McClatchey, Andrea
eCommons Login: AIM1
first name: Andrea
last name: McClatchey
coauthor of: Cichowski, Karen
coauthor of: Georgopoulos, Katia
coauthor of: MacKenzie, Christine
coauthor of: Stott, Shannon
coauthor of: Gusella, James
full name: Andrea I. McClatchey, Ph.D.
has faculty rank: Full Professor
has network: selected publications
has network: research areas
has network: coauthor of
has network: similar to
latitude: 42.37730000000000
longitude: -71.05250000000000
Person ID: 3924
person in primary position: Professor of Pathology
physical neighbor: Franceschini, Maria
physical neighbor: Jenkins, Bruce
physical neighbor: Langenau, David
physical neighbor: Rivera, Miguel
physical neighbor: Sgroi, Dennis
similar to: Plotkin, Scott
similar to: Perrimon, Norbert
similar to: Ramesh, Vijaya
similar to: Stemmer-Rachamimov, Anat
similar to: Mitchison, Timothy
type: Agent
type: Person
selected publications: Authorship 1700408
selected publications: Authorship 1534143
selected publications: Authorship 1354544
selected publications: Authorship 1264989
selected publications: Authorship 1119023
selected publications: Authorship 1089249
selected publications: Authorship 1006937
selected publications: Authorship 1063366
selected publications: Authorship 1043188
selected publications: Authorship 842723
selected publications: Authorship 963421
selected publications: Authorship 769857
selected publications: Authorship 748036
selected publications: Authorship 729160
selected publications: Authorship 714309
selected publications: Authorship 680765
selected publications: Authorship 207080
selected publications: Authorship 188173
selected publications: Authorship 212829
selected publications: Authorship 181978
selected publications: Authorship 448957
selected publications: Authorship 61348
selected publications: Authorship 253546
selected publications: Authorship 246949
selected publications: Authorship 11556
selected publications: Authorship 197
selected publications: Authorship 304949
selected publications: Authorship 372883
selected publications: Authorship 454353
selected publications: Authorship 563152
selected publications: Authorship 304975
selected publications: Authorship 320462
selected publications: Authorship 380985
selected publications: Authorship 155025
selected publications: Authorship 525676
selected publications: Authorship 354323
selected publications: Authorship 501328
selected publications: Authorship 153810
selected publications: Authorship 324338
selected publications: Authorship 31011
selected publications: Authorship 112898
selected publications: Authorship 510299
selected publications: Authorship 459747
selected publications: Authorship 562383
selected publications: Authorship 276455
selected publications: Authorship 321825
selected publications: Authorship 203984
selected publications: Authorship 431753
selected publications: Authorship 73513

eCommons Login
tag name: catalyst:eCommonsLogin
type: DatatypeProperty

coauthor of
tag name: prns:coAuthorOf
type: ObjectProperty

end date
tag name: prns:endDate
type: DatatypeProperty

Faculty Rank
type: Class

full name
tag name: prns:fullName
type: DatatypeProperty

author list
tag name: prns:hasAuthorList
type: DatatypeProperty

has faculty rank
tag name: prns:hasFacultyRank
type: ObjectProperty

has network
tag name: prns:hasNetwork
type: ObjectProperty

published in
tag name: prns:hasPublicationVenue
type: DatatypeProperty

information resource reference
tag name: prns:informationResourceReference
type: DatatypeProperty

is primary position
tag name: prns:isPrimaryPosition
type: DatatypeProperty

latitude
tag name: prns:latitude
type: DatatypeProperty

longitude
tag name: prns:longitude
type: DatatypeProperty

photo
tag name: prns:mainImage
type: ObjectProperty

maximum weight
tag name: prns:maxWeight
type: DatatypeProperty

journal title abbreviation
tag name: prns:medlineTA
type: DatatypeProperty

MeSH DescriptorUI
tag name: prns:meshDescriptorUI
type: DatatypeProperty

MeSH semantic group name
tag name: prns:meshSemanticGroupName
type: DatatypeProperty

minimum weight
tag name: prns:minWeight
type: DatatypeProperty

number of authors
tag name: prns:numberOfAuthors
type: DatatypeProperty

number of connections
tag name: prns:numberOfConnections
type: DatatypeProperty

number of publications
tag name: prns:numberOfPublications
type: DatatypeProperty

Person ID
tag name: prns:personId
type: DatatypeProperty

person in primary position
tag name: prns:personInPrimaryPosition
type: ObjectProperty

physical neighbor
tag name: prns:physicalNeighborOf
type: ObjectProperty

position in department
tag name: prns:positionInDepartment
type: ObjectProperty

position in division
tag name: prns:positionInDivision
type: ObjectProperty

predicate node
tag name: prns:predicateNode
type: ObjectProperty

principal investigator name
tag name: prns:principalInvestigatorName
type: DatatypeProperty

publication date
tag name: prns:publicationDate
type: DatatypeProperty

similar to
tag name: prns:similarTo
type: ObjectProperty

sort order
tag name: prns:sortOrder
type: DatatypeProperty

start date
tag name: prns:startDate
type: DatatypeProperty

uniqueness weight
tag name: prns:uniquenessWeight
type: DatatypeProperty

year
tag name: prns:year
type: DatatypeProperty

Academic Article
type: Class

Article
type: Class

Document
type: Class

PubMed Identifier
tag name: bibo:pmid
type: DatatypeProperty

Address
type: Class

address line 1
tag name: vivo:address1
type: DatatypeProperty

address line 2
tag name: vivo:address2
type: DatatypeProperty

address line 3
tag name: vivo:address3
type: DatatypeProperty

city
tag name: vivo:addressCity
type: DatatypeProperty
type: FunctionalProperty

postal code
tag name: vivo:addressPostalCode
type: DatatypeProperty
type: FunctionalProperty

state or province
tag name: vivo:addressState
type: DatatypeProperty
type: FunctionalProperty

selected publications
tag name: vivo:authorInAuthorship
type: ObjectProperty

author rank in publication
tag name: vivo:authorRank
type: DatatypeProperty
type: FunctionalProperty

Authorship
type: Class

Department
type: Class

Division
type: Class

Grant
type: Class

research areas
tag name: vivo:hasResearchArea
type: ObjectProperty

research activities
tag name: vivo:hasResearcherRole
type: ObjectProperty

HR job title
tag name: vivo:hrJobTitle
type: DatatypeProperty

Information Resource
type: Class

linked author
tag name: vivo:linkedAuthor
type: ObjectProperty

linked information resource
tag name: vivo:linkedInformationResource
type: ObjectProperty

mailing address
tag name: vivo:mailingAddress
type: ObjectProperty

middle name or initial
tag name: vivo:middleName
type: DatatypeProperty
type: FunctionalProperty

positions
tag name: vivo:personInPosition
type: ObjectProperty

phone
tag name: vivo:phoneNumber
type: DatatypeProperty

Position
type: Class

position in organization
tag name: vivo:positionInOrganization
type: ObjectProperty

preferred title
tag name: vivo:preferredTitle
type: DatatypeProperty
type: FunctionalProperty

Researcher Role
type: Class

researcher role of
tag name: vivo:researcherRoleOf
type: ObjectProperty

contributes to
tag name: vivo:roleContributesTo
type: ObjectProperty

sponsor award id
tag name: vivo:sponsorAwardId
type: DatatypeProperty
type: FunctionalProperty

predicate
tag name: rdf:predicate
type: ObjectProperty

type
tag name: rdf:type
type: ObjectProperty

label
tag name: rdfs:label
type: DatatypeProperty

Concept
type: Class

Agent
type: Class

first name
tag name: foaf:firstName
type: DatatypeProperty
type: FunctionalProperty

last name
tag name: foaf:lastName
type: DatatypeProperty
type: FunctionalProperty

Organization
type: Class

Person
type: Class

Authorship 103617
type: Authorship
author rank in publication: 3
linked author: McClatchey, Andrea
linked information resource: Sequence-tagged sites (STSs) spanning 4p16.3 and the Huntington disease candidate region.

Consensus recommendations to accelerate clinical trials for neurofibromatosis type 2.
PubMed Identifier: 19671848
author list: Evans DG, Kalamarides M, Hunter-Schaedle K, Blakeley J, Allen J, Babovic-Vuskanovic D, Belzberg A, Bollag G, Chen R, DiTomaso E, Golfinos J, Harris G, Jacob A, Kalpana G, Karajannis M, Korf B, Kurzrock R, Law M, McClatchey A, Packer R, Roehm P, Rubenstein A, Slattery W, Tonsgard JH, Welling DB, Widemann B, Yohay K, Giovannini M
published in: Clinical cancer research : an official journal of the American Association for Cancer Research
information resource reference: Consensus recommendations to accelerate clinical trials for neurofibromatosis type 2. Clin Cancer Res. 2009 Aug 15; 15(16):5032-5039.
journal title abbreviation: Clin Cancer Res
publication date: 2009-08-11T00:00:00
year: 2009
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1063366
type: Authorship
author rank in publication: 9
linked author: McClatchey, Andrea
linked information resource: Proliferation-independent role of NF2 (merlin) in limiting biliary morphogenesis.

