Johnson RJ, Bakris GL, Borghi C, Chonchol MB, Feldman D, Lanaspa MA, Merriman TR, Moe OW, Mount DB, Sanchez Lozada LG, Stahl E, Weiner DE, Chertow GM
American journal of kidney diseases : the official journal of the National Kidney Foundation
Hyperuricemia, Acute and Chronic Kidney Disease, Hypertension, and Cardiovascular Disease: Report of a Scientific Workshop Organized by the National Kidney Foundation. Am J Kidney Dis. 2018 06; 71(6):851-865.
Hyperuricemia, Acute and Chronic Kidney Disease, Hypertension, and Cardiovascular Disease: Report of a Scientific Workshop Organized by the National Kidney Foundation.
Song L, Mercado A, Vázquez N, Xie Q, Desai R, George AL, Gamba G, Mount DB
Brain research. Molecular brain research
Molecular, functional, and genomic characterization of human KCC2, the neuronal K-Cl cotransporter. Brain Res Mol Brain Res. 2002 Jun 30; 103(1-2):91-105.
Molecular, functional, and genomic characterization of human KCC2, the neuronal K-Cl cotransporter.
Rheumatic diseases clinics of North America
Renal urate transport. Rheum Dis Clin North Am. 2006 May; 32(2):313-31, vi.
Mount DB, Delpire E, Gamba G, Hall AE, Poch E, Hoover RS, Hebert SC
The electroneutral cation-chloride cotransporters. J Exp Biol. 1998 Jul; 201(Pt 14):2091-102.
The electroneutral cation-chloride cotransporters.
Plata C, Mount DB, Rubio V, Hebert SC, Gamba G
Isoforms of the Na-K-2Cl cotransporter in murine TAL II. Functional characterization and activation by cAMP. Am J Physiol. 1999 03; 276(3):F359-66.
Isoforms of the Na-K-2Cl cotransporter in murine TAL II. Functional characterization and activation by cAMP.
Romero MF, Chang MH, Plata C, Zandi-Nejad K, Mercado A, Broumand V, Sussman CR, Mount DB
Physiology of electrogenic SLC26 paralogues. Novartis Found Symp. 2006; 273:126-38; discussion 138-47, 261-4.
Physiology of electrogenic SLC26 paralogues.
Belenky MA, Sollars PJ, Mount DB, Alper SL, Yarom Y, Pickard GE
Cell-type specific distribution of chloride transporters in the rat suprachiasmatic nucleus. Neuroscience. 2010 Feb 17; 165(4):1519-37.
Cell-type specific distribution of chloride transporters in the rat suprachiasmatic nucleus.
The brain in hyponatremia: both culprit and victim. Semin Nephrol. 2009 May; 29(3):196-215.
The brain in hyponatremia: both culprit and victim.
Chang MH, Plata C, Sindic A, Ranatunga WK, Chen AP, Zandi-Nejad K, Chan KW, Thompson J, Mount DB, Romero MF
Slc26a9 is inhibited by the R-region of the cystic fibrosis transmembrane conductance regulator via the STAS domain. J Biol Chem. 2009 Oct 09; 284(41):28306-28318.
Slc26a9 is inhibited by the R-region of the cystic fibrosis transmembrane conductance regulator via the STAS domain.
Mortality after hospitalization with mild, moderate, and severe hyponatremia. Am J Med. 2009 Sep; 122(9):857-65.
Mortality after hospitalization with mild, moderate, and severe hyponatremia.
Pflugers Archiv : European journal of physiology
Molecular physiology of cation-coupled Cl- cotransport: the SLC12 family. Pflugers Arch. 2004 Feb; 447(5):580-93.
Molecular physiology of cation-coupled Cl- cotransport: the SLC12 family.
Karadsheh MF, Byun N, Mount DB, Delpire E
Localization of the KCC4 potassium-chloride cotransporter in the nervous system. Neuroscience. 2004; 123(2):381-91.
Localization of the KCC4 potassium-chloride cotransporter in the nervous system.
Pathogenesis of gout. Ann Intern Med. 2005 Oct 04; 143(7):499-516.
Woo NS, Lu J, England R, McClellan R, Dufour S, Mount DB, Deutch AY, Lovinger DM, Delpire E
Hyperexcitability and epilepsy associated with disruption of the mouse neuronal-specific K-Cl cotransporter gene. Hippocampus. 2002; 12(2):258-68.
Hyperexcitability and epilepsy associated with disruption of the mouse neuronal-specific K-Cl cotransporter gene.
Pan D, Kalfa TA, Wang D, Risinger M, Crable S, Ottlinger A, Chandra S, Mount DB, Hübner CA, Franco RS, Joiner CH
K-Cl cotransporter gene expression during human and murine erythroid differentiation. J Biol Chem. 2011 Sep 02; 286(35):30492-30503.
K-Cl cotransporter gene expression during human and murine erythroid differentiation.
Mercado A, Broumand V, Zandi-Nejad K, Enck AH, Mount DB
A C-terminal domain in KCC2 confers constitutive K+-Cl- cotransport. J Biol Chem. 2006 Jan 13; 281(2):1016-26.
A C-terminal domain in KCC2 confers constitutive K+-Cl- cotransport.
Fraga S, Luo Y, Jose P, Zandi-Nejad K, Mount DB, Soares-da-Silva P
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology
Dopamine D1-like receptor-mediated inhibition of Cl/HCO3- exchanger activity in rat intestinal epithelial IEC-6 cells is regulated by G protein-coupled receptor kinase 6 (GRK 6). Cell Physiol Biochem. 2006; 18(6):347-60.
