Identifier: 16283202
author list: De Franceschi L, Villa-Moruzzi E, Biondani A, Siciliano A, Brugnara C, Alper SL, Lowell CA, Berton G
published in: Pflugers Archiv : European journal of physiology
information resource reference: Regulation of K-Cl cotransport by protein phosphatase 1alpha in mouse erythrocytes. Pflugers Arch. 2006 Mar; 451(6):760-8.
journal title abbreviation: Pflugers Arch
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type: Academic Article
type: Article
type: Document
type: Information Resource

A high-performance liquid chromatographic assay for the determination of itraconazole concentration using solid-phase extraction and small sample volume.
PubMed Identifier: 8585117
author list: Rifai N, Sakamoto M, Platt O, Brugnara C
published in: Therapeutic drug monitoring
information resource reference: A high-performance liquid chromatographic assay for the determination of itraconazole concentration using solid-phase extraction and small sample volume. Ther Drug Monit. 1995 Oct; 17(5):522-5.
journal title abbreviation: Ther Drug Monit
publication date: 1995-10-01T00:00:00
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type: Academic Article
type: Article
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Cell volume, K transport, and cell density in human erythrocytes.
PubMed Identifier: 3826356
author list: Brugnara C, Tosteson DC
published in: The American journal of physiology
information resource reference: Cell volume, K transport, and cell density in human erythrocytes. Am J Physiol. 1987 Mar; 252(3 Pt 1):C269-76.
journal title abbreviation: Am J Physiol
publication date: 1987-03-01T00:00:00
year: 1987
type: Academic Article
type: Article
type: Document
type: Information Resource

Full disclosure in industry-sponsored laboratory medicine research studies: Statement by the Consortium of Laboratory Medicine Journal Editors.
PubMed Identifier: 21183162
author list: Rifai N, Plebani M, Wu AH, Brugnara C, Delvin E, Lamb EJ, Ness PM, Wick MR, Berg JP
published in: Clinical biochemistry
information resource reference: Full disclosure in industry-sponsored laboratory medicine research studies: Statement by the Consortium of Laboratory Medicine Journal Editors. Clin Biochem. 2011 Feb; 44(2-3):149-50.
journal title abbreviation: Clin Biochem
publication date: 2010-12-22T00:00:00
year: 2010
type: Academic Article
type: Article
type: Document
type: Information Resource

Properties of K+ transport in resealed human erythrocyte ghosts.
PubMed Identifier: 3421317
author list: Brugnara C, Van Ha T, Tosteson DC
published in: The American journal of physiology
information resource reference: Properties of K+ transport in resealed human erythrocyte ghosts. Am J Physiol. 1988 Sep; 255(3 Pt 1):C346-56.
journal title abbreviation: Am J Physiol
publication date: 1988-09-01T00:00:00
year: 1988
type: Academic Article
type: Article
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A new therapeutic approach for sickle cell disease. Blockade of the red cell Ca(2+)-activated K+ channel by clotrimazole.
PubMed Identifier: 7677336
author list: Brugnara C, De Franceschi L, Armsby CC, Saadane N, Trudel M, Beuzard Y, Rittenhouse A, Rifai N, Platt O, Alper SL
published in: Annals of the New York Academy of Sciences
information resource reference: A new therapeutic approach for sickle cell disease. Blockade of the red cell Ca(2+)-activated K+ channel by clotrimazole. Ann N Y Acad Sci. 1995 Jul 12; 763:262-71.
journal title abbreviation: Ann N Y Acad Sci
publication date: 1995-07-12T00:00:00
year: 1995
type: Academic Article
type: Article
type: Document
type: Information Resource

A novel method utilising markers of altered erythropoiesis for the detection of recombinant human erythropoietin abuse in athletes.
PubMed Identifier: 10870111
author list: Parisotto R, Gore CJ, Emslie KR, Ashenden MJ, Brugnara C, Howe C, Martin DT, Trout GJ, Hahn AG
published in: Haematologica
information resource reference: A novel method utilising markers of altered erythropoiesis for the detection of recombinant human erythropoietin abuse in athletes. Haematologica. 2000 Jun; 85(6):564-72.
journal title abbreviation: Haematologica
publication date: 2000-06-01T00:00:00
year: 2000
type: Academic Article
type: Article
type: Document
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In vivo reduction of erythrocyte oxidant stress in a murine model of beta-thalassemia.
PubMed Identifier: 15531450
author list: de Franceschi L, Turrini F, Honczarenko M, Ayi K, Rivera A, Fleming MD, Law T, Mannu F, Kuypers FA, Bast A, van der Vijgh WJ, Brugnara C
published in: Haematologica
information resource reference: In vivo reduction of erythrocyte oxidant stress in a murine model of beta-thalassemia. Haematologica. 2004 Nov; 89(11):1287-98.
journal title abbreviation: Haematologica
publication date: 2004-11-01T00:00:00
year: 2004
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 108253
type: Authorship
author rank in publication: 1
linked author: Brugnara, Carlo
linked information resource: Properties of K+ transport in resealed human erythrocyte ghosts.

The effects of hydroxycarbamide and magnesium on haemoglobin SC disease: results of the multi-centre CHAMPS trial.
PubMed Identifier: 21275961
author list: Wang W, Brugnara C, Snyder C, Wynn L, Rogers Z, Kalinyak K, Brown C, Qureshi A, Bigelow C, Neumayr L, Smith-Whitley K, Chui DH, Delahunty M, Woolson R, Steinberg M, Telen M, Kesler K
published in: British journal of haematology
information resource reference: The effects of hydroxycarbamide and magnesium on haemoglobin SC disease: results of the multi-centre CHAMPS trial. Br J Haematol. 2011 Mar; 152(6):771-6.
journal title abbreviation: Br J Haematol
publication date: 2011-01-31T00:00:00
year: 2011
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type: Article
type: Document
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Authorship 1127771
type: Authorship
author rank in publication: 3
linked author: Brugnara, Carlo
linked information resource: Heritability of fetal hemoglobin, white cell count, and other clinical traits from a sickle cell disease family cohort.

Heritability of fetal hemoglobin, white cell count, and other clinical traits from a sickle cell disease family cohort.
PubMed Identifier: 30680775
author list: Bao EL, Lareau CA, Brugnara C, Fulcher IR, Barau C, Moutereau S, Habibi A, Badaoui B, Berkenou J, Bartolucci P, Galactéros F, Platt OS, Mahaney M, Sankaran VG
published in: American journal of hematology
information resource reference: Heritability of fetal hemoglobin, white cell count, and other clinical traits from a sickle cell disease family cohort. Am J Hematol. 2019 05; 94(5):522-527.
journal title abbreviation: Am J Hematol
publication date: 2019-02-06T00:00:00
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Anemia, Iron-Deficiency
MeSH DescriptorUI: D018798
MeSH semantic group name: Disorders
number of authors: 211
number of publications: 410
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Symporters
MeSH DescriptorUI: D027981
MeSH semantic group name: Chemicals & Drugs
number of authors: 196
number of publications: 380
uniqueness weight: 0.797199
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Erythrocytes
MeSH DescriptorUI: D004912
MeSH semantic group name: Anatomy
number of authors: 817
number of publications: 2391
uniqueness weight: 0.512382
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Highly efficient therapeutic gene editing of human hematopoietic stem cells.
PubMed Identifier: 30911135
author list: Wu Y, Zeng J, Roscoe BP, Liu P, Yao Q, Lazzarotto CR, Clement K, Cole MA, Luk K, Baricordi C, Shen AH, Ren C, Esrick EB, Manis JP, Dorfman DM, Williams DA, Biffi A, Brugnara C, Biasco L, Brendel C, Pinello L, Tsai SQ, Wolfe SA, Bauer DE
published in: Nature medicine
information resource reference: Highly efficient therapeutic gene editing of human hematopoietic stem cells. Nat Med. 2019 May; 25(5):776-783.
journal title abbreviation: Nat Med
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Authorship 1140623
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linked author: Brugnara, Carlo
linked information resource: Highly efficient therapeutic gene editing of human hematopoietic stem cells.

Authorship 117895
type: Authorship
author rank in publication: 3
linked author: Brugnara, Carlo
linked information resource: Sulfhydryl oxidation and activation of red cell K(+)-Cl- cotransport in the transgenic SAD mouse.

Authorship 1144196
type: Authorship
author rank in publication: 5
linked author: Brugnara, Carlo
linked information resource: Increased Red Cell KCNN4 Activity in Sporadic Hereditary Xerocytosis Associated With Enhanced Single Channel Pressure Sensitivity of PIEZO1 Mutant V598M.

Increased Red Cell KCNN4 Activity in Sporadic Hereditary Xerocytosis Associated With Enhanced Single Channel Pressure Sensitivity of PIEZO1 Mutant V598M.
PubMed Identifier: 30887001
author list: Gnanasambandam R, Rivera A, Vandorpe DH, Shmukler BE, Brugnara C, Snyder LM, Andolfo I, Iolascon A, Silveira PA, Hamerschlak N, Gottlieb P, Alper SL
published in: HemaSphere
information resource reference: Increased Red Cell KCNN4 Activity in Sporadic Hereditary Xerocytosis Associated With Enhanced Single Channel Pressure Sensitivity of PIEZO1 Mutant V598M. Hemasphere. 2018 10; 2(5):e55.
journal title abbreviation: Hemasphere
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Anemia, Sickle Cell
MeSH DescriptorUI: D000755
MeSH semantic group name: Disorders
number of authors: 412
number of publications: 1108
uniqueness weight: 0.533329
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Reticulocytes
MeSH DescriptorUI: D012156
MeSH semantic group name: Anatomy
number of authors: 119
number of publications: 273
uniqueness weight: 0.916454
type: Concept

Emeritus
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Immunology and Infectious Diseases
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Malaria/Wirth
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Medicine
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Pathology
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Pediatrics
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Hematology/Oncology
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Nephrology
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Beth Israel Deaconess Medical Center
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Brigham and Women's Hospital
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Boston Children's Hospital
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Harvard Medical School
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Harvard T.H. Chan School of Public Health
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Authorship 1154843
type: Authorship
author rank in publication: 2
linked author: Brugnara, Carlo
linked information resource: Monitoring of blood coagulation with non-contact drop oscillation rheometry.

Authorship 1154655
type: Authorship
author rank in publication: 12
linked author: Brugnara, Carlo
linked information resource: Erythrocyte ion content and dehydration modulate maximal Gardos channel activity in KCNN4 V282M/+ hereditary xerocytosis red cells.

Monitoring of blood coagulation with non-contact drop oscillation rheometry.
PubMed Identifier: 31099102
author list: Ansari Hosseinzadeh V, Brugnara C, Emani S, Khismatullin D, Holt RG
published in: Journal of thrombosis and haemostasis : JTH
information resource reference: Monitoring of blood coagulation with non-contact drop oscillation rheometry. J Thromb Haemost. 2019 08; 17(8):1345-1353.
journal title abbreviation: J Thromb Haemost
publication date: 2019-06-06T00:00:00
year: 2019
type: Academic Article
type: Article
type: Document
type: Information Resource

Erythrocyte ion content and dehydration modulate maximal Gardos channel activity in KCNN4 V282M/+ hereditary xerocytosis red cells.
PubMed Identifier: 31091145
author list: Rivera A, Vandorpe DH, Shmukler BE, Andolfo I, Iolascon A, Archer NM, Shabani E, Auerbach M, Hamerschlak N, Morton J, Wohlgemuth JG, Brugnara C, Snyder LM, Alper SL
published in: American journal of physiology. Cell physiology
information resource reference: Erythrocyte ion content and dehydration modulate maximal Gardos channel activity in KCNN4 V282M/+ hereditary xerocytosis red cells. Am J Physiol Cell Physiol. 2019 08 01; 317(2):C287-C302.
journal title abbreviation: Am J Physiol Cell Physiol
publication date: 2019-05-15T00:00:00
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type: Academic Article
type: Article
type: Document
type: Information Resource

Duraisingh, Manoj
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Schmidt, Birgitta
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Vandorpe, David
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Lidov, Hart
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Fleming, Mark
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Alper, Seth
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Platt, Orah
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Cowman, Alan
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Rifai, Nader
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Kozakewich, Harry
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Heeney, Matthew
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Rivera, Alicia
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McAdam, Alexander
eCommons Login: AJM3
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Authorship 1177867
type: Authorship
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linked information resource: Combined genetic disruption of K-Cl cotransporters and Gardos channel KCNN4 rescues erythrocyte dehydration in the SAD mouse model of sickle cell disease.

Combined genetic disruption of K-Cl cotransporters and Gardos channel KCNN4 rescues erythrocyte dehydration in the SAD mouse model of sickle cell disease.
PubMed Identifier: 31352162
author list: Shmukler BE, Rivera A, Bhargava P, Nishimura K, Hsu A, Kim EH, Trudel M, Rust MB, Hubner CA, Brugnara C, Alper SL
published in: Blood cells, molecules & diseases
information resource reference: Combined genetic disruption of K-Cl cotransporters and Gardos channel KCNN4 rescues erythrocyte dehydration in the SAD mouse model of sickle cell disease. Blood Cells Mol Dis. 2019 11; 79:102346.
journal title abbreviation: Blood Cells Mol Dis
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Authorship 150241
type: Authorship
author rank in publication: 14
linked author: Brugnara, Carlo
linked information resource: Oxygen gas-filled microparticles provide intravenous oxygen delivery.

Authorship 145618
type: Authorship
author rank in publication: 7
linked author: Brugnara, Carlo
linked information resource: A dominant negative mutant of the KCC1 K-Cl cotransporter: both N- and C-terminal cytoplasmic domains are required for K-Cl cotransport activity.

Authorship 154445
type: Authorship
author rank in publication: 3
linked author: Brugnara, Carlo
linked information resource: Endothelins activate Ca(2+)-gated K(+) channels via endothelin B receptors in CD-1 mouse erythrocytes.

Authorship 1196435
type: Authorship
author rank in publication: 18
linked author: Brugnara, Carlo
linked information resource: Bitopertin, a selective oral GLYT1 inhibitor, improves anemia in a mouse model of ß-thalassemia.

Bitopertin, a selective oral GLYT1 inhibitor, improves anemia in a mouse model of ß-thalassemia.
PubMed Identifier: 31593554
author list: Matte A, Federti E, Winter M, Koerner A, Harmeier A, Mazer N, Tomka T, Di Paolo ML, De Falco L, Andolfo I, Beneduce E, Iolascon A, Macias-Garcia A, Chen JJ, Janin A, Lebouef C, Turrini F, Brugnara C, De Franceschi L
published in: JCI insight
information resource reference: Bitopertin, a selective oral GLYT1 inhibitor, improves anemia in a mouse model of ß-thalassemia. JCI Insight. 2019 11 14; 4(22).
journal title abbreviation: JCI Insight
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type: Document
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Authorship 11098
type: Authorship
author rank in publication: 6
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linked information resource: Thawing fresh frozen plasma in a microwave oven. A comparison with thawing in a 37 degrees C waterbath.

Authorship 166682
type: Authorship
author rank in publication: 1
linked author: Brugnara, Carlo
linked information resource: Effect of cell age and phenylhydrazine on the cation transport properties of rabbit erythrocytes.

Authorship 152795
type: Authorship
author rank in publication: 13
linked author: Brugnara, Carlo
linked information resource: Autosomal dominant distal renal tubular acidosis is associated in three families with heterozygosity for the R589H mutation in the AE1 (band 3) Cl-/HCO3- exchanger.

Authorship 141526
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author rank in publication: 6
linked author: Brugnara, Carlo
linked information resource: ICA-17043, a novel Gardos channel blocker, prevents sickled red blood cell dehydration in vitro and in vivo in SAD mice.

Authorship 1204774
type: Authorship
author rank in publication: 3
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linked information resource: Knowledge of Blood Group Decreases von Willebrand Factor Panel Testing in Children.

Knowledge of Blood Group Decreases von Willebrand Factor Panel Testing in Children.
PubMed Identifier: 31723732
author list: Archer NM, Forbes PW, Brugnara C
published in: HemaSphere
information resource reference: Knowledge of Blood Group Decreases von Willebrand Factor Panel Testing in Children. Hemasphere. 2017 12; 1(1):e3.
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Instructor in Medicine
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Authorship 123903
type: Authorship
author rank in publication: 1
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linked information resource: Membrane transport of Na and K and cell dehydration in sickle erythrocytes.

Authorship 129214
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author rank in publication: 5
linked author: Brugnara, Carlo
linked information resource: Ineffective erythropoiesis in Stat5a(-/-)5b(-/-) mice due to decreased survival of early erythroblasts.

Authorship 1212068
type: Authorship
author rank in publication: 13
linked author: Brugnara, Carlo
linked information resource: Genetic disruption of KCC cotransporters in a mouse model of thalassemia intermedia.

Genetic disruption of KCC cotransporters in a mouse model of thalassemia intermedia.
PubMed Identifier: 31835175
author list: Shmukler BE, Rivera A, Bhargava P, Nishimura K, Kim EH, Hsu A, Wohlgemuth JG, Morton J, Snyder LM, De Franceschi L, Rust MB, Hubner CA, Brugnara C, Alper SL
published in: Blood cells, molecules & diseases
information resource reference: Genetic disruption of KCC cotransporters in a mouse model of thalassemia intermedia. Blood Cells Mol Dis. 2020 03; 81:102389.
journal title abbreviation: Blood Cells Mol Dis
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type: Academic Article
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type: Document
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Authorship 129291
type: Authorship
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linked author: Brugnara, Carlo
linked information resource: [Multiple renal arteries and arterial hypertension: a review of 337 renal arteriography cases].

Authorship 1218546
type: Authorship
author rank in publication: 10
linked author: Brugnara, Carlo
linked information resource: https://connects.catalyst.harvard.edu/Profiles/profile/143664074

https://connects.catalyst.harvard.edu/Profiles/profile/143664074
PubMed Identifier: 31931456
author list: Shmukler BE, Rivera A, Bhargava P, Nishimura K, Hsu A, Kim EH, Trudel M, Rust MB, Hubner CA, Brugnara C, Alper SL
published in: Blood cells, molecules & diseases
information resource reference: Corrigendum to "Combined genetic disruption of K-Cl cotransporters and Gardos channel KCNN4 rescues erythrocyte dehydration in the SAD mouse model of sickle cell disease" [Blood Cells Mol. Dis. (2019) start page-end page not yet assigned] https://doi.org/10.1016/j.bcmd.2019.102346. Blood Cells Mol Dis. 2020 Mar; 81:102390.
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label: Corrigendum to "Combined genetic disruption of K-Cl cotransporters and Gardos channel KCNN4 rescues erythrocyte dehydration in the SAD mouse model of sickle cell disease" [Blood Cells Mol. Dis. (2019) start page-end page not yet assigned] https://doi.org/10.1016/j.bcmd.2019.102346.

Authorship 1227861
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author rank in publication: 2
linked author: Brugnara, Carlo
linked information resource: Non-Parametric Combined Reference Regions and Prediction of Clinical Risk.

Non-Parametric Combined Reference Regions and Prediction of Clinical Risk.
PubMed Identifier: 32040586
author list: Malka R, Brugnara C, Cialic R, Higgins JM
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information resource reference: Non-Parametric Combined Reference Regions and Prediction of Clinical Risk. Clin Chem. 2020 02 01; 66(2):363-372.
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publication date: 2020-02-01T00:00:00
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Authorship 12185
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author rank in publication: 4
linked author: Brugnara, Carlo
linked information resource: [Relations between renin activity and vascular complications of arterial hypertension].

Authorship 1237347
type: Authorship
author rank in publication: 7
linked author: Brugnara, Carlo
linked information resource: Association of Blood Type With Postsurgical Mucosal Bleeding in Pediatric Patients Undergoing Tonsillectomy With or Without Adenoidectomy.

Association of Blood Type With Postsurgical Mucosal Bleeding in Pediatric Patients Undergoing Tonsillectomy With or Without Adenoidectomy.
PubMed Identifier: 32232448
author list: Archer NM, Forbes PW, Dargie J, Manganella J, Licameli GR, Kenna MA, Brugnara C
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Authorship 133279
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author rank in publication: 1
linked author: Brugnara, Carlo
linked information resource: Role of chloride in potassium transport through a K-Cl cotransport system in human red blood cells.

Authorship 192377
type: Authorship
author rank in publication: 1
linked author: Brugnara, Carlo
linked information resource: Electrolyte composition and equilibrium in hemoglobin CC red blood cells.

Authorship 175644
type: Authorship
author rank in publication: 10
linked author: Brugnara, Carlo
linked information resource: Pediatric laboratory medicine: current challenges and future opportunities.

Authorship 18323
type: Authorship
author rank in publication: 4
linked author: Brugnara, Carlo
linked information resource: An appeal to medical journal editors: the need for a full description of laboratory methods and specimen handling in clinical study reports.

Authorship 129001
type: Authorship
author rank in publication: 2
linked author: Brugnara, Carlo
linked information resource: Automated reticulocyte counting: state of the art and clinical applications in the evaluation of erythropoiesis.

Authorship 1256287
type: Authorship
author rank in publication: 5
linked author: Brugnara, Carlo
linked information resource: Pediatric hematology normal ranges derived from pediatric primary care patients.

Pediatric hematology normal ranges derived from pediatric primary care patients.
PubMed Identifier: 32530536
author list: Staffa SJ, Joerger JD, Henry E, Christensen RD, Brugnara C, Zurakowski D
published in: American journal of hematology
information resource reference: Pediatric hematology normal ranges derived from pediatric primary care patients. Am J Hematol. 2020 Oct; 95(10):E255-E257.
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Authorship 136441
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author rank in publication: 2
linked author: Brugnara, Carlo
linked information resource: Erythrocyte density in sickle cell syndromes is associated with specific clinical manifestations and hemolysis.

Authorship 161196
type: Authorship
author rank in publication: 3
linked author: Brugnara, Carlo
linked information resource: A multiparameter analysis of sickle erythrocytes in patients undergoing hydroxyurea therapy.

Stowell, Sean
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first name: Sean
last name: Stowell
full name: Sean R. Stowell, M.D.
has faculty rank: Full Professor
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Authorship 141226
type: Authorship
author rank in publication: 1
linked author: Brugnara, Carlo
linked information resource: An immunoassay for human serum hepcidin at last: Ganz klar?

Authorship 1290134
type: Authorship
author rank in publication: 4
linked author: Brugnara, Carlo
linked information resource: Potential causal role of l-glutamine in sickle cell disease painful crises: A Mendelian randomization analysis.

Potential causal role of l-glutamine in sickle cell disease painful crises: A Mendelian randomization analysis.
PubMed Identifier: 32949984
author list: Ilboudo Y, Garrett ME, Bartolucci P, Brugnara C, Clish CB, Hirschhorn JN, Galactéros F, Ashley-Koch AE, Telen MJ, Lettre G
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information resource reference: Potential causal role of l-glutamine in sickle cell disease painful crises: A Mendelian randomization analysis. Blood Cells Mol Dis. 2021 02; 86:102504.
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publication date: 2020-09-10T00:00:00
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Authorship 206667
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author rank in publication: 1
linked author: Brugnara, Carlo
linked information resource: Red blood cell regeneration induced by subcutaneous recombinant erythropoietin: iron-deficient erythropoiesis in iron-replete subjects.

Authorship 200270
type: Authorship
author rank in publication: 4
linked author: Brugnara, Carlo
linked information resource: Use of erythropoiesis stimulating agents and intravenous iron for cancer and treatment-related anaemia: the need for predictors and indicators of effectiveness has not abated.

Authorship 154183
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author rank in publication: 1
linked author: Brugnara, Carlo
linked information resource: Membrane properties of erythrocytes in subjects undergoing multiple blood donations with or without recombinant erythropoietin.

Authorship 1326340
type: Authorship
author rank in publication: 3
linked author: Brugnara, Carlo
linked information resource: Haemoglobin response to senicapoc in patients with sickle cell disease: a re-analysis of the Phase III trial.

Haemoglobin response to senicapoc in patients with sickle cell disease: a re-analysis of the Phase III trial.
PubMed Identifier: 33527340
author list: Ataga KI, Staffa SJ, Brugnara C, Stocker JW
published in: British journal of haematology
information resource reference: Haemoglobin response to senicapoc in patients with sickle cell disease: a re-analysis of the Phase III trial. Br J Haematol. 2021 03; 192(5):e129-e132.
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Authorship 157294
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author rank in publication: 4
linked author: Brugnara, Carlo
linked information resource: Modulation of erythrocyte potassium chloride cotransport, potassium content, and density by dietary magnesium intake in transgenic SAD mouse.

Authorship 1337558
type: Authorship
author rank in publication: 8
linked author: Brugnara, Carlo
linked information resource: Plasmodium vivax infection compromises reticulocyte stability.

