Charlotte F. and Irving W. Rabb Distinguished Professor of Medicine
He D, Sougioultzis S, Hagen S, Liu J, Keates S, Keates AC, Pothoulakis C, Lamont JT
Clostridium difficile toxin A triggers human colonocyte IL-8 release via mitochondrial oxygen radical generation. Gastroenterology. 2002 Apr; 122(4):1048-57.
Clostridium difficile toxin A triggers human colonocyte IL-8 release via mitochondrial oxygen radical generation.
Lamont JT, Perrotto JL, Weiser MM, Isselbacher KJ
Proceedings of the National Academy of Sciences of the United States of America
Cell surface galactosyltransferase and lectin agglutination of thymus and spleen lymphocytes. Proc Natl Acad Sci U S A. 1974 Sep; 71(9):3726-30.
Cell surface galactosyltransferase and lectin agglutination of thymus and spleen lymphocytes.
Leung DY, Kelly CP, Boguniewicz M, Pothoulakis C, LaMont JT, Flores A
Treatment with intravenously administered gamma globulin of chronic relapsing colitis induced by Clostridium difficile toxin. J Pediatr. 1991 Apr; 118(4 Pt 1):633-7.
Treatment with intravenously administered gamma globulin of chronic relapsing colitis induced by Clostridium difficile toxin.
Kim H, Rhee SH, Pothoulakis C, LaMont JT
Clostridium difficile toxin A binds colonocyte Src causing dephosphorylation of focal adhesion kinase and paxillin. Exp Cell Res. 2009 Nov 15; 315(19):3336-44.
Clostridium difficile toxin A binds colonocyte Src causing dephosphorylation of focal adhesion kinase and paxillin.
Triadafilopoulos G, Pothoulakis C, O'Brien MJ, LaMont JT
Differential effects of Clostridium difficile toxins A and B on rabbit ileum. Gastroenterology. 1987 Aug; 93(2):273-9.
Differential effects of Clostridium difficile toxins A and B on rabbit ileum.
Pothoulakis H, Triadafilopoulos G, LaMont JT
Antibiotic-associated colitis. Compr Ther. 1985 Dec; 11(12):68-73.
Aspirin prevention of cholesterol gallstone formation in prairie dogs. Science. 1981 Mar 27; 211(4489):1429-31.
Aspirin prevention of cholesterol gallstone formation in prairie dogs.
Qiu B, Pothoulakis C, Castagliuolo I, Nikulasson S, LaMont JT
Participation of reactive oxygen metabolites in Clostridium difficile toxin A-induced enteritis in rats. Am J Physiol. 1999 02; 276(2):G485-90.
Participation of reactive oxygen metabolites in Clostridium difficile toxin A-induced enteritis in rats.
He D, Hagen SJ, Pothoulakis C, Chen M, Medina ND, Warny M, LaMont JT
Clostridium difficile toxin A causes early damage to mitochondria in cultured cells. Gastroenterology. 2000 Jul; 119(1):139-50.
Clostridium difficile toxin A causes early damage to mitochondria in cultured cells.
Clostridium difficile diarrhea: pathogenesis, epidemiology, and treatment. Gastroenterologist. 1994 Mar; 2(1):61-9.
Clostridium difficile diarrhea: pathogenesis, epidemiology, and treatment.
Pothoulakis C, Kelly CP, Joshi MA, Gao N, O'Keane CJ, Castagliuolo I, Lamont JT
Saccharomyces boulardii inhibits Clostridium difficile toxin A binding and enterotoxicity in rat ileum. Gastroenterology. 1993 Apr; 104(4):1108-15.
Saccharomyces boulardii inhibits Clostridium difficile toxin A binding and enterotoxicity in rat ileum.
Screening virtual colonoscopy--ready for prime time? N Engl J Med. 2003 Dec 04; 349(23):2261-4.
Screening virtual colonoscopy--ready for prime time?
LaMont JT, Turner BS, Bernstein SE, Trotman B
Gallbladder glycoprotein secretion in mice with hemolytic anemia and pigment gallstones. Hepatology. 1983 Mar-Apr; 3(2):198-200.
Gallbladder glycoprotein secretion in mice with hemolytic anemia and pigment gallstones.
Laboratory investigation; a journal of technical methods and pathology
The sequence of events in gallstone formation. Lab Invest. 1987 Feb; 56(2):125-6.
The sequence of events in gallstone formation.
Turner BS, Bhaskar KR, Hadzopoulou-Cladaras M, Specian RD, LaMont JT
Isolation and characterization of cDNA clones encoding pig gastric mucin. Biochem J. 1995 May 15; 308 ( Pt 1):89-96.
Isolation and characterization of cDNA clones encoding pig gastric mucin.
Pothoulakis C, Castagliuolo I, Kelly CP, Lamont JT
International journal of antimicrobial agents
Clostridium difficile-associated diarrhea and colitis: pathogenesis and therapy. Int J Antimicrob Agents. 1993 Jul; 3(1):17-32.
Clostridium difficile-associated diarrhea and colitis: pathogenesis and therapy.
Juul FE, Garborg K, Bretthauer M, Skudal H, Øines MN, Wiig H, Rose Ø, Seip B, Lamont JT, Midtvedt T, Valeur J, Kalager M, Holme Ø, Helsingen L, Løberg M, Adami HO
Fecal Microbiota Transplantation for Primary Clostridium difficile Infection. N Engl J Med. 2018 06 28; 378(26):2535-2536.
Fecal Microbiota Transplantation for Primary Clostridium difficile Infection.
Pathophysiology, diagnosis and treatment of Clostridium difficile infection. Keio J Med. 1999 Dec; 48(4):169-74.
Pathophysiology, diagnosis and treatment of Clostridium difficile infection.
Editorial: Alpha 1-antitrypsin deficiency - a defect of secretion. N Engl J Med. 1975 Jan 23; 292(4):205-6.
Editorial: Alpha 1-antitrypsin deficiency - a defect of secretion.
Katz L, LaMont JT, Trier JS, Sonnenblick EB, Rothman SW, Broitman SA, Rieth S
Experimental clindamycin-associated colitis in rabbits. Evidence of toxin-mediated mucosal damage. Gastroenterology. 1978 Feb; 74(2 Pt 1):246-52.
Experimental clindamycin-associated colitis in rabbits. Evidence of toxin-mediated mucosal damage.
Galactosyltransferase in fetal, neonatal, and adult colon: relationship to differentiation. Am J Physiol. 1978 Aug; 235(2):E213-7.
Galactosyltransferase in fetal, neonatal, and adult colon: relationship to differentiation.
Human gallbladder mucin accelerates nucleation of cholesterol in artificial bile. Gastroenterology. 1984 Aug; 87(2):270-5.
Human gallbladder mucin accelerates nucleation of cholesterol in artificial bile.
Bovine gallbladder mucin binds bilirubin in vitro. Gastroenterology. 1983 Sep; 85(3):707-12.
Bovine gallbladder mucin binds bilirubin in vitro.
The central issue of cholesterol gallstones. Hepatology. 1986 May-Jun; 6(3):529-31.
The central issue of cholesterol gallstones.
Gilbert RJ, Triadafilopoulos G, Pothoulakis C, Giampaolo C, LaMont JT
Effect of purified Clostridium difficile toxins on intestinal smooth muscle. I. Toxin A. Am J Physiol. 1989 Apr; 256(4 Pt 1):G759-66.
Effect of purified Clostridium difficile toxins on intestinal smooth muscle. I. Toxin A.
Oxygen radicals stimulate guinea pig gallbladder glycoprotein secretion in vitro. Am J Physiol. 1987 Nov; 253(5 Pt 1):G627-30.
