Professor of Microbiology and Molecular Genetics, Emeritus
"Up-promoter" mutations of glucose 6-phosphate dehydrogenase in Escherichia coli. J Mol Biol. 1972 Oct 28; 71(1):107-11.
"Up-promoter" mutations of glucose 6-phosphate dehydrogenase in Escherichia coli.
Isolation of specialized transducing bacteriophages for gluconate 6-phosphate dehydrogenase (gnd) of Escherichia coli. J Bacteriol. 1974 Feb; 117(2):468-76.
Isolation of specialized transducing bacteriophages for gluconate 6-phosphate dehydrogenase (gnd) of Escherichia coli.
Proceedings of the National Academy of Sciences of the United States of America
On ras gene function in yeast. Proc Natl Acad Sci U S A. 1985 Jul; 82(14):4740-4.
Involvement of kinases in glucose and fructose uptake by Saccharomyces cerevisiae. Proc Natl Acad Sci U S A. 1983 Mar; 80(6):1730-4.
Involvement of kinases in glucose and fructose uptake by Saccharomyces cerevisiae.
Pathways of NADPH formation in Escherichia coli. J Biol Chem. 1977 May 25; 252(10):3382-91.
Pathways of NADPH formation in Escherichia coli.
Glucose metabolism in gcr mutants of Saccharomyces cerevisiae. J Bacteriol. 1999 Aug; 181(15):4719-23.
Glucose metabolism in gcr mutants of Saccharomyces cerevisiae.
The top genes: on the distance from transcript to function in yeast glycolysis. Curr Opin Microbiol. 2003 Apr; 6(2):198-201.
The top genes: on the distance from transcript to function in yeast glycolysis.
Phenotypic suppression of phosphofructokinase mutations in Escherichia coli by constitutive expression of the glyoxylate shunt. J Bacteriol. 1974 Jun; 118(3):1090-100.
Phenotypic suppression of phosphofructokinase mutations in Escherichia coli by constitutive expression of the glyoxylate shunt.
Fructose bisphosphatase of Saccharomyces cerevisiae. Cloning, disruption and regulation of the FBP1 structural gene. J Mol Biol. 1985 Nov 20; 186(2):307-19.
Fructose bisphosphatase of Saccharomyces cerevisiae. Cloning, disruption and regulation of the FBP1 structural gene.
The specific fructose diphosphatase of Escherichia coli: properties and partial purification. Arch Biochem Biophys. 1966 Apr; 114(1):4-12.
The specific fructose diphosphatase of Escherichia coli: properties and partial purification.
Genetic mapping of mutations affecting phosphoglucose isomerase and fructose diphosphatase in Escherichia coli. J Bacteriol. 1967 May; 93(5):1582-7.
Genetic mapping of mutations affecting phosphoglucose isomerase and fructose diphosphatase in Escherichia coli.
6-phosphogluconolactonase mutants of Escherichia coli and a maltose blue gene. J Bacteriol. 1969 Dec; 100(3):1296-301.
6-phosphogluconolactonase mutants of Escherichia coli and a maltose blue gene.
Glucose and gluconate metabolism in a mutant of Escherichia coli lacking gluconate-6-phosphate dehydrase. J Bacteriol. 1967 May; 93(5):1579-81.
Glucose and gluconate metabolism in a mutant of Escherichia coli lacking gluconate-6-phosphate dehydrase.
The accumulation of glucose 6-phosphate from glucose and its effect in an Escherichia coli mutant lacking phosphoglucose isomerase and glucose 6-phosphate dehydrogenase. J Biol Chem. 1968 Dec 25; 243(24):6451-7.
The accumulation of glucose 6-phosphate from glucose and its effect in an Escherichia coli mutant lacking phosphoglucose isomerase and glucose 6-phosphate dehydrogenase.
Expression of kinase-dependent glucose uptake in Saccharomyces cerevisiae. J Bacteriol. 1984 Sep; 159(3):1013-7.