Plasmodium vivax infection compromises reticulocyte stability.
PubMed Identifier: 33712609
author list: Clark MA, Kanjee U, Rangel GW, Chery L, Mascarenhas A, Gomes E, Rathod PK, Brugnara C, Ferreira MU, Duraisingh MT
published in: Nature communications
information resource reference: Plasmodium vivax infection compromises reticulocyte stability. Nat Commun. 2021 03 12; 12(1):1629.
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Authorship 1338944
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author rank in publication: 1
linked author: Brugnara, Carlo
linked information resource: Less (Fe) is more (Hb) in SCA.

Less (Fe) is more (Hb) in SCA.
PubMed Identifier: 33734335
author list: Brugnara C
published in: Blood
information resource reference: Less (Fe) is more (Hb) in SCA. Blood. 2021 03 18; 137(11):1446-1447.
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Authorship 145179
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author rank in publication: 7
linked author: Brugnara, Carlo
linked information resource: E2F4 is essential for normal erythrocyte maturation and neonatal viability.

Authorship 1343571
type: Authorship
author rank in publication: 14
linked author: Brugnara, Carlo
linked information resource: Single-cell analysis of FOXP3 deficiencies in humans and mice unmasks intrinsic and extrinsic CD4+ T cell perturbations.

Authorship 1345211
type: Authorship
author rank in publication: 23
linked author: Brugnara, Carlo
linked information resource: The pyruvate kinase activator mitapivat reduces hemolysis and improves anemia in a ß-thalassemia mouse model.

Single-cell analysis of FOXP3 deficiencies in humans and mice unmasks intrinsic and extrinsic CD4+ T cell perturbations.
PubMed Identifier: 33833438
author list: Zemmour D, Charbonnier LM, Leon J, Six E, Keles S, Delville M, Benamar M, Baris S, Zuber J, Chen K, Neven B, Garcia-Lloret MI, Ruemmele FM, Brugnara C, Cerf-Bensussan N, Rieux-Laucat F, Cavazzana M, André I, Chatila TA, Mathis D, Benoist C
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information resource reference: Single-cell analysis of FOXP3 deficiencies in humans and mice unmasks intrinsic and extrinsic CD4+ T cell perturbations. Nat Immunol. 2021 05; 22(5):607-619.
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The pyruvate kinase activator mitapivat reduces hemolysis and improves anemia in a ß-thalassemia mouse model.
PubMed Identifier: 33822774
author list: Matte A, Federti E, Kung C, Kosinski PA, Narayanaswamy R, Russo R, Federico G, Carlomagno F, Desbats MA, Salviati L, Leboeuf C, Valenti MT, Turrini F, Janin A, Yu S, Beneduce E, Ronseaux S, Iatcenko I, Dang L, Ganz T, Jung CL, Iolascon A, Brugnara C, De Franceschi L
published in: The Journal of clinical investigation
information resource reference: The pyruvate kinase activator mitapivat reduces hemolysis and improves anemia in a ß-thalassemia mouse model. J Clin Invest. 2021 05 17; 131(10).
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Authorship 146279
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author rank in publication: 2
linked author: Brugnara, Carlo
linked information resource: Voltage-activated cation transport in human erythrocytes.

Authorship 1351628
type: Authorship
author rank in publication: 13
linked author: Brugnara, Carlo
linked information resource: Haematological effects of oral administration of bitopertin, a glycine transport inhibitor, in patients with non-transfusion-dependent ß-thalassaemia.

Haematological effects of oral administration of bitopertin, a glycine transport inhibitor, in patients with non-transfusion-dependent ß-thalassaemia.
PubMed Identifier: 33931857
author list: Taher AT, Viprakasit V, Cappellini MD, Kraus D, Cech P, Volz D, Winter E, Nave S, Dukart J, Khwaja O, Koerner A, Hermosilla R, Brugnara C
published in: British journal of haematology
information resource reference: Haematological effects of oral administration of bitopertin, a glycine transport inhibitor, in patients with non-transfusion-dependent ß-thalassaemia. Br J Haematol. 2021 07; 194(2):474-477.
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Authorship 1353529
type: Authorship
author rank in publication: 3
linked author: Brugnara, Carlo
linked information resource: Using Reticulocyte Hemoglobin Equivalent as a Marker for Iron Deficiency and Responsiveness to Iron Therapy.

Using Reticulocyte Hemoglobin Equivalent as a Marker for Iron Deficiency and Responsiveness to Iron Therapy.
PubMed Identifier: 33952394
author list: Auerbach M, Staffa SJ, Brugnara C
published in: Mayo Clinic proceedings
information resource reference: Using Reticulocyte Hemoglobin Equivalent as a Marker for Iron Deficiency and Responsiveness to Iron Therapy. Mayo Clin Proc. 2021 06; 96(6):1510-1519.
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Authorship 1360911
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author rank in publication: 9
linked author: Brugnara, Carlo
linked information resource: Dietary ?-3 Fatty Acid Supplementation Improves Murine Sickle Cell Bone Disease and Reprograms Adipogenesis.

Dietary ?-3 Fatty Acid Supplementation Improves Murine Sickle Cell Bone Disease and Reprograms Adipogenesis.
PubMed Identifier: 34070133
author list: Valenti MT, Mattè A, Federti E, Puder M, Anez-Bustillos L, Deiana M, Cheri S, Minoia A, Brugnara C, Di Paolo ML, Dalle Carbonare L, De Franceschi L
published in: Antioxidants (Basel, Switzerland)
information resource reference: Dietary ?-3 Fatty Acid Supplementation Improves Murine Sickle Cell Bone Disease and Reprograms Adipogenesis. Antioxidants (Basel). 2021 May 18; 10(5).
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Authorship 1363091
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author rank in publication: 13
linked author: Brugnara, Carlo
linked information resource: A Grammastola spatulata mechanotoxin-4 (GsMTx4)-sensitive cation channel mediates increased cation permeability in human hereditary spherocytosis of multiple genetic etiologies.

A Grammastola spatulata mechanotoxin-4 (GsMTx4)-sensitive cation channel mediates increased cation permeability in human hereditary spherocytosis of multiple genetic etiologies.
PubMed Identifier: 34109777
author list: Vandorpe DH, Shmukler BE, Ilboudo Y, Bhasin S, Thomas B, Rivera A, Wohlgemuth JG, Dlott JS, Snyder LM, Sieff C, Bhasin M, Lettre G, Brugnara C, Alper SL
published in: Haematologica
information resource reference: A Grammastola spatulata mechanotoxin-4 (GsMTx4)-sensitive cation channel mediates increased cation permeability in human hereditary spherocytosis of multiple genetic etiologies. Haematologica. 2021 10 01; 106(10):2759-2762.
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Authorship 1375171
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author rank in publication: 13
linked author: Brugnara, Carlo
linked information resource: An artificial intelligence-assisted diagnostic platform for rapid near-patient hematology.

An artificial intelligence-assisted diagnostic platform for rapid near-patient hematology.
PubMed Identifier: 34264525
author list: Bachar N, Benbassat D, Brailovsky D, Eshel Y, Glück D, Levner D, Levy S, Pecker S, Yurkovsky E, Zait A, Sever C, Kratz A, Brugnara C
published in: American journal of hematology
information resource reference: An artificial intelligence-assisted diagnostic platform for rapid near-patient hematology. Am J Hematol. 2021 10 01; 96(10):1264-1274.
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type: Information Resource

Authorship 1380353
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author rank in publication: 7
linked author: Brugnara, Carlo
linked information resource: Global genome analysis reveals a vast and dynamic anellovirus landscape within the human virome.

Global genome analysis reveals a vast and dynamic anellovirus landscape within the human virome.
PubMed Identifier: 34320399
author list: Arze CA, Springer S, Dudas G, Patel S, Bhattacharyya A, Swaminathan H, Brugnara C, Delagrave S, Ong T, Kahvejian A, Echelard Y, Weinstein EG, Hajjar RJ, Andersen KG, Yozwiak NL
published in: Cell host & microbe
information resource reference: Global genome analysis reveals a vast and dynamic anellovirus landscape within the human virome. Cell Host Microbe. 2021 Aug 11; 29(8):1305-1315.e6.
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type: Document
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Authorship 1392811
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author rank in publication: 1
linked author: Brugnara, Carlo
linked information resource: Diagnostics with modern genomics.

Diagnostics with modern genomics.
PubMed Identifier: 34536026
author list: Brugnara C
published in: American journal of hematology
information resource reference: Diagnostics with modern genomics. Am J Hematol. 2021 11 01; 96(11):E447.
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publication date: 2021-10-04T00:00:00
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type: Academic Article
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type: Document
type: Information Resource

Authorship 1406494
type: Authorship
author rank in publication: 5
linked author: Brugnara, Carlo
linked information resource: Standardization of reticulocyte counts in the athlete biological passport: A practical update.

Standardization of reticulocyte counts in the athlete biological passport: A practical update.
PubMed Identifier: 34709714
author list: Equey T, Sletten C, Dehnes Y, D'Onofrio G, Brugnara C, Baume N, Aikin R
published in: International journal of laboratory hematology
information resource reference: Standardization of reticulocyte counts in the athlete biological passport: A practical update. Int J Lab Hematol. 2022 Feb; 44(1):112-117.
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publication date: 2021-10-28T00:00:00
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type: Academic Article
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type: Document
type: Information Resource

Authorship 1412520
type: Authorship
author rank in publication: 8
linked author: Brugnara, Carlo
linked information resource: Trpv1 and Trpa1 are not essential for Psickle-like activity in red cells of the SAD mouse model of sickle cell disease.

Trpv1 and Trpa1 are not essential for Psickle-like activity in red cells of the SAD mouse model of sickle cell disease.
PubMed Identifier: 34768199
author list: Vandorpe DH, Rivera A, Shmukler BE, Wohlgemuth JG, Dlott JS, Snyder LM, Trudel M, Brugnara C, Alper SL
published in: Blood cells, molecules & diseases
information resource reference: Trpv1 and Trpa1 are not essential for Psickle-like activity in red cells of the SAD mouse model of sickle cell disease. Blood Cells Mol Dis. 2021 12; 92:102619.
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type: Academic Article
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Authorship 262211
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author rank in publication: 10
linked author: Brugnara, Carlo
linked information resource: Duplication of 10 nucleotides in the erythroid band 3 (AE1) gene in a kindred with hereditary spherocytosis and band 3 protein deficiency (band 3PRAGUE).

Authorship 1436388
type: Authorship
author rank in publication: 8
linked author: Brugnara, Carlo
linked information resource: Erythroid-specific inactivation of Slc12a6/Kcc3 by EpoR promoter-driven Cre expression reduces K-Cl cotransport activity in mouse erythrocytes.

Authorship 1441165
type: Authorship
author rank in publication: 8
linked author: Brugnara, Carlo
linked information resource: Purinergic signaling is essential for full Psickle activation by hypoxia and by normoxic acid pH in mature human sickle red cells and in vitro-differentiated cultured human sickle reticulocytes.

Erythroid-specific inactivation of Slc12a6/Kcc3 by EpoR promoter-driven Cre expression reduces K-Cl cotransport activity in mouse erythrocytes.
PubMed Identifier: 35274823
author list: Shmukler BE, Rivera A, Nishimura K, Hsu A, Wohlgemuth JG, Dlott JS, Michael Snyder L, Brugnara C, Alper SL
published in: Physiological reports
information resource reference: Erythroid-specific inactivation of Slc12a6/Kcc3 by EpoR promoter-driven Cre expression reduces K-Cl cotransport activity in mouse erythrocytes. Physiol Rep. 2022 03; 10(5):e15186.
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Purinergic signaling is essential for full Psickle activation by hypoxia and by normoxic acid pH in mature human sickle red cells and in vitro-differentiated cultured human sickle reticulocytes.
PubMed Identifier: 35169901
author list: Vandorpe DH, Rivera A, Ganter M, Dankwa S, Wohlgemuth JG, Dlott JS, Snyder LM, Brugnara C, Duraisingh M, Alper SL
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information resource reference: Purinergic signaling is essential for full Psickle activation by hypoxia and by normoxic acid pH in mature human sickle red cells and in vitro-differentiated cultured human sickle reticulocytes. Pflugers Arch. 2022 05; 474(5):553-565.
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Authorship 275741
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author rank in publication: 6
linked author: Brugnara, Carlo
linked information resource: Iron therapy in the pediatric hemodialysis population.

Authorship 1446335
type: Authorship
author rank in publication: 11
linked author: Brugnara, Carlo
linked information resource: Commentaries on Viewpoint: Consider iron status when making sex comparisons in human physiology.

Authorship 1447690
type: Authorship
author rank in publication: 1
linked author: Brugnara, Carlo
linked information resource: The Erythrocyte, a Novel Disease-Mediator for COVID-19 Vasculopathy?

Commentaries on Viewpoint: Consider iron status when making sex comparisons in human physiology.
PubMed Identifier: 35274549
author list: Badenhorst CE, Millet GP, Debevec T, Brocherie F, Coates AM, Burr JF, Andersen AB, Bejder J, Gliemann L, Pedlar CR, Brugnara C, Shiffman VJ, Peters CM, Sheel AW, Bruinvels G, Govus AD, Shivgulam ME, Petterson JL, O’Brien MW, Burden RJ, Besson T, Ansdell P, Sánchez-Briones ME
published in: Journal of applied physiology (Bethesda, Md. : 1985)
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publication date: 2022-03-01T00:00:00
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type: Academic Article
type: Article
type: Document
type: Information Resource

The Erythrocyte, a Novel Disease-Mediator for COVID-19 Vasculopathy?
PubMed Identifier: 35411314
author list: Brugnara C
published in: JACC. Basic to translational science
information resource reference: The Erythrocyte, a Novel Disease-Mediator for COVID-19 Vasculopathy? JACC Basic Transl Sci. 2022 Mar; 7(3):205-206.
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type: Academic Article
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type: Document
type: Information Resource

Authorship 317064
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author rank in publication: 9
linked author: Brugnara, Carlo
linked information resource: Reticulocyte parameters as potential discriminators of recombinant human erythropoietin abuse in elite athletes.

Authorship 33470
type: Authorship
author rank in publication: 1
linked author: Brugnara, Carlo
linked information resource: Ion content and transport and the regulation of volume in sickle cells.

Authorship 367460
type: Authorship
author rank in publication: 6
linked author: Brugnara, Carlo
linked information resource: Chemical crosslinking studies with the mouse Kcc1 K-Cl cotransporter.

Authorship 378878
type: Authorship
author rank in publication: 2
linked author: Brugnara, Carlo
linked information resource: Dietary magnesium supplementation ameliorates anemia in a mouse model of beta-thalassemia.

Authorship 381350
type: Authorship
author rank in publication: 4
linked author: Brugnara, Carlo
linked information resource: Activated protein C concentrate for the treatment of meningococcal endotoxin shock in rabbits.

Authorship 382381
type: Authorship
author rank in publication: 4
linked author: Brugnara, Carlo
linked information resource: Full disclosure in industry-sponsored laboratory medicine research studies: Statement by the Consortium of Laboratory Medicine Journal Editors.

Authorship 1465743
type: Authorship
author rank in publication: 9
linked author: Brugnara, Carlo
linked information resource: The erythroid K-Cl cotransport inhibitor [(dihydroindenyl)oxy]acetic acid blocks erythroid Ca2+-activated K+ channel KCNN4.

The erythroid K-Cl cotransport inhibitor [(dihydroindenyl)oxy]acetic acid blocks erythroid Ca2+-activated K+ channel KCNN4.
PubMed Identifier: 35848620
author list: Rivera A, Nasburg JA, Shim H, Shmukler BE, Kitten J, Wohlgemuth JG, Dlott JS, Snyder LM, Brugnara C, Wulff H, Alper SL
published in: American journal of physiology. Cell physiology
information resource reference: The erythroid K-Cl cotransport inhibitor [(dihydroindenyl)oxy]acetic acid blocks erythroid Ca2+-activated K+ channel KCNN4. Am J Physiol Cell Physiol. 2022 09 01; 323(3):C694-C705.
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type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 404002
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author rank in publication: 5
linked author: Brugnara, Carlo
linked information resource: Efficacy of different dosing regimens for recombinant human erythropoietin in a simulated perisurgical setting: the importance of iron availability in optimizing response.

Authorship 1487850
type: Authorship
author rank in publication: 2
linked author: Brugnara, Carlo
linked information resource: HbSC disease: A time for progress.

Authorship 1497815
type: Authorship
author rank in publication: 5
linked author: Brugnara, Carlo
linked information resource: Variation and impact of polygenic hematologic traits in monogenic sickle cell disease.

HbSC disease: A time for progress.
PubMed Identifier: 36073655
author list: Minniti C, Brugnara C, Steinberg MH
published in: American journal of hematology
information resource reference: HbSC disease: A time for progress. Am J Hematol. 2022 11; 97(11):1390-1393.
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publication date: 2022-09-08T00:00:00
year: 2022
type: Academic Article
type: Article
type: Document
type: Information Resource

Variation and impact of polygenic hematologic traits in monogenic sickle cell disease.
PubMed Identifier: 36226494
author list: Pincez T, Lo KS, D'Orengiani APHD, Garrett ME, Brugnara C, Ashley-Koch AE, Telen MJ, Galacteros F, Joly P, Bartolucci P, Lettre G
published in: Haematologica
information resource reference: Variation and impact of polygenic hematologic traits in monogenic sickle cell disease. Haematologica. 2023 03 01; 108(3):870-881.
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publication date: 2023-03-01T00:00:00
year: 2023
type: Academic Article
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type: Document
type: Information Resource

Authorship 442295
type: Authorship
author rank in publication: 3
linked author: Brugnara, Carlo
linked information resource: Cellular effects of hydroxyurea in Hb SC disease.

Authorship 449021
type: Authorship
author rank in publication: 2
linked author: Brugnara, Carlo
linked information resource: An algorithm using reticulocyte hemoglobin content (CHr) measurement in screening adolescents for iron deficiency.

Authorship 46236
type: Authorship
author rank in publication: 3
linked author: Brugnara, Carlo
linked information resource: Reinterpretation of the RACTK1 K+ channel.

Authorship 465746
type: Authorship
author rank in publication: 1
linked author: Brugnara, Carlo
linked information resource: Furosemide-sensitive Na and K fluxes in human red cells. Net uphill Na extrusion and equilibrium properties.

Authorship 207408
type: Authorship
author rank in publication: 3
linked author: Brugnara, Carlo
linked information resource: Regulation of K-Cl cotransport during reticulocyte maturation and erythrocyte aging in normal and sickle erythrocytes.

Authorship 1516318
type: Authorship
author rank in publication: 1
linked author: Brugnara, Carlo
linked information resource: Immune Therapies in the Treatment of Multiple Myeloma.

Immune Therapies in the Treatment of Multiple Myeloma.
PubMed Identifier: 36660795
author list: Brugnara C
published in: American journal of hematology
information resource reference: Immune Therapies in the Treatment of Multiple Myeloma. Am J Hematol. 2023 Jan 19.
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type: Document
type: Information Resource

Authorship 1518486
type: Authorship
author rank in publication: 1
linked author: Brugnara, Carlo
linked information resource: Immune therapies in the treatment of multiple myeloma.

Immune therapies in the treatment of multiple myeloma.
PubMed Identifier: 36694279
author list: Brugnara C
published in: American journal of hematology
information resource reference: Immune therapies in the treatment of multiple myeloma. Am J Hematol. 2023 03; 98 Suppl 2:S3.
journal title abbreviation: Am J Hematol
publication date: 2023-03-01T00:00:00
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type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1524169
type: Authorship
author rank in publication: 13
linked author: Brugnara, Carlo
linked information resource: Mitapivat, a pyruvate kinase activator, improves transfusion burden and reduces iron overload in ß-thalassemic mice.

Mitapivat, a pyruvate kinase activator, improves transfusion burden and reduces iron overload in ß-thalassemic mice.
PubMed Identifier: 36794508
author list: Mattè A, Kosinski PA, Federti E, Dang L, Recchiuti A, Russo R, Siciliano A, Riccardi V, Janin A, Mucci M, Leboeuf C, Iolascon A, Brugnara C, De Franceschi L
published in: Haematologica
information resource reference: Mitapivat, a pyruvate kinase activator, improves transfusion burden and reduces iron overload in ß-thalassemic mice. Haematologica. 2023 09 01; 108(9):2535-2541.
journal title abbreviation: Haematologica
publication date: 2023-09-01T00:00:00
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type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1531714
type: Authorship
author rank in publication: 20
linked author: Brugnara, Carlo
linked information resource: In Humanized Sickle Cell Mice, Imatinib Protects Against Sickle Cell-Related Injury.

In Humanized Sickle Cell Mice, Imatinib Protects Against Sickle Cell-Related Injury.
PubMed Identifier: 36874380
author list: Federti E, Matte A, Recchiuti A, Garello F, Ghigo A, El Nemer W, Terreno E, Amoresano A, Mattoscio D, Turrini F, Lebouef C, Janin A, Pantaleo A, Russo R, Marin M, Iatcencko I, Riccardi V, Siciliano A, Iolascon A, Brugnara C, De Franceschi L
published in: HemaSphere
information resource reference: In Humanized Sickle Cell Mice, Imatinib Protects Against Sickle Cell-Related Injury. Hemasphere. 2023 Mar; 7(3):e848.
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publication date: 2023-02-28T00:00:00
year: 2023
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type: Article
type: Document
type: Information Resource

Authorship 482603
type: Authorship
author rank in publication: 1
linked author: Brugnara, Carlo
linked information resource: Cell volume, K transport, and cell density in human erythrocytes.

Authorship 1591913
type: Authorship
author rank in publication: 17
linked author: Brugnara, Carlo
linked information resource: Mitapivat reprograms the RBC metabolome and improves anemia in a mouse model of hereditary spherocytosis.

Mitapivat reprograms the RBC metabolome and improves anemia in a mouse model of hereditary spherocytosis.
PubMed Identifier: 37676741
author list: Matte A, Wilson AB, Gevi F, Federti E, Recchiuti A, Ferri G, Brunati AM, Pagano MA, Russo R, Leboeuf C, Janin A, Timperio AM, Iolascon A, Gremese E, Dang L, Mohandas N, Brugnara C, De Franceschi L
published in: JCI insight
information resource reference: Mitapivat reprograms the RBC metabolome and improves anemia in a mouse model of hereditary spherocytosis. JCI Insight. 2023 10 23; 8(20).
journal title abbreviation: JCI Insight
publication date: 2023-10-23T00:00:00
year: 2023
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 42040
type: Authorship
author rank in publication: 4
linked author: Brugnara, Carlo
linked information resource: Pharmacological inhibition of calpain-1 prevents red cell dehydration and reduces Gardos channel activity in a mouse model of sickle cell disease.

Authorship 1614050
type: Authorship
author rank in publication: 15
linked author: Brugnara, Carlo
linked information resource: Epeleuton, a novel synthetic ?-3 fatty acid, reduces hypoxia/ reperfusion stress in a mouse model of sickle cell disease.

Epeleuton, a novel synthetic ?-3 fatty acid, reduces hypoxia/ reperfusion stress in a mouse model of sickle cell disease.
PubMed Identifier: 38105727
author list: Mattè A, Federti E, Recchiuti A, Hamza M, Ferri G, Riccardi V, Ceolan J, Passarini A, Mazzi F, Siciliano A, Bhatt DL, Coughlan D, Climax J, Gremese E, Brugnara C, De Franceschi L
published in: Haematologica
information resource reference: Epeleuton, a novel synthetic ?-3 fatty acid, reduces hypoxia/ reperfusion stress in a mouse model of sickle cell disease. Haematologica. 2024 06 01; 109(6):1918-1932.
journal title abbreviation: Haematologica
publication date: 2024-06-01T00:00:00
year: 2024
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 516584
type: Authorship
author rank in publication: 8
linked author: Brugnara, Carlo
linked information resource: Flow-cytometric analysis of erythrocytes and reticulocytes in congenital dyserythropoietic anaemia type II (CDA II): value in differential diagnosis with hereditary spherocytosis.

Authorship 553221
type: Authorship
author rank in publication: 2
linked author: Brugnara, Carlo
linked information resource: The effects of hydroxycarbamide and magnesium on haemoglobin SC disease: results of the multi-centre CHAMPS trial.

Authorship 571884
type: Authorship
author rank in publication: 3
linked author: Brugnara, Carlo
linked information resource: The antifungal imidazole clotrimazole and its major in vivo metabolite are potent blockers of the calcium-activated potassium channel in murine erythroleukemia cells.

