SNG7StephenGompertsStephen Neil Gomperts, M.D., Ph.D.42.36241700000000-71.0689370000000074314Gomperts, StephenNeil617/726-2000Associate Professor of Neurologycatalyst:eCommonsLogineCommons Loginprns:coAuthorOfcoauthor ofprns:endDateend dateFaculty Rankprns:fullNamefull nameprns:hasAuthorListauthor listprns:hasFacultyRankhas faculty rankprns:hasNetworkhas networkprns:hasPublicationVenuepublished inprns:informationResourceReferenceinformation resource referenceprns:isPrimaryPositionis primary positionprns:latitudelatitudeprns:longitudelongitudeprns:mainImagephotoprns:maxWeightmaximum weightprns:medlineTAjournal title abbreviationprns:meshDescriptorUIMeSH DescriptorUIprns:meshSemanticGroupNameMeSH semantic group nameprns:minWeightminimum weightprns:numberOfAuthorsnumber of authorsprns:numberOfConnectionsnumber of connectionsprns:numberOfPublicationsnumber of publicationsprns:personIdPerson IDprns:personInPrimaryPositionperson in primary positionprns:physicalNeighborOfphysical neighborprns:positionInDepartmentposition in departmentprns:positionInDivisionposition in divisionprns:predicateNodepredicate nodeprns:principalInvestigatorNameprincipal investigator nameprns:publicationDatepublication dateprns:similarTosimilar toprns:sortOrdersort orderprns:startDatestart dateprns:uniquenessWeightuniqueness weightprns:yearyearAcademic ArticleArticleDocumentbibo:pmidPubMed IdentifierAddressvivo:address1address line 1vivo:address2address line 2vivo:address3address line 3vivo:addressCitycityvivo:addressPostalCodepostal codevivo:addressStatestate or provincevivo:authorInAuthorshipselected publicationsvivo:authorRankauthor rank in publicationAuthorshipDepartmentDivisionGrantvivo:hasResearchArearesearch areasvivo:hasResearcherRoleresearch activitiesvivo:hrJobTitleHR job titleInformation Resourcevivo:linkedAuthorlinked authorvivo:linkedInformationResourcelinked information resourcevivo:mailingAddressmailing addressvivo:middleNamemiddle name or initialvivo:personInPositionpositionsvivo:phoneNumberphonePositionvivo:positionInOrganizationposition in organizationvivo:preferredTitlepreferred titleResearcher Rolevivo:researcherRoleOfresearcher role ofvivo:roleContributesTocontributes tovivo:sponsorAwardIdsponsor award idrdf:predicatepredicaterdf:typetyperdfs:labellabelConceptAgentfoaf:firstNamefirst namefoaf:lastNamelast nameOrganizationPerson23401107Gomperts SN, Johnson KA, Growdon JMovement disorders : official journal of the Movement Disorder SocietyReply: Beyond the limits of detection: failure of PiB imaging to capture true Aß burden. Mov Disord. 2013 Mar; 28(3):407.Mov Disord2013-02-07T00:00:002013Reply: Beyond the limits of detection: failure of PiB imaging to capture true Aß burden.23243071Gomperts SN, Locascio JJ, Rentz D, Santarlasci A, Marquie M, Johnson KA, Growdon JHNeurologyAmyloid is linked to cognitive decline in patients with Parkinson disease without dementia. Neurology. 2013 Jan 01; 80(1):85-91.Neurology2012-12-12T00:00:002012Amyloid is linked to cognitive decline in patients with Parkinson disease without dementia.8625403Gomperts SNCellClustering membrane proteins: It's all coming together with the PSD-95/SAP90 protein family. Cell. 1996 Mar 08; 84(5):659-62.Cell1996-03-08T00:00:001996Clustering membrane proteins: It's all coming together with the PSD-95/SAP90 protein family.Authorship 11849942021-08-31GOMPERTS, STEPHEN N.2018-09-01Imaging Epigenetic Mechanisms in Parkinson's Disease with [11C]MartinostatR21NS109833Principal InvestigatorAuthorship 113525010Authorship 11389941830867052Peterson B, Armstrong M, Galasko D, Galvin JE, Goldman J, Irwin D, Paulson H, Kaufer D, Leverenz J, Lunde A, McKeith IG, Siderowf A, Taylor