Proliferation-independent role of NF2 (merlin) in limiting biliary morphogenesis.
PubMed Identifier: 29712669
author list: Benhamouche-Trouillet S, O'Loughlin E, Liu CH, Polacheck W, Fitamant J, McKee M, El-Bardeesy N, Chen CS, McClatchey AI
published in: Development (Cambridge, England)
information resource reference: Proliferation-independent role of NF2 (merlin) in limiting biliary morphogenesis. Development. 2018 04 30; 145(9).
journal title abbreviation: Development
publication date: 2018-04-30T00:00:00
year: 2018
type: Academic Article
type: Article
type: Document
type: Information Resource

Consensus recommendations for current treatments and accelerating clinical trials for patients with neurofibromatosis type 2.
PubMed Identifier: 22140088
author list: Blakeley JO, Evans DG, Adler J, Brackmann D, Chen R, Ferner RE, Hanemann CO, Harris G, Huson SM, Jacob A, Kalamarides M, Karajannis MA, Korf BR, Mautner VF, McClatchey AI, Miao H, Plotkin SR, Slattery W, Stemmer-Rachamimov AO, Welling DB, Wen PY, Widemann B, Hunter-Schaedle K, Giovannini M
published in: American journal of medical genetics. Part A
information resource reference: Consensus recommendations for current treatments and accelerating clinical trials for patients with neurofibromatosis type 2. Am J Med Genet A. 2012 Jan; 158A(1):24-41.
journal title abbreviation: Am J Med Genet A
publication date: 2011-12-02T00:00:00
year: 2011
type: Academic Article
type: Article
type: Document
type: Information Resource

Merlin/ERM proteins establish cortical asymmetry and centrosome position.
PubMed Identifier: 23249734
author list: Hebert AM, DuBoff B, Casaletto JB, Gladden AB, McClatchey AI
published in: Genes & development
information resource reference: Merlin/ERM proteins establish cortical asymmetry and centrosome position. Genes Dev. 2012 Dec 15; 26(24):2709-23.
journal title abbreviation: Genes Dev
publication date: 2012-12-15T00:00:00
year: 2012
type: Academic Article
type: Article
type: Document
type: Information Resource

Mouse models of neurofibromatosis.
PubMed Identifier: 11342186
author list: McClatchey AI, Cichowski K
published in: Biochimica et biophysica acta
information resource reference: Mouse models of neurofibromatosis. Biochim Biophys Acta. 2001; 1471(2):M73-80.
journal title abbreviation: Biochim Biophys Acta
publication date: 2001-01-01T00:00:00
year: 2001
type: Academic Article
type: Article
type: Document
type: Information Resource

Anti-vascular endothelial growth factor therapies as a novel therapeutic approach to treating neurofibromatosis-related tumors.
PubMed Identifier: 20406973
author list: Wong HK, Lahdenranta J, Kamoun WS, Chan AW, McClatchey AI, Plotkin SR, Jain RK, di Tomaso E
published in: Cancer research
information resource reference: Anti-vascular endothelial growth factor therapies as a novel therapeutic approach to treating neurofibromatosis-related tumors. Cancer Res. 2010 May 01; 70(9):3483-93.
journal title abbreviation: Cancer Res
publication date: 2010-04-20T00:00:00
year: 2010
type: Academic Article
type: Article
type: Document
type: Information Resource

Modification of the Na+ current conducted by the rat skeletal muscle alpha subunit by coexpression with a human brain beta subunit.
PubMed Identifier: 7683789
author list: Cannon SC, McClatchey AI, Gusella JF
published in: Pflugers Archiv : European journal of physiology
information resource reference: Modification of the Na+ current conducted by the rat skeletal muscle alpha subunit by coexpression with a human brain beta subunit. Pflugers Arch. 1993 Apr; 423(1-2):155-7.
journal title abbreviation: Pflugers Arch
publication date: 1993-04-01T00:00:00
year: 1993
type: Academic Article
type: Article
type: Document
type: Information Resource

Organizing the cell cortex: the role of ERM proteins.
PubMed Identifier: 20308985
author list: Fehon RG, McClatchey AI, Bretscher A
published in: Nature reviews. Molecular cell biology
information resource reference: Organizing the cell cortex: the role of ERM proteins. Nat Rev Mol Cell Biol. 2010 Apr; 11(4):276-87.
journal title abbreviation: Nat Rev Mol Cell Biol
publication date: 2010-04-01T00:00:00
year: 2010
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 108262
type: Authorship
author rank in publication: 1
linked author: McClatchey, Andrea
linked information resource: Temperature-sensitive mutations in the III-IV cytoplasmic loop region of the skeletal muscle sodium channel gene in paramyotonia congenita.

SPRED proteins provide a NF-ty link to Ras suppression.
PubMed Identifier: 22802525
author list: McClatchey AI, Cichowski K
published in: Genes & development
information resource reference: SPRED proteins provide a NF-ty link to Ras suppression. Genes Dev. 2012 Jul 15; 26(14):1515-9.
journal title abbreviation: Genes Dev
publication date: 2012-07-15T00:00:00
year: 2012
type: Academic Article
type: Article
type: Document
type: Information Resource

Apoptosis and the prognostic significance of p53 mutation.
PubMed Identifier: 7587096
author list: Lowe SW, Bodis S, Bardeesy N, McClatchey A, Remington L, Ruley HE, Fisher DE, Jacks T, Pelletier J, Housman DE
published in: Cold Spring Harbor symposia on quantitative biology
information resource reference: Apoptosis and the prognostic significance of p53 mutation. Cold Spring Harb Symp Quant Biol. 1994; 59:419-26.
journal title abbreviation: Cold Spring Harb Symp Quant Biol
publication date: 1994-01-01T00:00:00
year: 1994
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 115882
type: Authorship
author rank in publication: 12
linked author: McClatchey, Andrea
linked information resource: The Nf2 tumor suppressor, merlin, functions in Rac-dependent signaling.

Authorship 1089249
type: Authorship
author rank in publication: 6
linked author: McClatchey, Andrea
linked information resource: Merlin/ERM proteins regulate growth factor-induced macropinocytosis and receptor recycling by organizing the plasma membrane:cytoskeleton interface.

Merlin/ERM proteins regulate growth factor-induced macropinocytosis and receptor recycling by organizing the plasma membrane:cytoskeleton interface.
PubMed Identifier: 30143526
author list: Chiasson-MacKenzie C, Morris ZS, Liu CH, Bradford WB, Koorman T, McClatchey AI
published in: Genes & development
information resource reference: Merlin/ERM proteins regulate growth factor-induced macropinocytosis and receptor recycling by organizing the plasma membrane:cytoskeleton interface. Genes Dev. 2018 09 01; 32(17-18):1201-1214.
journal title abbreviation: Genes Dev
publication date: 2018-08-24T00:00:00
year: 2018
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 11556
type: Authorship
author rank in publication: 4
linked author: McClatchey, Andrea
linked information resource: The NF2 tumor suppressor, Merlin, regulates epidermal development through the establishment of a junctional polarity complex.

Protease inhibitor domain encoded by an amyloid protein precursor mRNA associated with Alzheimer's disease.
PubMed Identifier: 2893290
author list: Tanzi RE, McClatchey AI, Lamperti ED, Villa-Komaroff L, Gusella JF, Neve RL
published in: Nature
information resource reference: Protease inhibitor domain encoded by an amyloid protein precursor mRNA associated with Alzheimer's disease. Nature. 1988 Feb 11; 331(6156):528-30.
journal title abbreviation: Nature
publication date: 1988-02-11T00:00:00
year: 1988
type: Academic Article
type: Article
type: Document
type: Information Resource

Contact inhibition (of proliferation) redux.
PubMed Identifier: 22835462
author list: McClatchey AI, Yap AS
published in: Current opinion in cell biology
information resource reference: Contact inhibition (of proliferation) redux. Curr Opin Cell Biol. 2012 Oct; 24(5):685-94.
journal title abbreviation: Curr Opin Cell Biol
publication date: 2012-07-24T00:00:00
year: 2012
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 119232
type: Authorship
author rank in publication: 18
linked author: McClatchey, Andrea
linked information resource: Advances in neurofibromatosis 2 (NF2): a workshop report.

ERM proteins.
PubMed Identifier: 23017986
author list: McClatchey AI
published in: Current biology : CB
information resource reference: ERM proteins. Curr Biol. 2012 Sep 25; 22(18):R784-5.
journal title abbreviation: Curr Biol
publication date: 2012-09-25T00:00:00
year: 2012
type: Academic Article
type: Article
type: Document
type: Information Resource

Molecular basis of ornithine aminotransferase deficiency in B-6-responsive and -nonresponsive forms of gyrate atrophy.
PubMed Identifier: 3375240
author list: Ramesh V, McClatchey AI, Ramesh N, Benoit LA, Berson EL, Shih VE, Gusella JF
published in: Proceedings of the National Academy of Sciences of the United States of America
information resource reference: Molecular basis of ornithine aminotransferase deficiency in B-6-responsive and -nonresponsive forms of gyrate atrophy. Proc Natl Acad Sci U S A. 1988 Jun; 85(11):3777-80.
journal title abbreviation: Proc Natl Acad Sci U S A
publication date: 1988-06-01T00:00:00
year: 1988
type: Academic Article
type: Article
type: Document
type: Information Resource

Detection by PCR of the VNTR polymorphism at D4S95.
PubMed Identifier: 1677758
author list: Allitto BA, Horn GT, Altherr MR, Richards B, McClatchey AI, Wasmuth JJ, Gusella JF
published in: Nucleic acids research
information resource reference: Detection by PCR of the VNTR polymorphism at D4S95. Nucleic Acids Res. 1991 Jul 25; 19(14):4015.
journal title abbreviation: Nucleic Acids Res
publication date: 1991-07-25T00:00:00
year: 1991
type: Academic Article
type: Article
type: Document
type: Information Resource

Ezrin...a metastatic detERMinant?
PubMed Identifier: 14998486
author list: Curto M, McClatchey AI
published in: Cancer cell
information resource reference: Ezrin...a metastatic detERMinant? Cancer Cell. 2004 Feb; 5(2):113-4.
journal title abbreviation: Cancer Cell
publication date: 2004-02-01T00:00:00
year: 2004
type: Academic Article
type: Article
type: Document
type: Information Resource

The NF2 tumor suppressor, Merlin, regulates epidermal development through the establishment of a junctional polarity complex.
PubMed Identifier: 21074722
author list: Gladden AB, Hebert AM, Schneeberger EE, McClatchey AI
published in: Developmental cell
information resource reference: The NF2 tumor suppressor, Merlin, regulates epidermal development through the establishment of a junctional polarity complex. Dev Cell. 2010 Nov 16; 19(5):727-39.
journal title abbreviation: Dev Cell
publication date: 2010-11-16T00:00:00
year: 2010
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1119023
type: Authorship
author rank in publication: 1
linked author: McClatchey, Andrea
linked information resource: Actin' Up to Stop SNFin Out TEAD.

