Albrecht DS, Ahmed SU, Kettner NW, Borra RJH, Cohen-Adad J, Deng H, Houle TT, Opalacz A, Roth SA, Melo MFV, Chen L, Mao J, Hooker JM, Loggia ML, Zhang Y
Neuroinflammation of the spinal cord and nerve roots in chronic radicular pain patients. Pain. 2018 May; 159(5):968-977.
Neuroinflammation of the spinal cord and nerve roots in chronic radicular pain patients.
Lee J, Protsenko E, Lazaridou A, Franceschelli O, Ellingsen DM, Mawla I, Isenburg K, Berry MP, Galenkamp L, Loggia ML, Wasan AD, Edwards RR, Napadow V
Arthritis & rheumatology (Hoboken, N.J.)
Encoding of Self-Referential Pain Catastrophizing in the Posterior Cingulate Cortex in Fibromyalgia. Arthritis Rheumatol. 2018 08; 70(8):1308-1318.
Encoding of Self-Referential Pain Catastrophizing in the Posterior Cingulate Cortex in Fibromyalgia.
Shelton KT, Qu J, Bilotta F, Brown EN, Cudemus G, D'Alessandro DA, Deng H, DiBiasio A, Gitlin JA, Hahm EY, Hobbs LE, Houle TT, Ibala R, Loggia ML, Pavone KJ, Shaefi S, Tolis G, Westover MB, Akeju O
Minimizing ICU Neurological Dysfunction with Dexmedetomidine-induced Sleep (MINDDS): protocol for a randomised, double-blind, parallel-arm, placebo-controlled trial. BMJ Open. 2018 04 20; 8(4):e020316.
Minimizing ICU Neurological Dysfunction with Dexmedetomidine-induced Sleep (MINDDS): protocol for a randomised, double-blind, parallel-arm, placebo-controlled trial.
Wasan AD, Loggia ML, Chen LQ, Napadow V, Kong J, Gollub RL
Neural correlates of chronic low back pain measured by arterial spin labeling. Anesthesiology. 2011 Aug; 115(2):364-74.
Neural correlates of chronic low back pain measured by arterial spin labeling.
Albrecht DS, Granziera C, Hooker JM, Loggia ML
Correction to In Vivo Imaging of Human Neuroinflammation. ACS Chem Neurosci. 2018 06 20; 9(6):1515.
Correction to In Vivo Imaging of Human Neuroinflammation.
Lois C, González I, Izquierdo-García D, Zürcher NR, Wilkens P, Loggia ML, Hooker JM, Rosas HD
Neuroinflammation in Huntington's Disease: New Insights with 11C-PBR28 PET/MRI. ACS Chem Neurosci. 2018 11 21; 9(11):2563-2571.
Neuroinflammation in Huntington's Disease: New Insights with 11C-PBR28 PET/MRI.
Alshikho MJ, Zürcher NR, Loggia ML, Cernasov P, Reynolds B, Pijanowski O, Chonde DB, Izquierdo Garcia D, Mainero C, Catana C, Chan J, Babu S, Paganoni S, Hooker JM, Atassi N
Integrated magnetic resonance imaging and [11 C]-PBR28 positron emission tomographic imaging in amyotrophic lateral sclerosis. Ann Neurol. 2018 06; 83(6):1186-1197.
Integrated magnetic resonance imaging and [11 C]-PBR28 positron emission tomographic imaging in amyotrophic lateral sclerosis.
Editorial: Functional Connectivity: Dissecting the Relationship Between the Brain and "Pain Centralization" in Rheumatoid Arthritis. Arthritis Rheumatol. 2018 07; 70(7):977-980.
Editorial: Functional Connectivity: Dissecting the Relationship Between the Brain and "Pain Centralization" in Rheumatoid Arthritis.
Chronic pain and opioid receptor availability: disentangling the molecular contributions and the "chicken or the egg" dilemma. Pain. 2018 09; 159(9):1679-1680.
Chronic pain and opioid receptor availability: disentangling the molecular contributions and the "chicken or the egg" dilemma.
Lee YC, Fine A, Protsenko E, Massarotti E, Edwards RR, Mawla I, Napadow V, Loggia ML
Brain Correlates of Continuous Pain in Rheumatoid Arthritis as Measured by Pulsed Arterial Spin Labeling. Arthritis Care Res (Hoboken). 2019 02; 71(2):308-318.
Brain Correlates of Continuous Pain in Rheumatoid Arthritis as Measured by Pulsed Arterial Spin Labeling.
Imaging neuroglial mechanisms of neuropathic pain-opioid interaction in HIV
Jensen KB, Berna C, Loggia ML, Wasan AD, Edwards RR, Gollub RL
The use of functional neuroimaging to evaluate psychological and other non-pharmacological treatments for clinical pain. Neurosci Lett. 2012 Jun 29; 520(2):156-64.
The use of functional neuroimaging to evaluate psychological and other non-pharmacological treatments for clinical pain.
Ratai EM, Alshikho MJ, Zürcher NR, Loggia ML, Cebulla CL, Cernasov P, Reynolds B, Fish J, Seth R, Babu S, Paganoni S, Hooker JM, Atassi N
Integrated imaging of [11C]-PBR28 PET, MR diffusion and magnetic resonance spectroscopy 1H-MRS in amyotrophic lateral sclerosis. Neuroimage Clin. 2018; 20:357-364.
Integrated imaging of [11C]-PBR28 PET, MR diffusion and magnetic resonance spectroscopy 1H-MRS in amyotrophic lateral sclerosis.
Brain Structural Alterations in Chronic Knee Osteoarthritis: What Can Treatment Effects Teach Us? Pain Med. 2018 11 01; 19(11):2099-2100.
Brain Structural Alterations in Chronic Knee Osteoarthritis: What Can Treatment Effects Teach Us?
Kong J, Loggia ML, Zyloney C, Tu P, LaViolette P, Gollub RL
Exploring the brain in pain: activations, deactivations and their relation. Pain. 2010 Feb; 148(2):257-267.
Exploring the brain in pain: activations, deactivations and their relation.
Loggia ML, Edwards RR, Kim J, Vangel MG, Wasan AD, Gollub RL, Harris RE, Park K, Napadow V
Disentangling linear and nonlinear brain responses to evoked deep tissue pain. Pain. 2012 Oct; 153(10):2140-2151.
Disentangling linear and nonlinear brain responses to evoked deep tissue pain.
Albrecht DS, Forsberg A, Sandström A, Bergan C, Kadetoff D, Protsenko E, Lampa J, Lee YC, Höglund CO, Catana C, Cervenka S, Akeju O, Lekander M, Cohen G, Halldin C, Taylor N, Kim M, Hooker JM, Edwards RR, Napadow V, Kosek E, Loggia ML
Brain glial activation in fibromyalgia - A multi-site positron emission tomography investigation. Brain Behav Immun. 2019 01; 75:72-83.
Brain glial activation in fibromyalgia - A multi-site positron emission tomography investigation.
Loggia ML, Kim J, Gollub RL, Vangel MG, Kirsch I, Kong J, Wasan AD, Napadow V
Default mode network connectivity encodes clinical pain: an arterial spin labeling study. Pain. 2013 Jan; 154(1):24-33.
Default mode network connectivity encodes clinical pain: an arterial spin labeling study.
Campbell CM, Witmer K, Simango M, Carteret A, Loggia ML, Campbell JN, Haythornthwaite JA, Edwards RR
Catastrophizing delays the analgesic effect of distraction. Pain. 2010 May; 149(2):202-207.
Catastrophizing delays the analgesic effect of distraction.
Ellingsen DM, Napadow V, Protsenko E, Mawla I, Kowalski MH, Swensen D, O'Dwyer-Swensen D, Edwards RR, Kettner N, Loggia ML
Brain Mechanisms of Anticipated Painful Movements and Their Modulation by Manual Therapy in Chronic Low Back Pain. J Pain. 2018 11; 19(11):1352-1365.
Brain Mechanisms of Anticipated Painful Movements and Their Modulation by Manual Therapy in Chronic Low Back Pain.