Expression of kinase-dependent glucose uptake in Saccharomyces cerevisiae.
The biochemical genetics of glycolysis in microbes. Basic Life Sci. 1981; 18:201-15.
The biochemical genetics of glycolysis in microbes.
Biochemical and biophysical research communications
Selection of fructose 6-phosphate kinase mutants in Escherichia coli. Biochem Biophys Res Commun. 1968 Aug 13; 32(3):467-73.
Selection of fructose 6-phosphate kinase mutants in Escherichia coli.
Sugar metabolism in transketolase mutants of Escherichia coli. J Bacteriol. 1974 Jun; 118(3):1082-9.
Sugar metabolism in transketolase mutants of Escherichia coli.
2-keto-3-deoxygluconate 6-phosphate aldolase mutants of Escherichia coli. J Bacteriol. 1971 Dec; 108(3):1277-83.
2-keto-3-deoxygluconate 6-phosphate aldolase mutants of Escherichia coli.
Cloning of genes that complement yeast hexokinase and glucokinase mutants. J Bacteriol. 1983 May; 154(2):1002-4.
Cloning of genes that complement yeast hexokinase and glucokinase mutants.
The gcr (glycolysis regulation) mutation of Saccharomyces cerevisiae. J Biol Chem. 1981 Dec 25; 256(24):13074-8.
The gcr (glycolysis regulation) mutation of Saccharomyces cerevisiae.
The 6-phosphogluconate dehydrogenase reaction in Escherichia coli. J Biol Chem. 1979 Oct 25; 254(20):10237-42.
The 6-phosphogluconate dehydrogenase reaction in Escherichia coli.
Deletion mapping of zwf, the gene for a constitutive enzyme, glucose 6-phosphate dehydrogenase in Escherichia coli. Genetics. 1972 Aug; 71(4):481-9.
Deletion mapping of zwf, the gene for a constitutive enzyme, glucose 6-phosphate dehydrogenase in Escherichia coli.
Tn10 insertions in the pfkB region of Escherichia coli. J Bacteriol. 1981 Sep; 147(3):935-43.
Tn10 insertions in the pfkB region of Escherichia coli.
Saccharomyces carlsbergensis fdp mutant and futile cycling of fructose 6-phosphate. Mol Cell Biol. 1982 Aug; 2(8):921-9.
Saccharomyces carlsbergensis fdp mutant and futile cycling of fructose 6-phosphate.
Babul J, Clifton D, Kretschmer M, Fraenkel DG
Glucose metabolism in Escherichia coli and the effect of increased amount of aldolase. Biochemistry. 1993 May 04; 32(17):4685-92.
Glucose metabolism in Escherichia coli and the effect of increased amount of aldolase.
Phosphorylation of yeast hexokinases. Eur J Biochem. 1990 Jun 20; 190(2):371-5.
An alteration in phosphofructokinase 2 of Escherichia coli which impairs gluconeogenic growth and improves growth on sugars. Eur J Biochem. 1982 Aug; 126(2):373-9.
An alteration in phosphofructokinase 2 of Escherichia coli which impairs gluconeogenic growth and improves growth on sugars.
Transketolase mutants of Escherichia coli. J Bacteriol. 1969 Dec; 100(3):1289-95.
Transketolase mutants of Escherichia coli.
The use of 6-labeled glucose to assess futile cycling in Escherichia coli. J Biol Chem. 1980 Apr 10; 255(7):2867-9.
The use of 6-labeled glucose to assess futile cycling in Escherichia coli.
Bisson LF, Neigeborn L, Carlson M, Fraenkel DG
The SNF3 gene is required for high-affinity glucose transport in Saccharomyces cerevisiae. J Bacteriol. 1987 Apr; 169(4):1656-62.
The SNF3 gene is required for high-affinity glucose transport in Saccharomyces cerevisiae.
Glyceraldehyde 3-phosphate dehydrogenase mutants of Escherichia coli. J Bacteriol. 1975 Jun; 122(3):1175-9.