Oxygen radicals stimulate guinea pig gallbladder glycoprotein secretion in vitro.
Significance of occult gastrointestinal bleeding during anticoagulation therapy. Am J Med. 1987 Aug; 83(2):269-72.
Significance of occult gastrointestinal bleeding during anticoagulation therapy.
Pothoulakis C, Barone LM, Ely R, Faris B, Clark ME, Franzblau C, LaMont JT
Purification and properties of Clostridium difficile cytotoxin B. J Biol Chem. 1986 Jan 25; 261(3):1316-21.
Purification and properties of Clostridium difficile cytotoxin B.
Recommendations for inflammatory bowel disease. Geriatrics. 1982 Mar; 37(3):93-6, 102, 105.
Recommendations for inflammatory bowel disease.
Gilbert RJ, Pothoulakis C, LaMont JT, Yakubovich M
Clostridium difficile toxin B activates calcium influx required for actin disassembly during cytotoxicity. Am J Physiol. 1995 Mar; 268(3 Pt 1):G487-95.
Clostridium difficile toxin B activates calcium influx required for actin disassembly during cytotoxicity.
The Mount Sinai journal of medicine, New York
Clostridium difficile colitis: epidemiology, pathophysiology, and treatment. Mt Sinai J Med. 1994 Sep; 61(4):329-35.
Clostridium difficile colitis: epidemiology, pathophysiology, and treatment.
Identification of gallbladder mucin-bilirubin complex in human cholesterol gallstone matrix. Effects of reducing agents on in vitro dissolution of matrix and intact gallstones. J Clin Invest. 1985 Aug; 76(2):439-45.
Identification of gallbladder mucin-bilirubin complex in human cholesterol gallstone matrix. Effects of reducing agents on in vitro dissolution of matrix and intact gallstones.
Postoperative jaundice. N Engl J Med. 1973 Feb 08; 288(6):305-7.
LaMont JT, Turner BS, DiBenedetto D, Handin R, Schafer AI
Arachidonic acid stimulates mucin secretion in prairie dog gallbladder. Am J Physiol. 1983 Jul; 245(1):G92-8.
Arachidonic acid stimulates mucin secretion in prairie dog gallbladder.
Triadafilopoulos G, Pothoulakis C, Weiss R, Giampaolo C, Lamont JT
Comparative study of Clostridium difficile toxin A and cholera toxin in rabbit ileum. Gastroenterology. 1989 Nov; 97(5):1186-92.
Comparative study of Clostridium difficile toxin A and cholera toxin in rabbit ileum.
Qiu B, Pothoulakis C, Castagliuolo I, Nikulasson Z, LaMont JT
Nitric oxide inhibits rat intestinal secretion by Clostridium difficile toxin A but not Vibrio cholerae enterotoxin. Gastroenterology. 1996 Aug; 111(2):409-18.
Nitric oxide inhibits rat intestinal secretion by Clostridium difficile toxin A but not Vibrio cholerae enterotoxin.
Hecht G, Pothoulakis C, LaMont JT, Madara JL
Clostridium difficile toxin A perturbs cytoskeletal structure and tight junction permeability of cultured human intestinal epithelial monolayers. J Clin Invest. 1988 Nov; 82(5):1516-24.
Clostridium difficile toxin A perturbs cytoskeletal structure and tight junction permeability of cultured human intestinal epithelial monolayers.
Clostridium difficile colitis. N Engl J Med. 1994 Jan 27; 330(4):257-62.
Clostridium difficile--more difficult than ever. N Engl J Med. 2008 Oct 30; 359(18):1932-40.
Clostridium difficile--more difficult than ever.
Pothoulakis C, Triadafilopoulos G, Clark M, Franzblau C, LaMont JT
Clostridium difficile cytotoxin inhibits protein synthesis in fibroblasts and intestinal mucosa. Gastroenterology. 1986 Nov; 91(5):1147-53.
Clostridium difficile cytotoxin inhibits protein synthesis in fibroblasts and intestinal mucosa.
Differentiation of glycoprotein synthesis in fetal rat colon. Am J Physiol. 1978 Aug; 235(2):E207-12.
Differentiation of glycoprotein synthesis in fetal rat colon.
Counterimmunoelectrophoresis vs. cytotoxicity assay for the detection of Clostridium difficile toxin. J Infect Dis. 1982 Mar; 145(3):398.
Counterimmunoelectrophoresis vs. cytotoxicity assay for the detection of Clostridium difficile toxin.
Pothoulakis C, Gilbert RJ, Cladaras C, Castagliuolo I, Semenza G, Hitti Y, Montcrief JS, Linevsky J, Kelly CP, Nikulasson S, Desai HP, Wilkins TD, LaMont JT
Rabbit sucrase-isomaltase contains a functional intestinal receptor for Clostridium difficile toxin A. J Clin Invest. 1996 Aug 01; 98(3):641-9.
Rabbit sucrase-isomaltase contains a functional intestinal receptor for Clostridium difficile toxin A.
Lamont JT, Ventola AS, Maull EA, Szabo S
Cysteamine and prostaglandin F2 beta stimulate rat gastric mucin release. Gastroenterology. 1983 Feb; 84(2):306-13.
Cysteamine and prostaglandin F2 beta stimulate rat gastric mucin release.
Clostridium difficile infection. Annu Rev Med. 1998; 49:375-90.
Afdhal NH, Gong D, Niu N, Turner B, LaMont JT, Offner GD
Cholesterol cholelithiasis in the prairie dog: role of mucin and nonmucin glycoproteins. Hepatology. 1993 Apr; 17(4):693-700.
Cholesterol cholelithiasis in the prairie dog: role of mucin and nonmucin glycoproteins.
Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association
A 69-year-old woman presenting to the hospital with 48 hours of abdominal pain and diarrhea. Clin Gastroenterol Hepatol. 2009 Oct; 7(10):1046-8.
A 69-year-old woman presenting to the hospital with 48 hours of abdominal pain and diarrhea.
Symposia of the Society for Experimental Biology
Oxygen radicals stimulate gallbladder glycoprotein secretion. Symp Soc Exp Biol. 1989; 43:273-8.
Oxygen radicals stimulate gallbladder glycoprotein secretion.
Leffler DA, Kheraj R, Bhansali A, Yamanaka H, Neeman N, Sheth S, Sawhney M, Lamont JT, Aronson MD
Adenoma detection rates vary minimally with time of day and case rank: a prospective study of 2139 first screening colonoscopies. Gastrointest Endosc. 2012 Mar; 75(3):554-60.
Adenoma detection rates vary minimally with time of day and case rank: a prospective study of 2139 first screening colonoscopies.
Murray FE, O'Brien MJ, Birkett DH, Kennedy SM, LaMont JT
Diversion colitis. Pathologic findings in a resected sigmoid colon and rectum. Gastroenterology. 1987 Dec; 93(6):1404-8.
Diversion colitis. Pathologic findings in a resected sigmoid colon and rectum.
Hydrocortisone inhibits mucin secretion from guinea pig gallbladder. Am J Physiol. 1984 Oct; 247(4 Pt 1):G427-31.
Hydrocortisone inhibits mucin secretion from guinea pig gallbladder.
Stambler JB, Klibaner MI, Bliss CM, LaMont JT
Tuberculous abscess of the pancreas. Gastroenterology. 1982 Oct; 83(4):922-5.
Glycoprotein synthesis and secretion in human colon cancers and normal colonic mucosa. Cancer Res. 1978 Sep; 38(9):2784-9.
Glycoprotein synthesis and secretion in human colon cancers and normal colonic mucosa.
Role of gallbladder mucin in pathophysiology of gallstones. Hepatology. 1984 Sep-Oct; 4(5 Suppl):51S-56S.