Paganoni S, Alshikho MJ, Luppino S, Chan J, Pothier L, Schoenfeld D, Andres PL, Babu S, Zürcher NR, Loggia ML, Barry RL, Luotti S, Nardo G, Trolese MC, Pantalone S, Bendotti C, Bonetto V, De Marchi F, Rosen B, Hooker J, Cudkowicz M, Atassi N
A pilot trial of RNS60 in amyotrophic lateral sclerosis. Muscle Nerve. 2019 03; 59(3):303-308.
A pilot trial of RNS60 in amyotrophic lateral sclerosis.
Lee J, Mawla I, Kim J, Loggia ML, Ortiz A, Jung C, Chan ST, Gerber J, Schmithorst VJ, Edwards RR, Wasan AD, Berna C, Kong J, Kaptchuk TJ, Gollub RL, Rosen BR, Napadow V
Machine learning-based prediction of clinical pain using multimodal neuroimaging and autonomic metrics. Pain. 2019 Mar; 160(3):550-560.
Machine learning-based prediction of clinical pain using multimodal neuroimaging and autonomic metrics.
Gilbert TM, Zürcher NR, Wu CJ, Bhanot A, Hightower BG, Kim M, Albrecht DS, Wey HY, Schroeder FA, Rodriguez-Thompson A, Morin TM, Hart KL, Pellegrini AM, Riley MM, Wang C, Stufflebeam SM, Haggarty SJ, Holt DJ, Loggia ML, Perlis RH, Brown HE, Roffman JL, Hooker JM
PET neuroimaging reveals histone deacetylase dysregulation in schizophrenia. J Clin Invest. 2019 01 02; 129(1):364-372.
PET neuroimaging reveals histone deacetylase dysregulation in schizophrenia.
Multi-parameter autonomic-based pain assessment: more is more? Pain. 2012 Sep; 153(9):1779-1780.
Multi-parameter autonomic-based pain assessment: more is more?
Kim J, Mawla I, Kong J, Lee J, Gerber J, Ortiz A, Kim H, Chan ST, Loggia ML, Wasan AD, Edwards RR, Gollub RL, Rosen BR, Napadow V
Somatotopically specific primary somatosensory connectivity to salience and default mode networks encodes clinical pain. Pain. 2019 07; 160(7):1594-1605.
Somatotopically specific primary somatosensory connectivity to salience and default mode networks encodes clinical pain.
Albrecht DS, Mainero C, Ichijo E, Ward N, Granziera C, Zürcher NR, Akeju O, Bonnier G, Price J, Hooker JM, Napadow V, Loggia ML, Hadjikhani N
Imaging of neuroinflammation in migraine with aura: A [11C]PBR28 PET/MRI study. Neurology. 2019 04 23; 92(17):e2038-e2050.
Imaging of neuroinflammation in migraine with aura: A [11C]PBR28 PET/MRI study.
Barletta VT, Herranz E, Treaba CA, Ouellette R, Mehndiratta A, Loggia ML, Klawiter EC, Ionete C, Jacob SA, Mainero C
Multiple sclerosis (Houndmills, Basingstoke, England)
Evidence of diffuse cerebellar neuroinflammation in multiple sclerosis by 11C-PBR28 MR-PET. Mult Scler. 2020 05; 26(6):668-678.
Evidence of diffuse cerebellar neuroinflammation in multiple sclerosis by 11C-PBR28 MR-PET.
Dr. Henry Isaiah Dorr Professor of Research and Teaching in Anaesthetics and Anaesthesia
Associate Professor of Radiology, Part-time
Hodges PW, Barbe MF, Loggia ML, Nijs J, Stone LS
The Journal of orthopaedic and sports physical therapy
Diverse Role of Biological Plasticity in Low Back Pain and Its Impact on Sensorimotor Control of the Spine. J Orthop Sports Phys Ther. 2019 Jun; 49(6):389-401.
Diverse Role of Biological Plasticity in Low Back Pain and Its Impact on Sensorimotor Control of the Spine.
Albrecht DS, Kim M, Akeju O, Torrado-Carvajal A, Edwards RR, Zhang Y, Bergan C, Protsenko E, Kucyi A, Wasan AD, Hooker JM, Napadow V, Loggia ML
The neuroinflammatory component of negative affect in patients with chronic pain. Mol Psychiatry. 2021 03; 26(3):864-874.
The neuroinflammatory component of negative affect in patients with chronic pain.
A Study of Neuroimmune Mechanisms of Poststroke Fatigue using Integrated PET/MRI
Professor of Psychology in the Department of Psychiatry
Professor of Physical Medicine and Rehabilitation
Herranz E, Louapre C, Treaba CA, Govindarajan ST, Ouellette R, Mangeat G, Loggia ML, Cohen-Adad J, Klawiter EC, Sloane JA, Mainero C
Profiles of cortical inflammation in multiple sclerosis by 11C-PBR28 MR-PET and 7 Tesla imaging. Mult Scler. 2020 10; 26(12):1497-1509.
Profiles of cortical inflammation in multiple sclerosis by 11C-PBR28 MR-PET and 7 Tesla imaging.
Loggia ML, Segerdahl AR, Howard MA, Tracey I
Imaging Clinically Relevant Pain States Using Arterial Spin Labeling. Pain Rep. 2019 May 15; 4(4).
Imaging Clinically Relevant Pain States Using Arterial Spin Labeling.
Jung C, Ichesco E, Ratai EM, Gonzalez RG, Burdo T, Loggia ML, Harris RE, Napadow V
Magnetic resonance imaging of neuroinflammation in chronic pain: a role for astrogliosis? Pain. 2020 07; 161(7):1555-1564.
Magnetic resonance imaging of neuroinflammation in chronic pain: a role for astrogliosis?
Alshelh Z, Albrecht DS, Bergan C, Akeju O, Clauw DJ, Conboy L, Edwards RR, Kim M, Lee YC, Protsenko E, Napadow V, Sullivan K, Loggia ML
In-vivo imaging of neuroinflammation in veterans with Gulf War illness. Brain Behav Immun. 2020 07; 87:498-507.
In-vivo imaging of neuroinflammation in veterans with Gulf War illness.
Hubbard CS, Lazaridou A, Cahalan CM, Kim J, Edwards RR, Napadow V, Loggia ML
Aberrant Salience? Brain Hyperactivation in Response to Pain Onset and Offset in Fibromyalgia. Arthritis Rheumatol. 2020 07; 72(7):1203-1213.
Aberrant Salience? Brain Hyperactivation in Response to Pain Onset and Offset in Fibromyalgia.
Zürcher NR, Loggia ML, Mullett JE, Tseng C, Bhanot A, Richey L, Hightower BG, Wu C, Parmar AJ, Butterfield RI, Dubois JM, Chonde DB, Izquierdo-Garcia D, Wey HY, Catana C, Hadjikhani N, McDougle CJ, Hooker JM
[11C]PBR28 MR-PET imaging reveals lower regional brain expression of translocator protein (TSPO) in young adult males with autism spectrum disorder. Mol Psychiatry. 2021 05; 26(5):1659-1669.
[11C]PBR28 MR-PET imaging reveals lower regional brain expression of translocator protein (TSPO) in young adult males with autism spectrum disorder.
Kim M, Mawla I, Albrecht DS, Admon R, Torrado-Carvajal A, Bergan C, Protsenko E, Kumar P, Edwards RR, Saha A, Napadow V, Pizzagalli DA, Loggia ML
Striatal hypofunction as a neural correlate of mood alterations in chronic pain patients. Neuroimage. 2020 05 01; 211:116656.
Striatal hypofunction as a neural correlate of mood alterations in chronic pain patients.
Van Weehaeghe D, Babu S, De Vocht J, Zürcher NR, Chew S, Tseng CJ, Loggia ML, Koole M, Rezaei A, Schramm G, Van Damme P, Hooker JM, Van Laere K, Atassi N
Journal of nuclear medicine : official publication, Society of Nuclear Medicine
Moving Toward Multicenter Therapeutic Trials in Amyotrophic Lateral Sclerosis: Feasibility of Data Pooling Using Different Translocator Protein PET Radioligands. J Nucl Med. 2020 11; 61(11):1621-1627.
