Shivdasani, Ramesh
eCommons Login: RAS3
first name: Ramesh
last name: Shivdasani
coauthor of: Bhattacharya, Swarnabh
coauthor of: Singh, Pratik
coauthor of: Orkin, Stuart
coauthor of: Singh, Harshabad
coauthor of: Italiano, Joseph
full name: Ramesh Shivdasani, M.D.,Ph.D.
has faculty rank: Full Professor
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Person ID: 59369
person in primary position: Professor of Medicine
physical neighbor: Ivanov, Pavel
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similar to: Orkin, Stuart
similar to: Perrimon, Norbert
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similar to: Daley, George
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selected publications: Authorship 1793787
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Authorship 1049236
type: Authorship
author rank in publication: 12
linked author: Shivdasani, Ramesh
linked information resource: RORa-expressing T regulatory cells restrain allergic skin inflammation.

p45(NFE2) is a negative regulator of erythroid proliferation which contributes to the progression of Friend virus-induced erythroleukemias.
PubMed Identifier: 11113182
author list: Li YJ, Higgins RR, Pak BJ, Shivdasani RA, Ney PA, Archer M, Ben-David Y
published in: Molecular and cellular biology
information resource reference: p45(NFE2) is a negative regulator of erythroid proliferation which contributes to the progression of Friend virus-induced erythroleukemias. Mol Cell Biol. 2001 Jan; 21(1):73-80.
journal title abbreviation: Mol Cell Biol
publication date: 2001-01-01T00:00:00
year: 2001
type: Academic Article
type: Article
type: Document
type: Information Resource

An animal model for myelofibrosis.
PubMed Identifier: 12149182
author list: Shivdasani R
published in: Blood
information resource reference: An animal model for myelofibrosis. Blood. 2002 Aug 15; 100(4):1109.
journal title abbreviation: Blood
publication date: 2002-08-15T00:00:00
year: 2002
type: Academic Article
type: Article
type: Document
type: Information Resource

Lonely in Paris: when one gene copy isn't enough.
PubMed Identifier: 15232606
author list: Shivdasani RA
published in: The Journal of clinical investigation
information resource reference: Lonely in Paris: when one gene copy isn't enough. J Clin Invest. 2004 Jul; 114(1):17-9.
journal title abbreviation: J Clin Invest
publication date: 2004-07-01T00:00:00
year: 2004
type: Academic Article
type: Article
type: Document
type: Information Resource

The stomach mesenchymal transcription factor Barx1 specifies gastric epithelial identity through inhibition of transient Wnt signaling.
PubMed Identifier: 15809042
author list: Kim BM, Buchner G, Miletich I, Sharpe PT, Shivdasani RA
published in: Developmental cell
information resource reference: The stomach mesenchymal transcription factor Barx1 specifies gastric epithelial identity through inhibition of transient Wnt signaling. Dev Cell. 2005 Apr; 8(4):611-22.
journal title abbreviation: Dev Cell
publication date: 2005-04-01T00:00:00
year: 2005
type: Academic Article
type: Article
type: Document
type: Information Resource

Trps1, a regulator of chondrocyte proliferation and differentiation, interacts with the activator form of Gli3.
PubMed Identifier: 19389374
author list: Wuelling M, Kaiser FJ, Buelens LA, Braunholz D, Shivdasani RA, Depping R, Vortkamp A
published in: Developmental biology
information resource reference: Trps1, a regulator of chondrocyte proliferation and differentiation, interacts with the activator form of Gli3. Dev Biol. 2009 Apr 01; 328(1):40-53.
journal title abbreviation: Dev Biol
publication date: 2009-01-14T00:00:00
year: 2009
type: Academic Article
type: Article
type: Document
type: Information Resource

HLA homozygosity and shared HLA haplotypes in the development of transfusion-associated graft-versus-host disease.
PubMed Identifier: 7866271
author list: Shivdasani RA, Anderson KC
published in: Leukemia & lymphoma
information resource reference: HLA homozygosity and shared HLA haplotypes in the development of transfusion-associated graft-versus-host disease. Leuk Lymphoma. 1994 Oct; 15(3-4):227-34.
journal title abbreviation: Leuk Lymphoma
publication date: 1994-10-01T00:00:00
year: 1994
type: Academic Article
type: Article
type: Document
type: Information Resource

Regulation of the serum concentration of thrombopoietin in thrombocytopenic NF-E2 knockout mice.
PubMed Identifier: 9292514
author list: Shivdasani RA, Fielder P, Keller GA, Orkin SH, de Sauvage FJ
published in: Blood
information resource reference: Regulation of the serum concentration of thrombopoietin in thrombocytopenic NF-E2 knockout mice. Blood. 1997 Sep 01; 90(5):1821-7.
journal title abbreviation: Blood
publication date: 1997-09-01T00:00:00
year: 1997
type: Academic Article
type: Article
type: Document
type: Information Resource

Action of the Caenorhabditis elegans GATA factor END-1 in Xenopus suggests that similar mechanisms initiate endoderm development in ecdysozoa and vertebrates.
PubMed Identifier: 10760276
author list: Shoichet SA, Malik TH, Rothman JH, Shivdasani RA
published in: Proceedings of the National Academy of Sciences of the United States of America
information resource reference: Action of the Caenorhabditis elegans GATA factor END-1 in Xenopus suggests that similar mechanisms initiate endoderm development in ecdysozoa and vertebrates. Proc Natl Acad Sci U S A. 2000 Apr 11; 97(8):4076-81.
journal title abbreviation: Proc Natl Acad Sci U S A
publication date: 2000-04-11T00:00:00
year: 2000
type: Academic Article
type: Article
type: Document
type: Information Resource

Cellular and molecular biology of megakaryocyte differentiation in the absence of lineage-restricted transcription factors.
PubMed Identifier: 11012181
author list: Lecine P, Shivdasani RA
published in: Stem cells (Dayton, Ohio)
information resource reference: Cellular and molecular biology of megakaryocyte differentiation in the absence of lineage-restricted transcription factors. Stem Cells. 1998; 16 Suppl 2:91-5.
journal title abbreviation: Stem Cells
publication date: 1998-01-01T00:00:00
year: 1998
type: Academic Article
type: Article
type: Document
type: Information Resource

Wnt signaling in gut organogenesis.
PubMed Identifier: 19279719
author list: Verzi MP, Shivdasani RA
published in: Organogenesis
information resource reference: Wnt signaling in gut organogenesis. Organogenesis. 2008 Apr; 4(2):87-91.
journal title abbreviation: Organogenesis
publication date: 2008-04-01T00:00:00
year: 2008
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 101887
type: Authorship
author rank in publication: 2
linked author: Shivdasani, Ramesh
linked information resource: Stem cells: The intestinal-crypt casino.

The 8q24 cancer risk variant rs6983267 shows long-range interaction with MYC in colorectal cancer.
PubMed Identifier: 19561607
author list: Pomerantz MM, Ahmadiyeh N, Jia L, Herman P, Verzi MP, Doddapaneni H, Beckwith CA, Chan JA, Hills A, Davis M, Yao K, Kehoe SM, Lenz HJ, Haiman CA, Yan C, Henderson BE, Frenkel B, Barretina J, Bass A, Tabernero J, Baselga J, Regan MM, Manak JR, Shivdasani R, Coetzee GA, Freedman ML
published in: Nature genetics
information resource reference: The 8q24 cancer risk variant rs6983267 shows long-range interaction with MYC in colorectal cancer. Nat Genet. 2009 Aug; 41(8):882-4.
journal title abbreviation: Nat Genet
publication date: 2009-06-28T00:00:00
year: 2009
type: Academic Article
type: Article
type: Document
type: Information Resource

Expression analysis of primary mouse megakaryocyte differentiation and its application in identifying stage-specific molecular markers and a novel transcriptional target of NF-E2.
PubMed Identifier: 17047147
author list: Chen Z, Hu M, Shivdasani RA
published in: Blood
information resource reference: Expression analysis of primary mouse megakaryocyte differentiation and its application in identifying stage-specific molecular markers and a novel transcriptional target of NF-E2. Blood. 2007 Feb 15; 109(4):1451-9.
journal title abbreviation: Blood
publication date: 2006-10-17T00:00:00
year: 2006
type: Academic Article
type: Article
type: Document
type: Information Resource

Regulation of platelet biogenesis: insights from the May-Hegglin anomaly and other MYH9-related disorders.
PubMed Identifier: 19630815
author list: Chen Z, Shivdasani RA
published in: Journal of thrombosis and haemostasis : JTH
information resource reference: Regulation of platelet biogenesis: insights from the May-Hegglin anomaly and other MYH9-related disorders. J Thromb Haemost. 2009 Jul; 7 Suppl 1:272-6.
journal title abbreviation: J Thromb Haemost
publication date: 2009-07-01T00:00:00
year: 2009
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 110301
type: Authorship
author rank in publication: 3
linked author: Shivdasani, Ramesh
linked information resource: Blood platelets are assembled principally at the ends of proplatelet processes produced by differentiated megakaryocytes.

Activation of ERBB2 signaling causes resistance to the EGFR-directed therapeutic antibody cetuximab.
PubMed Identifier: 21900593
author list: Yonesaka K, Zejnullahu K, Okamoto I, Satoh T, Cappuzzo F, Souglakos J, Ercan D, Rogers A, Roncalli M, Takeda M, Fujisaka Y, Philips J, Shimizu T, Maenishi O, Cho Y, Sun J, Destro A, Taira K, Takeda K, Okabe T, Swanson J, Itoh H, Takada M, Lifshits E, Okuno K, Engelman JA, Shivdasani RA, Nishio K, Fukuoka M, Varella-Garcia M, Nakagawa K, Jänne PA
published in: Science translational medicine
information resource reference: Activation of ERBB2 signaling causes resistance to the EGFR-directed therapeutic antibody cetuximab. Sci Transl Med. 2011 Sep 07; 3(99):99ra86.
journal title abbreviation: Sci Transl Med
publication date: 2011-09-07T00:00:00
year: 2011
type: Academic Article
type: Article
type: Document
type: Information Resource

Antigen recognition by T lymphocytes: Three cases for two receptors
author list: Thomas DW, Betancourt S, Kim KH, Shivdasani RA, Solvay MJ, Taylor CM, Nairn R
published in: In: Sercarz E, Berzofsky J, editors. Immunogenicity of protein antigen: Repertoire and regulation.
information resource reference: Antigen recognition by T lymphocytes: Three cases for two receptors. In: Sercarz E, Berzofsky J, editors. Immunogenicity of protein antigen: Repertoire and regulation. 1987; 67-73.
publication date: 1987-01-01T00:00:00
year: 1987
type: Academic Article
type: Article
type: Document
type: Information Resource

High-resolution analysis of genetic alterations in small bowel carcinoid tumors reveals areas of recurrent amplification and loss.
PubMed Identifier: 18383209
author list: Kulke MH, Freed E, Chiang DY, Philips J, Zahrieh D, Glickman JN, Shivdasani RA
published in: Genes, chromosomes & cancer
information resource reference: High-resolution analysis of genetic alterations in small bowel carcinoid tumors reveals areas of recurrent amplification and loss. Genes Chromosomes Cancer. 2008 Jul; 47(7):591-603.
journal title abbreviation: Genes Chromosomes Cancer
publication date: 2008-07-01T00:00:00
year: 2008
type: Academic Article
type: Article
type: Document
type: Information Resource

The microtubule modulator RanBP10 plays a critical role in regulation of platelet discoid shape and degranulation.
PubMed Identifier: 19801445
author list: Kunert S, Meyer I, Fleischhauer S, Wannack M, Fiedler J, Shivdasani RA, Schulze H
published in: Blood
information resource reference: The microtubule modulator RanBP10 plays a critical role in regulation of platelet discoid shape and degranulation. Blood. 2009 Dec 24; 114(27):5532-40.
journal title abbreviation: Blood
publication date: 2009-10-02T00:00:00
year: 2009
type: Academic Article
type: Article
type: Document
type: Information Resource

Megakaryocytes and beyond: the birth of platelets.
PubMed Identifier: 12871316
author list: Italiano JE, Shivdasani RA
published in: Journal of thrombosis and haemostasis : JTH
information resource reference: Megakaryocytes and beyond: the birth of platelets. J Thromb Haemost. 2003 Jun; 1(6):1174-82.
journal title abbreviation: J Thromb Haemost
publication date: 2003-06-01T00:00:00
year: 2003
type: Academic Article
type: Article
type: Document
type: Information Resource

A role for Rab27b in NF-E2-dependent pathways of platelet formation.
PubMed Identifier: 12907454
author list: Tiwari S, Italiano JE, Barral DC, Mules EH, Novak EK, Swank RT, Seabra MC, Shivdasani RA
published in: Blood
information resource reference: A role for Rab27b in NF-E2-dependent pathways of platelet formation. Blood. 2003 Dec 01; 102(12):3970-9.
journal title abbreviation: Blood
publication date: 2003-08-07T00:00:00
year: 2003
type: Academic Article
type: Article
type: Document
type: Information Resource

A lineage-restricted and divergent beta-tubulin isoform is essential for the biogenesis, structure and function of blood platelets.
PubMed Identifier: 11369202
author list: Schwer HD, Lecine P, Tiwari S, Italiano JE, Hartwig JH, Shivdasani RA
published in: Current biology : CB
information resource reference: A lineage-restricted and divergent beta-tubulin isoform is essential for the biogenesis, structure and function of blood platelets. Curr Biol. 2001 Apr 17; 11(8):579-86.
journal title abbreviation: Curr Biol
publication date: 2001-04-17T00:00:00
year: 2001
type: Academic Article
type: Article
type: Document
type: Information Resource

Regulation of megakaryocyte and erythroid differentiation by NF-E2
author list: Kim SW, Shivdasani RV
published in: In: Licht J, Ravid K, editors. Trancription factors: Normal and malignant development of blood cells.
information resource reference: Regulation of megakaryocyte and erythroid differentiation by NF-E2. In: Licht J, Ravid K, editors. Trancription factors: Normal and malignant development of blood cells. 2001; 13-29.
publication date: 2001-01-01T00:00:00
year: 2001
type: Academic Article
type: Article
type: Document
type: Information Resource

Transfusion-associated graft-versus-host disease
author list: Shivdasani RA, Anderson KC
published in: In: Petz LD, Swisher S, Kleinman S, Spence R, Strauss R, editors. Clinical practice of transfusion medicine.
information resource reference: Transfusion-associated graft-versus-host disease. In: Petz LD, Swisher S, Kleinman S, Spence R, Strauss R, editors. Clinical practice of transfusion medicine. 1995; 931-46.
publication date: 1995-01-01T00:00:00
year: 1995
type: Academic Article
type: Article
type: Document
type: Information Resource

Absence of blood formation in mice lacking the T-cell leukaemia oncoprotein tal-1/SCL.
PubMed Identifier: 7830794
author list: Shivdasani RA, Mayer EL, Orkin SH
published in: Nature
information resource reference: Absence of blood formation in mice lacking the T-cell leukaemia oncoprotein tal-1/SCL. Nature. 1995 Feb 02; 373(6513):432-4.
journal title abbreviation: Nature
publication date: 1995-02-02T00:00:00
year: 1995
type: Academic Article
type: Article
type: Document
type: Information Resource

A Fli in the ointment
author list: Shivdasani RA
published in: Blood
information resource reference: A Fli in the ointment. Blood. 2005; 105:9-10.
publication date: 2005-01-01T00:00:00
year: 2005
type: Academic Article
type: Article
type: Document
type: Information Resource

Targeting PI3K signaling as a therapeutic approach for colorectal cancer.
PubMed Identifier: 21723986
author list: Zhang J, Roberts TM, Shivdasani RA
published in: Gastroenterology
information resource reference: Targeting PI3K signaling as a therapeutic approach for colorectal cancer. Gastroenterology. 2011 Jul; 141(1):50-61.
journal title abbreviation: Gastroenterology
publication date: 2011-07-01T00:00:00
year: 2011
type: Academic Article
type: Article
type: Document
type: Information Resource

Boundaries, junctions and transitions in the gastrointestinal tract.
PubMed Identifier: 21802415
author list: San Roman AK, Shivdasani RA
published in: Experimental cell research
information resource reference: Boundaries, junctions and transitions in the gastrointestinal tract. Exp Cell Res. 2011 Nov 15; 317(19):2711-8.
journal title abbreviation: Exp Cell Res
publication date: 2011-07-23T00:00:00
year: 2011
type: Academic Article
type: Article
type: Document
type: Information Resource

Mechanisms of organelle transport and capture along proplatelets during platelet production.
PubMed Identifier: 16118320
author list: Richardson JL, Shivdasani RA, Boers C, Hartwig JH, Italiano JE
published in: Blood
information resource reference: Mechanisms of organelle transport and capture along proplatelets during platelet production. Blood. 2005 Dec 15; 106(13):4066-75.
journal title abbreviation: Blood
publication date: 2005-08-23T00:00:00
year: 2005
type: Academic Article
type: Article
type: Document
type: Information Resource

Monoclonal antibodies define the characteristics and cellular distribution of an Ia-associated protein.
PubMed Identifier: 2312130
author list: Shivdasani RA, Esch TR, Chen GH, Thomas DW
published in: Hybridoma
information resource reference: Monoclonal antibodies define the characteristics and cellular distribution of an Ia-associated protein. Hybridoma. 1990 Feb; 9(1):17-30.
journal title abbreviation: Hybridoma
publication date: 1990-02-01T00:00:00
year: 1990
type: Academic Article
type: Article
type: Document
type: Information Resource

Requirement of the tissue-restricted homeodomain transcription factor Nkx6.3 in differentiation of gastrin-producing G cells in the stomach antrum.
PubMed Identifier: 18347062
author list: Choi MY, Romer AI, Wang Y, Wu MP, Ito S, Leiter AB, Shivdasani RA
published in: Molecular and cellular biology
information resource reference: Requirement of the tissue-restricted homeodomain transcription factor Nkx6.3 in differentiation of gastrin-producing G cells in the stomach antrum. Mol Cell Biol. 2008 May; 28(10):3208-18.
journal title abbreviation: Mol Cell Biol
publication date: 2008-03-17T00:00:00
year: 2008
type: Academic Article
type: Article
type: Document
type: Information Resource

Barx1-mediated inhibition of Wnt signaling in the mouse thoracic foregut controls tracheo-esophageal septation and epithelial differentiation.
PubMed Identifier: 21799872
author list: Woo J, Miletich I, Kim BM, Sharpe PT, Shivdasani RA
published in: PloS one
information resource reference: Barx1-mediated inhibition of Wnt signaling in the mouse thoracic foregut controls tracheo-esophageal septation and epithelial differentiation. PLoS One. 2011; 6(7):e22493.
journal title abbreviation: PLoS One
publication date: 2011-07-22T00:00:00
year: 2011
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1084733
type: Authorship
author rank in publication: 1
linked author: Shivdasani, Ramesh
linked information resource: Limited gut cell repertoire for multiple hormones.

Limited gut cell repertoire for multiple hormones.
PubMed Identifier: 30038256
author list: Shivdasani RA
published in: Nature cell biology
information resource reference: Limited gut cell repertoire for multiple hormones. Nat Cell Biol. 2018 08; 20(8):865-867.
journal title abbreviation: Nat Cell Biol
publication date: 2018-08-01T00:00:00
year: 2018
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 112918
type: Authorship
author rank in publication: 5
linked author: Shivdasani, Ramesh
linked information resource: Hematopoietic-specific beta 1 tubulin participates in a pathway of platelet biogenesis dependent on the transcription factor NF-E2.

Platelets contribute to postnatal occlusion of the ductus arteriosus.
PubMed Identifier: 19966813
author list: Echtler K, Stark K, Lorenz M, Kerstan S, Walch A, Jennen L, Rudelius M, Seidl S, Kremmer E, Emambokus NR, von Bruehl ML, Frampton J, Isermann B, Genzel-Boroviczény O, Schreiber C, Mehilli J, Kastrati A, Schwaiger M, Shivdasani RA, Massberg S
published in: Nature medicine
information resource reference: Platelets contribute to postnatal occlusion of the ductus arteriosus. Nat Med. 2010 Jan; 16(1):75-82.
journal title abbreviation: Nat Med
publication date: 2009-12-06T00:00:00
year: 2009
type: Academic Article
type: Article
type: Document
type: Information Resource

Tricho-rhino-phalangeal syndrome with supernumerary teeth.
PubMed Identifier: 18946009
author list: Kantaputra P, Miletich I, Lüdecke HJ, Suzuki EY, Praphanphoj V, Shivdasani R, Wuelling M, Vortkamp A, Napierala D, Sharpe PT
published in: Journal of dental research
information resource reference: Tricho-rhino-phalangeal syndrome with supernumerary teeth. J Dent Res. 2008 Nov; 87(11):1027-31.
journal title abbreviation: J Dent Res
publication date: 2008-11-01T00:00:00
year: 2008
type: Academic Article
type: Article
type: Document
type: Information Resource

SOX2 is an amplified lineage-survival oncogene in lung and esophageal squamous cell carcinomas.
PubMed Identifier: 19801978
author list: Bass AJ, Watanabe H, Mermel CH, Yu S, Perner S, Verhaak RG, Kim SY, Wardwell L, Tamayo P, Gat-Viks I, Ramos AH, Woo MS, Weir BA, Getz G, Beroukhim R, O'Kelly M, Dutt A, Rozenblatt-Rosen O, Dziunycz P, Komisarof J, Chirieac LR, Lafargue CJ, Scheble V, Wilbertz T, Ma C, Rao S, Nakagawa H, Stairs DB, Lin L, Giordano TJ, Wagner P, Minna JD, Gazdar AF, Zhu CQ, Brose MS, Cecconello I, Ribeiro U, Marie SK, Dahl O, Shivdasani RA, Tsao MS, Rubin MA, Wong KK, Regev A, Hahn WC, Beer DG, Rustgi AK, Meyerson M
published in: Nature genetics
information resource reference: SOX2 is an amplified lineage-survival oncogene in lung and esophageal squamous cell carcinomas. Nat Genet. 2009 Nov; 41(11):1238-42.
journal title abbreviation: Nat Genet
publication date: 2009-10-04T00:00:00
year: 2009
type: Academic Article
type: Article
type: Document
type: Information Resource

Stem cells: The intestinal-crypt casino.
PubMed Identifier: 20981089
author list: Verzi MP, Shivdasani RA
published in: Nature
information resource reference: Stem cells: The intestinal-crypt casino. Nature. 2010 Oct 28; 467(7319):1055-6.
journal title abbreviation: Nature
publication date: 2010-10-28T00:00:00
year: 2010
type: Academic Article
type: Article
type: Document
type: Information Resource

Molecular mechanisms of megakaryocyte differentiation and platelet production
author list: Schulze H, Shivdasani RA
published in: Sem Thromb Hemost
information resource reference: Molecular mechanisms of megakaryocyte differentiation and platelet production. Sem Thromb Hemost. 2004; 30:389-98.
publication date: 2004-01-01T00:00:00
year: 2004
type: Academic Article
type: Article
type: Document
type: Information Resource