Authorship 161871
type: Authorship
author rank in publication: 4
linked author: Brugnara, Carlo
linked information resource: The antifungal antibiotic, clotrimazole, inhibits Cl- secretion by polarized monolayers of human colonic epithelial cells.

Acute Promyelocytic Leukemia With Torque Teno Mini Virus::RARA Fusion: An Approach to Screening and Diagnosis.
PubMed Identifier: 38704030
author list: Tsai HK, Sabbagh MF, Montesion M, Williams EA, Arbini A, Boué DR, Harris EM, Wachter F, Grimmett L, Place AE, Lucas F, Nardi V, Kim AS, Brugnara C, Degar B, Pollard J, Harris MH, Bledsoe JR
published in: Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc
information resource reference: Acute Promyelocytic Leukemia With Torque Teno Mini Virus::RARA Fusion: An Approach to Screening and Diagnosis. Mod Pathol. 2024 Jul; 37(7):100509.
journal title abbreviation: Mod Pathol
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type: Article
type: Document
type: Information Resource

Authorship 255059
type: Authorship
author rank in publication: 3
linked author: Brugnara, Carlo
linked information resource: Plasminogen activator inhibitor-1: defining characteristics in the cerebrospinal fluid of newborns.

Authorship 1651727
type: Authorship
author rank in publication: 18
linked author: Brugnara, Carlo
linked information resource: Nrf2 Plays a Key Role in Erythropoiesis during Aging.

Authorship 1649165
type: Authorship
author rank in publication: 14
linked author: Brugnara, Carlo
linked information resource: Acute Promyelocytic Leukemia With Torque Teno Mini Virus::RARA Fusion: An Approach to Screening and Diagnosis.

Nrf2 Plays a Key Role in Erythropoiesis during Aging.
PubMed Identifier: 38671902
author list: Mbiandjeu SCT, Siciliano A, Mattè A, Federti E, Perduca M, Melisi D, Andolfo I, Amoresano A, Iolascon A, Valenti MT, Turrini F, Bovi M, Pisani A, Recchiuti A, Mattoscio D, Riccardi V, Dalle Carbonare L, Brugnara C, Mohandas N, De Franceschi L
published in: Antioxidants (Basel, Switzerland)
information resource reference: Nrf2 Plays a Key Role in Erythropoiesis during Aging. Antioxidants (Basel). 2024 Apr 12; 13(4).
journal title abbreviation: Antioxidants (Basel)
publication date: 2024-04-12T00:00:00
year: 2024
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 239313
type: Authorship
author rank in publication: 2
linked author: Brugnara, Carlo
linked information resource: Properties of the Na+-K+ pump in human red cells with increased number of pump sites.

Authorship 24251
type: Authorship
author rank in publication: 1
linked author: Brugnara, Carlo
linked information resource: Therapy with oral clotrimazole induces inhibition of the Gardos channel and reduction of erythrocyte dehydration in patients with sickle cell disease.

Authorship 1669332
type: Authorship
author rank in publication: 2
linked author: Brugnara, Carlo
linked information resource: Hematology Laboratory in the Digital and Automation Age.

Hematology Laboratory in the Digital and Automation Age.
PubMed Identifier: 39089759
author list: Pozdnyakova O, Brugnara C
published in: Clinics in laboratory medicine
information resource reference: Hematology Laboratory in the Digital and Automation Age. Clin Lab Med. 2024 Sep; 44(3):xiii-xiv.
journal title abbreviation: Clin Lab Med
publication date: 2024-06-18T00:00:00
year: 2024
type: Academic Article
type: Article
type: Document
type: Information Resource

Assistant Professor of Medicine
is primary position: true
position in department: Medicine
position in division: Nephrology
sort order: 1
type: Position
HR job title: Assistant Professor of Medicine
position in organization: Beth Israel Deaconess Medical Center

Authorship 436323
type: Authorship
author rank in publication: 1
linked author: Brugnara, Carlo
linked information resource: Reticulocyte hemoglobin equivalent (Ret He) and assessment of iron-deficient states.

Authorship 1679073
type: Authorship
author rank in publication: 2
linked author: Brugnara, Carlo
linked information resource: Self-pay laboratory charges for iron deficiency diagnosis in the Boston and New Haven metropolitan areas.

Self-pay laboratory charges for iron deficiency diagnosis in the Boston and New Haven metropolitan areas.
PubMed Identifier: 39119854
author list: Van Doren L, Brugnara C
published in: American journal of hematology
information resource reference: Self-pay laboratory charges for iron deficiency diagnosis in the Boston and New Haven metropolitan areas. Am J Hematol. 2024 Nov; 99(11):2233-2235.
journal title abbreviation: Am J Hematol
publication date: 2024-08-09T00:00:00
year: 2024
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 486439
type: Authorship
author rank in publication: 10
linked author: Brugnara, Carlo
linked information resource: Protective effects of S-nitrosoalbumin on lung injury induced by hypoxia-reoxygenation in mouse model of sickle cell disease.

Authorship 658131
type: Authorship
author rank in publication: 1
linked author: Brugnara, Carlo
linked information resource: Iron deficiency: what are the future trends in diagnostics and therapeutics?

Authorship 666705
type: Authorship
author rank in publication: 19
linked author: Brugnara, Carlo
linked information resource: Multiple clinical forms of dehydrated hereditary stomatocytosis arise from mutations in PIEZO1.

Authorship 666707
type: Authorship
author rank in publication: 5
linked author: Brugnara, Carlo
linked information resource: Strain-specific variations in cation content and transport in mouse erythrocytes.

Iron deficiency: what are the future trends in diagnostics and therapeutics?
PubMed Identifier: 23150055
author list: Brugnara C, Adamson J, Auerbach M, Kane R, Macdougall I, Mast A
published in: Clinical chemistry
information resource reference: Iron deficiency: what are the future trends in diagnostics and therapeutics? Clin Chem. 2013 May; 59(5):740-5.
journal title abbreviation: Clin Chem
publication date: 2012-11-13T00:00:00
year: 2012
type: Academic Article
type: Article
type: Document
type: Information Resource

Multiple clinical forms of dehydrated hereditary stomatocytosis arise from mutations in PIEZO1.
PubMed Identifier: 23479567
author list: Andolfo I, Alper SL, De Franceschi L, Auriemma C, Russo R, De Falco L, Vallefuoco F, Esposito MR, Vandorpe DH, Shmukler BE, Narayan R, Montanaro D, D'Armiento M, Vetro A, Limongelli I, Zuffardi O, Glader BE, Schrier SL, Brugnara C, Stewart GW, Delaunay J, Iolascon A
published in: Blood
information resource reference: Multiple clinical forms of dehydrated hereditary stomatocytosis arise from mutations in PIEZO1. Blood. 2013 May 09; 121(19):3925-35, S1-12.
journal title abbreviation: Blood
publication date: 2013-03-11T00:00:00
year: 2013
type: Academic Article
type: Article
type: Document
type: Information Resource

Strain-specific variations in cation content and transport in mouse erythrocytes.
PubMed Identifier: 23482811
author list: Rivera A, Zee RY, Alper SL, Peters LL, Brugnara C
published in: Physiological genomics
information resource reference: Strain-specific variations in cation content and transport in mouse erythrocytes. Physiol Genomics. 2013 May 01; 45(9):343-50.
journal title abbreviation: Physiol Genomics
publication date: 2013-03-12T00:00:00
year: 2013
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1694055
type: Authorship
author rank in publication: 4
linked author: Brugnara, Carlo
linked information resource: Biomechanics of phagocytosis of red blood cells by macrophages in the human spleen.

Biomechanics of phagocytosis of red blood cells by macrophages in the human spleen.
PubMed Identifier: 39453740
author list: Li H, Qiang Y, Li X, Brugnara C, Buffet PA, Dao M, Karniadakis GE, Suresh S
published in: Proceedings of the National Academy of Sciences of the United States of America
information resource reference: Biomechanics of phagocytosis of red blood cells by macrophages in the human spleen. Proc Natl Acad Sci U S A. 2024 Oct 29; 121(44):e2414437121.
journal title abbreviation: Proc Natl Acad Sci U S A
publication date: 2024-10-25T00:00:00
year: 2024
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 78998
type: Authorship
author rank in publication: 5
linked author: Brugnara, Carlo
linked information resource: Foxo3 is required for the regulation of oxidative stress in erythropoiesis.

Authorship 68024
type: Authorship
author rank in publication: 1
linked author: Brugnara, Carlo
linked information resource: Regulation of erythrocyte cation and water content in sickle cell anemia.

Authorship 82245
type: Authorship
author rank in publication: 2
linked author: Brugnara, Carlo
linked information resource: Pathophysiological-based approaches to treatment of sickle cell disease.

Authorship 553509
type: Authorship
author rank in publication: 4
linked author: Brugnara, Carlo
linked information resource: Quantitative trait loci for baseline white blood cell count, platelet count, and mean platelet volume.

Authorship 218291
type: Authorship
author rank in publication: 3
linked author: Brugnara, Carlo
linked information resource: Protein phosphatase 1alpha is tyrosine-phosphorylated and inactivated by peroxynitrite in erythrocytes through the src family kinase fgr.

Authorship 224129
type: Authorship
author rank in publication: 1
linked author: Brugnara, Carlo
linked information resource: Erythrocyte membrane transport physiology.

Authorship 246708
type: Authorship
author rank in publication: 6
linked author: Brugnara, Carlo
linked information resource: Preliminary assessment of inhaled nitric oxide for acute vaso-occlusive crisis in pediatric patients with sickle cell disease.

Authorship 279681
type: Authorship
author rank in publication: 4
linked author: Brugnara, Carlo
linked information resource: Elevation of red cell sodium-lithium countertransport in hyperlipidemias.

Authorship 305012
type: Authorship
author rank in publication: 5
linked author: Brugnara, Carlo
linked information resource: Hemolytic anemia induced by ribavirin therapy in patients with chronic hepatitis C virus infection: role of membrane oxidative damage.

Authorship 309080
type: Authorship
author rank in publication: 2
linked author: Brugnara, Carlo
linked information resource: Modes of operation and variable stoichiometry of the furosemide- sensitive Na and K fluxes in human red cells.

Authorship 1728868
type: Authorship
author rank in publication: 15
linked author: Brugnara, Carlo
linked information resource: 17(R)-Resolvin D1 protects against sickle cell-related inflammatory cardiomyopathy in humanized mice.

17(R)-Resolvin D1 protects against sickle cell-related inflammatory cardiomyopathy in humanized mice.
PubMed Identifier: 39928855
author list: Federti E, Mattoscio D, Recchiuti A, Matte A, Monti M, Cozzolino F, Iezzi M, Ceci M, Ghigo A, Tolosano E, Siciliano A, Ceolan J, Riccardi V, Gremese E, Brugnara C, De Franceschi L
published in: Blood
information resource reference: 17(R)-Resolvin D1 protects against sickle cell-related inflammatory cardiomyopathy in humanized mice. Blood. 2025 Apr 24; 145(17):1915-1928.
journal title abbreviation: Blood
publication date: 2025-04-24T00:00:00
year: 2025
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 352385
type: Authorship
author rank in publication: 6
linked author: Brugnara, Carlo
linked information resource: Screening healthy infants for iron deficiency using reticulocyte hemoglobin content.

Professor of Pediatrics, Emerita
is primary position: true
position in department: Emeritus
position in division: https://connects.catalyst.harvard.edu/Profiles/profile/1229413
sort order: 1
type: Position
HR job title: Professor of Pediatrics, Emerita
position in organization: Harvard Medical School

Authorship 1749905
type: Authorship
author rank in publication: 17
linked author: Brugnara, Carlo
linked information resource: Mitapivat metabolically reprograms human ß-thalassemic erythroblasts, increasing their responsiveness to oxidation.

Authorship 1749998
type: Authorship
author rank in publication: 1
linked author: Brugnara, Carlo
linked information resource: Contemporary Topics in Myeloproliferative Neoplasms and Myelodysplastic Syndromes: American Journal of Hematology 100th Volume Anniversary Symposium.

Mitapivat metabolically reprograms human ß-thalassemic erythroblasts, increasing their responsiveness to oxidation.
PubMed Identifier: 40085946
author list: Siciliano A, D'Alessandro A, Matte A, Bisello G, Bertoldi M, Dzieciatkowska M, Argabright A, Pozzetto RH, Riccardi V, Mattarei A, Ongaro A, Ceolan J, Russo R, Rivadeneyra L, Wind-Rotolo M, Iolascon A, Brugnara C, De Franceschi L
published in: Blood advances
information resource reference: Mitapivat metabolically reprograms human ß-thalassemic erythroblasts, increasing their responsiveness to oxidation. Blood Adv. 2025 Jun 10; 9(11):2818-2830.
journal title abbreviation: Blood Adv
publication date: 2025-06-10T00:00:00
year: 2025
type: Academic Article
type: Article
type: Document
type: Information Resource

Contemporary Topics in Myeloproliferative Neoplasms and Myelodysplastic Syndromes: American Journal of Hematology 100th Volume Anniversary Symposium.
PubMed Identifier: 40087835
author list: Brugnara C, Vannucchi AM, Tefferi A
published in: American journal of hematology
information resource reference: Contemporary Topics in Myeloproliferative Neoplasms and Myelodysplastic Syndromes: American Journal of Hematology 100th Volume Anniversary Symposium. Am J Hematol. 2025 Jun; 100 Suppl 4:3-4.
journal title abbreviation: Am J Hematol
publication date: 2025-03-14T00:00:00
year: 2025
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 695926
type: Authorship
author rank in publication: 5
linked author: Brugnara, Carlo
linked information resource: Dehydrated stomatocytic anemia due to the heterozygous mutation R2456H in the mechanosensitive cation channel PIEZO1: a case report.

Dehydrated stomatocytic anemia due to the heterozygous mutation R2456H in the mechanosensitive cation channel PIEZO1: a case report.
PubMed Identifier: 23973043
author list: Shmukler BE, Vandorpe DH, Rivera A, Auerbach M, Brugnara C, Alper SL
published in: Blood cells, molecules & diseases
information resource reference: Dehydrated stomatocytic anemia due to the heterozygous mutation R2456H in the mechanosensitive cation channel PIEZO1: a case report. Blood Cells Mol Dis. 2014 Jan; 52(1):53-4.
journal title abbreviation: Blood Cells Mol Dis
publication date: 2013-08-23T00:00:00
year: 2013
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 27214
type: Authorship
author rank in publication: 7
linked author: Brugnara, Carlo
linked information resource: HPLC measurement, blood distribution, and pharmacokinetics of oral clotrimazole, potentially useful antisickling agent.

Authorship 274965
type: Authorship
author rank in publication: 1
linked author: Brugnara, Carlo
linked information resource: Acid pH induces formation of dense cells in sickle erythrocytes.

Authorship 278663
type: Authorship
author rank in publication: 1
linked author: Brugnara, Carlo
linked information resource: Reticulocyte hemoglobin content to diagnose iron deficiency in children.

Authorship 316040
type: Authorship
author rank in publication: 5
linked author: Brugnara, Carlo
linked information resource: Use of a preoperative bleeding questionnaire in pediatric patients who undergo adenotonsillectomy.

Authorship 284635
type: Authorship
author rank in publication: 1
linked author: Brugnara, Carlo
linked information resource: Iron deficiency and erythropoiesis: new diagnostic approaches.

Authorship 300474
type: Authorship
author rank in publication: 11
linked author: Brugnara, Carlo
linked information resource: Sequence variation at multiple loci influences red cell hemoglobin concentration.

Authorship 720337
type: Authorship
author rank in publication: 4
linked author: Brugnara, Carlo
linked information resource: Resveratrol accelerates erythroid maturation by activation of FoxO3 and ameliorates anemia in beta-thalassemic mice.

Authorship 723208
type: Authorship
author rank in publication: 4
linked author: Brugnara, Carlo
linked information resource: Alpha-thalassaemia and response to hydroxyurea in sickle cell anaemia.

Resveratrol accelerates erythroid maturation by activation of FoxO3 and ameliorates anemia in beta-thalassemic mice.
PubMed Identifier: 23975182
author list: Franco SS, De Falco L, Ghaffari S, Brugnara C, Sinclair DA, Matte' A, Iolascon A, Mohandas N, Bertoldi M, An X, Siciliano A, Rimmelé P, Cappellini MD, Michan S, Zoratti E, Anne J, De Franceschi L
published in: Haematologica
information resource reference: Resveratrol accelerates erythroid maturation by activation of FoxO3 and ameliorates anemia in beta-thalassemic mice. Haematologica. 2014 Feb; 99(2):267-75.
journal title abbreviation: Haematologica
publication date: 2013-08-23T00:00:00
year: 2013
type: Academic Article
type: Article
type: Document
type: Information Resource

Alpha-thalassaemia and response to hydroxyurea in sickle cell anaemia.
PubMed Identifier: 24330217
author list: Darbari DS, Nouraie M, Taylor JG, Brugnara C, Castro O, Ballas SK
published in: European journal of haematology
information resource reference: Alpha-thalassaemia and response to hydroxyurea in sickle cell anaemia. Eur J Haematol. 2014 Apr; 92(4):341-5.
journal title abbreviation: Eur J Haematol
publication date: 2014-01-30T00:00:00
year: 2014
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 208127
type: Authorship
author rank in publication: 2
linked author: Brugnara, Carlo
linked information resource: Prevention of red cell dehydration: a possible new treatment for sickle cell disease.

Authorship 333690
type: Authorship
author rank in publication: 5
linked author: Brugnara, Carlo
linked information resource: A novel method utilising markers of altered erythropoiesis for the detection of recombinant human erythropoietin abuse in athletes.

Authorship 245592
type: Authorship
author rank in publication: 4
linked author: Brugnara, Carlo
linked information resource: Degree of agreement in plasma fibrinogen among two functional and one immunonephelometric assays.

Authorship 1816104
type: Authorship
author rank in publication: 18
linked author: Brugnara, Carlo
linked information resource: A xeno-free red blood cell differentiation formula models sickle cell disease from somatically sourced patient iPSCs.

A xeno-free red blood cell differentiation formula models sickle cell disease from somatically sourced patient iPSCs.
PubMed Identifier: 40957551
author list: Conway AJ, Rosanwo TO, Williamson TE, Landry S, Kinney MA, Clark MA, Vo LT, Rowe RG, Marion W, Zhang Y, Mullin NK, Shi M, Archer NM, Heeney MM, Schlaeger TM, Bauer DE, Duraisingh MT, Brugnara C, North TE, Daley GQ
published in: Experimental hematology
information resource reference: A xeno-free red blood cell differentiation formula models sickle cell disease from somatically sourced patient iPSCs. Exp Hematol. 2025 Dec; 152:105264.
journal title abbreviation: Exp Hematol
publication date: 2025-09-14T00:00:00
year: 2025
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 296911
type: Authorship
author rank in publication: 1
linked author: Brugnara, Carlo
linked information resource: A new therapeutic approach for sickle cell disease. Blockade of the red cell Ca(2+)-activated K+ channel by clotrimazole.

Authorship 207416
type: Authorship
author rank in publication: 4
linked author: Brugnara, Carlo
linked information resource: Maximum urine concentrating ability in children with Hb SC disease: effects of hydroxyurea.

Professor of Medicine
is primary position: true
position in department: Medicine
position in division: Nephrology
sort order: 1
type: Position
HR job title: Professor of Medicine
position in organization: Beth Israel Deaconess Medical Center

Authorship 409744
type: Authorship
author rank in publication: 1
linked author: Brugnara, Carlo
linked information resource: Lithium-sodium countertransport in erythrocytes of normal and hypertensive subjects. Relationship with age and plasma renin activity.

Authorship 422271
type: Authorship
author rank in publication: 1
linked author: Brugnara, Carlo
linked information resource: Ca(2+)-activated K+ channels of human and rabbit erythrocytes display distinctive patterns of inhibition by venom peptide toxins.

Professor of Pathology
is primary position: true
position in department: Pathology
position in division: https://connects.catalyst.harvard.edu/Profiles/profile/1229413
sort order: 1
type: Position
HR job title: Professor of Pathology
position in organization: Brigham and Women's Hospital

Authorship 322693
type: Authorship
author rank in publication: 2
linked author: Brugnara, Carlo
linked information resource: Treatment of sickle cell anemia with hydroxyurea and erythropoietin.

John LaPorte Given Professor of Immunology and Infectious Diseases
is primary position: true
position in department: Malaria/Wirth
position in division: https://connects.catalyst.harvard.edu/Profiles/profile/1229413
sort order: 1
type: Position
HR job title: John LaPorte Given Professor of Immunology and Infectious Diseases
position in organization: Harvard T.H. Chan School of Public Health

Assistant Professor of Pathology
is primary position: true
position in department: Pathology
position in division: https://connects.catalyst.harvard.edu/Profiles/profile/1229413
sort order: 1
type: Position
HR job title: Assistant Professor of Pathology
position in organization: Boston Children's Hospital

S. Burt Wolbach Professor of Pathology
is primary position: true
position in department: Pathology
position in division: https://connects.catalyst.harvard.edu/Profiles/profile/1229413
sort order: 1
type: Position
HR job title: S. Burt Wolbach Professor of Pathology
position in organization: Boston Children's Hospital

Associate Professor of Pathology
is primary position: true
position in department: Pathology
position in division: https://connects.catalyst.harvard.edu/Profiles/profile/1229413
sort order: 1
type: Position
HR job title: Associate Professor of Pathology
position in organization: Boston Children's Hospital

Associate Professor of Pediatrics
is primary position: true
position in department: Pediatrics
position in division: Hematology/Oncology
sort order: 1
type: Position
HR job title: Associate Professor of Pediatrics
position in organization: Boston Children's Hospital

Professor of Pathology
is primary position: true
position in department: Pathology
position in division: https://connects.catalyst.harvard.edu/Profiles/profile/1229413
sort order: 1
type: Position
HR job title: Professor of Pathology
position in organization: Boston Children's Hospital

Associate Professor of Pathology
is primary position: true
position in department: Pathology
position in division: https://connects.catalyst.harvard.edu/Profiles/profile/1229413
sort order: 1
type: Position
HR job title: Associate Professor of Pathology
position in organization: Boston Children's Hospital

Visiting Scientist
is primary position: true
position in department: Immunology and Infectious Diseases
position in division: https://connects.catalyst.harvard.edu/Profiles/profile/1229413
sort order: 1
type: Position
HR job title: Visiting Scientist
position in organization: Harvard T.H. Chan School of Public Health

Professor of Pathology
is primary position: true
position in department: Pathology
position in division: https://connects.catalyst.harvard.edu/Profiles/profile/1229413
sort order: 1
type: Position
HR job title: Professor of Pathology
position in organization: Boston Children's Hospital

Professor of Pathology
is primary position: true
position in department: Pathology
position in division: https://connects.catalyst.harvard.edu/Profiles/profile/1229413
sort order: 1
type: Position
HR job title: Professor of Pathology
position in organization: Boston Children's Hospital

Authorship 30023
type: Authorship
author rank in publication: 11
linked author: Brugnara, Carlo
linked information resource: Mild spherocytosis and altered red cell ion transport in protein 4. 2-null mice.

Authorship 475003
type: Authorship
author rank in publication: 1
linked author: Brugnara, Carlo
linked information resource: Inhibition of Ca(2+)-dependent K+ transport and cell dehydration in sickle erythrocytes by clotrimazole and other imidazole derivatives.

Authorship 476481
type: Authorship
author rank in publication: 1
linked author: Brugnara, Carlo
linked information resource: Erythrocyte-active agents and treatment of sickle cell disease.

Authorship 49557
type: Authorship
author rank in publication: 1
linked author: Brugnara, Carlo
linked information resource: Ca(2+)-activated K+ transport in erythrocytes. Comparison of binding and transport inhibition by scorpion toxins.

Authorship 750312
type: Authorship
author rank in publication: 8
linked author: Brugnara, Carlo
linked information resource: Aging-like phenotype and defective lineage specification in SIRT1-deleted hematopoietic stem and progenitor cells.

Aging-like phenotype and defective lineage specification in SIRT1-deleted hematopoietic stem and progenitor cells.
PubMed Identifier: 25068121
author list: Rimmelé P, Bigarella CL, Liang R, Izac B, Dieguez-Gonzalez R, Barbet G, Donovan M, Brugnara C, Blander JM, Sinclair DA, Ghaffari S
published in: Stem cell reports
information resource reference: Aging-like phenotype and defective lineage specification in SIRT1-deleted hematopoietic stem and progenitor cells. Stem Cell Reports. 2014 Jul 08; 3(1):44-59.
journal title abbreviation: Stem Cell Reports
publication date: 2014-06-06T00:00:00
year: 2014
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 754686
type: Authorship
author rank in publication: 3
linked author: Brugnara, Carlo
linked information resource: Optical assay of erythrocyte function in banked blood.