Moving Toward Multicenter Therapeutic Trials in Amyotrophic Lateral Sclerosis: Feasibility of Data Pooling Using Different Translocator Protein PET Radioligands.
Hadjikhani N, Albrecht DS, Mainero C, Ichijo E, Ward N, Granziera C, Zürcher NR, Akeju O, Bonnier G, Price J, Hooker JM, Napadow V, Nahrendorf M, Loggia ML, Moskowitz MA
Extra-Axial Inflammatory Signal in Parameninges in Migraine with Visual Aura. Ann Neurol. 2020 06; 87(6):939-949.
Extra-Axial Inflammatory Signal in Parameninges in Migraine with Visual Aura.
Kim H, Mawla I, Lee J, Gerber J, Walker K, Kim J, Ortiz A, Chan ST, Loggia ML, Wasan AD, Edwards RR, Kong J, Kaptchuk TJ, Gollub RL, Rosen BR, Napadow V
Reduced tactile acuity in chronic low back pain is linked with structural neuroplasticity in primary somatosensory cortex and is modulated by acupuncture therapy. Neuroimage. 2020 08 15; 217:116899.
Reduced tactile acuity in chronic low back pain is linked with structural neuroplasticity in primary somatosensory cortex and is modulated by acupuncture therapy.
Torrado-Carvajal A, Albrecht DS, Lee J, Andronesi OC, Ratai EM, Napadow V, Loggia ML
Inpainting as a Technique for Estimation of Missing Voxels in Brain Imaging. Ann Biomed Eng. 2021 Jan; 49(1):345-353.
Inpainting as a Technique for Estimation of Missing Voxels in Brain Imaging.
Katsumi Y, Racine AM, Torrado-Carvajal A, Loggia ML, Hooker JM, Greve DN, Hightower BG, Catana C, Cavallari M, Arnold SE, Fong TG, Vasunilashorn SM, Marcantonio ER, Schmitt EM, Xu G, Libermann TA, Barrett LF, Inouye SK, Dickerson BC, Touroutoglou A, Collins JA
The Role of Inflammation after Surgery for Elders (RISE) study: Examination of [11C]PBR28 binding and exploration of its link to post-operative delirium. Neuroimage Clin. 2020; 27:102346.
The Role of Inflammation after Surgery for Elders (RISE) study: Examination of [11C]PBR28 binding and exploration of its link to post-operative delirium.
Torrado-Carvajal A, Toschi N, Albrecht DS, Chang K, Akeju O, Kim M, Edwards RR, Zhang Y, Hooker JM, Duggento A, Kalpathy-Cramer J, Napadow V, Loggia ML
Thalamic neuroinflammation as a reproducible and discriminating signature for chronic low back pain. Pain. 2021 04 01; 162(4):1241-1249.
Thalamic neuroinflammation as a reproducible and discriminating signature for chronic low back pain.
Rapalino O, Weerasekera A, Moum SJ, Eikermann-Haerter K, Edlow BL, Fischer D, Torrado-Carvajal A, Loggia ML, Mukerji SS, Schaefer PW, Gonzalez RG, Lev MH, Ratai EM
AJNR. American journal of neuroradiology
Brain MR Spectroscopic Findings in 3 Consecutive Patients with COVID-19: Preliminary Observations. AJNR Am J Neuroradiol. 2021 01; 42(1):37-41.
Brain MR Spectroscopic Findings in 3 Consecutive Patients with COVID-19: Preliminary Observations.
Grace PM, Tawfik VL, Svensson CI, Burton MD, Loggia ML, Hutchinson MR
The Journal of neuroscience : the official journal of the Society for Neuroscience
The Neuroimmunology of Chronic Pain: From Rodents to Humans. J Neurosci. 2021 02 03; 41(5):855-865.
The Neuroimmunology of Chronic Pain: From Rodents to Humans.
Isenburg K, Mawla I, Loggia ML, Ellingsen DM, Protsenko E, Kowalski MH, Swensen D, O'Dwyer-Swensen D, Edwards RR, Napadow V, Kettner N
Increased Salience Network Connectivity Following Manual Therapy is Associated with Reduced Pain in Chronic Low Back Pain Patients. J Pain. 2021 05; 22(5):545-555.
Increased Salience Network Connectivity Following Manual Therapy is Associated with Reduced Pain in Chronic Low Back Pain Patients.
Weerasekera A, Morrissey E, Kim M, Saha A, Lin Y, Alshelh Z, Torrado-Carvajal A, Albrecht D, Akeju O, Kwon YM, Bedair H, Chen AF, Napadow V, Schreiber K, Ratai EM, Edwards RR, Loggia ML
Thalamic neurometabolite alterations in patients with knee osteoarthritis before and after total knee replacement. Pain. 2021 07 01; 162(7):2014-2023.
Thalamic neurometabolite alterations in patients with knee osteoarthritis before and after total knee replacement.
Evaluation of Cannabidiol for Reduction of Brain Neuroinflammation
Lee J, Andronesi OC, Torrado-Carvajal A, Ratai EM, Loggia ML, Weerasekera A, Berry MP, Ellingsen DM, Isaro L, Lazaridou A, Paschali M, Grahl A, Wasan AD, Edwards RR, Napadow V
European journal of pain (London, England)
3D magnetic resonance spectroscopic imaging reveals links between brain metabolites and multidimensional pain features in fibromyalgia. Eur J Pain. 2021 10; 25(9):2050-2064.
3D magnetic resonance spectroscopic imaging reveals links between brain metabolites and multidimensional pain features in fibromyalgia.
Sander CY, Bovo S, Torrado-Carvajal A, Albrecht D, Deng H, Napadow V, Price JC, Hooker JM, Loggia ML
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism
[11C]PBR28 radiotracer kinetics are not driven by alterations in cerebral blood flow. J Cereb Blood Flow Metab. 2021 11; 41(11):3069-3084.
[11C]PBR28 radiotracer kinetics are not driven by alterations in cerebral blood flow.
Keating D, Zundel CG, Abreu M, Krengel M, Aenlle K, Nichols MD, Toomey R, Chao LL, Golier J, Abdullah L, Quinn E, Heeren T, Groh JR, Koo BB, Killiany R, Loggia ML, Younger J, Baraniuk J, Janulewicz P, Ajama J, Quay M, Baas PW, Qiang L, Conboy L, Kokkotou E, O'Callaghan JP, Steele L, Klimas N, Sullivan K
Boston biorepository, recruitment and integrative network (BBRAIN): A resource for the Gulf War Illness scientific community. Life Sci. 2021 Nov 01; 284:119903.
Boston biorepository, recruitment and integrative network (BBRAIN): A resource for the Gulf War Illness scientific community.
Alshelh Z, Brusaferri L, Saha A, Morrissey E, Knight P, Kim M, Zhang Y, Hooker JM, Albrecht D, Torrado-Carvajal A, Placzek MS, Akeju O, Price J, Edwards RR, Lee J, Sclocco R, Catana C, Napadow V, Loggia ML
Neuroimmune signatures in chronic low back pain subtypes. Brain. 2022 04 29; 145(3):1098-1110.
Neuroimmune signatures in chronic low back pain subtypes.
Martins D, Dipasquale O, Veronese M, Turkheimer F, Loggia ML, McMahon S, Howard MA, Williams SCR
Transcriptional and cellular signatures of cortical morphometric remodelling in chronic pain. Pain. 2022 06 01; 163(6):e759-e773.
Transcriptional and cellular signatures of cortical morphometric remodelling in chronic pain.
Schaechter JD, Hightower BG, Kim M, Loggia ML
A pilot [11C]PBR28 PET/MRI study of neuroinflammation and neurodegeneration in chronic stroke patients. Brain Behav Immun Health. 2021 Nov; 17:100336.
A pilot [11C]PBR28 PET/MRI study of neuroinflammation and neurodegeneration in chronic stroke patients.