A, Amodeo K, Barrett M, Domoto-Reilly K, Duda J, Gomperts S, Graff-Radford N, Holden S, Honig L, Huddleston D, Lippa C, Litvan I, Manning C, Marder K, Moussa C, Onyike C, Pagan F, Pantelyat A, Pelak V, Poston K, Quinn J, Richard I, Rosenthal LS, Sabbagh M, Scharre D, Sha S, Shill H, Torres-Yaghi Y, Christie T, Graham T, Richards I, Koehler M, Boeve BAlzheimer's research & therapyLewy Body Dementia Association's Research Centers of Excellence Program: Inaugural Meeting Proceedings. Alzheimers Res Ther. 2019 03 13; 11(1):23.Alzheimers Res Ther2019-03-13T00:00:002019Lewy Body Dementia Association's Research Centers of Excellence Program: Inaugural Meeting Proceedings.30843520Zhou H, Neville KR, Goldstein N, Kabu S, Kausar N, Ye R, Nguyen TT, Gelwan N, Hyman BT, Gomperts SNeLifeCholinergic modulation of hippocampal calcium activity across the sleep-wake cycle. Elife. 2019 03 07; 8.Elife2019-03-07T00:00:002019Cholinergic modulation of hippocampal calcium activity across the sleep-wake cycle.D020961Disorders1022230.822755Lewy Body DiseaseD002243Chemicals & Drugs1102660.842029CarbolinesD016229Chemicals & Drugs59335790.387395Amyloid beta-PeptidesD050483Chemicals & Drugs1464270.81124Dopamine Plasma Membrane Transport ProteinsD010300Disorders74127800.359725Parkinson DiseaseNeurologyRadiologyBrigham and Women's HospitalMassachusetts General HospitalMAS9MichaelSchwarzschildMichael A. Schwarzschild, M.D., Ph.D.42.37904200000000-71.0514810000000019322Schwarzschild, MichaelJulieanne Dorn Professor of NeurologyJJL40JosephLocascioJoseph J Locascio, Ph.D.42.36220530000000-71.0672584000000058173Locascio, JosephAssistant Professor of NeurologyDJS1DennisSelkoeDennis J. Selkoe, M.D.42.33837200000000-71.1032690000000081795Selkoe, DennisVincent and Stella Coates Professor of Neurologic Diseases in the Department of Neurology1148selected publications4.822580.0019846171research areas3.149310.030186244coauthor of73.17459.5301560similar toESR4EricRosenthalEric Scott Rosenthal, M.D.42.36241700000000-71.0689370000000075325Rosenthal, EricAssociate Professor of NeurologyJHG1JohnGrowdonJohn Herbert Growdon, M.D.42.36220530000000-71.0672584000000027875Growdon, JohnProfessor of NeurologyBLE4BrianEdlowBrian Lewis Edlow, M.D.42.36241700000000-71.0689370000000063189Edlow, BrianAssociate Professor of NeurologyXOB1XandraBreakefieldXandra Owens Breakefield, Ph.D.42.36241700000000-71.0689370000000069074Breakefield, XandraProfessor of NeurologyRAS4ReisaSperlingReisa Anne Sperling, M.D.42.33710500000000-71.1023170000000020632Sperling, ReisaProfessor of NeurologyBTH2BradleyHymanBradley Theodore Hyman, M.D., Ph.D.42.37904200000000-71.051481000000004393Hyman, BradleyJohn B. Penney, Jr. Professor of NeurologyDWG3DavidGowDavid Whitcomb Gow, Jr., Ph.D.42.36241700000000-71.0689370000000051552Gow, DavidInstructor in Neurology, Part-timeAuthorship 11614431431221985Kastanenka KV, Calvo-Rodriguez M, Hou SS, Zhou H, Takeda S, Arbel-Ornath M, Lariviere A, Lee YF, Kim A, Hawkes JM, Logan R, Feng D, Chen X, Gomperts SN, Bacskai BJScientific reportsFrequency-dependent exacerbation of Alzheimer's disease neuropathophysiology. Sci Rep. 2019 06 20; 9(1):8964.Sci Rep2019-06-20T00:00:002019Frequency-dependent exacerbation of Alzheimer's disease neuropathophysiology.KK183KseniaKastanenkaKsenia Kastanenka, Ph.D.102598Kastanenka, KseniaAssistant Professor of NeurologyKAJ1KeithJohnsonKeith Alan Johnson, M.D.42.36241700000000-71.0689370000000016670Johnson, KeithProfessor of RadiologyRLT7RonaldThibertRonald L. Thibert, D.O.42.36241700000000-71.0689370000000065880Thibert, RonaldAssociate Professor of NeurologyAuthorship 11653671031243072Shirvan J, Clement N, Ye R, Katz S, Schultz A, Johnson KA, Gomez-Isla T, Frosch M, Growdon JH, Gomperts SNNeurologyNeuropathologic correlates of amyloid and dopamine transporter imaging in Lewy body disease. Neurology. 