Actin' Up to Stop SNFin Out TEAD.
PubMed Identifier: 30562513
author list: McClatchey AI, Georgopoulos K
published in: Developmental cell
information resource reference: Actin' Up to Stop SNFin Out TEAD. Dev Cell. 2018 12 17; 47(6):693-695.
journal title abbreviation: Dev Cell
publication date: 2018-12-17T00:00:00
year: 2018
type: Academic Article
type: Article
type: Document
type: Information Resource

Advances in neurofibromatosis 2 (NF2): a workshop report.
PubMed Identifier: 10992163
author list: Lim DJ, Rubenstein AE, Evans DG, Jacks T, Seizinger BG, Baser ME, Beebe D, Brackmann DE, Chiocca EA, Fehon RG, Giovannini M, Glazer R, Gusella JF, Gutmann DH, Korf B, Lieberman F, Martuza R, McClatchey AI, Parry DM, Pulst SM, Ramesh V, Ramsey WJ, Ratner N, Rutkowski JL, Ruttledge M, Weinstein DE
published in: Journal of neurogenetics
information resource reference: Advances in neurofibromatosis 2 (NF2): a workshop report. J Neurogenet. 2000 Jun; 14(2):63-106.
journal title abbreviation: J Neurogenet
publication date: 2000-06-01T00:00:00
year: 2000
type: Academic Article
type: Article
type: Document
type: Information Resource

DOCK4, a GTPase activator, is disrupted during tumorigenesis.
PubMed Identifier: 12628187
author list: Yajnik V, Paulding C, Sordella R, McClatchey AI, Saito M, Wahrer DC, Reynolds P, Bell DW, Lake R, van den Heuvel S, Settleman J, Haber DA
published in: Cell
information resource reference: DOCK4, a GTPase activator, is disrupted during tumorigenesis. Cell. 2003 Mar 07; 112(5):673-84.
journal title abbreviation: Cell
publication date: 2003-03-07T00:00:00
year: 2003
type: Academic Article
type: Article
type: Document
type: Information Resource

TORC1 is essential for NF1-associated malignancies.
PubMed Identifier: 18164202
author list: Johannessen CM, Johnson BW, Williams SM, Chan AW, Reczek EE, Lynch RC, Rioth MJ, McClatchey A, Ryeom S, Cichowski K
published in: Current biology : CB
information resource reference: TORC1 is essential for NF1-associated malignancies. Curr Biol. 2008 Jan 08; 18(1):56-62.
journal title abbreviation: Curr Biol
publication date: 2007-12-27T00:00:00
year: 2007
type: Academic Article
type: Article
type: Document
type: Information Resource

Neurofibromin 2
MeSH DescriptorUI: D025581
MeSH semantic group name: Chemicals & Drugs
number of authors: 109
number of publications: 300
uniqueness weight: 0.858289
type: Concept

Neurilemmoma
MeSH DescriptorUI: D009442
MeSH semantic group name: Disorders
number of authors: 217
number of publications: 539
uniqueness weight: 0.662512
type: Concept

Cytoskeleton
MeSH DescriptorUI: D003599
MeSH semantic group name: Anatomy
number of authors: 501
number of publications: 1216
uniqueness weight: 0.676042
type: Concept

MGH Cancer Center Research
type: Division
type: Organization

Authorship 112898
type: Authorship
author rank in publication: 5
linked author: McClatchey, Andrea
linked information resource: Contact-dependent inhibition of EGFR signaling by Nf2/Merlin.

Neurofibromatosis 2
MeSH DescriptorUI: D016518
MeSH semantic group name: Disorders
number of authors: 99
number of publications: 389
uniqueness weight: 0.747053
type: Concept

Cytoskeletal Proteins
MeSH DescriptorUI: D003598
MeSH semantic group name: Chemicals & Drugs
number of authors: 633
number of publications: 1348
uniqueness weight: 0.655902
type: Concept

Dermatology
type: Department
type: Organization

Genetics
type: Department
type: Organization

Medicine
type: Department
type: Organization

Neurology
type: Department
type: Organization

Pathology
type: Department
type: Organization

Radiology
type: Department
type: Organization

Systems Biology
type: Department
type: Organization

Genetics
type: Division
type: Organization

Brigham and Women's Hospital
type: Organization

Harvard Medical School
type: Organization

Massachusetts General Hospital
type: Organization

Georgopoulos, Katia
eCommons Login: KG4
first name: Katia
last name: Georgopoulos
full name: Katia Georgopoulos, Ph.D.
has faculty rank: Full Professor
latitude: 42.37730000000000
longitude: -71.05250000000000
Person ID: 64714
person in primary position: Professor of Dermatology
type: Agent
type: Person
preferred title: Professor of Dermatology

selected publications
maximum weight: 1
minimum weight: 1
number of connections: 81
predicate node: https://connects.catalyst.harvard.edu/Profiles/profile/113
predicate: selected publications
type: Network

research areas
maximum weight: 4.52603
minimum weight: 0.000641448
number of connections: 392
predicate node: https://connects.catalyst.harvard.edu/Profiles/profile/217
predicate: research areas
type: Network

coauthor of
maximum weight: 0.662948
minimum weight: 0.0102979
number of connections: 33
predicate node: https://connects.catalyst.harvard.edu/Profiles/profile/363
predicate: coauthor of
type: Network

similar to
maximum weight: 55.5186
minimum weight: 7.15515
number of connections: 60
predicate node: https://connects.catalyst.harvard.edu/Profiles/profile/494
predicate: similar to
type: Network

Ramesh, Vijaya
eCommons Login: VR4
first name: Vijaya
last name: Ramesh
full name: Vijaya Ramesh, Ph.D.
has faculty rank: Full Professor
latitude: 42.36125700000000
longitude: -71.06552700000000
Person ID: 8386
person in primary position: Professor of Neurology
type: Agent
type: Person
preferred title: Professor of Neurology

Jenkins, Bruce
eCommons Login: BGJ1
first name: Bruce
last name: Jenkins
full name: Bruce Gorton Jenkins, Ph.D.
has faculty rank: Instructor
latitude: 42.37730000000000
longitude: -71.05250000000000
Person ID: 51902
person in primary position: Instructor in Radiology
type: Agent
type: Person
preferred title: Instructor in Radiology

Franceschini, Maria
eCommons Login: MAF10
first name: Maria
last name: Franceschini
full name: Maria A. Franceschini, Ph.D.
has faculty rank: Full Professor
latitude: 42.37730000000000
longitude: -71.05250000000000
Person ID: 57008
person in primary position: Professor of Radiology
type: Agent
type: Person
preferred title: Professor of Radiology

Sgroi, Dennis
eCommons Login: DCS3
first name: Dennis
last name: Sgroi
full name: Dennis Charles Sgroi, M.D.
has faculty rank: Full Professor
latitude: 42.37730000000000
longitude: -71.05250000000000
Person ID: 25340
person in primary position: Professor of Pathology
type: Agent
type: Person
preferred title: Professor of Pathology

Stemmer-Rachamimov, Anat
eCommons Login: AS15
first name: Anat
last name: Stemmer-Rachamimov
full name: Anat Stemmer-Rachamimov, M.D.
has faculty rank: Associate Professor
latitude: 42.36241700000000
longitude: -71.06893700000000
Person ID: 5208
person in primary position: Associate Professor of Pathology
type: Agent
type: Person
preferred title: Associate Professor of Pathology

Cichowski, Karen
eCommons Login: KMC8
first name: Karen
last name: Cichowski
full name: Karen Marie Cichowski, Ph.D.
has faculty rank: Full Professor
latitude: 42.33837200000000
longitude: -71.10326900000000
Person ID: 1074
person in primary position: Professor of Medicine
type: Agent
type: Person
preferred title: Professor of Medicine

Mitchison, Timothy
eCommons Login: TJM8
first name: Timothy
last name: Mitchison
full name: Timothy J. Mitchison, Ph.D.
has faculty rank: Full Professor
latitude: 42.33594500000000
longitude: -71.10295800000000
Person ID: 31112
person in primary position: Hasib Sabbagh Professor of Systems Biology
type: Agent
type: Person
preferred title: Hasib Sabbagh Professor of Systems Biology

Rivera, Miguel
eCommons Login: MNR1
first name: Miguel
last name: Rivera
full name: Miguel Nicolas Rivera, M.D.
has faculty rank: Associate Professor
latitude: 42.37730000000000
longitude: -71.05250000000000
Person ID: 60452
person in primary position: Associate Professor of Pathology
type: Agent
type: Person
preferred title: Associate Professor of Pathology

Plotkin, Scott
eCommons Login: SRP5
first name: Scott
last name: Plotkin
full name: Scott Randall Plotkin, M.D.,Ph.D.
has faculty rank: Full Professor
latitude: 42.36241700000000
longitude: -71.06893700000000
photo: https://connects.catalyst.harvard.edu/Profiles/profile/Modules/CustomViewPersonGeneralInfo/PhotoHandler.ashx
Person ID: 57533
person in primary position: Giovanni Armenise - Harvard Professor of Neurology
type: Agent
type: Person
preferred title: Giovanni Armenise - Harvard Professor of Neurology

Stott, Shannon
eCommons Login: SS292
first name: Shannon
last name: Stott
full name: Shannon Stott, Ph.D.
has faculty rank: Associate Professor
latitude: 42.37904200000000
longitude: -71.05148100000000
Person ID: 46870
person in primary position: Associate Professor of Medicine
type: Agent
type: Person
preferred title: Associate Professor of Medicine

MacKenzie, Christine
eCommons Login: CCM21
first name: Christine
last name: MacKenzie
full name: Christine Chiasson MacKenzie, Ph.D.
has faculty rank: Instructor
Person ID: 101120
person in primary position: Instructor in Medicine
type: Agent
type: Person
preferred title: Instructor in Medicine

Perrimon, Norbert
eCommons Login: NP7
first name: Norbert
last name: Perrimon
full name: Norbert Perrimon, Ph.D.
has faculty rank: Full Professor
latitude: 42.33837200000000
longitude: -71.10326900000000
Person ID: 6247
person in primary position: James Stillman Professor of Developmental Biology
type: Agent
type: Person
preferred title: James Stillman Professor of Developmental Biology

Langenau, David
eCommons Login: DML4
first name: David
last name: Langenau
full name: David M. Langenau, Ph.D.
has faculty rank: Full Professor
latitude: 42.37730000000000
longitude: -71.05250000000000
Person ID: 13067
person in primary position: Professor of Pathology
type: Agent
type: Person
preferred title: Professor of Pathology

Gusella, James
eCommons Login: JFG2
first name: James
last name: Gusella
full name: James Francis Gusella, Ph.D.
has faculty rank: Full Professor
latitude: 42.36125700000000
longitude: -71.06552700000000
Person ID: 78528
person in primary position: Bullard Professor of Neurogenetics in the Department of Genetics
type: Agent
type: Person
preferred title: Bullard Professor of Neurogenetics in the Department of Genetics

Professor of Medicine
is primary position: true
position in department: Medicine
position in division: Genetics
sort order: 1
type: Position
HR job title: Professor of Medicine
position in organization: Brigham and Women's Hospital

Associate Professor of Pathology
is primary position: true
position in department: Pathology
position in division: https://connects.catalyst.harvard.edu/Profiles/profile/1229413
sort order: 1
type: Position
HR job title: Associate Professor of Pathology
position in organization: Massachusetts General Hospital

Instructor in Radiology
is primary position: true
position in department: Radiology
position in division: https://connects.catalyst.harvard.edu/Profiles/profile/1229413
sort order: 1
type: Position
HR job title: Instructor in Radiology
position in organization: Massachusetts General Hospital

Professor of Pathology
is primary position: true
position in department: Pathology
position in division: https://connects.catalyst.harvard.edu/Profiles/profile/1229413
sort order: 1
type: Position
HR job title: Professor of Pathology
position in organization: Massachusetts General Hospital

Professor of Radiology
is primary position: true
position in department: Radiology
position in division: https://connects.catalyst.harvard.edu/Profiles/profile/1229413
sort order: 1
type: Position
HR job title: Professor of Radiology
position in organization: Massachusetts General Hospital

Professor of Pathology
is primary position: true
position in department: Pathology
position in division: https://connects.catalyst.harvard.edu/Profiles/profile/1229413
sort order: 1
type: Position
HR job title: Professor of Pathology
position in organization: Massachusetts General Hospital

Giovanni Armenise - Harvard Professor of Neurology
is primary position: true
position in department: Neurology
position in division: https://connects.catalyst.harvard.edu/Profiles/profile/1229413
sort order: 1
type: Position
HR job title: Giovanni Armenise - Harvard Professor of Neurology
position in organization: Massachusetts General Hospital

Authorship 1264989
type: Authorship
author rank in publication: 8
linked author: McClatchey, Andrea
linked information resource: Uncovering mutation-specific morphogenic phenotypes and paracrine-mediated vessel dysfunction in a biomimetic vascularized mammary duct platform.