Barowsky S, Jung JY, Nesbit N, Silberstein M, Fava M, Loggia ML, Smoller JW, Lee PH
Cross-Disorder Genomics Data Analysis Elucidates a Shared Genetic Basis Between Major Depression and Osteoarthritis Pain. Front Genet. 2021; 12:687687.
Cross-Disorder Genomics Data Analysis Elucidates a Shared Genetic Basis Between Major Depression and Osteoarthritis Pain.
Paschali M, Lazaridou A, Vilsmark ES, Lee J, Berry M, Grahl A, Anzolin A, Loggia M, Napadow V, Edwards RR
The "self" in pain: high levels of schema-enmeshment worsen fibromyalgia impact. BMC Musculoskelet Disord. 2021 Oct 12; 22(1):871.
The "self" in pain: high levels of schema-enmeshment worsen fibromyalgia impact.
Cheng CH, Alshelh Z, Guan Y, Sullivan K, Loggia ML, Koo BB
Association of the tissue microstructural diffusivity and translocator protein PET in Gulf War Illness. Brain Behav Immun Health. 2021 Dec; 18:100364.
Association of the tissue microstructural diffusivity and translocator protein PET in Gulf War Illness.
Cheng JC, Anzolin A, Berry M, Honari H, Paschali M, Lazaridou A, Lee J, Ellingsen DM, Loggia ML, Grahl A, Lindquist MA, Edwards RR, Napadow V
Dynamic Functional Brain Connectivity Underlying Temporal Summation of Pain in Fibromyalgia. Arthritis Rheumatol. 2022 04; 74(4):700-710.
Dynamic Functional Brain Connectivity Underlying Temporal Summation of Pain in Fibromyalgia.
Sari H, Galbusera R, Bonnier G, Lin Y, Alshelh Z, Torrado-Carvajal A, Mukerji SS, Ratai EM, Gandhi RT, Chu JT, Akeju O, Orhurhu V, Salvatore AN, Sherman J, Kwon DS, Walker B, Rosen B, Price JC, Pollak LE, Loggia ML, Granziera C
Neurology(R) neuroimmunology & neuroinflammation
Multimodal Investigation of Neuroinflammation in Aviremic Patients With HIV on Antiretroviral Therapy and HIV Elite Controllers. Neurol Neuroimmunol Neuroinflamm. 2022 03; 9(2).
Multimodal Investigation of Neuroinflammation in Aviremic Patients With HIV on Antiretroviral Therapy and HIV Elite Controllers.
Brusaferri L, Alshelh Z, Martins D, Kim M, Weerasekera A, Housman H, Morrissey EJ, Knight PC, Castro-Blanco KA, Albrecht DS, Tseng CE, Zürcher NR, Ratai EM, Akeju O, Makary MM, Catana C, Mercaldo ND, Hadjikhani N, Veronese M, Turkheimer F, Rosen BR, Hooker JM, Loggia ML
The pandemic brain: Neuroinflammation in non-infected individuals during the COVID-19 pandemic. Brain Behav Immun. 2022 05; 102:89-97.
The pandemic brain: Neuroinflammation in non-infected individuals during the COVID-19 pandemic.
Ibinson JW, Gillman AG, Schmidthorst V, Li C, Napadow V, Loggia ML, Wasan AD
Comparison of test-retest reliability of BOLD and pCASL fMRI in a two-center study. BMC Med Imaging. 2022 04 03; 22(1):62.
Comparison of test-retest reliability of BOLD and pCASL fMRI in a two-center study.
Carriere JS, Martel MO, Loggia ML, Campbell CM, Smith MT, Haythornthwaite JA, Edwards RR
The Influence of Expectancies on Pain and Function Over Time After Total Knee Arthroplasty. Pain Med. 2022 09 30; 23(10):1767-1776.
The Influence of Expectancies on Pain and Function Over Time After Total Knee Arthroplasty.
Schaechter JD, Kim M, Hightower BG, Ragas T, Loggia ML
Disruptions in Structural and Functional Connectivity Relate to Poststroke Fatigue. Brain Connect. 2023 02; 13(1):15-27.
Disruptions in Structural and Functional Connectivity Relate to Poststroke Fatigue.
Barry RL, Torrado-Carvajal A, Kirsch JE, Arabasz GE, Albrecht DS, Alshelh Z, Pijanowski O, Lewis AJ, Keegan M, Reynolds B, Knight PC, Morrissey EJ, Loggia ML, Atassi N, Hooker JM, Babu S
Selective atrophy of the cervical enlargement in whole spinal cord MRI of amyotrophic lateral sclerosis. Neuroimage Clin. 2022; 36:103199.
Selective atrophy of the cervical enlargement in whole spinal cord MRI of amyotrophic lateral sclerosis.
Pike CK, Kim M, Schnitzer K, Mercaldo N, Edwards R, Napadow V, Zhang Y, Morrissey EJ, Alshelh Z, Evins AE, Loggia ML, Gilman JM
Study protocol for a phase II, double-blind, randomised controlled trial of cannabidiol (CBD) compared with placebo for reduction of brain neuroinflammation in adults with chronic low back pain. BMJ Open. 2022 09 19; 12(9):e063613.
Study protocol for a phase II, double-blind, randomised controlled trial of cannabidiol (CBD) compared with placebo for reduction of brain neuroinflammation in adults with chronic low back pain.
Zhu Y, Loggia ML, Edwards RR, Flowers KM, Muñoz-Vergara DW, Partridge AH, Schreiber KL
Increased Clinical Pain Locations and Pain Sensitivity in Women After Breast Cancer Surgery: Influence of Aromatase Inhibitor Therapy. Clin J Pain. 2022 12 01; 38(12):721-729.
Increased Clinical Pain Locations and Pain Sensitivity in Women After Breast Cancer Surgery: Influence of Aromatase Inhibitor Therapy.
Turkheimer FE, Liu J, Fagerholm ED, Dazzan P, Loggia ML, Bettelheim E
The art of pain: A quantitative color analysis of the self-portraits of Frida Kahlo. Front Hum Neurosci. 2022; 16:1000656.
The art of pain: A quantitative color analysis of the self-portraits of Frida Kahlo.
Bartolo ND, Reid SE, Krishnan HS, Haseki A, Renganathan M, Largent-Milnes TM, Norwood BA, Loggia ML, Hooker JM
Radiocaine: An Imaging Marker of Neuropathic Injury. ACS Chem Neurosci. 2022 12 21; 13(24):3661-3667.
Radiocaine: An Imaging Marker of Neuropathic Injury.
Morrissey EJ, Alshelh Z, Knight PC, Saha A, Kim M, Torrado-Carvajal A, Zhang Y, Edwards RR, Pike C, Locascio JJ, Napadow V, Loggia ML
Assessing the potential anti-neuroinflammatory effect of minocycline in chronic low back pain: Protocol for a randomized, double-blind, placebo-controlled trial. Contemp Clin Trials. 2023 03; 126:107087.
Assessing the potential anti-neuroinflammatory effect of minocycline in chronic low back pain: Protocol for a randomized, double-blind, placebo-controlled trial.
Mauck MC, Lotz J, Psioda MA, Carey TS, Clauw DJ, Majumdar S, Marras WS, Vo N, Aylward A, Hoffmeyer A, Zheng P, Ivanova A, McCumber M, Carson C, Anstrom KJ, Bowden AE, Dalton D, Derr L, Dufour J, Fields AJ, Fritz J, Hassett AL, Harte SE, Hue TF, Krug R, Loggia ML, Mageswaran P, McLean SA, Mitchell UH, O'Neill C, Pedoia V, Quirk DA, Rhon DI, Rieke V, Shah L, Sowa G, Spiegel B, Wasan AD, Wey HM, LaVange L
The Back Pain Consortium (BACPAC) Research Program: Structure, Research Priorities, and Methods. Pain Med. 2023 08 04; 24(Suppl 1):S3-S12.
The Back Pain Consortium (BACPAC) Research Program: Structure, Research Priorities, and Methods.