Role of gallbladder mucin in pathophysiology of gallstones.
Pothoulakis C, Castagliuolo I, LaMont JT, Jaffer A, O'Keane JC, Snider RM, Leeman SE
CP-96,345, a substance P antagonist, inhibits rat intestinal responses to Clostridium difficile toxin A but not cholera toxin. Proc Natl Acad Sci U S A. 1994 Feb 01; 91(3):947-51.
CP-96,345, a substance P antagonist, inhibits rat intestinal responses to Clostridium difficile toxin A but not cholera toxin.
Riegler M, Sedivy R, Pothoulakis C, Hamilton G, Zacherl J, Bischof G, Cosentini E, Feil W, Schiessel R, LaMont JT
Clostridium difficile toxin B is more potent than toxin A in damaging human colonic epithelium in vitro. J Clin Invest. 1995 May; 95(5):2004-11.
Clostridium difficile toxin B is more potent than toxin A in damaging human colonic epithelium in vitro.
Why fibre is good for you. Lancet. 1994 Feb 12; 343(8894):372.
Kelly CP, Becker S, Linevsky JK, Joshi MA, O'Keane JC, Dickey BF, LaMont JT, Pothoulakis C
Neutrophil recruitment in Clostridium difficile toxin A enteritis in the rabbit. J Clin Invest. 1994 Mar; 93(3):1257-65.
Neutrophil recruitment in Clostridium difficile toxin A enteritis in the rabbit.
Probiotics for Children with Gastroenteritis. N Engl J Med. 2018 11 22; 379(21):2076-2077.
Probiotics for Children with Gastroenteritis.
Beubler E, Schirgi-Degen A, Pabst MA, Pothoulakis C, LaMont JT
Effects of purified Clostridium difficile toxin A in the small intestine of the rat in vivo. Nat Toxins. 1993; 1(6):369-75.
Effects of purified Clostridium difficile toxin A in the small intestine of the rat in vivo.
Journal of the National Cancer Institute
Alterations in glycosyltransferase activity in human colon cancer. J Natl Cancer Inst. 1975 Jan; 54(1):53-56.
Alterations in glycosyltransferase activity in human colon cancer.
Current concepts of postoperative hepatic dysfunction. Conn Med. 1975 Aug; 39(8):461-4.
Current concepts of postoperative hepatic dysfunction.
Castagliuolo I, LaMont JT, Qiu B, Nikulasson ST, Pothoulakis C
A receptor decoy inhibits the enterotoxic effects of Clostridium difficile toxin A in rat ileum. Gastroenterology. 1996 Aug; 111(2):433-8.
A receptor decoy inhibits the enterotoxic effects of Clostridium difficile toxin A in rat ileum.
Lazar HL, McCormick JR, Lamont JT, Bell R
Dysphagia lusoria associated with an esophageal carcinoma. Ann Thorac Surg. 1987 Sep; 44(3):315-7.
Dysphagia lusoria associated with an esophageal carcinoma.
Haemolysis in experimental cholestasis: possible role of erythrocyte sialic acid. Gut. 1974 Oct; 15(10):794-8.
Haemolysis in experimental cholestasis: possible role of erythrocyte sialic acid.
Postoperative juandice. Surg Clin North Am. 1974 Jun; 54(3):637-45.
Clostridium difficile colitis. Adv Intern Med. 1984; 29:85-107.
Advances in experimental medicine and biology
Gallbladder mucin glycoprotein hypersecretion in experimental cholelithiasis: role of mucin gel in nucleation of cholesterol gallstones. Adv Exp Med Biol. 1982; 144:231-4.
Gallbladder mucin glycoprotein hypersecretion in experimental cholelithiasis: role of mucin gel in nucleation of cholesterol gallstones.
Kang JK, Hwang JS, Nam HJ, Ahn KJ, Seok H, Kim SK, Yun EY, Pothoulakis C, Lamont JT, Kim H
The insect peptide coprisin prevents Clostridium difficile-mediated acute inflammation and mucosal damage through selective antimicrobial activity. Antimicrob Agents Chemother. 2011 Oct; 55(10):4850-7.
The insect peptide coprisin prevents Clostridium difficile-mediated acute inflammation and mucosal damage through selective antimicrobial activity.
LaMorte WW, LaMont JT, Hale W, Booker ML, Scott TE, Turner B
Gallbladder prostaglandins and lysophospholipids as mediators of mucin secretion during cholelithiasis. Am J Physiol. 1986 Nov; 251(5 Pt 1):G701-9.
Gallbladder prostaglandins and lysophospholipids as mediators of mucin secretion during cholelithiasis.
Ethics of renal biopsy. Ann Intern Med. 1974 Apr; 80(4):560.
Association of Clostridium difficile toxin with symptomatic relapse of chronic inflammatory bowel disease. Gastroenterology. 1981 Apr; 80(4):693-6.
Association of Clostridium difficile toxin with symptomatic relapse of chronic inflammatory bowel disease.
Synthesis and secretion of colonic glycoproteins: evidence for shedding in vivo of low molecular weight membrane components. Biochim Biophys Acta. 1980 May 22; 629(3):553-65.
Synthesis and secretion of colonic glycoproteins: evidence for shedding in vivo of low molecular weight membrane components.
Treatment of gastrointestinal infections. Gastroenterology. 2000 Feb; 118(2 Suppl 1):S48-67.
Treatment of gastrointestinal infections.
The effects of neuraminidase on concanavalin A agglutination of erythrocytes: evidence for adsorption of neuraminidase to erythrocyte membrane. J Cell Physiol. 1977 Mar; 90(3):565-72.
The effects of neuraminidase on concanavalin A agglutination of erythrocytes: evidence for adsorption of neuraminidase to erythrocyte membrane.
The pathogenesis of gallstones. Hosp Pract (Off Ed). 1984 Dec; 19(12):93-9, 103-4.
Gastroenterology clinics of North America
Clostridium difficile colitis and diarrhea. Gastroenterol Clin North Am. 1993 Sep; 22(3):623-37.
Clostridium difficile colitis and diarrhea.
PURIFICATION AND MECHANISM OF C. DIFFICILE TOXIN
Intestinal Mechanisms of C. difficile Toxins
INTESTINAL MECHANISMS OF C DIFFICILE TOXINS
STRUCTURE AND FUNCTION OF INTESTINAL MUCIN
Lamont J, Verbeken E, Verschakelen J, Demedts M
Bronchiolitis obliterans organising pneumonia. A report of 11 cases and a review of the literature. Acta Clin Belg. 1998 Oct; 53(5):328-36.
Bronchiolitis obliterans organising pneumonia. A report of 11 cases and a review of the literature.
Maude and Lillian Presley Professor of Microbiology and Immunobiology, Emeritus
Assistant Professor of Medicine, Part-time
Vianello E, Dozio E, Bandera F, Froldi M, Micaglio E, Lamont J, Tacchini L, Schmitz G, Corsi Romanelli MM
International journal of molecular sciences
Correlative Study on Impaired Prostaglandin E2 Regulation in Epicardial Adipose Tissue and its Role in Maladaptive Cardiac Remodeling via EPAC2 and ST2 Signaling in Overweight Cardiovascular Disease Subjects. Int J Mol Sci. 2020 01 14; 21(2).
Correlative Study on Impaired Prostaglandin E2 Regulation in Epicardial Adipose Tissue and its Role in Maladaptive Cardiac Remodeling via EPAC2 and ST2 Signaling in Overweight Cardiovascular Disease Subjects.
Small Bowel Diverticulosis: Pathogenesis, Clinical Management, and New Concepts. Curr Gastroenterol Rep. 2020 Jan 15; 22(1):4.