Uncovering mutation-specific morphogenic phenotypes and paracrine-mediated vessel dysfunction in a biomimetic vascularized mammary duct platform.
PubMed Identifier: 32632100
author list: Kutys ML, Polacheck WJ, Welch MK, Gagnon KA, Koorman T, Kim S, Li L, McClatchey AI, Chen CS
published in: Nature communications
information resource reference: Uncovering mutation-specific morphogenic phenotypes and paracrine-mediated vessel dysfunction in a biomimetic vascularized mammary duct platform. Nat Commun. 2020 07 06; 11(1):3377.
journal title abbreviation: Nat Commun
publication date: 2020-07-06T00:00:00
year: 2020
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 155025
type: Authorship
author rank in publication: 6
linked author: McClatchey, Andrea
linked information resource: Ezrin and moesin function together to promote T cell activation.

Authorship 151530
type: Authorship
author rank in publication: 1
linked author: McClatchey, Andrea
linked information resource: The genomic structure of the human skeletal muscle sodium channel gene.

Authorship 153800
type: Authorship
author rank in publication: 2
linked author: McClatchey, Andrea
linked information resource: Localization and functional domains of the neurofibromatosis type II tumor suppressor, merlin.

Authorship 153810
type: Authorship
author rank in publication: 8
linked author: McClatchey, Andrea
linked information resource: TORC1 is essential for NF1-associated malignancies.

Inside-out construction of the biliary system
end date: 2024-12-31
principal investigator name: MCCLATCHEY, ANDREA I
start date: 2021-01-01
type: Grant
sponsor award id: R01DK127177

Principal Investigator
type: Researcher Role
researcher role of: McClatchey, Andrea
contributes to: Inside-out construction of the biliary system

Authorship 1354544
type: Authorship
author rank in publication: 1
linked author: McClatchey, Andrea
linked information resource: EPHecting cell contact by increasing cortical tension.

EPHecting cell contact by increasing cortical tension.
PubMed Identifier: 33999116
author list: McClatchey AI
published in: The Journal of cell biology
information resource reference: EPHecting cell contact by increasing cortical tension. J Cell Biol. 2021 06 07; 220(6).
journal title abbreviation: J Cell Biol
publication date: 2021-05-17T00:00:00
year: 2021
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 181978
type: Authorship
author rank in publication: 1
linked author: McClatchey, Andrea
linked information resource: SPRED proteins provide a NF-ty link to Ras suppression.

Authorship 197
type: Authorship
author rank in publication: 9
linked author: McClatchey, Andrea
linked information resource: Ezrin is highly expressed in early thymocytes, but dispensable for T cell development in mice.

Authorship 276455
type: Authorship
author rank in publication: 1
linked author: McClatchey, Andrea
linked information resource: Membrane organization and tumorigenesis--the NF2 tumor suppressor, Merlin.

Authorship 281560
type: Authorship
author rank in publication: 8
linked author: McClatchey, Andrea
linked information resource: The genetic defect in familial Alzheimer's disease is not tightly linked to the amyloid beta-protein gene.

Authorship 1534143
type: Authorship
author rank in publication: 8
linked author: McClatchey, Andrea
linked information resource: Cellular mechanisms of heterogeneity in NF2-mutant schwannoma.

Cellular mechanisms of heterogeneity in NF2-mutant schwannoma.
PubMed Identifier: 36944680
author list: Chiasson-MacKenzie C, Vitte J, Liu CH, Wright EA, Flynn EA, Stott SL, Giovannini M, McClatchey AI
published in: Nature communications
information resource reference: Cellular mechanisms of heterogeneity in NF2-mutant schwannoma. Nat Commun. 2023 03 21; 14(1):1559.
journal title abbreviation: Nat Commun
publication date: 2023-03-21T00:00:00
year: 2023
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 253546
type: Authorship
author rank in publication: 4
linked author: McClatchey, Andrea
linked information resource: Ezrin-mediated apical integrity is required for intestinal homeostasis.

Instructor in Medicine
is primary position: true
position in department: Medicine
position in division: MGH Cancer Center Research
sort order: 1
type: Position
HR job title: Instructor in Medicine
position in organization: Massachusetts General Hospital

Professor of Neurology
is primary position: true
position in department: Neurology
position in division: https://connects.catalyst.harvard.edu/Profiles/profile/1229413
sort order: 1
type: Position
HR job title: Professor of Neurology
position in organization: Massachusetts General Hospital

Professor of Pathology
is primary position: true
position in department: Pathology
position in division: https://connects.catalyst.harvard.edu/Profiles/profile/1229413
sort order: 1
type: Position
HR job title: Professor of Pathology
position in organization: Massachusetts General Hospital

Bullard Professor of Neurogenetics in the Department of Genetics
is primary position: true
position in department: Genetics
position in division: https://connects.catalyst.harvard.edu/Profiles/profile/1229413
sort order: 1
type: Position
HR job title: Bullard Professor of Neurogenetics in the Department of Genetics
position in organization: Massachusetts General Hospital

Associate Professor of Medicine
is primary position: true
position in department: Medicine
position in division: MGH Cancer Center Research
sort order: 1
type: Position
HR job title: Associate Professor of Medicine
position in organization: Massachusetts General Hospital

Associate Professor of Pathology
is primary position: true
position in department: Pathology
position in division: https://connects.catalyst.harvard.edu/Profiles/profile/1229413
sort order: 1
type: Position
HR job title: Associate Professor of Pathology
position in organization: Massachusetts General Hospital

Authorship 454645
type: Authorship
author rank in publication: 1
linked author: McClatchey, Andrea
linked information resource: Mice heterozygous for a mutation at the Nf2 tumor suppressor locus develop a range of highly metastatic tumors.

Authorship 31011
type: Authorship
author rank in publication: 2
linked author: McClatchey, Andrea
linked information resource: Nf2/Merlin: a coordinator of receptor signalling and intercellular contact.

Authorship 372883
type: Authorship
author rank in publication: 5
linked author: McClatchey, Andrea
linked information resource: Anti-vascular endothelial growth factor therapies as a novel therapeutic approach to treating neurofibromatosis-related tumors.

Authorship 1700408
type: Authorship
author rank in publication: 12
linked author: McClatchey, Andrea
linked information resource: Distinct phenotypic consequences of cholangiocarcinoma-associated FGFR2 alterations depend on biliary epithelial cell state.

Distinct phenotypic consequences of cholangiocarcinoma-associated FGFR2 alterations depend on biliary epithelial cell state.
PubMed Identifier: 39282270
author list: Chiasson-MacKenzie C, Zhang Y, O'Loughlin E, Dave PS, Menon AS, Westerfield AD, Kumar V, Bhatia SN, Rheinbay E, Bardeesy N, Stott SL, McClatchey AI
published in: bioRxiv : the preprint server for biology
information resource reference: Distinct phenotypic consequences of cholangiocarcinoma-associated FGFR2 alterations depend on biliary epithelial cell state. bioRxiv. 2025 Sep 15.
journal title abbreviation: bioRxiv
publication date: 2025-09-15T00:00:00
year: 2025
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 188173
type: Authorship
author rank in publication: 1
linked author: McClatchey, Andrea
linked information resource: ERM proteins.

Hasib Sabbagh Professor of Systems Biology
is primary position: true
position in department: Systems Biology
position in division: https://connects.catalyst.harvard.edu/Profiles/profile/1229413
sort order: 1
type: Position
HR job title: Hasib Sabbagh Professor of Systems Biology
position in organization: Harvard Medical School

Authorship 212829
type: Authorship
author rank in publication: 1
linked author: McClatchey, Andrea
linked information resource: Contact inhibition (of proliferation) redux.

Authorship 680765
type: Authorship
author rank in publication: 6
linked author: McClatchey, Andrea
linked information resource: Ezrin tunes the magnitude of humoral immunity.

Ezrin tunes the magnitude of humoral immunity.
PubMed Identifier: 24043890
author list: Pore D, Parameswaran N, Matsui K, Stone MB, Saotome I, McClatchey AI, Veatch SL, Gupta N
published in: Journal of immunology (Baltimore, Md. : 1950)
information resource reference: Ezrin tunes the magnitude of humoral immunity. J Immunol. 2013 Oct 15; 191(8):4048-58.
journal title abbreviation: J Immunol
publication date: 2013-09-16T00:00:00
year: 2013
type: Academic Article
type: Article
type: Document
type: Information Resource

James Stillman Professor of Developmental Biology
is primary position: true
position in department: Genetics
position in division: https://connects.catalyst.harvard.edu/Profiles/profile/1229413
sort order: 1
type: Position
HR job title: James Stillman Professor of Developmental Biology
position in organization: Harvard Medical School

Authorship 210917
type: Authorship
author rank in publication: 3
linked author: McClatchey, Andrea
linked information resource: Detection of point mutations associated with genetic diseases by an exon scanning technique.

Authorship 246949
type: Authorship
author rank in publication: 5
linked author: McClatchey, Andrea
linked information resource: Ezrin is key regulator of Src-induced malignant phenotype in three-dimensional environment.

Authorship 397181
type: Authorship
author rank in publication: 1
linked author: McClatchey, Andrea
linked information resource: Neurofibromatosis type II: mouse models reveal broad roles in tumorigenesis and metastasis.