2019 07 30; 93(5):e476-e484.Neurology2019-06-26T00:00:002019Neuropathologic correlates of amyloid and dopamine transporter imaging in Lewy body disease.true1Associate Professor of NeurologyAssociate Professor of Neurologytrue1Instructor in Neurology, Part-timeInstructor in Neurology, Part-timetrue1Julieanne Dorn Professor of NeurologyJulieanne Dorn Professor of Neurologytrue1Professor of NeurologyProfessor of Neurologytrue1Professor of NeurologyProfessor of Neurologytrue1John B. Penney, Jr. Professor of NeurologyJohn B. Penney, Jr. Professor of Neurologytrue1Assistant Professor of NeurologyAssistant Professor of Neurologytrue1Vincent and Stella Coates Professor of Neurologic Diseases in the Department of NeurologyVincent and Stella Coates Professor of Neurologic Diseases in the Department of Neurologytrue1Professor of NeurologyProfessor of Neurology32059167Ye R, Touroutoglou A, Brickhouse M, Katz S, Growdon JH, Johnson KA, Dickerson BC, Gomperts SNNeuroImage. ClinicalTopography of cortical thinning in the Lewy body diseases. Neuroimage Clin. 2020; 26:102196.Neuroimage Clin2020-01-31T00:00:002020Topography of cortical thinning in the Lewy body diseases.Authorship 12258638Authorship 12373671932241955McKeith IG, Ferman TJ, Thomas AJ, Blanc F, Boeve BF, Fujishiro H, Kantarci K, Muscio C, O'Brien JT, Postuma RB, Aarsland D, Ballard C, Bonanni L, Donaghy P, Emre M, Galvin JE, Galasko D, Goldman JG, Gomperts SN, Honig LS, Ikeda M, Leverenz JB, Lewis SJG, Marder KS, Masellis M, Salmon DP, Taylor JP, Tsuang DW, Walker Z, Tiraboschi PNeurologyResearch criteria for the diagnosis of prodromal dementia with Lewy bodies. Neurology. 2020 04 28; 94(17):743-755.Neurology2020-04-02T00:00:002020Research criteria for the diagnosis of prodromal dementia with Lewy bodies.Authorship 1239231732250320Bakshi R, Macklin EA, Hung AY, Hayes MT, Hyman BT, Wills AM, Gomperts SN, Growdon JH, Ascherio A, Scherzer CR, Schwarzschild MAJournal of Parkinson's diseaseAssociations of Lower Caffeine Intake and Plasma Urate Levels with Idiopathic Parkinson's Disease in the Harvard Biomarkers Study. J Parkinsons Dis. 2020; 10(2):505-510.J Parkinsons Dis2020-01-01T00:00:002020Associations of Lower Caffeine Intake and Plasma Urate Levels with Idiopathic Parkinson's Disease in the Harvard Biomarkers Study.true1Associate Professor of NeurologyAssociate Professor of NeurologyAuthorship 12544591732540937Huh YE, Chiang MSR, Locascio JJ, Liao Z, Liu G, Choudhury K, Kuras YI, Tuncali I, Videnovic A, Hunt AL, Schwarzschild MA, Hung AY, Herrington TM, Hayes MT, Hyman BT, Wills AM, Gomperts SN, Growdon JH, Sardi SP, Scherzer CRNeurologyß-Glucocerebrosidase activity in GBA-linked Parkinson disease: The type of mutation matters. Neurology. 2020 08 11; 95(6):e685-e696.Neurology2020-06-15T00:00:002020ß-Glucocerebrosidase activity in GBA-linked Parkinson disease: The type of mutation matters.Authorship 13280661233578418Goodheart AE, Locascio JJ, Samore WR, Collins JA, Brickhouse M, Schultz A, Touroutoglou A, Johnson KA, Frosch MP, Growdon JH, Dickerson BC, Gomperts SNBrain : a journal of neurology18F-AV-1451 positron emission tomography in neuropathological substrates of corticobasal syndrome. Brain. 2021 02 12; 144(1):266-277.Brain2021-02-12T00:00:00202118F-AV-1451 positron emission tomography in neuropathological substrates of corticobasal syndrome.Authorship 1335210633639572Ye R, Locascio JJ, Goodheart AE, Quan M, Zhang B, Gomperts SNParkinsonism & related disordersSerum NFL levels predict progression of motor impairment and reduction in putamen dopamine transporter binding ratios in de novo Parkinson's disease: An 8-year longitudinal study. Parkinsonism Relat Disord. 