Small Bowel Diverticulosis: Pathogenesis, Clinical Management, and New Concepts.
Portincasa P, Di Ciaula A, Bonfrate L, Stella A, Garruti G, Lamont JT
Metabolic dysfunction-associated gallstone disease: expecting more from critical care manifestations. Intern Emerg Med. 2023 10; 18(7):1897-1918.
Metabolic dysfunction-associated gallstone disease: expecting more from critical care manifestations.
Bonfrate L, Giuliante F, Palasciano G, Lamont JT, Portincasa P
Unexpected discovery of massive liver echinococcosis. A clinical, morphological, and functional diagnosis. Ann Hepatol. 2013 Jul-Aug; 12(4):634-41.
Unexpected discovery of massive liver echinococcosis. A clinical, morphological, and functional diagnosis.
Journal of the American Geriatrics Society
Fecal transplantation for recurrent Clostridium difficile infection in older adults: a review. J Am Geriatr Soc. 2013 Aug; 61(8):1394-8.
Fecal transplantation for recurrent Clostridium difficile infection in older adults: a review.
Genetically engineered probiotics: a new twist on an old remedy. Gastroenterology. 2005 May; 128(5):1509-12.
Genetically engineered probiotics: a new twist on an old remedy.
Clostridium difficile infection: a worldwide disease. Gut Liver. 2014 Jan; 8(1):1-6.
Clostridium difficile infection: a worldwide disease.
Overview of Clostridium difficile infection: implications for China. Gastroenterol Rep (Oxf). 2013 Nov; 1(3):153-8.
Overview of Clostridium difficile infection: implications for China.
Rancier M, Zaaber I, Stathopoulou MG, Chatelin J, Saleh A, Marmouch H, El Shamieh S, Masson C, Murray H, Lamont J, Fitzgerald P, Mahjoub S, Said K, Tensaout BB, Mestiri S, Visvikis-Siest S
Pro- and anti-angiogenic VEGF mRNAs in autoimmune thyroid diseases. Autoimmunity. 2016 09; 49(6):366-372.
Pro- and anti-angiogenic VEGF mRNAs in autoimmune thyroid diseases.
Stathopoulou MG, Xie T, Ruggiero D, Chatelin J, Rancier M, Weryha G, Kurth MJ, Aldasoro Arguinano AA, Gorenjak V, Petrelis AM, Dagher G, Dedoussis G, Deloukas P, Lamont J, Marc J, Simmaco M, Schaik RHNV, Innocenti F, Merlin JL, Schneider J, Alizadeh BZ, Ciullo M, Seshadri S, Visvikis-Siest S
Clinical chemistry and laboratory medicine
A transnational collaborative network dedicated to the study and applications of the vascular endothelial growth factor-A in medical practice: the VEGF Consortium. Clin Chem Lab Med. 2018 03 28; 56(4):83-86.
A transnational collaborative network dedicated to the study and applications of the vascular endothelial growth factor-A in medical practice: the VEGF Consortium.
Choi SH, Ruggiero D, Sorice R, Song C, Nutile T, Vernon Smith A, Concas MP, Traglia M, Barbieri C, Ndiaye NC, Stathopoulou MG, Lagou V, Maestrale GB, Sala C, Debette S, Kovacs P, Lind L, Lamont J, Fitzgerald P, Tönjes A, Gudnason V, Toniolo D, Pirastu M, Bellenguez C, Vasan RS, Ingelsson E, Leutenegger AL, Johnson AD, DeStefano AL, Visvikis-Siest S, Seshadri S, Ciullo M
Six Novel Loci Associated with Circulating VEGF Levels Identified by a Meta-analysis of Genome-Wide Association Studies. PLoS Genet. 2016 Feb; 12(2):e1005874.
Six Novel Loci Associated with Circulating VEGF Levels Identified by a Meta-analysis of Genome-Wide Association Studies.
Zaaber I, Rancier M, Stathopoulou MG, Saleh A, Marmouch H, Masson C, Murray H, Kurth MJ, Lamont J, Fitzgerald P, Mahjoub S, Said K, Bel Hadj Jrad Tensaout B, Mestiri S, Visvikis-Siest S
Plasma VEGF-related polymorphisms are implied in autoimmune thyroid diseases. Autoimmunity. 2016 06; 49(4):229-35.
Plasma VEGF-related polymorphisms are implied in autoimmune thyroid diseases.
Amerikanou C, Kanoni S, Kaliora AC, Barone A, Bjelan M, D'Auria G, Gioxari A, Gosalbes MJ, Mouchti S, Stathopoulou MG, Soriano B, Stojanoski S, Banerjee R, Halabalaki M, Mikropoulou EV, Kannt A, Lamont J, Llorens C, Marascio F, Marascio M, Roig FJ, Smyrnioudis I, Varlamis I, Visvikis-Siest S, Vukic M, Milic N, Medic-Stojanoska M, Cesarini L, Campolo J, Gastaldelli A, Deloukas P, Trivella MG, Francino MP, Dedoussis GV
Effect of Mastiha supplementation on NAFLD: The MAST4HEALTH Randomised, Controlled Trial. Mol Nutr Food Res. 2021 05; 65(10):e2001178.
Effect of Mastiha supplementation on NAFLD: The MAST4HEALTH Randomised, Controlled Trial.
Kanoni S, Kumar S, Amerikanou C, Kurth MJ, Stathopoulou MG, Bourgeois S, Masson C, Kannt A, Cesarini L, Kontoe MS, Milanovic M, Roig FJ, Beribaka M, Campolo J, Jiménez-Hernández N, Miloševic N, Llorens C, Smyrnioudis I, Francino MP, Milic N, Kaliora AC, Trivella MG, Ruddock MW, Medic-Stojanoska M, Gastaldelli A, Lamont J, Deloukas P, Dedoussis GV, Visvikis-Siest S
Nutrigenetic Interactions Might Modulate the Antioxidant and Anti-Inflammatory Status in Mastiha-Supplemented Patients With NAFLD. Front Immunol. 2021; 12:683028.
Nutrigenetic Interactions Might Modulate the Antioxidant and Anti-Inflammatory Status in Mastiha-Supplemented Patients With NAFLD.
Visvikis-Siest S, Stathopoulou MG, Sunder-Plassmann R, Alizadeh BZ, Barouki R, Chatzaki E, Dagher G, Dedoussis G, Deloukas P, Haliassos A, Hiegel BB, Manolopoulos V, Masson C, Paré G, Paulmichl M, Petrelis AM, Sipeky C, Süsleyici B, Weryha G, Chenchik A, Diehl P, Everts RE, Haushofer A, Lamont J, Mercado R, Meyer H, Munoz-Galeano H, Murray H, Nhat F, Nofziger C, Schnitzel W, Kanoni S
The 10th Santorini conference: Systems medicine, personalised health and therapy. "The odyssey from hope to practice: Patient first. Keep Ithaca always in your mind", Santorini, Greece, 23-26 May 2022. Front Genet. 2023; 14:1171131.
The 10th Santorini conference: Systems medicine, personalised health and therapy. "The odyssey from hope to practice: Patient first. Keep Ithaca always in your mind", Santorini, Greece, 23-26 May 2022.
Evidence-based management of gastrointestinal diseases. Gastroenterol Rep (Oxf). 2015 Feb; 3(1):1-2.
Evidence-based management of gastrointestinal diseases.
Clostridium difficile infection. N Engl J Med. 2015 Apr 16; 372(16):1539-48.
Clostridium difficile Infection. N Engl J Med. 2015 07 16; 373(3):287-8.