Optical assay of erythrocyte function in banked blood.
PubMed Identifier: 25189281
author list: Bhaduri B, Kandel M, Brugnara C, Tangella K, Popescu G
published in: Scientific reports
information resource reference: Optical assay of erythrocyte function in banked blood. Sci Rep. 2014 Sep 05; 4:6211.
journal title abbreviation: Sci Rep
publication date: 2014-09-05T00:00:00
year: 2014
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 758127
type: Authorship
author rank in publication: 10
linked author: Brugnara, Carlo
linked information resource: FOXO3-mTOR metabolic cooperation in the regulation of erythroid cell maturation and homeostasis.

FOXO3-mTOR metabolic cooperation in the regulation of erythroid cell maturation and homeostasis.
PubMed Identifier: 24966026
author list: Zhang X, Campreciós G, Rimmelé P, Liang R, Yalcin S, Mungamuri SK, Barminko J, D'Escamard V, Baron MH, Brugnara C, Papatsenko D, Rivella S, Ghaffari S
published in: American journal of hematology
information resource reference: FOXO3-mTOR metabolic cooperation in the regulation of erythroid cell maturation and homeostasis. Am J Hematol. 2014 Oct; 89(10):954-63.
journal title abbreviation: Am J Hematol
publication date: 2014-07-22T00:00:00
year: 2014
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 386813
type: Authorship
author rank in publication: 2
linked author: Brugnara, Carlo
linked information resource: Hydroxyurea and sickle cell disease: a chance for every patient.

Authorship 764181
type: Authorship
author rank in publication: 9
linked author: Brugnara, Carlo
linked information resource: Density-based separation in multiphase systems provides a simple method to identify sickle cell disease.

Density-based separation in multiphase systems provides a simple method to identify sickle cell disease.
PubMed Identifier: 25197072
author list: Kumar AA, Patton MR, Hennek JW, Lee SY, D'Alesio-Spina G, Yang X, Kanter J, Shevkoplyas SS, Brugnara C, Whitesides GM
published in: Proceedings of the National Academy of Sciences of the United States of America
information resource reference: Density-based separation in multiphase systems provides a simple method to identify sickle cell disease. Proc Natl Acad Sci U S A. 2014 Oct 14; 111(41):14864-9.
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publication date: 2014-09-02T00:00:00
year: 2014
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 460308
type: Authorship
author rank in publication: 8
linked author: Brugnara, Carlo
linked information resource: Deferiprone therapy in homozygous human beta-thalassemia removes erythrocyte membrane free iron and reduces KCl cotransport activity.

Authorship 227716
type: Authorship
author rank in publication: 8
linked author: Brugnara, Carlo
linked information resource: Hypoxia activates a Ca2+-permeable cation conductance sensitive to carbon monoxide and to GsMTx-4 in human and mouse sickle erythrocytes.

Authorship 769948
type: Authorship
author rank in publication: 12
linked author: Brugnara, Carlo
linked information resource: Hereditary xerocytosis revisited.

Hereditary xerocytosis revisited.
PubMed Identifier: 25044010
author list: Archer NM, Shmukler BE, Andolfo I, Vandorpe DH, Gnanasambandam R, Higgins JM, Rivera A, Fleming MD, Sachs F, Gottlieb PA, Iolascon A, Brugnara C, Alper SL, Nathan DG
published in: American journal of hematology
information resource reference: Hereditary xerocytosis revisited. Am J Hematol. 2014 Dec; 89(12):1142-6.
journal title abbreviation: Am J Hematol
publication date: 2014-07-21T00:00:00
year: 2014
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 366893
type: Authorship
author rank in publication: 4
linked author: Brugnara, Carlo
linked information resource: Early detection of response to hydroxyurea therapy in patients with sickle cell anemia.

Authorship 370240
type: Authorship
author rank in publication: 5
linked author: Brugnara, Carlo
linked information resource: The effect of intravenous iron on the reticulocyte response to recombinant human erythropoietin.

Authorship 775745
type: Authorship
author rank in publication: 11
linked author: Brugnara, Carlo
linked information resource: Evaluation of a density-based rapid diagnostic test for sickle cell disease in a clinical setting in Zambia.

Evaluation of a density-based rapid diagnostic test for sickle cell disease in a clinical setting in Zambia.
PubMed Identifier: 25490722
author list: Kumar AA, Chunda-Liyoka C, Hennek JW, Mantina H, Lee SY, Patton MR, Sambo P, Sinyangwe S, Kankasa C, Chintu C, Brugnara C, Stossel TP, Whitesides GM
published in: PloS one
information resource reference: Evaluation of a density-based rapid diagnostic test for sickle cell disease in a clinical setting in Zambia. PLoS One. 2014; 9(12):e114540.
journal title abbreviation: PLoS One
publication date: 2014-12-09T00:00:00
year: 2014
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 492422
type: Authorship
author rank in publication: 4
linked author: Brugnara, Carlo
linked information resource: K-Cl cotransport modulation by intracellular Mg in erythrocytes from mice bred for low and high Mg levels.

Authorship 510886
type: Authorship
author rank in publication: 1
linked author: Brugnara, Carlo
linked information resource: Reticulocyte cellular indices: a new approach in the diagnosis of anemias and monitoring of erythropoietic function.

Authorship 494064
type: Authorship
author rank in publication: 1
linked author: Brugnara, Carlo
linked information resource: Effects of subcutaneous recombinant human erythropoietin in normal subjects: development of decreased reticulocyte hemoglobin content and iron-deficient erythropoiesis.

Authorship 777590
type: Authorship
author rank in publication: 1
linked author: Brugnara, Carlo
linked information resource: American Journal of Hematology, getting ready for the 40th birthday in 2016.

Authorship 778120
type: Authorship
author rank in publication: 2
linked author: Brugnara, Carlo
linked information resource: Reductions in red blood cell 2,3-diphosphoglycerate concentration during continuous renal replacment therapy.

American Journal of Hematology, getting ready for the 40th birthday in 2016.
PubMed Identifier: 25418109
author list: Brugnara C
published in: American journal of hematology
information resource reference: American Journal of Hematology, getting ready for the 40th birthday in 2016. Am J Hematol. 2015 Jan; 90(1):1.
journal title abbreviation: Am J Hematol
publication date: 2015-01-01T00:00:00
year: 2015
type: Academic Article
type: Article
type: Document
type: Information Resource

Reductions in red blood cell 2,3-diphosphoglycerate concentration during continuous renal replacment therapy.
PubMed Identifier: 25538269
author list: Sharma S, Brugnara C, Betensky RA, Waikar SS
published in: Clinical journal of the American Society of Nephrology : CJASN
information resource reference: Reductions in red blood cell 2,3-diphosphoglycerate concentration during continuous renal replacment therapy. Clin J Am Soc Nephrol. 2015 Jan 07; 10(1):74-9.
journal title abbreviation: Clin J Am Soc Nephrol
publication date: 2014-12-23T00:00:00
year: 2014
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 566986
type: Authorship
author rank in publication: 7
linked author: Brugnara, Carlo
linked information resource: Anion exchanger 1 (band 3) is required to prevent erythrocyte membrane surface loss but not to form the membrane skeleton.

Authorship 576658
type: Authorship
author rank in publication: 5
linked author: Brugnara, Carlo
linked information resource: 5-hydroxymethyl-2-furfural modifies intracellular sickle haemoglobin and inhibits sickling of red blood cells.

Authorship 287540
type: Authorship
author rank in publication: 5
linked author: Brugnara, Carlo
linked information resource: Physiological roles of the intermediate conductance, Ca2+-activated potassium channel Kcnn4.

Authorship 29238
type: Authorship
author rank in publication: 6
linked author: Brugnara, Carlo
linked information resource: Mouse K-Cl cotransporter KCC1: cloning, mapping, pathological expression, and functional regulation.

Authorship 527420
type: Authorship
author rank in publication: 2
linked author: Brugnara, Carlo
linked information resource: Bradykinin and vasopressin stimulate Na+-K+-Cl- cotransport in cultured endothelial cells.

Authorship 95613
type: Authorship
author rank in publication: 4
linked author: Brugnara, Carlo
linked information resource: Full disclosure in industry-sponsored laboratory medicine research studies: statement by the Consortium of Laboratory Medicine Journal Editors.

Authorship 390432
type: Authorship
author rank in publication: 4
linked author: Brugnara, Carlo
linked information resource: A high-performance liquid chromatographic assay for the determination of itraconazole concentration using solid-phase extraction and small sample volume.

Authorship 394027
type: Authorship
author rank in publication: 4
linked author: Brugnara, Carlo
linked information resource: Full-disclosure in industry-sponsored laboratory medicine research studies: statement by the Consortium of Laboratory Medicine Journal Editors.

Authorship 380592
type: Authorship
author rank in publication: 2
linked author: Brugnara, Carlo
linked information resource: Hydroxyurea and erythropoietin therapy in sickle cell anemia.

Authorship 427779
type: Authorship
author rank in publication: 3
linked author: Brugnara, Carlo
linked information resource: Anemia in hemodialysis patients: variables affecting this outcome predictor.

Authorship 44664
type: Authorship
author rank in publication: 2
linked author: Brugnara, Carlo
linked information resource: Low concentrations of nitric oxide increase oxygen affinity of sickle erythrocytes in vitro and in vivo.

Authorship 43029
type: Authorship
author rank in publication: 7
linked author: Brugnara, Carlo
linked information resource: Treatment with NS3623, a novel Cl-conductance blocker, ameliorates erythrocyte dehydration in transgenic SAD mice: a possible new therapeutic approach for sickle cell disease.

Authorship 427339
type: Authorship
author rank in publication: 6
linked author: Brugnara, Carlo
linked information resource: Disruption of erythroid K-Cl cotransporters alters erythrocyte volume and partially rescues erythrocyte dehydration in SAD mice.

Authorship 46998
type: Authorship
author rank in publication: 2
linked author: Brugnara, Carlo
linked information resource: Cation transport in mouse erythrocytes: role of K(+)-Cl- cotransport in regulatory volume decrease.

Authorship 356995
type: Authorship
author rank in publication: 5
linked author: Brugnara, Carlo
linked information resource: Regulation of K-Cl cotransport by protein phosphatase 1alpha in mouse erythrocytes.

Authorship 265887
type: Authorship
author rank in publication: 9
linked author: Brugnara, Carlo
linked information resource: Membrane polyunsaturated fatty acids and lithium-sodium countertransport in human erythrocytes.

Authorship 173368
type: Authorship
author rank in publication: 6
linked author: Brugnara, Carlo
linked information resource: Positional cloning of the zebrafish sauternes gene: a model for congenital sideroblastic anaemia.

Authorship 458359
type: Authorship
author rank in publication: 4
linked author: Brugnara, Carlo
linked information resource: Failure of red blood cell maturation in mice with defects in the high-density lipoprotein receptor SR-BI.

Authorship 21952
type: Authorship
author rank in publication: 2
linked author: Brugnara, Carlo
linked information resource: Clotrimazole inhibits cell proliferation in vitro and in vivo.

Authorship 219866
type: Authorship
author rank in publication: 4
linked author: Brugnara, Carlo
linked information resource: An appeal to medical journal editors: the need for a full description of laboratory methods and specimen handling in clinical study reports.

Authorship 368639
type: Authorship
author rank in publication: 4
linked author: Brugnara, Carlo
linked information resource: Fetal anemia and apoptosis of red cell progenitors in Stat5a-/-5b-/- mice: a direct role for Stat5 in Bcl-X(L) induction.

Authorship 211385
type: Authorship
author rank in publication: 4
linked author: Brugnara, Carlo
linked information resource: Stimulation of human erythrocyte K-Cl cotransport and protein phosphatase type 2A by n-ethylmaleimide: role of intracellular Mg++.

Authorship 550031
type: Authorship
author rank in publication: 1
linked author: Brugnara, Carlo
linked information resource: Automated reticulocyte counting and measurement of reticulocyte cellular indices. Evaluation of the Miles H*3 blood analyzer.

Authorship 551742
type: Authorship
author rank in publication: 2
linked author: Brugnara, Carlo
linked information resource: In vitro genetic analysis of an erythrocyte determinant of malaria infection.

Authorship 556796
type: Authorship
author rank in publication: 1
linked author: Brugnara, Carlo
linked information resource: Use of reticulocyte cellular indices in the diagnosis and treatment of hematological disorders.

Authorship 558976
type: Authorship
author rank in publication: 6
linked author: Brugnara, Carlo
linked information resource: Characterization of adult alpha- and beta-globin genes in the zebrafish.

Authorship 22881
type: Authorship
author rank in publication: 7
linked author: Brugnara, Carlo
linked information resource: Mutations of conserved arginines in the membrane domain of erythroid band 3 lead to a decrease in membrane-associated band 3 and to the phenotype of hereditary spherocytosis.

Authorship 317528
type: Authorship
author rank in publication: 8
linked author: Brugnara, Carlo
linked information resource: Evidence for a protective role of the Gardos channel against hemolysis in murine spherocytosis.

Authorship 97659
type: Authorship
author rank in publication: 4
linked author: Brugnara, Carlo
linked information resource: An appeal to medical journal editors: the need for a full description of laboratory methods and specimen handling in clinical study reports.

Authorship 510519
type: Authorship
author rank in publication: 4
linked author: Brugnara, Carlo
linked information resource: https://connects.catalyst.harvard.edu/Profiles/profile/977929

Authorship 537134
type: Authorship
author rank in publication: 2
linked author: Brugnara, Carlo
linked information resource: Management training for pathology residents. II. Experience with a focused curriculum.

Authorship 184899
type: Authorship
author rank in publication: 4
linked author: Brugnara, Carlo
linked information resource: Full disclosure in industry-sponsored laboratory medicine research studies: statement by the Consortium of Laboratory Medicine Journal Editors.

Malaria. A forward genetic screen identifies erythrocyte CD55 as essential for Plasmodium falciparum invasion.
PubMed Identifier: 25954012
author list: Egan ES, Jiang RH, Moechtar MA, Barteneva NS, Weekes MP, Nobre LV, Gygi SP, Paulo JA, Frantzreb C, Tani Y, Takahashi J, Watanabe S, Goldberg J, Paul AS, Brugnara C, Root DE, Wiegand RC, Doench JG, Duraisingh MT
published in: Science (New York, N.Y.)
information resource reference: Malaria. A forward genetic screen identifies erythrocyte CD55 as essential for Plasmodium falciparum invasion. Science. 2015 May 08; 348(6235):711-4.
journal title abbreviation: Science
publication date: 2015-05-08T00:00:00
year: 2015
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 29262
type: Authorship
author rank in publication: 4
linked author: Brugnara, Carlo
linked information resource: Full disclosure in industry-sponsored laboratory medicine research studies: statement by the Consortium of Laboratory Medicine Journal Editors.

Authorship 343876
type: Authorship
author rank in publication: 4
linked author: Brugnara, Carlo
linked information resource: An appeal to medical journal editors: the need for a full description of laboratory methods and specimen handling in clinical study reports.

Authorship 416246
type: Authorship
author rank in publication: 3
linked author: Brugnara, Carlo
linked information resource: Inhibition of maxi-K currents in ferret portal vein smooth muscle cells by the antifungal clotrimazole.

Authorship 315444
type: Authorship
author rank in publication: 3
linked author: Brugnara, Carlo
linked information resource: Complement induces a transient increase in membrane permeability in unlysed erythrocytes.

Authorship 32984
type: Authorship
author rank in publication: 1
linked author: Brugnara, Carlo
linked information resource: Oral administration of clotrimazole and blockade of human erythrocyte Ca(++)-activated K+ channel: the imidazole ring is not required for inhibitory activity.

Authorship 214788
type: Authorship
author rank in publication: 5
linked author: Brugnara, Carlo
linked information resource: Quantitative trait loci for baseline erythroid traits.

Authorship 248770
type: Authorship
author rank in publication: 4
linked author: Brugnara, Carlo
linked information resource: Suppression of Fas-FasL coexpression by erythropoietin mediates erythroblast expansion during the erythropoietic stress response in vivo.

Authorship 365996
type: Authorship
author rank in publication: 4
linked author: Brugnara, Carlo
linked information resource: Clotrimazole and efaroxan inhibit red cell Gardos channel independently of imidazoline I1 and I2 binding sites.

Authorship 365621
type: Authorship
author rank in publication: 2
linked author: Brugnara, Carlo
linked information resource: Developing treatment for sickle cell disease.

Authorship 371460
type: Authorship
author rank in publication: 5
linked author: Brugnara, Carlo
linked information resource: Treatment with oral clotrimazole blocks Ca(2+)-activated K+ transport and reverses erythrocyte dehydration in transgenic SAD mice. A model for therapy of sickle cell disease.

Authorship 393530
type: Authorship
author rank in publication: 7
linked author: Brugnara, Carlo
linked information resource: Teaching pediatric laboratory medicine to pathology residents.

Authorship 463068
type: Authorship
author rank in publication: 1
linked author: Brugnara, Carlo
linked information resource: Reticulocyte hemoglobin: an integrated parameter for evaluation of erythropoietic activity.

Authorship 517722
type: Authorship
author rank in publication: 7
linked author: Brugnara, Carlo
linked information resource: Expansion of host cellular niche can drive adaptation of a zoonotic malaria parasite to humans.

Authorship 259919
type: Authorship
author rank in publication: 5
linked author: Brugnara, Carlo
linked information resource: Inhibition of red cell Ca(2+)-activated K+ transport by clotrimazole does not take place via imidazoline binding sites.

Authorship 310095
type: Authorship
author rank in publication: 4
linked author: Brugnara, Carlo
linked information resource: Full-disclosure in industry-sponsored laboratory medicine research studies: statement by the Consortium of Laboratory Medicine Journal Editors.

Authorship 247059
type: Authorship
author rank in publication: 2
linked author: Brugnara, Carlo
linked information resource: The regulation of Na-K cotransport system and essential hypertension.

Authorship 283855
type: Authorship
author rank in publication: 6
linked author: Brugnara, Carlo
linked information resource: Quantitative trait loci for peripheral blood cell counts: a study in baboons.

Authorship 297577
type: Authorship
author rank in publication: 6
linked author: Brugnara, Carlo
linked information resource: Effect of complete protein 4.1R deficiency on ion transport properties of murine erythrocytes.

Authorship 304698
type: Authorship
author rank in publication: 21
linked author: Brugnara, Carlo
linked information resource: Mitochondrial Atpif1 regulates haem synthesis in developing erythroblasts.

Authorship 225471
type: Authorship
author rank in publication: 2
linked author: Brugnara, Carlo
linked information resource: Voltage-activated cation permeability in high-potassium but not low-potassium red blood cells.

Authorship 274269
type: Authorship
author rank in publication: 5
linked author: Brugnara, Carlo
linked information resource: Abnormal regulation of Mg2+ transport via Na/Mg exchanger in sickle erythrocytes.

Authorship 320506
type: Authorship
author rank in publication: 7
linked author: Brugnara, Carlo
linked information resource: Hemoglobin variants and activity of the (K+Cl-) cotransport system in human erythrocytes.

Authorship 340154
type: Authorship
author rank in publication: 5
linked author: Brugnara, Carlo
linked information resource: Combination therapy of erythropoietin, hydroxyurea, and clotrimazole in a beta thalassemic mouse: a model for human therapy.

Authorship 413291
type: Authorship
author rank in publication: 3
linked author: Brugnara, Carlo
linked information resource: Use of recombinant human erythropoietin outside the setting of uremia.

Authorship 430660
type: Authorship
author rank in publication: 9
linked author: Brugnara, Carlo
linked information resource: Protective effects of phosphodiesterase-4 (PDE-4) inhibition in the early phase of pulmonary arterial hypertension in transgenic sickle cell mice.

Authorship 471891
type: Authorship
author rank in publication: 8
linked author: Brugnara, Carlo
linked information resource: Functional characterization and modified rescue of novel AE1 mutation R730C associated with overhydrated cation leak stomatocytosis.

Authorship 551116
type: Authorship
author rank in publication: 16
linked author: Brugnara, Carlo
linked information resource: Loss-of-function and gain-of-function phenotypes of stomatocytosis mutant RhAG F65S.

Authorship 491014
type: Authorship
author rank in publication: 4
linked author: Brugnara, Carlo
linked information resource: Resistance to osmotic lysis in BXD-31 mouse erythrocytes: association with upregulated K-Cl cotransport.

Authorship 789040
type: Authorship
author rank in publication: 2
linked author: Brugnara, Carlo
linked information resource: Clinical utility of reticulocyte parameters.

Authorship 802423
type: Authorship
author rank in publication: 2
linked author: Brugnara, Carlo
linked information resource: Automated hematology analyzers: state of the art.

Authorship 793850
type: Authorship
author rank in publication: 15
linked author: Brugnara, Carlo
linked information resource: Malaria. A forward genetic screen identifies erythrocyte CD55 as essential for Plasmodium falciparum invasion.

Clinical utility of reticulocyte parameters.
PubMed Identifier: 25676377
author list: Piva E, Brugnara C, Spolaore F, Plebani M
published in: Clinics in laboratory medicine
information resource reference: Clinical utility of reticulocyte parameters. Clin Lab Med. 2015 Mar; 35(1):133-63.
journal title abbreviation: Clin Lab Med
publication date: 2014-11-26T00:00:00
year: 2014
type: Academic Article
type: Article
type: Document
type: Information Resource

Automated hematology analyzers: state of the art.
PubMed Identifier: 25676382
author list: Kratz A, Brugnara C
published in: Clinics in laboratory medicine
information resource reference: Automated hematology analyzers: state of the art. Clin Lab Med. 2015 Mar; 35(1):xiii-xiv.
journal title abbreviation: Clin Lab Med
publication date: 2014-11-28T00:00:00
year: 2014
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 317922
type: Authorship
author rank in publication: 4
linked author: Brugnara, Carlo
linked information resource: An appeal to medical journal editors: the need for a full description of laboratory methods and specimen handling in clinical study reports.

Authorship 275649
type: Authorship
author rank in publication: 3
linked author: Brugnara, Carlo
linked information resource: Structural and functional consequences of antigenic modulation of red blood cells with methoxypoly(ethylene glycol).

Authorship 347186
type: Authorship
author rank in publication: 5
linked author: Brugnara, Carlo
linked information resource: Serine/threonine protein phosphatases and regulation of K-Cl cotransport in human erythrocytes.

Authorship 405749
type: Authorship
author rank in publication: 4
linked author: Brugnara, Carlo
linked information resource: Cerebrospinal fluid plasminogen activator inhibitor-1: a prognostic factor in posthaemorrhagic hydrocephalus.

Authorship 405932
type: Authorship
author rank in publication: 5
linked author: Brugnara, Carlo
linked information resource: Full-disclosure in industry-sponsored laboratory medicine research studies: statement by the Consortium of Laboratory Medicine Journal Editors.

Authorship 451184
type: Authorship
author rank in publication: 3
linked author: Brugnara, Carlo
linked information resource: The effect of hemoglobin A and S on the volume- and pH-dependence of K-Cl cotransport in human erythrocyte ghosts.

Authorship 526683
type: Authorship
author rank in publication: 4
linked author: Brugnara, Carlo
linked information resource: Reduced DIDS-sensitive chloride conductance in Ae1-/- mouse erythrocytes.

Authorship 526366
type: Authorship
author rank in publication: 8
linked author: Brugnara, Carlo
linked information resource: Calpain-1 knockout reveals broad effects on erythrocyte deformability and physiology.

Authorship 176314
type: Authorship
author rank in publication: 12
linked author: Brugnara, Carlo
linked information resource: In vivo reduction of erythrocyte oxidant stress in a murine model of beta-thalassemia.

Authorship 809421
type: Authorship
author rank in publication: 12
linked author: Brugnara, Carlo
linked information resource: Dietary ?-3 fatty acids protect against vasculopathy in a transgenic mouse model of sickle cell disease.

Dietary ?-3 fatty acids protect against vasculopathy in a transgenic mouse model of sickle cell disease.
PubMed Identifier: 25934765
author list: Kalish BT, Matte A, Andolfo I, Iolascon A, Weinberg O, Ghigo A, Cimino J, Siciliano A, Hirsch E, Federti E, Puder M, Brugnara C, De Franceschi L
published in: Haematologica
information resource reference: Dietary ?-3 fatty acids protect against vasculopathy in a transgenic mouse model of sickle cell disease. Haematologica. 2015 Jul; 100(7):870-80.
journal title abbreviation: Haematologica
publication date: 2015-05-01T00:00:00
year: 2015
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 328621
type: Authorship
author rank in publication: 10
linked author: Brugnara, Carlo
linked information resource: Missense mutations in the ABCB6 transporter cause dominant familial pseudohyperkalemia.