Transcription factors in megakaryocyte differentiation and gene expression
author list: Shivdasani RA
published in: In: Hunt P, Kuter D, Sheridan W, Zucker-Franklin D, editors. Thrombopoiesis and thrombopoietins.
information resource reference: Transcription factors in megakaryocyte differentiation and gene expression. In: Hunt P, Kuter D, Sheridan W, Zucker-Franklin D, editors. Thrombopoiesis and thrombopoietins. 1997; 189-202.
publication date: 1997-01-01T00:00:00
year: 1997
type: Academic Article
type: Article
type: Document
type: Information Resource

TCF4 and CDX2, major transcription factors for intestinal function, converge on the same cis-regulatory regions.
PubMed Identifier: 20696899
author list: Verzi MP, Hatzis P, Sulahian R, Philips J, Schuijers J, Shin H, Freed E, Lynch JP, Dang DT, Brown M, Clevers H, Liu XS, Shivdasani RA
published in: Proceedings of the National Academy of Sciences of the United States of America
information resource reference: TCF4 and CDX2, major transcription factors for intestinal function, converge on the same cis-regulatory regions. Proc Natl Acad Sci U S A. 2010 Aug 24; 107(34):15157-62.
journal title abbreviation: Proc Natl Acad Sci U S A
publication date: 2010-08-09T00:00:00
year: 2010
type: Academic Article
type: Article
type: Document
type: Information Resource

Uncoupling of chondrocyte differentiation and perichondrial mineralization underlies the skeletal dysplasia in tricho-rhino-phalangeal syndrome.
PubMed Identifier: 18424451
author list: Napierala D, Sam K, Morello R, Zheng Q, Munivez E, Shivdasani RA, Lee B
published in: Human molecular genetics
information resource reference: Uncoupling of chondrocyte differentiation and perichondrial mineralization underlies the skeletal dysplasia in tricho-rhino-phalangeal syndrome. Hum Mol Genet. 2008 Jul 15; 17(14):2244-54.
journal title abbreviation: Hum Mol Genet
publication date: 2008-04-17T00:00:00
year: 2008
type: Academic Article
type: Article
type: Document
type: Information Resource

Molecular associations of IA antigens after T-B cell interactions. I. Identification of new molecular associations.
PubMed Identifier: 2456348
author list: Shivdasani RA, Thomas DW
published in: Journal of immunology (Baltimore, Md. : 1950)
information resource reference: Molecular associations of IA antigens after T-B cell interactions. I. Identification of new molecular associations. J Immunol. 1988 Aug 15; 141(4):1252-60.
journal title abbreviation: J Immunol
publication date: 1988-08-15T00:00:00
year: 1988
type: Academic Article
type: Article
type: Document
type: Information Resource

Regulation of mouse stomach development and Barx1 expression by specific microRNAs.
PubMed Identifier: 21307095
author list: Kim BM, Woo J, Kanellopoulou C, Shivdasani RA
published in: Development (Cambridge, England)
information resource reference: Regulation of mouse stomach development and Barx1 expression by specific microRNAs. Development. 2011 Mar; 138(6):1081-6.
journal title abbreviation: Development
publication date: 2011-02-09T00:00:00
year: 2011
type: Academic Article
type: Article
type: Document
type: Information Resource

Notch signaling in stomach epithelial stem cell homeostasis.
PubMed Identifier: 21402740
author list: Kim TH, Shivdasani RA
published in: The Journal of experimental medicine
information resource reference: Notch signaling in stomach epithelial stem cell homeostasis. J Exp Med. 2011 Apr 11; 208(4):677-88.
journal title abbreviation: J Exp Med
publication date: 2011-03-14T00:00:00
year: 2011
type: Academic Article
type: Article
type: Document
type: Information Resource

Genomic analysis identifies association of Fusobacterium with colorectal carcinoma.
PubMed Identifier: 22009990
author list: Kostic AD, Gevers D, Pedamallu CS, Michaud M, Duke F, Earl AM, Ojesina AI, Jung J, Bass AJ, Tabernero J, Baselga J, Liu C, Shivdasani RA, Ogino S, Birren BW, Huttenhower C, Garrett WS, Meyerson M
published in: Genome research
information resource reference: Genomic analysis identifies association of Fusobacterium with colorectal carcinoma. Genome Res. 2012 Feb; 22(2):292-8.
journal title abbreviation: Genome Res
publication date: 2011-10-18T00:00:00
year: 2011
type: Academic Article
type: Article
type: Document
type: Information Resource

Stem cell niches: famished Paneth cells, gluttonous stem cells.
PubMed Identifier: 22835795
author list: Kim TH, Shivdasani RA
published in: Current biology : CB
information resource reference: Stem cell niches: famished Paneth cells, gluttonous stem cells. Curr Biol. 2012 Jul 24; 22(14):R579-80.
journal title abbreviation: Curr Biol
publication date: 2012-07-24T00:00:00
year: 2012
type: Academic Article
type: Article
type: Document
type: Information Resource

Erythropoiesis and globin gene expression in mice lacking the transcription factor NF-E2.
PubMed Identifier: 7567998
author list: Shivdasani RA, Orkin SH
published in: Proceedings of the National Academy of Sciences of the United States of America
information resource reference: Erythropoiesis and globin gene expression in mice lacking the transcription factor NF-E2. Proc Natl Acad Sci U S A. 1995 Sep 12; 92(19):8690-4.
journal title abbreviation: Proc Natl Acad Sci U S A
publication date: 1995-09-12T00:00:00
year: 1995
type: Academic Article
type: Article
type: Document
type: Information Resource

Intermediate lymphocytic lymphoma: clinical and pathologic features of a recently characterized subtype of non-Hodgkin's lymphoma.
PubMed Identifier: 8478674
author list: Shivdasani RA, Hess JL, Skarin AT, Pinkus GS
published in: Journal of clinical oncology : official journal of the American Society of Clinical Oncology
information resource reference: Intermediate lymphocytic lymphoma: clinical and pathologic features of a recently characterized subtype of non-Hodgkin's lymphoma. J Clin Oncol. 1993 Apr; 11(4):802-111.
journal title abbreviation: J Clin Oncol
publication date: 1993-04-01T00:00:00
year: 1993
type: Academic Article
type: Article
type: Document
type: Information Resource

Prominin1 (CD133) as an intestinal stem cell marker: promise and nuance.
PubMed Identifier: 19409288
author list: Montgomery RK, Shivdasani RA
published in: Gastroenterology
information resource reference: Prominin1 (CD133) as an intestinal stem cell marker: promise and nuance. Gastroenterology. 2009 Jun; 136(7):2051-4.
journal title abbreviation: Gastroenterology
publication date: 2009-05-03T00:00:00
year: 2009
type: Academic Article
type: Article
type: Document
type: Information Resource

Profiling critical cancer gene mutations in clinical tumor samples.
PubMed Identifier: 19924296
author list: MacConaill LE, Campbell CD, Kehoe SM, Bass AJ, Hatton C, Niu L, Davis M, Yao K, Hanna M, Mondal C, Luongo L, Emery CM, Baker AC, Philips J, Goff DJ, Fiorentino M, Rubin MA, Polyak K, Chan J, Wang Y, Fletcher JA, Santagata S, Corso G, Roviello F, Shivdasani R, Kieran MW, Ligon KL, Stiles CD, Hahn WC, Meyerson ML, Garraway LA
published in: PloS one
information resource reference: Profiling critical cancer gene mutations in clinical tumor samples. PLoS One. 2009 Nov 18; 4(11):e7887.
journal title abbreviation: PLoS One
publication date: 2009-11-18T00:00:00
year: 2009
type: Academic Article
type: Article
type: Document
type: Information Resource

Hedgehog signaling controls mesenchymal growth in the developing mammalian digestive tract.
PubMed Identifier: 20430747
author list: Mao J, Kim BM, Rajurkar M, Shivdasani RA, McMahon AP
published in: Development (Cambridge, England)
information resource reference: Hedgehog signaling controls mesenchymal growth in the developing mammalian digestive tract. Development. 2010 May; 137(10):1721-9.
journal title abbreviation: Development
publication date: 2010-05-01T00:00:00
year: 2010
type: Academic Article
type: Article
type: Document
type: Information Resource

Requirement of the epithelium-specific Ets transcription factor Spdef for mucous gland cell function in the gastric antrum.
PubMed Identifier: 20801882
author list: Horst D, Gu X, Bhasin M, Yang Q, Verzi M, Lin D, Joseph M, Zhang X, Chen W, Li YP, Shivdasani RA, Libermann TA
published in: The Journal of biological chemistry
information resource reference: Requirement of the epithelium-specific Ets transcription factor Spdef for mucous gland cell function in the gastric antrum. J Biol Chem. 2010 Nov 05; 285(45):35047-55.
journal title abbreviation: J Biol Chem
publication date: 2010-08-26T00:00:00
year: 2010
type: Academic Article
type: Article
type: Document
type: Information Resource

Gastrointestinal adenocarcinomas of the esophagus, stomach, and colon exhibit distinct patterns of genome instability and oncogenesis.
PubMed Identifier: 22751462
author list: Dulak AM, Schumacher SE, van Lieshout J, Imamura Y, Fox C, Shim B, Ramos AH, Saksena G, Baca SC, Baselga J, Tabernero J, Barretina J, Enzinger PC, Corso G, Roviello F, Lin L, Bandla S, Luketich JD, Pennathur A, Meyerson M, Ogino S, Shivdasani RA, Beer DG, Godfrey TE, Beroukhim R, Bass AJ
published in: Cancer research
information resource reference: Gastrointestinal adenocarcinomas of the esophagus, stomach, and colon exhibit distinct patterns of genome instability and oncogenesis. Cancer Res. 2012 Sep 01; 72(17):4383-93.
journal title abbreviation: Cancer Res
publication date: 2012-07-02T00:00:00
year: 2012
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1110296
type: Authorship
author rank in publication: 11
linked author: Shivdasani, Ramesh
linked information resource: Enhancer, transcriptional, and cell fate plasticity precedes intestinal determination during endoderm development.

Authorship 1110226
type: Authorship
author rank in publication: 31
linked author: Shivdasani, Ramesh
linked information resource: TRPS1 Is a Lineage-Specific Transcriptional Dependency in Breast Cancer.

Enhancer, transcriptional, and cell fate plasticity precedes intestinal determination during endoderm development.
PubMed Identifier: 30366903
author list: Banerjee KK, Saxena M, Kumar N, Chen L, Cavazza A, Toke NH, O'Neill NK, Madha S, Jadhav U, Verzi MP, Shivdasani RA
published in: Genes & development
information resource reference: Enhancer, transcriptional, and cell fate plasticity precedes intestinal determination during endoderm development. Genes Dev. 2018 11 01; 32(21-22):1430-1442.
journal title abbreviation: Genes Dev
publication date: 2018-10-26T00:00:00
year: 2018
type: Academic Article
type: Article
type: Document
type: Information Resource

TRPS1 Is a Lineage-Specific Transcriptional Dependency in Breast Cancer.
PubMed Identifier: 30380416
author list: Witwicki RM, Ekram MB, Qiu X, Janiszewska M, Shu S, Kwon M, Trinh A, Frias E, Ramadan N, Hoffman G, Yu K, Xie Y, McAllister G, McDonald R, Golji J, Schlabach M, deWeck A, Keen N, Chan HM, Ruddy D, Rejtar T, Sovath S, Silver S, Sellers WR, Jagani Z, Hogarty MD, Roberts C, Brown M, Stegmaier K, Long H, Shivdasani RA, Pellman D, Polyak K
published in: Cell reports
information resource reference: TRPS1 Is a Lineage-Specific Transcriptional Dependency in Breast Cancer. Cell Rep. 2018 10 30; 25(5):1255-1267.e5.
journal title abbreviation: Cell Rep
publication date: 2018-10-30T00:00:00
year: 2018
type: Academic Article
type: Article
type: Document
type: Information Resource

Structure and expression of a novel frizzled gene isolated from the developing mouse gut.
PubMed Identifier: 10903145
author list: Malik TH, Shivdasani RA
published in: The Biochemical journal
information resource reference: Structure and expression of a novel frizzled gene isolated from the developing mouse gut. Biochem J. 2000 Aug 01; 349 Pt 3:829-34.
journal title abbreviation: Biochem J
publication date: 2000-08-01T00:00:00
year: 2000
type: Academic Article
type: Article
type: Document
type: Information Resource

The May-Hegglin anomaly gene MYH9 is a negative regulator of platelet biogenesis modulated by the Rho-ROCK pathway.
PubMed Identifier: 17392504
author list: Chen Z, Naveiras O, Balduini A, Mammoto A, Conti MA, Adelstein RS, Ingber D, Daley GQ, Shivdasani RA
published in: Blood
information resource reference: The May-Hegglin anomaly gene MYH9 is a negative regulator of platelet biogenesis modulated by the Rho-ROCK pathway. Blood. 2007 Jul 01; 110(1):171-9.
journal title abbreviation: Blood
publication date: 2007-03-28T00:00:00
year: 2007
type: Academic Article
type: Article
type: Document
type: Information Resource

Independent functions and mechanisms for homeobox gene Barx1 in patterning mouse stomach and spleen.
PubMed Identifier: 17855428
author list: Kim BM, Miletich I, Mao J, McMahon AP, Sharpe PA, Shivdasani RA
published in: Development (Cambridge, England)
information resource reference: Independent functions and mechanisms for homeobox gene Barx1 in patterning mouse stomach and spleen. Development. 2007 Oct; 134(20):3603-13.
journal title abbreviation: Development
publication date: 2007-09-12T00:00:00
year: 2007
type: Academic Article
type: Article
type: Document
type: Information Resource

DOT1L-mediated H3K79 methylation in chromatin is dispensable for Wnt pathway-specific and other intestinal epithelial functions.
PubMed Identifier: 23428873
author list: Ho LL, Sinha A, Verzi M, Bernt KM, Armstrong SA, Shivdasani RA
published in: Molecular and cellular biology
information resource reference: DOT1L-mediated H3K79 methylation in chromatin is dispensable for Wnt pathway-specific and other intestinal epithelial functions. Mol Cell Biol. 2013 May; 33(9):1735-45.
journal title abbreviation: Mol Cell Biol
publication date: 2013-02-19T00:00:00
year: 2013
type: Academic Article
type: Article
type: Document
type: Information Resource

The role of methotrexate in the management of steriod-dependent asthma
author list: Coffey MJ, Sanders GM, Eschenbacher WL, Tsien A, Shivdasani RA, Weber RW, Toews GB, McCune JW
published in: Chest
information resource reference: The role of methotrexate in the management of steriod-dependent asthma. Chest. 1994; 105:117-21.
publication date: 1994-01-01T00:00:00
year: 1994
type: Academic Article
type: Article
type: Document
type: Information Resource

Extragonadal germ cell tumors
author list: Shivdasani RA, Kantoff PW
published in: In: Raghavan D, Scher HI, Leibel SA, Lange P, editors. Principles and practice of genitourinary oncology.
information resource reference: Extragonadal germ cell tumors. In: Raghavan D, Scher HI, Leibel SA, Lange P, editors. Principles and practice of genitourinary oncology. 1996; 751-64.
publication date: 1996-01-01T00:00:00
year: 1996
type: Academic Article
type: Article
type: Document
type: Information Resource

Mechanisms of thrombopoiesis.
PubMed Identifier: 16102038
author list: Schulze H, Shivdasani RA
published in: Journal of thrombosis and haemostasis : JTH
information resource reference: Mechanisms of thrombopoiesis. J Thromb Haemost. 2005 Aug; 3(8):1717-24.
journal title abbreviation: J Thromb Haemost
publication date: 2005-08-01T00:00:00
year: 2005
type: Academic Article
type: Article
type: Document
type: Information Resource

Regulation of gene expression with double-stranded phosphorothioate oligonucleotides.
PubMed Identifier: 2237444
author list: Bielinska A, Shivdasani RA, Zhang LQ, Nabel GJ
published in: Science (New York, N.Y.)
information resource reference: Regulation of gene expression with double-stranded phosphorothioate oligonucleotides. Science. 1990 Nov 16; 250(4983):997-1000.
journal title abbreviation: Science
publication date: 1990-11-16T00:00:00
year: 1990
type: Academic Article
type: Article
type: Document
type: Information Resource

Culture, expansion, and differentiation of murine megakaryocytes.
PubMed Identifier: 18432953
author list: Shivdasani RA, Schulze H
published in: Current protocols in immunology
information resource reference: Culture, expansion, and differentiation of murine megakaryocytes. Curr Protoc Immunol. 2005 Jul; Chapter 22:Unit 22F.6.
journal title abbreviation: Curr Protoc Immunol
publication date: 2005-07-01T00:00:00
year: 2005
type: Academic Article
type: Article
type: Document
type: Information Resource

Cell-type selective chromatin remodeling defines the active subset of FOXA1-bound enhancers.
PubMed Identifier: 19129543
author list: Eeckhoute J, Lupien M, Meyer CA, Verzi MP, Shivdasani RA, Liu XS, Brown M
published in: Genome research
information resource reference: Cell-type selective chromatin remodeling defines the active subset of FOXA1-bound enhancers. Genome Res. 2009 Mar; 19(3):372-80.
journal title abbreviation: Genome Res
publication date: 2009-01-07T00:00:00
year: 2009
type: Academic Article
type: Article
type: Document
type: Information Resource

Essential and redundant functions of caudal family proteins in activating adult intestinal genes.
PubMed Identifier: 21402776
author list: Verzi MP, Shin H, Ho LL, Liu XS, Shivdasani RA
published in: Molecular and cellular biology
information resource reference: Essential and redundant functions of caudal family proteins in activating adult intestinal genes. Mol Cell Biol. 2011 May; 31(10):2026-39.
journal title abbreviation: Mol Cell Biol
publication date: 2011-03-14T00:00:00
year: 2011
type: Academic Article
type: Article
type: Document
type: Information Resource

Differential WNT activity in colorectal cancer confers limited tumorigenic potential and is regulated by MAPK signaling.
PubMed Identifier: 22318865
author list: Horst D, Chen J, Morikawa T, Ogino S, Kirchner T, Shivdasani RA
published in: Cancer research
information resource reference: Differential WNT activity in colorectal cancer confers limited tumorigenic potential and is regulated by MAPK signaling. Cancer Res. 2012 Mar 15; 72(6):1547-56.
journal title abbreviation: Cancer Res
publication date: 2012-02-08T00:00:00
year: 2012
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1131289
type: Authorship
author rank in publication: 10
linked author: Shivdasani, Ramesh
linked information resource: The lineage-specific transcription factor CDX2 navigates dynamic chromatin to control distinct stages of intestine development.

The lineage-specific transcription factor CDX2 navigates dynamic chromatin to control distinct stages of intestine development.
PubMed Identifier: 30745430
author list: Kumar N, Tsai YH, Chen L, Zhou A, Banerjee KK, Saxena M, Huang S, Toke NH, Xing J, Shivdasani RA, Spence JR, Verzi MP
published in: Development (Cambridge, England)
information resource reference: The lineage-specific transcription factor CDX2 navigates dynamic chromatin to control distinct stages of intestine development. Development. 2019 03 01; 146(5).
journal title abbreviation: Development
publication date: 2019-03-01T00:00:00
year: 2019
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1134793
type: Authorship
author rank in publication: 2
linked author: Shivdasani, Ramesh
linked information resource: Dissecting Cell Lineages: From Microscope to Kaleidoscope.

Dissecting Cell Lineages: From Microscope to Kaleidoscope.
PubMed Identifier: 30794779
author list: Jadhav U, Shivdasani RA
published in: Cell
information resource reference: Dissecting Cell Lineages: From Microscope to Kaleidoscope. Cell. 2019 02 21; 176(5):949-951.
journal title abbreviation: Cell
publication date: 2019-02-21T00:00:00
year: 2019
type: Academic Article
type: Article
type: Document
type: Information Resource

Intestines
MeSH DescriptorUI: D007422
MeSH semantic group name: Anatomy
number of authors: 873
number of publications: 1982
uniqueness weight: 0.508395
type: Concept

Megakaryocytes
MeSH DescriptorUI: D008533
MeSH semantic group name: Anatomy
number of authors: 187
number of publications: 567
uniqueness weight: 0.722556
type: Concept

Intestinal Mucosa
MeSH DescriptorUI: D007413
MeSH semantic group name: Anatomy
number of authors: 1033
number of publications: 3213
uniqueness weight: 0.43647
type: Concept

Authorship 1141743
type: Authorship
author rank in publication: 11
linked author: Shivdasani, Ramesh
linked information resource: Extensive Recovery of Embryonic Enhancer and Gene Memory Stored in Hypomethylated Enhancer DNA.

Extensive Recovery of Embryonic Enhancer and Gene Memory Stored in Hypomethylated Enhancer DNA.
PubMed Identifier: 30905509
author list: Jadhav U, Cavazza A, Banerjee KK, Xie H, O'Neill NK, Saenz-Vash V, Herbert Z, Madha S, Orkin SH, Zhai H, Shivdasani RA
published in: Molecular cell
information resource reference: Extensive Recovery of Embryonic Enhancer and Gene Memory Stored in Hypomethylated Enhancer DNA. Mol Cell. 2019 05 02; 74(3):542-554.e5.
journal title abbreviation: Mol Cell
publication date: 2019-03-21T00:00:00
year: 2019
type: Academic Article
type: Article
type: Document
type: Information Resource

Stem Cells
MeSH DescriptorUI: D013234
MeSH semantic group name: Anatomy
number of authors: 1378
number of publications: 3602
uniqueness weight: 0.393432
type: Concept

Stem Cell Niche
MeSH DescriptorUI: D055153
MeSH semantic group name: Anatomy
number of authors: 222
number of publications: 378
uniqueness weight: 0.756355
type: Concept

Genetics
type: Department
type: Organization

Medicine
type: Department
type: Organization

Pathology
type: Department
type: Organization

Pediatrics
type: Department
type: Organization

Stem Cell and Regenerative Biology
type: Department
type: Organization

Surgery
type: Department
type: Organization

Hematology/Oncology
type: Division
type: Organization

Rheumatology
type: Division
type: Organization

Adult Oncology
type: Division
type: Organization

Oncology
type: Division
type: Organization

Brigham and Women's Hospital
type: Organization

Boston Children's Hospital
type: Organization

Dana-Farber Cancer Institute
type: Organization

Harvard Medical School
type: Organization

Italiano, Joseph
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Singh, Harshabad
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first name: Harshabad
last name: Singh
full name: Harshabad Singh, M.B.,B.S.
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person in primary position: Assistant Professor of Medicine
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Development and vascularity of intestinal mesenchyme
end date: 2028-04-30
principal investigator name: SHIVDASANI, RAMESH A
start date: 2019-06-01
type: Grant
sponsor award id: R01DK121540

Principal Investigator
type: Researcher Role
researcher role of: Shivdasani, Ramesh
contributes to: Development and vascularity of intestinal mesenchyme

Orkin, Stuart
eCommons Login: SHO1
first name: Stuart
last name: Orkin
full name: Stuart Holland Orkin, M.D.
has faculty rank: Full Professor
latitude: 42.33789600000000
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person in primary position: David G. Nathan Distinguished Professor of Pediatrics
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Daley, George
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Ivanov, Pavel
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Liao, Katherine
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last name: Liao
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preferred title: Associate Professor of Medicine

Walensky, Loren
eCommons Login: LDW1
first name: Loren
last name: Walensky
full name: Loren David Walensky, M.D.,Ph.D.
has faculty rank: Full Professor
latitude: 42.33729300000000
longitude: -71.10763500000000
Person ID: 55069
person in primary position: Professor of Pediatrics
type: Agent
type: Person
preferred title: Professor of Pediatrics

Zon, Leonard
eCommons Login: LIZ1
first name: Leonard
last name: Zon
full name: Leonard Ira Zon, M.D.
has faculty rank: Full Professor
latitude: 42.33743600000000
longitude: -71.10544700000000
Person ID: 60887
person in primary position: Professor of Stem Cell and Regenerative Biology and Grousbeck Professor of Pediatrics, Harvard Medical School
type: Agent
type: Person
preferred title: Professor of Stem Cell and Regenerative Biology and Grousbeck Professor of Pediatrics, Harvard Medical School

Perrimon, Norbert
eCommons Login: NP7
first name: Norbert
last name: Perrimon
full name: Norbert Perrimon, Ph.D.
has faculty rank: Full Professor
latitude: 42.33837200000000
longitude: -71.10326900000000
Person ID: 6247
person in primary position: James Stillman Professor of Developmental Biology
type: Agent
type: Person
preferred title: James Stillman Professor of Developmental Biology

Authorship 127629
type: Authorship
author rank in publication: 2
linked author: Shivdasani, Ramesh
linked information resource: Prominin1 (CD133) as an intestinal stem cell marker: promise and nuance.

