Gordon, Leslie
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first name: Leslie
last name: Gordon
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coauthor of: Gerhard-Herman, Marie
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full name: Leslie Beth Gordon, M.D.,Ph.D.
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Authorship 1049850
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linked author: Gordon, Leslie
linked information resource: Cardiac Abnormalities in Patients With Hutchinson-Gilford Progeria Syndrome.

Authorship 1052568
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author rank in publication: 4
linked author: Gordon, Leslie
linked information resource: Microbiome at sites of gingival recession in children with Hutchinson-Gilford progeria syndrome.

Microbiome at sites of gingival recession in children with Hutchinson-Gilford progeria syndrome.
PubMed Identifier: 29520806
author list: Bassir SH, Chase I, Paster BJ, Gordon LB, Kleinman ME, Kieran MW, Kim DM, Sonis A
published in: Journal of periodontology
information resource reference: Microbiome at sites of gingival recession in children with Hutchinson-Gilford progeria syndrome. J Periodontol. 2018 06; 89(6):635-644.
journal title abbreviation: J Periodontol
publication date: 2018-06-01T00:00:00
year: 2018
type: Academic Article
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Authorship 1054696
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linked author: Gordon, Leslie
linked information resource: Everolimus rescues multiple cellular defects in laminopathy-patient fibroblasts.

Authorship 1055511
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author rank in publication: 7
linked author: Gordon, Leslie
linked information resource: Otologic and audiologic manifestations of Hutchinson-Gilford progeria syndrome.

Authorship 1054663
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linked information resource: The cell nucleus and aging: tantalizing clues and hopeful promises.

Everolimus rescues multiple cellular defects in laminopathy-patient fibroblasts.
PubMed Identifier: 29581305
author list: DuBose AJ, Lichtenstein ST, Petrash NM, Erdos MR, Gordon LB, Collins FS
published in: Proceedings of the National Academy of Sciences of the United States of America
information resource reference: Everolimus rescues multiple cellular defects in laminopathy-patient fibroblasts. Proc Natl Acad Sci U S A. 2018 04 17; 115(16):4206-4211.
journal title abbreviation: Proc Natl Acad Sci U S A
publication date: 2018-03-26T00:00:00
year: 2018
type: Academic Article
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Otologic and audiologic manifestations of Hutchinson-Gilford progeria syndrome.
PubMed Identifier: 21898437
author list: Guardiani E, Zalewski C, Brewer C, Merideth M, Introne W, Smith AC, Gordon L, Gahl W, Kim HJ
published in: The Laryngoscope
information resource reference: Otologic and audiologic manifestations of Hutchinson-Gilford progeria syndrome. Laryngoscope. 2011 Oct; 121(10):2250-5.
journal title abbreviation: Laryngoscope
publication date: 2011-09-06T00:00:00
year: 2011
type: Academic Article
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The cell nucleus and aging: tantalizing clues and hopeful promises.
PubMed Identifier: 16277559
author list: Scaffidi P, Gordon L, Misteli T
published in: PLoS biology
information resource reference: The cell nucleus and aging: tantalizing clues and hopeful promises. PLoS Biol. 2005 Nov; 3(11):e395.
journal title abbreviation: PLoS Biol
publication date: 2005-11-15T00:00:00
year: 2005
type: Academic Article
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Recurrent de novo point mutations in lamin A cause Hutchinson-Gilford progeria syndrome.
PubMed Identifier: 12714972
author list: Eriksson M, Brown WT, Gordon LB, Glynn MW, Singer J, Scott L, Erdos MR, Robbins CM, Moses TY, Berglund P, Dutra A, Pak E, Durkin S, Csoka AB, Boehnke M, Glover TW, Collins FS
published in: Nature
information resource reference: Recurrent de novo point mutations in lamin A cause Hutchinson-Gilford progeria syndrome. Nature. 2003 May 15; 423(6937):293-8.
journal title abbreviation: Nature
publication date: 2003-04-25T00:00:00
year: 2003
type: Academic Article
type: Article
type: Document
type: Information Resource

Defective lamin A-Rb signaling in Hutchinson-Gilford Progeria Syndrome and reversal by farnesyltransferase inhibition.
PubMed Identifier: 20559568
author list: Marji J, O'Donoghue SI, McClintock D, Satagopam VP, Schneider R, Ratner D, Worman HJ, Gordon LB, Djabali K
published in: PloS one
information resource reference: Defective lamin A-Rb signaling in Hutchinson-Gilford Progeria Syndrome and reversal by farnesyltransferase inhibition. PLoS One. 2010 Jun 15; 5(6):e11132.
journal title abbreviation: PLoS One
publication date: 2010-06-15T00:00:00
year: 2010
type: Academic Article
type: Article
type: Document
type: Information Resource

Mechanisms of premature vascular aging in children with Hutchinson-Gilford progeria syndrome.
PubMed Identifier: 22083160
author list: Gerhard-Herman M, Smoot LB, Wake N, Kieran MW, Kleinman ME, Miller DT, Schwartzman A, Giobbie-Hurder A, Neuberg D, Gordon LB
published in: Hypertension (Dallas, Tex. : 1979)
information resource reference: Mechanisms of premature vascular aging in children with Hutchinson-Gilford progeria syndrome. Hypertension. 2012 Jan; 59(1):92-7.
journal title abbreviation: Hypertension
publication date: 2011-11-14T00:00:00
year: 2011
type: Academic Article
type: Article
type: Document
type: Information Resource

Naïve adult stem cells from patients with Hutchinson-Gilford progeria syndrome express low levels of progerin in vivo.
PubMed Identifier: 23213444
author list: Wenzel V, Roedl D, Gabriel D, Gordon LB, Herlyn M, Schneider R, Ring J, Djabali K
published in: Biology open
information resource reference: Naïve adult stem cells from patients with Hutchinson-Gilford progeria syndrome express low levels of progerin in vivo. Biol Open. 2012 Jun 15; 1(6):516-26.
journal title abbreviation: Biol Open
publication date: 2012-04-16T00:00:00
year: 2012
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Authorship 1062493
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linked information resource: Association of Lonafarnib Treatment vs No Treatment With Mortality Rate in Patients With Hutchinson-Gilford Progeria Syndrome.

Association of Lonafarnib Treatment vs No Treatment With Mortality Rate in Patients With Hutchinson-Gilford Progeria Syndrome.
PubMed Identifier: 29710166
author list: Gordon LB, Shappell H, Massaro J, D'Agostino RB, Brazier J, Campbell SE, Kleinman ME, Kieran MW
published in: JAMA
information resource reference: Association of Lonafarnib Treatment vs No Treatment With Mortality Rate in Patients With Hutchinson-Gilford Progeria Syndrome. JAMA. 2018 04 24; 319(16):1687-1695.
journal title abbreviation: JAMA
publication date: 2018-04-24T00:00:00
year: 2018
type: Academic Article
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Hutchinson-Gilford progeria mutant lamin A primarily targets human vascular cells as detected by an anti-Lamin A G608G antibody.
PubMed Identifier: 16461887
author list: McClintock D, Gordon LB, Djabali K
published in: Proceedings of the National Academy of Sciences of the United States of America
information resource reference: Hutchinson-Gilford progeria mutant lamin A primarily targets human vascular cells as detected by an anti-Lamin A G608G antibody. Proc Natl Acad Sci U S A. 2006 Feb 14; 103(7):2154-9.
journal title abbreviation: Proc Natl Acad Sci U S A
publication date: 2006-02-06T00:00:00
year: 2006
type: Academic Article
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Hyaluronan is not elevated in urine or serum in Hutchinson-Gilford Progeria Syndrome.
PubMed Identifier: 12728312
author list: Gordon LB, Harten IA, Calabro A, Sugumaran G, Csoka AB, Brown WT, Hascall V, Toole BP
published in: Human genetics
information resource reference: Hyaluronan is not elevated in urine or serum in Hutchinson-Gilford Progeria Syndrome. Hum Genet. 2003 Jul; 113(2):178-87.
journal title abbreviation: Hum Genet
publication date: 2003-05-01T00:00:00
year: 2003
type: Academic Article
type: Article
type: Document
type: Information Resource

Age-dependent loss of MMP-3 in Hutchinson-Gilford progeria syndrome.
PubMed Identifier: 21852285
author list: Harten IA, Zahr RS, Lemire JM, Machan JT, Moses MA, Doiron RJ, Curatolo AS, Rothman FG, Wight TN, Toole BP, Gordon LB
published in: The journals of gerontology. Series A, Biological sciences and medical sciences
information resource reference: Age-dependent loss of MMP-3 in Hutchinson-Gilford progeria syndrome. J Gerontol A Biol Sci Med Sci. 2011 Nov; 66(11):1201-7.
journal title abbreviation: J Gerontol A Biol Sci Med Sci
publication date: 2011-08-17T00:00:00
year: 2011
type: Academic Article
type: Article
type: Document
type: Information Resource

Highlights of the 2007 Progeria Research Foundation scientific workshop: progress in translational science.
PubMed Identifier: 18772465
author list: Gordon LB, Harling-Berg CJ, Rothman FG
published in: The journals of gerontology. Series A, Biological sciences and medical sciences
information resource reference: Highlights of the 2007 Progeria Research Foundation scientific workshop: progress in translational science. J Gerontol A Biol Sci Med Sci. 2008 Aug; 63(8):777-87.
journal title abbreviation: J Gerontol A Biol Sci Med Sci
publication date: 2008-08-01T00:00:00
year: 2008
type: Academic Article
type: Article
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type: Information Resource

Phenotype and course of Hutchinson-Gilford progeria syndrome.
PubMed Identifier: 18256394
author list: Merideth MA, Gordon LB, Clauss S, Sachdev V, Smith AC, Perry MB, Brewer CC, Zalewski C, Kim HJ, Solomon B, Brooks BP, Gerber LH, Turner ML, Domingo DL, Hart TC, Graf J, Reynolds JC, Gropman A, Yanovski JA, Gerhard-Herman M, Collins FS, Nabel EG, Cannon RO, Gahl WA, Introne WJ
published in: The New England journal of medicine
information resource reference: Phenotype and course of Hutchinson-Gilford progeria syndrome. N Engl J Med. 2008 Feb 07; 358(6):592-604.
journal title abbreviation: N Engl J Med
publication date: 2008-02-07T00:00:00
year: 2008
type: Academic Article
type: Article
type: Document
type: Information Resource