Dopamine D1-like receptor-mediated inhibition of Cl/HCO3- exchanger activity in rat intestinal epithelial IEC-6 cells is regulated by G protein-coupled receptor kinase 6 (GRK 6).
Hyponatremia: case vignettes. Semin Nephrol. 2009 May; 29(3):300-17.
Role of T3 in thermogenic and trophic responses of brown adipose tissue to cold. Am J Physiol. 1989 Jul; 257(1 Pt 1):E81-7.
Role of T3 in thermogenic and trophic responses of brown adipose tissue to cold.
Current opinion in nephrology and hypertension
Collectrin and the kidney. Curr Opin Nephrol Hypertens. 2007 Sep; 16(5):427-9.
Renal physiology of SLC26 anion exchangers. Curr Opin Nephrol Hypertens. 2007 Sep; 16(5):484-90.
Renal physiology of SLC26 anion exchangers.
Jiao Y, Jin X, Yan J, Zhang C, Jiao F, Li X, Roe BA, Mount DB, Gu W
A deletion mutation in Slc12a6 is associated with neuromuscular disease in gaxp mice. Genomics. 2008 May; 91(5):407-14.
A deletion mutation in Slc12a6 is associated with neuromuscular disease in gaxp mice.
Hekmat-Scafe DS, Mercado A, Fajilan AA, Lee AW, Hsu R, Mount DB, Tanouye MA
Seizure sensitivity is ameliorated by targeted expression of K+-Cl- cotransporter function in the mushroom body of the Drosophila brain. Genetics. 2010 Jan; 184(1):171-83.
Seizure sensitivity is ameliorated by targeted expression of K+-Cl- cotransporter function in the mushroom body of the Drosophila brain.
Hyponatremia: introduction. Semin Nephrol. 2009 May; 29(3):175-7.
Hartmann AM, Wenz M, Mercado A, Störger C, Mount DB, Friauf E, Nothwang HG
Differences in the large extracellular loop between the K(+)-Cl(-) cotransporters KCC2 and KCC4. J Biol Chem. 2010 Jul 30; 285(31):23994-4002.
Differences in the large extracellular loop between the K(+)-Cl(-) cotransporters KCC2 and KCC4.
Taylor EN, Stampfer MJ, Mount DB, Curhan GC
Clinical journal of the American Society of Nephrology : CJASN
DASH-style diet and 24-hour urine composition. Clin J Am Soc Nephrol. 2010 Dec; 5(12):2315-22.
DASH-style diet and 24-hour urine composition.
INvestigations In Gout, Hyperuricemia, and comorbidiTies (INSIGHT) Center of Research Translation (CORT)
Molecular physiology and the four-component model of renal urate transport. Curr Opin Nephrol Hypertens. 2005 Sep; 14(5):460-3.
Molecular physiology and the four-component model of renal urate transport.
Mercado A, Vázquez N, Song L, Cortés R, Enck AH, Welch R, Delpire E, Gamba G, Mount DB
American journal of physiology. Renal physiology
NH2-terminal heterogeneity in the KCC3 K+-Cl- cotransporter. Am J Physiol Renal Physiol. 2005 Dec; 289(6):F1246-61.
NH2-terminal heterogeneity in the KCC3 K+-Cl- cotransporter.
Taylor EN, Mount DB, Forman JP, Curhan GC
Association of prevalent hypertension with 24-hour urinary excretion of calcium, citrate, and other factors. Am J Kidney Dis. 2006 May; 47(5):780-9.
Association of prevalent hypertension with 24-hour urinary excretion of calcium, citrate, and other factors.
Hardness anisotropy of acetaminophen crystals. Pharm Res. 1994 May; 11(5):616-23.
Hardness anisotropy of acetaminophen crystals.
Attmane-Elakeb A, Mount DB, Sibella V, Vernimmen C, Hebert SC, Bichara M
Stimulation by in vivo and in vitro metabolic acidosis of expression of rBSC-1, the Na+-K+(NH4+)-2Cl- cotransporter of the rat medullary thick ascending limb. J Biol Chem. 1998 Dec 11; 273(50):33681-91.
Stimulation by in vivo and in vitro metabolic acidosis of expression of rBSC-1, the Na+-K+(NH4+)-2Cl- cotransporter of the rat medullary thick ascending limb.
Mercado A, de los Heros P, Vázquez N, Meade P, Mount DB, Gamba G
American journal of physiology. Cell physiology
Functional and molecular characterization of the K-Cl cotransporter of Xenopus laevis oocytes. Am J Physiol Cell Physiol. 2001 Aug; 281(2):C670-80.
Functional and molecular characterization of the K-Cl cotransporter of Xenopus laevis oocytes.
Xie Q, Welch R, Mercado A, Romero MF, Mount DB
Molecular characterization of the murine Slc26a6 anion exchanger: functional comparison with Slc26a1. Am J Physiol Renal Physiol. 2002 Oct; 283(4):F826-38.
Molecular characterization of the murine Slc26a6 anion exchanger: functional comparison with Slc26a1.
Jenkins ME, Harlow GR, Liu Z, Shotwell MA, Ma J, Mount DW
Radiation-sensitive mutants of Arabidopsis thaliana. Genetics. 1995 Jun; 140(2):725-32.
Radiation-sensitive mutants of Arabidopsis thaliana.
Mendu ML, Ahmed S, Maron JK, Rao SK, Chaguturu SK, May MF, Mutter WP, Burdge KA, Steele DJR, Mount DB, Waikar SS, Weilburg JB, Sequist TD
Development of an electronic health record-based chronic kidney disease registry to promote population health management. BMC Nephrol. 2019 03 01; 20(1):72.