Weerasekera A, Knight PC, Alshelh Z, Morrissey EJ, Kim M, Zhang Y, Napadow V, Anzolin A, Torrado-Carvajal A, Edwards RR, Ratai EM, Loggia ML
Thalamic neurometabolite alterations in chronic low back pain: a common phenomenon across musculoskeletal pain conditions? Pain. 2024 Jan 01; 165(1):126-134.
Thalamic neurometabolite alterations in chronic low back pain: a common phenomenon across musculoskeletal pain conditions?
Arsava EM, Chang K, Tawakol A, Loggia ML, Goldstein JN, Brown J, Park KY, Singhal AB, Kalpathy-Cramer J, Sorensen AG, Rosen BR, Samuels MA, Ay H
Stroke-Related Visceral Alterations: A Voxel-Based Neuroanatomic Localization Study. Ann Neurol. 2023 12; 94(6):1155-1163.
Stroke-Related Visceral Alterations: A Voxel-Based Neuroanatomic Localization Study.
Lee J, Lazaridou A, Paschali M, Loggia ML, Berry MP, Ellingsen DM, Isenburg K, Anzolin A, Grahl A, Wasan AD, Napadow V, Edwards RR
A Randomized Controlled Neuroimaging Trial of Cognitive Behavioral Therapy for Fibromyalgia Pain. Arthritis Rheumatol. 2024 01; 76(1):130-140.
A Randomized Controlled Neuroimaging Trial of Cognitive Behavioral Therapy for Fibromyalgia Pain.
VanElzakker MB, Bues HF, Brusaferri L, Kim M, Saadi D, Ratai EM, Dougherty DD, Loggia ML
bioRxiv : the preprint server for biology
Neuroinflammation in post-acute sequelae of COVID-19 (PASC) as assessed by [11C]PBR28 PET correlates with vascular disease measures. bioRxiv. 2023 Oct 20.
Neuroinflammation in post-acute sequelae of COVID-19 (PASC) as assessed by [11C]PBR28 PET correlates with vascular disease measures.
Sandström A, Torrado-Carvajal A, Morrissey EJ, Kim M, Alshelh Z, Zhu Y, Li MD, Chang CY, Jarraya M, Akeju O, Schrepf A, Harris RE, Kwon YM, Bedair H, Chen AF, Mercaldo ND, Kettner N, Napadow V, Toschi N, Edwards RR, Loggia ML
[ 11 C]-PBR28 positron emission tomography signal as an imaging marker of joint inflammation in knee osteoarthritis. Pain. 2024 May 01; 165(5):1121-1130.
[ 11 C]-PBR28 positron emission tomography signal as an imaging marker of joint inflammation in knee osteoarthritis.
Brusaferri L, Alshelh Z, Schnieders JH, Sandström A, Mohammadian M, Morrissey EJ, Kim M, Chane CA, Grmek GC, Murphy JP, Bialobrzewski J, DiPietro A, Klinke J, Zhang Y, Torrado-Carvajal A, Mercaldo N, Akeju O, Wu O, Rosen BR, Napadow V, Hadjikhani N, Loggia ML
Neuroimmune activation and increased brain aging in chronic pain patients after the COVID-19 pandemic onset. Brain Behav Immun. 2024 02; 116:259-266.
Neuroimmune activation and increased brain aging in chronic pain patients after the COVID-19 pandemic onset.
From Nerve to Brain: Toward a Mechanistic Understanding of Spinal Cord Stimulation in Human Subjects
In-vivo Assessment of Neuroinflammation in Painful Trigeminal Neuropathy
Herranz E, Treaba CA, Barletta VT, Mehndiratta A, Ouellette R, Sloane JA, Ionete C, Babu S, Mastantuono M, Magon S, Loggia ML, Makary MM, Hooker JM, Catana C, Kinkel RP, Nicholas R, Klawiter EC, Magliozzi R, Mainero C
Characterization of cortico-meningeal translocator protein expression in multiple sclerosis. Brain. 2024 Jul 05; 147(7):2566-2578.
Characterization of cortico-meningeal translocator protein expression in multiple sclerosis.
The role of neuroinflammation in human peripheral neuropathic pain
Yoo CH, Rani N, Shen S, Loggia ML, Gaynor K, Moore KE, Bagdasarian FA, Lin YS, Edwards RR, Price JC, Hooker JM, Wey HY
Investigating neuroepigenetic alterations in chronic low back pain with positron emission tomography. Pain. 2024 Nov 01; 165(11):2586-2594.
Investigating neuroepigenetic alterations in chronic low back pain with positron emission tomography.
Neuroinflammation in post-acute sequelae of COVID-19 (PASC) as assessed by [11C]PBR28 PET correlates with vascular disease measures. Brain Behav Immun. 2024 Jul; 119:713-723.
Shraim MA, Massé-Alarie H, Farrell MJ, Cavaleri R, Loggia ML, Hodges PW
Neuroinflammatory activation in sensory and motor regions of the cortex is related to sensorimotor function in individuals with low back pain maintained by nociplastic mechanisms: A preliminary proof-of-concept study. Eur J Pain. 2024 Oct; 28(9):1607-1626.
Neuroinflammatory activation in sensory and motor regions of the cortex is related to sensorimotor function in individuals with low back pain maintained by nociplastic mechanisms: A preliminary proof-of-concept study.
Quidé Y, Jahanshad N, Andoh J, Antoniou G, Apkarian AV, Ashar YK, Badran BW, Baird CL, Baxter L, Bell TR, Blanco-Hinojo L, Borckardt J, Cheung CL, Ciampi de Andrade D, Couto BA, Cox SR, Cruz-Almeida Y, Dannlowski U, De Martino E, de Tommaso M, Deus J, Domin M, Egorova-Brumley N, Elliott J, Fanton S, Fauchon C, Flor H, Franz CE, Gatt JM, Gerdhem P, Gilman JM, Gollub RL, Govind V, Graven-Nielsen T, Håkansson G, Hales T, Haswell C, Heukamp NJ, Hu L, Huang L, Hussain A, Jensen K, Kircher T, Kremen WS, Leehr EJ, Lindquist M, Loggia ML, Lotze M, Martucci KT, Meeker TJ, Meinert S, Millard SK, Morey RA, Murillo C, Nees F, Nenadic I, Park HRP, Peng X, Ploner M, Pujol J, Robayo LE, Salan T, Seminowicz DA, Serian A, Slater R, Stein F, Stevens J, Strauss S, Sun D, Vachon-Presseau E, Valdes-Hernandez PA, Vanneste S, Vernon M, Verriotis M, Wager TD, Widerstrom-Noga E, Woodbury A, Zeidan F, Bhatt RR, Ching CRK, Haddad E, Thomopoulos SI, Thompson PM, Gustin SM
ENIGMA-Chronic Pain: a worldwide initiative to identify brain correlates of chronic pain. Pain. 2024 Dec 01; 165(12):2662-2666.
ENIGMA-Chronic Pain: a worldwide initiative to identify brain correlates of chronic pain.
Maccioni L, Michelle CM, Brusaferri L, Silvestri E, Bertoldo A, Schubert JJ, Nettis MA, Mondelli V, Howes O, Turkheimer FE, Bottlaender M, Bodini B, Stankoff B, Loggia ML, Veronese M
A blood-free modeling approach for the quantification of the blood-to-brain tracer exchange in TSPO PET imaging. Front Neurosci. 2024; 18:1395769.
A blood-free modeling approach for the quantification of the blood-to-brain tracer exchange in TSPO PET imaging.
Ferrante M, Inglese M, Brusaferri L, Whitehead AC, Maccioni L, Turkheimer FE, Nettis MA, Mondelli V, Howes O, Loggia ML, Veronese M, Toschi N
Computer methods and programs in biomedicine
Physically informed deep neural networks for metabolite-corrected plasma input function estimation in dynamic PET imaging. Comput Methods Programs Biomed. 2024 Nov; 256:108375.
Physically informed deep neural networks for metabolite-corrected plasma input function estimation in dynamic PET imaging.