Craniofacial abnormalities in Hutchinson-Gilford progeria syndrome.
PubMed Identifier: 22460337
author list: Ullrich NJ, Silvera VM, Campbell SE, Gordon LB
published in: AJNR. American journal of neuroradiology
information resource reference: Craniofacial abnormalities in Hutchinson-Gilford progeria syndrome. AJNR Am J Neuroradiol. 2012 Sep; 33(8):1512-8.
journal title abbreviation: AJNR Am J Neuroradiol
publication date: 2012-03-29T00:00:00
year: 2012
type: Academic Article
type: Article
type: Document
type: Information Resource

A prospective study of radiographic manifestations in Hutchinson-Gilford progeria syndrome.
PubMed Identifier: 22752073
author list: Cleveland RH, Gordon LB, Kleinman ME, Miller DT, Gordon CM, Snyder BD, Nazarian A, Giobbie-Hurder A, Neuberg D, Kieran MW
published in: Pediatric radiology
information resource reference: A prospective study of radiographic manifestations in Hutchinson-Gilford progeria syndrome. Pediatr Radiol. 2012 Sep; 42(9):1089-98.
journal title abbreviation: Pediatr Radiol
publication date: 2012-07-01T00:00:00
year: 2012
type: Academic Article
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type: Document
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Authorship 1114550
type: Authorship
author rank in publication: 20
linked author: Gordon, Leslie
linked information resource: Analyses of LMNA-negative juvenile progeroid cases confirms biallelic POLR3A mutations in Wiedemann-Rautenstrauch-like syndrome and expands the phenotypic spectrum of PYCR1 mutations.

Analyses of LMNA-negative juvenile progeroid cases confirms biallelic POLR3A mutations in Wiedemann-Rautenstrauch-like syndrome and expands the phenotypic spectrum of PYCR1 mutations.
PubMed Identifier: 30450527
author list: Lessel D, Ozel AB, Campbell SE, Saadi A, Arlt MF, McSweeney KM, Plaiasu V, Szakszon K, Szollos A, Rusu C, Rojas AJ, Lopez-Valdez J, Thiele H, Nürnberg P, Nickerson DA, Bamshad MJ, Li JZ, Kubisch C, Glover TW, Gordon LB
published in: Human genetics
information resource reference: Analyses of LMNA-negative juvenile progeroid cases confirms biallelic POLR3A mutations in Wiedemann-Rautenstrauch-like syndrome and expands the phenotypic spectrum of PYCR1 mutations. Hum Genet. 2018 Dec; 137(11-12):921-939.
journal title abbreviation: Hum Genet
publication date: 2018-11-19T00:00:00
year: 2018
type: Academic Article
type: Article
type: Document
type: Information Resource

The Progeria Research Foundation 9th International Scientific Workshop Many Pathways, One Goal
end date: 2019-08-31
principal investigator name: GORDON, LESLIE B
start date: 2018-09-04
type: Grant
sponsor award id: R13AG062031

Principal Investigator
type: Researcher Role
researcher role of: Gordon, Leslie
contributes to: The Progeria Research Foundation 9th International Scientific Workshop Many Pathways, One Goal

Progeria
MeSH DescriptorUI: D011371
MeSH semantic group name: Disorders
number of authors: 46
number of publications: 185
uniqueness weight: 0.837937
type: Concept

Hypothermia
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MeSH semantic group name: Disorders
number of authors: 142
number of publications: 185
uniqueness weight: 0.857455
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Lamin Type A
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MeSH semantic group name: Chemicals & Drugs
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number of publications: 209
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Piperidines
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MeSH semantic group name: Chemicals & Drugs
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Pyridines
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Anaesthesia
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Medicine
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Neurology
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Orthopedic Surgery
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Pediatrics
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Surgery
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Cardiology
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type: Organization

Endocrinology
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Beth Israel Deaconess Medical Center
type: Organization

Brigham and Women's Hospital
type: Organization

Boston Children's Hospital
type: Organization

Ullrich, Nicole
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Kleinman, Monica
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Mohammad, Shoaib
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Gerhard-Herman, Marie
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Greco, Christine
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Nazarian, Ara
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Blum, Richard
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Moses, Marsha
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Daaboul, Dima
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Navedo-Rivera, Andres
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Prakash, Ashwin
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person in primary position: Associate Professor of Pediatrics
type: Agent
type: Person
preferred title: Associate Professor of Pediatrics

Authorship 139635
type: Authorship
author rank in publication: 5
linked author: Gordon, Leslie
linked information resource: The mutant form of lamin A that causes Hutchinson-Gilford progeria is a biomarker of cellular aging in human skin.

Progerin as a Biomarker for Hutchinson-Gilford Progeria Syndrome
end date: 2021-08-31
principal investigator name: GORDON, LESLIE B
start date: 2019-09-01
type: Grant
sponsor award id: U01FD006886

Principal Investigator
type: Researcher Role
researcher role of: Gordon, Leslie
contributes to: Progerin as a Biomarker for Hutchinson-Gilford Progeria Syndrome

Authorship 131067
type: Authorship
author rank in publication: 1
linked author: Gordon, Leslie
linked information resource: Ovalbumin is more immunogenic when introduced into brain or cerebrospinal fluid than into extracerebral sites.

Authorship 1232008
type: Authorship
author rank in publication: 3
linked author: Gordon, Leslie
linked information resource: Skeletal maturation and long-bone growth patterns of patients with progeria: a retrospective study.

Skeletal maturation and long-bone growth patterns of patients with progeria: a retrospective study.
PubMed Identifier: 32119840
author list: Tsai A, Johnston PR, Gordon LB, Walters M, Kleinman M, Laor T
published in: The Lancet. Child & adolescent health
information resource reference: Skeletal maturation and long-bone growth patterns of patients with progeria: a retrospective study. Lancet Child Adolesc Health. 2020 04; 4(4):281-289.
journal title abbreviation: Lancet Child Adolesc Health
publication date: 2020-02-28T00:00:00
year: 2020
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 151660
type: Authorship
author rank in publication: 2
linked author: Gordon, Leslie
linked information resource: Hutchinson-Gilford progeria mutant lamin A primarily targets human vascular cells as detected by an anti-Lamin A G608G antibody.

Authorship 1316767
type: Authorship
author rank in publication: 17
linked author: Gordon, Leslie
linked information resource: In vivo base editing rescues Hutchinson-Gilford progeria syndrome in mice.

In vivo base editing rescues Hutchinson-Gilford progeria syndrome in mice.
PubMed Identifier: 33408413
author list: Koblan LW, Erdos MR, Wilson C, Cabral WA, Levy JM, Xiong ZM, Tavarez UL, Davison LM, Gete YG, Mao X, Newby GA, Doherty SP, Narisu N, Sheng Q, Krilow C, Lin CY, Gordon LB, Cao K, Collins FS, Brown JD, Liu DR
published in: Nature
information resource reference: In vivo base editing rescues Hutchinson-Gilford progeria syndrome in mice. Nature. 2021 01; 589(7843):608-614.
journal title abbreviation: Nature
publication date: 2021-01-06T00:00:00
year: 2021
type: Academic Article
type: Article
type: Document
type: Information Resource

The Progeria Research Foundation 10th International Scientific Workshop, Researching Possibilities, ExTENding Lives
end date: 2021-12-31
principal investigator name: GORDON, LESLIE B
start date: 2021-01-15
type: Grant
sponsor award id: R13AG071212

Principal Investigator
type: Researcher Role
researcher role of: Gordon, Leslie
contributes to: The Progeria Research Foundation 10th International Scientific Workshop, Researching Possibilities, ExTENding Lives

Authorship 1337408
type: Authorship
author rank in publication: 6
linked author: Gordon, Leslie
linked information resource: Systematic screening identifies therapeutic antisense oligonucleotides for Hutchinson-Gilford progeria syndrome.

Authorship 1337308
type: Authorship
author rank in publication: 14
linked author: Gordon, Leslie
linked information resource: A targeted antisense therapeutic approach for Hutchinson-Gilford progeria syndrome.

A targeted antisense therapeutic approach for Hutchinson-Gilford progeria syndrome.
PubMed Identifier: 33707773
author list: Erdos MR, Cabral WA, Tavarez UL, Cao K, Gvozdenovic-Jeremic J, Narisu N, Zerfas PM, Crumley S, Boku Y, Hanson G, Mourich DV, Kole R, Eckhaus MA, Gordon LB, Collins FS
published in: Nature medicine
information resource reference: A targeted antisense therapeutic approach for Hutchinson-Gilford progeria syndrome. Nat Med. 2021 03; 27(3):536-545.
journal title abbreviation: Nat Med
publication date: 2021-03-11T00:00:00
year: 2021
type: Academic Article
type: Article
type: Document
type: Information Resource

Systematic screening identifies therapeutic antisense oligonucleotides for Hutchinson-Gilford progeria syndrome.
PubMed Identifier: 33707772
author list: Puttaraju M, Jackson M, Klein S, Shilo A, Bennett CF, Gordon L, Rigo F, Misteli T
published in: Nature medicine
information resource reference: Systematic screening identifies therapeutic antisense oligonucleotides for Hutchinson-Gilford progeria syndrome. Nat Med. 2021 03; 27(3):526-535.
journal title abbreviation: Nat Med
publication date: 2021-03-11T00:00:00
year: 2021
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1339604
type: Authorship
author rank in publication: 1
linked author: Gordon, Leslie
linked information resource: The progeria research foundation 10th international scientific workshop; researching possibilities, ExTENding lives - webinar version scientific summary.