Development of an electronic health record-based chronic kidney disease registry to promote population health management.
Assistant Professor of Medicine, Part-time
Gupta S, McMahon GM, Motwani SS, Mount DB, Waikar SS
"Pleurex Desalination" in Malignancy-related Ascites: A Novel Mechanism of Hyponatremia. Am J Clin Oncol. 2020 01; 43(1):14-19.
"Pleurex Desalination" in Malignancy-related Ascites: A Novel Mechanism of Hyponatremia.
Interaction Between ITM2B and GLUT9 Links Urate Transport to Neurodegenerative Disorders. Front Physiol. 2019; 10:1323.
Interaction Between ITM2B and GLUT9 Links Urate Transport to Neurodegenerative Disorders.
Ware EB, Smith JA, Zhao W, Ganesvoort RT, Curhan GC, Pollak M, Mount DB, Turner ST, Chen G, Shah RJ, Kardia SLR, Lieske JC
Mayo Clinic proceedings. Innovations, quality & outcomes
Genome-wide Association Study of 24-Hour Urinary Excretion of Calcium, Magnesium, and Uric Acid. Mayo Clin Proc Innov Qual Outcomes. 2019 Dec; 3(4):448-460.
Genome-wide Association Study of 24-Hour Urinary Excretion of Calcium, Magnesium, and Uric Acid.
Boocock J, Leask M, Okada Y, Matsuo H, Kawamura Y, Shi Y, Li C, Mount DB, Mandal AK, Wang W, Cadzow M, Gosling AL, Major TJ, Horsfield JA, Choi HK, Fadason T, O'Sullivan J, Stahl EA, Merriman TR
Genomic dissection of 43 serum urate-associated loci provides multiple insights into molecular mechanisms of urate control. Hum Mol Genet. 2020 04 15; 29(6):923-943.
Genomic dissection of 43 serum urate-associated loci provides multiple insights into molecular mechanisms of urate control.
FitzGerald JD, Dalbeth N, Mikuls T, Brignardello-Petersen R, Guyatt G, Abeles AM, Gelber AC, Harrold LR, Khanna D, King C, Levy G, Libbey C, Mount D, Pillinger MH, Rosenthal A, Singh JA, Sims JE, Smith BJ, Wenger NS, Bae SS, Danve A, Khanna PP, Kim SC, Lenert A, Poon S, Qasim A, Sehra ST, Sharma TSK, Toprover M, Turgunbaev M, Zeng L, Zhang MA, Turner AS, Neogi T
2020 American College of Rheumatology Guideline for the Management of Gout. Arthritis Care Res (Hoboken). 2020 06; 72(6):744-760.
2020 American College of Rheumatology Guideline for the Management of Gout.
Arthritis & rheumatology (Hoboken, N.J.)
2020 American College of Rheumatology Guideline for the Management of Gout. Arthritis Rheumatol. 2020 06; 72(6):879-895.
Gupta S, Tio MC, Gutowski ED, Stecker MS, Verma A, Motwani SS, Mount DB, McMahon GM, Waikar SS
Incidence of Hyponatremia in Patients With Indwelling Peritoneal Catheters for Drainage of Malignant Ascites. JAMA Netw Open. 2020 10 01; 3(10):e2017859.
Incidence of Hyponatremia in Patients With Indwelling Peritoneal Catheters for Drainage of Malignant Ascites.
Bar R, Ben-Shalom E, Duvdevani M, Belostotsky R, Pollak MR, Mount DB, Bar-Gal R, Gnessin E, Tzur S, Curhan GC, Frishberg Y
Mutations in HOGA1 do Not Confer a Dominant Phenotype Manifesting as Kidney Stone Disease. J Urol. 2021 May; 205(5):1394-1399.
Mutations in HOGA1 do Not Confer a Dominant Phenotype Manifesting as Kidney Stone Disease.
Leask MP, Sumpter NA, Lupi AS, Vazquez AI, Reynolds RJ, Mount DB, Merriman TR
The Shared Genetic Basis of Hyperuricemia, Gout, and Kidney Function. Semin Nephrol. 2020 11; 40(6):586-599.
The Shared Genetic Basis of Hyperuricemia, Gout, and Kidney Function.
Introduction: Gout and the Kidney. Semin Nephrol. 2020 11; 40(6):533-534.
Molecular Pathophysiology of Uric Acid Homeostasis. Semin Nephrol. 2020 11; 40(6):535-549.
Molecular Pathophysiology of Uric Acid Homeostasis.
The Management of Gout in Renal Disease. Semin Nephrol. 2020 11; 40(6):600-613.
The Management of Gout in Renal Disease.
Efe O, García JDC, Mount DB, Sheridan AM
Refractory hypophosphatemia following ferric carboxymaltose administration. CEN Case Rep. 2021 11; 10(4):473-475.
Refractory hypophosphatemia following ferric carboxymaltose administration.
Wongboonsin J, Shah SI, Marty FM, Mount DB, Rennke HG, Murakami N
Osmotic Tubulopathy in a Patient With COVID-19 Treated With Remdesivir. Kidney Int Rep. 2021 Jul; 6(7):1987-1991.
Osmotic Tubulopathy in a Patient With COVID-19 Treated With Remdesivir.
McCormick N, O'Connor MJ, Yokose C, Merriman TR, Mount DB, Leong A, Choi HK
Assessing the Causal Relationships Between Insulin Resistance and Hyperuricemia and Gout Using Bidirectional Mendelian Randomization. Arthritis Rheumatol. 2021 11; 73(11):2096-2104.