Cazuza RA, Zagrai SM, Grieco AR, Avery TD, Abell AD, Wey HY, Loggia ML, Grace PM
18 kDa Translocator protein (TSPO) is upregulated in rat brain after peripheral nerve injury and downregulated by diroximel fumarate. Brain Behav Immun. 2025 Jan; 123:11-27.
18 kDa Translocator protein (TSPO) is upregulated in rat brain after peripheral nerve injury and downregulated by diroximel fumarate.
Kim J, Loggia ML, Edwards RR, Wasan AD, Gollub RL, Napadow V
Sustained deep-tissue pain alters functional brain connectivity. Pain. 2013 Aug; 154(8):1343-51.
Sustained deep-tissue pain alters functional brain connectivity.
Treaba CA, Herranz E, Barletta VT, Mehndiratta A, Sloane JA, Granberg T, Miscioscia A, Bomprezzi R, Loggia ML, Mainero C
Phenotyping in vivo chronic inflammation in multiple sclerosis by combined 11C-PBR28 MR-PET and 7T susceptibility-weighted imaging. Mult Scler. 2024 Dec; 30(14):1755-1764.
Phenotyping in vivo chronic inflammation in multiple sclerosis by combined 11C-PBR28 MR-PET and 7T susceptibility-weighted imaging.
"Neuroinflammation": does it have a role in chronic pain? Evidence from human imaging. Pain. 2024 Nov 01; 165(11S):S58-S67.
"Neuroinflammation": does it have a role in chronic pain? Evidence from human imaging.
Eiff B, Bullmore ET, Clatworthy MR, Fryer TD, Pariante CM, Mondelli V, Maccioni L, Hadjikhani N, Loggia ML, Moskowitz MA, Bruner E, Veronese M, Turkheimer FE, Schubert JJ
Extra-axial inflammatory signal and its relationship to peripheral and central immunity in depression. Brain. 2025 Feb 03; 148(2):635-646.
Extra-axial inflammatory signal and its relationship to peripheral and central immunity in depression.
Tohyama S, Datko M, Brusaferri L, Kinder LD, Schnieders JH, Hyman M, Goldstein AM, Gilbert MD, Housman H, Le V, Round K, Marin F, Heffernan MR, Garcia RG, Gollub RL, Edwards RR, Rosen BR, Hadjikhani N, Cheng HT, Schuman-Olivier Z, Loggia ML, Napadow V
Trigeminal nerve microstructure is linked with neuroinflammation and brainstem activity in migraine. Brain. 2025 Jul 07; 148(7):2551-2562.
Trigeminal nerve microstructure is linked with neuroinflammation and brainstem activity in migraine.
Maccioni L, Brusaferri L, Barzon L, Schubert JJ, Nettis MA, Cousins O, Rosenzweig I, Mizuno Y, Vicente-Rodríguez M, Singh N, Marques TR, Harrison NA, Fryer T, Bullmore ET, Cash D, Mondelli V, Pariante C, Howes O, Turkheimer FE, Loggia ML, Veronese M
A novel blood-free analytical framework for the quantification of neuroinflammatory load from TSPO PET Imaging. Res Sq. 2025 Feb 03.
A novel blood-free analytical framework for the quantification of neuroinflammatory load from TSPO PET Imaging.
Mohammadian M, Morrissey EJ, Knight PC, Brusaferri L, Kim M, Efthimiou N, Murphy JP, Alshelh Z, Grmek G, Schnieders JH, Chane CA, Sandström A, Catana C, Gilman JM, Locascio JJ, Edwards RR, Zhang Y, Napadow V, Loggia ML
Investigating the potential of minocycline in reducing brain inflammation in chronic low back pain: a randomized, placebo-controlled mechanistic clinical trial. Pain. 2025 Apr 09.
Investigating the potential of minocycline in reducing brain inflammation in chronic low back pain: a randomized, placebo-controlled mechanistic clinical trial.
Kong J, Spaeth RB, Wey HY, Cheetham A, Cook AH, Jensen K, Tan Y, Liu H, Wang D, Loggia ML, Napadow V, Smoller JW, Wasan AD, Gollub RL
S1 is associated with chronic low back pain: a functional and structural MRI study. Mol Pain. 2013 Aug 21; 9:43.
S1 is associated with chronic low back pain: a functional and structural MRI study.
Alshelh Z, Brusaferri L, Morrissey EJ, Torrado-Carvajal A, Kim M, Akeju O, Grmek G, Chane C, Murphy J, Schrepf A, Harris RE, Kwon YM, Bedair H, Siliski J, Chen AF, Melnic C, Jarraya M, Napadow V, Veronese M, Maccioni L, Edwards RR, Efthimiou N, Mohammadian M, Luo E, Pollak LE, Catana C, Toschi N, Loggia ML
Brain inflammation and its predictive value for post-operative pain in total knee arthroplasty patients. Brain Behav Immun. 2025 Aug; 128:703-712.
Brain inflammation and its predictive value for post-operative pain in total knee arthroplasty patients.
Tommasin S, Giannì C, Treaba CA, Herranz E, Barletta V, Loggia ML, Pantano P, Mainero C
Multiple sclerosis and related disorders
The association between white matter chronic inflammation and degeneration in multiple sclerosis: A combined 11C-PBR28 PET-MRI study. Mult Scler Relat Disord. 2025 Apr; 96:106350.
The association between white matter chronic inflammation and degeneration in multiple sclerosis: A combined 11C-PBR28 PET-MRI study.
Schuman-Olivier Z, Marin F, Kinder LD, Datko M, Round K, Tohyama S, Garcia RG, Hirschtick RL, Edwards RR, Wells RE, Cheng HT, Barbieri R, Hadjikhani N, Loggia ML, Kaptchuk TJ, Houle TT, Rosen BR, Napadow V
Evaluating brain mechanisms of combined vagus nerve stimulation and mindfulness training for migraine: A randomized 2 × 2 factorial clinical trial protocol. Contemp Clin Trials. 2025 Jul; 154:107947.
Evaluating brain mechanisms of combined vagus nerve stimulation and mindfulness training for migraine: A randomized 2 × 2 factorial clinical trial protocol.
Loggia ML, Berna C, Kim J, Cahalan CM, Gollub RL, Wasan AD, Harris RE, Edwards RR, Napadow V
Disrupted brain circuitry for pain-related reward/punishment in fibromyalgia. Arthritis Rheumatol. 2014 Jan; 66(1):203-12.
Disrupted brain circuitry for pain-related reward/punishment in fibromyalgia.
Efthimiou N, Fu JF, Mohammadian M, Tseng CJ, Scipioni M, Zhou IY, Zürcher NR, Mandeville JB, Price JC, Loggia ML, Catana C
medRxiv : the preprint server for health sciences
Tangible advantages of multi-stage brain motion compensation for PET imaging demonstrated in multiple studies. medRxiv. 2025 Sep 19.
Tangible advantages of multi-stage brain motion compensation for PET imaging demonstrated in multiple studies.
Amygdala perfusion is predicted by its functional connectivity with the ventromedial prefrontal cortex and negative affect. PLoS One. 2014; 9(5):e97466.
Amygdala perfusion is predicted by its functional connectivity with the ventromedial prefrontal cortex and negative affect.
Loggia ML, Edwards RR, Harris RE, Napadow V
Reply: To PMID 24449585. Arthritis Rheumatol. 2014 Jun; 66(6):1684-5.
Loggia ML, Brugarolas P, Catana C, Hooker JM
How the next 50 years of positron emission tomography can transform our understanding of chronic pain. Pain. 2025 Nov 01; 166(11S):S71-S74.
How the next 50 years of positron emission tomography can transform our understanding of chronic pain.
Sandström A, Kim M, Weerasekera A, Lin Y, Castro-Blanco K, Tandon A, Murphy J, Byrne K, Alshelh Z, Torrado-Carvajal A, Goodin BR, Ahern R, Marx C, Kilts J, Gandhi RT, Napadow V, Edwards RR, Pollak L, Mukerji SS, Loggia ML, Ratai EM
Brain levels of the neurotransmitter ?-aminobutyric acid are reduced in people with HIV-related neuropathic pain. Pain. 2026 Jan 01; 167(1):e8-e17.