The progeria research foundation 10th international scientific workshop; researching possibilities, ExTENding lives - webinar version scientific summary.
PubMed Identifier: 33735109
author list: Gordon LB, Tuminelli K, Andrés V, Campisi J, Kieran MW, Doucette L, Gordon AS
published in: Aging
information resource reference: The progeria research foundation 10th international scientific workshop; researching possibilities, ExTENding lives - webinar version scientific summary. Aging (Albany NY). 2021 03 17; 13(6):9143-9151.
journal title abbreviation: Aging (Albany NY)
publication date: 2021-03-17T00:00:00
year: 2021
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1360982
type: Authorship
author rank in publication: 6
linked author: Gordon, Leslie
linked information resource: Author Correction: Systematic screening identifies therapeutic antisense oligonucleotides for Hutchinson-Gilford progeria syndrome.

Author Correction: Systematic screening identifies therapeutic antisense oligonucleotides for Hutchinson-Gilford progeria syndrome.
PubMed Identifier: 34075250
author list: Puttaraju M, Jackson M, Klein S, Shilo A, Bennett CF, Gordon L, Rigo F, Misteli T
published in: Nature medicine
information resource reference: Author Correction: Systematic screening identifies therapeutic antisense oligonucleotides for Hutchinson-Gilford progeria syndrome. Nat Med. 2021 Jul; 27(7):1309.
journal title abbreviation: Nat Med
publication date: 2021-07-01T00:00:00
year: 2021
type: Academic Article
type: Article
type: Document
type: Information Resource

Kreienkamp, Raymond
eCommons Login: rak172
first name: Raymond
last name: Kreienkamp
full name: Raymond Kreienkamp, M.D., Ph.D.
has faculty rank: Instructor
Person ID: 199082
person in primary position: Instructor in Pediatrics
type: Agent
type: Person
preferred title: Instructor in Pediatrics

Authorship 1377356
type: Authorship
author rank in publication: 3
linked author: Gordon, Leslie
linked information resource: Base editor treats progeria in mice.

Base editor treats progeria in mice.
PubMed Identifier: 34285403
author list: Koblan LW, Erdos MR, Gordon LB, Collins FS, Brown JD, Liu DR
published in: Nature
information resource reference: Base editor treats progeria in mice. Nature. 2021 Jun 18.
journal title abbreviation: Nature
publication date: 2021-06-18T00:00:00
year: 2021
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1400897
type: Authorship
author rank in publication: 6
linked author: Gordon, Leslie
linked information resource: A novel homozygous synonymous variant further expands the phenotypic spectrum of POLR3A-related pathologies.

A novel homozygous synonymous variant further expands the phenotypic spectrum of POLR3A-related pathologies.
PubMed Identifier: 34611991
author list: Lessel D, Rading K, Campbell SE, Thiele H, Altmüller J, Gordon LB, Kubisch C
published in: American journal of medical genetics. Part A
information resource reference: A novel homozygous synonymous variant further expands the phenotypic spectrum of POLR3A-related pathologies. Am J Med Genet A. 2022 01; 188(1):216-223.
journal title abbreviation: Am J Med Genet A
publication date: 2021-10-05T00:00:00
year: 2021
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 281823
type: Authorship
author rank in publication: 2
linked author: Gordon, Leslie
linked information resource: Hutchinson-Gilford progeria is a skeletal dysplasia.

Authorship 1462964
type: Authorship
author rank in publication: 10
linked author: Gordon, Leslie
linked information resource: Clonal hematopoiesis is not prevalent in Hutchinson-Gilford progeria syndrome.

Clonal hematopoiesis is not prevalent in Hutchinson-Gilford progeria syndrome.
PubMed Identifier: 35752705
author list: Díez-Díez M, Amorós-Pérez M, de la Barrera J, Vázquez E, Quintas A, Pascual-Figal DA, Dopazo A, Sánchez-Cabo F, Kleinman ME, Gordon LB, Fuster V, Andrés V, Fuster JJ
published in: GeroScience
information resource reference: Clonal hematopoiesis is not prevalent in Hutchinson-Gilford progeria syndrome. Geroscience. 2023 04; 45(2):1231-1236.
journal title abbreviation: Geroscience
publication date: 2022-06-25T00:00:00
year: 2022
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1491730
type: Authorship
author rank in publication: 4
linked author: Gordon, Leslie
linked information resource: Sample size determination for the association between longitudinal and time-to-event outcomes using the joint modeling time-dependent slopes parameterization.

Sample size determination for the association between longitudinal and time-to-event outcomes using the joint modeling time-dependent slopes parameterization.
PubMed Identifier: 36305571
author list: LeClair J, Massaro J, Sverdlov O, Gordon L, Tripodis Y
published in: Statistics in medicine
information resource reference: Sample size determination for the association between longitudinal and time-to-event outcomes using the joint modeling time-dependent slopes parameterization. Stat Med. 2022 12 30; 41(30):5810-5829.
journal title abbreviation: Stat Med
publication date: 2022-10-28T00:00:00
year: 2022
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1516644
type: Authorship
author rank in publication: 13
linked author: Gordon, Leslie
linked information resource: Baseline Range of Motion, Strength, Motor Function, and Participation in Youth with Hutchinson-Gilford Progeria Syndrome.

Baseline Range of Motion, Strength, Motor Function, and Participation in Youth with Hutchinson-Gilford Progeria Syndrome.
PubMed Identifier: 36628480
author list: Malloy J, Berry E, Correia A, Fragala-Pinkham M, Coucci S, Riley S, Spratt J, Knight Pfaffinger J, Massaro J, Ehrbar R, D'Agostino R, Gurary EB, Gordon LB, Kleinman ME
published in: Physical & occupational therapy in pediatrics
information resource reference: Baseline Range of Motion, Strength, Motor Function, and Participation in Youth with Hutchinson-Gilford Progeria Syndrome. Phys Occup Ther Pediatr. 2023; 43(4):482-501.
journal title abbreviation: Phys Occup Ther Pediatr
publication date: 2023-01-10T00:00:00
year: 2023
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1531176
type: Authorship
author rank in publication: 10
linked author: Gordon, Leslie
linked information resource: Lonafarnib improves cardiovascular function and survival in a mouse model of Hutchinson-Gilford progeria syndrome.

Authorship 1531042
type: Authorship
author rank in publication: 1
linked author: Gordon, Leslie
linked information resource: Plasma Progerin in Patients With Hutchinson-Gilford Progeria Syndrome: Immunoassay Development and Clinical Evaluation.

Plasma Progerin in Patients With Hutchinson-Gilford Progeria Syndrome: Immunoassay Development and Clinical Evaluation.
PubMed Identifier: 36919608
author list: Gordon LB, Norris W, Hamren S, Goodson R, LeClair J, Massaro J, Lyass A, D'Agostino RB, Tuminelli K, Kieran MW, Kleinman ME
published in: Circulation
information resource reference: Plasma Progerin in Patients With Hutchinson-Gilford Progeria Syndrome: Immunoassay Development and Clinical Evaluation. Circulation. 2023 06 06; 147(23):1734-1744.
journal title abbreviation: Circulation
publication date: 2023-03-15T00:00:00
year: 2023
type: Academic Article
type: Article
type: Document
type: Information Resource

Lonafarnib improves cardiovascular function and survival in a mouse model of Hutchinson-Gilford progeria syndrome.
PubMed Identifier: 36930696
author list: Murtada SI, Mikush N, Wang M, Ren P, Kawamura Y, Ramachandra AB, Li DS, Braddock DT, Tellides G, Gordon LB, Humphrey JD
published in: eLife
information resource reference: Lonafarnib improves cardiovascular function and survival in a mouse model of Hutchinson-Gilford progeria syndrome. Elife. 2023 03 17; 12.
journal title abbreviation: Elife
publication date: 2023-03-17T00:00:00
year: 2023
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 250557
type: Authorship
author rank in publication: 3
linked author: Gordon, Leslie
linked information resource: Aggrecan expression is substantially and abnormally upregulated in Hutchinson-Gilford Progeria Syndrome dermal fibroblasts.

Authorship 1569204
type: Authorship
author rank in publication: 2
linked author: Gordon, Leslie
linked information resource: Progression of Cardiac Abnormalities in Hutchinson-Gilford Progeria Syndrome: A Prospective Longitudinal Study.

Progression of Cardiac Abnormalities in Hutchinson-Gilford Progeria Syndrome: A Prospective Longitudinal Study.
PubMed Identifier: 37276254
author list: Olsen FJ, Gordon LB, Smoot L, Kleinman ME, Gerhard-Herman M, Hegde SM, Mukundan S, Mahoney T, Massaro J, Ha S, Prakash A
published in: Circulation
information resource reference: Progression of Cardiac Abnormalities in Hutchinson-Gilford Progeria Syndrome: A Prospective Longitudinal Study. Circulation. 2023 06 06; 147(23):1782-1784.
journal title abbreviation: Circulation
publication date: 2023-06-05T00:00:00
year: 2023
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1609231
type: Authorship
author rank in publication: 5
linked author: Gordon, Leslie
linked information resource: The farnesyl transferase inhibitor (FTI) lonafarnib improves nuclear morphology in ZMPSTE24-deficient fibroblasts from patients with the progeroid disorder MAD-B.

The farnesyl transferase inhibitor (FTI) lonafarnib improves nuclear morphology in ZMPSTE24-deficient fibroblasts from patients with the progeroid disorder MAD-B.
PubMed Identifier: 38050983
author list: Odinammadu KO, Shilagardi K, Tuminelli K, Judge DP, Gordon LB, Michaelis S
published in: Nucleus (Austin, Tex.)
information resource reference: The farnesyl transferase inhibitor (FTI) lonafarnib improves nuclear morphology in ZMPSTE24-deficient fibroblasts from patients with the progeroid disorder MAD-B. Nucleus. 2023 12; 14(1):2288476.
journal title abbreviation: Nucleus
publication date: 2023-12-05T00:00:00
year: 2023
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 503681
type: Authorship
author rank in publication: 1
linked author: Gordon, Leslie
linked information resource: Growth of P511 mastocytoma cells in BALB/c mouse brain elicits CTL response without tumor elimination: a new tumor model for regional central nervous system immunity.