Kim DH, Hwang JS, Lee IH, Nam ST, Hong J, Zhang P, Lu LF, Lee J, Seok H, Pothoulakis C, Lamont JT, Kim H
The Insect Peptide CopA3 Increases Colonic Epithelial Cell Proliferation and Mucosal Barrier Function to Prevent Inflammatory Responses in the Gut. J Biol Chem. 2016 Feb 12; 291(7):3209-23.
The Insect Peptide CopA3 Increases Colonic Epithelial Cell Proliferation and Mucosal Barrier Function to Prevent Inflammatory Responses in the Gut.
Cholesterol gallstone formation. 2. Pathobiology and pathomechanics. Prog Liver Dis. 1992; 10:165-91.
Cholesterol gallstone formation. 2. Pathobiology and pathomechanics.
Cholesterol gallstone formation. 1. Physical-chemistry of bile and biliary lipid secretion. Prog Liver Dis. 1992; 10:139-63.
Cholesterol gallstone formation. 1. Physical-chemistry of bile and biliary lipid secretion.
Larson RG, Turner BS, Bhaskar KR, LaMont JT, Rothschild MF
Rapid communication: BamHI restriction fragment length polymorphism detected with a pig gastric mucin (MUC5AC) probe. J Anim Sci. 1996 Jun; 74(6):1443.
Rapid communication: BamHI restriction fragment length polymorphism detected with a pig gastric mucin (MUC5AC) probe.
Grübel P, Bhaskar KR, Cave DR, Garik P, Stanley HE, Lamont JT
Interaction of an aluminum-magnesium containing antacid and gastric mucus: possible contribution to the cytoprotective function of antacids. Aliment Pharmacol Ther. 1997 Feb; 11(1):139-45.
Interaction of an aluminum-magnesium containing antacid and gastric mucus: possible contribution to the cytoprotective function of antacids.
Kelly CP, Pothoulakis C, Vavva F, Castagliuolo I, Bostwick EF, O'Keane JC, Keates S, LaMont JT
Anti-Clostridium difficile bovine immunoglobulin concentrate inhibits cytotoxicity and enterotoxicity of C. difficile toxins. Antimicrob Agents Chemother. 1996 Feb; 40(2):373-9.
Anti-Clostridium difficile bovine immunoglobulin concentrate inhibits cytotoxicity and enterotoxicity of C. difficile toxins.
Kelly CP, Chetham S, Keates S, Bostwick EF, Roush AM, Castagliuolo I, LaMont JT, Pothoulakis C
Survival of anti-Clostridium difficile bovine immunoglobulin concentrate in the human gastrointestinal tract. Antimicrob Agents Chemother. 1997 Feb; 41(2):236-41.
Survival of anti-Clostridium difficile bovine immunoglobulin concentrate in the human gastrointestinal tract.
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Effect of chondroitinase ABC on purulent sputum from cystic fibrosis and other patients.
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FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Choline, an essential nutrient for humans. FASEB J. 1991 Apr; 5(7):2093-8.
Choline, an essential nutrient for humans.
Castagliuolo I, LaMont JT, Nikulasson ST, Pothoulakis C
Saccharomyces boulardii protease inhibits Clostridium difficile toxin A effects in the rat ileum. Infect Immun. 1996 Dec; 64(12):5225-32.
Saccharomyces boulardii protease inhibits Clostridium difficile toxin A effects in the rat ileum.
Rational approach to iron-deficiency anaemia in premenopausal women. Lancet. 1998 Dec 19-26; 352(9145):1953-4.
Rational approach to iron-deficiency anaemia in premenopausal women.
Morrin MM, Farrell RJ, Kruskal JB, LaMont JT
Virtual colonoscopy: a kinder, gentler colorectal cancer screening test? Lancet. 1999 Sep 25; 354(9184):1048-9.
Virtual colonoscopy: a kinder, gentler colorectal cancer screening test?
Riegler M, Sedivy R, Sogukoglu T, Castagliuolo I, Pothoulakis C, Cosentini E, Bischof G, Hamilton G, Teleky B, Feil W, Lamont JT, Wenzl E
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Epidermal growth factor attenuates Clostridium difficile toxin A- and B-induced damage of human colonic mucosa.
Salcedo J, Keates S, Pothoulakis C, Warny M, Castagliuolo I, LaMont JT, Kelly CP
Intravenous immunoglobulin therapy for severe Clostridium difficile colitis. Gut. 1997 Sep; 41(3):366-70.
Intravenous immunoglobulin therapy for severe Clostridium difficile colitis.
Miller PD, Pothoulakis C, Baeker TR, LaMont JT, Rothstein TL
Macrophage-dependent stimulation of T cell-depleted spleen cells by Clostridium difficile toxin A and calcium ionophore. Cell Immunol. 1990 Mar; 126(1):155-63.
Macrophage-dependent stimulation of T cell-depleted spleen cells by Clostridium difficile toxin A and calcium ionophore.
Moore R, Pothoulakis C, LaMont JT, Carlson S, Madara JL
C. difficile toxin A increases intestinal permeability and induces Cl- secretion. Am J Physiol. 1990 Aug; 259(2 Pt 1):G165-72.
C. difficile toxin A increases intestinal permeability and induces Cl- secretion.
Protein kinase C signaling regulates ZO-1 translocation and increased paracellular flux of T84 colonocytes exposed to Clostridium difficile toxin A. J Biol Chem. 2002 Feb 08; 277(6):4247-54.
Protein kinase C signaling regulates ZO-1 translocation and increased paracellular flux of T84 colonocytes exposed to Clostridium difficile toxin A.
Non-antibiotic therapy for Clostridium difficile infection. Curr Opin Infect Dis. 2000 Jun; 13(3):215-219.
Non-antibiotic therapy for Clostridium difficile infection.
Espenschied J, Lamont J, Longmate J, Pendas S, Wang Z, Diamond DJ, Ellenhorn JD
Journal of immunology (Baltimore, Md. : 1950)
CTLA-4 blockade enhances the therapeutic effect of an attenuated poxvirus vaccine targeting p53 in an established murine tumor model. J Immunol. 2003 Mar 15; 170(6):3401-7.
CTLA-4 blockade enhances the therapeutic effect of an attenuated poxvirus vaccine targeting p53 in an established murine tumor model.
Stimulation of colonic glycoprotein synthesis by dibutyryl cyclic AMP and theophylline. Gastroenterology. 1977 Jan; 72(1):82-6.
Stimulation of colonic glycoprotein synthesis by dibutyryl cyclic AMP and theophylline.
Castagliuolo I, Lamont JT, Qiu B, Fleming SM, Bhaskar KR, Nikulasson ST, Kornetsky C, Pothoulakis C
Acute stress causes mucin release from rat colon: role of corticotropin releasing factor and mast cells. Am J Physiol. 1996 Nov; 271(5 Pt 1):G884-92.
Acute stress causes mucin release from rat colon: role of corticotropin releasing factor and mast cells.
Microbial factors in inflammatory bowel disease. Gastroenterol Clin North Am. 2002 Mar; 31(1):41-62.
Microbial factors in inflammatory bowel disease.
Endangered species. Gastroenterology. 1999 Jul; 117(1):5.
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Cysteine-rich regions of pig gastric mucin contain von willebrand factor and cystine knot domains at the carboxyl terminal(1). Biochim Biophys Acta. 1999 Oct 06; 1447(1):77-92.
Cysteine-rich regions of pig gastric mucin contain von willebrand factor and cystine knot domains at the carboxyl terminal(1).
Agarwal B, Halmos B, Feoktistov AS, Protiva P, Ramey WG, Chen M, Pothoulakis C, Lamont JT, Holt PR
Mechanism of lovastatin-induced apoptosis in intestinal epithelial cells. Carcinogenesis. 2002 Mar; 23(3):521-8.