Brain levels of the neurotransmitter ?-aminobutyric acid are reduced in people with HIV-related neuropathic pain.
Ferrante M, Inglese M, Brusaferri L, Toschi N, Loggia ML
Generation of synthetic TSPO PET maps from structural MRI images. Front Neuroinform. 2025; 19:1633273.
Generation of synthetic TSPO PET maps from structural MRI images.
Hanuka S, Tamari N, Eldar E, Loggia ML, Horesh D, Admon R
Predicting daily pain fluctuations in fibromyalgia: The role of mental distress and sleep heart-rate. J Pain. 2025 Dec; 37:105572.
Predicting daily pain fluctuations in fibromyalgia: The role of mental distress and sleep heart-rate.
Brusaferri L, Whitehead AC, Maccioni L, Alshelh Z, Veronese M, Turkheimer FE, Toschi N, Ferrante M, Inglese M, Catana C, Gilman J, Grisan E, Loggia ML
Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference
Advancing Generalisable Neural Network-Based PET Quantification: A Multicenter [11C]PBR28 study. Annu Int Conf IEEE Eng Med Biol Soc. 2025 Jul; 2025:1-5.
Advancing Generalisable Neural Network-Based PET Quantification: A Multicenter [11C]PBR28 study.
A novel blood-free analytical framework for the quantification of neuroinflammatory load from TSPO PET imaging. J Cereb Blood Flow Metab. 2025 Dec; 45(12):2283-2300.
A novel blood-free analytical framework for the quantification of neuroinflammatory load from TSPO PET imaging.
Barzon L, Maccioni L, Mellana MC, Schubert JJ, Brusaferri L, Cousins O, Rosenzweig I, Mizuno Y, Marques TR, Harrison NA, Fryer T, Bullmore ET, Mondelli V, Pariante C, Sharp D, Scott G, Pereira JB, Howes O, Sossi V, Bodini B, Stankoff B, Loggia ML, Turkheimer FE, Veronese M
Network-based disease fingerprinting with neuroinflammation PET imaging. Res Sq. 2025 Oct 21.
Network-based disease fingerprinting with neuroinflammation PET imaging.
Dolman AJ, Loggia ML, Edwards RR, Gollub RL, Kong J, Napadow V, Wasan AD
Phenotype matters: the absence of a positive association between cortical thinning and chronic low back pain when controlling for salient clinical variables. Clin J Pain. 2014 Oct; 30(10):839-45.
Phenotype matters: the absence of a positive association between cortical thinning and chronic low back pain when controlling for salient clinical variables.
Akeju O, Loggia ML, Catana C, Pavone KJ, Vazquez R, Rhee J, Contreras Ramirez V, Chonde DB, Izquierdo-Garcia D, Arabasz G, Hsu S, Habeeb K, Hooker JM, Napadow V, Brown EN, Purdon PL
Disruption of thalamic functional connectivity is a neural correlate of dexmedetomidine-induced unconsciousness. Elife. 2014 Nov 28; 3:e04499.
Disruption of thalamic functional connectivity is a neural correlate of dexmedetomidine-induced unconsciousness.
Loggia ML, Chonde DB, Akeju O, Arabasz G, Catana C, Edwards RR, Hill E, Hsu S, Izquierdo-Garcia D, Ji RR, Riley M, Wasan AD, Zürcher NR, Albrecht DS, Vangel MG, Rosen BR, Napadow V, Hooker JM
Evidence for brain glial activation in chronic pain patients. Brain. 2015 Mar; 138(Pt 3):604-15.
Evidence for brain glial activation in chronic pain patients.
Zürcher NR, Loggia ML, Lawson R, Chonde DB, Izquierdo-Garcia D, Yasek JE, Akeju O, Catana C, Rosen BR, Cudkowicz ME, Hooker JM, Atassi N
Increased in vivo glial activation in patients with amyotrophic lateral sclerosis: assessed with [(11)C]-PBR28. Neuroimage Clin. 2015; 7:409-14.
Increased in vivo glial activation in patients with amyotrophic lateral sclerosis: assessed with [(11)C]-PBR28.
Desbordes G, Li A, Loggia ML, Kim J, Schalock PC, Lerner E, Tran TN, Ring J, Rosen BR, Kaptchuk TJ, Pfab F, Napadow V
Evoked itch perception is associated with changes in functional brain connectivity. Neuroimage Clin. 2015; 7:213-21.
Evoked itch perception is associated with changes in functional brain connectivity.
Loggia ML, Berna C, Kim J, Cahalan CM, Martel MO, Gollub RL, Wasan AD, Napadow V, Edwards RR
The lateral prefrontal cortex mediates the hyperalgesic effects of negative cognitions in chronic pain patients. J Pain. 2015 Aug; 16(8):692-9.
The lateral prefrontal cortex mediates the hyperalgesic effects of negative cognitions in chronic pain patients.
Kim H, Kim J, Loggia ML, Cahalan C, Garcia RG, Vangel MG, Wasan AD, Edwards RR, Napadow V
Fibromyalgia is characterized by altered frontal and cerebellar structural covariance brain networks. Neuroimage Clin. 2015; 7:667-77.
Fibromyalgia is characterized by altered frontal and cerebellar structural covariance brain networks.
Kim J, Loggia ML, Cahalan CM, Harris RE, Beissner F, Garcia RG, Kim H, Wasan AD, Edwards RR, Napadow V
The somatosensory link in fibromyalgia: functional connectivity of the primary somatosensory cortex is altered by sustained pain and is associated with clinical/autonomic dysfunction. Arthritis Rheumatol. 2015 May; 67(5):1395-1405.
The somatosensory link in fibromyalgia: functional connectivity of the primary somatosensory cortex is altered by sustained pain and is associated with clinical/autonomic dysfunction.
Lai TH, Protsenko E, Cheng YC, Loggia ML, Coppola G, Chen WT
Neural Plasticity in Common Forms of Chronic Headaches. Neural Plast. 2015; 2015:205985.
Neural Plasticity in Common Forms of Chronic Headaches.
Napadow V, Li A, Loggia ML, Kim J, Mawla I, Desbordes G, Schalock PC, Lerner EA, Tran TN, Ring J, Rosen BR, Kaptchuk TJ, Pfab F
The imagined itch: brain circuitry supporting nocebo-induced itch in atopic dermatitis patients. Allergy. 2015 Nov; 70(11):1485-92.
The imagined itch: brain circuitry supporting nocebo-induced itch in atopic dermatitis patients.
Ibinson JW, Vogt KM, Taylor KB, Dua SB, Becker CJ, Loggia M, Wasan AD
Optimizing and Interpreting Insular Functional Connectivity Maps Obtained During Acute Experimental Pain: The Effects of Global Signal and Task Paradigm Regression. Brain Connect. 2015 Dec; 5(10):649-57.
Optimizing and Interpreting Insular Functional Connectivity Maps Obtained During Acute Experimental Pain: The Effects of Global Signal and Task Paradigm Regression.
In Vivo Imaging of Human Neuroinflammation. ACS Chem Neurosci. 2016 Apr 20; 7(4):470-83.
In Vivo Imaging of Human Neuroinflammation.
The Role of Neuroimmune Activation in Chronic Pain and Negative Affect
The Role of Brain Glial Activation in knee Ostoarthritis
In-vivo imaging of spinal and brain glial activation in low back pain patients
Lazaridou A, Kim J, Cahalan CM, Loggia ML, Franceschelli O, Berna C, Schur P, Napadow V, Edwards RR
Effects of Cognitive-Behavioral Therapy (CBT) on Brain Connectivity Supporting Catastrophizing in Fibromyalgia. Clin J Pain. 2017 03; 33(3):215-221.
Effects of Cognitive-Behavioral Therapy (CBT) on Brain Connectivity Supporting Catastrophizing in Fibromyalgia.