Authorship 340548
type: Authorship
author rank in publication: 2
linked author: Brugnara, Carlo
linked information resource: Effect of metabolic depletion on the furosemide-sensitive Na and K fluxes in human red cells.

Authorship 345698
type: Authorship
author rank in publication: 9
linked author: Brugnara, Carlo
linked information resource: Oral magnesium supplements reduce erythrocyte dehydration in patients with sickle cell disease.

Authorship 349410
type: Authorship
author rank in publication: 1
linked author: Brugnara, Carlo
linked information resource: Reticulocyte hemoglobin content (CHr): early indicator of iron deficiency and response to therapy.

Authorship 355858
type: Authorship
author rank in publication: 5
linked author: Brugnara, Carlo
linked information resource: Novel AE1 mutations in recessive distal renal tubular acidosis. Loss-of-function is rescued by glycophorin A.

Authorship 366491
type: Authorship
author rank in publication: 4
linked author: Brugnara, Carlo
linked information resource: An appeal to medical journal editors: the need for a full description of laboratory methods and specimen handling in clinical study reports.

Authorship 457515
type: Authorship
author rank in publication: 4
linked author: Brugnara, Carlo
linked information resource: Daily multivitamins with iron to prevent anemia in high-risk infants: a randomized clinical trial.

Authorship 831978
type: Authorship
author rank in publication: 13
linked author: Brugnara, Carlo
linked information resource: Rapamycin improves TIE2-mutated venous malformation in murine model and human subjects.

Authorship 831150
type: Authorship
author rank in publication: 2
linked author: Brugnara, Carlo
linked information resource: Diagnosis of iron-deficient states.

Diagnosis of iron-deficient states.
PubMed Identifier: 26292073
author list: Archer NM, Brugnara C
published in: Critical reviews in clinical laboratory sciences
information resource reference: Diagnosis of iron-deficient states. Crit Rev Clin Lab Sci. 2015; 52(5):256-72.
journal title abbreviation: Crit Rev Clin Lab Sci
publication date: 2015-08-14T00:00:00
year: 2015
type: Academic Article
type: Article
type: Document
type: Information Resource

Rapamycin improves TIE2-mutated venous malformation in murine model and human subjects.
PubMed Identifier: 26258417
author list: Boscolo E, Limaye N, Huang L, Kang KT, Soblet J, Uebelhoer M, Mendola A, Natynki M, Seront E, Dupont S, Hammer J, Legrand C, Brugnara C, Eklund L, Vikkula M, Bischoff J, Boon LM
published in: The Journal of clinical investigation
information resource reference: Rapamycin improves TIE2-mutated venous malformation in murine model and human subjects. J Clin Invest. 2015 Sep; 125(9):3491-504.
journal title abbreviation: J Clin Invest
publication date: 2015-08-10T00:00:00
year: 2015
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 562487
type: Authorship
author rank in publication: 4
linked author: Brugnara, Carlo
linked information resource: [Incidence of retinal and renal complications in arterial hypertension].

Authorship 834756
type: Authorship
author rank in publication: 8
linked author: Brugnara, Carlo
linked information resource: Novel Gardos channel mutations linked to dehydrated hereditary stomatocytosis (xerocytosis).

Authorship 833286
type: Authorship
author rank in publication: 3
linked author: Brugnara, Carlo
linked information resource: 2015 Clinical trials update in sickle cell anemia.

Authorship 835120
type: Authorship
author rank in publication: 4
linked author: Brugnara, Carlo
linked information resource: The utility of the DDAVP challenge test in children with low von Willebrand factor.

Novel Gardos channel mutations linked to dehydrated hereditary stomatocytosis (xerocytosis).
PubMed Identifier: 26178367
author list: Andolfo I, Russo R, Manna F, Shmukler BE, Gambale A, Vitiello G, De Rosa G, Brugnara C, Alper SL, Snyder LM, Iolascon A
published in: American journal of hematology
information resource reference: Novel Gardos channel mutations linked to dehydrated hereditary stomatocytosis (xerocytosis). Am J Hematol. 2015 Oct; 90(10):921-6.
journal title abbreviation: Am J Hematol
publication date: 2015-10-01T00:00:00
year: 2015
type: Academic Article
type: Article
type: Document
type: Information Resource

The utility of the DDAVP challenge test in children with low von Willebrand factor.
PubMed Identifier: 25733073
author list: Archer NM, Samnaliev M, Grace R, Brugnara C
published in: British journal of haematology
information resource reference: The utility of the DDAVP challenge test in children with low von Willebrand factor. Br J Haematol. 2015 Sep; 170(6):884-6.
journal title abbreviation: Br J Haematol
publication date: 2015-03-02T00:00:00
year: 2015
type: Academic Article
type: Article
type: Document
type: Information Resource

2015 Clinical trials update in sickle cell anemia.
PubMed Identifier: 26178236
author list: Archer N, Galacteros F, Brugnara C
published in: American journal of hematology
information resource reference: 2015 Clinical trials update in sickle cell anemia. Am J Hematol. 2015 Oct; 90(10):934-50.
journal title abbreviation: Am J Hematol
publication date: 2015-10-01T00:00:00
year: 2015
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 88724
type: Authorship
author rank in publication: 4
linked author: Brugnara, Carlo
linked information resource: Full-disclosure in industry-sponsored laboratory medicine research studies: Statement by the Consortium of Laboratory Medicine Journal Editors.

Authorship 385097
type: Authorship
author rank in publication: 9
linked author: Brugnara, Carlo
linked information resource: cDNA cloning and functional characterization of the mouse Ca2+-gated K+ channel, mIK1. Roles in regulatory volume decrease and erythroid differentiation.

Authorship 494262
type: Authorship
author rank in publication: 1
linked author: Brugnara, Carlo
linked information resource: Management training for pathology residents. I. Results of a national survey.

Authorship 435008
type: Authorship
author rank in publication: 1
linked author: Brugnara, Carlo
linked information resource: Regulation of cation content and cell volume in hemoglobin erythrocytes from patients with homozygous hemoglobin C disease.

Authorship 855427
type: Authorship
author rank in publication: 7
linked author: Brugnara, Carlo
linked information resource: The Clinically Tested Gardos Channel Inhibitor Senicapoc Exhibits Antimalarial Activity.

The Clinically Tested Gardos Channel Inhibitor Senicapoc Exhibits Antimalarial Activity.
PubMed Identifier: 26459896
author list: Tubman VN, Mejia P, Shmukler BE, Bei AK, Alper SL, Mitchell JR, Brugnara C, Duraisingh MT
published in: Antimicrobial agents and chemotherapy
information resource reference: The Clinically Tested Gardos Channel Inhibitor Senicapoc Exhibits Antimalarial Activity. Antimicrob Agents Chemother. 2016 01; 60(1):613-6.
journal title abbreviation: Antimicrob Agents Chemother
publication date: 2015-10-12T00:00:00
year: 2015
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 458411
type: Authorship
author rank in publication: 1
linked author: Brugnara, Carlo
linked information resource: Novel therapies for prevention of erythrocyte dehydration in sickle cell anemia.

Authorship 463668
type: Authorship
author rank in publication: 1
linked author: Brugnara, Carlo
linked information resource: Inhibition of K transport by divalent cations in sickle erythrocytes.

Authorship 474647
type: Authorship
author rank in publication: 1
linked author: Brugnara, Carlo
linked information resource: A hematologic "gold standard" for iron-deficient states?

Authorship 475615
type: Authorship
author rank in publication: 3
linked author: Brugnara, Carlo
linked information resource: Automated flow cytometric analysis of blood cells in cerebrospinal fluid: analytic performance.

Authorship 514367
type: Authorship
author rank in publication: 9
linked author: Brugnara, Carlo
linked information resource: The effect of dietary magnesium supplementation on the cellular abnormalities of erythrocytes in patients with beta thalassemia intermedia.

Authorship 858604
type: Authorship
author rank in publication: 14
linked author: Brugnara, Carlo
linked information resource: Targeted Application of Human Genetic Variation Can Improve Red Blood Cell Production from Stem Cells.

Authorship 860638
type: Authorship
author rank in publication: 1
linked author: Brugnara, Carlo
linked information resource: The American Journal of Hematology turns 40.

The American Journal of Hematology turns 40.
PubMed Identifier: 26575091
author list: Brugnara C
published in: American journal of hematology
information resource reference: The American Journal of Hematology turns 40. Am J Hematol. 2016 Jan; 91(1):4.
journal title abbreviation: Am J Hematol
publication date: 2016-01-01T00:00:00
year: 2016
type: Academic Article
type: Article
type: Document
type: Information Resource

Targeted Application of Human Genetic Variation Can Improve Red Blood Cell Production from Stem Cells.
PubMed Identifier: 26607381
author list: Giani FC, Fiorini C, Wakabayashi A, Ludwig LS, Salem RM, Jobaliya CD, Regan SN, Ulirsch JC, Liang G, Steinberg-Shemer O, Guo MH, Esko T, Tong W, Brugnara C, Hirschhorn JN, Weiss MJ, Zon LI, Chou ST, French DL, Musunuru K, Sankaran VG
published in: Cell stem cell
information resource reference: Targeted Application of Human Genetic Variation Can Improve Red Blood Cell Production from Stem Cells. Cell Stem Cell. 2016 Jan 07; 18(1):73-78.
journal title abbreviation: Cell Stem Cell
publication date: 2015-10-22T00:00:00
year: 2015
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 62418
type: Authorship
author rank in publication: 1
linked author: Brugnara, Carlo
linked information resource: Red cell indices in classification and treatment of anemias: from M.M. Wintrobes's original 1934 classification to the third millennium.

Authorship 72275
type: Authorship
author rank in publication: 1
linked author: Brugnara, Carlo
linked information resource: Therapeutic strategies for prevention of sickle cell dehydration.

Authorship 369151
type: Authorship
author rank in publication: 2
linked author: Brugnara, Carlo
linked information resource: Ca2+-activated K+ efflux limits complement-mediated lysis of human erythrocytes.

Authorship 45696
type: Authorship
author rank in publication: 6
linked author: Brugnara, Carlo
linked information resource: https://connects.catalyst.harvard.edu/Profiles/profile/775189

Authorship 572071
type: Authorship
author rank in publication: 7
linked author: Brugnara, Carlo
linked information resource: Headpiece domain of dematin is required for the stability of the erythrocyte membrane.

Assistant Professor
sort order: 2
type: Faculty Rank

Associate Professor
sort order: 1
type: Faculty Rank

Full Professor
sort order: 0
type: Faculty Rank

Instructor
sort order: 4
type: Faculty Rank

Other Faculty
sort order: 5
type: Faculty Rank

Authorship 67533
type: Authorship
author rank in publication: 12
linked author: Brugnara, Carlo
linked information resource: Positional cloning of zebrafish ferroportin1 identifies a conserved vertebrate iron exporter.

Authorship 82305
type: Authorship
author rank in publication: 3
linked author: Brugnara, Carlo
linked information resource: Modulation of Gardos channel activity by cytokines in sickle erythrocytes.

Authorship 5525
type: Authorship
author rank in publication: 3
linked author: Brugnara, Carlo
linked information resource: Phase I study of magnesium pidolate in combination with hydroxycarbamide for children with sickle cell anaemia.

Authorship 554196
type: Authorship
author rank in publication: 1
linked author: Brugnara, Carlo
linked information resource: Effect of irradiation on red cell cation content and transport.

Authorship 891814
type: Authorship
author rank in publication: 3
linked author: Brugnara, Carlo
linked information resource: Clinical Applications of Automated Reticulocyte Indices.

Clinical Applications of Automated Reticulocyte Indices.
PubMed Identifier: 27416481
author list: D'onofrio G, Zini G, Brugnara C
published in: Hematology (Amsterdam, Netherlands)
information resource reference: Clinical Applications of Automated Reticulocyte Indices. Hematology. 1998; 3(2):165-76.
journal title abbreviation: Hematology
publication date: 1998-01-01T00:00:00
year: 1998
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 895274
type: Authorship
author rank in publication: 10
linked author: Brugnara, Carlo
linked information resource: Functional characterization of novel ABCB6 mutations and their clinical implications in familial pseudohyperkalemia.

Functional characterization of novel ABCB6 mutations and their clinical implications in familial pseudohyperkalemia.
PubMed Identifier: 27151991
author list: Andolfo I, Russo R, Manna F, De Rosa G, Gambale A, Zouwail S, Detta N, Pardo CL, Alper SL, Brugnara C, Sharma AK, De Franceschi L, Iolascon A
published in: Haematologica
information resource reference: Functional characterization of novel ABCB6 mutations and their clinical implications in familial pseudohyperkalemia. Haematologica. 2016 08; 101(8):909-17.
journal title abbreviation: Haematologica
publication date: 2016-05-05T00:00:00
year: 2016
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 55278
type: Authorship
author rank in publication: 4
linked author: Brugnara, Carlo
linked information resource: Targeted disruption of the beta adducin gene (Add2) causes red blood cell spherocytosis in mice.

Authorship 188394
type: Authorship
author rank in publication: 2
linked author: Brugnara, Carlo
linked information resource: Multiple arterial stenoses in chronic ergot toxicity.

Authorship 67113
type: Authorship
author rank in publication: 2
linked author: Brugnara, Carlo
linked information resource: Genetic influences on peripheral blood cell counts: a study in baboons.

Authorship 526653
type: Authorship
author rank in publication: 1
linked author: Brugnara, Carlo
linked information resource: [Physiopathology of erythrocyte membrane transport].

Authorship 563239
type: Authorship
author rank in publication: 4
linked author: Brugnara, Carlo
linked information resource: An appeal to medical journal editors: the need for a full description of laboratory methods and specimen handling in clinical study reports.

COMPREHENSIVE SICKLE CELL CENTER
end date: 2004-03-31
principal investigator name: STEINBERG, MARTIN H.
start date: 1977-04-01
type: Grant
sponsor award id: P60HL015157

General Clinical Research Center
end date: 2009-03-31
principal investigator name: MANDELL, JAMES WILLIAM
start date: 1983-01-01
type: Grant
sponsor award id: M01RR002172

ABNORMAL HEMOGLOBINS, CATIONS, AND VOLUME IN RED CELLS
end date: 1989-03-31
principal investigator name: BRUGNARA, CARLO
start date: 1986-04-01
type: Grant
sponsor award id: R01HL036076

Magnesium and Sickle Cell Disease
end date: 2007-06-30
principal investigator name: BRUGNARA, CARLO
start date: 1995-09-30
type: Grant
sponsor award id: R01DK050422

Genetic Determinants of Erythrocyte Hydration
end date: 2011-03-31
principal investigator name: BRUGNARA, CARLO
start date: 2006-04-01
type: Grant
sponsor award id: R01HL081497

Principal Investigator
type: Researcher Role
researcher role of: Brugnara, Carlo
contributes to: Magnesium and Sickle Cell Disease

Co-Principal Investigator
type: Researcher Role
researcher role of: Brugnara, Carlo
contributes to: General Clinical Research Center

Co-Principal Investigator
type: Researcher Role
researcher role of: Brugnara, Carlo
contributes to: COMPREHENSIVE SICKLE CELL CENTER

Principal Investigator
type: Researcher Role
researcher role of: Brugnara, Carlo
contributes to: ABNORMAL HEMOGLOBINS, CATIONS, AND VOLUME IN RED CELLS

Principal Investigator
type: Researcher Role
researcher role of: Brugnara, Carlo
contributes to: Genetic Determinants of Erythrocyte Hydration

Authorship 7697
type: Authorship
author rank in publication: 8
linked author: Brugnara, Carlo
linked information resource: Oral magnesium pidolate: effects of long-term administration in patients with sickle cell disease.

Authorship 360132
type: Authorship
author rank in publication: 1
linked author: Brugnara, Carlo
linked information resource: Sickle cell disease: from membrane pathophysiology to novel therapies for prevention of erythrocyte dehydration.

Authorship 387706
type: Authorship
author rank in publication: 4
linked author: Brugnara, Carlo
linked information resource: [Frequency and sex and age distribution of cardiopathy in arterial hypertension].

Authorship 920811
type: Authorship
author rank in publication: 6
linked author: Brugnara, Carlo
linked information resource: Diagnosis of iron deficiency anemia using density-based fractionation of red blood cells.

Diagnosis of iron deficiency anemia using density-based fractionation of red blood cells.
PubMed Identifier: 27713998
author list: Hennek JW, Kumar AA, Wiltschko AB, Patton MR, Lee SY, Brugnara C, Adams RP, Whitesides GM
published in: Lab on a chip
information resource reference: Diagnosis of iron deficiency anemia using density-based fractionation of red blood cells. Lab Chip. 2016 10 05; 16(20):3929-3939.
journal title abbreviation: Lab Chip
publication date: 2016-10-05T00:00:00
year: 2016
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 290266
type: Authorship
author rank in publication: 13
linked author: Brugnara, Carlo
linked information resource: PTPepsilon has a critical role in signaling transduction pathways and phosphoprotein network topology in red cells.

Authorship 365318
type: Authorship
author rank in publication: 1
linked author: Brugnara, Carlo
linked information resource: Characteristics of the volume- and chloride-dependent K transport in human erythrocytes homozygous for hemoglobin C.

Authorship 464231
type: Authorship
author rank in publication: 2
linked author: Brugnara, Carlo
linked information resource: The Li+-Na+ exchange and Na+-K+-Cl- cotransport systems in essential hypertension.

Authorship 550059
type: Authorship
author rank in publication: 6
linked author: Brugnara, Carlo
linked information resource: Oxidative damage and erythrocyte membrane transport abnormalities in thalassemias.

Authorship 9938
type: Authorship
author rank in publication: 3
linked author: Brugnara, Carlo
linked information resource: Erythropoietin, iron, and erythropoiesis.

Modulation of erythrocyte potassium chloride cotransport, potassium content, and density by dietary magnesium intake in transgenic SAD mouse.
PubMed Identifier: 8839870
author list: De Franceschi L, Beuzard Y, Jouault H, Brugnara C
published in: Blood
information resource reference: Modulation of erythrocyte potassium chloride cotransport, potassium content, and density by dietary magnesium intake in transgenic SAD mouse. Blood. 1996 Oct 01; 88(7):2738-44.
journal title abbreviation: Blood
publication date: 1996-10-01T00:00:00
year: 1996
type: Academic Article
type: Article
type: Document
type: Information Resource

Use of recombinant human erythropoietin outside the setting of uremia.
PubMed Identifier: 9192747
author list: Cazzola M, Mercuriali F, Brugnara C
published in: Blood
information resource reference: Use of recombinant human erythropoietin outside the setting of uremia. Blood. 1997 Jun 15; 89(12):4248-67.
journal title abbreviation: Blood
publication date: 1997-06-15T00:00:00
year: 1997
type: Academic Article
type: Article
type: Document
type: Information Resource

Dietary magnesium supplementation ameliorates anemia in a mouse model of beta-thalassemia.
PubMed Identifier: 9242563
author list: De Franceschi L, Brugnara C, Beuzard Y
published in: Blood
information resource reference: Dietary magnesium supplementation ameliorates anemia in a mouse model of beta-thalassemia. Blood. 1997 Aug 01; 90(3):1283-90.
journal title abbreviation: Blood
publication date: 1997-08-01T00:00:00
year: 1997
type: Academic Article
type: Article
type: Document
type: Information Resource

Cerebrospinal fluid plasminogen activator inhibitor-1: a prognostic factor in posthaemorrhagic hydrocephalus.
PubMed Identifier: 9343282
author list: Hansen A, Whitelaw A, Lapp C, Brugnara C
published in: Acta paediatrica (Oslo, Norway : 1992)
information resource reference: Cerebrospinal fluid plasminogen activator inhibitor-1: a prognostic factor in posthaemorrhagic hydrocephalus. Acta Paediatr. 1997 Sep; 86(9):995-8.
journal title abbreviation: Acta Paediatr
publication date: 1997-09-01T00:00:00
year: 1997
type: Academic Article
type: Article
type: Document
type: Information Resource

[Physiopathology of erythrocyte membrane transport].
PubMed Identifier: 1752514
author list: Brugnara C
published in: Haematologica
information resource reference: [Physiopathology of erythrocyte membrane transport]. Haematologica. 1991 Jun; 76 Suppl 3:191-8.
journal title abbreviation: Haematologica
publication date: 1991-06-01T00:00:00
year: 1991
type: Academic Article
type: Article
type: Document
type: Information Resource

Iron deficiency and erythropoiesis: new diagnostic approaches.
PubMed Identifier: 14500582
author list: Brugnara C
published in: Clinical chemistry
information resource reference: Iron deficiency and erythropoiesis: new diagnostic approaches. Clin Chem. 2003 Oct; 49(10):1573-8.
journal title abbreviation: Clin Chem
publication date: 2003-10-01T00:00:00
year: 2003
type: Academic Article
type: Article
type: Document
type: Information Resource

Genetic influences on peripheral blood cell counts: a study in baboons.
PubMed Identifier: 15870178
author list: Mahaney MC, Brugnara C, Lease LR, Platt OS
published in: Blood
information resource reference: Genetic influences on peripheral blood cell counts: a study in baboons. Blood. 2005 Aug 15; 106(4):1210-4.
journal title abbreviation: Blood
publication date: 2005-05-03T00:00:00
year: 2005
type: Academic Article
type: Article
type: Document
type: Information Resource

Erythropoietin, iron, and erythropoiesis.
PubMed Identifier: 10910892
author list: Goodnough LT, Skikne B, Brugnara C
published in: Blood
information resource reference: Erythropoietin, iron, and erythropoiesis. Blood. 2000 Aug 01; 96(3):823-33.
journal title abbreviation: Blood
publication date: 2000-08-01T00:00:00
year: 2000
type: Academic Article
type: Article
type: Document
type: Information Resource

Developing treatment for sickle cell disease.
PubMed Identifier: 11996646
author list: Steinberg MH, Brugnara C
published in: Expert opinion on investigational drugs
information resource reference: Developing treatment for sickle cell disease. Expert Opin Investig Drugs. 2002 May; 11(5):645-59.
journal title abbreviation: Expert Opin Investig Drugs
publication date: 2002-05-01T00:00:00
year: 2002
type: Academic Article
type: Article
type: Document
type: Information Resource

Cellular effects of hydroxyurea in Hb SC disease.
PubMed Identifier: 9326175
author list: Steinberg MH, Nagel RL, Brugnara C
published in: British journal of haematology
information resource reference: Cellular effects of hydroxyurea in Hb SC disease. Br J Haematol. 1997 Sep; 98(4):838-44.
journal title abbreviation: Br J Haematol
publication date: 1997-09-01T00:00:00
year: 1997
type: Academic Article
type: Article
type: Document
type: Information Resource

Structural and functional consequences of antigenic modulation of red blood cells with methoxypoly(ethylene glycol).
PubMed Identifier: 10068687
author list: Murad KL, Mahany KL, Brugnara C, Kuypers FA, Eaton JW, Scott MD
published in: Blood
information resource reference: Structural and functional consequences of antigenic modulation of red blood cells with methoxypoly(ethylene glycol). Blood. 1999 Mar 15; 93(6):2121-7.
journal title abbreviation: Blood
publication date: 1999-03-15T00:00:00
year: 1999
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 963992
type: Authorship
author rank in publication: 2
linked author: Brugnara, Carlo
linked information resource: Diagnosis of iron-deficient states.