Authorship 1619823
type: Authorship
author rank in publication: 4
linked author: Gordon, Leslie
linked information resource: Epidemiological characteristics of patients with Hutchinson-Gilford progeria syndrome and progeroid laminopathies in China.

Epidemiological characteristics of patients with Hutchinson-Gilford progeria syndrome and progeroid laminopathies in China.
PubMed Identifier: 38191824
author list: Wang J, Yu Q, Tang X, Gordon LB, Chen J, Jiang B, Huang G, Fu H, Qian J, Liu Z, Mao J
published in: Pediatric research
information resource reference: Epidemiological characteristics of patients with Hutchinson-Gilford progeria syndrome and progeroid laminopathies in China. Pediatr Res. 2024 Apr; 95(5):1356-1362.
journal title abbreviation: Pediatr Res
publication date: 2024-01-08T00:00:00
year: 2024
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1626251
type: Authorship
author rank in publication: 11
linked author: Gordon, Leslie
linked information resource: Abnormal Myocardial Deformation Despite Normal Ejection Fraction in Hutchinson-Gilford Progeria Syndrome.

Abnormal Myocardial Deformation Despite Normal Ejection Fraction in Hutchinson-Gilford Progeria Syndrome.
PubMed Identifier: 38293952
author list: Olsen FJ, Biering-Sørensen T, Lunze F, Hegde SM, Colan SD, Ehrbar R, Massaro J, Ferraro AM, Harrild DM, Kleinman ME, Gordon LB, Prakash A
published in: Journal of the American Heart Association
information resource reference: Abnormal Myocardial Deformation Despite Normal Ejection Fraction in Hutchinson-Gilford Progeria Syndrome. J Am Heart Assoc. 2024 Feb 06; 13(3):e031470.
journal title abbreviation: J Am Heart Assoc
publication date: 2024-01-31T00:00:00
year: 2024
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1647585
type: Authorship
author rank in publication: 1
linked author: Gordon, Leslie
linked information resource: Intervention for critical aortic stenosis in Hutchinson-Gilford progeria syndrome.

Intervention for critical aortic stenosis in Hutchinson-Gilford progeria syndrome.
PubMed Identifier: 38725831
author list: Gordon LB, Basso S, Maestranzi J, Aikawa E, Clift CL, Cammardella AG, Danesi TH, Del Nido PJ, Edelman ER, Hamdy A, Hegde SM, Kleinman ME, Maschietto N, Mehra MR, Mukundan S, Musumeci F, Russo M, Rybicki FJ, Shah PB, Suarez WA, Tuminelli K, Zaleski K, Prakash A, Gerhard-Herman M
published in: Frontiers in cardiovascular medicine
information resource reference: Intervention for critical aortic stenosis in Hutchinson-Gilford progeria syndrome. Front Cardiovasc Med. 2024; 11:1356010.
journal title abbreviation: Front Cardiovasc Med
publication date: 2024-04-25T00:00:00
year: 2024
type: Academic Article
type: Article
type: Document
type: Information Resource

Associate Professor of Medicine
is primary position: true
position in department: Medicine
position in division: Cardiology
sort order: 1
type: Position
HR job title: Associate Professor of Medicine
position in organization: Brigham and Women's Hospital

Associate Professor of Orthopedic Surgery
is primary position: true
position in department: Orthopedic Surgery
position in division: https://connects.catalyst.harvard.edu/Profiles/profile/1229413
sort order: 1
type: Position
HR job title: Associate Professor of Orthopedic Surgery
position in organization: Beth Israel Deaconess Medical Center

Authorship 302620
type: Authorship
author rank in publication: 4
linked author: Gordon, Leslie
linked information resource: Naïve adult stem cells from patients with Hutchinson-Gilford progeria syndrome express low levels of progerin in vivo.

Authorship 657631
type: Authorship
author rank in publication: 1
linked author: Gordon, Leslie
linked information resource: Progeria: translational insights from cell biology.

Authorship 644599
type: Authorship
author rank in publication: 4
linked author: Gordon, Leslie
linked information resource: Craniofacial abnormalities in Hutchinson-Gilford progeria syndrome.

Authorship 665431
type: Authorship
author rank in publication: 2
linked author: Gordon, Leslie
linked information resource: Imaging characteristics of cerebrovascular arteriopathy and stroke in Hutchinson-Gilford progeria syndrome.

Authorship 667939
type: Authorship
author rank in publication: 4
linked author: Gordon, Leslie
linked information resource: Neurologic features of Hutchinson-Gilford progeria syndrome after lonafarnib treatment.

Progeria: translational insights from cell biology.
PubMed Identifier: 23027899
author list: Gordon LB, Cao K, Collins FS
published in: The Journal of cell biology
information resource reference: Progeria: translational insights from cell biology. J Cell Biol. 2012 Oct 01; 199(1):9-13.
journal title abbreviation: J Cell Biol
publication date: 2012-10-01T00:00:00
year: 2012
type: Academic Article
type: Article
type: Document
type: Information Resource

Neurologic features of Hutchinson-Gilford progeria syndrome after lonafarnib treatment.
PubMed Identifier: 23897869
author list: Ullrich NJ, Kieran MW, Miller DT, Gordon LB, Cho YJ, Silvera VM, Giobbie-Hurder A, Neuberg D, Kleinman ME
published in: Neurology
information resource reference: Neurologic features of Hutchinson-Gilford progeria syndrome after lonafarnib treatment. Neurology. 2013 Jul 30; 81(5):427-30.
journal title abbreviation: Neurology
publication date: 2013-06-28T00:00:00
year: 2013
type: Academic Article
type: Article
type: Document
type: Information Resource

Imaging characteristics of cerebrovascular arteriopathy and stroke in Hutchinson-Gilford progeria syndrome.
PubMed Identifier: 23179651
author list: Silvera VM, Gordon LB, Orbach DB, Campbell SE, Machan JT, Ullrich NJ
published in: AJNR. American journal of neuroradiology
information resource reference: Imaging characteristics of cerebrovascular arteriopathy and stroke in Hutchinson-Gilford progeria syndrome. AJNR Am J Neuroradiol. 2013 May; 34(5):1091-7.
journal title abbreviation: AJNR Am J Neuroradiol
publication date: 2012-11-22T00:00:00
year: 2012
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 89747
type: Authorship
author rank in publication: 16
linked author: Gordon, Leslie
linked information resource: Predictors of acquired lipodystrophy in juvenile-onset dermatomyositis and a gradient of severity.

Authorship 567383
type: Authorship
author rank in publication: 1
linked author: Gordon, Leslie
linked information resource: Normal cerebrospinal fluid suppresses the in vitro development of cytotoxic T cells: role of the brain microenvironment in CNS immune regulation.

Authorship 1723399
type: Authorship
author rank in publication: 10
linked author: Gordon, Leslie
linked information resource: Longitudinal Changes in Myocardial Deformation in Hutchinson-Gilford Progeria Syndrome.

Longitudinal Changes in Myocardial Deformation in Hutchinson-Gilford Progeria Syndrome.
PubMed Identifier: 39818925
author list: Olsen FJ, Biering-Sørensen T, Lunze FI, Hegde SM, Ehrbar R, Massaro J, Ferraro AM, Harrild DM, Kleinman ME, Gordon LB, Prakash A
published in: Circulation. Cardiovascular imaging
information resource reference: Longitudinal Changes in Myocardial Deformation in Hutchinson-Gilford Progeria Syndrome. Circ Cardiovasc Imaging. 2025 Feb; 18(2):e017544.
journal title abbreviation: Circ Cardiovasc Imaging
publication date: 2025-01-17T00:00:00
year: 2025
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 327327
type: Authorship
author rank in publication: 5
linked author: Gordon, Leslie
linked information resource: Hutchinson-Gilford progeria syndrome: oral and craniofacial phenotypes.

Authorship 1753911
type: Authorship
author rank in publication: 7
linked author: Gordon, Leslie
linked information resource: Baricitinib and Lonafarnib Synergistically Target Progerin and Inflammation, Improving Lifespan and Health in Progeria Mice.

Baricitinib and Lonafarnib Synergistically Target Progerin and Inflammation, Improving Lifespan and Health in Progeria Mice.
PubMed Identifier: 40429989
author list: Krüger P, Schroll M, Fenzl FQ, Hartinger R, Lederer EM, Görlach A, Gordon LB, Cavalcante P, Iacomino N, Rathkolb B, Pimentel JAA, Östereicher M, Spielmann N, Wolf CM, de Angelis MH, Djabali K
published in: International journal of molecular sciences
information resource reference: Baricitinib and Lonafarnib Synergistically Target Progerin and Inflammation, Improving Lifespan and Health in Progeria Mice. Int J Mol Sci. 2025 May 19; 26(10).
journal title abbreviation: Int J Mol Sci
publication date: 2025-05-19T00:00:00
year: 2025
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 25796
type: Authorship
author rank in publication: 8
linked author: Gordon, Leslie
linked information resource: Defective lamin A-Rb signaling in Hutchinson-Gilford Progeria Syndrome and reversal by farnesyltransferase inhibition.

Authorship 207565
type: Authorship
author rank in publication: 2
linked author: Gordon, Leslie
linked information resource: Phenotype and course of Hutchinson-Gilford progeria syndrome.

Authorship 414580
type: Authorship
author rank in publication: 15
linked author: Gordon, Leslie
linked information resource: Progressive vascular smooth muscle cell defects in a mouse model of Hutchinson-Gilford progeria syndrome.

The Progeria Research Foundation 12th Annual International Scientific Workshop: Coming of Age - Progeria Research Reaching for the Cure
end date: 2026-08-31
principal investigator name: GORDON, LESLIE B
start date: 2025-09-15
type: Grant
sponsor award id: R13AG097030

Principal Investigator
type: Researcher Role
researcher role of: Gordon, Leslie
contributes to: The Progeria Research Foundation 12th Annual International Scientific Workshop: Coming of Age - Progeria Research Reaching for the Cure

Authorship 720534
type: Authorship
author rank in publication: 1
linked author: Gordon, Leslie
linked information resource: Progeria: a paradigm for translational medicine.