Zhao, Jean
eCommons Login: JJZ1
first name: Jean
last name: Zhao
full name: Jean J. Zhao, Ph.D.
has faculty rank: Full Professor
latitude: 42.33729300000000
longitude: -71.10763500000000
Person ID: 81549
person in primary position: Professor of Biological Chemistry and Molecular Pharmacology
type: Agent
type: Person
preferred title: Professor of Biological Chemistry and Molecular Pharmacology

Authorship 1168432
type: Authorship
author rank in publication: 27
linked author: Shivdasani, Ramesh
linked information resource: Enhancer signatures stratify and predict outcomes of non-functional pancreatic neuroendocrine tumors.

Enhancer signatures stratify and predict outcomes of non-functional pancreatic neuroendocrine tumors.
PubMed Identifier: 31263286
author list: Cejas P, Drier Y, Dreijerink KMA, Brosens LAA, Deshpande V, Epstein CB, Conemans EB, Morsink FHM, Graham MK, Valk GD, Vriens MR, Castillo CF, Ferrone CR, Adar T, Bowden M, Whitton HJ, Da Silva A, Font-Tello A, Long HW, Gaskell E, Shoresh N, Heaphy CM, Sicinska E, Kulke MH, Chung DC, Bernstein BE, Shivdasani RA
published in: Nature medicine
information resource reference: Enhancer signatures stratify and predict outcomes of non-functional pancreatic neuroendocrine tumors. Nat Med. 2019 08; 25(8):1260-1265.
journal title abbreviation: Nat Med
publication date: 2019-07-01T00:00:00
year: 2019
type: Academic Article
type: Article
type: Document
type: Information Resource

Nandi, Bisweswar
eCommons Login: BN18
first name: Bisweswar
last name: Nandi
full name: Bisweswar Nandi, Ph.D.
has faculty rank: Instructor
latitude: 42.33729300000000
longitude: -71.10763500000000
Person ID: 10645
person in primary position: Instructor in Surgery
type: Agent
type: Person
preferred title: Instructor in Surgery

Authorship 137509
type: Authorship
author rank in publication: 4
linked author: Shivdasani, Ramesh
linked information resource: Genetics and diet regulate vitamin A production via the homeobox transcription factor ISX.

Authorship 1189161
type: Authorship
author rank in publication: 27
linked author: Shivdasani, Ramesh
linked information resource: Publisher Correction: Enhancer signatures stratify and predict outcomes of non-functional pancreatic neuroendocrine tumors.

Publisher Correction: Enhancer signatures stratify and predict outcomes of non-functional pancreatic neuroendocrine tumors.
PubMed Identifier: 31501535
author list: Cejas P, Drier Y, Dreijerink KMA, Brosens LAA, Deshpande V, Epstein CB, Conemans EB, Morsink FHM, Graham MK, Valk GD, Vriens MR, Castillo CF, Ferrone CR, Adar T, Bowden M, Whitton HJ, Da Silva A, Font-Tello A, Long HW, Gaskell E, Shoresh N, Heaphy CM, Sicinska E, Kulke MH, Chung DC, Bernstein BE, Shivdasani RA
published in: Nature medicine
information resource reference: Publisher Correction: Enhancer signatures stratify and predict outcomes of non-functional pancreatic neuroendocrine tumors. Nat Med. 2019 Oct; 25(10):1627.
journal title abbreviation: Nat Med
publication date: 2019-10-01T00:00:00
year: 2019
type: Academic Article
type: Article
type: Document
type: Information Resource

Professor of Medicine
is primary position: true
position in department: Medicine
position in division: Adult Oncology
sort order: 1
type: Position
HR job title: Professor of Medicine
position in organization: Dana-Farber Cancer Institute

Authorship 139858
type: Authorship
author rank in publication: 2
linked author: Shivdasani, Ramesh
linked information resource: Structure and expression of a novel frizzled gene isolated from the developing mouse gut.

Authorship 1209577
type: Authorship
author rank in publication: 7
linked author: Shivdasani, Ramesh
linked information resource: Krüppel-like Factor 5 Regulates Stemness, Lineage Specification, and Regeneration of Intestinal Epithelial Stem Cells.

Krüppel-like Factor 5 Regulates Stemness, Lineage Specification, and Regeneration of Intestinal Epithelial Stem Cells.
PubMed Identifier: 31778829
author list: Kim CK, Saxena M, Maharjan K, Song JJ, Shroyer KR, Bialkowska AB, Shivdasani RA, Yang VW
published in: Cellular and molecular gastroenterology and hepatology
information resource reference: Krüppel-like Factor 5 Regulates Stemness, Lineage Specification, and Regeneration of Intestinal Epithelial Stem Cells. Cell Mol Gastroenterol Hepatol. 2020; 9(4):587-609.
journal title abbreviation: Cell Mol Gastroenterol Hepatol
publication date: 2019-11-25T00:00:00
year: 2019
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 117001
type: Authorship
author rank in publication: 2
linked author: Shivdasani, Ramesh
linked information resource: Anion exchanger 1 (band 3) is required to prevent erythrocyte membrane surface loss but not to form the membrane skeleton.

Authorship 1223407
type: Authorship
author rank in publication: 8
linked author: Shivdasani, Ramesh
linked information resource: Replicational Dilution of H3K27me3 in Mammalian Cells and the Role of Poised Promoters.

Replicational Dilution of H3K27me3 in Mammalian Cells and the Role of Poised Promoters.
PubMed Identifier: 32027840
author list: Jadhav U, Manieri E, Nalapareddy K, Madha S, Chakrabarti S, Wucherpfennig K, Barefoot M, Shivdasani RA
published in: Molecular cell
information resource reference: Replicational Dilution of H3K27me3 in Mammalian Cells and the Role of Poised Promoters. Mol Cell. 2020 04 02; 78(1):141-151.e5.
journal title abbreviation: Mol Cell
publication date: 2020-02-05T00:00:00
year: 2020
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1225829
type: Authorship
author rank in publication: 15
linked author: Shivdasani, Ramesh
linked information resource: Distinct Mesenchymal Cell Populations Generate the Essential Intestinal BMP Signaling Gradient.

Authorship 1226182
type: Authorship
author rank in publication: 10
linked author: Shivdasani, Ramesh
linked information resource: Ascl2-Dependent Cell Dedifferentiation Drives Regeneration of Ablated Intestinal Stem Cells.

Distinct Mesenchymal Cell Populations Generate the Essential Intestinal BMP Signaling Gradient.
PubMed Identifier: 32084389
author list: McCarthy N, Manieri E, Storm EE, Saadatpour A, Luoma AM, Kapoor VN, Madha S, Gaynor LT, Cox C, Keerthivasan S, Wucherpfennig K, Yuan GC, de Sauvage FJ, Turley SJ, Shivdasani RA
published in: Cell stem cell
information resource reference: Distinct Mesenchymal Cell Populations Generate the Essential Intestinal BMP Signaling Gradient. Cell Stem Cell. 2020 03 05; 26(3):391-402.e5.
journal title abbreviation: Cell Stem Cell
publication date: 2020-02-20T00:00:00
year: 2020
type: Academic Article
type: Article
type: Document
type: Information Resource

Ascl2-Dependent Cell Dedifferentiation Drives Regeneration of Ablated Intestinal Stem Cells.
PubMed Identifier: 32084390
author list: Murata K, Jadhav U, Madha S, van Es J, Dean J, Cavazza A, Wucherpfennig K, Michor F, Clevers H, Shivdasani RA
published in: Cell stem cell
information resource reference: Ascl2-Dependent Cell Dedifferentiation Drives Regeneration of Ablated Intestinal Stem Cells. Cell Stem Cell. 2020 03 05; 26(3):377-390.e6.
journal title abbreviation: Cell Stem Cell
publication date: 2020-02-20T00:00:00
year: 2020
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1234157
type: Authorship
author rank in publication: 11
linked author: Shivdasani, Ramesh
linked information resource: Hedgehog-Activated Fat4 and PCP Pathways Mediate Mesenchymal Cell Clustering and Villus Formation in Gut Development.

Hedgehog-Activated Fat4 and PCP Pathways Mediate Mesenchymal Cell Clustering and Villus Formation in Gut Development.
PubMed Identifier: 32155439
author list: Rao-Bhatia A, Zhu M, Yin WC, Coquenlorge S, Zhang X, Woo J, Sun Y, Dean CH, Liu A, Hui CC, Shivdasani RA, McNeill H, Hopyan S, Kim TH
published in: Developmental cell
information resource reference: Hedgehog-Activated Fat4 and PCP Pathways Mediate Mesenchymal Cell Clustering and Villus Formation in Gut Development. Dev Cell. 2020 03 09; 52(5):647-658.e6.
journal title abbreviation: Dev Cell
publication date: 2020-03-09T00:00:00
year: 2020
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 125266
type: Authorship
author rank in publication: 7
linked author: Shivdasani, Ramesh
linked information resource: Visualization of microtubule growth in living platelets reveals a dynamic marginal band with multiple microtubules.

Authorship 191513
type: Authorship
author rank in publication: 9
linked author: Shivdasani, Ramesh
linked information resource: The May-Hegglin anomaly gene MYH9 is a negative regulator of platelet biogenesis modulated by the Rho-ROCK pathway.

Authorship 130879
type: Authorship
author rank in publication: 1
linked author: Shivdasani, Ramesh
linked information resource: Brief report: graft-versus-host disease associated with transfusion of blood from unrelated HLA-homozygous donors.

Authorship 134996
type: Authorship
author rank in publication: 1
linked author: Shivdasani, Ramesh
linked information resource: Transfusion-associated graft-versus-host disease: scratching the surface.

Authorship 1265321
type: Authorship
author rank in publication: 2
linked author: Shivdasani, Ramesh
linked information resource: Epigenetic regulation of intestinal stem cell differentiation.

Epigenetic regulation of intestinal stem cell differentiation.
PubMed Identifier: 32628072
author list: Verzi MP, Shivdasani RA
published in: American journal of physiology. Gastrointestinal and liver physiology
information resource reference: Epigenetic regulation of intestinal stem cell differentiation. Am J Physiol Gastrointest Liver Physiol. 2020 08 01; 319(2):G189-G196.
journal title abbreviation: Am J Physiol Gastrointest Liver Physiol
publication date: 2020-07-06T00:00:00
year: 2020
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 160872
type: Authorship
author rank in publication: 6
linked author: Shivdasani, Ramesh
linked information resource: DOT1L-mediated H3K79 methylation in chromatin is dispensable for Wnt pathway-specific and other intestinal epithelial functions.

Authorship 165445
type: Authorship
author rank in publication: 10
linked author: Shivdasani, Ramesh
linked information resource: Dynamic visualization of thrombopoiesis within bone marrow.

Authorship 1282167
type: Authorship
author rank in publication: 3
linked author: Shivdasani, Ramesh
linked information resource: Cellular and molecular architecture of the intestinal stem cell niche.

Cellular and molecular architecture of the intestinal stem cell niche.
PubMed Identifier: 32884148
author list: McCarthy N, Kraiczy J, Shivdasani RA
published in: Nature cell biology
information resource reference: Cellular and molecular architecture of the intestinal stem cell niche. Nat Cell Biol. 2020 09; 22(9):1033-1041.
journal title abbreviation: Nat Cell Biol
publication date: 2020-09-03T00:00:00
year: 2020
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 203178
type: Authorship
author rank in publication: 2
linked author: Shivdasani, Ramesh
linked information resource: Wnt signaling in gut organogenesis.

BCMP
type: Department
type: Organization

Authorship 14024
type: Authorship
author rank in publication: 2
linked author: Shivdasani, Ramesh
linked information resource: Boundaries, junctions and transitions in the gastrointestinal tract.

Authorship 1307453
type: Authorship
author rank in publication: 2
linked author: Shivdasani, Ramesh
linked information resource: Epigenetic Signatures and Plasticity of Intestinal and Other Stem Cells.

Epigenetic Signatures and Plasticity of Intestinal and Other Stem Cells.
PubMed Identifier: 33234018
author list: Saxena M, Shivdasani RA
published in: Annual review of physiology
information resource reference: Epigenetic Signatures and Plasticity of Intestinal and Other Stem Cells. Annu Rev Physiol. 2021 02 10; 83:405-427.
journal title abbreviation: Annu Rev Physiol
publication date: 2020-11-24T00:00:00
year: 2020
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 210175
type: Authorship
author rank in publication: 1
linked author: Shivdasani, Ramesh
linked information resource: Absence of blood formation in mice lacking the T-cell leukaemia oncoprotein tal-1/SCL.

Authorship 1314213
type: Authorship
author rank in publication: 13
linked author: Shivdasani, Ramesh
linked information resource: Progastrin production transitions from Bmi1+/Prox1+ to Lgr5high cells during early intestinal tumorigenesis.

Progastrin production transitions from Bmi1+/Prox1+ to Lgr5high cells during early intestinal tumorigenesis.
PubMed Identifier: 33360299
author list: Giraud J, Foroutan M, Boubaker-Vitre J, Grillet F, Homayed Z, Jadhav U, Crespy P, Breuker C, Bourgaux JF, Hazerbroucq J, Pignodel C, Brulin B, Shivdasani RA, Jay P, Hollande F, Pannequin J
published in: Translational oncology
information resource reference: Progastrin production transitions from Bmi1+/Prox1+ to Lgr5high cells during early intestinal tumorigenesis. Transl Oncol. 2021 Feb; 14(2):101001.
journal title abbreviation: Transl Oncol
publication date: 2020-12-23T00:00:00
year: 2020
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1331521
type: Authorship
author rank in publication: 1
linked author: Shivdasani, Ramesh
linked information resource: Tissue regeneration: Reserve or reverse?

Tissue regeneration: Reserve or reverse?
PubMed Identifier: 33602845
author list: Shivdasani RA, Clevers H, de Sauvage FJ
published in: Science (New York, N.Y.)
information resource reference: Tissue regeneration: Reserve or reverse? Science. 2021 Feb 19; 371(6531):784-786.
journal title abbreviation: Science
publication date: 2021-02-19T00:00:00
year: 2021
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1335305
type: Authorship
author rank in publication: 18
linked author: Shivdasani, Ramesh
linked information resource: Adaptation of pancreatic cancer cells to nutrient deprivation is reversible and requires glutamine synthetase stabilization by mTORC1.

Adaptation of pancreatic cancer cells to nutrient deprivation is reversible and requires glutamine synthetase stabilization by mTORC1.
PubMed Identifier: 33653947
author list: Tsai PY, Lee MS, Jadhav U, Naqvi I, Madha S, Adler A, Mistry M, Naumenko S, Lewis CA, Hitchcock DS, Roberts FR, DelNero P, Hank T, Honselmann KC, Morales Oyarvide V, Mino-Kenudson M, Clish CB, Shivdasani RA, Kalaany NY
published in: Proceedings of the National Academy of Sciences of the United States of America
information resource reference: Adaptation of pancreatic cancer cells to nutrient deprivation is reversible and requires glutamine synthetase stabilization by mTORC1. Proc Natl Acad Sci U S A. 2021 03 09; 118(10).
journal title abbreviation: Proc Natl Acad Sci U S A
publication date: 2021-03-09T00:00:00
year: 2021
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1338303
type: Authorship
author rank in publication: 7
linked author: Shivdasani, Ramesh
linked information resource: Creb5 establishes the competence for Prg4 expression in articular cartilage.

Creb5 establishes the competence for Prg4 expression in articular cartilage.
PubMed Identifier: 33712729
author list: Zhang CH, Gao Y, Jadhav U, Hung HH, Holton KM, Grodzinsky AJ, Shivdasani RA, Lassar AB
published in: Communications biology
information resource reference: Creb5 establishes the competence for Prg4 expression in articular cartilage. Commun Biol. 2021 03 12; 4(1):332.
journal title abbreviation: Commun Biol
publication date: 2021-03-12T00:00:00
year: 2021
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1363105
type: Authorship
author rank in publication: 10
linked author: Shivdasani, Ramesh
linked information resource: Hybrid Stomach-Intestinal Chromatin States Underlie Human Barrett's Metaplasia.

Hybrid Stomach-Intestinal Chromatin States Underlie Human Barrett's Metaplasia.
PubMed Identifier: 34090884
author list: Singh H, Ha K, Hornick JL, Madha S, Cejas P, Jajoo K, Singh P, Polak P, Lee H, Shivdasani RA
published in: Gastroenterology
information resource reference: Hybrid Stomach-Intestinal Chromatin States Underlie Human Barrett's Metaplasia. Gastroenterology. 2021 09; 161(3):924-939.e11.
journal title abbreviation: Gastroenterology
publication date: 2021-06-04T00:00:00
year: 2021
type: Academic Article
type: Article
type: Document
type: Information Resource

Instructor in Surgery
is primary position: true
position in department: Surgery
position in division: https://connects.catalyst.harvard.edu/Profiles/profile/1229413
sort order: 1
type: Position
HR job title: Instructor in Surgery
position in organization: Brigham and Women's Hospital

Authorship 1383185
type: Authorship
author rank in publication: 1
linked author: Shivdasani, Ramesh
linked information resource: Race to the bottom: Darwinian competition in early intestinal tumorigenesis.

Race to the bottom: Darwinian competition in early intestinal tumorigenesis.
PubMed Identifier: 34358438
author list: Shivdasani RA
published in: Cell stem cell
information resource reference: Race to the bottom: Darwinian competition in early intestinal tumorigenesis. Cell Stem Cell. 2021 08 05; 28(8):1340-1342.
journal title abbreviation: Cell Stem Cell
publication date: 2021-08-05T00:00:00
year: 2021
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1398778
type: Authorship
author rank in publication: 24
linked author: Shivdasani, Ramesh
linked information resource: SATB2 preserves colon stem cell identity and mediates ileum-colon conversion via enhancer remodeling.

SATB2 preserves colon stem cell identity and mediates ileum-colon conversion via enhancer remodeling.
PubMed Identifier: 34582804
author list: Gu W, Wang H, Huang X, Kraiczy J, Singh PNP, Ng C, Dagdeviren S, Houghton S, Pellon-Cardenas O, Lan Y, Nie Y, Zhang J, Banerjee KK, Onufer EJ, Warner BW, Spence J, Scherl E, Rafii S, Lee RT, Verzi MP, Redmond D, Longman R, Helin K, Shivdasani RA, Zhou Q
published in: Cell stem cell
information resource reference: SATB2 preserves colon stem cell identity and mediates ileum-colon conversion via enhancer remodeling. Cell Stem Cell. 2022 01 06; 29(1):101-115.e10.
journal title abbreviation: Cell Stem Cell
publication date: 2021-09-27T00:00:00
year: 2021
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 185093
type: Authorship
author rank in publication: 6
linked author: Shivdasani, Ramesh
linked information resource: Differential WNT activity in colorectal cancer confers limited tumorigenic potential and is regulated by MAPK signaling.

Bhattacharya, Swarnabh
eCommons Login: swb415
first name: Swarnabh
last name: Bhattacharya
full name: Swarnabh Bhattacharya, Ph.D.
has faculty rank: Instructor
Person ID: 201817
person in primary position: Instructor in Medicine
type: Agent
type: Person
preferred title: Instructor in Medicine

Stem cell responses to stretch and strain.
PubMed Identifier: 34801376
author list: Bhattacharya S, Wolfenson H, Shivdasani R, Shalom-Feuerstein R
published in: Trends in cell biology
information resource reference: Stem cell responses to stretch and strain. Trends Cell Biol. 2022 01; 32(1):4-7.
journal title abbreviation: Trends Cell Biol
publication date: 2021-11-17T00:00:00
year: 2021
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1412172
type: Authorship
author rank in publication: 3
linked author: Shivdasani, Ramesh
linked information resource: Stem cell responses to stretch and strain.

Authorship 1414718
type: Authorship
author rank in publication: 2
linked author: Shivdasani, Ramesh
linked information resource: The hens guarding epithelial cancer fox-houses.

The hens guarding epithelial cancer fox-houses.
PubMed Identifier: 34845342
author list: Gaynor LT, Shivdasani RA
published in: Cell research
information resource reference: The hens guarding epithelial cancer fox-houses. Cell Res. 2022 03; 32(3):225-226.
journal title abbreviation: Cell Res
publication date: 2022-03-01T00:00:00
year: 2022
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1422990
type: Authorship
author rank in publication: 15
linked author: Shivdasani, Ramesh
linked information resource: Transcription factor-mediated intestinal metaplasia and the role of a shadow enhancer.

Transcription factor-mediated intestinal metaplasia and the role of a shadow enhancer.
PubMed Identifier: 34969824
author list: Singh H, Seruggia D, Madha S, Saxena M, Nagaraja AK, Wu Z, Zhou J, Huebner AJ, Maglieri A, Wezenbeek J, Hochedlinger K, Orkin SH, Bass AJ, Hornick JL, Shivdasani RA
published in: Genes & development
information resource reference: Transcription factor-mediated intestinal metaplasia and the role of a shadow enhancer. Genes Dev. 2022 01 01; 36(1-2):38-52.
journal title abbreviation: Genes Dev
publication date: 2021-12-30T00:00:00
year: 2021
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1466837
type: Authorship
author rank in publication: 4
linked author: Shivdasani, Ramesh
linked information resource: Cell and chromatin transitions in intestinal stem cell regeneration.

Cell and chromatin transitions in intestinal stem cell regeneration.
PubMed Identifier: 35738677
author list: Singh PNP, Madha S, Leiter AB, Shivdasani RA
published in: Genes & development
information resource reference: Cell and chromatin transitions in intestinal stem cell regeneration. Genes Dev. 2022 06 01; 36(11-12):684-698.
journal title abbreviation: Genes Dev
publication date: 2022-06-01T00:00:00
year: 2022
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 461475
type: Authorship
author rank in publication: 2
linked author: Shivdasani, Ramesh
linked information resource: Regulation of platelet biogenesis: insights from the May-Hegglin anomaly and other MYH9-related disorders.

Authorship 1526622
type: Authorship
author rank in publication: 12
linked author: Shivdasani, Ramesh
linked information resource: Defining the structure, signals, and cellular elements of the gastric mesenchymal niche.