Authorship 403031
type: Authorship
author rank in publication: 1
linked author: McClatchey, Andrea
linked information resource: Mouse models of neurofibromatosis.

Authorship 467289
type: Authorship
author rank in publication: 1
linked author: McClatchey, Andrea
linked information resource: Tumor suppressor mutations in mice: the next generation.

Authorship 714309
type: Authorship
author rank in publication: 25
linked author: McClatchey, Andrea
linked information resource: CTF meeting 2012: Translation of the basic understanding of the biology and genetics of NF1, NF2, and schwannomatosis toward the development of effective therapies.

CTF meeting 2012: Translation of the basic understanding of the biology and genetics of NF1, NF2, and schwannomatosis toward the development of effective therapies.
PubMed Identifier: 24443315
author list: Widemann BC, Acosta MT, Ammoun S, Belzberg AJ, Bernards A, Blakeley J, Bretscher A, Cichowski K, Clapp DW, Dombi E, Evans GD, Ferner R, Fernandez-Valle C, Fisher MJ, Giovannini M, Gutmann DH, Hanemann CO, Hennigan R, Huson S, Ingram D, Kissil J, Korf BR, Legius E, Packer RJ, McClatchey AI, McCormick F, North K, Pehrsson M, Plotkin SR, Ramesh V, Ratner N, Schirmer S, Sherman L, Schorry E, Stevenson D, Stewart DR, Ullrich N, Bakker AC, Morrison H
published in: American journal of medical genetics. Part A
information resource reference: CTF meeting 2012: Translation of the basic understanding of the biology and genetics of NF1, NF2, and schwannomatosis toward the development of effective therapies. Am J Med Genet A. 2014 Mar; 164A(3):563-78.
journal title abbreviation: Am J Med Genet A
publication date: 2014-01-17T00:00:00
year: 2014
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 729160
type: Authorship
author rank in publication: 10
linked author: McClatchey, Andrea
linked information resource: Merlin deficiency predicts FAK inhibitor sensitivity: a synthetic lethal relationship.

Merlin deficiency predicts FAK inhibitor sensitivity: a synthetic lethal relationship.
PubMed Identifier: 24848258
author list: Shapiro IM, Kolev VN, Vidal CM, Kadariya Y, Ring JE, Wright Q, Weaver DT, Menges C, Padval M, McClatchey AI, Xu Q, Testa JR, Pachter JA
published in: Science translational medicine
information resource reference: Merlin deficiency predicts FAK inhibitor sensitivity: a synthetic lethal relationship. Sci Transl Med. 2014 May 21; 6(237):237ra68.
journal title abbreviation: Sci Transl Med
publication date: 2014-05-21T00:00:00
year: 2014
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 283938
type: Authorship
author rank in publication: 1
linked author: McClatchey, Andrea
linked information resource: Splicing defect at the ornithine aminotransferase (OAT) locus in gyrate atrophy.

Professor of Dermatology
is primary position: true
position in department: Dermatology
position in division: Cutaneous Biology Research Center
sort order: 1
type: Position
HR job title: Professor of Dermatology
position in organization: Massachusetts General Hospital

Cutaneous Biology Research Center
type: Division
type: Organization

Authorship 207080
type: Authorship
author rank in publication: 5
linked author: McClatchey, Andrea
linked information resource: Merlin/ERM proteins establish cortical asymmetry and centrosome position.

Authorship 380985
type: Authorship
author rank in publication: 1
linked author: McClatchey, Andrea
linked information resource: Merlin and the ERM proteins--regulators of receptor distribution and signaling at the cell cortex.

Authorship 384704
type: Authorship
author rank in publication: 3
linked author: McClatchey, Andrea
linked information resource: p53 status and the efficacy of cancer therapy in vivo.

Authorship 748036
type: Authorship
author rank in publication: 1
linked author: McClatchey, Andrea
linked information resource: ERM proteins at a glance.

ERM proteins at a glance.
PubMed Identifier: 24951115
author list: McClatchey AI
published in: Journal of cell science
information resource reference: ERM proteins at a glance. J Cell Sci. 2014 Aug 01; 127(Pt 15):3199-204.
journal title abbreviation: J Cell Sci
publication date: 2014-06-20T00:00:00
year: 2014
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 566604
type: Authorship
author rank in publication: 2
linked author: McClatchey, Andrea
linked information resource: Protease inhibitor domain encoded by an amyloid protein precursor mRNA associated with Alzheimer's disease.

Authorship 448957
type: Authorship
author rank in publication: 2
linked author: McClatchey, Andrea
linked information resource: Spatial regulation of receptor tyrosine kinases in development and cancer.

Authorship 769857
type: Authorship
author rank in publication: 13
linked author: McClatchey, Andrea
linked information resource: Update from the 2013 International Neurofibromatosis Conference.

Update from the 2013 International Neurofibromatosis Conference.
PubMed Identifier: 25255738
author list: Plotkin SR, Albers AC, Babovic-Vuksanovic D, Blakeley JO, Breakefield XO, Dunn CM, Evans DG, Fisher MJ, Friedman JM, Giovannini M, Gutmann DH, Kalamarides M, McClatchey AI, Messiaen L, Morrison H, Parkinson DB, Stemmer-Rachamimov AO, Van Raamsdonk CD, Riccardi VM, Rosser T, Schindeler A, Smith MJ, Stevenson DA, Ullrich NJ, van der Vaart T, Weiss B, Widemann BC, Zhu Y, Bakker AC, Lloyd AC
published in: American journal of medical genetics. Part A
information resource reference: Update from the 2013 International Neurofibromatosis Conference. Am J Med Genet A. 2014 Dec; 164A(12):2969-78.
journal title abbreviation: Am J Med Genet A
publication date: 2014-09-24T00:00:00
year: 2014
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 454353
type: Authorship
author rank in publication: 2
linked author: McClatchey, Andrea
linked information resource: Organizing the cell cortex: the role of ERM proteins.

Authorship 510299
type: Authorship
author rank in publication: 12
linked author: McClatchey, Andrea
linked information resource: Expression of the cytoskeleton linker protein ezrin in human cancers.

Authorship 321825
type: Authorship
author rank in publication: 7
linked author: McClatchey, Andrea
linked information resource: A mouse model recapitulating molecular features of human mesothelioma.

Authorship 504591
type: Authorship
author rank in publication: 4
linked author: McClatchey, Andrea
linked information resource: The telomeric 60 kb of chromosome arm 4p is homologous to telomeric regions on 13p, 15p, 21p, and 22p.

Authorship 304949
type: Authorship
author rank in publication: 7
linked author: McClatchey, Andrea
linked information resource: Nf2/Merlin controls progenitor homeostasis and tumorigenesis in the liver.

Authorship 169375
type: Authorship
author rank in publication: 1
linked author: McClatchey, Andrea
linked information resource: The cloning and expression of a sodium channel beta 1-subunit cDNA from human brain.

Authorship 431753
type: Authorship
author rank in publication: 17
linked author: McClatchey, Andrea
linked information resource: Comparative pathology of nerve sheath tumors in mouse models and humans.

Authorship 203984
type: Authorship
author rank in publication: 3
linked author: McClatchey, Andrea
linked information resource: Ezrin is essential for epithelial organization and villus morphogenesis in the developing intestine.

Authorship 380590
type: Authorship
author rank in publication: 4
linked author: McClatchey, Andrea
linked information resource: DOCK4, a GTPase activator, is disrupted during tumorigenesis.

Authorship 23540
type: Authorship
author rank in publication: 2
linked author: McClatchey, Andrea
linked information resource: Molecular basis of ornithine aminotransferase deficiency in B-6-responsive and -nonresponsive forms of gyrate atrophy.

Authorship 448146
type: Authorship
author rank in publication: 5
linked author: McClatchey, Andrea
linked information resource: Detection by PCR of the VNTR polymorphism at D4S95.

Authorship 528735
type: Authorship
author rank in publication: 1
linked author: McClatchey, Andrea
linked information resource: Novel mutations in families with unusual and variable disorders of the skeletal muscle sodium channel.

Authorship 563152
type: Authorship
author rank in publication: 19
linked author: McClatchey, Andrea
linked information resource: Consensus recommendations to accelerate clinical trials for neurofibromatosis type 2.

Authorship 403078
type: Authorship
author rank in publication: 8
linked author: McClatchey, Andrea
linked information resource: Neuropathology of genetically engineered mice: consensus report and recommendations from an international forum.

Authorship 408131
type: Authorship
author rank in publication: 2
linked author: McClatchey, Andrea
linked information resource: Modification of the Na+ current conducted by the rat skeletal muscle alpha subunit by coexpression with a human brain beta subunit.

Authorship 73513
type: Authorship
author rank in publication: 2
linked author: McClatchey, Andrea
linked information resource: Ezrin...a metastatic detERMinant?

Authorship 324338
type: Authorship
author rank in publication: 4
linked author: McClatchey, Andrea
linked information resource: Localization to the cortical cytoskeleton is necessary for Nf2/merlin-dependent epidermal growth factor receptor silencing.

Authorship 304975
type: Authorship
author rank in publication: 2
linked author: McClatchey, Andrea
linked information resource: Aberrant epithelial morphology and persistent epidermal growth factor receptor signaling in a mouse model of renal carcinoma.

Authorship 364956
type: Authorship
author rank in publication: 1
linked author: McClatchey, Andrea
linked information resource: The Nf2 tumor suppressor gene product is essential for extraembryonic development immediately prior to gastrulation.

Authorship 437320
type: Authorship
author rank in publication: 5
linked author: McClatchey, Andrea
linked information resource: NF2 deficiency promotes tumorigenesis and metastasis by destabilizing adherens junctions.

Authorship 467304
type: Authorship
author rank in publication: 2
linked author: McClatchey, Andrea
linked information resource: Assay by polymerase chain reaction (PCR) of multi-allele polymorphisms in the Huntington's disease region of chromosome 4.

Authorship 354323
type: Authorship
author rank in publication: 5
linked author: McClatchey, Andrea
linked information resource: Audiologic and radiographic response of NF2-related vestibular schwannoma to erlotinib therapy.

Authorship 308078
type: Authorship
author rank in publication: 2
linked author: McClatchey, Andrea
linked information resource: Detection by PCR of a VNTR polymorphism at D4S43.

Authorship 501328
type: Authorship
author rank in publication: 8
linked author: McClatchey, Andrea
linked information resource: Mutations in the neutral sphingomyelinase gene SMPD3 implicate the ceramide pathway in human leukemias.