Authorship 713432
type: Authorship
author rank in publication: 3
linked author: Gordon, Leslie
linked information resource: Initial cutaneous manifestations of Hutchinson-Gilford progeria syndrome.

Authorship 337815
type: Authorship
author rank in publication: 11
linked author: Gordon, Leslie
linked information resource: Age-dependent loss of MMP-3 in Hutchinson-Gilford progeria syndrome.

Initial cutaneous manifestations of Hutchinson-Gilford progeria syndrome.
PubMed Identifier: 24456199
author list: Rork JF, Huang JT, Gordon LB, Kleinman M, Kieran MW, Liang MG
published in: Pediatric dermatology
information resource reference: Initial cutaneous manifestations of Hutchinson-Gilford progeria syndrome. Pediatr Dermatol. 2014 Mar-Apr; 31(2):196-202.
journal title abbreviation: Pediatr Dermatol
publication date: 2014-01-24T00:00:00
year: 2014
type: Academic Article
type: Article
type: Document
type: Information Resource

Progeria: a paradigm for translational medicine.
PubMed Identifier: 24485450
author list: Gordon LB, Rothman FG, López-Otín C, Misteli T
published in: Cell
information resource reference: Progeria: a paradigm for translational medicine. Cell. 2014 Jan 30; 156(3):400-7.
journal title abbreviation: Cell
publication date: 2014-01-30T00:00:00
year: 2014
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1794216
type: Authorship
author rank in publication: 2
linked author: Gordon, Leslie
linked information resource: Lonafarnib Clinical Trials Demonstrate Uncoupling of the Muscle-Bone Unit in Hutchinson-Gilford Progeria Syndrome.

Authorship 1797637
type: Authorship
author rank in publication: 1
linked author: Gordon, Leslie
linked information resource: Delayed and intermittent CPR for severe accidental hypothermia.

Authorship 1798550
type: Authorship
author rank in publication: 2
linked author: Gordon, Leslie
linked information resource: Accidental hypothermia-an update : The content of this review is endorsed by the International Commission for Mountain Emergency Medicine (ICAR MEDCOM).

Authorship 1806127
type: Authorship
author rank in publication: 11
linked author: Gordon, Leslie
linked information resource: Studies of hypothermic cardiac arrest outcomes without core temperature measurements are deeply flawed.

Authorship 1811648
type: Authorship
author rank in publication: 4
linked author: Gordon, Leslie
linked information resource: Resuscitation of an Unconscious Victim of Accidental Hypothermia in 1805.

Authorship 1831342
type: Authorship
author rank in publication: 9
linked author: Gordon, Leslie
linked information resource: ELSO 2025 Narrative Guideline on the Use of ECMO for Accidental Hypothermia.

Authorship 1841271
type: Authorship
author rank in publication: 7
linked author: Gordon, Leslie
linked information resource: Survival in a Collapsed Stable for 37 Days After Avalanche Burial in 1755.

Authorship 1851160
type: Authorship
author rank in publication: 4
linked author: Gordon, Leslie
linked information resource: About Rewarming Young Children After Drowning-Associated Hypothermia and Out-of-Hospital Cardiac Arrest.

Resuscitation of an Unconscious Victim of Accidental Hypothermia in 1805.
PubMed Identifier: 34620550
author list: Wallner B, Giesbrecht G, Pasquier M, Gordon L, Lechner R, Brugger H, Paal P, Darocha T, Zafren K
published in: Wilderness & environmental medicine
information resource reference: Resuscitation of an Unconscious Victim of Accidental Hypothermia in 1805. Wilderness Environ Med. 2021 Dec; 32(4):548-553.
journal title abbreviation: Wilderness Environ Med
publication date: 2021-10-05T00:00:00
year: 2021
type: Academic Article
type: Article
type: Document
type: Information Resource

Studies of hypothermic cardiac arrest outcomes without core temperature measurements are deeply flawed.
PubMed Identifier: 39304476
author list: Lechner R, Brugger H, Cools E, Darocha T, Paal P, Pasquier M, Strapazzon G, Wallner B, Walpoth B, Zafren K, Gordon L
published in: The American journal of emergency medicine
information resource reference: Studies of hypothermic cardiac arrest outcomes without core temperature measurements are deeply flawed. Am J Emerg Med. 2024 Nov; 85:243-244.
journal title abbreviation: Am J Emerg Med
publication date: 2024-09-12T00:00:00
year: 2024
type: Academic Article
type: Article
type: Document
type: Information Resource

ELSO 2025 Narrative Guideline on the Use of ECMO for Accidental Hypothermia.
PubMed Identifier: 41128452
author list: Cools E, Swol J, Wanscher M, Brugger H, Pasquier M, McIntosh S, Musi M, Oshiro K, Gordon L, Walpoth B, Hoffman JRH, Follis F, Zafren K, Paal P, Giraud R, Podsiadlo P, Martucci G, Darocha T
published in: ASAIO journal (American Society for Artificial Internal Organs : 1992)
information resource reference: ELSO 2025 Narrative Guideline on the Use of ECMO for Accidental Hypothermia. ASAIO J. 2025 Nov 01; 71(11):865-874.
journal title abbreviation: ASAIO J
publication date: 2025-10-22T00:00:00
year: 2025
type: Academic Article
type: Article
type: Document
type: Information Resource

Delayed and intermittent CPR for severe accidental hypothermia.
PubMed Identifier: 25725297
author list: Gordon L, Paal P, Ellerton JA, Brugger H, Peek GJ, Zafren K
published in: Resuscitation
information resource reference: Delayed and intermittent CPR for severe accidental hypothermia. Resuscitation. 2015 May; 90:46-9.
journal title abbreviation: Resuscitation
publication date: 2015-02-25T00:00:00
year: 2015
type: Academic Article
type: Article
type: Document
type: Information Resource

Accidental hypothermia-an update : The content of this review is endorsed by the International Commission for Mountain Emergency Medicine (ICAR MEDCOM).
PubMed Identifier: 27633781
author list: Paal P, Gordon L, Strapazzon G, Brodmann Maeder M, Putzer G, Walpoth B, Wanscher M, Brown D, Holzer M, Broessner G, Brugger H
published in: Scandinavian journal of trauma, resuscitation and emergency medicine
information resource reference: Accidental hypothermia-an update : The content of this review is endorsed by the International Commission for Mountain Emergency Medicine (ICAR MEDCOM). Scand J Trauma Resusc Emerg Med. 2016 Sep 15; 24(1):111.
journal title abbreviation: Scand J Trauma Resusc Emerg Med
publication date: 2016-09-15T00:00:00
year: 2016
type: Academic Article
type: Article
type: Document
type: Information Resource

Survival in a Collapsed Stable for 37 Days After Avalanche Burial in 1755.
PubMed Identifier: 36526516
author list: Lechner R, Brugger H, Paal P, Hüfner K, Agazzi G, Butler F, Gordon L, Darocha T, Zafren K
published in: Wilderness & environmental medicine
information resource reference: Survival in a Collapsed Stable for 37 Days After Avalanche Burial in 1755. Wilderness Environ Med. 2023 03; 34(1):113-119.
journal title abbreviation: Wilderness Environ Med
publication date: 2022-12-14T00:00:00
year: 2022
type: Academic Article
type: Article
type: Document
type: Information Resource

About Rewarming Young Children After Drowning-Associated Hypothermia and Out-of-Hospital Cardiac Arrest.
PubMed Identifier: 38451805
author list: Cools E, Brugger H, Darocha T, Gordon L, Pasquier M, Walpoth B, Zafren K, Peek G, Paal P
published in: Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies
information resource reference: About Rewarming Young Children After Drowning-Associated Hypothermia and Out-of-Hospital Cardiac Arrest. Pediatr Crit Care Med. 2024 Mar 01; 25(3):e171-e172.
journal title abbreviation: Pediatr Crit Care Med
publication date: 2024-03-01T00:00:00
year: 2024
type: Academic Article
type: Article
type: Document
type: Information Resource

Lonafarnib Clinical Trials Demonstrate Uncoupling of the Muscle-Bone Unit in Hutchinson-Gilford Progeria Syndrome.
PubMed Identifier: 41342417
author list: Kreienkamp RJ, Gordon LB, Ehrbar R, Pendleton A, Schiferl DJ, Lyass A, Kleinman ME, Snyder BD, Gordon CM
published in: Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research
information resource reference: Lonafarnib Clinical Trials Demonstrate Uncoupling of the Muscle-Bone Unit in Hutchinson-Gilford Progeria Syndrome. J Bone Miner Res. 2025 Dec 04.
journal title abbreviation: J Bone Miner Res
publication date: 2025-12-04T00:00:00
year: 2025
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 739458
type: Authorship
author rank in publication: 1
linked author: Gordon, Leslie
linked information resource: Impact of farnesylation inhibitors on survival in Hutchinson-Gilford progeria syndrome.

Impact of farnesylation inhibitors on survival in Hutchinson-Gilford progeria syndrome.
PubMed Identifier: 24795390
author list: Gordon LB, Massaro J, D'Agostino RB, Campbell SE, Brazier J, Brown WT, Kleinman ME, Kieran MW
published in: Circulation
information resource reference: Impact of farnesylation inhibitors on survival in Hutchinson-Gilford progeria syndrome. Circulation. 2014 Jul 01; 130(1):27-34.
journal title abbreviation: Circulation
publication date: 2014-05-02T00:00:00
year: 2014
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 268897
type: Authorship
author rank in publication: 6
linked author: Gordon, Leslie
linked information resource: Accumulation of mutant lamin A causes progressive changes in nuclear architecture in Hutchinson-Gilford progeria syndrome.