Defining the structure, signals, and cellular elements of the gastric mesenchymal niche.
PubMed Identifier: 36798304
author list: Manieri E, Tie G, Seruggia D, Madha S, Maglieri A, Huang K, Fujiwara Y, Zhang K, Orkin SH, He R, McCarthy N, Shivdasani RA
published in: bioRxiv : the preprint server for biology
information resource reference: Defining the structure, signals, and cellular elements of the gastric mesenchymal niche. bioRxiv. 2023 Feb 24.
journal title abbreviation: bioRxiv
publication date: 2023-02-24T00:00:00
year: 2023
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 180276
type: Authorship
author rank in publication: 1
linked author: Shivdasani, Ramesh
linked information resource: Regulation of the serum concentration of thrombopoietin in thrombocytopenic NF-E2 knockout mice.

Assistant Professor of Medicine
is primary position: true
position in department: Medicine
position in division: Oncology
sort order: 1
type: Position
HR job title: Assistant Professor of Medicine
position in organization: Dana-Farber Cancer Institute

Authorship 1531389
type: Authorship
author rank in publication: 7
linked author: Shivdasani, Ramesh
linked information resource: Smooth muscle contributes to the development and function of a layered intestinal stem cell niche.

Smooth muscle contributes to the development and function of a layered intestinal stem cell niche.
PubMed Identifier: 36924771
author list: McCarthy N, Tie G, Madha S, He R, Kraiczy J, Maglieri A, Shivdasani RA
published in: Developmental cell
information resource reference: Smooth muscle contributes to the development and function of a layered intestinal stem cell niche. Dev Cell. 2023 04 10; 58(7):550-564.e6.
journal title abbreviation: Dev Cell
publication date: 2023-03-15T00:00:00
year: 2023
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 182371
type: Authorship
author rank in publication: 11
linked author: Shivdasani, Ramesh
linked information resource: Requirement of the epithelium-specific Ets transcription factor Spdef for mucous gland cell function in the gastric antrum.

Authorship 255998
type: Authorship
author rank in publication: 6
linked author: Shivdasani, Ramesh
linked information resource: Mice lacking transcription factor NF-E2 provide in vivo validation of the proplatelet model of thrombocytopoiesis and show a platelet production defect that is intrinsic to megakaryocytes.

Authorship 1562495
type: Authorship
author rank in publication: 9
linked author: Shivdasani, Ramesh
linked information resource: Graded BMP signaling within intestinal crypt architecture directs self-organization of the Wnt-secreting stem cell niche.

Graded BMP signaling within intestinal crypt architecture directs self-organization of the Wnt-secreting stem cell niche.
PubMed Identifier: 37028407
author list: Kraiczy J, McCarthy N, Malagola E, Tie G, Madha S, Boffelli D, Wagner DE, Wang TC, Shivdasani RA
published in: Cell stem cell
information resource reference: Graded BMP signaling within intestinal crypt architecture directs self-organization of the Wnt-secreting stem cell niche. Cell Stem Cell. 2023 04 06; 30(4):433-449.e8.
journal title abbreviation: Cell Stem Cell
publication date: 2023-04-06T00:00:00
year: 2023
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 31453
type: Authorship
author rank in publication: 2
linked author: Shivdasani, Ramesh
linked information resource: Megakaryocyte-osteoblast interaction revealed in mice deficient in transcription factors GATA-1 and NF-E2.

Authorship 3154
type: Authorship
author rank in publication: 5
linked author: Shivdasani, Ramesh
linked information resource: Trps1, a regulator of chondrocyte proliferation and differentiation, interacts with the activator form of Gli3.

Authorship 337099
type: Authorship
author rank in publication: 1
linked author: Shivdasani, Ramesh
linked information resource: The transcriptional control of hematopoiesis.

Professor of Pathology
is primary position: true
position in department: Pathology
position in division: https://connects.catalyst.harvard.edu/Profiles/profile/1229413
sort order: 1
type: Position
HR job title: Professor of Pathology
position in organization: Brigham and Women's Hospital

Associate Professor of Medicine
is primary position: true
position in department: Medicine
position in division: Rheumatology
sort order: 1
type: Position
HR job title: Associate Professor of Medicine
position in organization: Brigham and Women's Hospital

Professor of Pediatrics
is primary position: true
position in department: Pediatrics
position in division: Hematology/Oncology
sort order: 1
type: Position
HR job title: Professor of Pediatrics
position in organization: Dana-Farber Cancer Institute

Authorship 423200
type: Authorship
author rank in publication: 3
linked author: Shivdasani, Ramesh
linked information resource: Erythroid maturation and globin gene expression in mice with combined deficiency of NF-E2 and nrf-2.

Authorship 1608903
type: Authorship
author rank in publication: 14
linked author: Shivdasani, Ramesh
linked information resource: Role of PDGFRA+ cells and a CD55+ PDGFRALo fraction in the gastric mesenchymal niche.

Authorship 1609758
type: Authorship
author rank in publication: 12
linked author: Shivdasani, Ramesh
linked information resource: Cochlear organoids reveal transcriptional programs of postnatal hair cell differentiation from supporting cells.

Cochlear organoids reveal transcriptional programs of postnatal hair cell differentiation from supporting cells.
PubMed Identifier: 37952154
author list: Kalra G, Lenz D, Abdul-Aziz D, Hanna C, Basu M, Herb BR, Colantuoni C, Milon B, Saxena M, Shetty AC, Hertzano R, Shivdasani RA, Ament SA, Edge ASB
published in: Cell reports
information resource reference: Cochlear organoids reveal transcriptional programs of postnatal hair cell differentiation from supporting cells. Cell Rep. 2023 11 28; 42(11):113421.
journal title abbreviation: Cell Rep
publication date: 2023-11-11T00:00:00
year: 2023
type: Academic Article
type: Article
type: Document
type: Information Resource

Role of PDGFRA+ cells and a CD55+ PDGFRALo fraction in the gastric mesenchymal niche.
PubMed Identifier: 38042929
author list: Manieri E, Tie G, Malagola E, Seruggia D, Madha S, Maglieri A, Huang K, Fujiwara Y, Zhang K, Orkin SH, Wang TC, He R, McCarthy N, Shivdasani RA
published in: Nature communications
information resource reference: Role of PDGFRA+ cells and a CD55+ PDGFRALo fraction in the gastric mesenchymal niche. Nat Commun. 2023 12 02; 14(1):7978.
journal title abbreviation: Nat Commun
publication date: 2023-12-02T00:00:00
year: 2023
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 502012
type: Authorship
author rank in publication: 7
linked author: Shivdasani, Ramesh
linked information resource: Differential roles of microtubule assembly and sliding in proplatelet formation by megakaryocytes.

Authorship 1623154
type: Authorship
author rank in publication: 14
linked author: Shivdasani, Ramesh
linked information resource: Transcription factor dynamics, oscillation, and functions in human enteroendocrine cell differentiation.

Transcription factor dynamics, oscillation, and functions in human enteroendocrine cell differentiation.
PubMed Identifier: 38260422
author list: Singh PNP, Gu W, Madha S, Lynch AW, Cejas P, He R, Bhattacharya S, Gomez MM, Oser MG, Brown M, Long HW, Meyer CA, Zhou Q, Shivdasani RA
published in: bioRxiv : the preprint server for biology
information resource reference: Transcription factor dynamics, oscillation, and functions in human enteroendocrine cell differentiation. bioRxiv. 2024 Jan 09.
journal title abbreviation: bioRxiv
publication date: 2024-01-09T00:00:00
year: 2024
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 583741
type: Authorship
linked author: Shivdasani, Ramesh
linked information resource: High-resolution analysis of genetic alterations in small bowel carcinoid tumors reveals areas of recurrent amplification and loss

Authorship 249741
type: Authorship
author rank in publication: 2
linked author: Shivdasani, Ramesh
linked information resource: A "knockdown" mutation created by cis-element gene targeting reveals the dependence of erythroid cell maturation on the level of transcription factor GATA-1.

Authorship 1651654
type: Authorship
author rank in publication: 14
linked author: Shivdasani, Ramesh
linked information resource: Transcription factor dynamics, oscillation, and functions in human enteroendocrine cell differentiation.

Authorship 1652040
type: Authorship
author rank in publication: 11
linked author: Shivdasani, Ramesh
linked information resource: A MTA2-SATB2 chromatin complex restrains colonic plasticity toward small intestine by retaining HNF4A at colonic chromatin.

Transcription factor dynamics, oscillation, and functions in human enteroendocrine cell differentiation.
PubMed Identifier: 38733993
author list: Singh PNP, Gu W, Madha S, Lynch AW, Cejas P, He R, Bhattacharya S, Muñoz Gomez M, Oser MG, Brown M, Long HW, Meyer CA, Zhou Q, Shivdasani RA
published in: Cell stem cell
information resource reference: Transcription factor dynamics, oscillation, and functions in human enteroendocrine cell differentiation. Cell Stem Cell. 2024 Jul 05; 31(7):1038-1057.e11.
journal title abbreviation: Cell Stem Cell
publication date: 2024-05-10T00:00:00
year: 2024
type: Academic Article
type: Article
type: Document
type: Information Resource

A MTA2-SATB2 chromatin complex restrains colonic plasticity toward small intestine by retaining HNF4A at colonic chromatin.
PubMed Identifier: 38678016
author list: Gu W, Huang X, Singh PNP, Li S, Lan Y, Deng M, Lacko LA, Gomez-Salinero JM, Rafii S, Verzi MP, Shivdasani RA, Zhou Q
published in: Nature communications
information resource reference: A MTA2-SATB2 chromatin complex restrains colonic plasticity toward small intestine by retaining HNF4A at colonic chromatin. Nat Commun. 2024 Apr 27; 15(1):3595.
journal title abbreviation: Nat Commun
publication date: 2024-04-27T00:00:00
year: 2024
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 313872
type: Authorship
author rank in publication: 3
linked author: Shivdasani, Ramesh
linked information resource: p45 NF-E2 regulates expression of thromboxane synthase in megakaryocytes.

Authorship 415101
type: Authorship
author rank in publication: 4
linked author: Shivdasani, Ramesh
linked information resource: Downregulation of Hedgehog signaling is required for organogenesis of the small intestine in Xenopus.

Authorship 240638
type: Authorship
author rank in publication: 8
linked author: Shivdasani, Ramesh
linked information resource: A Phase II study of gemcitabine and docetaxel in patients with metastatic pancreatic carcinoma.

Research Fellow in Medicine
is primary position: true
position in department: Medicine
position in division: Oncology
sort order: 1
type: Position
HR job title: Research Fellow in Medicine
position in organization: Dana-Farber Cancer Institute

Associate Professor of Medicine
is primary position: true
position in department: Medicine
position in division: Rheumatology
sort order: 1
type: Position
HR job title: Associate Professor of Medicine
position in organization: Brigham and Women's Hospital

Professor of Biological Chemistry and Molecular Pharmacology
is primary position: true
position in department: BCMP
position in division: https://connects.catalyst.harvard.edu/Profiles/profile/1229413
sort order: 1
type: Position
HR job title: Professor of Biological Chemistry and Molecular Pharmacology
position in organization: Dana-Farber Cancer Institute

Authorship 242549
type: Authorship
author rank in publication: 1
linked author: Shivdasani, Ramesh
linked information resource: Erythropoiesis and globin gene expression in mice lacking the transcription factor NF-E2.

Authorship 268103
type: Authorship
author rank in publication: 2
linked author: Shivdasani, Ramesh
linked information resource: Transcription factor GATA-1 in megakaryocyte development.

Authorship 1687334
type: Authorship
author rank in publication: 23
linked author: Shivdasani, Ramesh
linked information resource: Short-term post-fast refeeding enhances intestinal stemness via polyamines.

Short-term post-fast refeeding enhances intestinal stemness via polyamines.
PubMed Identifier: 39169180
author list: Imada S, Khawaled S, Shin H, Meckelmann SW, Whittaker CA, Corrêa RO, Alquati C, Lu Y, Tie G, Pradhan D, Calibasi-Kocal G, Nascentes Melo LM, Allies G, Rösler J, Wittenhofer P, Krystkiewicz J, Schmitz OJ, Roper J, Vinolo MAR, Ricciardiello L, Lien EC, Vander Heiden MG, Shivdasani RA, Cheng CW, Tasdogan A, Yilmaz ÖH
published in: Nature
information resource reference: Short-term post-fast refeeding enhances intestinal stemness via polyamines. Nature. 2024 09; 633(8031):895-904.
journal title abbreviation: Nature
publication date: 2024-08-21T00:00:00
year: 2024
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 655751
type: Authorship
author rank in publication: 5
linked author: Shivdasani, Ramesh
linked information resource: p63-expressing cells are the stem cells of developing prostate, bladder, and colorectal epithelia.

p63-expressing cells are the stem cells of developing prostate, bladder, and colorectal epithelia.
PubMed Identifier: 23620512
author list: Pignon JC, Grisanzio C, Geng Y, Song J, Shivdasani RA, Signoretti S
published in: Proceedings of the National Academy of Sciences of the United States of America
information resource reference: p63-expressing cells are the stem cells of developing prostate, bladder, and colorectal epithelia. Proc Natl Acad Sci U S A. 2013 May 14; 110(20):8105-10.
journal title abbreviation: Proc Natl Acad Sci U S A
publication date: 2013-04-25T00:00:00
year: 2013
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 79947
type: Authorship
author rank in publication: 9
linked author: Shivdasani, Ramesh
linked information resource: Mechanisms and implications of platelet discoid shape.

Authorship 501752
type: Authorship
author rank in publication: 18
linked author: Shivdasani, Ramesh
linked information resource: Prognostic and predictive value of common mutations for treatment response and survival in patients with metastatic colorectal cancer.

Crypt density and recruited enhancers underlie intestinal tumour initiation.
PubMed Identifier: 39778708
author list: Gaynor L, Singh H, Tie G, Badarinath K, Madha S, Mancini A, Bhattacharya S, Hoshino M, de Sauvage FJ, Murata K, Jadhav U, Shivdasani RA
published in: Nature
information resource reference: Crypt density and recruited enhancers underlie intestinal tumour initiation. Nature. 2025 04; 640(8057):231-239.
journal title abbreviation: Nature
publication date: 2025-01-08T00:00:00
year: 2025
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1717627
type: Authorship
author rank in publication: 12
linked author: Shivdasani, Ramesh
linked information resource: Crypt density and recruited enhancers underlie intestinal tumour initiation.

Authorship 245665
type: Authorship
author rank in publication: 10
linked author: Shivdasani, Ramesh
linked information resource: Differentiation-specific histone modifications reveal dynamic chromatin interactions and partners for the intestinal transcription factor CDX2.

Authorship 205883
type: Authorship
author rank in publication: 3
linked author: Shivdasani, Ramesh
linked information resource: Regulation of mammalian epithelial differentiation and intestine development by class I histone deacetylases.

Authorship 155191
type: Authorship
author rank in publication: 6
linked author: Shivdasani, Ramesh
linked information resource: Transcriptional repression and developmental functions of the atypical vertebrate GATA protein TRPS1.

Authorship 263817
type: Authorship
author rank in publication: 6
linked author: Shivdasani, Ramesh
linked information resource: The microtubule modulator RanBP10 plays a critical role in regulation of platelet discoid shape and degranulation.

Authorship 251112
type: Authorship
author rank in publication: 6
linked author: Shivdasani, Ramesh
linked information resource: Independent functions and mechanisms for homeobox gene Barx1 in patterning mouse stomach and spleen.

Authorship 332401
type: Authorship
author rank in publication: 5
linked author: Shivdasani, Ramesh
linked information resource: Complexity of CNC transcription factors as revealed by gene targeting of the Nrf3 locus.

Authorship 342159
type: Authorship
author rank in publication: 13
linked author: Shivdasani, Ramesh
linked information resource: TCF4 and CDX2, major transcription factors for intestinal function, converge on the same cis-regulatory regions.

Authorship 1729845
type: Authorship
author rank in publication: 13
linked author: Shivdasani, Ramesh
linked information resource: Niche-driven phenotypic plasticity and cis-regulatory dynamics of a revised model for intestinal secretory differentiation.

Authorship 1733633
type: Authorship
author rank in publication: 21
linked author: Shivdasani, Ramesh
linked information resource: Dynamic Reprogramming of Stromal Pdgfra-expressing cells during WNT-Mediated Transformation of the Intestinal Epithelium.

Dynamic Reprogramming of Stromal Pdgfra-expressing cells during WNT-Mediated Transformation of the Intestinal Epithelium.
PubMed Identifier: 39896606
author list: Pellon-Cardenas O, Rout P, Hassan S, Fokas E, Ping H, Patel I, Patel J, Plotsker O, Wu A, Kumar R, Akther M, Logerfo A, Wu S, Wagner DE, Boffelli D, Walton KD, Manieri E, Tong K, Spence JR, Bessman NJ, Shivdasani RA, Verzi MP
published in: bioRxiv : the preprint server for biology
information resource reference: Dynamic Reprogramming of Stromal Pdgfra-expressing cells during WNT-Mediated Transformation of the Intestinal Epithelium. bioRxiv. 2025 Jan 25.
journal title abbreviation: bioRxiv
publication date: 2025-01-25T00:00:00
year: 2025
type: Academic Article
type: Article
type: Document
type: Information Resource

Niche-driven phenotypic plasticity and cis-regulatory dynamics of a revised model for intestinal secretory differentiation.
PubMed Identifier: 39975049
author list: Bhattacharya S, Tei G, Singh PNP, Malagola E, Eskiocak O, He R, Kraiczy J, Gu W, Perlov Y, Beyaz S, Wang TC, Zhou Q, Shivdasani RA
published in: bioRxiv : the preprint server for biology
information resource reference: Niche-driven phenotypic plasticity and cis-regulatory dynamics of a revised model for intestinal secretory differentiation. bioRxiv. 2025 Feb 08.
journal title abbreviation: bioRxiv
publication date: 2025-02-08T00:00:00
year: 2025
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 198292
type: Authorship
author rank in publication: 5
linked author: Shivdasani, Ramesh
linked information resource: Intestinal master transcription factor CDX2 controls chromatin access for partner transcription factor binding.

Authorship 694664
type: Authorship
author rank in publication: 42
linked author: Shivdasani, Ramesh
linked information resource: Somatic mutation of CDKN1B in small intestine neuroendocrine tumors.

Somatic mutation of CDKN1B in small intestine neuroendocrine tumors.
PubMed Identifier: 24185511
author list: Francis JM, Kiezun A, Ramos AH, Serra S, Pedamallu CS, Qian ZR, Banck MS, Kanwar R, Kulkarni AA, Karpathakis A, Manzo V, Contractor T, Philips J, Nickerson E, Pho N, Hooshmand SM, Brais LK, Lawrence MS, Pugh T, McKenna A, Sivachenko A, Cibulskis K, Carter SL, Ojesina AI, Freeman S, Jones RT, Voet D, Saksena G, Auclair D, Onofrio R, Shefler E, Sougnez C, Grimsby J, Green L, Lennon N, Meyer T, Caplin M, Chung DC, Beutler AS, Ogino S, Thirlwell C, Shivdasani R, Asa SL, Harris CR, Getz G, Kulke M, Meyerson M
published in: Nature genetics
information resource reference: Somatic mutation of CDKN1B in small intestine neuroendocrine tumors. Nat Genet. 2013 Dec; 45(12):1483-6.
journal title abbreviation: Nat Genet
publication date: 2013-11-03T00:00:00
year: 2013
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1739329
type: Authorship
author rank in publication: 4
linked author: Shivdasani, Ramesh
linked information resource: Remodelling the Colon With Ileal Properties to Treat Short Bowel Syndrome.

Authorship 1747036
type: Authorship
author rank in publication: 14
linked author: Shivdasani, Ramesh
linked information resource: Intestinal secretory differentiation reflects niche-driven phenotypic and epigenetic plasticity of a common signal-responsive terminal cell.

Authorship 1751016
type: Authorship
author rank in publication: 2
linked author: Shivdasani, Ramesh
linked information resource: Epigenetic fluidity meets phenotypic malleability in intestinal epithelial cells.

Epigenetic fluidity meets phenotypic malleability in intestinal epithelial cells.
PubMed Identifier: 40118045
author list: Bhattacharya S, Shivdasani RA
published in: Cell chemical biology
information resource reference: Epigenetic fluidity meets phenotypic malleability in intestinal epithelial cells. Cell Chem Biol. 2025 Mar 20; 32(3):389-391.
journal title abbreviation: Cell Chem Biol
publication date: 2025-03-20T00:00:00
year: 2025
type: Academic Article
type: Article
type: Document
type: Information Resource

Intestinal secretory differentiation reflects niche-driven phenotypic and epigenetic plasticity of a common signal-responsive terminal cell.
PubMed Identifier: 40203837
author list: Bhattacharya S, Tie G, Singh PNP, Malagola E, Eskiocak O, He R, Kraiczy J, Gu W, Perlov Y, Alici-Garipcan A, Beyaz S, Wang TC, Zhou Q, Shivdasani RA
published in: Cell stem cell
information resource reference: Intestinal secretory differentiation reflects niche-driven phenotypic and epigenetic plasticity of a common signal-responsive terminal cell. Cell Stem Cell. 2025 Jun 05; 32(6):952-969.e8.
journal title abbreviation: Cell Stem Cell
publication date: 2025-04-08T00:00:00
year: 2025
type: Academic Article
type: Article
type: Document
type: Information Resource

Remodelling the Colon With Ileal Properties to Treat Short Bowel Syndrome.
PubMed Identifier: 40187662
author list: Liu T, Li S, Múnera JO, Shivdasani RA, Huang X, Zhou Q
published in: Gastroenterology
information resource reference: Remodelling the Colon With Ileal Properties to Treat Short Bowel Syndrome. Gastroenterology. 2025 Aug; 169(2):352-355.e3.
journal title abbreviation: Gastroenterology
publication date: 2025-04-03T00:00:00
year: 2025
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 174209
type: Authorship
author rank in publication: 27
linked author: Shivdasani, Ramesh
linked information resource: Activation of ERBB2 signaling causes resistance to the EGFR-directed therapeutic antibody cetuximab.

James Stillman Professor of Developmental Biology
is primary position: true
position in department: Genetics
position in division: https://connects.catalyst.harvard.edu/Profiles/profile/1229413
sort order: 1
type: Position
HR job title: James Stillman Professor of Developmental Biology
position in organization: Harvard Medical School

Authorship 182116
type: Authorship
author rank in publication: 15
linked author: Shivdasani, Ramesh
linked information resource: Targeted disruption of the BCL9/ß-catenin complex inhibits oncogenic Wnt signaling.

Authorship 278585
type: Authorship
author rank in publication: 2
linked author: Shivdasani, Ramesh
linked information resource: Cellular and molecular biology of megakaryocyte differentiation in the absence of lineage-restricted transcription factors.

Authorship 622807
type: Authorship
linked author: Shivdasani, Ramesh
linked information resource: Culture and in vitro differentiation of murine megakaryocytes

Instructor in Medicine
is primary position: true
position in department: Medicine
position in division: Oncology
sort order: 1
type: Position
HR job title: Instructor in Medicine
position in organization: Dana-Farber Cancer Institute

Authorship 725073
type: Authorship
author rank in publication: 4
linked author: Shivdasani, Ramesh
linked information resource: Wnt secretion from epithelial cells and subepithelial myofibroblasts is not required in the mouse intestinal stem cell niche in vivo.