Authorship 842723
type: Authorship
author rank in publication: 11
linked author: McClatchey, Andrea
linked information resource: NF2/Merlin mediates contact-dependent inhibition of EGFR mobility and internalization via cortical actomyosin.

NF2/Merlin mediates contact-dependent inhibition of EGFR mobility and internalization via cortical actomyosin.
PubMed Identifier: 26483553
author list: Chiasson-MacKenzie C, Morris ZS, Baca Q, Morris B, Coker JK, Mirchev R, Jensen AE, Carey T, Stott SL, Golan DE, McClatchey AI
published in: The Journal of cell biology
information resource reference: NF2/Merlin mediates contact-dependent inhibition of EGFR mobility and internalization via cortical actomyosin. J Cell Biol. 2015 Oct 26; 211(2):391-405.
journal title abbreviation: J Cell Biol
publication date: 2015-10-19T00:00:00
year: 2015
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 525676
type: Authorship
author rank in publication: 8
linked author: McClatchey, Andrea
linked information resource: Nf2/merlin regulates hematopoietic stem cell behavior by altering microenvironmental architecture.

Authorship 498034
type: Authorship
author rank in publication: 1
linked author: McClatchey, Andrea
linked information resource: Modeling metastasis in the mouse.

Authorship 61348
type: Authorship
author rank in publication: 15
linked author: McClatchey, Andrea
linked information resource: Consensus recommendations for current treatments and accelerating clinical trials for patients with neurofibromatosis type 2.

Associate Professor
sort order: 1
type: Faculty Rank

Full Professor
sort order: 0
type: Faculty Rank

Instructor
sort order: 4
type: Faculty Rank

Authorship 68514
type: Authorship
author rank in publication: 4
linked author: McClatchey, Andrea
linked information resource: Apoptosis and the prognostic significance of p53 mutation.

Functional analysis of ERM proteins in epithelial morphogenesis
end date: 2014-12-31
principal investigator name: FEHON, RICHARD G
start date: 2010-01-01
type: Grant
sponsor award id: R01GM087558

Dana-Farber/Harvard Cancer Center
end date: 2027-11-30
principal investigator name: EBERT, BENJAMIN LEVINE
start date: 1900-01-01
type: Grant
sponsor award id: P30CA006516

Molecular Function of the Nf2 Tumor Suppressor, Merlin
end date: 2016-05-31
principal investigator name: MCCLATCHEY, ANDREA I
start date: 2005-08-01
type: Grant
sponsor award id: R01CA113733

Principal Investigator
type: Researcher Role
researcher role of: McClatchey, Andrea
contributes to: Molecular Function of the Nf2 Tumor Suppressor, Merlin

Co-Principal Investigator
type: Researcher Role
researcher role of: McClatchey, Andrea
contributes to: Functional analysis of ERM proteins in epithelial morphogenesis

Co-Principal Investigator
type: Researcher Role
researcher role of: McClatchey, Andrea
contributes to: Dana-Farber/Harvard Cancer Center

Authorship 320462
type: Authorship
author rank in publication: 2
linked author: McClatchey, Andrea
linked information resource: The neurofibroma cell of origin: SKPs expand the playing field.

Authorship 44532
type: Authorship
author rank in publication: 1
linked author: McClatchey, Andrea
linked information resource: Merlin and ERM proteins: unappreciated roles in cancer development?

Authorship 459747
type: Authorship
author rank in publication: 1
linked author: McClatchey, Andrea
linked information resource: Neurofibromatosis.

Authorship 277858
type: Authorship
author rank in publication: 1
linked author: McClatchey, Andrea
linked information resource: Dinucleotide repeat polymorphisms at the SCN4A locus suggest allelic heterogeneity of hyperkalemic periodic paralysis and paramyotonia congenita.

Authorship 422573
type: Authorship
author rank in publication: 2
linked author: McClatchey, Andrea
linked information resource: Regulation of the neurofibromatosis type 2 tumor suppressor protein, merlin, by adhesion and growth arrest stimuli.

Authorship 562383
type: Authorship
author rank in publication: 4
linked author: McClatchey, Andrea
linked information resource: Microvilli defects in retinas of ezrin knockout mice.

Modeling metastasis in the mouse.
PubMed Identifier: 10498886
author list: McClatchey AI
published in: Oncogene
information resource reference: Modeling metastasis in the mouse. Oncogene. 1999 Sep 20; 18(38):5334-9.
journal title abbreviation: Oncogene
publication date: 1999-09-20T00:00:00
year: 1999
type: Academic Article
type: Article
type: Document
type: Information Resource

Comparative pathology of nerve sheath tumors in mouse models and humans.
PubMed Identifier: 15150133
author list: Stemmer-Rachamimov AO, Louis DN, Nielsen GP, Antonescu CR, Borowsky AD, Bronson RT, Burns DK, Cervera P, McLaughlin ME, Reifenberger G, Schmale MC, MacCollin M, Chao RC, Cichowski K, Kalamarides M, Messerli SM, McClatchey AI, Niwa-Kawakita M, Ratner N, Reilly KM, Zhu Y, Giovannini M
published in: Cancer research
information resource reference: Comparative pathology of nerve sheath tumors in mouse models and humans. Cancer Res. 2004 May 15; 64(10):3718-24.
journal title abbreviation: Cancer Res
publication date: 2004-05-15T00:00:00
year: 2004
type: Academic Article
type: Article
type: Document
type: Information Resource

Novel mutations in families with unusual and variable disorders of the skeletal muscle sodium channel.
PubMed Identifier: 1338909
author list: McClatchey AI, McKenna-Yasek D, Cros D, Worthen HG, Kuncl RW, DeSilva SM, Cornblath DR, Gusella JF, Brown RH
published in: Nature genetics
information resource reference: Novel mutations in families with unusual and variable disorders of the skeletal muscle sodium channel. Nat Genet. 1992 Oct; 2(2):148-52.
journal title abbreviation: Nat Genet
publication date: 1992-10-01T00:00:00
year: 1992
type: Academic Article
type: Article
type: Document
type: Information Resource

Neurofibromatosis type II: mouse models reveal broad roles in tumorigenesis and metastasis.
PubMed Identifier: 10840384
author list: McClatchey AI
published in: Molecular medicine today
information resource reference: Neurofibromatosis type II: mouse models reveal broad roles in tumorigenesis and metastasis. Mol Med Today. 2000 Jun; 6(6):252-3.
journal title abbreviation: Mol Med Today
publication date: 2000-06-01T00:00:00
year: 2000
type: Academic Article
type: Article
type: Document
type: Information Resource

NF2 deficiency promotes tumorigenesis and metastasis by destabilizing adherens junctions.
PubMed Identifier: 12695331
author list: Lallemand D, Curto M, Saotome I, Giovannini M, McClatchey AI
published in: Genes & development
information resource reference: NF2 deficiency promotes tumorigenesis and metastasis by destabilizing adherens junctions. Genes Dev. 2003 May 01; 17(9):1090-100.
journal title abbreviation: Genes Dev
publication date: 2003-04-14T00:00:00
year: 2003
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 963421
type: Authorship
author rank in publication: 18
linked author: McClatchey, Andrea
linked information resource: YAP Inhibition Restores Hepatocyte Differentiation in Advanced HCC, Leading to Tumor Regression.

YAP Inhibition Restores Hepatocyte Differentiation in Advanced HCC, Leading to Tumor Regression.
PubMed Identifier: 25772357
author list: Fitamant J, Kottakis F, Benhamouche S, Tian HS, Chuvin N, Parachoniak CA, Nagle JM, Perera RM, Lapouge M, Deshpande V, Zhu AX, Lai A, Min B, Hoshida Y, Avruch J, Sia D, Campreciós G, McClatchey AI, Llovet JM, Morrissey D, Raj L, Bardeesy N
published in: Cell reports
information resource reference: YAP Inhibition Restores Hepatocyte Differentiation in Advanced HCC, Leading to Tumor Regression. Cell Rep. 2015 Mar 17; 10(10):1692-1707.
journal title abbreviation: Cell Rep
publication date: 2015-03-12T00:00:00
year: 2015
type: Academic Article
type: Article
type: Document
type: Information Resource

Sequence-tagged sites (STSs) spanning 4p16.3 and the Huntington disease candidate region.
PubMed Identifier: 1533609
author list: Gusella JF, Altherr MR, McClatchey AI, Doucette-Stamm LA, Tagle D, Plummer S, Groot N, Barnes G, Hummerich H, Collins FS
published in: Genomics
information resource reference: Sequence-tagged sites (STSs) spanning 4p16.3 and the Huntington disease candidate region. Genomics. 1992 May; 13(1):75-80.
journal title abbreviation: Genomics
publication date: 1992-05-01T00:00:00
year: 1992
type: Academic Article
type: Article
type: Document
type: Information Resource

A mouse model recapitulating molecular features of human mesothelioma.
PubMed Identifier: 16166281
author list: Altomare DA, Vaslet CA, Skele KL, De Rienzo A, Devarajan K, Jhanwar SC, McClatchey AI, Kane AB, Testa JR
published in: Cancer research
information resource reference: A mouse model recapitulating molecular features of human mesothelioma. Cancer Res. 2005 Sep 15; 65(18):8090-5.
journal title abbreviation: Cancer Res
publication date: 2005-09-15T00:00:00
year: 2005
type: Academic Article
type: Article
type: Document
type: Information Resource

Microvilli defects in retinas of ezrin knockout mice.
PubMed Identifier: 16289046
author list: Bonilha VL, Rayborn ME, Saotome I, McClatchey AI, Hollyfield JG
published in: Experimental eye research
information resource reference: Microvilli defects in retinas of ezrin knockout mice. Exp Eye Res. 2006 Apr; 82(4):720-9.
journal title abbreviation: Exp Eye Res
publication date: 2005-11-10T00:00:00
year: 2005
type: Academic Article
type: Article
type: Document
type: Information Resource

Dinucleotide repeat polymorphisms at the SCN4A locus suggest allelic heterogeneity of hyperkalemic periodic paralysis and paramyotonia congenita.
PubMed Identifier: 1315122
author list: McClatchey AI, Trofatter J, McKenna-Yasek D, Raskind W, Bird T, Pericak-Vance M, Gilchrist J, Arahata K, Radosavljevic D, Worthen HG
published in: American journal of human genetics
information resource reference: Dinucleotide repeat polymorphisms at the SCN4A locus suggest allelic heterogeneity of hyperkalemic periodic paralysis and paramyotonia congenita. Am J Hum Genet. 1992 May; 50(5):896-901.
journal title abbreviation: Am J Hum Genet
publication date: 1992-05-01T00:00:00
year: 1992
type: Academic Article
type: Article
type: Document
type: Information Resource