Assessing the Causal Relationships Between Insulin Resistance and Hyperuricemia and Gout Using Bidirectional Mendelian Randomization.
Stamp LK, Farquhar H, Pisaniello HL, Vargas-Santos AB, Fisher M, Mount DB, Choi HK, Terkeltaub R, Hill CL, Gaffo AL
Management of gout in chronic kidney disease: a G-CAN Consensus Statement on the research priorities. Nat Rev Rheumatol. 2021 10; 17(10):633-641.
Management of gout in chronic kidney disease: a G-CAN Consensus Statement on the research priorities.
Mandal AK, Leask MP, Estiverne C, Choi HK, Merriman TR, Mount DB
Genetic and Physiological Effects of Insulin on Human Urate Homeostasis. Front Physiol. 2021; 12:713710.
Genetic and Physiological Effects of Insulin on Human Urate Homeostasis.
He Y, Xue X, Terkeltaub R, Dalbeth N, Merriman TR, Mount DB, Feng Z, Li X, Cui L, Liu Z, Xu Y, Chen Y, Li H, Ji A, Ji X, Wang X, Lu J, Li C
Association of acidic urine pH with impaired renal function in primary gout patients: a Chinese population-based cross-sectional study. Arthritis Res Ther. 2022 01 25; 24(1):32.
Association of acidic urine pH with impaired renal function in primary gout patients: a Chinese population-based cross-sectional study.
Portales-Castillo I, Mount DB, Nigwekar SU, Yu EW, Rennke HG, Gupta S
Zoledronic Acid-Associated Fanconi Syndrome in Patients With Cancer. Am J Kidney Dis. 2022 10; 80(4):555-559.
Zoledronic Acid-Associated Fanconi Syndrome in Patients With Cancer.
Zhuo M, Li J, Buckley LF, Tummalapalli SL, Mount DB, Steele DJR, Lucier DJ, Mendu ML
Prescribing Patterns of Sodium-Glucose Cotransporter-2 Inhibitors in Patients with CKD: A Cross-Sectional Registry Analysis. Kidney360. 2022 03 31; 3(3):455-464.
Prescribing Patterns of Sodium-Glucose Cotransporter-2 Inhibitors in Patients with CKD: A Cross-Sectional Registry Analysis.
Dalbeth N, Mihov B, Stewart A, Gamble GD, Merriman TR, Mount D, Reid IR, Stamp LK, Horne A
Effects of elevated serum urate on cardiometabolic and kidney function markers in a randomised clinical trial of inosine supplementation. Sci Rep. 2022 07 28; 12(1):12887.
Effects of elevated serum urate on cardiometabolic and kidney function markers in a randomised clinical trial of inosine supplementation.
Mandal AK, Leask MP, Sumpter NA, Choi HK, Merriman TR, Mount DB
Journal of the American Society of Nephrology : JASN
Genetic and Physiological Effects of Insulin-Like Growth Factor-1 (IGF-1) on Human Urate Homeostasis. J Am Soc Nephrol. 2023 03 01; 34(3):451-466.
Genetic and Physiological Effects of Insulin-Like Growth Factor-1 (IGF-1) on Human Urate Homeostasis.
Estiverne C, McMahon GM, Mount DB, Bianchi G, Pierce CD, Hakim H, Rennke HG, Czarnecki PG
Safety and Diagnostic Yield of Protocolized Percutaneous Kidney Biopsies in Mechanically Ventilated Patients With Acute Kidney Injury. Kidney Int Rep. 2023 Jun; 8(6):1255-1259.
Safety and Diagnostic Yield of Protocolized Percutaneous Kidney Biopsies in Mechanically Ventilated Patients With Acute Kidney Injury.
GROWTH OF HUMAN TUMOR CELLS IN SUSPENSION CULTURES. Cancer Res. 1963 Dec; 23:1735-41.
GROWTH OF HUMAN TUMOR CELLS IN SUSPENSION CULTURES.
Cohen LB, Kastenberg DM, Mount DB, Safdi AV
Current Issues in Optimal Bowel Preparation: Excerpts From a Roundtable Discussion Among Colon-Cleansing Experts. Gastroenterol Hepatol (N Y). 2009 Nov; 5(11 Suppl 19):3-11.
Current Issues in Optimal Bowel Preparation: Excerpts From a Roundtable Discussion Among Colon-Cleansing Experts.
Requiem for Urate Lowering in CKD? J Am Soc Nephrol. 2024 May 01; 35(5):525-527.
Mandal AK, Merriman TR, Choi HK, Mount DB
Caffeine Inhibits Both Basal and Insulin-Activated Urate Transport. Arthritis Rheumatol. 2024 Nov; 76(11):1658-1669.
Caffeine Inhibits Both Basal and Insulin-Activated Urate Transport.
Yet More Reassurance: Treat-to-Target With Allopurinol or Febuxostat is Safe and Effective in Lowering Serum Urate in People With CKD. Am J Kidney Dis. 2024 Nov; 84(5):529-531.
Yet More Reassurance: Treat-to-Target With Allopurinol or Febuxostat is Safe and Effective in Lowering Serum Urate in People With CKD.
Johnson RJ, Mandell BF, Schlesinger N, Mount DB, Botson JK, Abdellatif AA, Rhoades R, Singh JA
Controversies and practical management of patients with gout and chronic kidney disease. Kidney Int. 2024 10; 106(4):573-582.
Controversies and practical management of patients with gout and chronic kidney disease.
Toka HR, Yang J, Zera CA, Duffield JS, Pollak MR, Mount DB
Pregnancy-associated polyuria in familial renal glycosuria. Am J Kidney Dis. 2013 Dec; 62(6):1160-4.