Authorship 722986
type: Authorship
author rank in publication: 1
linked author: Shivdasani, Ramesh
linked information resource: Radiation redux: reserve intestinal stem cells miss the call to duty.

Authorship 716407
type: Authorship
author rank in publication: 9
linked author: Shivdasani, Ramesh
linked information resource: Broadly permissive intestinal chromatin underlies lateral inhibition and cell plasticity.

Radiation redux: reserve intestinal stem cells miss the call to duty.
PubMed Identifier: 24506878
author list: Shivdasani RA
published in: Cell stem cell
information resource reference: Radiation redux: reserve intestinal stem cells miss the call to duty. Cell Stem Cell. 2014 Feb 06; 14(2):135-6.
journal title abbreviation: Cell Stem Cell
publication date: 2014-02-06T00:00:00
year: 2014
type: Academic Article
type: Article
type: Document
type: Information Resource

Broadly permissive intestinal chromatin underlies lateral inhibition and cell plasticity.
PubMed Identifier: 24413398
author list: Kim TH, Li F, Ferreiro-Neira I, Ho LL, Luyten A, Nalapareddy K, Long H, Verzi M, Shivdasani RA
published in: Nature
information resource reference: Broadly permissive intestinal chromatin underlies lateral inhibition and cell plasticity. Nature. 2014 Feb 27; 506(7489):511-5.
journal title abbreviation: Nature
publication date: 2014-01-12T00:00:00
year: 2014
type: Academic Article
type: Article
type: Document
type: Information Resource

Wnt secretion from epithelial cells and subepithelial myofibroblasts is not required in the mouse intestinal stem cell niche in vivo.
PubMed Identifier: 24527386
author list: San Roman AK, Jayewickreme CD, Murtaugh LC, Shivdasani RA
published in: Stem cell reports
information resource reference: Wnt secretion from epithelial cells and subepithelial myofibroblasts is not required in the mouse intestinal stem cell niche in vivo. Stem Cell Reports. 2014 Feb 11; 2(2):127-34.
journal title abbreviation: Stem Cell Reports
publication date: 2014-01-30T00:00:00
year: 2014
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 182905
type: Authorship
author rank in publication: 5
linked author: Shivdasani, Ramesh
linked information resource: Essential and redundant functions of caudal family proteins in activating adult intestinal genes.

Authorship 234834
type: Authorship
author rank in publication: 1
linked author: Shivdasani, Ramesh
linked information resource: Intermediate lymphocytic lymphoma: clinical and pathologic features of a recently characterized subtype of non-Hodgkin's lymphoma.

Authorship 1793787
type: Authorship
author rank in publication: 2
linked author: Shivdasani, Ramesh
linked information resource: Reply.

Reply.
PubMed Identifier: 41240032
author list: Liu T, Shivdasani RA, Huang X
published in: Gastroenterology
information resource reference: Reply. Gastroenterology. 2026 Jan; 170(1):223-224.
journal title abbreviation: Gastroenterology
publication date: 2025-11-15T00:00:00
year: 2025
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 250513
type: Authorship
author rank in publication: 2
linked author: Shivdasani, Ramesh
linked information resource: Overlapping gene expression in fetal mouse intestine development and human colorectal cancer.

Niche regulation of gastric epithelial cell differentiation
end date: 2031-01-31
principal investigator name: SHIVDASANI, RAMESH A
start date: 2026-04-01
type: Grant
sponsor award id: R01DK142783

Principal Investigator
type: Researcher Role
researcher role of: Shivdasani, Ramesh
contributes to: Niche regulation of gastric epithelial cell differentiation

An integrative analysis reveals functional targets of GATA6 transcriptional regulation in gastric cancer.
PubMed Identifier: 24317510
author list: Sulahian R, Casey F, Shen J, Qian ZR, Shin H, Ogino S, Weir BA, Vazquez F, Liu XS, Hahn WC, Bass AJ, Chan V, Shivdasani RA
published in: Oncogene
information resource reference: An integrative analysis reveals functional targets of GATA6 transcriptional regulation in gastric cancer. Oncogene. 2014 Dec 04; 33(49):5637-48.
journal title abbreviation: Oncogene
publication date: 2013-12-09T00:00:00
year: 2013
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 314540
type: Authorship
author rank in publication: 1
linked author: Shivdasani, Ramesh
linked information resource: GEFs on the RhoAd to a colossal nucleus.

Professor of Stem Cell and Regenerative Biology and Grousbeck Professor of Pediatrics, Harvard Medical School
is primary position: true
position in department: Stem Cell and Regenerative Biology
position in division: https://connects.catalyst.harvard.edu/Profiles/profile/1229413
sort order: 1
type: Position
HR job title: Professor of Stem Cell and Regenerative Biology and Grousbeck Professor of Pediatrics, Harvard Medical School
position in organization: Harvard Medical School

David G. Nathan Distinguished Professor of Pediatrics
is primary position: true
position in department: Pediatrics
position in division: Hematology/Oncology
sort order: 1
type: Position
HR job title: David G. Nathan Distinguished Professor of Pediatrics
position in organization: Boston Children's Hospital

James and Thea Stoneman Associate Professor of Surgery in the Field of Vascular Biology
is primary position: true
position in department: Surgery
position in division: https://connects.catalyst.harvard.edu/Profiles/profile/1229413
sort order: 1
type: Position
HR job title: James and Thea Stoneman Associate Professor of Surgery in the Field of Vascular Biology
position in organization: Boston Children's Hospital

Caroline Shields Walker Professor of Medicine
is primary position: true
position in department: BCMP
position in division: https://connects.catalyst.harvard.edu/Profiles/profile/1229413
sort order: 1
type: Position
HR job title: Caroline Shields Walker Professor of Medicine
position in organization: Harvard Medical School

Authorship 308440
type: Authorship
author rank in publication: 40
linked author: Shivdasani, Ramesh
linked information resource: SOX2 is an amplified lineage-survival oncogene in lung and esophageal squamous cell carcinomas.

Authorship 308781
type: Authorship
author rank in publication: 26
linked author: Shivdasani, Ramesh
linked information resource: CDK8 is a colorectal cancer oncogene that regulates beta-catenin activity.

Dissecting engineered cell types and enhancing cell fate conversion via CellNet.
PubMed Identifier: 25126792
author list: Morris SA, Cahan P, Li H, Zhao AM, San Roman AK, Shivdasani RA, Collins JJ, Daley GQ
published in: Cell
information resource reference: Dissecting engineered cell types and enhancing cell fate conversion via CellNet. Cell. 2014 Aug 14; 158(4):889-902.
journal title abbreviation: Cell
publication date: 2014-08-14T00:00:00
year: 2014
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 483748
type: Authorship
author rank in publication: 3
linked author: Shivdasani, Ramesh
linked information resource: Targeting PI3K signaling as a therapeutic approach for colorectal cancer.

Authorship 746335
type: Authorship
author rank in publication: 6
linked author: Shivdasani, Ramesh
linked information resource: Dissecting engineered cell types and enhancing cell fate conversion via CellNet.

Authorship 747785
type: Authorship
author rank in publication: 4
linked author: Shivdasani, Ramesh
linked information resource: Active enhancers are delineated de novo during hematopoiesis, with limited lineage fidelity among specified primary blood cells.

Authorship 752837
type: Authorship
author rank in publication: 10
linked author: Shivdasani, Ramesh
linked information resource: Indian Hedgehog mediates gastrin-induced proliferation in stomach of adult mice.

Active enhancers are delineated de novo during hematopoiesis, with limited lineage fidelity among specified primary blood cells.
PubMed Identifier: 25128499
author list: Luyten A, Zang C, Liu XS, Shivdasani RA
published in: Genes & development
information resource reference: Active enhancers are delineated de novo during hematopoiesis, with limited lineage fidelity among specified primary blood cells. Genes Dev. 2014 Aug 15; 28(16):1827-39.
journal title abbreviation: Genes Dev
publication date: 2014-08-15T00:00:00
year: 2014
type: Academic Article
type: Article
type: Document
type: Information Resource

Indian Hedgehog mediates gastrin-induced proliferation in stomach of adult mice.
PubMed Identifier: 24859162
author list: Feng R, Aihara E, Kenny S, Yang L, Li J, Varro A, Montrose MH, Shroyer NF, Wang TC, Shivdasani RA, Zavros Y
published in: Gastroenterology
information resource reference: Indian Hedgehog mediates gastrin-induced proliferation in stomach of adult mice. Gastroenterology. 2014 Sep; 147(3):655-666.e9.
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Authorship 352255
type: Authorship
author rank in publication: 6
linked author: Shivdasani, Ramesh
linked information resource: A lineage-restricted and divergent beta-tubulin isoform is essential for the biogenesis, structure and function of blood platelets.

Authorship 397412
type: Authorship
author rank in publication: 8
linked author: Shivdasani, Ramesh
linked information resource: A role for Rab27b in NF-E2-dependent pathways of platelet formation.

Authorship 420591
type: Authorship
author rank in publication: 3
linked author: Shivdasani, Ramesh
linked information resource: Characterization of the hematopoietic transcription factor NF-E2 in primary murine megakaryocytes.

Authorship 774094
type: Authorship
author rank in publication: 13
linked author: Shivdasani, Ramesh
linked information resource: An integrative analysis reveals functional targets of GATA6 transcriptional regulation in gastric cancer.

Authorship 491472
type: Authorship
author rank in publication: 2
linked author: Shivdasani, Ramesh
linked information resource: Gastric epithelial stem cells.

Authorship 536975
type: Authorship
author rank in publication: 6
linked author: Shivdasani, Ramesh
linked information resource: RanBP10 is a cytoplasmic guanine nucleotide exchange factor that modulates noncentrosomal microtubules.

Authorship 777326
type: Authorship
author rank in publication: 5
linked author: Shivdasani, Ramesh
linked information resource: Erratum for Verzi et al., Intestinal Master Transcription Factor CDX2 Controls Chromatin Access for Partner Transcription Factor Binding.

Erratum for Verzi et al., Intestinal Master Transcription Factor CDX2 Controls Chromatin Access for Partner Transcription Factor Binding.
PubMed Identifier: 25535405
author list: Verzi MP, Shin H, San Roman AK, Liu XS, Shivdasani RA
published in: Molecular and cellular biology
information resource reference: Erratum for Verzi et al., Intestinal Master Transcription Factor CDX2 Controls Chromatin Access for Partner Transcription Factor Binding. Mol Cell Biol. 2015 Jan 15; 35(2):496.
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Authorship 627838
type: Authorship
linked author: Shivdasani, Ramesh
linked information resource: The role of methotrexate in the management of steriod-dependent asthma

Authorship 310137
type: Authorship
author rank in publication: 12
linked author: Shivdasani, Ramesh
linked information resource: Insights into developmental mechanisms and cancers in the mammalian intestine derived from serial analysis of gene expression and study of the hepatoma-derived growth factor (HDGF).

Authorship 322997
type: Authorship
author rank in publication: 2
linked author: Shivdasani, Ramesh
linked information resource: Characterization of a novel mammalian Groucho isoform and its role in transcriptional regulation.

Authorship 540269
type: Authorship
author rank in publication: 7
linked author: Shivdasani, Ramesh
linked information resource: Pathophysiology of thrombocytopenia and anemia in mice lacking transcription factor NF-E2.

Authorship 583032
type: Authorship
linked author: Shivdasani, Ramesh
linked information resource: Antigen recognition by T lymphocytes: Three cases for two receptors

Authorship 299132
type: Authorship
author rank in publication: 13
linked author: Shivdasani, Ramesh
linked information resource: Genomic analysis identifies association of Fusobacterium with colorectal carcinoma.

Authorship 173309
type: Authorship
author rank in publication: 6
linked author: Shivdasani, Ramesh
linked information resource: Interactions between the megakaryocyte/platelet-specific beta1 tubulin and the secretory leukocyte protease inhibitor SLPI suggest a role for regulated proteolysis in platelet functions.

Authorship 506423
type: Authorship
author rank in publication: 1
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linked information resource: Science, another culture: an essay after C. P. Snow.

Authorship 381105
type: Authorship
author rank in publication: 1
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linked information resource: Monoclonal antibodies define the characteristics and cellular distribution of an Ia-associated protein.

Authorship 538229
type: Authorship
author rank in publication: 2
linked author: Shivdasani, Ramesh
linked information resource: Two roles for Ia in antigen-specific T lymphocyte activation.

Authorship 94267
type: Authorship
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linked information resource: Stem cell niches: famished Paneth cells, gluttonous stem cells.

Authorship 554224
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linked information resource: Transcription factor NF-E2 is required for platelet formation independent of the actions of thrombopoietin/MGDF in megakaryocyte development.

Authorship 559716
type: Authorship
author rank in publication: 17
linked author: Shivdasani, Ramesh
linked information resource: Loss of the PlagL2 transcription factor affects lacteal uptake of chylomicrons.

Authorship 321370
type: Authorship
author rank in publication: 5
linked author: Shivdasani, Ramesh
linked information resource: Consequences of GATA-1 deficiency in megakaryocytes and platelets.

Authorship 241377
type: Authorship
author rank in publication: 3
linked author: Shivdasani, Ramesh
linked information resource: Intact function of Lgr5 receptor-expressing intestinal stem cells in the absence of Paneth cells.

Authorship 98032
type: Authorship
author rank in publication: 22
linked author: Shivdasani, Ramesh
linked information resource: Gastrointestinal adenocarcinomas of the esophagus, stomach, and colon exhibit distinct patterns of genome instability and oncogenesis.

Authorship 314539
type: Authorship
author rank in publication: 5
linked author: Shivdasani, Ramesh
linked information resource: Endodermal Hedgehog signals modulate Notch pathway activity in the developing digestive tract mesenchyme.

Authorship 32492
type: Authorship
author rank in publication: 5
linked author: Shivdasani, Ramesh
linked information resource: Cell-type selective chromatin remodeling defines the active subset of FOXA1-bound enhancers.

Authorship 35199
type: Authorship
author rank in publication: 4
linked author: Shivdasani, Ramesh
linked information resource: Hedgehog signaling controls mesenchymal growth in the developing mammalian digestive tract.

Authorship 32942
type: Authorship
author rank in publication: 24
linked author: Shivdasani, Ramesh
linked information resource: The 8q24 cancer risk variant rs6983267 shows long-range interaction with MYC in colorectal cancer.

Authorship 273850
type: Authorship
author rank in publication: 3
linked author: Shivdasani, Ramesh
linked information resource: An upstream, DNase I hypersensitive region of the hematopoietic-expressed transcription factor GATA-1 gene confers developmental specificity in transgenic mice.

Authorship 446851
type: Authorship
author rank in publication: 4
linked author: Shivdasani, Ramesh
linked information resource: Deletion of the GATA domain of TRPS1 causes an absence of facial hair and provides new insights into the bone disorder in inherited tricho-rhino-phalangeal syndromes.

Authorship 570497
type: Authorship
author rank in publication: 5
linked author: Shivdasani, Ramesh
linked information resource: The stomach mesenchymal transcription factor Barx1 specifies gastric epithelial identity through inhibition of transient Wnt signaling.

Authorship 95786
type: Authorship
author rank in publication: 2
linked author: Shivdasani, Ramesh
linked information resource: Genetic evidence that intestinal Notch functions vary regionally and operate through a common mechanism of Math1 repression.

Authorship 282907
type: Authorship
author rank in publication: 8
linked author: Shivdasani, Ramesh
linked information resource: Hic-5 regulates an epithelial program mediated by PPARgamma.

Authorship 310305
type: Authorship
author rank in publication: 9
linked author: Shivdasani, Ramesh
linked information resource: Relationship of CDX2 loss with molecular features and prognosis in colorectal cancer.

Authorship 345403
type: Authorship
author rank in publication: 9
linked author: Shivdasani, Ramesh
linked information resource: Small-molecule antagonists of the oncogenic Tcf/beta-catenin protein complex.

Authorship 349338
type: Authorship
author rank in publication: 4
linked author: Shivdasani, Ramesh
linked information resource: Action of the Caenorhabditis elegans GATA factor END-1 in Xenopus suggests that similar mechanisms initiate endoderm development in ecdysozoa and vertebrates.

Authorship 381558
type: Authorship
author rank in publication: 19
linked author: Shivdasani, Ramesh
linked information resource: Platelets contribute to postnatal occlusion of the ductus arteriosus.

Authorship 384913
type: Authorship
author rank in publication: 5
linked author: Shivdasani, Ramesh
linked information resource: A phase II study of troglitazone, an activator of the PPARgamma receptor, in patients with chemotherapy-resistant metastatic colorectal cancer.

Authorship 223715
type: Authorship
author rank in publication: 4
linked author: Shivdasani, Ramesh
linked information resource: A possible role for the high mobility group box transcription factor Tcf-4 in vertebrate gut epithelial cell differentiation.

Authorship 228884
type: Authorship
author rank in publication: 2
linked author: Shivdasani, Ramesh
linked information resource: Mechanisms of thrombopoiesis.

Authorship 356008
type: Authorship
author rank in publication: 1
linked author: Shivdasani, Ramesh
linked information resource: Lonely in Paris: when one gene copy isn't enough.

Authorship 42069
type: Authorship
author rank in publication: 5
linked author: Shivdasani, Ramesh
linked information resource: Barx1-mediated inhibition of Wnt signaling in the mouse thoracic foregut controls tracheo-esophageal septation and epithelial differentiation.

Authorship 513089
type: Authorship
author rank in publication: 1
linked author: Shivdasani, Ramesh
linked information resource: Molecular regulation of vertebrate early endoderm development.

Authorship 152488
type: Authorship
author rank in publication: 1
linked author: Shivdasani, Ramesh
linked information resource: HLA homozygosity and shared HLA haplotypes in the development of transfusion-associated graft-versus-host disease.

Authorship 273388
type: Authorship
author rank in publication: 4
linked author: Shivdasani, Ramesh
linked information resource: Characterization of adult alpha- and beta-globin genes in the zebrafish.

Authorship 425526
type: Authorship
author rank in publication: 1
linked author: Shivdasani, Ramesh
linked information resource: Culture, expansion, and differentiation of murine megakaryocytes.

Authorship 802272
type: Authorship
author rank in publication: 9
linked author: Shivdasani, Ramesh
linked information resource: The use of murine-derived fundic organoids in studies of gastric physiology.

Authorship 801791
type: Authorship
author rank in publication: 4
linked author: Shivdasani, Ramesh
linked information resource: Transcription factors GATA4 and HNF4A control distinct aspects of intestinal homeostasis in conjunction with transcription factor CDX2.

The use of murine-derived fundic organoids in studies of gastric physiology.
PubMed Identifier: 25605613
author list: Schumacher MA, Aihara E, Feng R, Engevik A, Shroyer NF, Ottemann KM, Worrell RT, Montrose MH, Shivdasani RA, Zavros Y
published in: The Journal of physiology
information resource reference: The use of murine-derived fundic organoids in studies of gastric physiology. J Physiol. 2015 Apr 15; 593(8):1809-27.
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publication date: 2015-02-19T00:00:00
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type: Academic Article
type: Article
type: Document
type: Information Resource

Transcription factors GATA4 and HNF4A control distinct aspects of intestinal homeostasis in conjunction with transcription factor CDX2.
PubMed Identifier: 25488664
author list: San Roman AK, Aronson BE, Krasinski SD, Shivdasani RA, Verzi MP
published in: The Journal of biological chemistry
information resource reference: Transcription factors GATA4 and HNF4A control distinct aspects of intestinal homeostasis in conjunction with transcription factor CDX2. J Biol Chem. 2015 Jan 16; 290(3):1850-60.
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publication date: 2014-12-08T00:00:00
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type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 600929
type: Authorship
linked author: Shivdasani, Ramesh
linked information resource: Transfusion-associated graft-versus-host disease

Authorship 255933
type: Authorship
author rank in publication: 4
linked author: Shivdasani, Ramesh
linked information resource: p45(NFE2) is a negative regulator of erythroid proliferation which contributes to the progression of Friend virus-induced erythroleukemias.

Authorship 256297
type: Authorship
author rank in publication: 6
linked author: Shivdasani, Ramesh
linked information resource: Tricho-rhino-phalangeal syndrome with supernumerary teeth.

Authorship 316011
type: Authorship
author rank in publication: 4
linked author: Shivdasani, Ramesh
linked information resource: Phases of canonical Wnt signaling during the development of mouse intestinal epithelium.

Authorship 501981
type: Authorship
author rank in publication: 1
linked author: Shivdasani, Ramesh
linked information resource: MicroRNAs: regulators of gene expression and cell differentiation.

Authorship 570754
type: Authorship
author rank in publication: 12
linked author: Shivdasani, Ramesh
linked information resource: The Stem Cell Discovery Engine: an integrated repository and analysis system for cancer stem cell comparisons.

Authorship 289285
type: Authorship
author rank in publication: 3
linked author: Shivdasani, Ramesh
linked information resource: Expression and function of Nkx6.3 in vertebrate hindbrain.

Authorship 822280
type: Authorship
author rank in publication: 2
linked author: Shivdasani, Ramesh
linked information resource: Control of stomach smooth muscle development and intestinal rotation by transcription factor BARX1.

Control of stomach smooth muscle development and intestinal rotation by transcription factor BARX1.
PubMed Identifier: 26057579
author list: Jayewickreme CD, Shivdasani RA
published in: Developmental biology
information resource reference: Control of stomach smooth muscle development and intestinal rotation by transcription factor BARX1. Dev Biol. 2015 Sep 01; 405(1):21-32.
journal title abbreviation: Dev Biol
publication date: 2015-06-06T00:00:00
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type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 593704
type: Authorship
linked author: Shivdasani, Ramesh
linked information resource: A Fli in the ointment

Authorship 72530
type: Authorship
author rank in publication: 7
linked author: Shivdasani, Ramesh
linked information resource: Role of the homeodomain transcription factor Bapx1 in mouse distal stomach development.

Authorship 377837
type: Authorship
author rank in publication: 11
linked author: Shivdasani, Ramesh
linked information resource: PU.1 is a major downstream target of AML1 (RUNX1) in adult mouse hematopoiesis.

Authorship 391298
type: Authorship
author rank in publication: 8
linked author: Shivdasani, Ramesh
linked information resource: Characterization of the megakaryocyte demarcation membrane system and its role in thrombopoiesis.

Authorship 843563
type: Authorship
author rank in publication: 10
linked author: Shivdasani, Ramesh
linked information resource: The androgen receptor cistrome is extensively reprogrammed in human prostate tumorigenesis.

The androgen receptor cistrome is extensively reprogrammed in human prostate tumorigenesis.
PubMed Identifier: 26457646
author list: Pomerantz MM, Li F, Takeda DY, Lenci R, Chonkar A, Chabot M, Cejas P, Vazquez F, Cook J, Shivdasani RA, Bowden M, Lis R, Hahn WC, Kantoff PW, Brown M, Loda M, Long HW, Freedman ML
published in: Nature genetics
information resource reference: The androgen receptor cistrome is extensively reprogrammed in human prostate tumorigenesis. Nat Genet. 2015 Nov; 47(11):1346-51.
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publication date: 2015-10-12T00:00:00
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type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 503974
type: Authorship
author rank in publication: 3
linked author: Shivdasani, Ramesh
linked information resource: Expression analysis of primary mouse megakaryocyte differentiation and its application in identifying stage-specific molecular markers and a novel transcriptional target of NF-E2.