2021 04; 85:11-16.Parkinsonism Relat Disord2021-02-17T00:00:002021Serum NFL levels predict progression of motor impairment and reduction in putamen dopamine transporter binding ratios in de novo Parkinson's disease: An 8-year longitudinal study.2023-08-31GOMPERTS, EDWARD ;GOMPERTS, STEPHEN N.2021-09-20HBI-002 to Treat Parkinson’s DiseaseR41NS122576Principal Investigator2022-08-31GOMPERTS, STEPHEN N.2021-09-30Imaging Epigenetic Mechanisms in the Lewy Body Dementias with [11C]MartinostatR56AG070827Principal InvestigatorAuthorship 14354761435173668Scott GD, Arnold MR, Beach TG, Gibbons CH, Kanthasamy AG, Lebovitz RM, Lemstra AW, Shaw LM, Teunissen CE, Zetterberg H, Taylor AS, Graham TC, Boeve BF, Gomperts SN, Graff-Radford NR, Moussa C, Poston KL, Rosenthal LS, Sabbagh MN, Walsh RR, Weber MT, Armstrong MJ, Bang JA, Bozoki AC, Domoto-Reilly K, Duda JE, Fleisher JE, Galasko DR, Galvin JE, Goldman JG, Holden SK, Honig LS, Huddleston DE, Leverenz JB, Litvan I, Manning CA, Marder KS, Pantelyat AY, Pelak VS, Scharre DW, Sha SJ, Shill HA, Mari Z, Quinn JF, Irwin DJFrontiers in neurologyFluid and Tissue Biomarkers of Lewy Body Dementia: Report of an LBDA Symposium. Front Neurol. 2021; 12:805135.Front Neurol2022-01-31T00:00:002022Fluid and Tissue Biomarkers of Lewy Body Dementia: Report of an LBDA Symposium.Authorship 2994241true1Assistant Professor of NeurologyAssistant Professor of Neurologytrue1Associate Professor of NeurologyAssociate Professor of NeurologyAuthorship 1492010336130946Jiang Y, Alam JJ, Gomperts SN, Maruff P, Lemstra AW, Germann UA, Stavrides PH, Darji S, Malampati S, Peddy J, Bleiwas C, Pawlik M, Pensalfini A, Yang DS, Subbanna S, Basavarajappa BS, Smiley JF, Gardner A, Blackburn K, Chu HM, Prins ND, Teunissen CE, Harrison JE, Scheltens P, Nixon RANature communicationsPreclinical and randomized clinical evaluation of the p38a kinase inhibitor neflamapimod for basal forebrain cholinergic degeneration. Nat Commun. 2022 09 21; 13(1):5308.Nat Commun2022-09-21T00:00:002022Preclinical and randomized clinical evaluation of the p38a kinase inhibitor neflamapimod for basal forebrain cholinergic degeneration.Authorship 1509239636471155Zhou H, Li H, Gowravaram N, Quan M, Kausar N, Gomperts SNScientific reportsDisruption of hippocampal neuronal circuit function depends upon behavioral state in the APP/PS1 mouse model of Alzheimer's disease. Sci Rep. 2022 12 05; 12(1):21022.Sci Rep2022-12-05T00:00:002022Disruption of hippocampal neuronal circuit function depends upon behavioral state in the APP/PS1 mouse model of Alzheimer's disease.36641682Azami H, Moguilner S, Penagos H, Sarkis RA, Arnold SE, Gomperts SN, Lam ADJournal of Alzheimer's disease : JADEEG Entropy in REM Sleep as a Physiologic Biomarker in Early Clinical Stages of Alzheimer's Disease. J Alzheimers Dis. 2023; 91(4):1557-1572.J Alzheimers Dis2023-01-01T00:00:002023EEG Entropy in REM Sleep as a Physiologic Biomarker in Early Clinical Stages of Alzheimer's Disease.Authorship 15157466true1Instructor in NeurologyInstructor in Neurologytrue1Associate Professor of NeurologyAssociate Professor of NeurologyAuthorship 156142211Authorship 15733951037163040Lee YF, Russ AN, Zhao Q, Maci M, Miller MR, Hou SS, Algamal M, Zhao Z, Li H, Gelwan N, Gomperts SN, Araque A, Galea E, Bacskai BJ, Kastanenka KVResearch squareOptogenetic Targeting of Astrocytes Restores Slow Brain Rhythm Function and Slows Alzheimer's Disease Pathology. Res Sq. 2023 Apr 25.Res Sq2023-04-25T00:00:002023Optogenetic Targeting of Astrocytes Restores Slow Brain Rhythm Function and Slows Alzheimer's Disease Pathology.37398030Rose KN, Zorlu M, Xue X, Fassini A, Cai W, Lin S, Webb P, Schwarzschild MA, Chen X, Gomperts SNbioRxiv : the preprint server for biologyNeuroprotection of low dose carbon monoxide in Parkinson's disease models commensurate with the reduced risk of Parkinson's among smokers. bioRxiv. 