Pregnancy-associated polyuria in familial renal glycosuria.
Weng TY, Chiu WT, Liu HS, Cheng HC, Shen MR, Mount DB, Chou CY
Glycosylation regulates the function and membrane localization of KCC4. Biochim Biophys Acta. 2013 May; 1833(5):1133-46.
Glycosylation regulates the function and membrane localization of KCC4.
The genetics of hyperuricaemia and gout. Nat Rev Rheumatol. 2012 Oct; 8(10):610-21.
The genetics of hyperuricaemia and gout.
Hui JY, Choi JW, Mount DB, Zhu Y, Zhang Y, Choi HK
The independent association between parathyroid hormone levels and hyperuricemia: a national population study. Arthritis Res Ther. 2012 Mar 10; 14(2):R56.
The independent association between parathyroid hormone levels and hyperuricemia: a national population study.
Egan JB, Thompson PA, Ashbeck EL, Conti DV, Duggan D, Hibler E, Jurutka PW, Leroy EC, Martínez ME, Mount D, Jacobs ET
Genetic polymorphisms in vitamin D receptor VDR/RXRA influence the likelihood of colon adenoma recurrence. Cancer Res. 2010 Feb 15; 70(4):1496-504.
Genetic polymorphisms in vitamin D receptor VDR/RXRA influence the likelihood of colon adenoma recurrence.
Lapinsky SE, Mount DB, Mackey D, Grossman RF
Management of acute respiratory failure due to pulmonary edema with nasal positive pressure support. Chest. 1994 Jan; 105(1):229-31.
Management of acute respiratory failure due to pulmonary edema with nasal positive pressure support.
Undetected Air Embolism During Hemodialysis from a Defective Central Venous Catheter Causing Intradialytic Cardiac Arrest: An Imaging Teaching Case. Kidney Med. 2024 Nov; 6(11):100915.
Undetected Air Embolism During Hemodialysis from a Defective Central Venous Catheter Causing Intradialytic Cardiac Arrest: An Imaging Teaching Case.
Toka HR, Genovese G, Mount DB, Pollak MR, Curhan GC
Frequency of rare allelic variation in candidate genes among individuals with low and high urinary calcium excretion. PLoS One. 2013; 8(8):e71885.
Frequency of rare allelic variation in candidate genes among individuals with low and high urinary calcium excretion.
Chowdhury RB, Ortega JL, Wells SL, Pirovano M, Kim R, Lima CS, Madken M, Khalid SB, El Fekih R, Alikhan FM, Peterkin AC, McMahon GM, Mount DB, Bonventre JV, Gupta S
Innovating Kidney Care in Patients with Cancer: Development of an Inpatient Onconephrology Service. Clin J Am Soc Nephrol. 2025 Oct 01; 20(10):1470-1473.
Innovating Kidney Care in Patients with Cancer: Development of an Inpatient Onconephrology Service.
Zandi-Nejad K, Takakura A, Jurewicz M, Chandraker AK, Offermanns S, Mount D, Abdi R
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
The role of HCA2 (GPR109A) in regulating macrophage function. FASEB J. 2013 Nov; 27(11):4366-74.
The role of HCA2 (GPR109A) in regulating macrophage function.
Melo Z, Cruz-Rangel S, Bautista R, Vázquez N, Castañeda-Bueno M, Mount DB, Pasantes-Morales H, Mercado A, Gamba G
Molecular evidence for a role for K(+)-Cl(-) cotransporters in the kidney. Am J Physiol Renal Physiol. 2013 Nov 15; 305(10):F1402-11.
Molecular evidence for a role for K(+)-Cl(-) cotransporters in the kidney.
Rossano AJ, Zhang L, Anderson JB, Holmes HL, Mandal AK, Decker JW, Mount DB, Romero MF
Ex vivo quantification of intracellular pH in Drosophila Malpighian tubule reveals basolateral HCO3-/oxalate exchange through a novel oxalate transporter "Neat". Front Physiol. 2025; 16:1468451.
Ex vivo quantification of intracellular pH in Drosophila Malpighian tubule reveals basolateral HCO3-/oxalate exchange through a novel oxalate transporter "Neat".
Mishima E, Inoue C, Saigusa D, Inoue R, Ito K, Suzuki Y, Jinno D, Tsukui Y, Akamatsu Y, Araki M, Araki K, Shimizu R, Shinke H, Suzuki T, Takeuchi Y, Shima H, Akiyama Y, Toyohara T, Suzuki C, Saiki Y, Tominaga T, Miyagi S, Kawagisihi N, Soga T, Ohkubo T, Yamamura K, Imai Y, Masuda S, Sabbisetti V, Ichimura T, Mount DB, Bonventre JV, Ito S, Tomioka Y, Itoh K, Abe T
Conformational change in transfer RNA is an early indicator of acute cellular damage. J Am Soc Nephrol. 2014 Oct; 25(10):2316-26.
Conformational change in transfer RNA is an early indicator of acute cellular damage.
Thick ascending limb of the loop of Henle. Clin J Am Soc Nephrol. 2014 Nov 07; 9(11):1974-86.
Thick ascending limb of the loop of Henle.
The molecular physiology of uric acid homeostasis. Annu Rev Physiol. 2015; 77:323-45.
The molecular physiology of uric acid homeostasis.
Best practice & research. Clinical endocrinology & metabolism
Diagnosis and treatment of hypernatremia. Best Pract Res Clin Endocrinol Metab. 2016 03; 30(2):189-203.
Diagnosis and treatment of hypernatremia.