Assistant Professor of Anaesthesia
is primary position: true
position in department: Anaesthesia
position in division: https://connects.catalyst.harvard.edu/Profiles/profile/1229413
sort order: 1
type: Position
HR job title: Assistant Professor of Anaesthesia
position in organization: Boston Children's Hospital

Instructor in Pediatrics
is primary position: true
position in department: Pediatrics
position in division: Endocrinology
sort order: 1
type: Position
HR job title: Instructor in Pediatrics
position in organization: Boston Children's Hospital

Professor of Neurology
is primary position: true
position in department: Neurology
position in division: https://connects.catalyst.harvard.edu/Profiles/profile/1229413
sort order: 1
type: Position
HR job title: Professor of Neurology
position in organization: Boston Children's Hospital

Julia Dyckman Andrus Professor of Surgery
is primary position: true
position in department: Surgery
position in division: https://connects.catalyst.harvard.edu/Profiles/profile/1229413
sort order: 1
type: Position
HR job title: Julia Dyckman Andrus Professor of Surgery
position in organization: Boston Children's Hospital

Instructor in Anaesthesia
is primary position: true
position in department: Anaesthesia
position in division: https://connects.catalyst.harvard.edu/Profiles/profile/1229413
sort order: 1
type: Position
HR job title: Instructor in Anaesthesia
position in organization: Boston Children's Hospital

Instructor in Anaesthesia
is primary position: true
position in department: Anaesthesia
position in division: https://connects.catalyst.harvard.edu/Profiles/profile/1229413
sort order: 1
type: Position
HR job title: Instructor in Anaesthesia
position in organization: Boston Children's Hospital

Assistant Professor of Anaesthesia
is primary position: true
position in department: Anaesthesia
position in division: https://connects.catalyst.harvard.edu/Profiles/profile/1229413
sort order: 1
type: Position
HR job title: Assistant Professor of Anaesthesia
position in organization: Boston Children's Hospital

Associate Professor of Pediatrics
is primary position: true
position in department: Pediatrics
position in division: Cardiology
sort order: 1
type: Position
HR job title: Associate Professor of Pediatrics
position in organization: Boston Children's Hospital

Research Associate in Anaesthesia
is primary position: true
position in department: Anaesthesia
position in division: https://connects.catalyst.harvard.edu/Profiles/profile/1229413
sort order: 1
type: Position
HR job title: Research Associate in Anaesthesia
position in organization: Boston Children's Hospital

Associate Professor of Anaesthesia
is primary position: true
position in department: Anaesthesia
position in division: https://connects.catalyst.harvard.edu/Profiles/profile/1229413
sort order: 1
type: Position
HR job title: Associate Professor of Anaesthesia
position in organization: Boston Children's Hospital

Associate Professor of Anaesthesia (Pediatrics)
is primary position: true
position in department: Anaesthesia
position in division: https://connects.catalyst.harvard.edu/Profiles/profile/1229413
sort order: 1
type: Position
HR job title: Associate Professor of Anaesthesia (Pediatrics)
position in organization: Boston Children's Hospital

Authorship 37333
type: Authorship
author rank in publication: 3
linked author: Gordon, Leslie
linked information resource: Recurrent de novo point mutations in lamin A cause Hutchinson-Gilford progeria syndrome.

Authorship 42536
type: Authorship
author rank in publication: 2
linked author: Gordon, Leslie
linked information resource: A prospective study of radiographic manifestations in Hutchinson-Gilford progeria syndrome.

Authorship 218938
type: Authorship
author rank in publication: 1
linked author: Gordon, Leslie
linked information resource: Disease progression in Hutchinson-Gilford progeria syndrome: impact on growth and development.

Authorship 290854
type: Authorship
author rank in publication: 18
linked author: Gordon, Leslie
linked information resource: Cardiovascular pathology in Hutchinson-Gilford progeria: correlation with the vascular pathology of aging.

Authorship 63255
type: Authorship
author rank in publication: 10
linked author: Gordon, Leslie
linked information resource: Mechanisms of premature vascular aging in children with Hutchinson-Gilford progeria syndrome.

Authorship 49283
type: Authorship
author rank in publication: 1
linked author: Gordon, Leslie
linked information resource: Highlights of the 2007 Progeria Research Foundation scientific workshop: progress in translational science.

Authorship 803414
type: Authorship
author rank in publication: 3
linked author: Gordon, Leslie
linked information resource: Atherosclerosis in ancient humans, accelerated aging syndromes and normal aging: is lamin a protein a common link?

Authorship 807337
type: Authorship
author rank in publication: 3
linked author: Gordon, Leslie
linked information resource: Sulforaphane enhances progerin clearance in Hutchinson-Gilford progeria fibroblasts.

Atherosclerosis in ancient humans, accelerated aging syndromes and normal aging: is lamin a protein a common link?
PubMed Identifier: 25667091
author list: Miyamoto MI, Djabali K, Gordon LB
published in: Global heart
information resource reference: Atherosclerosis in ancient humans, accelerated aging syndromes and normal aging: is lamin a protein a common link? Glob Heart. 2014 Jun; 9(2):211-8.
journal title abbreviation: Glob Heart
publication date: 2014-06-01T00:00:00
year: 2014
type: Academic Article
type: Article
type: Document
type: Information Resource

Sulforaphane enhances progerin clearance in Hutchinson-Gilford progeria fibroblasts.
PubMed Identifier: 25510262
author list: Gabriel D, Roedl D, Gordon LB, Djabali K
published in: Aging cell
information resource reference: Sulforaphane enhances progerin clearance in Hutchinson-Gilford progeria fibroblasts. Aging Cell. 2015 Feb; 14(1):78-91.
journal title abbreviation: Aging Cell
publication date: 2014-12-16T00:00:00
year: 2014
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 277974
type: Authorship
author rank in publication: 1
linked author: Gordon, Leslie
linked information resource: Reduced adiponectin and HDL cholesterol without elevated C-reactive protein: clues to the biology of premature atherosclerosis in Hutchinson-Gilford Progeria Syndrome.

Authorship 849315
type: Authorship
author rank in publication: 2
linked author: Gordon, Leslie
linked information resource: Hutchinson-Gilford progeria syndrome.

Hutchinson-Gilford progeria syndrome.
PubMed Identifier: 26564085
author list: Ullrich NJ, Gordon LB
published in: Handbook of clinical neurology
information resource reference: Hutchinson-Gilford progeria syndrome. Handb Clin Neurol. 2015; 132:249-64.
journal title abbreviation: Handb Clin Neurol
publication date: 2015-01-01T00:00:00
year: 2015
type: Academic Article
type: Article
type: Document
type: Information Resource

Assistant Professor
sort order: 2
type: Faculty Rank

Associate Professor
sort order: 1
type: Faculty Rank

Full Professor
sort order: 0
type: Faculty Rank

Instructor
sort order: 4
type: Faculty Rank

Other Faculty
sort order: 5
type: Faculty Rank

Authorship 892061
type: Authorship
author rank in publication: 1
linked author: Gordon, Leslie
linked information resource: Clinical Trial of the Protein Farnesylation Inhibitors Lonafarnib, Pravastatin, and Zoledronic Acid in Children With Hutchinson-Gilford Progeria Syndrome.

Authorship 890739
type: Authorship
author rank in publication: 1
linked author: Gordon, Leslie
linked information resource: The decision-making process and criteria in selecting candidate drugs for progeria clinical trials.

Clinical Trial of the Protein Farnesylation Inhibitors Lonafarnib, Pravastatin, and Zoledronic Acid in Children With Hutchinson-Gilford Progeria Syndrome.
PubMed Identifier: 27400896
author list: Gordon LB, Kleinman ME, Massaro J, D'Agostino RB, Shappell H, Gerhard-Herman M, Smoot LB, Gordon CM, Cleveland RH, Nazarian A, Snyder BD, Ullrich NJ, Silvera VM, Liang MG, Quinn N, Miller DT, Huh SY, Dowton AA, Littlefield K, Greer MM, Kieran MW
published in: Circulation
information resource reference: Clinical Trial of the Protein Farnesylation Inhibitors Lonafarnib, Pravastatin, and Zoledronic Acid in Children With Hutchinson-Gilford Progeria Syndrome. Circulation. 2016 Jul 12; 134(2):114-25.
journal title abbreviation: Circulation
publication date: 2016-07-12T00:00:00
year: 2016
type: Academic Article
type: Article
type: Document
type: Information Resource

The decision-making process and criteria in selecting candidate drugs for progeria clinical trials.
PubMed Identifier: 27234439
author list: Gordon LB, Kieran MW, Kleinman ME, Misteli T
published in: EMBO molecular medicine
information resource reference: The decision-making process and criteria in selecting candidate drugs for progeria clinical trials. EMBO Mol Med. 2016 07; 8(7):685-7.
journal title abbreviation: EMBO Mol Med
publication date: 2016-07-01T00:00:00
year: 2016
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 495974
type: Authorship
author rank in publication: 7
linked author: Gordon, Leslie
linked information resource: Inhibiting farnesylation of progerin prevents the characteristic nuclear blebbing of Hutchinson-Gilford progeria syndrome.

PRF 10th Anniversary Workshop on Progeria - "From Bench to Bedside in a Decade"
end date: 2011-03-31
principal investigator name: GORDON, LESLIE B
start date: 2010-04-01
type: Grant
sponsor award id: R13HL103229

The 2007 Progeria Research Foundation Workshop on Hutchinson Gilford Progeria
end date: 2008-08-31
principal investigator name: GORDON, LESLIE B
start date: 2007-09-21
type: Grant
sponsor award id: R13HL091695

Creating a Medical and Research Database for HGPS
end date: 2006-02-28
principal investigator name: GORDON, LESLIE B
start date: 2003-06-01
type: Grant
sponsor award id: R21AG021902

The Progeria Research Foundation International Progeria Workshop
end date: 2007-01-31
principal investigator name: GORDON, LESLIE B
start date: 2006-02-01
type: Grant
sponsor award id: R13HL085078

The Progeria Research Foundation 8th International Scientific Workshop Across the Table, Around the Globe
end date: 2017-04-30
principal investigator name: GORDON, LESLIE B
start date: 2016-05-01
type: Grant
sponsor award id: R13AG054149

PRF 11th Anniversary Workshop on Progeria - Hand in Hand: Basic and Clinica
end date: 2014-03-31
principal investigator name: GORDON, LESLIE B
start date: 2013-04-01
type: Grant
sponsor award id: R13AG046918

Principal Investigator
type: Researcher Role
researcher role of: Gordon, Leslie
contributes to: Creating a Medical and Research Database for HGPS

Principal Investigator
type: Researcher Role
researcher role of: Gordon, Leslie
contributes to: The Progeria Research Foundation International Progeria Workshop

Principal Investigator
type: Researcher Role
researcher role of: Gordon, Leslie
contributes to: The Progeria Research Foundation 8th International Scientific Workshop Across the Table, Around the Globe

Principal Investigator
type: Researcher Role
researcher role of: Gordon, Leslie
contributes to: PRF 11th Anniversary Workshop on Progeria - Hand in Hand: Basic and Clinica

Principal Investigator
type: Researcher Role
researcher role of: Gordon, Leslie
contributes to: The 2007 Progeria Research Foundation Workshop on Hutchinson Gilford Progeria

Principal Investigator
type: Researcher Role
researcher role of: Gordon, Leslie
contributes to: PRF 10th Anniversary Workshop on Progeria - "From Bench to Bedside in a Decade"

Authorship 541416
type: Authorship
author rank in publication: 1
linked author: Gordon, Leslie
linked information resource: Hyaluronan is not elevated in urine or serum in Hutchinson-Gilford Progeria Syndrome.