Mechanism of lovastatin-induced apoptosis in intestinal epithelial cells.
Warny M, Fatimi A, Bostwick EF, Laine DC, Lebel F, LaMont JT, Pothoulakis C, Kelly CP
Bovine immunoglobulin concentrate-clostridium difficile retains C difficile toxin neutralising activity after passage through the human stomach and small intestine. Gut. 1999 Feb; 44(2):212-7.
Bovine immunoglobulin concentrate-clostridium difficile retains C difficile toxin neutralising activity after passage through the human stomach and small intestine.
Annals of the New York Academy of Sciences
Mucus: the front line of intestinal mucosal defense. Ann N Y Acad Sci. 1992; 664:190-201.
Mucus: the front line of intestinal mucosal defense.
The renaissance of probiotics and prebiotics. Gastroenterology. 2000 Aug; 119(2):291.
The renaissance of probiotics and prebiotics.
Nam HJ, Kang JK, Kim SK, Ahn KJ, Seok H, Park SJ, Chang JS, Pothoulakis C, Lamont JT, Kim H
Clostridium difficile toxin A decreases acetylation of tubulin, leading to microtubule depolymerization through activation of histone deacetylase 6, and this mediates acute inflammation. J Biol Chem. 2010 Oct 22; 285(43):32888-32896.
Clostridium difficile toxin A decreases acetylation of tubulin, leading to microtubule depolymerization through activation of histone deacetylase 6, and this mediates acute inflammation.
Liu TS, Musch MW, Sugi K, Walsh-Reitz MM, Ropeleski MJ, Hendrickson BA, Pothoulakis C, Lamont JT, Chang EB
American journal of physiology. Cell physiology
Protective role of HSP72 against Clostridium difficile toxin A-induced intestinal epithelial cell dysfunction. Am J Physiol Cell Physiol. 2003 Apr; 284(4):C1073-82.
Protective role of HSP72 against Clostridium difficile toxin A-induced intestinal epithelial cell dysfunction.
Bhaskar KR, Gong DH, Bansil R, Pajevic S, Hamilton JA, Turner BS, LaMont JT
Profound increase in viscosity and aggregation of pig gastric mucin at low pH. Am J Physiol. 1991 Nov; 261(5 Pt 1):G827-32.
Profound increase in viscosity and aggregation of pig gastric mucin at low pH.
Gong DH, Turner B, Bhaskar KR, Lamont JT
Lipid binding to gastric mucin: protective effect against oxygen radicals. Am J Physiol. 1990 Oct; 259(4 Pt 1):G681-6.
Lipid binding to gastric mucin: protective effect against oxygen radicals.
Kelly CP, Pothoulakis C, Orellana J, LaMont JT
Human colonic aspirates containing immunoglobulin A antibody to Clostridium difficile toxin A inhibit toxin A-receptor binding. Gastroenterology. 1992 Jan; 102(1):35-40.
Human colonic aspirates containing immunoglobulin A antibody to Clostridium difficile toxin A inhibit toxin A-receptor binding.
Qamar A, Aboudola S, Warny M, Michetti P, Pothoulakis C, LaMont JT, Kelly CP
Saccharomyces boulardii stimulates intestinal immunoglobulin A immune response to Clostridium difficile toxin A in mice. Infect Immun. 2001 Apr; 69(4):2762-5.
Saccharomyces boulardii stimulates intestinal immunoglobulin A immune response to Clostridium difficile toxin A in mice.
Pothoulakis C, Galili U, Castagliuolo I, Kelly CP, Nikulasson S, Dudeja PK, Brasitus TA, LaMont JT
A human antibody binds to alpha-galactose receptors and mimics the effects of Clostridium difficile toxin A in rat colon. Gastroenterology. 1996 Jun; 110(6):1704-12.
A human antibody binds to alpha-galactose receptors and mimics the effects of Clostridium difficile toxin A in rat colon.
Learning from the mistakes of Malthus: GI and manpower planning. Gastroenterology. 1997 Feb; 112(2):325.
Learning from the mistakes of Malthus: GI and manpower planning.
Warny M, Keates AC, Keates S, Castagliuolo I, Zacks JK, Aboudola S, Qamar A, Pothoulakis C, LaMont JT, Kelly CP
p38 MAP kinase activation by Clostridium difficile toxin A mediates monocyte necrosis, IL-8 production, and enteritis. J Clin Invest. 2000 Apr; 105(8):1147-56.
p38 MAP kinase activation by Clostridium difficile toxin A mediates monocyte necrosis, IL-8 production, and enteritis.
Is successful triage of patients with upper-gastrointestinal bleeding possible without endoscopy? Lancet. 2000 Oct 14; 356(9238):1289-90.
Is successful triage of patients with upper-gastrointestinal bleeding possible without endoscopy?
Transactions of the American Clinical and Climatological Association
Theodore E. Woodward Award. How bacterial enterotoxins work: insights from in vivo studies. Trans Am Clin Climatol Assoc. 2002; 113:167-80; discussion 180-1.
Theodore E. Woodward Award. How bacterial enterotoxins work: insights from in vivo studies.
Current topics in microbiology and immunology
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Pathogenesis and clinical manifestations of Clostridium difficile diarrhea and colitis.
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Effect of purified Clostridium difficile toxins on intestinal smooth muscle. II. Toxin B.
Berzin TM, Blanco PG, Lamont JT, Sawhney MS
Persistent psychological or physical symptoms following endoscopic procedures: an unrecognized post-endoscopy adverse event. Dig Dis Sci. 2010 Oct; 55(10):2869-73.
Persistent psychological or physical symptoms following endoscopic procedures: an unrecognized post-endoscopy adverse event.
Pothoulakis C, LaMont JT, Eglow R, Gao N, Rubins JB, Theoharides TC, Dickey BF
Characterization of rabbit ileal receptors for Clostridium difficile toxin A. Evidence for a receptor-coupled G protein. J Clin Invest. 1991 Jul; 88(1):119-25.
Characterization of rabbit ileal receptors for Clostridium difficile toxin A. Evidence for a receptor-coupled G protein.
Kim H, Kokkotou E, Na X, Rhee SH, Moyer MP, Pothoulakis C, Lamont JT
Clostridium difficile toxin A-induced colonocyte apoptosis involves p53-dependent p21(WAF1/CIP1) induction via p38 mitogen-activated protein kinase. Gastroenterology. 2005 Dec; 129(6):1875-88.
Clostridium difficile toxin A-induced colonocyte apoptosis involves p53-dependent p21(WAF1/CIP1) induction via p38 mitogen-activated protein kinase.
Riegler M, Lotz M, Sears C, Pothoulakis C, Castagliuolo I, Wang CC, Sedivy R, Sogukoglu T, Cosentini E, Bischof G, Feil W, Teleky B, Hamilton G, LaMont JT, Wenzl E
Bacteroides fragilis toxin 2 damages human colonic mucosa in vitro. Gut. 1999 Apr; 44(4):504-10.
Bacteroides fragilis toxin 2 damages human colonic mucosa in vitro.
Hydrophobic binding properties of bovine gallbladder mucin. J Biol Chem. 1984 Oct 10; 259(19):12170-7.
Hydrophobic binding properties of bovine gallbladder mucin.
Diarrhea we can treat: antibiotic-associated colitis. Compr Ther. 1982 Aug; 8(8):36-43.
Diarrhea we can treat: antibiotic-associated colitis.
Mucin biophysics. Annu Rev Physiol. 1995; 57:635-57.
Na X, Kim H, Moyer MP, Pothoulakis C, LaMont JT
gp96 is a human colonocyte plasma membrane binding protein for Clostridium difficile toxin A. Infect Immun. 2008 Jul; 76(7):2862-71.
gp96 is a human colonocyte plasma membrane binding protein for Clostridium difficile toxin A.