2024 Feb 11.bioRxiv2024-02-11T00:00:002024Neuroprotection of low dose carbon monoxide in Parkinson's disease models commensurate with the reduced risk of Parkinson's among smokers.Authorship 158448813Authorship 1590986637657939Alam JJ, Maruff P, Doctrow SR, Chu HM, Conway J, Gomperts SN, Teunissen CNeurologyAssociation of Plasma Phosphorylated Tau With the Response to Neflamapimod Treatment in Patients With Dementia With Lewy Bodies. Neurology. 2023 10 24; 101(17):e1708-e1717.Neurology2023-09-01T00:00:002023Association of Plasma Phosphorylated Tau With the Response to Neflamapimod Treatment in Patients With Dementia With Lewy Bodies.37567942Lee YF, Russ AN, Zhao Q, Perle SJ, Maci M, Miller MR, Hou SS, Algamal M, Zhao Z, Li H, Gelwan N, Liu Z, Gomperts SN, Araque A, Galea E, Bacskai BJ, Kastanenka KVScientific reportsOptogenetic targeting of astrocytes restores slow brain rhythm function and slows Alzheimer's disease pathology. Sci Rep. 2023 08 11; 13(1):13075.Sci Rep2023-08-11T00:00:002023Optogenetic targeting of astrocytes restores slow brain rhythm function and slows Alzheimer's disease pathology.true1Professor of RadiologyProfessor of RadiologyAuthorship 16088351438041158Zhao Q, Maci M, Miller MR, Zhou H, Zhang F, Algamal M, Lee YF, Hou SS, Perle SJ, Le H, Russ AN, Lo EH, Gerashchenko D, Gomperts SN, Bacskai BJ, Kastanenka KVMolecular neurodegenerationSleep restoration by optogenetic targeting of GABAergic neurons reprograms microglia and ameliorates pathological phenotypes in an Alzheimer's disease model. Mol Neurodegener. 2023 Dec 01; 18(1):93.Mol Neurodegener2023-12-01T00:00:002023Sleep restoration by optogenetic targeting of GABAergic neurons reprograms microglia and ameliorates pathological phenotypes in an Alzheimer's disease model.Authorship 16200321838196602Olsen A, Locascio J, Tuncali I, Laroussi N, Abatzis E, Kamenskaya P, Kuras Y, Yi T, Videnovic A, Hayes M, Ho G, Paulson J, Khurana V, Herrington T, Hyman B, Selkoe D, Growdon J, Gomperts S, Riise T, Schwarzschild M, Hung A, Wills A, Scherzer CResearch squareHealth phenome of Parkinson's patients reveals prominent mood-sleep cluster. Res Sq. 2023 Dec 22.Res Sq2023-12-22T00:00:002023Health phenome of Parkinson's patients reveals prominent mood-sleep cluster.Authorship 1621341338226487Rose KN, Schwarzschild MA, Gomperts SNMovement disorders : official journal of the Movement Disorder SocietyClearing the Smoke: What Protects Smokers from Parkinson's Disease? Mov Disord. 2024 Feb; 39(2):267-272.Mov Disord2024-01-16T00:00:002024Clearing the Smoke: What Protects Smokers from Parkinson's Disease?Authorship 16234181138265159Agarwal K, Backler W, Bayram E, Bloom L, Boeve BF, Cha JH, Denslow M, Ferman TJ, Galasko D, Galvin JE, Gomperts SN, Irizarry MC, Kantarci K, Kaushik H, Kietlinski M, Koenig A, Leverenz JB, McKeith I, McLean PJ, Montine TJ, Moose SO, O'Brien JT, Panier V, Ramanathan S, Ringel MS, Scholz SW, Small J, Sperling RA, Taylor A, Taylor JP, Ward RA, Witten L, Hyman BTAlzheimer's & dementia : the journal of the Alzheimer's AssociationLewy body dementia: Overcoming barriers and identifying solutions. Alzheimers Dement. 