Leaf DE, Cheng XS, Sanders JL, Mendu M, Schiff GD, Mount DB, Bazari H
An electronic alert to decrease Kayexalate ordering. Ren Fail. 2016 Nov; 38(10):1752-1754.
An electronic alert to decrease Kayexalate ordering.
REGULATION OF THE NA+/K+ 2C1 COTRANSPORTER PROTEIN
Molecular Physiology of Renal K-Cl Cotransporters
REGULATION OF NA/K/2CL COTRANSPORTER BY PHOSPHORYLATION
Gallek MJ, Skoch J, Ansay T, Behbahani M, Mount D, Manziello A, Witte M, Bernas M, Labiner DM, Weinand ME
Cortical gene expression: prognostic value for seizure outcome following temporal lobectomy and amygdalohippocampectomy. Neurogenetics. 2016 10; 17(4):211-218.
Cortical gene expression: prognostic value for seizure outcome following temporal lobectomy and amygdalohippocampectomy.
Sise ME, Wisocky J, Rosales IA, Chute D, Holmes JA, Corapi KM, Babitt JL, Tangren JS, Hashemi N, Lundquist AL, Williams WW, Mount DB, Andersson KL, Rennke HG, Smith RN, Colvin R, Thadhani RI, Chung RT
Lupus-like Immune Complex-mediated Glomerulonephritis in Patients with Hepatitis C Virus Infection Treated with Oral, Interferon-free, Direct-acting Antiviral Therapy. Kidney Int Rep. 2016 Sep; 1(3):135-143.
Lupus-like Immune Complex-mediated Glomerulonephritis in Patients with Hepatitis C Virus Infection Treated with Oral, Interferon-free, Direct-acting Antiviral Therapy.
Molecular mechanisms of NaCl cotransport. Annu Rev Physiol. 1996; 58:649-68.
Molecular mechanisms of NaCl cotransport.
López-Barradas A, González-Cid T, Vázquez N, Gavi-Maza M, Reyes-Camacho A, Velázquez-Villegas LA, Ramírez V, Zandi-Nejad K, Mount DB, Torres N, Tovar AR, Romero MF, Gamba G, Plata C
Insulin and SGK1 reduce the function of Na+/monocarboxylate transporter 1 (SMCT1/SLC5A8). Am J Physiol Cell Physiol. 2016 Nov 01; 311(5):C720-C734.
Insulin and SGK1 reduce the function of Na+/monocarboxylate transporter 1 (SMCT1/SLC5A8).
D'Agata EM, Mount DB, Thayer V, Schaffner W
Hospital-acquired infections among chronic hemodialysis patients. Am J Kidney Dis. 2000 Jun; 35(6):1083-8.
Hospital-acquired infections among chronic hemodialysis patients.
Genetics of gout. Curr Opin Rheumatol. 2010 Mar; 22(2):144-51.
Human and murine phenotypes associated with defects in cation-chloride cotransport. Annu Rev Physiol. 2002; 64:803-43.
Human and murine phenotypes associated with defects in cation-chloride cotransport.
Mandal AK, Mercado A, Foster A, Zandi-Nejad K, Mount DB
Uricosuric targets of tranilast. Pharmacol Res Perspect. 2017 Apr; 5(2):e00291.
Tanner C, Boocock J, Stahl EA, Dobbyn A, Mandal AK, Cadzow M, Phipps-Green AJ, Topless RK, Hindmarsh JH, Stamp LK, Dalbeth N, Choi HK, Mount DB, Merriman TR
Population-Specific Resequencing Associates the ATP-Binding Cassette Subfamily C Member 4 Gene With Gout in New Zealand Maori and Pacific Men. Arthritis Rheumatol. 2017 07; 69(7):1461-1469.
Population-Specific Resequencing Associates the ATP-Binding Cassette Subfamily C Member 4 Gene With Gout in New Zealand Maori and Pacific Men.
Localization of the K(+)-Cl(-) cotransporter, KCC3, in the central and peripheral nervous systems: expression in the choroid plexus, large neurons and white matter tracts. Neuroscience. 2001; 103(2):481-91.
Localization of the K(+)-Cl(-) cotransporter, KCC3, in the central and peripheral nervous systems: expression in the choroid plexus, large neurons and white matter tracts.
Gallazzini M, Attmane-Elakeb A, Mount DB, Hebert SC, Bichara M
Regulation by glucocorticoids and osmolality of expression of ROMK (Kir 1.1), the apical K channel of thick ascending limb. Am J Physiol Renal Physiol. 2003 May; 284(5):F977-86.
Regulation by glucocorticoids and osmolality of expression of ROMK (Kir 1.1), the apical K channel of thick ascending limb.
Carbon monoxide stimulates the apical 70-pS K+ channel of the rat thick ascending limb. J Clin Invest. 1999 Apr; 103(7):963-70.
Carbon monoxide stimulates the apical 70-pS K+ channel of the rat thick ascending limb.
Howard HC, Mount DB, Rochefort D, Byun N, Dupré N, Lu J, Fan X, Song L, Rivière JB, Prévost C, Horst J, Simonati A, Lemcke B, Welch R, England R, Zhan FQ, Mercado A, Siesser WB, George AL, McDonald MP, Bouchard JP, Mathieu J, Delpire E, Rouleau GA
The K-Cl cotransporter KCC3 is mutant in a severe peripheral neuropathy associated with agenesis of the corpus callosum. Nat Genet. 2002 Nov; 32(3):384-92.
The K-Cl cotransporter KCC3 is mutant in a severe peripheral neuropathy associated with agenesis of the corpus callosum.
The SLC26 gene family of multifunctional anion exchangers. Pflugers Arch. 2004 Feb; 447(5):710-21.