Wands JR, LaMont JT, Mann E, Isselbacher KJ
Arthritis associated with intestinal-bypass procedure for morbid obesity. Complement activation and characterization of circulating cryoproteins. N Engl J Med. 1976 Jan 15; 294(3):121-4.
Arthritis associated with intestinal-bypass procedure for morbid obesity. Complement activation and characterization of circulating cryoproteins.
Bousvaros A, Stevens AC, Strom TB, Murphy J, Lamont JT
Interleukin-2 fusion protein (DAB389IL-2) selectively targets activated human peripheral blood and lamina propria lymphocytes. Dig Dis Sci. 1997 Jul; 42(7):1542-8.
Interleukin-2 fusion protein (DAB389IL-2) selectively targets activated human peripheral blood and lamina propria lymphocytes.
Cao X, Bansil R, Bhaskar KR, Turner BS, LaMont JT, Niu N, Afdhal NH
pH-dependent conformational change of gastric mucin leads to sol-gel transition. Biophys J. 1999 Mar; 76(3):1250-8.
pH-dependent conformational change of gastric mucin leads to sol-gel transition.
Treatment of Clostridium difficile-associated disease. Gastroenterology. 2009 May; 136(6):1899-912.
Treatment of Clostridium difficile-associated disease.
American journal of physiology. Gastrointestinal and liver physiology
Microbes and microbial toxins: paradigms for microbial-mucosal interactions II. The integrated response of the intestine to Clostridium difficile toxins. Am J Physiol Gastrointest Liver Physiol. 2001 Feb; 280(2):G178-83.
Microbes and microbial toxins: paradigms for microbial-mucosal interactions II. The integrated response of the intestine to Clostridium difficile toxins.
Colorectal cancer. Risk factors and screening strategies. Arch Intern Med. 1984 Sep; 144(9):1819-23.
Colorectal cancer. Risk factors and screening strategies.
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Purification and composition of colonic epithelial mucin.
Recurrent pseudo-Crohn's disease. Dig Dis Sci. 1995 Sep; 40(9):1922-4.
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Passing the torch: a look back at our editorship. Gastroenterology. 1996 May; 110(5):1336-8.
Passing the torch: a look back at our editorship.
Gastrointestinal problems in the chronically critically ill patient. Clin Chest Med. 2001 Mar; 22(1):135-47.
Gastrointestinal problems in the chronically critically ill patient.
Na X, Zhao D, Koon HW, Kim H, Husmark J, Moyer MP, Pothoulakis C, LaMont JT
Clostridium difficile toxin B activates the EGF receptor and the ERK/MAP kinase pathway in human colonocytes. Gastroenterology. 2005 Apr; 128(4):1002-11.
Clostridium difficile toxin B activates the EGF receptor and the ERK/MAP kinase pathway in human colonocytes.
Journal of pediatric gastroenterology and nutrition
Asymptomatic colonization by Clostridium difficile in infants: implications for disease in later life. J Pediatr Gastroenterol Nutr. 2010 Jul; 51(1):2-7.
Asymptomatic colonization by Clostridium difficile in infants: implications for disease in later life.
Castagliuolo I, Kelly CP, Qiu BS, Nikulasson ST, LaMont JT, Pothoulakis C
IL-11 inhibits Clostridium difficile toxin A enterotoxicity in rat ileum. Am J Physiol. 1997 Aug; 273(2 Pt 1):G333-41.
IL-11 inhibits Clostridium difficile toxin A enterotoxicity in rat ileum.
Grisham MB, Von Ritter C, Smith BF, Lamont JT, Granger DN
Interaction between oxygen radicals and gastric mucin. Am J Physiol. 1987 Jul; 253(1 Pt 1):G93-6.
Interaction between oxygen radicals and gastric mucin.
Cholestasis: medical or surgical? Hosp Pract (Off Ed). 1985 Feb 15; 20(2):82A, 82B, 82C passim.
Role of clostridial toxin in the pathogenesis of clindamycin colitis in rabbits. Gastroenterology. 1979 Feb; 76(2):356-61.
Role of clostridial toxin in the pathogenesis of clindamycin colitis in rabbits.
Viral hepatitis; how to reduce its threat to the patient and others (including you). Nursing. 1976 May; 6(5):31-8.
Viral hepatitis; how to reduce its threat to the patient and others (including you).
Pothoulakis C, Castagliuolo I, LaMont JT
Journal of gastroenterology and hepatology
Diagnostic tests for Clostridium difficile diarrhoea and colitis: past, present and future. J Gastroenterol Hepatol. 1993 Jul-Aug; 8(4):311-2.
Diagnostic tests for Clostridium difficile diarrhoea and colitis: past, present and future.
News in physiological sciences : an international journal of physiology produced jointly by the International Union of Physiological Sciences and the American Physiological Society
Nerves and Intestinal Mast Cells Modulate Responses to Enterotoxins. News Physiol Sci. 1998 Apr; 13:58-63.
Nerves and Intestinal Mast Cells Modulate Responses to Enterotoxins.
Hecht G, Koutsouris A, Pothoulakis C, LaMont JT, Madara JL
Clostridium difficile toxin B disrupts the barrier function of T84 monolayers. Gastroenterology. 1992 Feb; 102(2):416-23.
Clostridium difficile toxin B disrupts the barrier function of T84 monolayers.
Recurrent clostridium difficile. Gastroenterology. 2006 Apr; 130(4):1311-6.
Pothoulakis C, Sullivan R, Melnick DA, Triadafilopoulos G, Gadenne AS, Meshulam T, LaMont JT
Clostridium difficile toxin A stimulates intracellular calcium release and chemotactic response in human granulocytes. J Clin Invest. 1988 Jun; 81(6):1741-5.
Clostridium difficile toxin A stimulates intracellular calcium release and chemotactic response in human granulocytes.
Kim H, Rhee SH, Kokkotou E, Na X, Savidge T, Moyer MP, Pothoulakis C, LaMont JT
Clostridium difficile toxin A regulates inducible cyclooxygenase-2 and prostaglandin E2 synthesis in colonocytes via reactive oxygen species and activation of p38 MAPK. J Biol Chem. 2005 Jun 03; 280(22):21237-45.
Clostridium difficile toxin A regulates inducible cyclooxygenase-2 and prostaglandin E2 synthesis in colonocytes via reactive oxygen species and activation of p38 MAPK.
Castagliuolo I, LaMont JT, Letourneau R, Kelly C, O'Keane JC, Jaffer A, Theoharides TC, Pothoulakis C
Neuronal involvement in the intestinal effects of Clostridium difficile toxin A and Vibrio cholerae enterotoxin in rat ileum. Gastroenterology. 1994 Sep; 107(3):657-65.
Neuronal involvement in the intestinal effects of Clostridium difficile toxin A and Vibrio cholerae enterotoxin in rat ileum.
Li Y, Sun X, LaMont JT, Pardee AB, Li CJ
Selective killing of cancer cells by beta -lapachone: direct checkpoint activation as a strategy against cancer. Proc Natl Acad Sci U S A. 2003 Mar 04; 100(5):2674-8.
Selective killing of cancer cells by beta -lapachone: direct checkpoint activation as a strategy against cancer.
Cell-surface glycosyltransferases in cultured fibroblasts: increased activity and release during serum stimulation of growth. Proc Natl Acad Sci U S A. 1977 Mar; 74(3):1086-90.
Cell-surface glycosyltransferases in cultured fibroblasts: increased activity and release during serum stimulation of growth.
Smith BF, Peetermans JA, Tanaka T, LaMont JT
Subunit interactions and physical properties of bovine gallbladder mucin. Gastroenterology. 1989 Jul; 97(1):179-87.