Authorship 847861
type: Authorship
author rank in publication: 4
linked author: Shivdasani, Ramesh
linked information resource: Distinct Processes and Transcriptional Targets Underlie CDX2 Requirements in Intestinal Stem Cells and Differentiated Villus Cells.

Distinct Processes and Transcriptional Targets Underlie CDX2 Requirements in Intestinal Stem Cells and Differentiated Villus Cells.
PubMed Identifier: 26489894
author list: San Roman AK, Tovaglieri A, Breault DT, Shivdasani RA
published in: Stem cell reports
information resource reference: Distinct Processes and Transcriptional Targets Underlie CDX2 Requirements in Intestinal Stem Cells and Differentiated Villus Cells. Stem Cell Reports. 2015 Nov 10; 5(5):673-681.
journal title abbreviation: Stem Cell Reports
publication date: 2015-10-17T00:00:00
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type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 470329
type: Authorship
author rank in publication: 1
linked author: Shivdasani, Ramesh
linked information resource: An animal model for myelofibrosis.

Turner, Jerrold
eCommons Login: JRT21
first name: Jerrold
last name: Turner
full name: Jerrold R Turner, M.D., Ph.D.
has faculty rank: Full Professor
Person ID: 145640
person in primary position: Professor of Pathology
type: Agent
type: Person
preferred title: Professor of Pathology

Authorship 864255
type: Authorship
author rank in publication: 18
linked author: Shivdasani, Ramesh
linked information resource: Survival Benefit of Exercise Differs by Tumor IRS1 Expression Status in Colorectal Cancer.

Authorship 865800
type: Authorship
author rank in publication: 2
linked author: Shivdasani, Ramesh
linked information resource: Stomach development, stem cells and disease.

Authorship 869551
type: Authorship
author rank in publication: 11
linked author: Shivdasani, Ramesh
linked information resource: Reprogrammed Stomach Tissue as a Renewable Source of Functional ß Cells for Blood Glucose Regulation.

Survival Benefit of Exercise Differs by Tumor IRS1 Expression Status in Colorectal Cancer.
PubMed Identifier: 26577117
author list: Hanyuda A, Kim SA, Martinez-Fernandez A, Qian ZR, Yamauchi M, Nishihara R, Morikawa T, Liao X, Inamura K, Mima K, Cao Y, Zhang X, Wu K, Chan AT, Giovannucci EL, Meyerhardt JA, Fuchs CS, Shivdasani RA, Ogino S
published in: Annals of surgical oncology
information resource reference: Survival Benefit of Exercise Differs by Tumor IRS1 Expression Status in Colorectal Cancer. Ann Surg Oncol. 2016 Mar; 23(3):908-17.
journal title abbreviation: Ann Surg Oncol
publication date: 2015-11-17T00:00:00
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type: Academic Article
type: Article
type: Document
type: Information Resource

Reprogrammed Stomach Tissue as a Renewable Source of Functional ß Cells for Blood Glucose Regulation.
PubMed Identifier: 26908146
author list: Ariyachet C, Tovaglieri A, Xiang G, Lu J, Shah MS, Richmond CA, Verbeke C, Melton DA, Stanger BZ, Mooney D, Shivdasani RA, Mahony S, Xia Q, Breault DT, Zhou Q
published in: Cell stem cell
information resource reference: Reprogrammed Stomach Tissue as a Renewable Source of Functional ß Cells for Blood Glucose Regulation. Cell Stem Cell. 2016 Mar 03; 18(3):410-21.
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type: Academic Article
type: Article
type: Document
type: Information Resource

Stomach development, stem cells and disease.
PubMed Identifier: 26884394
author list: Kim TH, Shivdasani RA
published in: Development (Cambridge, England)
information resource reference: Stomach development, stem cells and disease. Development. 2016 Feb 15; 143(4):554-65.
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Authorship 32625
type: Authorship
author rank in publication: 1
linked author: Shivdasani, Ramesh
linked information resource: Molecular associations of IA antigens after T-B cell interactions. I. Identification of new molecular associations.

Authorship 376117
type: Authorship
author rank in publication: 3
linked author: Shivdasani, Ramesh
linked information resource: Regulation of megakaryocytopoiesis and platelet production: lessons from animal models.

Authorship 41674
type: Authorship
author rank in publication: 2
linked author: Shivdasani, Ramesh
linked information resource: Notch signaling in stomach epithelial stem cell homeostasis.

Authorship 884831
type: Authorship
author rank in publication: 5
linked author: Shivdasani, Ramesh
linked information resource: Co-culture of Gastric Organoids and Immortalized Stomach Mesenchymal Cells.

Co-culture of Gastric Organoids and Immortalized Stomach Mesenchymal Cells.
PubMed Identifier: 27246019
author list: Bertaux-Skeirik N, Centeno J, Feng R, Schumacher MA, Shivdasani RA, Zavros Y
published in: Methods in molecular biology (Clifton, N.J.)
information resource reference: Co-culture of Gastric Organoids and Immortalized Stomach Mesenchymal Cells. Methods Mol Biol. 2016; 1422:23-31.
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publication date: 2016-01-01T00:00:00
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type: Academic Article
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type: Document
type: Information Resource

Authorship 886370
type: Authorship
author rank in publication: 22
linked author: Shivdasani, Ramesh
linked information resource: Chromatin immunoprecipitation from fixed clinical tissues reveals tumor-specific enhancer profiles.

Authorship 886109
type: Authorship
author rank in publication: 8
linked author: Shivdasani, Ramesh
linked information resource: Acquired Tissue-Specific Promoter Bivalency Is a Basis for PRC2 Necessity in Adult Cells.

Acquired Tissue-Specific Promoter Bivalency Is a Basis for PRC2 Necessity in Adult Cells.
PubMed Identifier: 27212235
author list: Jadhav U, Nalapareddy K, Saxena M, O'Neill NK, Pinello L, Yuan GC, Orkin SH, Shivdasani RA
published in: Cell
information resource reference: Acquired Tissue-Specific Promoter Bivalency Is a Basis for PRC2 Necessity in Adult Cells. Cell. 2016 Jun 02; 165(6):1389-1400.
journal title abbreviation: Cell
publication date: 2016-05-19T00:00:00
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type: Academic Article
type: Article
type: Document
type: Information Resource

Chromatin immunoprecipitation from fixed clinical tissues reveals tumor-specific enhancer profiles.
PubMed Identifier: 27111282
author list: Cejas P, Li L, O'Neill NK, Duarte M, Rao P, Bowden M, Zhou CW, Mendiola M, Burgos E, Feliu J, Moreno-Rubio J, Guadalajara H, Moreno V, García-Olmo D, Bellmunt J, Mullane S, Hirsch M, Sweeney CJ, Richardson A, Liu XS, Brown M, Shivdasani RA, Long HW
published in: Nature medicine
information resource reference: Chromatin immunoprecipitation from fixed clinical tissues reveals tumor-specific enhancer profiles. Nat Med. 2016 06; 22(6):685-91.
journal title abbreviation: Nat Med
publication date: 2016-04-25T00:00:00
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type: Academic Article
type: Article
type: Document
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Authorship 70699
type: Authorship
author rank in publication: 2
linked author: Shivdasani, Ramesh
linked information resource: Molecular mechanisms of megakaryocyte differentiation.

Authorship 79002
type: Authorship
author rank in publication: 1
linked author: Shivdasani, Ramesh
linked information resource: Stem cell transcription factors.

Authorship 588465
type: Authorship
linked author: Shivdasani, Ramesh
linked information resource: Transcription factors in megakaryocyte differentiation and gene expression

Authorship 591399
type: Authorship
linked author: Shivdasani, Ramesh
linked information resource: Molecular mechanisms of megakaryocyte differentiation and platelet production

Assistant Professor
sort order: 2
type: Faculty Rank

Associate Professor
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Fellow or Post Doc
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type: Faculty Rank

Full Professor
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Instructor
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Authorship 623638
type: Authorship
linked author: Shivdasani, Ramesh
linked information resource: Extragonadal germ cell tumors

Authorship 92840
type: Authorship
author rank in publication: 7
linked author: Shivdasani, Ramesh
linked information resource: Requirement of the tissue-restricted homeodomain transcription factor Nkx6.3 in differentiation of gastrin-producing G cells in the stomach antrum.

Authorship 567472
type: Authorship
author rank in publication: 2
linked author: Shivdasani, Ramesh
linked information resource: Toward mechanism-based cancer care.

Authorship 894094
type: Authorship
author rank in publication: 5
linked author: Shivdasani, Ramesh
linked information resource: NF-E2, FLI1 and RUNX1 collaborate at areas of dynamic chromatin to activate transcription in mature mouse megakaryocytes.

NF-E2, FLI1 and RUNX1 collaborate at areas of dynamic chromatin to activate transcription in mature mouse megakaryocytes.
PubMed Identifier: 27457419
author list: Zang C, Luyten A, Chen J, Liu XS, Shivdasani RA
published in: Scientific reports
information resource reference: NF-E2, FLI1 and RUNX1 collaborate at areas of dynamic chromatin to activate transcription in mature mouse megakaryocytes. Sci Rep. 2016 07 26; 6:30255.
journal title abbreviation: Sci Rep
publication date: 2016-07-26T00:00:00
year: 2016
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 495183
type: Authorship
author rank in publication: 6
linked author: Shivdasani, Ramesh
linked information resource: Uncoupling of chondrocyte differentiation and perichondrial mineralization underlies the skeletal dysplasia in tricho-rhino-phalangeal syndrome.

Authorship 586533
type: Authorship
linked author: Shivdasani, Ramesh
linked information resource: Management of extragonadal germ cell tumors

Authorship 68008
type: Authorship
author rank in publication: 9
linked author: Shivdasani, Ramesh
linked information resource: A dynamic expression survey identifies transcription factors relevant in mouse digestive tract development.

Authorship 902612
type: Authorship
author rank in publication: 16
linked author: Shivdasani, Ramesh
linked information resource: Sox2 Suppresses Gastric Tumorigenesis in Mice.

Sox2 Suppresses Gastric Tumorigenesis in Mice.
PubMed Identifier: 27498859
author list: Sarkar A, Huebner AJ, Sulahian R, Anselmo A, Xu X, Flattery K, Desai N, Sebastian C, Yram MA, Arnold K, Rivera M, Mostoslavsky R, Bronson R, Bass AJ, Sadreyev R, Shivdasani RA, Hochedlinger K
published in: Cell reports
information resource reference: Sox2 Suppresses Gastric Tumorigenesis in Mice. Cell Rep. 2016 08 16; 16(7):1929-41.
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type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 91086
type: Authorship
author rank in publication: 1
linked author: Shivdasani, Ramesh
linked information resource: The role of transcription factor NF-E2 in megakaryocyte maturation and platelet production.

Authorship 908684
type: Authorship
author rank in publication: 12
linked author: Shivdasani, Ramesh
linked information resource: Single-Cell Transcript Profiles Reveal Multilineage Priming in Early Progenitors Derived from Lgr5(+) Intestinal Stem Cells.

Single-Cell Transcript Profiles Reveal Multilineage Priming in Early Progenitors Derived from Lgr5(+) Intestinal Stem Cells.
PubMed Identifier: 27524622
author list: Kim TH, Saadatpour A, Guo G, Saxena M, Cavazza A, Desai N, Jadhav U, Jiang L, Rivera MN, Orkin SH, Yuan GC, Shivdasani RA
published in: Cell reports
information resource reference: Single-Cell Transcript Profiles Reveal Multilineage Priming in Early Progenitors Derived from Lgr5(+) Intestinal Stem Cells. Cell Rep. 2016 08 23; 16(8):2053-2060.
journal title abbreviation: Cell Rep
publication date: 2016-08-11T00:00:00
year: 2016
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 55964
type: Authorship
author rank in publication: 25
linked author: Shivdasani, Ramesh
linked information resource: Profiling critical cancer gene mutations in clinical tumor samples.

Cellular and Molecular Regulation of Thrombopoiesis
end date: 2010-06-30
principal investigator name: SHIVDASANI, RAMESH A
start date: 1999-07-01
type: Grant
sponsor award id: R56HL063143

Dana Farber/ Harvard Cancer Center SPORE in Gastrointestinal Cancer
end date: 2025-05-31
principal investigator name: SELLERS, WILLIAM R
start date: 2007-04-01
type: Grant
sponsor award id: P50CA127003

Comprehensive Phenotypic Comparison of Normal and Cancer Stem Cells
end date: 2011-08-31
principal investigator name: SHIVDASANI, RAMESH A
start date: 2009-09-30
type: Grant
sponsor award id: RC2CA148222

Anatomic and functional characterization of the intestinal crypt-villus niche
end date: 2024-08-31
principal investigator name: SHIVDASANI, RAMESH A
start date: 2014-09-01
type: Grant
sponsor award id: U01DK103152

Gene expression in the mammalian intestine
end date: 2008-01-31
principal investigator name: SHIVDASANI, RAMESH A
start date: 2002-02-01
type: Grant
sponsor award id: R01DK061139

NF E2 AND GLOBIN GENE EXPRESSION AND HEMATOPOIESIS
end date: 1998-04-30
principal investigator name: SHIVDASANI, RAMESH A
start date: 1995-05-01
type: Grant
sponsor award id: K08HL003290

Transcriptional control of gut epithelial homeostasis and regeneration
end date: 2024-03-31
principal investigator name: SHIVDASANI, RAMESH A
start date: 2008-04-01
type: Grant
sponsor award id: R01DK081113

Transcriptional control and enhancer recruitment in mouse and human intestinal secretory differentiation
end date: 2028-02-29
principal investigator name: SHIVDASANI, RAMESH A
start date: 2010-09-01
type: Grant
sponsor award id: R01DK082889

Cellular and Molecular Regulation of Thrombopoiesis
end date: 2014-04-30
principal investigator name: SHIVDASANI, RAMESH A
start date: 1999-07-01
type: Grant
sponsor award id: R01HL063143

Principal Investigator
type: Researcher Role
researcher role of: Shivdasani, Ramesh
contributes to: NF E2 AND GLOBIN GENE EXPRESSION AND HEMATOPOIESIS

Principal Investigator
type: Researcher Role
researcher role of: Shivdasani, Ramesh
contributes to: Anatomic and functional characterization of the intestinal crypt-villus niche

Co-Principal Investigator
type: Researcher Role
researcher role of: Shivdasani, Ramesh
contributes to: Dana Farber/ Harvard Cancer Center SPORE in Gastrointestinal Cancer

Principal Investigator
type: Researcher Role
researcher role of: Shivdasani, Ramesh
contributes to: Cellular and Molecular Regulation of Thrombopoiesis

Co-Principal Investigator
type: Researcher Role
researcher role of: Shivdasani, Ramesh
contributes to: Comprehensive Phenotypic Comparison of Normal and Cancer Stem Cells

Principal Investigator
type: Researcher Role
researcher role of: Shivdasani, Ramesh
contributes to: Transcriptional control and enhancer recruitment in mouse and human intestinal secretory differentiation

Principal Investigator
type: Researcher Role
researcher role of: Shivdasani, Ramesh
contributes to: Gene expression in the mammalian intestine

Principal Investigator
type: Researcher Role
researcher role of: Shivdasani, Ramesh
contributes to: Transcriptional control of gut epithelial homeostasis and regeneration

Principal Investigator
type: Researcher Role
researcher role of: Shivdasani, Ramesh
contributes to: Cellular and Molecular Regulation of Thrombopoiesis

Authorship 99332
type: Authorship
author rank in publication: 2
linked author: Shivdasani, Ramesh
linked information resource: Mechanisms of organelle transport and capture along proplatelets during platelet production.

Authorship 596025
type: Authorship
linked author: Shivdasani, Ramesh
linked information resource: Regulation of megakaryocyte and erythroid differentiation by NF-E2

Authorship 341905
type: Authorship
author rank in publication: 1
linked author: Shivdasani, Ramesh
linked information resource: Molecular and transcriptional regulation of megakaryocyte differentiation.

Authorship 470819
type: Authorship
author rank in publication: 2
linked author: Shivdasani, Ramesh
linked information resource: Megakaryocytes and beyond: the birth of platelets.

Authorship 481504
type: Authorship
author rank in publication: 2
linked author: Shivdasani, Ramesh
linked information resource: Regulation of gene expression with double-stranded phosphorothioate oligonucleotides.

Authorship 934158
type: Authorship
author rank in publication: 10
linked author: Shivdasani, Ramesh
linked information resource: SOX15 governs transcription in human stratified epithelia and a subset of esophageal adenocarcinomas.

SOX15 governs transcription in human stratified epithelia and a subset of esophageal adenocarcinomas.
PubMed Identifier: 26516633
author list: Sulahian R, Chen J, Arany Z, Jadhav U, Peng S, Rustgi AK, Bass AJ, Srivastava A, Hornick JL, Shivdasani RA
published in: Cellular and molecular gastroenterology and hepatology
information resource reference: SOX15 governs transcription in human stratified epithelia and a subset of esophageal adenocarcinomas. Cell Mol Gastroenterol Hepatol. 2015 Nov 01; 1(6):598-609.e6.
journal title abbreviation: Cell Mol Gastroenterol Hepatol
publication date: 2015-11-01T00:00:00
year: 2015
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 940092
type: Authorship
author rank in publication: 12
linked author: Shivdasani, Ramesh
linked information resource: Transcriptional Regulator CNOT3 Defines an Aggressive Colorectal Cancer Subtype.

Transcriptional Regulator CNOT3 Defines an Aggressive Colorectal Cancer Subtype.
PubMed Identifier: 27899379
author list: Cejas P, Cavazza A, Yandava CN, Moreno V, Horst D, Moreno-Rubio J, Burgos E, Mendiola M, Taing L, Goel A, Feliu J, Shivdasani RA
published in: Cancer research
information resource reference: Transcriptional Regulator CNOT3 Defines an Aggressive Colorectal Cancer Subtype. Cancer Res. 2017 02 01; 77(3):766-779.
journal title abbreviation: Cancer Res
publication date: 2016-11-29T00:00:00
year: 2016
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 386092
type: Authorship
author rank in publication: 1
linked author: Shivdasani, Ramesh
linked information resource: A lineage-selective knockout establishes the critical role of transcription factor GATA-1 in megakaryocyte growth and platelet development.

Authorship 941190
type: Authorship
author rank in publication: 8
linked author: Shivdasani, Ramesh
linked information resource: ARID1A loss impairs enhancer-mediated gene regulation and drives colon cancer in mice.

ARID1A loss impairs enhancer-mediated gene regulation and drives colon cancer in mice.
PubMed Identifier: 27941798
author list: Mathur R, Alver BH, San Roman AK, Wilson BG, Wang X, Agoston AT, Park PJ, Shivdasani RA, Roberts CW
published in: Nature genetics
information resource reference: ARID1A loss impairs enhancer-mediated gene regulation and drives colon cancer in mice. Nat Genet. 2017 Feb; 49(2):296-302.
journal title abbreviation: Nat Genet
publication date: 2016-12-12T00:00:00
year: 2016
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 397960
type: Authorship
author rank in publication: 4
linked author: Shivdasani, Ramesh
linked information resource: Regulation of mouse stomach development and Barx1 expression by specific microRNAs.

Authorship 421095
type: Authorship
author rank in publication: 4
linked author: Shivdasani, Ramesh
linked information resource: Transcription factor foxq1 controls mucin gene expression and granule content in mouse stomach surface mucous cells.

Authorship 486873
type: Authorship
author rank in publication: 7
linked author: Shivdasani, Ramesh
linked information resource: High-resolution analysis of genetic alterations in small bowel carcinoid tumors reveals areas of recurrent amplification and loss.

Authorship 957055
type: Authorship
author rank in publication: 2
linked author: Shivdasani, Ramesh
linked information resource: Natural Selection, Crypt Fitness, and Pol III Dependency in the Intestine.

Natural Selection, Crypt Fitness, and Pol III Dependency in the Intestine.
PubMed Identifier: 28174745
author list: Jadhav U, Shivdasani RA
published in: Cellular and molecular gastroenterology and hepatology
information resource reference: Natural Selection, Crypt Fitness, and Pol III Dependency in the Intestine. Cell Mol Gastroenterol Hepatol. 2016 Nov; 2(6):714-715.
journal title abbreviation: Cell Mol Gastroenterol Hepatol
publication date: 2016-09-26T00:00:00
year: 2016
type: Academic Article
type: Article
type: Document
type: Information Resource

Megakaryocyte-osteoblast interaction revealed in mice deficient in transcription factors GATA-1 and NF-E2.
PubMed Identifier: 15005853
author list: Kacena MA, Shivdasani RA, Wilson K, Xi Y, Troiano N, Nazarian A, Gundberg CM, Bouxsein ML, Lorenzo JA, Horowitz MC
published in: Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research
information resource reference: Megakaryocyte-osteoblast interaction revealed in mice deficient in transcription factors GATA-1 and NF-E2. J Bone Miner Res. 2004 Apr; 19(4):652-60.
journal title abbreviation: J Bone Miner Res
publication date: 2003-12-22T00:00:00
year: 2003
type: Academic Article
type: Article
type: Document
type: Information Resource

Characterization of the megakaryocyte demarcation membrane system and its role in thrombopoiesis.
PubMed Identifier: 16434494
author list: Schulze H, Korpal M, Hurov J, Kim SW, Zhang J, Cantley LC, Graf T, Shivdasani RA
published in: Blood
information resource reference: Characterization of the megakaryocyte demarcation membrane system and its role in thrombopoiesis. Blood. 2006 May 15; 107(10):3868-75.
journal title abbreviation: Blood
publication date: 2006-01-24T00:00:00
year: 2006
type: Academic Article
type: Article
type: Document
type: Information Resource

Downregulation of Hedgehog signaling is required for organogenesis of the small intestine in Xenopus.
PubMed Identifier: 11133163
author list: Zhang J, Rosenthal A, de Sauvage FJ, Shivdasani RA
published in: Developmental biology
information resource reference: Downregulation of Hedgehog signaling is required for organogenesis of the small intestine in Xenopus. Dev Biol. 2001 Jan 01; 229(1):188-202.
journal title abbreviation: Dev Biol
publication date: 2001-01-01T00:00:00
year: 2001
type: Academic Article
type: Article
type: Document
type: Information Resource

Transcriptional repression and developmental functions of the atypical vertebrate GATA protein TRPS1.
PubMed Identifier: 11285235
author list: Malik TH, Shoichet SA, Latham P, Kroll TG, Peters LL, Shivdasani RA
published in: The EMBO journal
information resource reference: Transcriptional repression and developmental functions of the atypical vertebrate GATA protein TRPS1. EMBO J. 2001 Apr 02; 20(7):1715-25.
journal title abbreviation: EMBO J
publication date: 2001-04-02T00:00:00
year: 2001
type: Academic Article
type: Article
type: Document
type: Information Resource

Characterization of a novel mammalian Groucho isoform and its role in transcriptional regulation.
PubMed Identifier: 12359720
author list: Lepourcelet M, Shivdasani RA
published in: The Journal of biological chemistry
information resource reference: Characterization of a novel mammalian Groucho isoform and its role in transcriptional regulation. J Biol Chem. 2002 Dec 06; 277(49):47732-40.
journal title abbreviation: J Biol Chem
publication date: 2002-09-30T00:00:00
year: 2002
type: Academic Article
type: Article
type: Document
type: Information Resource

Expression and function of Nkx6.3 in vertebrate hindbrain.
PubMed Identifier: 18586225
author list: Hafler BP, Choi MY, Shivdasani RA, Rowitch DH
published in: Brain research
information resource reference: Expression and function of Nkx6.3 in vertebrate hindbrain. Brain Res. 2008 Jul 30; 1222:42-50.
journal title abbreviation: Brain Res
publication date: 2008-05-06T00:00:00
year: 2008
type: Academic Article
type: Article
type: Document
type: Information Resource

Singh, Pratik
eCommons Login: PNS6
first name: Pratik
last name: Singh
full name: Pratik Narendra Pratap Singh, Ph.D.
has faculty rank: Fellow or Post Doc
Person ID: 157517
person in primary position: Research Fellow in Medicine
type: Agent
type: Person
preferred title: Research Fellow in Medicine

Anion exchanger 1 (band 3) is required to prevent erythrocyte membrane surface loss but not to form the membrane skeleton.
PubMed Identifier: 8808627
author list: Peters LL, Shivdasani RA, Liu SC, Hanspal M, John KM, Gonzalez JM, Brugnara C, Gwynn B, Mohandas N, Alper SL, Orkin SH, Lux SE
published in: Cell
information resource reference: Anion exchanger 1 (band 3) is required to prevent erythrocyte membrane surface loss but not to form the membrane skeleton. Cell. 1996 Sep 20; 86(6):917-27.
journal title abbreviation: Cell
publication date: 1996-09-20T00:00:00
year: 1996
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 979005
type: Authorship
author rank in publication: 9
linked author: Shivdasani, Ramesh
linked information resource: Somatic copy number alterations in gastric adenocarcinomas among Asian and Western patients.