The SLC26 gene family of multifunctional anion exchangers.
de Los Heros P, Kahle KT, Rinehart J, Bobadilla NA, Vázquez N, San Cristobal P, Mount DB, Lifton RP, Hebert SC, Gamba G
Proceedings of the National Academy of Sciences of the United States of America
WNK3 bypasses the tonicity requirement for K-Cl cotransporter activation via a phosphatase-dependent pathway. Proc Natl Acad Sci U S A. 2006 Feb 07; 103(6):1976-81.
WNK3 bypasses the tonicity requirement for K-Cl cotransporter activation via a phosphatase-dependent pathway.
Lauf PK, Zhang J, Delpire E, Fyffe RE, Mount DB, Adragna NC
Comparative biochemistry and physiology. Part A, Molecular & integrative physiology
K-Cl co-transport: immunocytochemical and functional evidence for more than one KCC isoform in high K and low K sheep erythrocytes. Comp Biochem Physiol A Mol Integr Physiol. 2001 Oct; 130(3):499-509.
Comp Biochem Physiol A Mol Integr Physiol
K-Cl co-transport: immunocytochemical and functional evidence for more than one KCC isoform in high K and low K sheep erythrocytes.
Membrane trafficking and the regulation of NKCC2. Am J Physiol Renal Physiol. 2006 Mar; 290(3):F606-7.
Membrane trafficking and the regulation of NKCC2.
Luyckx VA, Goda FO, Mount DB, Nishio T, Hall A, Hebert SC, Hammond TG, Yu AS
Intrarenal and subcellular localization of rat CLC5. Am J Physiol. 1998 11; 275(5):F761-9.
Intrarenal and subcellular localization of rat CLC5.
Kahle KT, Staley KJ, Nahed BV, Gamba G, Hebert SC, Lifton RP, Mount DB
Roles of the cation-chloride cotransporters in neurological disease. Nat Clin Pract Neurol. 2008 Sep; 4(9):490-503.
Roles of the cation-chloride cotransporters in neurological disease.
Simão S, Pedrosa R, Hopfer U, Mount DB, Jose PA, Soares-da-Silva P
Short-term regulation of the Cl-/HCO3(-) exchanger in immortalized SHR proximal tubular epithelial cells. Biochem Pharmacol. 2008 Jun 01; 75(11):2224-33.
Short-term regulation of the Cl-/HCO3(-) exchanger in immortalized SHR proximal tubular epithelial cells.
Plata C, Sussman CR, Sindic A, Liang JO, Mount DB, Josephs ZM, Chang MH, Romero MF
Zebrafish Slc5a12 encodes an electroneutral sodium monocarboxylate transporter (SMCTn). A comparison with the electrogenic SMCT (SMCTe/Slc5a8). J Biol Chem. 2007 Apr 20; 282(16):11996-2009.
Zebrafish Slc5a12 encodes an electroneutral sodium monocarboxylate transporter (SMCTn). A comparison with the electrogenic SMCT (SMCTe/Slc5a8).
Chen YF, Chou CY, Wilkins RJ, Ellory JC, Mount DB, Shen MR
Motor protein-dependent membrane trafficking of KCl cotransporter-4 is important for cancer cell invasion. Cancer Res. 2009 Nov 15; 69(22):8585-93.
Motor protein-dependent membrane trafficking of KCl cotransporter-4 is important for cancer cell invasion.
Hamburger M, Baraf HS, Adamson TC, Basile J, Bass L, Cole B, Doghramji PP, Guadagnoli GA, Hamburger F, Harford R, Lieberman JA, Mandel DR, Mandelbrot DA, McClain BP, Mizuno E, Morton AH, Mount DB, Pope RS, Rosenthal KG, Setoodeh K, Skosey JL, Edwards NL
2011 recommendations for the diagnosis and management of gout and hyperuricemia. Phys Sportsmed. 2011 Nov; 39(4):98-123.
2011 recommendations for the diagnosis and management of gout and hyperuricemia.
Acton BA, Mahadevan V, Mercado A, Uvarov P, Ding Y, Pressey J, Airaksinen MS, Mount DB, Woodin MA
The Journal of neuroscience : the official journal of the Society for Neuroscience
Hyperpolarizing GABAergic transmission requires the KCC2 C-terminal ISO domain. J Neurosci. 2012 Jun 20; 32(25):8746-51.
Hyperpolarizing GABAergic transmission requires the KCC2 C-terminal ISO domain.
Splicing a kinase and the regulation of salt transport. J Am Soc Nephrol. 2009 Jun; 20(6):1166-8.
Splicing a kinase and the regulation of salt transport.
Mount DB, Baekgaard A, Hall AE, Plata C, Xu J, Beier DR, Gamba G, Hebert SC
Isoforms of the Na-K-2Cl cotransporter in murine TAL I. Molecular characterization and intrarenal localization. Am J Physiol. 1999 03; 276(3):F347-58.
Isoforms of the Na-K-2Cl cotransporter in murine TAL I. Molecular characterization and intrarenal localization.
The Plant journal : for cell and molecular biology
Arabidopsis UVH3 gene is a homolog of the Saccharomyces cerevisiae RAD2 and human XPG DNA repair genes. Plant J. 2001 May; 26(3):329-38.
Arabidopsis UVH3 gene is a homolog of the Saccharomyces cerevisiae RAD2 and human XPG DNA repair genes.
Chauhan S, Pandey R, Way JF, Sroka TC, Demetriou MC, Kunz S, Cress AE, Mount DW, Miesfeld RL
Biochemical and biophysical research communications
Androgen regulation of the human FERM domain encoding gene EHM2 in a cell model of steroid-induced differentiation. Biochem Biophys Res Commun. 2003 Oct 17; 310(2):421-32.