Alshikho MJ, Zürcher NR, Loggia ML, Cernasov P, Chonde DB, Izquierdo Garcia D, Yasek JE, Akeju O, Catana C, Rosen BR, Cudkowicz ME, Hooker JM, Atassi N
Glial activation colocalizes with structural abnormalities in amyotrophic lateral sclerosis. Neurology. 2016 Dec 13; 87(24):2554-2561.
Glial activation colocalizes with structural abnormalities in amyotrophic lateral sclerosis.
Herranz E, Giannì C, Louapre C, Treaba CA, Govindarajan ST, Ouellette R, Loggia ML, Sloane JA, Madigan N, Izquierdo-Garcia D, Ward N, Mangeat G, Granberg T, Klawiter EC, Catana C, Hooker JM, Taylor N, Ionete C, Kinkel RP, Mainero C
Neuroinflammatory component of gray matter pathology in multiple sclerosis. Ann Neurol. 2016 Nov; 80(5):776-790.
Neuroinflammatory component of gray matter pathology in multiple sclerosis.
Lee J, Lin RL, Garcia RG, Kim J, Kim H, Loggia ML, Mawla I, Wasan AD, Edwards RR, Rosen BR, Hadjikhani N, Napadow V
Cephalalgia : an international journal of headache
Reduced insula habituation associated with amplification of trigeminal brainstem input in migraine. Cephalalgia. 2017 Oct; 37(11):1026-1038.
Reduced insula habituation associated with amplification of trigeminal brainstem input in migraine.
Herranz E, Hooker JM, Izquierdo-Garcia D, Loggia ML, Mainero C
Hashmi JA, Loggia ML, Khan S, Gao L, Kim J, Napadow V, Brown EN, Akeju O
Dexmedetomidine Disrupts the Local and Global Efficiencies of Large-scale Brain Networks. Anesthesiology. 2017 Mar; 126(3):419-430.
Dexmedetomidine Disrupts the Local and Global Efficiencies of Large-scale Brain Networks.
Mawla I, Loggia M, Schmithorst V, Ortiz A, Gerber J, Protsenko E, Lee J, Kim J, Kim H, Berna C, Kaptchuk T, Kong J, Gollub R, Rosen B, Edwards R, Wasan A, Napadow V
The journal of pain : official journal of the American Pain Society
(336) Investigating the neural circuitry supporting clinical pain perception in chronic low back pain - the importance of cardiorespiratory artifact correction with arterial spin labeling fMRI. J Pain. 2016 Apr; 17(4S):S59-S60.
(336) Investigating the neural circuitry supporting clinical pain perception in chronic low back pain - the importance of cardiorespiratory artifact correction with arterial spin labeling fMRI.
Garcia R, Lin R, Lee J, Loggia M, Kim J, Kim H, Wasan A, Edwards R, Hadjikhani N, Napadow V
(395) Brainstem activity and connectivity is modulated by respiratory-gated auricular vagus afferent nerve stimulation (RAVANS) in migraine patients - an fMRI study. J Pain. 2016 Apr; 17(4S):S73-S74.
(395) Brainstem activity and connectivity is modulated by respiratory-gated auricular vagus afferent nerve stimulation (RAVANS) in migraine patients - an fMRI study.
Schreiber KL, Loggia ML, Kim J, Cahalan CM, Napadow V, Edwards RR
Painful After-Sensations in Fibromyalgia are Linked to Catastrophizing and Differences in Brain Response in the Medial Temporal Lobe. J Pain. 2017 07; 18(7):855-867.
Painful After-Sensations in Fibromyalgia are Linked to Catastrophizing and Differences in Brain Response in the Medial Temporal Lobe.
Loggia ML, Schweinhardt P, Villemure C, Bushnell MC
Effects of psychological state on pain perception in the dental environment. J Can Dent Assoc. 2008 Sep; 74(7):651-6.
Effects of psychological state on pain perception in the dental environment.
Song AH, Kucyi A, Napadow V, Brown EN, Loggia ML, Akeju O
Pharmacological Modulation of Noradrenergic Arousal Circuitry Disrupts Functional Connectivity of the Locus Ceruleus in Humans. J Neurosci. 2017 07 19; 37(29):6938-6945.
Pharmacological Modulation of Noradrenergic Arousal Circuitry Disrupts Functional Connectivity of the Locus Ceruleus in Humans.
Nijs J, Loggia ML, Polli A, Moens M, Huysmans E, Goudman L, Meeus M, Vanderweeën L, Ickmans K, Clauw D
Sleep disturbances and severe stress as glial activators: key targets for treating central sensitization in chronic pain patients? Expert Opin Ther Targets. 2017 08; 21(8):817-826.
Sleep disturbances and severe stress as glial activators: key targets for treating central sensitization in chronic pain patients?
Albrecht DS, Normandin MD, Shcherbinin S, Wooten DW, Schwarz AJ, Zürcher NR, Barth VN, Guehl NJ, Akeju O, Atassi N, Veronese M, Turkheimer F, Hooker JM, Loggia ML
Pseudoreference Regions for Glial Imaging with 11C-PBR28: Investigation in 2 Clinical Cohorts. J Nucl Med. 2018 01; 59(1):107-114.
Pseudoreference Regions for Glial Imaging with 11C-PBR28: Investigation in 2 Clinical Cohorts.
Loggia ML, Jensen K, Gollub RL, Wasan AD, Edwards RR, Kong J
The catechol-O-methyltransferase (COMT) val158met polymorphism affects brain responses to repeated painful stimuli. PLoS One. 2011; 6(11):e27764.
The catechol-O-methyltransferase (COMT) val158met polymorphism affects brain responses to repeated painful stimuli.
Experimentally induced mood changes preferentially affect pain unpleasantness. J Pain. 2008 Sep; 9(9):784-91.
Experimentally induced mood changes preferentially affect pain unpleasantness.
Ran C, Albrecht DS, Bredella MA, Yang J, Yang J, Liang SH, Cypess AM, Loggia ML, Atassi N, Moore A
PET Imaging of Human Brown Adipose Tissue with the TSPO Tracer [11C]PBR28. Mol Imaging Biol. 2018 04; 20(2):188-193.
PET Imaging of Human Brown Adipose Tissue with the TSPO Tracer [11C]PBR28.
Paganoni S, Alshikho MJ, Zürcher NR, Cernasov P, Babu S, Loggia ML, Chan J, Chonde DB, Garcia DI, Catana C, Mainero C, Rosen BR, Cudkowicz ME, Hooker JM, Atassi N
Imaging of glia activation in people with primary lateral sclerosis. Neuroimage Clin. 2018; 17:347-353.
Imaging of glia activation in people with primary lateral sclerosis.
Empathy hurts: compassion for another increases both sensory and affective components of pain perception. Pain. 2008 May; 136(1-2):168-76.
Empathy hurts: compassion for another increases both sensory and affective components of pain perception.
Autonomic responses to heat pain: Heart rate, skin conductance, and their relation to verbal ratings and stimulus intensity. Pain. 2011 Mar; 152(3):592-598.
Autonomic responses to heat pain: Heart rate, skin conductance, and their relation to verbal ratings and stimulus intensity.
Loggia ML, Bushnell MC, Tétreault M, Thiffault I, Bhérer C, Mohammed NK, Kuchinad AA, Laferrière A, Dicaire MJ, Loisel L, Mogil JS, Brais B
Carriers of recessive WNK1/HSN2 mutations for hereditary sensory and autonomic neuropathy type 2 (HSAN2) are more sensitive to thermal stimuli. J Neurosci. 2009 Feb 18; 29(7):2162-6.
Carriers of recessive WNK1/HSN2 mutations for hereditary sensory and autonomic neuropathy type 2 (HSAN2) are more sensitive to thermal stimuli.
Napadow V, Li A, Loggia ML, Kim J, Schalock PC, Lerner E, Tran TN, Ring J, Rosen BR, Kaptchuk TJ, Pfab F
The brain circuitry mediating antipruritic effects of acupuncture. Cereb Cortex. 2014 Apr; 24(4):873-82.
The brain circuitry mediating antipruritic effects of acupuncture.