Somatic copy number alterations in gastric adenocarcinomas among Asian and Western patients.
PubMed Identifier: 28426752
author list: Schumacher SE, Shim BY, Corso G, Ryu MH, Kang YK, Roviello F, Saksena G, Peng S, Shivdasani RA, Bass AJ, Beroukhim R
published in: PloS one
information resource reference: Somatic copy number alterations in gastric adenocarcinomas among Asian and Western patients. PLoS One. 2017; 12(4):e0176045.
journal title abbreviation: PLoS One
publication date: 2017-04-20T00:00:00
year: 2017
type: Academic Article
type: Article
type: Document
type: Information Resource

Deletion of the GATA domain of TRPS1 causes an absence of facial hair and provides new insights into the bone disorder in inherited tricho-rhino-phalangeal syndromes.
PubMed Identifier: 12446778
author list: Malik TH, Von Stechow D, Bronson RT, Shivdasani RA
published in: Molecular and cellular biology
information resource reference: Deletion of the GATA domain of TRPS1 causes an absence of facial hair and provides new insights into the bone disorder in inherited tricho-rhino-phalangeal syndromes. Mol Cell Biol. 2002 Dec; 22(24):8592-600.
journal title abbreviation: Mol Cell Biol
publication date: 2002-12-01T00:00:00
year: 2002
type: Academic Article
type: Article
type: Document
type: Information Resource

Regulation of megakaryocytopoiesis and platelet production: lessons from animal models.
PubMed Identifier: 9626984
author list: de Sauvage FJ, Villeval JL, Shivdasani RA
published in: The Journal of laboratory and clinical medicine
information resource reference: Regulation of megakaryocytopoiesis and platelet production: lessons from animal models. J Lab Clin Med. 1998 Jun; 131(6):496-501.
journal title abbreviation: J Lab Clin Med
publication date: 1998-06-01T00:00:00
year: 1998
type: Academic Article
type: Article
type: Document
type: Information Resource

The role of transcription factor NF-E2 in megakaryocyte maturation and platelet production.
PubMed Identifier: 11012210
author list: Shivdasani RA
published in: Stem cells (Dayton, Ohio)
information resource reference: The role of transcription factor NF-E2 in megakaryocyte maturation and platelet production. Stem Cells. 1996; 14 Suppl 1:112-5.
journal title abbreviation: Stem Cells
publication date: 1996-01-01T00:00:00
year: 1996
type: Academic Article
type: Article
type: Document
type: Information Resource

Science, another culture: an essay after C. P. Snow.
PubMed Identifier: 2813501
author list: Shivdasani RA
published in: The Pharos of Alpha Omega Alpha-Honor Medical Society. Alpha Omega Alpha
information resource reference: Science, another culture: an essay after C. P. Snow. Pharos Alpha Omega Alpha Honor Med Soc. 1989; 52(4):21-4.
journal title abbreviation: Pharos Alpha Omega Alpha Honor Med Soc
publication date: 1989-01-01T00:00:00
year: 1989
type: Academic Article
type: Article
type: Document
type: Information Resource

Mice lacking transcription factor NF-E2 provide in vivo validation of the proplatelet model of thrombocytopoiesis and show a platelet production defect that is intrinsic to megakaryocytes.
PubMed Identifier: 9716588
author list: Lecine P, Villeval JL, Vyas P, Swencki B, Xu Y, Shivdasani RA
published in: Blood
information resource reference: Mice lacking transcription factor NF-E2 provide in vivo validation of the proplatelet model of thrombocytopoiesis and show a platelet production defect that is intrinsic to megakaryocytes. Blood. 1998 Sep 01; 92(5):1608-16.
journal title abbreviation: Blood
publication date: 1998-09-01T00:00:00
year: 1998
type: Academic Article
type: Article
type: Document
type: Information Resource

Molecular regulation of vertebrate early endoderm development.
PubMed Identifier: 12221001
author list: Shivdasani RA
published in: Developmental biology
information resource reference: Molecular regulation of vertebrate early endoderm development. Dev Biol. 2002 Sep 15; 249(2):191-203.
journal title abbreviation: Dev Biol
publication date: 2002-09-15T00:00:00
year: 2002
type: Academic Article
type: Article
type: Document
type: Information Resource

A phase II study of troglitazone, an activator of the PPARgamma receptor, in patients with chemotherapy-resistant metastatic colorectal cancer.
PubMed Identifier: 12416897
author list: Kulke MH, Demetri GD, Sharpless NE, Ryan DP, Shivdasani R, Clark JS, Spiegelman BM, Kim H, Mayer RJ, Fuchs CS
published in: Cancer journal (Sudbury, Mass.)
information resource reference: A phase II study of troglitazone, an activator of the PPARgamma receptor, in patients with chemotherapy-resistant metastatic colorectal cancer. Cancer J. 2002 Sep-Oct; 8(5):395-9.
journal title abbreviation: Cancer J
publication date: 2002-09-01T00:00:00
year: 2002
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 983217
type: Authorship
author rank in publication: 14
linked author: Shivdasani, Ramesh
linked information resource: Challenges and emerging directions in single-cell analysis.

Challenges and emerging directions in single-cell analysis.
PubMed Identifier: 28482897
author list: Yuan GC, Cai L, Elowitz M, Enver T, Fan G, Guo G, Irizarry R, Kharchenko P, Kim J, Orkin S, Quackenbush J, Saadatpour A, Schroeder T, Shivdasani R, Tirosh I
published in: Genome biology
information resource reference: Challenges and emerging directions in single-cell analysis. Genome Biol. 2017 05 08; 18(1):84.
journal title abbreviation: Genome Biol
publication date: 2017-05-08T00:00:00
year: 2017
type: Academic Article
type: Article
type: Document
type: Information Resource

A "knockdown" mutation created by cis-element gene targeting reveals the dependence of erythroid cell maturation on the level of transcription factor GATA-1.
PubMed Identifier: 9192642
author list: McDevitt MA, Shivdasani RA, Fujiwara Y, Yang H, Orkin SH
published in: Proceedings of the National Academy of Sciences of the United States of America
information resource reference: A "knockdown" mutation created by cis-element gene targeting reveals the dependence of erythroid cell maturation on the level of transcription factor GATA-1. Proc Natl Acad Sci U S A. 1997 Jun 24; 94(13):6781-5.
journal title abbreviation: Proc Natl Acad Sci U S A
publication date: 1997-06-24T00:00:00
year: 1997
type: Academic Article
type: Article
type: Document
type: Information Resource

A possible role for the high mobility group box transcription factor Tcf-4 in vertebrate gut epithelial cell differentiation.
PubMed Identifier: 9880534
author list: Lee YJ, Swencki B, Shoichet S, Shivdasani RA
published in: The Journal of biological chemistry
information resource reference: A possible role for the high mobility group box transcription factor Tcf-4 in vertebrate gut epithelial cell differentiation. J Biol Chem. 1999 Jan 15; 274(3):1566-72.
journal title abbreviation: J Biol Chem
publication date: 1999-01-15T00:00:00
year: 1999
type: Academic Article
type: Article
type: Document
type: Information Resource

Overlapping gene expression in fetal mouse intestine development and human colorectal cancer.
PubMed Identifier: 16204040
author list: Hu M, Shivdasani RA
published in: Cancer research
information resource reference: Overlapping gene expression in fetal mouse intestine development and human colorectal cancer. Cancer Res. 2005 Oct 01; 65(19):8715-22.
journal title abbreviation: Cancer Res
publication date: 2005-10-01T00:00:00
year: 2005
type: Academic Article
type: Article
type: Document
type: Information Resource

Endodermal Hedgehog signals modulate Notch pathway activity in the developing digestive tract mesenchyme.
PubMed Identifier: 21750033
author list: Kim TH, Kim BM, Mao J, Rowan S, Shivdasani RA
published in: Development (Cambridge, England)
information resource reference: Endodermal Hedgehog signals modulate Notch pathway activity in the developing digestive tract mesenchyme. Development. 2011 Aug; 138(15):3225-33.
journal title abbreviation: Development
publication date: 2011-08-01T00:00:00
year: 2011
type: Academic Article
type: Article
type: Document
type: Information Resource

Differential roles of microtubule assembly and sliding in proplatelet formation by megakaryocytes.
PubMed Identifier: 16118321
author list: Patel SR, Richardson JL, Schulze H, Kahle E, Galjart N, Drabek K, Shivdasani RA, Hartwig JH, Italiano JE
published in: Blood
information resource reference: Differential roles of microtubule assembly and sliding in proplatelet formation by megakaryocytes. Blood. 2005 Dec 15; 106(13):4076-85.
journal title abbreviation: Blood
publication date: 2005-08-23T00:00:00
year: 2005
type: Academic Article
type: Article
type: Document
type: Information Resource

An upstream, DNase I hypersensitive region of the hematopoietic-expressed transcription factor GATA-1 gene confers developmental specificity in transgenic mice.
PubMed Identifier: 9223298
author list: McDevitt MA, Fujiwara Y, Shivdasani RA, Orkin SH
published in: Proceedings of the National Academy of Sciences of the United States of America
information resource reference: An upstream, DNase I hypersensitive region of the hematopoietic-expressed transcription factor GATA-1 gene confers developmental specificity in transgenic mice. Proc Natl Acad Sci U S A. 1997 Jul 22; 94(15):7976-81.
journal title abbreviation: Proc Natl Acad Sci U S A
publication date: 1997-07-22T00:00:00
year: 1997
type: Academic Article
type: Article
type: Document
type: Information Resource

Loss of the PlagL2 transcription factor affects lacteal uptake of chylomicrons.
PubMed Identifier: 17983586
author list: Van Dyck F, Braem CV, Chen Z, Declercq J, Deckers R, Kim BM, Ito S, Wu MK, Cohen DE, Dewerchin M, Derua R, Waelkens E, Fiette L, Roebroek A, Schuit F, Van de Ven WJ, Shivdasani RA
published in: Cell metabolism
information resource reference: Loss of the PlagL2 transcription factor affects lacteal uptake of chylomicrons. Cell Metab. 2007 Nov; 6(5):406-13.
journal title abbreviation: Cell Metab
publication date: 2007-11-01T00:00:00
year: 2007
type: Academic Article
type: Article
type: Document
type: Information Resource

PU.1 is a major downstream target of AML1 (RUNX1) in adult mouse hematopoiesis.
PubMed Identifier: 17994017
author list: Huang G, Zhang P, Hirai H, Elf S, Yan X, Chen Z, Koschmieder S, Okuno Y, Dayaram T, Growney JD, Shivdasani RA, Gilliland DG, Speck NA, Nimer SD, Tenen DG
published in: Nature genetics
information resource reference: PU.1 is a major downstream target of AML1 (RUNX1) in adult mouse hematopoiesis. Nat Genet. 2008 Jan; 40(1):51-60.
journal title abbreviation: Nat Genet
publication date: 2007-11-11T00:00:00
year: 2007
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 987666
type: Authorship
author rank in publication: 19
linked author: Shivdasani, Ramesh
linked information resource: https://connects.catalyst.harvard.edu/Profiles/profile/82898925

https://connects.catalyst.harvard.edu/Profiles/profile/82898925
PubMed Identifier: 28583825
author list: Spechler SJ, Merchant JL, Wang TC, Chandrasoma P, Fox JG, Genta RM, Goldenring JR, Hayakawa Y, Kuipers EJ, Lund PK, McKeon F, Mills JC, Odze RD, Peek RM, Pham T, Que J, Rustgi AK, Shaheen NJ, Shivdasani RA, Souza RF, Storz P, Todisco A, Wang DH, Wright NA
published in: Gastroenterology
information resource reference: A Summary of the 2016 James W. Freston Conference of the American Gastroenterological Association: Intestinal Metaplasia in the Esophagus and Stomach: Origins, Differences, Similarities and Significance. Gastroenterology. 2017 Jul; 153(1):e6-e13.
journal title abbreviation: Gastroenterology
publication date: 2017-06-03T00:00:00
year: 2017
type: Academic Article
type: Article
type: Document
type: Information Resource
label: A Summary of the 2016 James W. Freston Conference of the American Gastroenterological Association: Intestinal Metaplasia in the Esophagus and Stomach: Origins, Differences, Similarities and Significance.

Molecular mechanisms of megakaryocyte differentiation.
PubMed Identifier: 15354260
author list: Schulze H, Shivdasani RA
published in: Seminars in thrombosis and hemostasis
information resource reference: Molecular mechanisms of megakaryocyte differentiation. Semin Thromb Hemost. 2004 Aug; 30(4):389-98.
journal title abbreviation: Semin Thromb Hemost
publication date: 2004-08-01T00:00:00
year: 2004
type: Academic Article
type: Article
type: Document
type: Information Resource

Visualization of microtubule growth in living platelets reveals a dynamic marginal band with multiple microtubules.
PubMed Identifier: 18230754
author list: Patel-Hett S, Richardson JL, Schulze H, Drabek K, Isaac NA, Hoffmeister K, Shivdasani RA, Bulinski JC, Galjart N, Hartwig JH, Italiano JE
published in: Blood
information resource reference: Visualization of microtubule growth in living platelets reveals a dynamic marginal band with multiple microtubules. Blood. 2008 May 01; 111(9):4605-16.
journal title abbreviation: Blood
publication date: 2008-01-29T00:00:00
year: 2008
type: Academic Article
type: Article
type: Document
type: Information Resource

Consequences of GATA-1 deficiency in megakaryocytes and platelets.
PubMed Identifier: 10216081
author list: Vyas P, Ault K, Jackson CW, Orkin SH, Shivdasani RA
published in: Blood
information resource reference: Consequences of GATA-1 deficiency in megakaryocytes and platelets. Blood. 1999 May 01; 93(9):2867-75.
journal title abbreviation: Blood
publication date: 1999-05-01T00:00:00
year: 1999
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 992810
type: Authorship
author rank in publication: 8
linked author: Shivdasani, Ramesh
linked information resource: Dynamic Reorganization of Chromatin Accessibility Signatures during Dedifferentiation of Secretory Precursors into Lgr5+ Intestinal Stem Cells.

Dynamic Reorganization of Chromatin Accessibility Signatures during Dedifferentiation of Secretory Precursors into Lgr5+ Intestinal Stem Cells.
PubMed Identifier: 28648363
author list: Jadhav U, Saxena M, O'Neill NK, Saadatpour A, Yuan GC, Herbert Z, Murata K, Shivdasani RA
published in: Cell stem cell
information resource reference: Dynamic Reorganization of Chromatin Accessibility Signatures during Dedifferentiation of Secretory Precursors into Lgr5+ Intestinal Stem Cells. Cell Stem Cell. 2017 07 06; 21(1):65-77.e5.
journal title abbreviation: Cell Stem Cell
publication date: 2017-06-22T00:00:00
year: 2017
type: Academic Article
type: Article
type: Document
type: Information Resource

Genetic evidence that intestinal Notch functions vary regionally and operate through a common mechanism of Math1 repression.
PubMed Identifier: 21282114
author list: Kim TH, Shivdasani RA
published in: The Journal of biological chemistry
information resource reference: Genetic evidence that intestinal Notch functions vary regionally and operate through a common mechanism of Math1 repression. J Biol Chem. 2011 Apr 01; 286(13):11427-33.
journal title abbreviation: J Biol Chem
publication date: 2011-01-31T00:00:00
year: 2011
type: Academic Article
type: Article
type: Document
type: Information Resource

Interactions between the megakaryocyte/platelet-specific beta1 tubulin and the secretory leukocyte protease inhibitor SLPI suggest a role for regulated proteolysis in platelet functions.
PubMed Identifier: 15315966
author list: Schulze H, Korpal M, Bergmeier W, Italiano JE, Wahl SM, Shivdasani RA
published in: Blood
information resource reference: Interactions between the megakaryocyte/platelet-specific beta1 tubulin and the secretory leukocyte protease inhibitor SLPI suggest a role for regulated proteolysis in platelet functions. Blood. 2004 Dec 15; 104(13):3949-57.
journal title abbreviation: Blood
publication date: 2004-08-17T00:00:00
year: 2004
type: Academic Article
type: Article
type: Document
type: Information Resource

Hic-5 regulates an epithelial program mediated by PPARgamma.
PubMed Identifier: 15687259
author list: Drori S, Girnun GD, Tou L, Szwaya JD, Mueller E, Xia K, Kia X, Shivdasani RA, Spiegelman BM
published in: Genes & development
information resource reference: Hic-5 regulates an epithelial program mediated by PPARgamma. Genes Dev. 2005 Feb 01; 19(3):362-75.
journal title abbreviation: Genes Dev
publication date: 2005-02-01T00:00:00
year: 2005
type: Academic Article
type: Article
type: Document
type: Information Resource

Two roles for Ia in antigen-specific T lymphocyte activation.
PubMed Identifier: 3491135
author list: Kim KH, Shivdasani RA, Thomas DW
published in: Journal of immunology (Baltimore, Md. : 1950)
information resource reference: Two roles for Ia in antigen-specific T lymphocyte activation. J Immunol. 1986 Dec 01; 137(11):3393-400.
journal title abbreviation: J Immunol
publication date: 1986-12-01T00:00:00
year: 1986
type: Academic Article
type: Article
type: Document
type: Information Resource

Transcription factor NF-E2 is required for platelet formation independent of the actions of thrombopoietin/MGDF in megakaryocyte development.
PubMed Identifier: 7774011
author list: Shivdasani RA, Rosenblatt MF, Zucker-Franklin D, Jackson CW, Hunt P, Saris CJ, Orkin SH
published in: Cell
information resource reference: Transcription factor NF-E2 is required for platelet formation independent of the actions of thrombopoietin/MGDF in megakaryocyte development. Cell. 1995 Jun 02; 81(5):695-704.
journal title abbreviation: Cell
publication date: 1995-06-02T00:00:00
year: 1995
type: Academic Article
type: Article
type: Document
type: Information Resource

Insights into developmental mechanisms and cancers in the mammalian intestine derived from serial analysis of gene expression and study of the hepatoma-derived growth factor (HDGF).
PubMed Identifier: 15604097
author list: Lepourcelet M, Tou L, Cai L, Sawada J, Lazar AJ, Glickman JN, Williamson JA, Everett AD, Redston M, Fox EA, Nakatani Y, Shivdasani RA
published in: Development (Cambridge, England)
information resource reference: Insights into developmental mechanisms and cancers in the mammalian intestine derived from serial analysis of gene expression and study of the hepatoma-derived growth factor (HDGF). Development. 2005 Jan; 132(2):415-27.
journal title abbreviation: Development
publication date: 2004-12-16T00:00:00
year: 2004
type: Academic Article
type: Article
type: Document
type: Information Resource

A dynamic expression survey identifies transcription factors relevant in mouse digestive tract development.
PubMed Identifier: 16971476
author list: Choi MY, Romer AI, Hu M, Lepourcelet M, Mechoor A, Yesilaltay A, Krieger M, Gray PA, Shivdasani RA
published in: Development (Cambridge, England)
information resource reference: A dynamic expression survey identifies transcription factors relevant in mouse digestive tract development. Development. 2006 Oct; 133(20):4119-29.
journal title abbreviation: Development
publication date: 2006-09-13T00:00:00
year: 2006
type: Academic Article
type: Article
type: Document
type: Information Resource

Intestinal master transcription factor CDX2 controls chromatin access for partner transcription factor binding.
PubMed Identifier: 23129810
author list: Verzi MP, Shin H, San Roman AK, Liu XS, Shivdasani RA
published in: Molecular and cellular biology
information resource reference: Intestinal master transcription factor CDX2 controls chromatin access for partner transcription factor binding. Mol Cell Biol. 2013 Jan; 33(2):281-92.
journal title abbreviation: Mol Cell Biol
publication date: 2012-11-05T00:00:00
year: 2012
type: Academic Article
type: Article
type: Document
type: Information Resource

Differentiation-specific histone modifications reveal dynamic chromatin interactions and partners for the intestinal transcription factor CDX2.
PubMed Identifier: 21074721
author list: Verzi MP, Shin H, He HH, Sulahian R, Meyer CA, Montgomery RK, Fleet JC, Brown M, Liu XS, Shivdasani RA
published in: Developmental cell
information resource reference: Differentiation-specific histone modifications reveal dynamic chromatin interactions and partners for the intestinal transcription factor CDX2. Dev Cell. 2010 Nov 16; 19(5):713-26.
journal title abbreviation: Dev Cell
publication date: 2010-11-16T00:00:00
year: 2010
type: Academic Article
type: Article
type: Document
type: Information Resource

Molecular and transcriptional regulation of megakaryocyte differentiation.
PubMed Identifier: 11553848
author list: Shivdasani RA
published in: Stem cells (Dayton, Ohio)
information resource reference: Molecular and transcriptional regulation of megakaryocyte differentiation. Stem Cells. 2001; 19(5):397-407.
journal title abbreviation: Stem Cells
publication date: 2001-01-01T00:00:00
year: 2001
type: Academic Article
type: Article
type: Document
type: Information Resource

Mechanisms and implications of platelet discoid shape.
PubMed Identifier: 12586623
author list: Italiano JE, Bergmeier W, Tiwari S, Falet H, Hartwig JH, Hoffmeister KM, André P, Wagner DD, Shivdasani RA
published in: Blood
information resource reference: Mechanisms and implications of platelet discoid shape. Blood. 2003 Jun 15; 101(12):4789-96.
journal title abbreviation: Blood
publication date: 2003-02-13T00:00:00
year: 2003
type: Academic Article
type: Article
type: Document
type: Information Resource