Mice heterozygous for a mutation at the Nf2 tumor suppressor locus develop a range of highly metastatic tumors.
PubMed Identifier: 9553042
author list: McClatchey AI, Saotome I, Mercer K, Crowley D, Gusella JF, Bronson RT, Jacks T
published in: Genes & development
information resource reference: Mice heterozygous for a mutation at the Nf2 tumor suppressor locus develop a range of highly metastatic tumors. Genes Dev. 1998 Apr 15; 12(8):1121-33.
journal title abbreviation: Genes Dev
publication date: 1998-04-15T00:00:00
year: 1998
type: Academic Article
type: Article
type: Document
type: Information Resource

Spatial regulation of receptor tyrosine kinases in development and cancer.
PubMed Identifier: 22622641
author list: Casaletto JB, McClatchey AI
published in: Nature reviews. Cancer
information resource reference: Spatial regulation of receptor tyrosine kinases in development and cancer. Nat Rev Cancer. 2012 May 24; 12(6):387-400.
journal title abbreviation: Nat Rev Cancer
publication date: 2012-05-24T00:00:00
year: 2012
type: Academic Article
type: Article
type: Document
type: Information Resource

Detection by PCR of a VNTR polymorphism at D4S43.
PubMed Identifier: 1679922
author list: Horn GT, McClatchey AI, Richards B, MacDonald ME, Gusella JF
published in: Nucleic acids research
information resource reference: Detection by PCR of a VNTR polymorphism at D4S43. Nucleic Acids Res. 1991 Sep 11; 19(17):4772.
journal title abbreviation: Nucleic Acids Res
publication date: 1991-09-11T00:00:00
year: 1991
type: Academic Article
type: Article
type: Document
type: Information Resource

Neuropathology of genetically engineered mice: consensus report and recommendations from an international forum.
PubMed Identifier: 12386807
author list: Weiss WA, Israel M, Cobbs C, Holland E, James CD, Louis DN, Marks C, McClatchey AI, Roberts T, Van Dyke T, Wetmore C, Chiu IM, Giovannini M, Guha A, Higgins RJ, Marino S, Radovanovic I, Reilly K, Aldape K
published in: Oncogene
information resource reference: Neuropathology of genetically engineered mice: consensus report and recommendations from an international forum. Oncogene. 2002 Oct 24; 21(49):7453-63.
journal title abbreviation: Oncogene
publication date: 2002-10-24T00:00:00
year: 2002
type: Academic Article
type: Article
type: Document
type: Information Resource

Merlin and ERM proteins: unappreciated roles in cancer development?
PubMed Identifier: 14668818
author list: McClatchey AI
published in: Nature reviews. Cancer
information resource reference: Merlin and ERM proteins: unappreciated roles in cancer development? Nat Rev Cancer. 2003 11; 3(11):877-83.
journal title abbreviation: Nat Rev Cancer
publication date: 2003-11-01T00:00:00
year: 2003
type: Academic Article
type: Article
type: Document
type: Information Resource

The genomic structure of the human skeletal muscle sodium channel gene.
PubMed Identifier: 1339144
author list: McClatchey AI, Lin CS, Wang J, Hoffman EP, Rojas C, Gusella JF
published in: Human molecular genetics
information resource reference: The genomic structure of the human skeletal muscle sodium channel gene. Hum Mol Genet. 1992 Oct; 1(7):521-7.
journal title abbreviation: Hum Mol Genet
publication date: 1992-10-01T00:00:00
year: 1992
type: Academic Article
type: Article
type: Document
type: Information Resource

Expression of the cytoskeleton linker protein ezrin in human cancers.
PubMed Identifier: 17370041
author list: Bruce B, Khanna G, Ren L, Landberg G, Jirström K, Powell C, Borczuk A, Keller ET, Wojno KJ, Meltzer P, Baird K, McClatchey A, Bretscher A, Hewitt SM, Khanna C
published in: Clinical & experimental metastasis
information resource reference: Expression of the cytoskeleton linker protein ezrin in human cancers. Clin Exp Metastasis. 2007; 24(2):69-78.
journal title abbreviation: Clin Exp Metastasis
publication date: 2007-03-17T00:00:00
year: 2007
type: Academic Article
type: Article
type: Document
type: Information Resource

149 13th Street
type: Address
address line 1: Massachusetts General Hospital
address line 2: MGH Cancer Center
address line 3: 149 13th Street
city: Charlestown
postal code: 02129
state or province: MA

Detection of point mutations associated with genetic diseases by an exon scanning technique.
PubMed Identifier: 2276738
author list: Kaufman DL, Ramesh V, McClatchey AI, Menkes JH, Tobin AJ
published in: Genomics
information resource reference: Detection of point mutations associated with genetic diseases by an exon scanning technique. Genomics. 1990 Dec; 8(4):656-63.
journal title abbreviation: Genomics
publication date: 1990-12-01T00:00:00
year: 1990
type: Academic Article
type: Article
type: Document
type: Information Resource

Regulation of the neurofibromatosis type 2 tumor suppressor protein, merlin, by adhesion and growth arrest stimuli.
PubMed Identifier: 9516485
author list: Shaw RJ, McClatchey AI, Jacks T
published in: The Journal of biological chemistry
information resource reference: Regulation of the neurofibromatosis type 2 tumor suppressor protein, merlin, by adhesion and growth arrest stimuli. J Biol Chem. 1998 Mar 27; 273(13):7757-64.
journal title abbreviation: J Biol Chem
publication date: 1998-03-27T00:00:00
year: 1998
type: Academic Article
type: Article
type: Document
type: Information Resource

Tumor suppressor mutations in mice: the next generation.
PubMed Identifier: 9690995
author list: McClatchey AI, Jacks T
published in: Current opinion in genetics & development
information resource reference: Tumor suppressor mutations in mice: the next generation. Curr Opin Genet Dev. 1998 Jun; 8(3):304-10.
journal title abbreviation: Curr Opin Genet Dev
publication date: 1998-06-01T00:00:00
year: 1998
type: Academic Article
type: Article
type: Document
type: Information Resource

Neurofibromatosis.
PubMed Identifier: 18039098
author list: McClatchey AI
published in: Annual review of pathology
information resource reference: Neurofibromatosis. Annu Rev Pathol. 2007; 2:191-216.
journal title abbreviation: Annu Rev Pathol
publication date: 2007-01-01T00:00:00
year: 2007
type: Academic Article
type: Article
type: Document
type: Information Resource

Mutations in the neutral sphingomyelinase gene SMPD3 implicate the ceramide pathway in human leukemias.
PubMed Identifier: 18299447
author list: Kim WJ, Okimoto RA, Purton LE, Goodwin M, Haserlat SM, Dayyani F, Sweetser DA, McClatchey AI, Bernard OA, Look AT, Bell DW, Scadden DT, Haber DA
published in: Blood
information resource reference: Mutations in the neutral sphingomyelinase gene SMPD3 implicate the ceramide pathway in human leukemias. Blood. 2008 May 01; 111(9):4716-22.
journal title abbreviation: Blood
publication date: 2008-02-25T00:00:00
year: 2008
type: Academic Article
type: Article
type: Document
type: Information Resource

p53 status and the efficacy of cancer therapy in vivo.
PubMed Identifier: 7973635
author list: Lowe SW, Bodis S, McClatchey A, Remington L, Ruley HE, Fisher DE, Housman DE, Jacks T
published in: Science (New York, N.Y.)
information resource reference: p53 status and the efficacy of cancer therapy in vivo. Science. 1994 Nov 04; 266(5186):807-10.
journal title abbreviation: Science
publication date: 1994-11-04T00:00:00
year: 1994
type: Academic Article
type: Article
type: Document
type: Information Resource

The Nf2 tumor suppressor gene product is essential for extraembryonic development immediately prior to gastrulation.
PubMed Identifier: 9171370
author list: McClatchey AI, Saotome I, Ramesh V, Gusella JF, Jacks T
published in: Genes & development
information resource reference: The Nf2 tumor suppressor gene product is essential for extraembryonic development immediately prior to gastrulation. Genes Dev. 1997 May 15; 11(10):1253-65.
journal title abbreviation: Genes Dev
publication date: 1997-05-15T00:00:00
year: 1997
type: Academic Article
type: Article
type: Document
type: Information Resource

Localization and functional domains of the neurofibromatosis type II tumor suppressor, merlin.
PubMed Identifier: 9563848
author list: Shaw RJ, McClatchey AI, Jacks T
published in: Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research
information resource reference: Localization and functional domains of the neurofibromatosis type II tumor suppressor, merlin. Cell Growth Differ. 1998 Apr; 9(4):287-96.
journal title abbreviation: Cell Growth Differ
publication date: 1998-04-01T00:00:00
year: 1998
type: Academic Article
type: Article
type: Document
type: Information Resource

Nf2/Merlin: a coordinator of receptor signalling and intercellular contact.
PubMed Identifier: 17971776
author list: Curto M, McClatchey AI
published in: British journal of cancer
information resource reference: Nf2/Merlin: a coordinator of receptor signalling and intercellular contact. Br J Cancer. 2008 Jan 29; 98(2):256-62.
journal title abbreviation: Br J Cancer
publication date: 2007-10-30T00:00:00
year: 2007
type: Academic Article
type: Article
type: Document
type: Information Resource

Aberrant epithelial morphology and persistent epidermal growth factor receptor signaling in a mouse model of renal carcinoma.
PubMed Identifier: 19487675
author list: Morris ZS, McClatchey AI
published in: Proceedings of the National Academy of Sciences of the United States of America
information resource reference: Aberrant epithelial morphology and persistent epidermal growth factor receptor signaling in a mouse model of renal carcinoma. Proc Natl Acad Sci U S A. 2009 Jun 16; 106(24):9767-72.
journal title abbreviation: Proc Natl Acad Sci U S A
publication date: 2009-06-01T00:00:00
year: 2009
type: Academic Article
type: Article
type: Document
type: Information Resource

Ezrin is key regulator of Src-induced malignant phenotype in three-dimensional environment.
PubMed Identifier: 21666723
author list: Heiska L, Melikova M, Zhao F, Saotome I, McClatchey AI, Carpén O
published in: Oncogene
information resource reference: Ezrin is key regulator of Src-induced malignant phenotype in three-dimensional environment. Oncogene. 2011 Dec 15; 30(50):4953-62.
journal title abbreviation: Oncogene
publication date: 2011-06-13T00:00:00
year: 2011
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1006937
type: Authorship
author rank in publication: 2
linked author: McClatchey, Andrea
linked information resource: Cell-Cell Contact and Receptor Tyrosine Kinase Signaling.