2024 Jan 24.Alzheimers Dement2024-01-24T00:00:002024Lewy body dementia: Overcoming barriers and identifying solutions.24068787Ding H, Dhima K, Lockhart KC, Locascio JJ, Hoesing AN, Duong K, Trisini-Lipsanopoulos A, Hayes MT, Sohur US, Wills AM, Mollenhauer B, Flaherty AW, Hung AY, Mejia N, Khurana V, Gomperts SN, Selkoe DJ, Schwarzschild MA, Schlossmacher MG, Hyman BT, Sudarsky LR, Growdon JH, Scherzer CRNeurologyUnrecognized vitamin D3 deficiency is common in Parkinson disease: Harvard Biomarker Study. Neurology. 2013 Oct 22; 81(17):1531-7.Neurology2013-09-25T00:00:002013Unrecognized vitamin D3 deficiency is common in Parkinson disease: Harvard Biomarker Study.Authorship 2578452Authorship 68113116Authorship 3237741Authorship 696143224102128Chen Z, Gomperts SN, Yamamoto J, Wilson MANeural computationNeural representation of spatial topology in the rodent hippocampus. Neural Comput. 2014 Jan; 26(1):1-39.Neural Comput2013-10-08T00:00:002013Neural representation of spatial topology in the rodent hippocampus.Authorship 2845131Authorship 742514125011528Gomperts SNCurrent neurology and neuroscience reportsImaging the role of amyloid in PD dementia and dementia with Lewy bodies. Curr Neurol Neurosci Rep. 2014 Aug; 14(8):472.Curr Neurol Neurosci Rep2014-08-01T00:00:002014Imaging the role of amyloid in PD dementia and dementia with Lewy bodies.Authorship 3862611Authorship 776293825429309Marquie M, Locascio JJ, Rentz DM, Becker JA, Hedden T, Johnson KA, Growdon JH, Gomperts SNAlzheimer's research & therapyStriatal and extrastriatal dopamine transporter levels relate to cognition in Lewy body diseases: an (11)C altropane positron emission tomography study. Alzheimers Res Ther. 2014; 6(5-8):52.Alzheimers Res Ther2014-08-27T00:00:002014Striatal and extrastriatal dopamine transporter levels relate to cognition in Lewy body diseases: an (11)C altropane positron emission tomography study.Authorship 5410881Authorship 3727943Authorship 4439651Authorship 1682152AEG32AnnaGoodheartAnna Embardo Goodheart, M.D.138551Goodheart, AnnaInstructor in NeurologyAuthorship 813819226137443Rieckmann A, Gomperts SN, Johnson KA, Growdon JH, Van Dijk KRNeuroImage. ClinicalPutamen-midbrain functional connectivity is related to striatal dopamine transporter availability in patients with Lewy body diseases. Neuroimage Clin. 2015; 8:554-9.Neuroimage Clin2015-06-09T00:00:002015Putamen-midbrain functional connectivity is related to striatal dopamine transporter availability in patients with Lewy body diseases.Authorship 8427831326344059Marquié M, Normandin MD, Vanderburg CR, Costantino IM, Bien EA, Rycyna LG, Klunk WE, Mathis CA, Ikonomovic MD, Debnath ML, Vasdev N, Dickerson BC, Gomperts SN, Growdon JH, Johnson KA, Frosch MP, Hyman BT, Gómez-Isla TAnnals of neurologyValidating novel tau positron emission tomography tracer [F-18]-AV-1451 (T807) on postmortem brain tissue. Ann Neurol. 2015 Nov; 78(5):787-800.Ann Neurol2015-09-25T00:00:002015Validating novel tau positron emission tomography tracer [F-18]-AV-1451 (T807) on postmortem brain tissue.Authorship 8536881Authorship 853107126465113Gomperts SN, Kloosterman F, Wilson MAeLifeVTA neurons coordinate with the hippocampal reactivation of spatial experience. Elife. 2015 Oct 14; 4.Elife2015-10-14T00:00:002015VTA neurons coordinate with the hippocampal reactivation of spatial experience.26655867Gomperts SN, Marquie M, Locascio JJ, Bayer S, Johnson KA, Growdon JHNeuro-degenerative diseasesPET Radioligands Reveal the Basis of Dementia in Parkinson's Disease and Dementia with Lewy Bodies. Neurodegener Dis. 2016; 16(1-2):118-24.Neurodegener Dis2015-12-08T00:00:002015PET Radioligands Reveal the Basis of Dementia in Parkinson's Disease and Dementia with Lewy Bodies.Authorship 874242127042903Gomperts SNContinuum (Minneapolis, Minn.)Lewy Body Dementias: Dementia With Lewy Bodies and Parkinson Disease Dementia. Continuum (Minneap Minn). 