Authorship 934039
type: Authorship
author rank in publication: 15
linked author: Gordon, Leslie
linked information resource: Cardiac electrical defects in progeroid mice and Hutchinson-Gilford progeria syndrome patients with nuclear lamina alterations.

Cardiac electrical defects in progeroid mice and Hutchinson-Gilford progeria syndrome patients with nuclear lamina alterations.
PubMed Identifier: 27799555
author list: Rivera-Torres J, Calvo CJ, Llach A, Guzmán-Martínez G, Caballero R, González-Gómez C, Jiménez-Borreguero LJ, Guadix JA, Osorio FG, López-Otín C, Herraiz-Martínez A, Cabello N, Vallmitjana A, Benítez R, Gordon LB, Jalife J, Pérez-Pomares JM, Tamargo J, Delpón E, Hove-Madsen L, Filgueiras-Rama D, Andrés V
published in: Proceedings of the National Academy of Sciences of the United States of America
information resource reference: Cardiac electrical defects in progeroid mice and Hutchinson-Gilford progeria syndrome patients with nuclear lamina alterations. Proc Natl Acad Sci U S A. 2016 11 15; 113(46):E7250-E7259.
journal title abbreviation: Proc Natl Acad Sci U S A
publication date: 2016-10-31T00:00:00
year: 2016
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 200179
type: Authorship
author rank in publication: 2
linked author: Gordon, Leslie
linked information resource: New approaches to progeria.

Authorship 300664
type: Authorship
author rank in publication: 1
linked author: Gordon, Leslie
linked information resource: Clinical trial of a farnesyltransferase inhibitor in children with Hutchinson-Gilford progeria syndrome.

Authorship 947060
type: Authorship
author rank in publication: 2
linked author: Gordon, Leslie
linked information resource: Temsirolimus Partially Rescues the Hutchinson-Gilford Progeria Cellular Phenotype.

Temsirolimus Partially Rescues the Hutchinson-Gilford Progeria Cellular Phenotype.
PubMed Identifier: 28033363
author list: Gabriel D, Gordon LB, Djabali K
published in: PloS one
information resource reference: Temsirolimus Partially Rescues the Hutchinson-Gilford Progeria Cellular Phenotype. PLoS One. 2016; 11(12):e0168988.
journal title abbreviation: PLoS One
publication date: 2016-12-29T00:00:00
year: 2016
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 966195
type: Authorship
author rank in publication: 11
linked author: Gordon, Leslie
linked information resource: A novel somatic mutation achieves partial rescue in a child with Hutchinson-Gilford progeria syndrome.

A novel somatic mutation achieves partial rescue in a child with Hutchinson-Gilford progeria syndrome.
PubMed Identifier: 27920058
author list: Bar DZ, Arlt MF, Brazier JF, Norris WE, Campbell SE, Chines P, Larrieu D, Jackson SP, Collins FS, Glover TW, Gordon LB
published in: Journal of medical genetics
information resource reference: A novel somatic mutation achieves partial rescue in a child with Hutchinson-Gilford progeria syndrome. J Med Genet. 2017 03; 54(3):212-216.
journal title abbreviation: J Med Genet
publication date: 2016-12-05T00:00:00
year: 2016
type: Academic Article
type: Article
type: Document
type: Information Resource

New approaches to progeria.
PubMed Identifier: 17908771
author list: Kieran MW, Gordon L, Kleinman M
published in: Pediatrics
information resource reference: New approaches to progeria. Pediatrics. 2007 Oct; 120(4):834-41.
journal title abbreviation: Pediatrics
publication date: 2007-10-01T00:00:00
year: 2007
type: Academic Article
type: Article
type: Document
type: Information Resource

Growth of P511 mastocytoma cells in BALB/c mouse brain elicits CTL response without tumor elimination: a new tumor model for regional central nervous system immunity.
PubMed Identifier: 9278331
author list: Gordon LB, Nolan SC, Cserr HF, Knopf PM, Harling-Berg CJ
published in: Journal of immunology (Baltimore, Md. : 1950)
information resource reference: Growth of P511 mastocytoma cells in BALB/c mouse brain elicits CTL response without tumor elimination: a new tumor model for regional central nervous system immunity. J Immunol. 1997 Sep 01; 159(5):2399-408.
journal title abbreviation: J Immunol
publication date: 1997-09-01T00:00:00
year: 1997
type: Academic Article
type: Article
type: Document
type: Information Resource

Normal cerebrospinal fluid suppresses the in vitro development of cytotoxic T cells: role of the brain microenvironment in CNS immune regulation.
PubMed Identifier: 9688327
author list: Gordon LB, Nolan SC, Ksander BR, Knopf PM, Harling-Berg CJ
published in: Journal of neuroimmunology
information resource reference: Normal cerebrospinal fluid suppresses the in vitro development of cytotoxic T cells: role of the brain microenvironment in CNS immune regulation. J Neuroimmunol. 1998 Aug 01; 88(1-2):77-84.
journal title abbreviation: J Neuroimmunol
publication date: 1998-08-01T00:00:00
year: 1998
type: Academic Article
type: Article
type: Document
type: Information Resource

Progressive vascular smooth muscle cell defects in a mouse model of Hutchinson-Gilford progeria syndrome.
PubMed Identifier: 16492728
author list: Varga R, Eriksson M, Erdos MR, Olive M, Harten I, Kolodgie F, Capell BC, Cheng J, Faddah D, Perkins S, Avallone H, San H, Qu X, Ganesh S, Gordon LB, Virmani R, Wight TN, Nabel EG, Collins FS
published in: Proceedings of the National Academy of Sciences of the United States of America
information resource reference: Progressive vascular smooth muscle cell defects in a mouse model of Hutchinson-Gilford progeria syndrome. Proc Natl Acad Sci U S A. 2006 Feb 28; 103(9):3250-5.
journal title abbreviation: Proc Natl Acad Sci U S A
publication date: 2006-02-21T00:00:00
year: 2006
type: Academic Article
type: Article
type: Document
type: Information Resource

Cardiovascular pathology in Hutchinson-Gilford progeria: correlation with the vascular pathology of aging.
PubMed Identifier: 20798379
author list: Olive M, Harten I, Mitchell R, Beers JK, Djabali K, Cao K, Erdos MR, Blair C, Funke B, Smoot L, Gerhard-Herman M, Machan JT, Kutys R, Virmani R, Collins FS, Wight TN, Nabel EG, Gordon LB
published in: Arteriosclerosis, thrombosis, and vascular biology
information resource reference: Cardiovascular pathology in Hutchinson-Gilford progeria: correlation with the vascular pathology of aging. Arterioscler Thromb Vasc Biol. 2010 Nov; 30(11):2301-9.
journal title abbreviation: Arterioscler Thromb Vasc Biol
publication date: 2010-08-26T00:00:00
year: 2010
type: Academic Article
type: Article
type: Document
type: Information Resource

Inhibiting farnesylation of progerin prevents the characteristic nuclear blebbing of Hutchinson-Gilford progeria syndrome.
PubMed Identifier: 16129833
author list: Capell BC, Erdos MR, Madigan JP, Fiordalisi JJ, Varga R, Conneely KN, Gordon LB, Der CJ, Cox AD, Collins FS
published in: Proceedings of the National Academy of Sciences of the United States of America
information resource reference: Inhibiting farnesylation of progerin prevents the characteristic nuclear blebbing of Hutchinson-Gilford progeria syndrome. Proc Natl Acad Sci U S A. 2005 Sep 06; 102(36):12879-84.
journal title abbreviation: Proc Natl Acad Sci U S A
publication date: 2005-08-29T00:00:00
year: 2005
type: Academic Article
type: Article
type: Document
type: Information Resource

Aggrecan expression is substantially and abnormally upregulated in Hutchinson-Gilford Progeria Syndrome dermal fibroblasts.
PubMed Identifier: 16650460
author list: Lemire JM, Patis C, Gordon LB, Sandy JD, Toole BP, Weiss AS
published in: Mechanisms of ageing and development
information resource reference: Aggrecan expression is substantially and abnormally upregulated in Hutchinson-Gilford Progeria Syndrome dermal fibroblasts. Mech Ageing Dev. 2006 Aug; 127(8):660-9.
journal title abbreviation: Mech Ageing Dev
publication date: 2006-05-02T00:00:00
year: 2006
type: Academic Article
type: Article
type: Document
type: Information Resource

The mutant form of lamin A that causes Hutchinson-Gilford progeria is a biomarker of cellular aging in human skin.
PubMed Identifier: 18060063
author list: McClintock D, Ratner D, Lokuge M, Owens DM, Gordon LB, Collins FS, Djabali K
published in: PloS one
information resource reference: The mutant form of lamin A that causes Hutchinson-Gilford progeria is a biomarker of cellular aging in human skin. PLoS One. 2007 Dec 05; 2(12):e1269.
journal title abbreviation: PLoS One
publication date: 2007-12-05T00:00:00
year: 2007
type: Academic Article
type: Article
type: Document
type: Information Resource