Glyceraldehyde 3-phosphate dehydrogenase mutants of Escherichia coli.
Setting of graded levels of a protein in yeast by a t-degron technique as applied to phosphoglycerate mutase. BMC Genet. 2002 Jul 30; 3:13.
Setting of graded levels of a protein in yeast by a t-degron technique as applied to phosphoglycerate mutase.
PATHWAYS OF D-GLUCOSE METABOLISM IN SALMONELLA TYPHINMURIUM. A STUDY OF A MUTANT LACKING PHOSPHOGLUCOSE ISOMERASE. J Biol Chem. 1964 Sep; 239:2765-71.
PATHWAYS OF D-GLUCOSE METABOLISM IN SALMONELLA TYPHINMURIUM. A STUDY OF A MUTANT LACKING PHOSPHOGLUCOSE ISOMERASE.
Genetic mapping of loci for glucose-6-phosphate dehydrogenase, gluconate-6-phosphate dehydrogenase, and gluconate-6-phosphate dehydrase in Escherichia coli. J Bacteriol. 1968 Apr; 95(4):1272-8.
Genetic mapping of loci for glucose-6-phosphate dehydrogenase, gluconate-6-phosphate dehydrogenase, and gluconate-6-phosphate dehydrase in Escherichia coli.
Cloning of yeast glycolysis genes by complementation. Biochem Biophys Res Commun. 1982 Oct 15; 108(3):1107-22.
Cloning of yeast glycolysis genes by complementation.
Fructose bisphosphatase of Escherichia coli: cloning of the structural gene (fbp) and preparation of a chromosomal deletion. J Bacteriol. 1984 Jun; 158(3):1048-53.
Fructose bisphosphatase of Escherichia coli: cloning of the structural gene (fbp) and preparation of a chromosomal deletion.
The effect of increased phosphoglucose isomerase on glucose metabolism in Saccharomyces cerevisiae. J Biol Chem. 1994 Feb 18; 269(7):4878-82.
The effect of increased phosphoglucose isomerase on glucose metabolism in Saccharomyces cerevisiae.
AMP-insensitive fructose bisphosphatase in Escherichia coli and its consequences. Proc Natl Acad Sci U S A. 1986 Mar; 83(6):1656-9.
AMP-insensitive fructose bisphosphatase in Escherichia coli and its consequences.
The enzymatic lesion of strain MM-6, a pleiotropic carbohydrate-negative mutant of Escherichia coli. Biochem Biophys Res Commun. 1967 Apr 07; 27(1):63-7.
The enzymatic lesion of strain MM-6, a pleiotropic carbohydrate-negative mutant of Escherichia coli.
Identification and cloning of yeast phosphofructokinase 2. Eur J Biochem. 1991 Apr 23; 197(2):367-72.
Identification and cloning of yeast phosphofructokinase 2.
Yeast hexokinase mutants. J Biol Chem. 1977 Jul 10; 252(13):4443-4.
Mutants in glucose metabolism. Annu Rev Biochem. 1986; 55:317-37.
Phosphate modification of fructose-1,6-bisphosphate aldolase in Escherichia coli. Biochem Biophys Res Commun. 1988 Mar 30; 151(3):1033-8.
Phosphate modification of fructose-1,6-bisphosphate aldolase in Escherichia coli.
Glucose-6-phosphate dehydrogenase from Escherichia coli and from a "high-level" mutant. J Bacteriol. 1972 Apr; 110(1):155-60.
Glucose-6-phosphate dehydrogenase from Escherichia coli and from a "high-level" mutant.
Transport of 6-deoxyglucose in Saccharomyces cerevisiae. J Bacteriol. 1983 Sep; 155(3):995-1000.
Transport of 6-deoxyglucose in Saccharomyces cerevisiae.
Kriegel TM, Rush J, Vojtek AB, Clifton D, Fraenkel DG
In vivo phosphorylation site of hexokinase 2 in Saccharomyces cerevisiae. Biochemistry. 1994 Jan 11; 33(1):148-52.