Androgen regulation of the human FERM domain encoding gene EHM2 in a cell model of steroid-induced differentiation.
Electroneutral cation-chloride cotransporters in the central nervous system. Neurochem Res. 2004 Jan; 29(1):17-25.
Electroneutral cation-chloride cotransporters in the central nervous system.
Pandey R, Müller A, Napoli CA, Selinger DA, Pikaard CS, Richards EJ, Bender J, Mount DW, Jorgensen RA
Analysis of histone acetyltransferase and histone deacetylase families of Arabidopsis thaliana suggests functional diversification of chromatin modification among multicellular eukaryotes. Nucleic Acids Res. 2002 Dec 01; 30(23):5036-55.
Analysis of histone acetyltransferase and histone deacetylase families of Arabidopsis thaliana suggests functional diversification of chromatin modification among multicellular eukaryotes.
Novel physiology for an orphan transporter. Curr Opin Nephrol Hypertens. 2004 Sep; 13(5):521-3.
Novel physiology for an orphan transporter.
Regulated endocytosis of NCC. Am J Physiol Renal Physiol. 2010 Aug; 299(2):F297-9.
Advances in experimental medicine and biology
Molecular physiology of mammalian K(+)-Cl- cotransporters. Adv Exp Med Biol. 2004; 559:29-41.
Molecular physiology of mammalian K(+)-Cl- cotransporters.
Nakada T, Zandi-Nejad K, Kurita Y, Kudo H, Broumand V, Kwon CY, Mercado A, Mount DB, Hirose S
American journal of physiology. Regulatory, integrative and comparative physiology
Roles of Slc13a1 and Slc26a1 sulfate transporters of eel kidney in sulfate homeostasis and osmoregulation in freshwater. Am J Physiol Regul Integr Comp Physiol. 2005 Aug; 289(2):R575-R585.
Roles of Slc13a1 and Slc26a1 sulfate transporters of eel kidney in sulfate homeostasis and osmoregulation in freshwater.
Reynolds A, Brustein E, Liao M, Mercado A, Babilonia E, Mount DB, Drapeau P
Neurogenic role of the depolarizing chloride gradient revealed by global overexpression of KCC2 from the onset of development. J Neurosci. 2008 Feb 13; 28(7):1588-97.
Neurogenic role of the depolarizing chloride gradient revealed by global overexpression of KCC2 from the onset of development.
The kidney in hyperuricemia and gout. Curr Opin Nephrol Hypertens. 2013 Mar; 22(2):216-23.
Toka HR, Al-Romaih K, Koshy JM, DiBartolo S, Kos CH, Quinn SJ, Curhan GC, Mount DB, Brown EM, Pollak MR
Deficiency of the calcium-sensing receptor in the kidney causes parathyroid hormone-independent hypocalciuria. J Am Soc Nephrol. 2012 Nov; 23(11):1879-90.
Deficiency of the calcium-sensing receptor in the kidney causes parathyroid hormone-independent hypocalciuria.
Chang MH, Plata C, Zandi-Nejad K, Sindic A, Sussman CR, Mercado A, Broumand V, Raghuram V, Mount DB, Romero MF
Slc26a9--anion exchanger, channel and Na+ transporter. J Membr Biol. 2009 Apr; 228(3):125-40.
Slc26a9--anion exchanger, channel and Na+ transporter.
2011 Recommendations for the diagnosis and management of gout and hyperuricemia. Postgrad Med. 2011 Nov; 123(6 Suppl 1):3-36.
2011 Recommendations for the diagnosis and management of gout and hyperuricemia.
Gibbs JS, Chiou HC, Hall JD, Mount DW, Retondo MJ, Weller SK, Coen DM
Sequence and mapping analyses of the herpes simplex virus DNA polymerase gene predict a C-terminal substrate binding domain. Proc Natl Acad Sci U S A. 1985 Dec; 82(23):7969-73.
Sequence and mapping analyses of the herpes simplex virus DNA polymerase gene predict a C-terminal substrate binding domain.
The molecular physiology of electroneutral cation-chloride cotransport. J Membr Biol. 1997 Aug 01; 158(3):177-86.
The molecular physiology of electroneutral cation-chloride cotransport.
Mercado A, Song L, Vazquez N, Mount DB, Gamba G
Functional comparison of the K+-Cl- cotransporters KCC1 and KCC4. J Biol Chem. 2000 Sep 29; 275(39):30326-34.
Functional comparison of the K+-Cl- cotransporters KCC1 and KCC4.
Steinlein OK, Neubauer BA, Sander T, Song L, Stoodt J, Mount DB
Mutation analysis of the potassium chloride cotransporter KCC3 (SLC12A6) in rolandic and idiopathic generalized epilepsy. Epilepsy Res. 2001 May; 44(2-3):191-5.
Mutation analysis of the potassium chloride cotransporter KCC3 (SLC12A6) in rolandic and idiopathic generalized epilepsy.
Mount DB, Mercado A, Song L, Xu J, George AL, Delpire E, Gamba G
Cloning and characterization of KCC3 and KCC4, new members of the cation-chloride cotransporter gene family. J Biol Chem. 1999 Jun 04; 274(23):16355-62.
Cloning and characterization of KCC3 and KCC4, new members of the cation-chloride cotransporter gene family.
Renal potassium-chloride cotransporters. Curr Opin Nephrol Hypertens. 2001 Sep; 10(5):685-91.
Renal potassium-chloride cotransporters.