Diagnosis of iron-deficient states.
PubMed Identifier: 26274917
author list: Archer NM, Brugnara C
published in: Critical reviews in clinical laboratory sciences
information resource reference: Diagnosis of iron-deficient states. Crit Rev Clin Lab Sci. 2015 Aug 14; 1-17.
journal title abbreviation: Crit Rev Clin Lab Sci
publication date: 2015-08-14T00:00:00
year: 2015
type: Academic Article
type: Article
type: Document
type: Information Resource

Endothelins activate Ca(2+)-gated K(+) channels via endothelin B receptors in CD-1 mouse erythrocytes.
PubMed Identifier: 10516105
author list: Rivera A, Rotter MA, Brugnara C
published in: The American journal of physiology
information resource reference: Endothelins activate Ca(2+)-gated K(+) channels via endothelin B receptors in CD-1 mouse erythrocytes. Am J Physiol. 1999 10; 277(4):C746-54.
journal title abbreviation: Am J Physiol
publication date: 1999-10-01T00:00:00
year: 1999
type: Academic Article
type: Article
type: Document
type: Information Resource

Mouse K-Cl cotransporter KCC1: cloning, mapping, pathological expression, and functional regulation.
PubMed Identifier: 10564083
author list: Su W, Shmukler BE, Chernova MN, Stuart-Tilley AK, de Franceschi L, Brugnara C, Alper SL
published in: The American journal of physiology
information resource reference: Mouse K-Cl cotransporter KCC1: cloning, mapping, pathological expression, and functional regulation. Am J Physiol. 1999 11; 277(5):C899-912.
journal title abbreviation: Am J Physiol
publication date: 1999-11-01T00:00:00
year: 1999
type: Academic Article
type: Article
type: Document
type: Information Resource

Formation of dense erythrocytes in SAD mice exposed to chronic hypoxia: evaluation of different therapeutic regimens and of a combination of oral clotrimazole and magnesium therapies.
PubMed Identifier: 10590075
author list: De Franceschi L, Brugnara C, Rouyer-Fessard P, Jouault H, Beuzard Y
published in: Blood
information resource reference: Formation of dense erythrocytes in SAD mice exposed to chronic hypoxia: evaluation of different therapeutic regimens and of a combination of oral clotrimazole and magnesium therapies. Blood. 1999 Dec 15; 94(12):4307-13.
journal title abbreviation: Blood
publication date: 1999-12-15T00:00:00
year: 1999
type: Academic Article
type: Article
type: Document
type: Information Resource

Maximum urine concentrating ability in children with Hb SC disease: effects of hydroxyurea.
PubMed Identifier: 10815787
author list: Iyer R, Baliga R, Nagel RL, Brugnara C, Kirchner K, Hogan S, Steinberg MH
published in: American journal of hematology
information resource reference: Maximum urine concentrating ability in children with Hb SC disease: effects of hydroxyurea. Am J Hematol. 2000 May; 64(1):47-52.
journal title abbreviation: Am J Hematol
publication date: 2000-05-01T00:00:00
year: 2000
type: Academic Article
type: Article
type: Document
type: Information Resource

Oral magnesium supplements reduce erythrocyte dehydration in patients with sickle cell disease.
PubMed Identifier: 9312186
author list: De Franceschi L, Bachir D, Galacteros F, Tchernia G, Cynober T, Alper S, Platt O, Beuzard Y, Brugnara C
published in: The Journal of clinical investigation
information resource reference: Oral magnesium supplements reduce erythrocyte dehydration in patients with sickle cell disease. J Clin Invest. 1997 Oct 01; 100(7):1847-52.
journal title abbreviation: J Clin Invest
publication date: 1997-10-01T00:00:00
year: 1997
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 970227
type: Authorship
author rank in publication: 9
linked author: Brugnara, Carlo
linked information resource: Variant-aware saturating mutagenesis using multiple Cas9 nucleases identifies regulatory elements at trait-associated loci.

Variant-aware saturating mutagenesis using multiple Cas9 nucleases identifies regulatory elements at trait-associated loci.
PubMed Identifier: 28218758
author list: Canver MC, Lessard S, Pinello L, Wu Y, Ilboudo Y, Stern EN, Needleman AJ, Galactéros F, Brugnara C, Kutlar A, McKenzie C, Reid M, Chen DD, Das PP, A Cole M, Zeng J, Kurita R, Nakamura Y, Yuan GC, Lettre G, Bauer DE, Orkin SH
published in: Nature genetics
information resource reference: Variant-aware saturating mutagenesis using multiple Cas9 nucleases identifies regulatory elements at trait-associated loci. Nat Genet. 2017 Apr; 49(4):625-634.
journal title abbreviation: Nat Genet
publication date: 2017-02-20T00:00:00
year: 2017
type: Academic Article
type: Article
type: Document
type: Information Resource

Reticulocyte cellular indices: a new approach in the diagnosis of anemias and monitoring of erythropoietic function.
PubMed Identifier: 10811141
author list: Brugnara C
published in: Critical reviews in clinical laboratory sciences
information resource reference: Reticulocyte cellular indices: a new approach in the diagnosis of anemias and monitoring of erythropoietic function. Crit Rev Clin Lab Sci. 2000 Apr; 37(2):93-130.
journal title abbreviation: Crit Rev Clin Lab Sci
publication date: 2000-04-01T00:00:00
year: 2000
type: Academic Article
type: Article
type: Document
type: Information Resource

The antifungal antibiotic, clotrimazole, inhibits Cl- secretion by polarized monolayers of human colonic epithelial cells.
PubMed Identifier: 8903326
author list: Rufo PA, Jiang L, Moe SJ, Brugnara C, Alper SL, Lencer WI
published in: The Journal of clinical investigation
information resource reference: The antifungal antibiotic, clotrimazole, inhibits Cl- secretion by polarized monolayers of human colonic epithelial cells. J Clin Invest. 1996 Nov 01; 98(9):2066-75.
journal title abbreviation: J Clin Invest
publication date: 1996-11-01T00:00:00
year: 1996
type: Academic Article
type: Article
type: Document
type: Information Resource

Erythrocyte membrane transport physiology.
PubMed Identifier: 9107529
author list: Brugnara C
published in: Current opinion in hematology
information resource reference: Erythrocyte membrane transport physiology. Curr Opin Hematol. 1997 Mar; 4(2):122-7.
journal title abbreviation: Curr Opin Hematol
publication date: 1997-03-01T00:00:00
year: 1997
type: Academic Article
type: Article
type: Document
type: Information Resource

Reticulocyte hemoglobin: an integrated parameter for evaluation of erythropoietic activity.
PubMed Identifier: 9260753
author list: Brugnara C, Zelmanovic D, Sorette M, Ballas SK, Platt O
published in: American journal of clinical pathology
information resource reference: Reticulocyte hemoglobin: an integrated parameter for evaluation of erythropoietic activity. Am J Clin Pathol. 1997 Aug; 108(2):133-42.
journal title abbreviation: Am J Clin Pathol
publication date: 1997-08-01T00:00:00
year: 1997
type: Academic Article
type: Article
type: Document
type: Information Resource

The effect of dietary magnesium supplementation on the cellular abnormalities of erythrocytes in patients with beta thalassemia intermedia.
PubMed Identifier: 9549922
author list: De Franceschi L, Cappellini MD, Graziadei G, Manzato F, Olivieri O, Corrocher R, Fiorelli G, Beuzard Y, Brugnara C
published in: Haematologica
information resource reference: The effect of dietary magnesium supplementation on the cellular abnormalities of erythrocytes in patients with beta thalassemia intermedia. Haematologica. 1998 Feb; 83(2):118-25.
journal title abbreviation: Haematologica
publication date: 1998-02-01T00:00:00
year: 1998
type: Academic Article
type: Article
type: Document
type: Information Resource

Fetal anemia and apoptosis of red cell progenitors in Stat5a-/-5b-/- mice: a direct role for Stat5 in Bcl-X(L) induction.
PubMed Identifier: 10428030
author list: Socolovsky M, Fallon AE, Wang S, Brugnara C, Lodish HF
published in: Cell
information resource reference: Fetal anemia and apoptosis of red cell progenitors in Stat5a-/-5b-/- mice: a direct role for Stat5 in Bcl-X(L) induction. Cell. 1999 Jul 23; 98(2):181-91.
journal title abbreviation: Cell
publication date: 1999-07-23T00:00:00
year: 1999
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 971289
type: Authorship
author rank in publication: 7
linked author: Brugnara, Carlo
linked information resource: Erythrocytes from hereditary xerocytosis patients heterozygous for KCNN4 V282M exhibit increased spontaneous Gardos channel-like activity inhibited by senicapoc.

Erythrocytes from hereditary xerocytosis patients heterozygous for KCNN4 V282M exhibit increased spontaneous Gardos channel-like activity inhibited by senicapoc.
PubMed Identifier: 28295477
author list: Rivera A, Vandorpe DH, Shmukler BE, Gallagher DR, Fikry CC, Kuypers FA, Brugnara C, Snyder LM, Alper SL
published in: American journal of hematology
information resource reference: Erythrocytes from hereditary xerocytosis patients heterozygous for KCNN4 V282M exhibit increased spontaneous Gardos channel-like activity inhibited by senicapoc. Am J Hematol. 2017 06; 92(6):E108-E110.
journal title abbreviation: Am J Hematol
publication date: 2017-04-29T00:00:00
year: 2017
type: Academic Article
type: Article
type: Document
type: Information Resource

Failure of red blood cell maturation in mice with defects in the high-density lipoprotein receptor SR-BI.
PubMed Identifier: 11861300
author list: Holm TM, Braun A, Trigatti BL, Brugnara C, Sakamoto M, Krieger M, Andrews NC
published in: Blood
information resource reference: Failure of red blood cell maturation in mice with defects in the high-density lipoprotein receptor SR-BI. Blood. 2002 Mar 01; 99(5):1817-24.
journal title abbreviation: Blood
publication date: 2002-03-01T00:00:00
year: 2002
type: Academic Article
type: Article
type: Document
type: Information Resource

300 Longwood Ave
type: Address
address line 1: Childrens Hospital
address line 2: Lab Medicine
address line 3: 300 Longwood Ave
city: Boston
postal code: 02115
state or province: MA

Reinterpretation of the RACTK1 K+ channel.
PubMed Identifier: 9038842
author list: Shmukler B, Sun T, Brugnara C, Alper SL
published in: The American journal of physiology
information resource reference: Reinterpretation of the RACTK1 K+ channel. Am J Physiol. 1997 Jan; 272(1 Pt 1):C350-4.
journal title abbreviation: Am J Physiol
publication date: 1997-01-01T00:00:00
year: 1997
type: Academic Article
type: Article
type: Document
type: Information Resource

https://connects.catalyst.harvard.edu/Profiles/profile/775189
PubMed Identifier: 9399958
author list: Rufo PA, Merlin D, Riegler M, Ferguson-Maltzman MH, Dickinson BL, Brugnara C, Alper SL, Lencer WI
published in: The Journal of clinical investigation
information resource reference: The antifungal antibiotic, clotrimazole, inhibits chloride secretion by human intestinal T84 cells via blockade of distinct basolateral K+ conductances. Demonstration of efficacy in intact rabbit colon and in an in vivo mouse model of cholera. J Clin Invest. 1997 Dec 15; 100(12):3111-20.
journal title abbreviation: J Clin Invest
publication date: 1997-12-15T00:00:00
year: 1997
type: Academic Article
type: Article
type: Document
type: Information Resource
label: The antifungal antibiotic, clotrimazole, inhibits chloride secretion by human intestinal T84 cells via blockade of distinct basolateral K+ conductances. Demonstration of efficacy in intact rabbit colon and in an in vivo mouse model of cholera.

Flow-cytometric analysis of erythrocytes and reticulocytes in congenital dyserythropoietic anaemia type II (CDA II): value in differential diagnosis with hereditary spherocytosis.
PubMed Identifier: 11422224
author list: Danise P, Amendola G, Nobili B, Perrotta S, Miraglia Del Giudice E, Matarese SM, Iolascon A, Brugnara C
published in: Clinical and laboratory haematology
information resource reference: Flow-cytometric analysis of erythrocytes and reticulocytes in congenital dyserythropoietic anaemia type II (CDA II): value in differential diagnosis with hereditary spherocytosis. Clin Lab Haematol. 2001 Feb; 23(1):7-13.
journal title abbreviation: Clin Lab Haematol
publication date: 2001-02-01T00:00:00
year: 2001
type: Academic Article
type: Article
type: Document
type: Information Resource

Ineffective erythropoiesis in Stat5a(-/-)5b(-/-) mice due to decreased survival of early erythroblasts.
PubMed Identifier: 11719363
author list: Socolovsky M, Nam H, Fleming MD, Haase VH, Brugnara C, Lodish HF
published in: Blood
information resource reference: Ineffective erythropoiesis in Stat5a(-/-)5b(-/-) mice due to decreased survival of early erythroblasts. Blood. 2001 Dec 01; 98(12):3261-73.
journal title abbreviation: Blood
publication date: 2001-12-01T00:00:00
year: 2001
type: Academic Article
type: Article
type: Document
type: Information Resource

Protective effects of S-nitrosoalbumin on lung injury induced by hypoxia-reoxygenation in mouse model of sickle cell disease.
PubMed Identifier: 16603592
author list: de Franceschi L, Malpeli G, Scarpa A, Janin A, Muchitsch EM, Roncada P, Leboeuf C, Corrocher R, Beuzard Y, Brugnara C
published in: American journal of physiology. Lung cellular and molecular physiology
information resource reference: Protective effects of S-nitrosoalbumin on lung injury induced by hypoxia-reoxygenation in mouse model of sickle cell disease. Am J Physiol Lung Cell Mol Physiol. 2006 Sep; 291(3):L457-65.
journal title abbreviation: Am J Physiol Lung Cell Mol Physiol
publication date: 2006-04-07T00:00:00
year: 2006
type: Academic Article
type: Article
type: Document
type: Information Resource

Teaching pediatric laboratory medicine to pathology residents.
PubMed Identifier: 16831030
author list: Pysher TJ, Bach PR, Geaghan SM, Hamilton MS, Laposata M, Lockitch G, Brugnara C, Coffin CM, Pasquali M, Rinaldo P, Roberts WL, Rutledge JC, Ashwood ER, Blaylock RC, Campos JM, Goldsmith B, Jones PM, Lim M, Meikle AW, Perkins SL, Perry DA, Petti CA, Rogers BB, Steele PE, Weiss RL, Woods G
published in: Archives of pathology & laboratory medicine
information resource reference: Teaching pediatric laboratory medicine to pathology residents. Arch Pathol Lab Med. 2006 Jul; 130(7):1031-8.
journal title abbreviation: Arch Pathol Lab Med
publication date: 2006-07-01T00:00:00
year: 2006
type: Academic Article
type: Article
type: Document
type: Information Resource

The antifungal imidazole clotrimazole and its major in vivo metabolite are potent blockers of the calcium-activated potassium channel in murine erythroleukemia cells.
PubMed Identifier: 9151659
author list: Rittenhouse AR, Vandorpe DH, Brugnara C, Alper SL
published in: The Journal of membrane biology
information resource reference: The antifungal imidazole clotrimazole and its major in vivo metabolite are potent blockers of the calcium-activated potassium channel in murine erythroleukemia cells. J Membr Biol. 1997 May 15; 157(2):177-91.
journal title abbreviation: J Membr Biol
publication date: 1997-05-15T00:00:00
year: 1997
type: Academic Article
type: Article
type: Document
type: Information Resource

cDNA cloning and functional characterization of the mouse Ca2+-gated K+ channel, mIK1. Roles in regulatory volume decrease and erythroid differentiation.
PubMed Identifier: 9705284
author list: Vandorpe DH, Shmukler BE, Jiang L, Lim B, Maylie J, Adelman JP, de Franceschi L, Cappellini MD, Brugnara C, Alper SL
published in: The Journal of biological chemistry
information resource reference: cDNA cloning and functional characterization of the mouse Ca2+-gated K+ channel, mIK1. Roles in regulatory volume decrease and erythroid differentiation. J Biol Chem. 1998 Aug 21; 273(34):21542-53.
journal title abbreviation: J Biol Chem
publication date: 1998-08-21T00:00:00
year: 1998
type: Academic Article
type: Article
type: Document
type: Information Resource

Deferiprone therapy in homozygous human beta-thalassemia removes erythrocyte membrane free iron and reduces KCl cotransport activity.
PubMed Identifier: 10385483
author list: de Franceschi L, Shalev O, Piga A, Collell M, Olivieri O, Corrocher R, Hebbel RP, Brugnara C
published in: The Journal of laboratory and clinical medicine
information resource reference: Deferiprone therapy in homozygous human beta-thalassemia removes erythrocyte membrane free iron and reduces KCl cotransport activity. J Lab Clin Med. 1999 Jan; 133(1):64-9.
journal title abbreviation: J Lab Clin Med
publication date: 1999-01-01T00:00:00
year: 1999
type: Academic Article
type: Article
type: Document
type: Information Resource

Anion exchanger 1 (band 3) is required to prevent erythrocyte membrane surface loss but not to form the membrane skeleton.
PubMed Identifier: 8808627
author list: Peters LL, Shivdasani RA, Liu SC, Hanspal M, John KM, Gonzalez JM, Brugnara C, Gwynn B, Mohandas N, Alper SL, Orkin SH, Lux SE
published in: Cell
information resource reference: Anion exchanger 1 (band 3) is required to prevent erythrocyte membrane surface loss but not to form the membrane skeleton. Cell. 1996 Sep 20; 86(6):917-27.
journal title abbreviation: Cell
publication date: 1996-09-20T00:00:00
year: 1996
type: Academic Article
type: Article
type: Document
type: Information Resource

Oral magnesium pidolate: effects of long-term administration in patients with sickle cell disease.
PubMed Identifier: 10691856
author list: De Franceschi L, Bachir D, Galacteros F, Tchernia G, Cynober T, Neuberg D, Beuzard Y, Brugnara C
published in: British journal of haematology
information resource reference: Oral magnesium pidolate: effects of long-term administration in patients with sickle cell disease. Br J Haematol. 2000 Feb; 108(2):284-9.
journal title abbreviation: Br J Haematol
publication date: 2000-02-01T00:00:00
year: 2000
type: Academic Article
type: Article
type: Document
type: Information Resource

Evidence for a protective role of the Gardos channel against hemolysis in murine spherocytosis.
PubMed Identifier: 15855279
author list: De Franceschi L, Rivera A, Fleming MD, Honczarenko M, Peters LL, Gascard P, Mohandas N, Brugnara C
published in: Blood
information resource reference: Evidence for a protective role of the Gardos channel against hemolysis in murine spherocytosis. Blood. 2005 Aug 15; 106(4):1454-9.
journal title abbreviation: Blood
publication date: 2005-04-26T00:00:00
year: 2005
type: Academic Article
type: Article
type: Document
type: Information Resource

Therapeutic strategies for prevention of sickle cell dehydration.
PubMed Identifier: 11358364
author list: Brugnara C
published in: Blood cells, molecules & diseases
information resource reference: Therapeutic strategies for prevention of sickle cell dehydration. Blood Cells Mol Dis. 2001 Jan-Feb; 27(1):71-80.
journal title abbreviation: Blood Cells Mol Dis
publication date: 2001-01-01T00:00:00
year: 2001
type: Academic Article
type: Article
type: Document
type: Information Resource

Hydroxyurea and erythropoietin therapy in sickle cell anemia.
PubMed Identifier: 1379376
author list: Goldberg MA, Brugnara C, Dover GJ, Schapira L, Lacroix L, Bunn HF
published in: Seminars in oncology
information resource reference: Hydroxyurea and erythropoietin therapy in sickle cell anemia. Semin Oncol. 1992 Jun; 19(3 Suppl 9):74-81.
journal title abbreviation: Semin Oncol
publication date: 1992-06-01T00:00:00
year: 1992
type: Academic Article
type: Article
type: Document
type: Information Resource

Treatment with NS3623, a novel Cl-conductance blocker, ameliorates erythrocyte dehydration in transgenic SAD mice: a possible new therapeutic approach for sickle cell disease.
PubMed Identifier: 11222393
author list: Bennekou P, de Franceschi L, Pedersen O, Lian L, Asakura T, Evans G, Brugnara C, Christophersen P
published in: Blood
information resource reference: Treatment with NS3623, a novel Cl-conductance blocker, ameliorates erythrocyte dehydration in transgenic SAD mice: a possible new therapeutic approach for sickle cell disease. Blood. 2001 Mar 01; 97(5):1451-7.
journal title abbreviation: Blood
publication date: 2001-03-01T00:00:00
year: 2001
type: Academic Article
type: Article
type: Document
type: Information Resource

Erythrocyte-active agents and treatment of sickle cell disease.
PubMed Identifier: 11605167
author list: Brugnara C, De Franceschi L, Beuzard Y
published in: Seminars in hematology
information resource reference: Erythrocyte-active agents and treatment of sickle cell disease. Semin Hematol. 2001 Oct; 38(4):324-32.
journal title abbreviation: Semin Hematol
publication date: 2001-10-01T00:00:00
year: 2001
type: Academic Article
type: Article
type: Document
type: Information Resource

Full-disclosure in industry-sponsored laboratory medicine research studies: statement by the Consortium of Laboratory Medicine Journal Editors.
PubMed Identifier: 21174565
author list: Rifai N, Plebani M, Wu A, Brugnara C, Delvin E, Lamb EJ, Ness PM, Wick MR, Berg JP
published in: Scandinavian journal of clinical and laboratory investigation
information resource reference: Full-disclosure in industry-sponsored laboratory medicine research studies: statement by the Consortium of Laboratory Medicine Journal Editors. Scand J Clin Lab Invest. 2011 May; 71(3):177-8.
journal title abbreviation: Scand J Clin Lab Invest
publication date: 2010-12-21T00:00:00
year: 2010
type: Academic Article
type: Article
type: Document
type: Information Resource

Functional characterization and modified rescue of novel AE1 mutation R730C associated with overhydrated cation leak stomatocytosis.
PubMed Identifier: 21209359
author list: Stewart AK, Kedar PS, Shmukler BE, Vandorpe DH, Hsu A, Glader B, Rivera A, Brugnara C, Alper SL
published in: American journal of physiology. Cell physiology
information resource reference: Functional characterization and modified rescue of novel AE1 mutation R730C associated with overhydrated cation leak stomatocytosis. Am J Physiol Cell Physiol. 2011 May; 300(5):C1034-46.
journal title abbreviation: Am J Physiol Cell Physiol
publication date: 2011-01-05T00:00:00
year: 2011
type: Academic Article
type: Article
type: Document
type: Information Resource

An appeal to medical journal editors: the need for a full description of laboratory methods and specimen handling in clinical study reports.
PubMed Identifier: 22261017
author list: Rifai N, Annesley TM, Berg JP, Brugnara C, Delvin E, Lamb EJ, Ness PM, Plebani M, Wick MR, Wu A, Delanghe J
published in: Clinica chimica acta; international journal of clinical chemistry
information resource reference: An appeal to medical journal editors: the need for a full description of laboratory methods and specimen handling in clinical study reports. Clin Chim Acta. 2012 Apr 11; 413(7-8):653-5.
journal title abbreviation: Clin Chim Acta
publication date: 2012-01-13T00:00:00
year: 2012
type: Academic Article
type: Article
type: Document
type: Information Resource

Hydroxyurea and sickle cell disease: a chance for every patient.
PubMed Identifier: 12672739
author list: Weiner DL, Brugnara C
published in: JAMA
information resource reference: Hydroxyurea and sickle cell disease: a chance for every patient. JAMA. 2003 Apr 02; 289(13):1692-4.
journal title abbreviation: JAMA
publication date: 2003-04-02T00:00:00
year: 2003
type: Academic Article
type: Article
type: Document
type: Information Resource

Anemia in hemodialysis patients: variables affecting this outcome predictor.
PubMed Identifier: 9402095
author list: Madore F, Lowrie EG, Brugnara C, Lew NL, Lazarus JM, Bridges K, Owen WF
published in: Journal of the American Society of Nephrology : JASN
information resource reference: Anemia in hemodialysis patients: variables affecting this outcome predictor. J Am Soc Nephrol. 1997 Dec; 8(12):1921-9.
journal title abbreviation: J Am Soc Nephrol
publication date: 1997-12-01T00:00:00
year: 1997
type: Academic Article
type: Article
type: Document
type: Information Resource

A multiparameter analysis of sickle erythrocytes in patients undergoing hydroxyurea therapy.
PubMed Identifier: 8977264
author list: Bridges KR, Barabino GD, Brugnara C, Cho MR, Christoph GW, Dover G, Ewenstein BM, Golan DE, Guttmann CR, Hofrichter J, Mulkern RV, Zhang B, Eaton WA
published in: Blood
information resource reference: A multiparameter analysis of sickle erythrocytes in patients undergoing hydroxyurea therapy. Blood. 1996 Dec 15; 88(12):4701-10.
journal title abbreviation: Blood
publication date: 1996-12-15T00:00:00
year: 1996
type: Academic Article
type: Article
type: Document
type: Information Resource

Mild spherocytosis and altered red cell ion transport in protein 4. 2-null mice.
PubMed Identifier: 10359562
author list: Peters LL, Jindel HK, Gwynn B, Korsgren C, John KM, Lux SE, Mohandas N, Cohen CM, Cho MR, Golan DE, Brugnara C
published in: The Journal of clinical investigation
information resource reference: Mild spherocytosis and altered red cell ion transport in protein 4. 2-null mice. J Clin Invest. 1999 Jun; 103(11):1527-37.
journal title abbreviation: J Clin Invest
publication date: 1999-06-01T00:00:00
year: 1999
type: Academic Article
type: Article
type: Document
type: Information Resource