2016 Apr; 22(2 Dementia):435-63.Continuum (Minneap Minn)2016-04-01T00:00:002016Lewy Body Dementias: Dementia With Lewy Bodies and Parkinson Disease Dementia.2Assistant Professor1Associate Professor0Full Professor4InstructorAuthorship 8628112016-08-31GOMPERTS, STEPHEN N.2014-09-15PET imaging of hyperphosphorylated tau differentiates PSP and CBD from PDR21NS0902432013-11-30GOMPERTS, STEPHEN N.2008-06-01Ventral Tegmental Area and Hippocampal Interactions in Reinforced Spatial LearninK08MH081027Principal InvestigatorPrincipal InvestigatorAuthorship 933881127654968Gomperts SN, Locascio JJ, Makaretz SJ, Schultz A, Caso C, Vasdev N, Sperling R, Growdon JH, Dickerson BC, Johnson KJAMA neurologyTau Positron Emission Tomographic Imaging in the Lewy Body Diseases. JAMA Neurol. 2016 Nov 01; 73(11):1334-1341.JAMA Neurol2016-11-01T00:00:002016Tau Positron Emission Tomographic Imaging in the Lewy Body Diseases.Authorship 9441771727997036Marquié M, Normandin MD, Meltzer AC, Siao Tick Chong M, Andrea NV, Antón-Fernández A, Klunk WE, Mathis CA, Ikonomovic MD, Debnath M, Bien EA, Vanderburg CR, Costantino I, Makaretz S, DeVos SL, Oakley DH, Gomperts SN, Growdon JH, Domoto-Reilly K, Lucente D, Dickerson BC, Frosch MP, Hyman BT, Johnson KA, Gómez-Isla TAnnals of neurologyPathological correlations of [F-18]-AV-1451 imaging in non-alzheimer tauopathies. Ann Neurol. 2017 Jan; 81(1):117-128.Ann Neurol2017-01-01T00:00:002017Pathological correlations of [F-18]-AV-1451 imaging in non-alzheimer tauopathies.Authorship 970173528241163Xia C, Makaretz SJ, Caso C, McGinnis S, Gomperts SN, Sepulcre J, Gomez-Isla T, Hyman BT, Schultz A, Vasdev N, Johnson KA, Dickerson BCJAMA neurologyAssociation of In Vivo [18F]AV-1451 Tau PET Imaging Results With Cortical Atrophy and Symptoms in Typical and Atypical Alzheimer Disease. JAMA Neurol. 2017 04 01; 74(4):427-436.JAMA Neurol2017-04-01T00:00:002017Association of In Vivo [18F]AV-1451 Tau PET Imaging Results With Cortical Atrophy and Symptoms in Typical and Atypical Alzheimer Disease.114 16th StreetMassachusetts General HospitalCny 2004114 16th StreetCharlestown02129MA9883736Gomperts SN, Rao A, Craig AM, Malenka RC, Nicoll RANeuronPostsynaptically silent synapses in single neuron cultures. Neuron. 1998 Dec; 21(6):1443-51.Neuron1998-12-01T00:00:001998Postsynaptically silent synapses in single neuron cultures.10704498Gomperts SN, Carroll R, Malenka RC, Nicoll RAThe Journal of neuroscience : the official journal of the Society for NeuroscienceDistinct roles for ionotropic and metabotropic glutamate receptors in the maturation of excitatory synapses. J Neurosci. 2000 Mar 15; 20(6):2229-37.J Neurosci2000-03-15T00:00:002000Distinct roles for ionotropic and metabotropic glutamate receptors in the maturation of excitatory synapses.9618545Lissin DV, Gomperts SN, Carroll RC, Christine CW, Kalman D, Kitamura M, Hardy S, Nicoll RA, Malenka RC, von Zastrow MProceedings of the National Academy of Sciences of the United States of AmericaActivity differentially regulates the surface expression of synaptic AMPA and NMDA glutamate receptors. Proc Natl Acad Sci U S A. 1998 Jun 09; 95(12):7097-102.Proc Natl Acad Sci U S A1998-06-09T00:00:001998Activity differentially regulates the surface expression of synaptic AMPA and NMDA glutamate receptors.Authorship 9872412828592453McKeith IG, Boeve BF, Dickson DW, Halliday G, Taylor JP, Weintraub D, Aarsland D, Galvin J, Attems J, Ballard CG, Bayston A, Beach TG, Blanc F, Bohnen N, Bonanni L, Bras J, Brundin P, Burn D, Chen-Plotkin A, Duda JE, El-Agnaf O, Feldman H, Ferman TJ, Ffytche D, Fujishiro H, Galasko D, Goldman JG, Gomperts SN, Graff-Radford NR, Honig LS, Iranzo A, Kantarci K, Kaufer D, Kukull W, Lee VMY, Leverenz JB, Lewis S, Lippa C, Lunde A, Masellis M, Masliah E, McLean P, Mollenhauer B, Montine TJ, Moreno E, Mori E, Murray M, O'Brien JT, Orimo S, Postuma RB, Ramaswamy S, Ross OA, Salmon DP, Singleton A, Taylor A, Thomas A, Tiraboschi P, Toledo JB, Trojanowski JQ, Tsuang D, Walker Z, Yamada M, Kosaka KNeurologyDiagnosis and management of dementia with Lewy bodies: Fourth consensus report of the DLB Consortium. Neurology. 