In vivo phosphorylation site of hexokinase 2 in Saccharomyces cerevisiae.
Hamilton Kuhn Professor of Biological Chemistry and Molecular Pharmacology
David Wesley Gaiser Professor of Biological Chemistry and Molecular Pharmacology
Maude and Lillian Presley Professor of Microbiology and Immunobiology, Emeritus
Elliott T. and Onie H. Adams Professor of Biochemistry and Systems Biology
Professor of Microbiology and Immunobiology, Emeritus
Bullard Professor of Neurobiology, Emeritus
Trehalose-6-phosphate synthase and stabilization of yeast glycolysis. FEMS Yeast Res. 2016 Feb; 16(1):fov100.
Trehalose-6-phosphate synthase and stabilization of yeast glycolysis.
PfkA locus of Escherichia coli. J Bacteriol. 1975 Jun; 122(3):1162-71.
Yeast 6-phosphofructo-2-kinase: sequence and mutant. Biochemistry. 1991 Nov 05; 30(44):10663-72.
Yeast 6-phosphofructo-2-kinase: sequence and mutant.
Allosteric and non-allosteric E. coli phosphofructokinases: effects on growth. Biochem Biophys Res Commun. 1978 Apr 14; 81(3):858-63.
Allosteric and non-allosteric E. coli phosphofructokinases: effects on growth.
Are the aerobic and anaerobic phosphofructokinases of Escherichia coli different? Eur J Biochem. 1977 Apr 15; 74(3):533-7.
Are the aerobic and anaerobic phosphofructokinases of Escherichia coli different?
Glycolysis mutants in Saccharomyces cerevisiae. Genetics. 1978 Jan; 88(1):1-11.
Glycolysis mutants in Saccharomyces cerevisiae.
FRAENKEL DG, FALCOZ-KELLY F, HORECKER BL
THE UTILIZATION OF GLUCOSE 6-PHOSPHATE BY GLUCOKINASELESS AND WILD-TYPE STRAINS OF ESCHERICHIA COLI. Proc Natl Acad Sci U S A. 1964 Nov; 52:1207-13.
THE UTILIZATION OF GLUCOSE 6-PHOSPHATE BY GLUCOKINASELESS AND WILD-TYPE STRAINS OF ESCHERICHIA COLI.
PfkB and pfkC loci of Escherichia coli. J Bacteriol. 1975 Jun; 122(3):1153-61.
gcr2, a new mutation affecting glycolytic gene expression in Saccharomyces cerevisiae. Mol Cell Biol. 1990 Dec; 10(12):6389-96.
gcr2, a new mutation affecting glycolytic gene expression in Saccharomyces cerevisiae.
Suppressor of phosphofructokinase mutations of Escherichia coli. J Bacteriol. 1972 Oct; 112(1):183-7.
Suppressor of phosphofructokinase mutations of Escherichia coli.
Fructose-1, 6-diphosphatase and acid hexose phosphatase of Escherichia coli. J Bacteriol. 1965 Oct; 90(4):837-42.
Fructose-1, 6-diphosphatase and acid hexose phosphatase of Escherichia coli.
Chromosomal location of a gene for fructose 6-phosphate kinase in Escherichia coli. J Bacteriol. 1969 Nov; 100(2):1108-9.
Chromosomal location of a gene for fructose 6-phosphate kinase in Escherichia coli.
Vinopal RT, Hillman JD, Schulman H, Reznikoff WS, Fraenkel DG
New phosphoglucose isomerase mutants of Escherichia coli. J Bacteriol. 1975 Jun; 122(3):1172-4.
New phosphoglucose isomerase mutants of Escherichia coli.
Fructose 2,6-bisphosphate and fructose-6-P 2-kinase in Saccharomyces cerevisiae in relation to metabolic state in wild type and fructose-6-P 1-kinase mutant strains. J Biol Chem. 1983 Aug 10; 258(15):9245-9.