Transcription factor foxq1 controls mucin gene expression and granule content in mouse stomach surface mucous cells.
PubMed Identifier: 18558092
author list: Verzi MP, Khan AH, Ito S, Shivdasani RA
published in: Gastroenterology
information resource reference: Transcription factor foxq1 controls mucin gene expression and granule content in mouse stomach surface mucous cells. Gastroenterology. 2008 Aug; 135(2):591-600.
journal title abbreviation: Gastroenterology
publication date: 2008-04-22T00:00:00
year: 2008
type: Academic Article
type: Article
type: Document
type: Information Resource

CDK8 is a colorectal cancer oncogene that regulates beta-catenin activity.
PubMed Identifier: 18794900
author list: Firestein R, Bass AJ, Kim SY, Dunn IF, Silver SJ, Guney I, Freed E, Ligon AH, Vena N, Ogino S, Chheda MG, Tamayo P, Finn S, Shrestha Y, Boehm JS, Jain S, Bojarski E, Mermel C, Barretina J, Chan JA, Baselga J, Tabernero J, Root DE, Fuchs CS, Loda M, Shivdasani RA, Meyerson M, Hahn WC
published in: Nature
information resource reference: CDK8 is a colorectal cancer oncogene that regulates beta-catenin activity. Nature. 2008 Sep 25; 455(7212):547-51.
journal title abbreviation: Nature
publication date: 2008-09-14T00:00:00
year: 2008
type: Academic Article
type: Article
type: Document
type: Information Resource

Relationship of CDX2 loss with molecular features and prognosis in colorectal cancer.
PubMed Identifier: 19584150
author list: Baba Y, Nosho K, Shima K, Freed E, Irahara N, Philips J, Meyerhardt JA, Hornick JL, Shivdasani RA, Fuchs CS, Ogino S
published in: Clinical cancer research : an official journal of the American Association for Cancer Research
information resource reference: Relationship of CDX2 loss with molecular features and prognosis in colorectal cancer. Clin Cancer Res. 2009 Jul 15; 15(14):4665-73.
journal title abbreviation: Clin Cancer Res
publication date: 2009-07-07T00:00:00
year: 2009
type: Academic Article
type: Article
type: Document
type: Information Resource

Characterization of adult alpha- and beta-globin genes in the zebrafish.
PubMed Identifier: 9002973
author list: Chan FY, Robinson J, Brownlie A, Shivdasani RA, Donovan A, Brugnara C, Kim J, Lau BC, Witkowska HE, Zon LI
published in: Blood
information resource reference: Characterization of adult alpha- and beta-globin genes in the zebrafish. Blood. 1997 Jan 15; 89(2):688-700.
journal title abbreviation: Blood
publication date: 1997-01-15T00:00:00
year: 1997
type: Academic Article
type: Article
type: Document
type: Information Resource

Characterization of the hematopoietic transcription factor NF-E2 in primary murine megakaryocytes.
PubMed Identifier: 9516460
author list: Lecine P, Blank V, Shivdasani R
published in: The Journal of biological chemistry
information resource reference: Characterization of the hematopoietic transcription factor NF-E2 in primary murine megakaryocytes. J Biol Chem. 1998 Mar 27; 273(13):7572-8.
journal title abbreviation: J Biol Chem
publication date: 1998-03-27T00:00:00
year: 1998
type: Academic Article
type: Article
type: Document
type: Information Resource

A Phase II study of gemcitabine and docetaxel in patients with metastatic pancreatic carcinoma.
PubMed Identifier: 11815964
author list: Ryan DP, Kulke MH, Fuchs CS, Grossbard ML, Grossman SR, Morgan JA, Earle CC, Shivdasani R, Kim H, Mayer RJ, Clark JW
published in: Cancer
information resource reference: A Phase II study of gemcitabine and docetaxel in patients with metastatic pancreatic carcinoma. Cancer. 2002 Jan 01; 94(1):97-103.
journal title abbreviation: Cancer
publication date: 2002-01-01T00:00:00
year: 2002
type: Academic Article
type: Article
type: Document
type: Information Resource

Regulation of mammalian epithelial differentiation and intestine development by class I histone deacetylases.
PubMed Identifier: 15060137
author list: Tou L, Liu Q, Shivdasani RA
published in: Molecular and cellular biology
information resource reference: Regulation of mammalian epithelial differentiation and intestine development by class I histone deacetylases. Mol Cell Biol. 2004 Apr; 24(8):3132-9.
journal title abbreviation: Mol Cell Biol
publication date: 2004-04-01T00:00:00
year: 2004
type: Academic Article
type: Article
type: Document
type: Information Resource

Small-molecule antagonists of the oncogenic Tcf/beta-catenin protein complex.
PubMed Identifier: 14749129
author list: Lepourcelet M, Chen YN, France DS, Wang H, Crews P, Petersen F, Bruseo C, Wood AW, Shivdasani RA
published in: Cancer cell
information resource reference: Small-molecule antagonists of the oncogenic Tcf/beta-catenin protein complex. Cancer Cell. 2004 Jan; 5(1):91-102.
journal title abbreviation: Cancer Cell
publication date: 2004-01-01T00:00:00
year: 2004
type: Academic Article
type: Article
type: Document
type: Information Resource

Phases of canonical Wnt signaling during the development of mouse intestinal epithelium.
PubMed Identifier: 17681174
author list: Kim BM, Mao J, Taketo MM, Shivdasani RA
published in: Gastroenterology
information resource reference: Phases of canonical Wnt signaling during the development of mouse intestinal epithelium. Gastroenterology. 2007 Aug; 133(2):529-38.
journal title abbreviation: Gastroenterology
publication date: 2007-05-03T00:00:00
year: 2007
type: Academic Article
type: Article
type: Document
type: Information Resource

Management of extragonadal germ cell tumors
author list: Leibowitz SB, Shivdasani RA, Kantoff PW
published in: In: Raghavan D, editor. American Cancer Society Atlas of Clinical Oncology - Germ Cell Tumors.
information resource reference: Management of extragonadal germ cell tumors. In: Raghavan D, editor. American Cancer Society Atlas of Clinical Oncology - Germ Cell Tumors. 2003; 243-64.
publication date: 2003-01-01T00:00:00
year: 2003
type: Academic Article
type: Article
type: Document
type: Information Resource

A lineage-selective knockout establishes the critical role of transcription factor GATA-1 in megakaryocyte growth and platelet development.
PubMed Identifier: 9233806
author list: Shivdasani RA, Fujiwara Y, McDevitt MA, Orkin SH
published in: The EMBO journal
information resource reference: A lineage-selective knockout establishes the critical role of transcription factor GATA-1 in megakaryocyte growth and platelet development. EMBO J. 1997 Jul 01; 16(13):3965-73.
journal title abbreviation: EMBO J
publication date: 1997-07-01T00:00:00
year: 1997
type: Academic Article
type: Article
type: Document
type: Information Resource

Blood platelets are assembled principally at the ends of proplatelet processes produced by differentiated megakaryocytes.
PubMed Identifier: 10601342
author list: Italiano JE, Lecine P, Shivdasani RA, Hartwig JH
published in: The Journal of cell biology
information resource reference: Blood platelets are assembled principally at the ends of proplatelet processes produced by differentiated megakaryocytes. J Cell Biol. 1999 Dec 13; 147(6):1299-312.
journal title abbreviation: J Cell Biol
publication date: 1999-12-13T00:00:00
year: 1999
type: Academic Article
type: Article
type: Document
type: Information Resource

Transcription factor GATA-1 in megakaryocyte development.
PubMed Identifier: 11012179
author list: Orkin SH, Shivdasani RA, Fujiwara Y, McDevitt MA
published in: Stem cells (Dayton, Ohio)
information resource reference: Transcription factor GATA-1 in megakaryocyte development. Stem Cells. 1998; 16 Suppl 2:79-83.
journal title abbreviation: Stem Cells
publication date: 1998-01-01T00:00:00
year: 1998
type: Academic Article
type: Article
type: Document
type: Information Resource

Dynamic visualization of thrombopoiesis within bone marrow.
PubMed Identifier: 17885137
author list: Junt T, Schulze H, Chen Z, Massberg S, Goerge T, Krueger A, Wagner DD, Graf T, Italiano JE, Shivdasani RA, von Andrian UH
published in: Science (New York, N.Y.)
information resource reference: Dynamic visualization of thrombopoiesis within bone marrow. Science. 2007 Sep 21; 317(5845):1767-70.
journal title abbreviation: Science
publication date: 2007-09-21T00:00:00
year: 2007
type: Academic Article
type: Article
type: Document
type: Information Resource

Complexity of CNC transcription factors as revealed by gene targeting of the Nrf3 locus.
PubMed Identifier: 15060151
author list: Derjuga A, Gourley TS, Holm TM, Heng HH, Shivdasani RA, Ahmed R, Andrews NC, Blank V
published in: Molecular and cellular biology
information resource reference: Complexity of CNC transcription factors as revealed by gene targeting of the Nrf3 locus. Mol Cell Biol. 2004 Apr; 24(8):3286-94.
journal title abbreviation: Mol Cell Biol
publication date: 2004-04-01T00:00:00
year: 2004
type: Academic Article
type: Article
type: Document
type: Information Resource

The Stem Cell Discovery Engine: an integrated repository and analysis system for cancer stem cell comparisons.
PubMed Identifier: 22121217
author list: Ho Sui SJ, Begley K, Reilly D, Chapman B, McGovern R, Rocca-Sera P, Maguire E, Altschuler GM, Hansen TA, Sompallae R, Krivtsov A, Shivdasani RA, Armstrong SA, Culhane AC, Correll M, Sansone SA, Hofmann O, Hide W
published in: Nucleic acids research
information resource reference: The Stem Cell Discovery Engine: an integrated repository and analysis system for cancer stem cell comparisons. Nucleic Acids Res. 2012 Jan; 40(Database issue):D984-91.
journal title abbreviation: Nucleic Acids Res
publication date: 2011-11-24T00:00:00
year: 2011
type: Academic Article
type: Article
type: Document
type: Information Resource

Brief report: graft-versus-host disease associated with transfusion of blood from unrelated HLA-homozygous donors.
PubMed Identifier: 8437597
author list: Shivdasani RA, Haluska FG, Dock NL, Dover JS, Kineke EJ, Anderson KC
published in: The New England journal of medicine
information resource reference: Brief report: graft-versus-host disease associated with transfusion of blood from unrelated HLA-homozygous donors. N Engl J Med. 1993 Mar 18; 328(11):766-70.
journal title abbreviation: N Engl J Med
publication date: 1993-03-18T00:00:00
year: 1993
type: Academic Article
type: Article
type: Document
type: Information Resource

The transcriptional control of hematopoiesis.
PubMed Identifier: 8639758
author list: Shivdasani RA, Orkin SH
published in: Blood
information resource reference: The transcriptional control of hematopoiesis. Blood. 1996 May 15; 87(10):4025-39.
journal title abbreviation: Blood
publication date: 1996-05-15T00:00:00
year: 1996
type: Academic Article
type: Article
type: Document
type: Information Resource

MicroRNAs: regulators of gene expression and cell differentiation.
PubMed Identifier: 16882713
author list: Shivdasani RA
published in: Blood
information resource reference: MicroRNAs: regulators of gene expression and cell differentiation. Blood. 2006 Dec 01; 108(12):3646-53.
journal title abbreviation: Blood
publication date: 2006-08-01T00:00:00
year: 2006
type: Academic Article
type: Article
type: Document
type: Information Resource

Intact function of Lgr5 receptor-expressing intestinal stem cells in the absence of Paneth cells.
PubMed Identifier: 22355124
author list: Kim TH, Escudero S, Shivdasani RA
published in: Proceedings of the National Academy of Sciences of the United States of America
information resource reference: Intact function of Lgr5 receptor-expressing intestinal stem cells in the absence of Paneth cells. Proc Natl Acad Sci U S A. 2012 Mar 06; 109(10):3932-7.
journal title abbreviation: Proc Natl Acad Sci U S A
publication date: 2012-02-21T00:00:00
year: 2012
type: Academic Article
type: Article
type: Document
type: Information Resource

Targeted disruption of the BCL9/ß-catenin complex inhibits oncogenic Wnt signaling.
PubMed Identifier: 22914623
author list: Takada K, Zhu D, Bird GH, Sukhdeo K, Zhao JJ, Mani M, Lemieux M, Carrasco DE, Ryan J, Horst D, Fulciniti M, Munshi NC, Xu W, Kung AL, Shivdasani RA, Walensky LD, Carrasco DR
published in: Science translational medicine
information resource reference: Targeted disruption of the BCL9/ß-catenin complex inhibits oncogenic Wnt signaling. Sci Transl Med. 2012 Aug 22; 4(148):148ra117.
journal title abbreviation: Sci Transl Med
publication date: 2012-08-22T00:00:00
year: 2012
type: Academic Article
type: Article
type: Document
type: Information Resource

High-resolution analysis of genetic alterations in small bowel carcinoid tumors reveals areas of recurrent amplification and loss
author list: Kulke MH, Freed E, Chiang D, Philips J, Zahrieh D, Glickman JN, Shivdasani RA
published in: Genes Chrom Cancer
information resource reference: High-resolution analysis of genetic alterations in small bowel carcinoid tumors reveals areas of recurrent amplification and loss. Genes Chrom Cancer. 2008; 47:591-603.
publication date: 2008-01-01T00:00:00
year: 2008
type: Academic Article
type: Article
type: Document
type: Information Resource

RanBP10 is a cytoplasmic guanine nucleotide exchange factor that modulates noncentrosomal microtubules.
PubMed Identifier: 18347012
author list: Schulze H, Dose M, Korpal M, Meyer I, Italiano JE, Shivdasani RA
published in: The Journal of biological chemistry
information resource reference: RanBP10 is a cytoplasmic guanine nucleotide exchange factor that modulates noncentrosomal microtubules. J Biol Chem. 2008 May 16; 283(20):14109-19.
journal title abbreviation: J Biol Chem
publication date: 2008-03-17T00:00:00
year: 2008
type: Academic Article
type: Article
type: Document
type: Information Resource

Prognostic and predictive value of common mutations for treatment response and survival in patients with metastatic colorectal cancer.
PubMed Identifier: 19603024
author list: Souglakos J, Philips J, Wang R, Marwah S, Silver M, Tzardi M, Silver J, Ogino S, Hooshmand S, Kwak E, Freed E, Meyerhardt JA, Saridaki Z, Georgoulias V, Finkelstein D, Fuchs CS, Kulke MH, Shivdasani RA
published in: British journal of cancer
information resource reference: Prognostic and predictive value of common mutations for treatment response and survival in patients with metastatic colorectal cancer. Br J Cancer. 2009 Aug 04; 101(3):465-72.
journal title abbreviation: Br J Cancer
publication date: 2009-07-14T00:00:00
year: 2009
type: Academic Article
type: Article
type: Document
type: Information Resource

450 Brookline Ave
type: Address
address line 1: Dana-Farber Cancer Institute
address line 2: Medical Oncology
address line 3: 450 Brookline Ave
city: Boston
postal code: 02215
state or province: MA

GEFs on the RhoAd to a colossal nucleus.
PubMed Identifier: 22421037
author list: Shivdasani RA
published in: Developmental cell
information resource reference: GEFs on the RhoAd to a colossal nucleus. Dev Cell. 2012 Mar 13; 22(3):471-2.
journal title abbreviation: Dev Cell
publication date: 2012-03-13T00:00:00
year: 2012
type: Academic Article
type: Article
type: Document
type: Information Resource

Transfusion-associated graft-versus-host disease: scratching the surface.
PubMed Identifier: 8212111
author list: Shivdasani RA, Anderson KC
published in: Transfusion
information resource reference: Transfusion-associated graft-versus-host disease: scratching the surface. Transfusion. 1993 Sep; 33(9):696-7.
journal title abbreviation: Transfusion
publication date: 1993-09-01T00:00:00
year: 1993
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1037648
type: Authorship
author rank in publication: 6
linked author: Shivdasani, Ramesh
linked information resource: Transcription factor-dependent 'anti-repressive' mammalian enhancers exclude H3K27me3 from extended genomic domains.

Transcription factor-dependent 'anti-repressive' mammalian enhancers exclude H3K27me3 from extended genomic domains.
PubMed Identifier: 29321178
author list: Saxena M, Roman AKS, O'Neill NK, Sulahian R, Jadhav U, Shivdasani RA
published in: Genes & development
information resource reference: Transcription factor-dependent 'anti-repressive' mammalian enhancers exclude H3K27me3 from extended genomic domains. Genes Dev. 2017 12 01; 31(23-24):2391-2404.
journal title abbreviation: Genes Dev
publication date: 2017-12-01T00:00:00
year: 2017
type: Academic Article
type: Article
type: Document
type: Information Resource

Gastric epithelial stem cells.
PubMed Identifier: 21144849
author list: Mills JC, Shivdasani RA
published in: Gastroenterology
information resource reference: Gastric epithelial stem cells. Gastroenterology. 2011 Feb; 140(2):412-24.
journal title abbreviation: Gastroenterology
publication date: 2010-12-07T00:00:00
year: 2010
type: Academic Article
type: Article
type: Document
type: Information Resource

Role of the homeodomain transcription factor Bapx1 in mouse distal stomach development.
PubMed Identifier: 19208343
author list: Verzi MP, Stanfel MN, Moses KA, Kim BM, Zhang Y, Schwartz RJ, Shivdasani RA, Zimmer WE
published in: Gastroenterology
information resource reference: Role of the homeodomain transcription factor Bapx1 in mouse distal stomach development. Gastroenterology. 2009 May; 136(5):1701-10.
journal title abbreviation: Gastroenterology
publication date: 2009-01-14T00:00:00
year: 2009
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 101532
type: Authorship
author rank in publication: 3
linked author: Shivdasani, Ramesh
linked information resource: Structure of a human Tcf4-beta-catenin complex.

Stem cell transcription factors.
PubMed Identifier: 9443052
author list: Shivdasani RA
published in: Hematology/oncology clinics of North America
information resource reference: Stem cell transcription factors. Hematol Oncol Clin North Am. 1997 Dec; 11(6):1199-206.
journal title abbreviation: Hematol Oncol Clin North Am
publication date: 1997-12-01T00:00:00
year: 1997
type: Academic Article
type: Article
type: Document
type: Information Resource

p45 NF-E2 regulates expression of thromboxane synthase in megakaryocytes.
PubMed Identifier: 9312024
author list: Deveaux S, Cohen-Kaminsky S, Shivdasani RA, Andrews NC, Filipe A, Kuzniak I, Orkin SH, Roméo PH, Mignotte V
published in: The EMBO journal
information resource reference: p45 NF-E2 regulates expression of thromboxane synthase in megakaryocytes. EMBO J. 1997 Sep 15; 16(18):5654-61.
journal title abbreviation: EMBO J
publication date: 1997-09-15T00:00:00
year: 1997
type: Academic Article
type: Article
type: Document
type: Information Resource

Pathophysiology of thrombocytopenia and anemia in mice lacking transcription factor NF-E2.
PubMed Identifier: 10556187
author list: Levin J, Peng JP, Baker GR, Villeval JL, Lecine P, Burstein SA, Shivdasani RA
published in: Blood
information resource reference: Pathophysiology of thrombocytopenia and anemia in mice lacking transcription factor NF-E2. Blood. 1999 Nov 01; 94(9):3037-47.
journal title abbreviation: Blood
publication date: 1999-11-01T00:00:00
year: 1999
type: Academic Article
type: Article
type: Document
type: Information Resource

Structure of a human Tcf4-beta-catenin complex.
PubMed Identifier: 11713476
author list: Poy F, Lepourcelet M, Shivdasani RA, Eck MJ
published in: Nature structural biology
information resource reference: Structure of a human Tcf4-beta-catenin complex. Nat Struct Biol. 2001 Dec; 8(12):1053-7.
journal title abbreviation: Nat Struct Biol
publication date: 2001-12-01T00:00:00
year: 2001
type: Academic Article
type: Article
type: Document
type: Information Resource

Erythroid maturation and globin gene expression in mice with combined deficiency of NF-E2 and nrf-2.
PubMed Identifier: 9558405
author list: Martin F, van Deursen JM, Shivdasani RA, Jackson CW, Troutman AG, Ney PA
published in: Blood
information resource reference: Erythroid maturation and globin gene expression in mice with combined deficiency of NF-E2 and nrf-2. Blood. 1998 May 01; 91(9):3459-66.
journal title abbreviation: Blood
publication date: 1998-05-01T00:00:00
year: 1998
type: Academic Article
type: Article
type: Document
type: Information Resource

Genetics and diet regulate vitamin A production via the homeobox transcription factor ISX.
PubMed Identifier: 23393141
author list: Lobo GP, Amengual J, Baus D, Shivdasani RA, Taylor D, von Lintig J
published in: The Journal of biological chemistry
information resource reference: Genetics and diet regulate vitamin A production via the homeobox transcription factor ISX. J Biol Chem. 2013 Mar 29; 288(13):9017-27.
journal title abbreviation: J Biol Chem
publication date: 2013-02-07T00:00:00
year: 2013
type: Academic Article
type: Article
type: Document
type: Information Resource

Culture and in vitro differentiation of murine megakaryocytes
author list: Schulze, Shivdasani RA
published in: In: Coligan JE, Bierer BE, Margulies DH, Shevach EM, Strober W, editors. Current protocols in immunology.
information resource reference: Culture and in vitro differentiation of murine megakaryocytes. In: Coligan JE, Bierer BE, Margulies DH, Shevach EM, Strober W, editors. Current protocols in immunology. 2005; Chapter 22F:6.1-6.13.
publication date: 2005-01-01T00:00:00
year: 2005
type: Academic Article
type: Article
type: Document
type: Information Resource

Hematopoietic-specific beta 1 tubulin participates in a pathway of platelet biogenesis dependent on the transcription factor NF-E2.
PubMed Identifier: 10942379
author list: Lecine P, Italiano JE, Kim SW, Villeval JL, Shivdasani RA
published in: Blood
information resource reference: Hematopoietic-specific beta 1 tubulin participates in a pathway of platelet biogenesis dependent on the transcription factor NF-E2. Blood. 2000 Aug 15; 96(4):1366-73.
journal title abbreviation: Blood
publication date: 2000-08-15T00:00:00
year: 2000
type: Academic Article
type: Article
type: Document
type: Information Resource

Toward mechanism-based cancer care.
PubMed Identifier: 11176864
author list: Livingston DM, Shivdasani R
published in: JAMA
information resource reference: Toward mechanism-based cancer care. JAMA. 2001 Feb 07; 285(5):588-93.
journal title abbreviation: JAMA
publication date: 2001-02-07T00:00:00
year: 2001
type: Academic Article
type: Article
type: Document
type: Information Resource

RORa-expressing T regulatory cells restrain allergic skin inflammation.
PubMed Identifier: 29500225
author list: Malhotra N, Leyva-Castillo JM, Jadhav U, Barreiro O, Kam C, O'Neill NK, Meylan F, Chambon P, von Andrian UH, Siegel RM, Wang EC, Shivdasani R, Geha RS
published in: Science immunology
information resource reference: RORa-expressing T regulatory cells restrain allergic skin inflammation. Sci Immunol. 2018 03 02; 3(21).
journal title abbreviation: Sci Immunol
publication date: 2018-03-02T00:00:00
year: 2018
type: Academic Article
type: Article
type: Document
type: Information Resource