E2F4 is essential for normal erythrocyte maturation and neonatal viability.
PubMed Identifier: 10983976
author list: Humbert PO, Rogers C, Ganiatsas S, Landsberg RL, Trimarchi JM, Dandapani S, Brugnara C, Erdman S, Schrenzel M, Bronson RT, Lees JA
published in: Molecular cell
information resource reference: E2F4 is essential for normal erythrocyte maturation and neonatal viability. Mol Cell. 2000 Aug; 6(2):281-91.
journal title abbreviation: Mol Cell
publication date: 2000-08-01T00:00:00
year: 2000
type: Academic Article
type: Article
type: Document
type: Information Resource

Erythrocyte dehydration in pathophysiology and treatment of sickle cell disease.
PubMed Identifier: 9371983
author list: Brugnara C
published in: Current opinion in hematology
information resource reference: Erythrocyte dehydration in pathophysiology and treatment of sickle cell disease. Curr Opin Hematol. 1995 Mar; 2(2):132-8.
journal title abbreviation: Curr Opin Hematol
publication date: 1995-03-01T00:00:00
year: 1995
type: Academic Article
type: Article
type: Document
type: Information Resource

Autosomal dominant distal renal tubular acidosis is associated in three families with heterozygosity for the R589H mutation in the AE1 (band 3) Cl-/HCO3- exchanger.
PubMed Identifier: 9497368
author list: Jarolim P, Shayakul C, Prabakaran D, Jiang L, Stuart-Tilley A, Rubin HL, Simova S, Zavadil J, Herrin JT, Brouillette J, Somers MJ, Seemanova E, Brugnara C, Guay-Woodford LM, Alper SL
published in: The Journal of biological chemistry
information resource reference: Autosomal dominant distal renal tubular acidosis is associated in three families with heterozygosity for the R589H mutation in the AE1 (band 3) Cl-/HCO3- exchanger. J Biol Chem. 1998 Mar 13; 273(11):6380-8.
journal title abbreviation: J Biol Chem
publication date: 1998-03-13T00:00:00
year: 1998
type: Academic Article
type: Article
type: Document
type: Information Resource

Use of reticulocyte cellular indices in the diagnosis and treatment of hematological disorders.
PubMed Identifier: 9594357
author list: Brugnara C
published in: International journal of clinical & laboratory research
information resource reference: Use of reticulocyte cellular indices in the diagnosis and treatment of hematological disorders. Int J Clin Lab Res. 1998; 28(1):1-11.
journal title abbreviation: Int J Clin Lab Res
publication date: 1998-01-01T00:00:00
year: 1998
type: Academic Article
type: Article
type: Document
type: Information Resource

The effect of hemoglobin A and S on the volume- and pH-dependence of K-Cl cotransport in human erythrocyte ghosts.
PubMed Identifier: 9929375
author list: Vitoux D, Beuzard Y, Brugnara C
published in: The Journal of membrane biology
information resource reference: The effect of hemoglobin A and S on the volume- and pH-dependence of K-Cl cotransport in human erythrocyte ghosts. J Membr Biol. 1999 Feb 01; 167(3):233-40.
journal title abbreviation: J Membr Biol
publication date: 1999-02-01T00:00:00
year: 1999
type: Academic Article
type: Article
type: Document
type: Information Resource

Serine/threonine protein phosphatases and regulation of K-Cl cotransport in human erythrocytes.
PubMed Identifier: 10564085
author list: Bize I, Güvenç B, Robb A, Buchbinder G, Brugnara C
published in: The American journal of physiology
information resource reference: Serine/threonine protein phosphatases and regulation of K-Cl cotransport in human erythrocytes. Am J Physiol. 1999 11; 277(5):C926-36.
journal title abbreviation: Am J Physiol
publication date: 1999-11-01T00:00:00
year: 1999
type: Academic Article
type: Article
type: Document
type: Information Resource

Quantitative trait loci for baseline white blood cell count, platelet count, and mean platelet volume.
PubMed Identifier: 16261417
author list: Peters LL, Zhang W, Lambert AJ, Brugnara C, Churchill GA, Platt OS
published in: Mammalian genome : official journal of the International Mammalian Genome Society
information resource reference: Quantitative trait loci for baseline white blood cell count, platelet count, and mean platelet volume. Mamm Genome. 2005 Oct; 16(10):749-63.
journal title abbreviation: Mamm Genome
publication date: 2005-10-29T00:00:00
year: 2005
type: Academic Article
type: Article
type: Document
type: Information Resource

Acid pH induces formation of dense cells in sickle erythrocytes.
PubMed Identifier: 2752126
author list: Brugnara C, Van Ha T, Tosteson DC
published in: Blood
information resource reference: Acid pH induces formation of dense cells in sickle erythrocytes. Blood. 1989 Jul; 74(1):487-95.
journal title abbreviation: Blood
publication date: 1989-07-01T00:00:00
year: 1989
type: Academic Article
type: Article
type: Document
type: Information Resource

5-hydroxymethyl-2-furfural modifies intracellular sickle haemoglobin and inhibits sickling of red blood cells.
PubMed Identifier: 15686467
author list: Abdulmalik O, Safo MK, Chen Q, Yang J, Brugnara C, Ohene-Frempong K, Abraham DJ, Asakura T
published in: British journal of haematology
information resource reference: 5-hydroxymethyl-2-furfural modifies intracellular sickle haemoglobin and inhibits sickling of red blood cells. Br J Haematol. 2005 Feb; 128(4):552-61.
journal title abbreviation: Br J Haematol
publication date: 2005-02-01T00:00:00
year: 2005
type: Academic Article
type: Article
type: Document
type: Information Resource

Loss-of-function and gain-of-function phenotypes of stomatocytosis mutant RhAG F65S.
PubMed Identifier: 21849667
author list: Stewart AK, Shmukler BE, Vandorpe DH, Rivera A, Heneghan JF, Li X, Hsu A, Karpatkin M, O'Neill AF, Bauer DE, Heeney MM, John K, Kuypers FA, Gallagher PG, Lux SE, Brugnara C, Westhoff CM, Alper SL
published in: American journal of physiology. Cell physiology
information resource reference: Loss-of-function and gain-of-function phenotypes of stomatocytosis mutant RhAG F65S. Am J Physiol Cell Physiol. 2011 Dec; 301(6):C1325-43.
journal title abbreviation: Am J Physiol Cell Physiol
publication date: 2011-08-17T00:00:00
year: 2011
type: Academic Article
type: Article
type: Document
type: Information Resource

Screening healthy infants for iron deficiency using reticulocyte hemoglobin content.
PubMed Identifier: 16118382
author list: Ullrich C, Wu A, Armsby C, Rieber S, Wingerter S, Brugnara C, Shapiro D, Bernstein H
published in: JAMA
information resource reference: Screening healthy infants for iron deficiency using reticulocyte hemoglobin content. JAMA. 2005 Aug 24; 294(8):924-30.
journal title abbreviation: JAMA
publication date: 2005-08-24T00:00:00
year: 2005
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 986199
type: Authorship
author rank in publication: 8
linked author: Brugnara, Carlo
linked information resource: Genome-wide association study of erythrocyte density in sickle cell disease patients.

Genome-wide association study of erythrocyte density in sickle cell disease patients.
PubMed Identifier: 28552477
author list: Ilboudo Y, Bartolucci P, Rivera A, Sedzro JC, Beaudoin M, Trudel M, Alper SL, Brugnara C, Galactéros F, Lettre G
published in: Blood cells, molecules & diseases
information resource reference: Genome-wide association study of erythrocyte density in sickle cell disease patients. Blood Cells Mol Dis. 2017 06; 65:60-65.
journal title abbreviation: Blood Cells Mol Dis
publication date: 2017-05-13T00:00:00
year: 2017
type: Academic Article
type: Article
type: Document
type: Information Resource

Quantitative trait loci for baseline erythroid traits.
PubMed Identifier: 16596451
author list: Peters LL, Lambert AJ, Zhang W, Churchill GA, Brugnara C, Platt OS
published in: Mammalian genome : official journal of the International Mammalian Genome Society
information resource reference: Quantitative trait loci for baseline erythroid traits. Mamm Genome. 2006 Apr; 17(4):298-309.
journal title abbreviation: Mamm Genome
publication date: 2006-04-04T00:00:00
year: 2006
type: Academic Article
type: Article
type: Document
type: Information Resource

Positional cloning of the zebrafish sauternes gene: a model for congenital sideroblastic anaemia.
PubMed Identifier: 9806542
author list: Brownlie A, Donovan A, Pratt SJ, Paw BH, Oates AC, Brugnara C, Witkowska HE, Sassa S, Zon LI
published in: Nature genetics
information resource reference: Positional cloning of the zebrafish sauternes gene: a model for congenital sideroblastic anaemia. Nat Genet. 1998 Nov; 20(3):244-50.
journal title abbreviation: Nat Genet
publication date: 1998-11-01T00:00:00
year: 1998
type: Academic Article
type: Article
type: Document
type: Information Resource

Positional cloning of zebrafish ferroportin1 identifies a conserved vertebrate iron exporter.
PubMed Identifier: 10693807
author list: Donovan A, Brownlie A, Zhou Y, Shepard J, Pratt SJ, Moynihan J, Paw BH, Drejer A, Barut B, Zapata A, Law TC, Brugnara C, Lux SE, Pinkus GS, Pinkus JL, Kingsley PD, Palis J, Fleming MD, Andrews NC, Zon LI
published in: Nature
information resource reference: Positional cloning of zebrafish ferroportin1 identifies a conserved vertebrate iron exporter. Nature. 2000 Feb 17; 403(6771):776-81.
journal title abbreviation: Nature
publication date: 2000-02-17T00:00:00
year: 2000
type: Academic Article
type: Article
type: Document
type: Information Resource

Hemolytic anemia induced by ribavirin therapy in patients with chronic hepatitis C virus infection: role of membrane oxidative damage.
PubMed Identifier: 10733558
author list: De Franceschi L, Fattovich G, Turrini F, Ayi K, Brugnara C, Manzato F, Noventa F, Stanzial AM, Solero P, Corrocher R
published in: Hepatology (Baltimore, Md.)
information resource reference: Hemolytic anemia induced by ribavirin therapy in patients with chronic hepatitis C virus infection: role of membrane oxidative damage. Hepatology. 2000 Apr; 31(4):997-1004.
journal title abbreviation: Hepatology
publication date: 2000-04-01T00:00:00
year: 2000
type: Academic Article
type: Article
type: Document
type: Information Resource

Effect of irradiation on red cell cation content and transport.
PubMed Identifier: 1557807
author list: Brugnara C, Churchill WH
published in: Transfusion
information resource reference: Effect of irradiation on red cell cation content and transport. Transfusion. 1992 Mar-Apr; 32(3):246-52.
journal title abbreviation: Transfusion
publication date: 1992-03-01T00:00:00
year: 1992
type: Academic Article
type: Article
type: Document
type: Information Resource

Hypoxia activates a Ca2+-permeable cation conductance sensitive to carbon monoxide and to GsMTx-4 in human and mouse sickle erythrocytes.
PubMed Identifier: 20090940
author list: Vandorpe DH, Xu C, Shmukler BE, Otterbein LE, Trudel M, Sachs F, Gottlieb PA, Brugnara C, Alper SL
published in: PloS one
information resource reference: Hypoxia activates a Ca2+-permeable cation conductance sensitive to carbon monoxide and to GsMTx-4 in human and mouse sickle erythrocytes. PLoS One. 2010 Jan 15; 5(1):e8732.
journal title abbreviation: PLoS One
publication date: 2010-01-15T00:00:00
year: 2010
type: Academic Article
type: Article
type: Document
type: Information Resource

Erythrocyte density in sickle cell syndromes is associated with specific clinical manifestations and hemolysis.
PubMed Identifier: 22919030
author list: Bartolucci P, Brugnara C, Teixeira-Pinto A, Pissard S, Moradkhani K, Jouault H, Galacteros F
published in: Blood
information resource reference: Erythrocyte density in sickle cell syndromes is associated with specific clinical manifestations and hemolysis. Blood. 2012 Oct 11; 120(15):3136-41.
journal title abbreviation: Blood
publication date: 2012-08-23T00:00:00
year: 2012
type: Academic Article
type: Article
type: Document
type: Information Resource

An immunoassay for human serum hepcidin at last: Ganz klar?
PubMed Identifier: 18988874
author list: Brugnara C
published in: Blood
information resource reference: An immunoassay for human serum hepcidin at last: Ganz klar? Blood. 2008 Nov 15; 112(10):3922-3.
journal title abbreviation: Blood
publication date: 2008-11-15T00:00:00
year: 2008
type: Academic Article
type: Article
type: Document
type: Information Resource

Sequence variation at multiple loci influences red cell hemoglobin concentration.
PubMed Identifier: 20833975
author list: Peters LL, Shavit JA, Lambert AJ, Tsaih SW, Li Q, Su Z, Leduc MS, Paigen B, Churchill GA, Ginsburg D, Brugnara C
published in: Blood
information resource reference: Sequence variation at multiple loci influences red cell hemoglobin concentration. Blood. 2010 Dec 16; 116(25):e139-49.
journal title abbreviation: Blood
publication date: 2010-09-10T00:00:00
year: 2010
type: Academic Article
type: Article
type: Document
type: Information Resource

Role of chloride in potassium transport through a K-Cl cotransport system in human red blood cells.
PubMed Identifier: 2719101
author list: Brugnara C, Van Ha T, Tosteson DC
published in: The American journal of physiology
information resource reference: Role of chloride in potassium transport through a K-Cl cotransport system in human red blood cells. Am J Physiol. 1989 May; 256(5 Pt 1):C994-1003.
journal title abbreviation: Am J Physiol
publication date: 1989-05-01T00:00:00
year: 1989
type: Academic Article
type: Article
type: Document
type: Information Resource

Full-disclosure in industry-sponsored laboratory medicine research studies: statement by the Consortium of Laboratory Medicine Journal Editors.
PubMed Identifier: 21159312
author list: Rifai N, Plebani M, Wu AH, Delanghe J, Brugnara C, Delvin E, Lamb EJ, Ness PM, Wick MR, Berg JP
published in: Clinica chimica acta; international journal of clinical chemistry
information resource reference: Full-disclosure in industry-sponsored laboratory medicine research studies: statement by the Consortium of Laboratory Medicine Journal Editors. Clin Chim Acta. 2011 Mar 18; 412(7-8):491-2.
journal title abbreviation: Clin Chim Acta
publication date: 2010-12-14T00:00:00
year: 2010
type: Academic Article
type: Article
type: Document
type: Information Resource

Daily multivitamins with iron to prevent anemia in high-risk infants: a randomized clinical trial.
PubMed Identifier: 15231912
author list: Geltman PL, Meyers AF, Mehta SD, Brugnara C, Villon I, Wu YA, Bauchner H
published in: Pediatrics
information resource reference: Daily multivitamins with iron to prevent anemia in high-risk infants: a randomized clinical trial. Pediatrics. 2004 Jul; 114(1):86-93.
journal title abbreviation: Pediatrics
publication date: 2004-07-01T00:00:00
year: 2004
type: Academic Article
type: Article
type: Document
type: Information Resource

Mutations of conserved arginines in the membrane domain of erythroid band 3 lead to a decrease in membrane-associated band 3 and to the phenotype of hereditary spherocytosis.
PubMed Identifier: 7530501
author list: Jarolim P, Rubin HL, Brabec V, Chrobak L, Zolotarev AS, Alper SL, Brugnara C, Wichterle H, Palek J
published in: Blood
information resource reference: Mutations of conserved arginines in the membrane domain of erythroid band 3 lead to a decrease in membrane-associated band 3 and to the phenotype of hereditary spherocytosis. Blood. 1995 Feb 01; 85(3):634-40.
journal title abbreviation: Blood
publication date: 1995-02-01T00:00:00
year: 1995
type: Academic Article
type: Article
type: Document
type: Information Resource

Oxidative damage and erythrocyte membrane transport abnormalities in thalassemias.
PubMed Identifier: 8018927
author list: Olivieri O, De Franceschi L, Capellini MD, Girelli D, Corrocher R, Brugnara C
published in: Blood
information resource reference: Oxidative damage and erythrocyte membrane transport abnormalities in thalassemias. Blood. 1994 Jul 01; 84(1):315-20.
journal title abbreviation: Blood
publication date: 1994-07-01T00:00:00
year: 1994
type: Academic Article
type: Article
type: Document
type: Information Resource

Sulfhydryl oxidation and activation of red cell K(+)-Cl- cotransport in the transgenic SAD mouse.
PubMed Identifier: 7485459
author list: De Franceschi L, Beuzard Y, Brugnara C
published in: The American journal of physiology
information resource reference: Sulfhydryl oxidation and activation of red cell K(+)-Cl- cotransport in the transgenic SAD mouse. Am J Physiol. 1995 Oct; 269(4 Pt 1):C899-906.
journal title abbreviation: Am J Physiol
publication date: 1995-10-01T00:00:00
year: 1995
type: Academic Article
type: Article
type: Document
type: Information Resource

The effect of intravenous iron on the reticulocyte response to recombinant human erythropoietin.
PubMed Identifier: 9266922
author list: Major A, Mathez-Loic F, Rohling R, Gautschi K, Brugnara C
published in: British journal of haematology
information resource reference: The effect of intravenous iron on the reticulocyte response to recombinant human erythropoietin. Br J Haematol. 1997 Aug; 98(2):292-4.
journal title abbreviation: Br J Haematol
publication date: 1997-08-01T00:00:00
year: 1997
type: Academic Article
type: Article
type: Document
type: Information Resource

Low concentrations of nitric oxide increase oxygen affinity of sickle erythrocytes in vitro and in vivo.
PubMed Identifier: 9276736
author list: Head CA, Brugnara C, Martinez-Ruiz R, Kacmarek RM, Bridges KR, Kuter D, Bloch KD, Zapol WM
published in: The Journal of clinical investigation
information resource reference: Low concentrations of nitric oxide increase oxygen affinity of sickle erythrocytes in vitro and in vivo. J Clin Invest. 1997 Sep 01; 100(5):1193-8.
journal title abbreviation: J Clin Invest
publication date: 1997-09-01T00:00:00
year: 1997
type: Academic Article
type: Article
type: Document
type: Information Resource

Effect of metabolic depletion on the furosemide-sensitive Na and K fluxes in human red cells.
PubMed Identifier: 2993628
author list: Dagher G, Brugnara C, Canessa M
published in: The Journal of membrane biology
information resource reference: Effect of metabolic depletion on the furosemide-sensitive Na and K fluxes in human red cells. J Membr Biol. 1985; 86(2):145-55.
journal title abbreviation: J Membr Biol
publication date: 1985-01-01T00:00:00
year: 1985
type: Academic Article
type: Article
type: Document
type: Information Resource

Full-disclosure in industry-sponsored laboratory medicine research studies: statement by the Consortium of Laboratory Medicine Journal Editors.
PubMed Identifier: 21155691
author list: Rifai N, Plebani M, Wu A, Brugnara C, Delvin E, Lamb EJ, Ness PM, Wick MR, Berg JP
published in: Clinical chemistry and laboratory medicine
information resource reference: Full-disclosure in industry-sponsored laboratory medicine research studies: statement by the Consortium of Laboratory Medicine Journal Editors. Clin Chem Lab Med. 2011 Jan; 49(1):3-4.
journal title abbreviation: Clin Chem Lab Med
publication date: 2010-12-15T00:00:00
year: 2010
type: Academic Article
type: Article
type: Document
type: Information Resource

An appeal to medical journal editors: the need for a full description of laboratory methods and specimen handling in clinical study reports.
PubMed Identifier: 22505546
author list: Rifai N, Annesley TM, Berg JP, Brugnara C, Delvin E, Lamb EJ, Ness PM, Plebani M, Wick MR, Wu A, Delanghe J
published in: Clinical chemistry and laboratory medicine
information resource reference: An appeal to medical journal editors: the need for a full description of laboratory methods and specimen handling in clinical study reports. Clin Chem Lab Med. 2012 Mar; 50(3):411-3.
journal title abbreviation: Clin Chem Lab Med
publication date: 2012-03-01T00:00:00
year: 2012
type: Academic Article
type: Article
type: Document
type: Information Resource

Ca2+-activated K+ efflux limits complement-mediated lysis of human erythrocytes.
PubMed Identifier: 2708520
author list: Halperin JA, Brugnara C, Nicholson-Weller A
published in: The Journal of clinical investigation
information resource reference: Ca2+-activated K+ efflux limits complement-mediated lysis of human erythrocytes. J Clin Invest. 1989 May; 83(5):1466-71.
journal title abbreviation: J Clin Invest
publication date: 1989-05-01T00:00:00
year: 1989
type: Academic Article
type: Article
type: Document
type: Information Resource

Pharmacological inhibition of calpain-1 prevents red cell dehydration and reduces Gardos channel activity in a mouse model of sickle cell disease.
PubMed Identifier: 23085996
author list: De Franceschi L, Franco RS, Bertoldi M, Brugnara C, Matté A, Siciliano A, Wieschhaus AJ, Chishti AH, Joiner CH
published in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology
information resource reference: Pharmacological inhibition of calpain-1 prevents red cell dehydration and reduces Gardos channel activity in a mouse model of sickle cell disease. FASEB J. 2013 Feb; 27(2):750-9.
journal title abbreviation: FASEB J
publication date: 2012-10-19T00:00:00
year: 2012
type: Academic Article
type: Article
type: Document
type: Information Resource

Elevation of red cell sodium-lithium countertransport in hyperlipidemias.
PubMed Identifier: 3968981
author list: Corrocher R, Steinmayr M, Ruzzenente O, Brugnara C, Bertinato L, Mazzi M, Furri C, Bonfanti F, De Sandre G
published in: Life sciences
information resource reference: Elevation of red cell sodium-lithium countertransport in hyperlipidemias. Life Sci. 1985 Feb 18; 36(7):649-55.
journal title abbreviation: Life Sci
publication date: 1985-02-18T00:00:00
year: 1985
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1008522
type: Authorship
author rank in publication: 2
linked author: Brugnara, Carlo
linked information resource: Automated cell counts on CSF samples: A multicenter performance evaluation of the GloCyte system.