2017 Jul 04; 89(1):88-100.Neurology2017-06-07T00:00:002017Diagnosis and management of dementia with Lewy bodies: Fourth consensus report of the DLB Consortium.10233170Kalman D, Gomperts SN, Hardy S, Kitamura M, Bishop JMMolecular biology of the cellRas family GTPases control growth of astrocyte processes. Mol Biol Cell. 1999 May; 10(5):1665-83.Mol Biol Cell1999-05-01T00:00:001999Ras family GTPases control growth of astrocyte processes.18794492Gomperts SN, Rentz DM, Moran E, Becker JA, Locascio JJ, Klunk WE, Mathis CA, Elmaleh DR, Shoup T, Fischman AJ, Hyman BT, Growdon JH, Johnson KANeurologyImaging amyloid deposition in Lewy body diseases. Neurology. 2008 Sep 16; 71(12):903-10.Neurology2008-09-16T00:00:002008Imaging amyloid deposition in Lewy body diseases.19387422Nguyen DP, Layton SP, Hale G, Gomperts SN, Davidson TJ, Kloosterman F, Wilson MAJournal of visualized experiments : JoVEMicro-drive array for chronic in vivo recording: tetrode assembly. J Vis Exp. 2009 Apr 22; (26).J Vis Exp2009-04-22T00:00:002009Micro-drive array for chronic in vivo recording: tetrode assembly.19381129Kloosterman F, Davidson TJ, Gomperts SN, Layton SP, Hale G, Nguyen DP, Wilson MAJournal of visualized experiments : JoVEMicro-drive array for chronic in vivo recording: drive fabrication. J Vis Exp. 2009 Apr 20; (26).J Vis Exp2009-04-20T00:00:002009Micro-drive array for chronic in vivo recording: drive fabrication.2022-04-30GOMPERTS, STEPHEN N.2017-08-15Impact of Amyloid Beta on Hippocampal Neurophysiology and Calcium Activity across the Sleep-Wake CycleR01AG054551Principal InvestigatorAuthorship 10170081928980714Schonhaut DR, McMillan CT, Spina S, Dickerson BC, Siderowf A, Devous MD, Tsai R, Winer J, Russell DS, Litvan I, Roberson ED, Seeley WW, Grinberg LT, Kramer JH, Miller BL, Pressman P, Nasrallah I, Baker SL, Gomperts SN, Johnson KA, Grossman M, Jagust WJ, Boxer AL, Rabinovici GDAnnals of neurology18 F-flortaucipir tau positron emission tomography distinguishes established progressive supranuclear palsy from controls and Parkinson disease: A multicenter study. Ann Neurol. 2017 Oct; 82(4):622-634.Ann Neurol2017-10-01T00:00:00201718 F-flortaucipir tau positron emission tomography distinguishes established progressive supranuclear palsy from controls and Parkinson disease: A multicenter study.Authorship 10194161329047416Marquié M, Verwer EE, Meltzer AC, Kim SJW, Agüero C, Gonzalez J, Makaretz SJ, Siao Tick Chong M, Ramanan P, Amaral AC, Normandin MD, Vanderburg CR, Gomperts SN, Johnson KA, Frosch MP, Gómez-Isla TActa neuropathologica communicationsLessons learned about [F-18]-AV-1451 off-target binding from an autopsy-confirmed Parkinson's case. Acta Neuropathol Commun. 2017 10 19; 5(1):75.Acta Neuropathol Commun2017-10-19T00:00:002017Lessons learned about [F-18]-AV-1451 off-target binding from an autopsy-confirmed Parkinson's case.22693110Gomperts SN, Locascio JJ, Marquie M, Santarlasci AL, Rentz DM, Maye J, Johnson KA, Growdon JHMovement disorders : official journal of the Movement Disorder SocietyBrain amyloid and cognition in Lewy body diseases. Mov Disord. 2012 Jul; 27(8):965-73.Mov Disord2012-06-12T00:00:002012Brain amyloid and cognition in Lewy body diseases.