Reduced adiponectin and HDL cholesterol without elevated C-reactive protein: clues to the biology of premature atherosclerosis in Hutchinson-Gilford Progeria Syndrome.
PubMed Identifier: 15756215
author list: Gordon LB, Harten IA, Patti ME, Lichtenstein AH
published in: The Journal of pediatrics
information resource reference: Reduced adiponectin and HDL cholesterol without elevated C-reactive protein: clues to the biology of premature atherosclerosis in Hutchinson-Gilford Progeria Syndrome. J Pediatr. 2005 Mar; 146(3):336-41.
journal title abbreviation: J Pediatr
publication date: 2005-03-01T00:00:00
year: 2005
type: Academic Article
type: Article
type: Document
type: Information Resource

Clinical trial of a farnesyltransferase inhibitor in children with Hutchinson-Gilford progeria syndrome.
PubMed Identifier: 23012407
author list: Gordon LB, Kleinman ME, Miller DT, Neuberg DS, Giobbie-Hurder A, Gerhard-Herman M, Smoot LB, Gordon CM, Cleveland R, Snyder BD, Fligor B, Bishop WR, Statkevich P, Regen A, Sonis A, Riley S, Ploski C, Correia A, Quinn N, Ullrich NJ, Nazarian A, Liang MG, Huh SY, Schwartzman A, Kieran MW
published in: Proceedings of the National Academy of Sciences of the United States of America
information resource reference: Clinical trial of a farnesyltransferase inhibitor in children with Hutchinson-Gilford progeria syndrome. Proc Natl Acad Sci U S A. 2012 Oct 09; 109(41):16666-71.
journal title abbreviation: Proc Natl Acad Sci U S A
publication date: 2012-09-24T00:00:00
year: 2012
type: Academic Article
type: Article
type: Document
type: Information Resource

Disease progression in Hutchinson-Gilford progeria syndrome: impact on growth and development.
PubMed Identifier: 17908770
author list: Gordon LB, McCarten KM, Giobbie-Hurder A, Machan JT, Campbell SE, Berns SD, Kieran MW
published in: Pediatrics
information resource reference: Disease progression in Hutchinson-Gilford progeria syndrome: impact on growth and development. Pediatrics. 2007 Oct; 120(4):824-33.
journal title abbreviation: Pediatrics
publication date: 2007-10-01T00:00:00
year: 2007
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1008402
type: Authorship
author rank in publication: 4
linked author: Gordon, Leslie
linked information resource: Ophthalmologic Features of Progeria.

Ophthalmologic Features of Progeria.
PubMed Identifier: 28756152
author list: Mantagos IS, Kleinman ME, Kieran MW, Gordon LB
published in: American journal of ophthalmology
information resource reference: Ophthalmologic Features of Progeria. Am J Ophthalmol. 2017 Oct; 182:126-132.
journal title abbreviation: Am J Ophthalmol
publication date: 2017-07-27T00:00:00
year: 2017
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1017950
type: Authorship
author rank in publication: 3
linked author: Gordon, Leslie
linked information resource: Intermittent treatment with farnesyltransferase inhibitor and sulforaphane improves cellular homeostasis in Hutchinson-Gilford progeria fibroblasts.

Intermittent treatment with farnesyltransferase inhibitor and sulforaphane improves cellular homeostasis in Hutchinson-Gilford progeria fibroblasts.
PubMed Identifier: 29029393
author list: Gabriel D, Shafry DD, Gordon LB, Djabali K
published in: Oncotarget
information resource reference: Intermittent treatment with farnesyltransferase inhibitor and sulforaphane improves cellular homeostasis in Hutchinson-Gilford progeria fibroblasts. Oncotarget. 2017 Sep 12; 8(39):64809-64826.
journal title abbreviation: Oncotarget
publication date: 2017-07-18T00:00:00
year: 2017
type: Academic Article
type: Article
type: Document
type: Information Resource

Accumulation of mutant lamin A causes progressive changes in nuclear architecture in Hutchinson-Gilford progeria syndrome.
PubMed Identifier: 15184648
author list: Goldman RD, Shumaker DK, Erdos MR, Eriksson M, Goldman AE, Gordon LB, Gruenbaum Y, Khuon S, Mendez M, Varga R, Collins FS
published in: Proceedings of the National Academy of Sciences of the United States of America
information resource reference: Accumulation of mutant lamin A causes progressive changes in nuclear architecture in Hutchinson-Gilford progeria syndrome. Proc Natl Acad Sci U S A. 2004 Jun 15; 101(24):8963-8.
journal title abbreviation: Proc Natl Acad Sci U S A
publication date: 2004-06-07T00:00:00
year: 2004
type: Academic Article
type: Article
type: Document
type: Information Resource

300 Longwood Ave
type: Address
address line 1: Childrens Hospital
address line 2: Anesthesia, Pavilion 3
address line 3: 300 Longwood Ave
city: Boston
postal code: 02115
state or province: MA

Authorship 1034873
type: Authorship
author rank in publication: 3
linked author: Gordon, Leslie
linked information resource: Pubertal Progression in Female Adolescents with Progeria.

Pubertal Progression in Female Adolescents with Progeria.
PubMed Identifier: 29258958
author list: Greer MM, Kleinman ME, Gordon LB, Massaro J, D'Agostino RB, Baltrusaitis K, Kieran MW, Gordon CM
published in: Journal of pediatric and adolescent gynecology
information resource reference: Pubertal Progression in Female Adolescents with Progeria. J Pediatr Adolesc Gynecol. 2018 Jun; 31(3):238-241.
journal title abbreviation: J Pediatr Adolesc Gynecol
publication date: 2017-12-16T00:00:00
year: 2017
type: Academic Article
type: Article
type: Document
type: Information Resource

Hutchinson-Gilford progeria is a skeletal dysplasia.
PubMed Identifier: 21445982
author list: Gordon CM, Gordon LB, Snyder BD, Nazarian A, Quinn N, Huh S, Giobbie-Hurder A, Neuberg D, Cleveland R, Kleinman M, Miller DT, Kieran MW
published in: Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research
information resource reference: Hutchinson-Gilford progeria is a skeletal dysplasia. J Bone Miner Res. 2011 Jul; 26(7):1670-9.
journal title abbreviation: J Bone Miner Res
publication date: 2011-07-01T00:00:00
year: 2011
type: Academic Article
type: Article
type: Document
type: Information Resource

Hutchinson-Gilford progeria syndrome: oral and craniofacial phenotypes.
PubMed Identifier: 19236595
author list: Domingo DL, Trujillo MI, Council SE, Merideth MA, Gordon LB, Wu T, Introne WJ, Gahl WA, Hart TC
published in: Oral diseases
information resource reference: Hutchinson-Gilford progeria syndrome: oral and craniofacial phenotypes. Oral Dis. 2009 Apr; 15(3):187-95.
journal title abbreviation: Oral Dis
publication date: 2009-02-19T00:00:00
year: 2009
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1039059
type: Authorship
author rank in publication: 1
linked author: Gordon, Leslie
linked information resource: Survey of plasma proteins in children with progeria pre-therapy and on-therapy with lonafarnib.

Survey of plasma proteins in children with progeria pre-therapy and on-therapy with lonafarnib.
PubMed Identifier: 29342131
author list: Gordon LB, Campbell SE, Massaro JM, D'Agostino RB, Kleinman ME, Kieran MW, Moses MA
published in: Pediatric research
information resource reference: Survey of plasma proteins in children with progeria pre-therapy and on-therapy with lonafarnib. Pediatr Res. 2018 05; 83(5):982-992.
journal title abbreviation: Pediatr Res
publication date: 2018-02-28T00:00:00
year: 2018
type: Academic Article
type: Article
type: Document
type: Information Resource

Predictors of acquired lipodystrophy in juvenile-onset dermatomyositis and a gradient of severity.
PubMed Identifier: 18344805
author list: Bingham A, Mamyrova G, Rother KI, Oral E, Cochran E, Premkumar A, Kleiner D, James-Newton L, Targoff IN, Pandey JP, Carrick DM, Sebring N, O'Hanlon TP, Ruiz-Hidalgo M, Turner M, Gordon LB, Laborda J, Bauer SR, Blackshear PJ, Imundo L, Miller FW, Rider LG
published in: Medicine
information resource reference: Predictors of acquired lipodystrophy in juvenile-onset dermatomyositis and a gradient of severity. Medicine (Baltimore). 2008 Mar; 87(2):70-86.
journal title abbreviation: Medicine (Baltimore)
publication date: 2008-03-01T00:00:00
year: 2008
type: Academic Article
type: Article
type: Document
type: Information Resource

Cardiac Abnormalities in Patients With Hutchinson-Gilford Progeria Syndrome.
PubMed Identifier: 29466530
author list: Prakash A, Gordon LB, Kleinman ME, Gurary EB, Massaro J, D'Agostino R, Kieran MW, Gerhard-Herman M, Smoot L
published in: JAMA cardiology
information resource reference: Cardiac Abnormalities in Patients With Hutchinson-Gilford Progeria Syndrome. JAMA Cardiol. 2018 04 01; 3(4):326-334.
journal title abbreviation: JAMA Cardiol
publication date: 2018-04-01T00:00:00
year: 2018
type: Academic Article
type: Article
type: Document
type: Information Resource

Ovalbumin is more immunogenic when introduced into brain or cerebrospinal fluid than into extracerebral sites.
PubMed Identifier: 1517399
author list: Gordon LB, Knopf PM, Cserr HF
published in: Journal of neuroimmunology
information resource reference: Ovalbumin is more immunogenic when introduced into brain or cerebrospinal fluid than into extracerebral sites. J Neuroimmunol. 1992 Sep; 40(1):81-7.
journal title abbreviation: J Neuroimmunol
publication date: 1992-09-01T00:00:00
year: 1992
type: Academic Article
type: Article
type: Document
type: Information Resource