Fructose 2,6-bisphosphate and fructose-6-P 2-kinase in Saccharomyces cerevisiae in relation to metabolic state in wild type and fructose-6-P 1-kinase mutant strains.
Selection of Escherichia coli mutants lacking glucose-6-phosphate dehydrogenase or gluconate-6-phosphate dehydrogenase. J Bacteriol. 1968 Apr; 95(4):1267-71.
Selection of Escherichia coli mutants lacking glucose-6-phosphate dehydrogenase or gluconate-6-phosphate dehydrogenase.
Mutant studies of yeast phosphofructokinase. Biochemistry. 1982 Apr 13; 21(8):1935-42.
Mutant studies of yeast phosphofructokinase.
alpha-Ketoglutarate dehydrogenase mutant of Rhizobium meliloti. J Bacteriol. 1979 Jan; 137(1):415-9.
alpha-Ketoglutarate dehydrogenase mutant of Rhizobium meliloti.
Functional studies of yeast glucokinase. J Bacteriol. 1993 Jun; 175(11):3289-94.
Functional studies of yeast glucokinase.
Genetics and intermediary metabolism. Annu Rev Genet. 1992; 26:159-77.
Microbiology and Immunobiology, Room 1046
Thomson J, Gerstenberger PD, Goldberg DE, Gociar E, Orozco de Silva A, Fraenkel DG
ColE1 hybrid plasmids for Escherichia coli genes of glycolysis and the hexose monophosphate shunt. J Bacteriol. 1979 Jan; 137(1):502-6.
ColE1 hybrid plasmids for Escherichia coli genes of glycolysis and the hexose monophosphate shunt.
Walsh RB, Clifton D, Horak J, Fraenkel DG
Saccharomyces cerevisiae null mutants in glucose phosphorylation: metabolism and invertase expression. Genetics. 1991 Jul; 128(3):521-7.
Saccharomyces cerevisiae null mutants in glucose phosphorylation: metabolism and invertase expression.
A mutation increasing the amount of a constitutive enzyme in Escherichia coli, glucose 6-phosphate dehydrogenase. J Mol Biol. 1971 Feb 28; 56(1):183-94.
A mutation increasing the amount of a constitutive enzyme in Escherichia coli, glucose 6-phosphate dehydrogenase.
Glucose and gluconate metabolism in an Escherichia coli mutant lacking phosphoglucose isomerase. J Bacteriol. 1967 May; 93(5):1571-8.
Glucose and gluconate metabolism in an Escherichia coli mutant lacking phosphoglucose isomerase.
FRAENKEL D, OSBORN MJ, HORECKER BL, SMITH SM
Metabolism and cell wall structure of a mutant of Salmonella typhimurium deficient in phosphoglucose isomerase. Biochem Biophys Res Commun. 1963 Jun 20; 11:423-8.
Metabolism and cell wall structure of a mutant of Salmonella typhimurium deficient in phosphoglucose isomerase.
Glucose metabolism in 6 phosphogluconolactonase mutants of Escherichia coli. J Biol Chem. 1972 Mar 25; 247(6):1904-10.
Glucose metabolism in 6 phosphogluconolactonase mutants of Escherichia coli.
The phosphoenolpyruvate-initiated pathway of fructose metabolism in Escherichia coli. J Biol Chem. 1968 Dec 25; 243(24):6458-63.
The phosphoenolpyruvate-initiated pathway of fructose metabolism in Escherichia coli.
Two fructose 6-phosphate kinase activities in Escherichia coli. J Biol Chem. 1973 Jul 10; 248(13):4865-6.
Two fructose 6-phosphate kinase activities in Escherichia coli.
Assessment of a futile cycle involving reconversion of fructose 6-phosphate to fructose 1,6-bisphosphate during gluconeogenic growth of Escherichia coli. J Bacteriol. 1983 Jan; 153(1):390-4.
Assessment of a futile cycle involving reconversion of fructose 6-phosphate to fructose 1,6-bisphosphate during gluconeogenic growth of Escherichia coli.