Subunit interactions and physical properties of bovine gallbladder mucin.
Experimental colon cancer. Gastroenterology. 1978 Dec; 75(6):1157-69.
The American journal of gastroenterology
Editorial: not so nosocomial anymore: the growing threat of community-acquired Clostridium difficile. Am J Gastroenterol. 2012 Jan; 107(1):96-8.
Editorial: not so nosocomial anymore: the growing threat of community-acquired Clostridium difficile.
Kim H, Rhee SH, Pothoulakis C, Lamont JT
Inflammation and apoptosis in Clostridium difficile enteritis is mediated by PGE2 up-regulation of Fas ligand. Gastroenterology. 2007 Sep; 133(3):875-86.
Inflammation and apoptosis in Clostridium difficile enteritis is mediated by PGE2 up-regulation of Fas ligand.
Mono-, di- and trimethylamine in human gastric fluid: potential substrates for nitrosodimethylamine formation. Carcinogenesis. 1988 Jan; 9(1):179-81.
Mono-, di- and trimethylamine in human gastric fluid: potential substrates for nitrosodimethylamine formation.
Popp JW, Harrist TJ, Dienstag JL, Bhan AK, Wands JR, LaMont JT, Mihm MC
Cutaneous vasculitis associated with acute and chronic hepatitis. Arch Intern Med. 1981 Apr; 141(5):623-9.
Cutaneous vasculitis associated with acute and chronic hepatitis.
Kurose I, Pothoulakis C, LaMont JT, Anderson DC, Paulson JC, Miyasaka M, Wolf R, Granger DN
Clostridium difficile toxin A-induced microvascular dysfunction. Role of histamine. J Clin Invest. 1994 Nov; 94(5):1919-26.
Clostridium difficile toxin A-induced microvascular dysfunction. Role of histamine.
Pothoulakis C, Karmeli F, Kelly CP, Eliakim R, Joshi MA, O'Keane CJ, Castagliuolo I, LaMont JT, Rachmilewitz D
Ketotifen inhibits Clostridium difficile toxin A-induced enteritis in rat ileum. Gastroenterology. 1993 Sep; 105(3):701-7.
Ketotifen inhibits Clostridium difficile toxin A-induced enteritis in rat ileum.
Toxic megacolon in ulcerative colitis. Early diagnosis and management. Hosp Pract (Off Ed). 1986 Sep 15; 21(9):102A-102D, 102H, 102K-102M passim.
Toxic megacolon in ulcerative colitis. Early diagnosis and management.
Dillon ST, Rubin EJ, Yakubovich M, Pothoulakis C, LaMont JT, Feig LA, Gilbert RJ
Involvement of Ras-related Rho proteins in the mechanisms of action of Clostridium difficile toxin A and toxin B. Infect Immun. 1995 Apr; 63(4):1421-6.
Involvement of Ras-related Rho proteins in the mechanisms of action of Clostridium difficile toxin A and toxin B.
Postoperative jaundice. Semin Liver Dis. 1988 May; 8(2):183-90.
Cell surface glycosyltransferase activity in normal and neoplastic intestinal epithelium of the rat. Cancer Res. 1974 Dec; 34(12):3225-8.
Cell surface glycosyltransferase activity in normal and neoplastic intestinal epithelium of the rat.
Inactivation of Clostridium difficile cytotoxin by the neutrophil myeloperoxidase system. J Infect Dis. 1984 Feb; 149(2):215-9.
Inactivation of Clostridium difficile cytotoxin by the neutrophil myeloperoxidase system.
Linevsky JK, Pothoulakis C, Keates S, Warny M, Keates AC, Lamont JT, Kelly CP
IL-8 release and neutrophil activation by Clostridium difficile toxin-exposed human monocytes. Am J Physiol. 1997 12; 273(6):G1333-40.
IL-8 release and neutrophil activation by Clostridium difficile toxin-exposed human monocytes.
Castagliuolo I, Keates AC, Wang CC, Pasha A, Valenick L, Kelly CP, Nikulasson ST, LaMont JT, Pothoulakis C
Clostridium difficile toxin A stimulates macrophage-inflammatory protein-2 production in rat intestinal epithelial cells. J Immunol. 1998 Jun 15; 160(12):6039-45.
Clostridium difficile toxin A stimulates macrophage-inflammatory protein-2 production in rat intestinal epithelial cells.
Eglow R, Pothoulakis C, Itzkowitz S, Israel EJ, O'Keane CJ, Gong D, Gao N, Xu YL, Walker WA, LaMont JT
Diminished Clostridium difficile toxin A sensitivity in newborn rabbit ileum is associated with decreased toxin A receptor. J Clin Invest. 1992 Sep; 90(3):822-9.
Diminished Clostridium difficile toxin A sensitivity in newborn rabbit ileum is associated with decreased toxin A receptor.
Bhaskar KR, Garik P, Turner BS, Bradley JD, Bansil R, Stanley HE, LaMont JT
Viscous fingering of HCl through gastric mucin. Nature. 1992 Dec 03; 360(6403):458-61.
Viscous fingering of HCl through gastric mucin.
O'Leary DP, Murray FE, Turner BS, LaMont JT
Bile salts stimulate glycoprotein release by guinea pig gallbladder in vitro. Hepatology. 1991 May; 13(5):957-61.
Bile salts stimulate glycoprotein release by guinea pig gallbladder in vitro.
Castagliuolo I, Riegler MF, Valenick L, LaMont JT, Pothoulakis C
Saccharomyces boulardii protease inhibits the effects of Clostridium difficile toxins A and B in human colonic mucosa. Infect Immun. 1999 Jan; 67(1):302-7.
Saccharomyces boulardii protease inhibits the effects of Clostridium difficile toxins A and B in human colonic mucosa.
Therapeutic implications of Clostridium difficile toxin during relapse of chronic inflammatory bowel disease. Lancet. 1980 Feb 23; 1(8165):381-3.
Therapeutic implications of Clostridium difficile toxin during relapse of chronic inflammatory bowel disease.
LaMont JT, Ventola AS, Trotman BW, Soloway RD
Mucin glycoprotein content of human pigment gallstones. Hepatology. 1983 May-Jun; 3(3):377-82.
Mucin glycoprotein content of human pigment gallstones.
Unlocking the secrets of the porcelain vase. Gastroenterology. 2000 Nov; 119(5):1397-9.
Unlocking the secrets of the porcelain vase.
Role of gallbladder mucus hypersecretion in the evolution of cholesterol gallstones. J Clin Invest. 1981 Jun; 67(6):1712-23.
Role of gallbladder mucus hypersecretion in the evolution of cholesterol gallstones.
Cryptosporidiosis and public health. Hosp Pract (1995). 1997 Jul 15; 32(7):11, 15-6, 23.
Kelly CP, O'Keane JC, Orellana J, Schroy PC, Yang S, LaMont JT, Brady HR
Human colon cancer cells express ICAM-1 in vivo and support LFA-1-dependent lymphocyte adhesion in vitro. Am J Physiol. 1992 Dec; 263(6 Pt 1):G864-70.
Human colon cancer cells express ICAM-1 in vivo and support LFA-1-dependent lymphocyte adhesion in vitro.
Bhaskar KR, Turner BS, Grubman SA, Jefferson DM, LaMont JT
Dysregulation of proteoglycan production by intrahepatic biliary epithelial cells bearing defective (delta-f508) cystic fibrosis transmembrane conductance regulator. Hepatology. 1998 Jan; 27(1):7-14.
Dysregulation of proteoglycan production by intrahepatic biliary epithelial cells bearing defective (delta-f508) cystic fibrosis transmembrane conductance regulator.