Automated cell counts on CSF samples: A multicenter performance evaluation of the GloCyte system.
PubMed Identifier: 28880455
author list: Hod EA, Brugnara C, Pilichowska M, Sandhaus LM, Luu HS, Forest SK, Netterwald JC, Reynafarje GM, Kratz A
published in: International journal of laboratory hematology
information resource reference: Automated cell counts on CSF samples: A multicenter performance evaluation of the GloCyte system. Int J Lab Hematol. 2018 Feb; 40(1):56-65.
journal title abbreviation: Int J Lab Hematol
publication date: 2017-09-07T00:00:00
year: 2017
type: Academic Article
type: Article
type: Document
type: Information Resource

Plasminogen activator inhibitor-1: defining characteristics in the cerebrospinal fluid of newborns.
PubMed Identifier: 10891836
author list: Hansen AR, Lapp C, Brugnara C
published in: The Journal of pediatrics
information resource reference: Plasminogen activator inhibitor-1: defining characteristics in the cerebrospinal fluid of newborns. J Pediatr. 2000 Jul; 137(1):132-4.
journal title abbreviation: J Pediatr
publication date: 2000-07-01T00:00:00
year: 2000
type: Academic Article
type: Article
type: Document
type: Information Resource

Use of a preoperative bleeding questionnaire in pediatric patients who undergo adenotonsillectomy.
PubMed Identifier: 18922342
author list: Licameli GR, Jones DT, Santosuosso J, Lapp C, Brugnara C, Kenna MA
published in: Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery
information resource reference: Use of a preoperative bleeding questionnaire in pediatric patients who undergo adenotonsillectomy. Otolaryngol Head Neck Surg. 2008 Oct; 139(4):546-550.
journal title abbreviation: Otolaryngol Head Neck Surg
publication date: 2008-10-01T00:00:00
year: 2008
type: Academic Article
type: Article
type: Document
type: Information Resource

PTPepsilon has a critical role in signaling transduction pathways and phosphoprotein network topology in red cells.
PubMed Identifier: 18924107
author list: De Franceschi L, Biondani A, Carta F, Turrini F, Laudanna C, Deana R, Brunati AM, Turretta L, Iolascon A, Perrotta S, Elson A, Bulato C, Brugnara C
published in: Proteomics
information resource reference: PTPepsilon has a critical role in signaling transduction pathways and phosphoprotein network topology in red cells. Proteomics. 2008 Nov; 8(22):4695-708.
journal title abbreviation: Proteomics
publication date: 2008-11-01T00:00:00
year: 2008
type: Academic Article
type: Article
type: Document
type: Information Resource

Voltage-activated cation transport in human erythrocytes.
PubMed Identifier: 2596592
author list: Halperin JA, Brugnara C, Tosteson MT, Van Ha T, Tosteson DC
published in: The American journal of physiology
information resource reference: Voltage-activated cation transport in human erythrocytes. Am J Physiol. 1989 Nov; 257(5 Pt 1):C986-96.
journal title abbreviation: Am J Physiol
publication date: 1989-11-01T00:00:00
year: 1989
type: Academic Article
type: Article
type: Document
type: Information Resource

Ion content and transport and the regulation of volume in sickle cells.
PubMed Identifier: 2672974
author list: Brugnara C, Bunn HF, Tosteson DC
published in: Annals of the New York Academy of Sciences
information resource reference: Ion content and transport and the regulation of volume in sickle cells. Ann N Y Acad Sci. 1989; 565:96-103.
journal title abbreviation: Ann N Y Acad Sci
publication date: 1989-01-01T00:00:00
year: 1989
type: Academic Article
type: Article
type: Document
type: Information Resource

In vitro genetic analysis of an erythrocyte determinant of malaria infection.
PubMed Identifier: 20958212
author list: Bei AK, Brugnara C, Duraisingh MT
published in: The Journal of infectious diseases
information resource reference: In vitro genetic analysis of an erythrocyte determinant of malaria infection. J Infect Dis. 2010 Dec 01; 202(11):1722-7.
journal title abbreviation: J Infect Dis
publication date: 2010-10-19T00:00:00
year: 2010
type: Academic Article
type: Article
type: Document
type: Information Resource

Characterization of adult alpha- and beta-globin genes in the zebrafish.
PubMed Identifier: 9002973
author list: Chan FY, Robinson J, Brownlie A, Shivdasani RA, Donovan A, Brugnara C, Kim J, Lau BC, Witkowska HE, Zon LI
published in: Blood
information resource reference: Characterization of adult alpha- and beta-globin genes in the zebrafish. Blood. 1997 Jan 15; 89(2):688-700.
journal title abbreviation: Blood
publication date: 1997-01-15T00:00:00
year: 1997
type: Academic Article
type: Article
type: Document
type: Information Resource

Oxygen gas-filled microparticles provide intravenous oxygen delivery.
PubMed Identifier: 22745438
author list: Kheir JN, Scharp LA, Borden MA, Swanson EJ, Loxley A, Reese JH, Black KJ, Velazquez LA, Thomson LM, Walsh BK, Mullen KE, Graham DA, Lawlor MW, Brugnara C, Bell DC, McGowan FX
published in: Science translational medicine
information resource reference: Oxygen gas-filled microparticles provide intravenous oxygen delivery. Sci Transl Med. 2012 Jun 27; 4(140):140ra88.
journal title abbreviation: Sci Transl Med
publication date: 2012-06-27T00:00:00
year: 2012
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1015506
type: Authorship
author rank in publication: 6
linked author: Brugnara, Carlo
linked information resource: Revised prevalence estimate of possible Hereditary Xerocytosis as derived from a large U.S. Laboratory database.

Revised prevalence estimate of possible Hereditary Xerocytosis as derived from a large U.S. Laboratory database.
PubMed Identifier: 28971500
author list: Kaufman HW, Niles JK, Gallagher DR, Rivera A, Alper SL, Brugnara C, Snyder LM
published in: American journal of hematology
information resource reference: Revised prevalence estimate of possible Hereditary Xerocytosis as derived from a large U.S. Laboratory database. Am J Hematol. 2018 01; 93(1):E9-E12.
journal title abbreviation: Am J Hematol
publication date: 2017-11-23T00:00:00
year: 2017
type: Academic Article
type: Article
type: Document
type: Information Resource

Furosemide-sensitive Na and K fluxes in human red cells. Net uphill Na extrusion and equilibrium properties.
PubMed Identifier: 3950577
author list: Brugnara C, Canessa M, Cusi D, Tosteson DC
published in: The Journal of general physiology
information resource reference: Furosemide-sensitive Na and K fluxes in human red cells. Net uphill Na extrusion and equilibrium properties. J Gen Physiol. 1986 Jan; 87(1):91-112.
journal title abbreviation: J Gen Physiol
publication date: 1986-01-01T00:00:00
year: 1986
type: Academic Article
type: Article
type: Document
type: Information Resource

Membrane properties of erythrocytes in subjects undergoing multiple blood donations with or without recombinant erythropoietin.
PubMed Identifier: 8393334
author list: Brugnara C, Kruskall MS, Johnstone RM
published in: British journal of haematology
information resource reference: Membrane properties of erythrocytes in subjects undergoing multiple blood donations with or without recombinant erythropoietin. Br J Haematol. 1993 May; 84(1):118-30.
journal title abbreviation: Br J Haematol
publication date: 1993-05-01T00:00:00
year: 1993
type: Academic Article
type: Article
type: Document
type: Information Resource

Structure and genetic polymorphism of the mouse KCC1 gene.
PubMed Identifier: 11004507
author list: Shmukler BE, Brugnara C, Alper SL
published in: Biochimica et biophysica acta
information resource reference: Structure and genetic polymorphism of the mouse KCC1 gene. Biochim Biophys Acta. 2000 Jul 24; 1492(2-3):353-61.
journal title abbreviation: Biochim Biophys Acta
publication date: 2000-07-24T00:00:00
year: 2000
type: Academic Article
type: Article
type: Document
type: Information Resource

Reticulocyte parameters as potential discriminators of recombinant human erythropoietin abuse in elite athletes.
PubMed Identifier: 11071048
author list: Parisotto R, Gore CJ, Hahn AG, Ashenden MJ, Olds TS, Martin DT, Pyne DB, Gawthorn K, Brugnara C
published in: International journal of sports medicine
information resource reference: Reticulocyte parameters as potential discriminators of recombinant human erythropoietin abuse in elite athletes. Int J Sports Med. 2000 Oct; 21(7):471-9.
journal title abbreviation: Int J Sports Med
publication date: 2000-10-01T00:00:00
year: 2000
type: Academic Article
type: Article
type: Document
type: Information Resource

Thawing fresh frozen plasma in a microwave oven. A comparison with thawing in a 37 degrees C waterbath.
PubMed Identifier: 1546692
author list: Churchill WH, Schmidt B, Lindsey J, Greenberg M, Boudrow S, Brugnara C
published in: American journal of clinical pathology
information resource reference: Thawing fresh frozen plasma in a microwave oven. A comparison with thawing in a 37 degrees C waterbath. Am J Clin Pathol. 1992 Feb; 97(2):227-32.
journal title abbreviation: Am J Clin Pathol
publication date: 1992-02-01T00:00:00
year: 1992
type: Academic Article
type: Article
type: Document
type: Information Resource

Pathophysiological-based approaches to treatment of sickle cell disease.
PubMed Identifier: 12359829
author list: Steinberg MH, Brugnara C
published in: Annual review of medicine
information resource reference: Pathophysiological-based approaches to treatment of sickle cell disease. Annu Rev Med. 2003; 54:89-112.
journal title abbreviation: Annu Rev Med
publication date: 2001-12-03T00:00:00
year: 2001
type: Academic Article
type: Article
type: Document
type: Information Resource

Headpiece domain of dematin is required for the stability of the erythrocyte membrane.
PubMed Identifier: 12011427
author list: Khanna R, Chang SH, Andrabi S, Azam M, Kim A, Rivera A, Brugnara C, Low PS, Liu SC, Chishti AH
published in: Proceedings of the National Academy of Sciences of the United States of America
information resource reference: Headpiece domain of dematin is required for the stability of the erythrocyte membrane. Proc Natl Acad Sci U S A. 2002 May 14; 99(10):6637-42.
journal title abbreviation: Proc Natl Acad Sci U S A
publication date: 2002-05-14T00:00:00
year: 2002
type: Academic Article
type: Article
type: Document
type: Information Resource

Prevention of red cell dehydration: a possible new treatment for sickle cell disease.
PubMed Identifier: 12673842
author list: Mueller BU, Brugnara C
published in: Pediatric pathology & molecular medicine
information resource reference: Prevention of red cell dehydration: a possible new treatment for sickle cell disease. Pediatr Pathol Mol Med. 2001 Jan-Feb; 20(1):15-25.
journal title abbreviation: Pediatr Pathol Mol Med
publication date: 2001-01-01T00:00:00
year: 2001
type: Academic Article
type: Article
type: Document
type: Information Resource

Physiological roles of the intermediate conductance, Ca2+-activated potassium channel Kcnn4.
PubMed Identifier: 15347667
author list: Begenisich T, Nakamoto T, Ovitt CE, Nehrke K, Brugnara C, Alper SL, Melvin JE
published in: The Journal of biological chemistry
information resource reference: Physiological roles of the intermediate conductance, Ca2+-activated potassium channel Kcnn4. J Biol Chem. 2004 Nov 12; 279(46):47681-7.
journal title abbreviation: J Biol Chem
publication date: 2004-09-03T00:00:00
year: 2004
type: Academic Article
type: Article
type: Document
type: Information Resource

Suppression of Fas-FasL coexpression by erythropoietin mediates erythroblast expansion during the erythropoietic stress response in vivo.
PubMed Identifier: 16527892
author list: Liu Y, Pop R, Sadegh C, Brugnara C, Haase VH, Socolovsky M
published in: Blood
information resource reference: Suppression of Fas-FasL coexpression by erythropoietin mediates erythroblast expansion during the erythropoietic stress response in vivo. Blood. 2006 Jul 01; 108(1):123-33.
journal title abbreviation: Blood
publication date: 2006-03-09T00:00:00
year: 2006
type: Academic Article
type: Article
type: Document
type: Information Resource

Disruption of erythroid K-Cl cotransporters alters erythrocyte volume and partially rescues erythrocyte dehydration in SAD mice.
PubMed Identifier: 17510708
author list: Rust MB, Alper SL, Rudhard Y, Shmukler BE, Vicente R, Brugnara C, Trudel M, Jentsch TJ, Hübner CA
published in: The Journal of clinical investigation
information resource reference: Disruption of erythroid K-Cl cotransporters alters erythrocyte volume and partially rescues erythrocyte dehydration in SAD mice. J Clin Invest. 2007 Jun; 117(6):1708-17.
journal title abbreviation: J Clin Invest
publication date: 2007-05-17T00:00:00
year: 2007
type: Academic Article
type: Article
type: Document
type: Information Resource

Effect of complete protein 4.1R deficiency on ion transport properties of murine erythrocytes.
PubMed Identifier: 16774987
author list: Rivera A, De Franceschi L, Peters LL, Gascard P, Mohandas N, Brugnara C
published in: American journal of physiology. Cell physiology
information resource reference: Effect of complete protein 4.1R deficiency on ion transport properties of murine erythrocytes. Am J Physiol Cell Physiol. 2006 Nov; 291(5):C880-6.
journal title abbreviation: Am J Physiol Cell Physiol
publication date: 2006-06-14T00:00:00
year: 2006
type: Academic Article
type: Article
type: Document
type: Information Resource

Reticulocyte hemoglobin equivalent (Ret He) and assessment of iron-deficient states.
PubMed Identifier: 16999719
author list: Brugnara C, Schiller B, Moran J
published in: Clinical and laboratory haematology
information resource reference: Reticulocyte hemoglobin equivalent (Ret He) and assessment of iron-deficient states. Clin Lab Haematol. 2006 Oct; 28(5):303-8.
journal title abbreviation: Clin Lab Haematol
publication date: 2006-10-01T00:00:00
year: 2006
type: Academic Article
type: Article
type: Document
type: Information Resource

[Multiple renal arteries and arterial hypertension: a review of 337 renal arteriography cases].
PubMed Identifier: 7207818
author list: Bonfanti F, Corrocher R, Cherubini M, Brugnara C, Fugazzola C, Frasson F
published in: Minerva cardioangiologica
information resource reference: [Multiple renal arteries and arterial hypertension: a review of 337 renal arteriography cases]. Minerva Cardioangiol. 1980 May; 28(5):289-04.
journal title abbreviation: Minerva Cardioangiol
publication date: 1980-05-01T00:00:00
year: 1980
type: Academic Article
type: Article
type: Document
type: Information Resource

Modulation of Gardos channel activity by cytokines in sickle erythrocytes.
PubMed Identifier: 11756192
author list: Rivera A, Jarolim P, Brugnara C
published in: Blood
information resource reference: Modulation of Gardos channel activity by cytokines in sickle erythrocytes. Blood. 2002 Jan 01; 99(1):357-603.
journal title abbreviation: Blood
publication date: 2002-01-01T00:00:00
year: 2002
type: Academic Article
type: Article
type: Document
type: Information Resource

Membrane transport of Na and K and cell dehydration in sickle erythrocytes.
PubMed Identifier: 8440348
author list: Brugnara C
published in: Experientia
information resource reference: Membrane transport of Na and K and cell dehydration in sickle erythrocytes. Experientia. 1993 Feb 15; 49(2):100-9.
journal title abbreviation: Experientia
publication date: 1993-02-15T00:00:00
year: 1993
type: Academic Article
type: Article
type: Document
type: Information Resource

[Incidence of retinal and renal complications in arterial hypertension].
PubMed Identifier: 3714074
author list: Bonfanti F, Corrocher R, Bertinato L, Brugnara C, Nortilli R, De Sandre G
published in: Minerva cardioangiologica
information resource reference: [Incidence of retinal and renal complications in arterial hypertension]. Minerva Cardioangiol. 1986 Mar; 34(3):99-105.
journal title abbreviation: Minerva Cardioangiol
publication date: 1986-03-01T00:00:00
year: 1986
type: Academic Article
type: Article
type: Document
type: Information Resource

Protective effects of phosphodiesterase-4 (PDE-4) inhibition in the early phase of pulmonary arterial hypertension in transgenic sickle cell mice.
PubMed Identifier: 18245171
author list: De Franceschi L, Platt OS, Malpeli G, Janin A, Scarpa A, Leboeuf C, Beuzard Y, Payen E, Brugnara C
published in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology
information resource reference: Protective effects of phosphodiesterase-4 (PDE-4) inhibition in the early phase of pulmonary arterial hypertension in transgenic sickle cell mice. FASEB J. 2008 Jun; 22(6):1849-60.
journal title abbreviation: FASEB J
publication date: 2008-02-01T00:00:00
year: 2008
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1035127
type: Authorship
author rank in publication: 2
linked author: Brugnara, Carlo
linked information resource: Iron balance and iron supplementation for the female athlete: A practical approach.

Iron balance and iron supplementation for the female athlete: A practical approach.
PubMed Identifier: 29280410
author list: Pedlar CR, Brugnara C, Bruinvels G, Burden R
published in: European journal of sport science
information resource reference: Iron balance and iron supplementation for the female athlete: A practical approach. Eur J Sport Sci. 2018 Mar; 18(2):295-305.
journal title abbreviation: Eur J Sport Sci
publication date: 2017-12-27T00:00:00
year: 2017
type: Academic Article
type: Article
type: Document
type: Information Resource

Calpain-1 knockout reveals broad effects on erythrocyte deformability and physiology.
PubMed Identifier: 22870887
author list: Wieschhaus A, Khan A, Zaidi A, Rogalin H, Hanada T, Liu F, De Franceschi L, Brugnara C, Rivera A, Chishti AH
published in: The Biochemical journal
information resource reference: Calpain-1 knockout reveals broad effects on erythrocyte deformability and physiology. Biochem J. 2012 Nov 15; 448(1):141-52.
journal title abbreviation: Biochem J
publication date: 2012-11-15T00:00:00
year: 2012
type: Academic Article
type: Article
type: Document
type: Information Resource

Regulation of erythrocyte cation and water content in sickle cell anemia.
PubMed Identifier: 3961486
author list: Brugnara C, Bunn HF, Tosteson DC
published in: Science (New York, N.Y.)
information resource reference: Regulation of erythrocyte cation and water content in sickle cell anemia. Science. 1986 Apr 18; 232(4748):388-90.
journal title abbreviation: Science
publication date: 1986-04-18T00:00:00
year: 1986
type: Academic Article
type: Article
type: Document
type: Information Resource

Red blood cell regeneration induced by subcutaneous recombinant erythropoietin: iron-deficient erythropoiesis in iron-replete subjects.
PubMed Identifier: 8428002
author list: Brugnara C, Chambers LA, Malynn E, Goldberg MA, Kruskall MS
published in: Blood
information resource reference: Red blood cell regeneration induced by subcutaneous recombinant erythropoietin: iron-deficient erythropoiesis in iron-replete subjects. Blood. 1993 Feb 15; 81(4):956-64.
journal title abbreviation: Blood
publication date: 1993-02-15T00:00:00
year: 1993
type: Academic Article
type: Article
type: Document
type: Information Resource

Red cell indices in classification and treatment of anemias: from M.M. Wintrobes's original 1934 classification to the third millennium.
PubMed Identifier: 23449069
author list: Brugnara C, Mohandas N
published in: Current opinion in hematology
information resource reference: Red cell indices in classification and treatment of anemias: from M.M. Wintrobes's original 1934 classification to the third millennium. Curr Opin Hematol. 2013 May; 20(3):222-30.
journal title abbreviation: Curr Opin Hematol
publication date: 2013-05-01T00:00:00
year: 2013
type: Academic Article
type: Article
type: Document
type: Information Resource

Use of erythropoiesis stimulating agents and intravenous iron for cancer and treatment-related anaemia: the need for predictors and indicators of effectiveness has not abated.
PubMed Identifier: 18430192
author list: Katodritou E, Zervas K, Terpos E, Brugnara C
published in: British journal of haematology
information resource reference: Use of erythropoiesis stimulating agents and intravenous iron for cancer and treatment-related anaemia: the need for predictors and indicators of effectiveness has not abated. Br J Haematol. 2008 Jul; 142(1):3-10.
journal title abbreviation: Br J Haematol
publication date: 2008-04-22T00:00:00
year: 2008
type: Academic Article
type: Article
type: Document
type: Information Resource

Regulation of cation content and cell volume in hemoglobin erythrocytes from patients with homozygous hemoglobin C disease.
PubMed Identifier: 3998150
author list: Brugnara C, Kopin AS, Bunn HF, Tosteson DC
published in: The Journal of clinical investigation
information resource reference: Regulation of cation content and cell volume in hemoglobin erythrocytes from patients with homozygous hemoglobin C disease. J Clin Invest. 1985 May; 75(5):1608-17.
journal title abbreviation: J Clin Invest
publication date: 1985-05-01T00:00:00
year: 1985
type: Academic Article
type: Article
type: Document
type: Information Resource

Chemical crosslinking studies with the mouse Kcc1 K-Cl cotransporter.
PubMed Identifier: 19380103
author list: Casula S, Zolotarev AS, Stuart-Tilley AK, Wilhelm S, Shmukler BE, Brugnara C, Alper SL
published in: Blood cells, molecules & diseases
information resource reference: Chemical crosslinking studies with the mouse Kcc1 K-Cl cotransporter. Blood Cells Mol Dis. 2009 May-Jun; 42(3):233-40.
journal title abbreviation: Blood Cells Mol Dis
publication date: 2009-05-01T00:00:00
year: 2009
type: Academic Article
type: Article
type: Document
type: Information Resource

https://connects.catalyst.harvard.edu/Profiles/profile/977929
PubMed Identifier: 22296778
author list: Rifai N, Annesley TM, Berg JP, Brugnara C, Delvin E, Lamb EJ, Ness PM, Plebani M, Wick MR, Wu A, Delanghe J
published in: Annals of clinical biochemistry
information resource reference: An appeal to medical journal editors: the need for a full description of laboratory methods and specimen handling in clinical study reports. Statement by the Consortium of Laboratory Medicine Journal Editors. Ann Clin Biochem. 2012 Mar; 49(Pt 2):105-7.
journal title abbreviation: Ann Clin Biochem
publication date: 2012-02-01T00:00:00
year: 2012
type: Academic Article
type: Article
type: Document
type: Information Resource
label: An appeal to medical journal editors: the need for a full description of laboratory methods and specimen handling in clinical study reports. Statement by the Consortium of Laboratory Medicine Journal Editors.

Full disclosure in industry-sponsored laboratory medicine research studies: statement by the Consortium of Laboratory Medicine Journal Editors.
PubMed Identifier: 22686537
author list: Rifai N, Plebani M, Wu A, Brugnara C, Delvin E, Lamb EJ, Ness PM, Wick MR, Berg JP
published in: Transfusion
information resource reference: Full disclosure in industry-sponsored laboratory medicine research studies: statement by the Consortium of Laboratory Medicine Journal Editors. Transfusion. 2012 Jun; 52(6):e15-6.
journal title abbreviation: Transfusion
publication date: 2010-12-22T00:00:00
year: 2010
type: Academic Article
type: Article
type: Document
type: Information Resource

Expansion of host cellular niche can drive adaptation of a zoonotic malaria parasite to humans.
PubMed Identifier: 23535659
author list: Lim C, Hansen E, DeSimone TM, Moreno Y, Junker K, Bei A, Brugnara C, Buckee CO, Duraisingh MT
published in: Nature communications
information resource reference: Expansion of host cellular niche can drive adaptation of a zoonotic malaria parasite to humans. Nat Commun. 2013; 4:1638.
journal title abbreviation: Nat Commun
publication date: 2013-01-01T00:00:00
year: 2013
type: Academic Article
type: Article
type: Document
type: Information Resource

Clotrimazole and efaroxan inhibit red cell Gardos channel independently of imidazoline I1 and I2 binding sites.
PubMed Identifier: 8925867
author list: Coupry I, Armsby CC, Alper SL, Brugnara C, Parini A
published in: European journal of pharmacology
information resource reference: Clotrimazole and efaroxan inhibit red cell Gardos channel independently of imidazoline I1 and I2 binding sites. Eur J Pharmacol. 1996 Jan 04; 295(1):109-12.
journal title abbreviation: Eur J Pharmacol
publication date: 1996-01-04T00:00:00
year: 1996
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 104003
type: Authorship
author rank in publication: 4
linked author: Brugnara, Carlo
linked information resource: Removal of erythrocyte membrane iron in vivo ameliorates the pathobiology of murine thalassemia.

Inhibition of maxi-K currents in ferret portal vein smooth muscle cells by the antifungal clotrimazole.
PubMed Identifier: 9252441
author list: Rittenhouse AR, Parker C, Brugnara C, Morgan KG, Alper SL
published in: The American journal of physiology
information resource reference: Inhibition of maxi-K currents in ferret portal vein smooth muscle cells by the antifungal clotrimazole. Am J Physiol. 1997 Jul; 273(1 Pt 1):C45-56.
journal title abbreviation: Am J Physiol
publication date: 1997-07-01T00:00:00
year: 1997
type: Academic Article
type: Article
type: Document
type: Information Resource

K-Cl cotransport modulation by intracellular Mg in erythrocytes from mice bred for low and high Mg levels.
PubMed Identifier: 11546677
author list: De Franceschi L, Villa-Moruzzi E, Fumagalli L, Brugnara C, Turrini F, Motta R, Veghini E, Corato C, Alper SL, Berton G
published in: American journal of physiology. Cell physiology
information resource reference: K-Cl cotransport modulation by intracellular Mg in erythrocytes from mice bred for low and high Mg levels. Am J Physiol Cell Physiol. 2001 Oct; 281(4):C1385-95.
journal title abbreviation: Am J Physiol Cell Physiol
publication date: 2001-10-01T00:00:00
year: 2001
type: Academic Article
type: Article
type: Document
type: Information Resource

Preliminary assessment of inhaled nitric oxide for acute vaso-occlusive crisis in pediatric patients with sickle cell disease.
PubMed Identifier: 12622584
author list: Weiner DL, Hibberd PL, Betit P, Cooper AB, Botelho CA, Brugnara C
published in: JAMA
information resource reference: Preliminary assessment of inhaled nitric oxide for acute vaso-occlusive crisis in pediatric patients with sickle cell disease. JAMA. 2003 Mar 05; 289(9):1136-42.
journal title abbreviation: JAMA
publication date: 2003-03-05T00:00:00
year: 2003
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 100288
type: Authorship
author rank in publication: 1
linked author: Brugnara, Carlo
linked information resource: [Clinical trials of new therapeutic pharmacology for sickle cell disease].

Regulation of K-Cl cotransport during reticulocyte maturation and erythrocyte aging in normal and sickle erythrocytes.
PubMed Identifier: 12606312
author list: Bize I, Taher S, Brugnara C
published in: American journal of physiology. Cell physiology
information resource reference: Regulation of K-Cl cotransport during reticulocyte maturation and erythrocyte aging in normal and sickle erythrocytes. Am J Physiol Cell Physiol. 2003 Jul; 285(1):C31-8.
journal title abbreviation: Am J Physiol Cell Physiol
publication date: 2003-02-26T00:00:00
year: 2003
type: Academic Article
type: Article
type: Document
type: Information Resource