Cell-Cell Contact and Receptor Tyrosine Kinase Signaling.
PubMed Identifier: 28716887
author list: Chiasson-MacKenzie C, McClatchey AI
published in: Cold Spring Harbor perspectives in biology
information resource reference: Cell-Cell Contact and Receptor Tyrosine Kinase Signaling. Cold Spring Harb Perspect Biol. 2018 06 01; 10(6).
journal title abbreviation: Cold Spring Harb Perspect Biol
publication date: 2018-06-01T00:00:00
year: 2018
type: Academic Article
type: Article
type: Document
type: Information Resource

2017 Cell Contact and Adhesion Gordon Research Conference and Gordon Research Seminar
end date: 2018-04-30
principal investigator name: MCCLATCHEY, ANDREA I
start date: 2017-05-01
type: Grant
sponsor award id: R13CA216892

Principal Investigator
type: Researcher Role
researcher role of: McClatchey, Andrea
contributes to: 2017 Cell Contact and Adhesion Gordon Research Conference and Gordon Research Seminar

Ezrin-mediated apical integrity is required for intestinal homeostasis.
PubMed Identifier: 21730140
author list: Casaletto JB, Saotome I, Curto M, McClatchey AI
published in: Proceedings of the National Academy of Sciences of the United States of America
information resource reference: Ezrin-mediated apical integrity is required for intestinal homeostasis. Proc Natl Acad Sci U S A. 2011 Jul 19; 108(29):11924-9.
journal title abbreviation: Proc Natl Acad Sci U S A
publication date: 2011-07-05T00:00:00
year: 2011
type: Academic Article
type: Article
type: Document
type: Information Resource

The telomeric 60 kb of chromosome arm 4p is homologous to telomeric regions on 13p, 15p, 21p, and 22p.
PubMed Identifier: 1427851
author list: Youngman S, Bates GP, Williams S, McClatchey AI, Baxendale S, Sedlacek Z, Altherr M, Wasmuth JJ, MacDonald ME, Gusella JF
published in: Genomics
information resource reference: The telomeric 60 kb of chromosome arm 4p is homologous to telomeric regions on 13p, 15p, 21p, and 22p. Genomics. 1992 Oct; 14(2):350-6.
journal title abbreviation: Genomics
publication date: 1992-10-01T00:00:00
year: 1992
type: Academic Article
type: Article
type: Document
type: Information Resource

Membrane organization and tumorigenesis--the NF2 tumor suppressor, Merlin.
PubMed Identifier: 16204178
author list: McClatchey AI, Giovannini M
published in: Genes & development
information resource reference: Membrane organization and tumorigenesis--the NF2 tumor suppressor, Merlin. Genes Dev. 2005 Oct 01; 19(19):2265-77.
journal title abbreviation: Genes Dev
publication date: 2005-10-01T00:00:00
year: 2005
type: Academic Article
type: Article
type: Document
type: Information Resource

Ezrin and moesin function together to promote T cell activation.
PubMed Identifier: 19124745
author list: Shaffer MH, Dupree RS, Zhu P, Saotome I, Schmidt RF, McClatchey AI, Freedman BD, Burkhardt JK
published in: Journal of immunology (Baltimore, Md. : 1950)
information resource reference: Ezrin and moesin function together to promote T cell activation. J Immunol. 2009 Jan 15; 182(2):1021-32.
journal title abbreviation: J Immunol
publication date: 2009-01-15T00:00:00
year: 2009
type: Academic Article
type: Article
type: Document
type: Information Resource

Nf2/Merlin controls progenitor homeostasis and tumorigenesis in the liver.
PubMed Identifier: 20675406
author list: Benhamouche S, Curto M, Saotome I, Gladden AB, Liu CH, Giovannini M, McClatchey AI
published in: Genes & development
information resource reference: Nf2/Merlin controls progenitor homeostasis and tumorigenesis in the liver. Genes Dev. 2010 Aug 15; 24(16):1718-30.
journal title abbreviation: Genes Dev
publication date: 2010-07-30T00:00:00
year: 2010
type: Academic Article
type: Article
type: Document
type: Information Resource

Ezrin is essential for epithelial organization and villus morphogenesis in the developing intestine.
PubMed Identifier: 15177033
author list: Saotome I, Curto M, McClatchey AI
published in: Developmental cell
information resource reference: Ezrin is essential for epithelial organization and villus morphogenesis in the developing intestine. Dev Cell. 2004 Jun; 6(6):855-64.
journal title abbreviation: Dev Cell
publication date: 2004-06-01T00:00:00
year: 2004
type: Academic Article
type: Article
type: Document
type: Information Resource

Audiologic and radiographic response of NF2-related vestibular schwannoma to erlotinib therapy.
PubMed Identifier: 18560388
author list: Plotkin SR, Singh MA, O'Donnell CC, Harris GJ, McClatchey AI, Halpin C
published in: Nature clinical practice. Oncology
information resource reference: Audiologic and radiographic response of NF2-related vestibular schwannoma to erlotinib therapy. Nat Clin Pract Oncol. 2008 Aug; 5(8):487-91.
journal title abbreviation: Nat Clin Pract Oncol
publication date: 2008-06-17T00:00:00
year: 2008
type: Academic Article
type: Article
type: Document
type: Information Resource

Nf2/merlin regulates hematopoietic stem cell behavior by altering microenvironmental architecture.
PubMed Identifier: 18682243
author list: Larsson J, Ohishi M, Garrison B, Aspling M, Janzen V, Adams GB, Curto M, McClatchey AI, Schipani E, Scadden DT
published in: Cell stem cell
information resource reference: Nf2/merlin regulates hematopoietic stem cell behavior by altering microenvironmental architecture. Cell Stem Cell. 2008 Aug 07; 3(2):221-7.
journal title abbreviation: Cell Stem Cell
publication date: 2008-08-07T00:00:00
year: 2008
type: Academic Article
type: Article
type: Document
type: Information Resource

Contact-dependent inhibition of EGFR signaling by Nf2/Merlin.
PubMed Identifier: 17548515
author list: Curto M, Cole BK, Lallemand D, Liu CH, McClatchey AI
published in: The Journal of cell biology
information resource reference: Contact-dependent inhibition of EGFR signaling by Nf2/Merlin. J Cell Biol. 2007 Jun 04; 177(5):893-903.
journal title abbreviation: J Cell Biol
publication date: 2007-06-04T00:00:00
year: 2007
type: Academic Article
type: Article
type: Document
type: Information Resource

Splicing defect at the ornithine aminotransferase (OAT) locus in gyrate atrophy.
PubMed Identifier: 2220818
author list: McClatchey AI, Kaufman DL, Berson EL, Tobin AJ, Shih VE, Gusella JF, Ramesh V
published in: American journal of human genetics
information resource reference: Splicing defect at the ornithine aminotransferase (OAT) locus in gyrate atrophy. Am J Hum Genet. 1990 Nov; 47(5):790-4.
journal title abbreviation: Am J Hum Genet
publication date: 1990-11-01T00:00:00
year: 1990
type: Academic Article
type: Article
type: Document
type: Information Resource

Merlin and the ERM proteins--regulators of receptor distribution and signaling at the cell cortex.
PubMed Identifier: 19345106
author list: McClatchey AI, Fehon RG
published in: Trends in cell biology
information resource reference: Merlin and the ERM proteins--regulators of receptor distribution and signaling at the cell cortex. Trends Cell Biol. 2009 May; 19(5):198-206.
journal title abbreviation: Trends Cell Biol
publication date: 2009-04-01T00:00:00
year: 2009
type: Academic Article
type: Article
type: Document
type: Information Resource

Localization to the cortical cytoskeleton is necessary for Nf2/merlin-dependent epidermal growth factor receptor silencing.
PubMed Identifier: 18086884
author list: Cole BK, Curto M, Chan AW, McClatchey AI
published in: Molecular and cellular biology
information resource reference: Localization to the cortical cytoskeleton is necessary for Nf2/merlin-dependent epidermal growth factor receptor silencing. Mol Cell Biol. 2008 Feb; 28(4):1274-84.
journal title abbreviation: Mol Cell Biol
publication date: 2007-12-17T00:00:00
year: 2007
type: Academic Article
type: Article
type: Document
type: Information Resource

The neurofibroma cell of origin: SKPs expand the playing field.
PubMed Identifier: 19427284
author list: Morris ZS, McClatchey AI
published in: Cell stem cell
information resource reference: The neurofibroma cell of origin: SKPs expand the playing field. Cell Stem Cell. 2009 May 08; 4(5):371-2.
journal title abbreviation: Cell Stem Cell
publication date: 2009-05-08T00:00:00
year: 2009
type: Academic Article
type: Article
type: Document
type: Information Resource

The genetic defect in familial Alzheimer's disease is not tightly linked to the amyloid beta-protein gene.
PubMed Identifier: 2888020
author list: Tanzi RE, St George-Hyslop PH, Haines JL, Polinsky RJ, Nee L, Foncin JF, Neve RL, McClatchey AI, Conneally PM, Gusella JF
published in: Nature
information resource reference: The genetic defect in familial Alzheimer's disease is not tightly linked to the amyloid beta-protein gene. Nature. 1987 Sep 10-16; 329(6135):156-7.
journal title abbreviation: Nature
publication date: 1987-09-01T00:00:00
year: 1987
type: Academic Article
type: Article
type: Document
type: Information Resource

The cloning and expression of a sodium channel beta 1-subunit cDNA from human brain.
PubMed Identifier: 8394762
author list: McClatchey AI, Cannon SC, Slaugenhaupt SA, Gusella JF
published in: Human molecular genetics
information resource reference: The cloning and expression of a sodium channel beta 1-subunit cDNA from human brain. Hum Mol Genet. 1993 Jun; 2(6):745-9.
journal title abbreviation: Hum Mol Genet
publication date: 1993-06-01T00:00:00
year: 1993
type: Academic Article
type: Article
type: Document
type: Information Resource

Ezrin is highly expressed in early thymocytes, but dispensable for T cell development in mice.
PubMed Identifier: 20806059
author list: Shaffer MH, Huang Y, Corbo E, Wu GF, Velez M, Choi JK, Saotome I, Cannon JL, McClatchey AI, Sperling AI, Maltzman JS, Oliver PM, Bhandoola A, Laufer TM, Burkhardt JK
published in: PloS one
information resource reference: Ezrin is highly expressed in early thymocytes, but dispensable for T cell development in mice. PLoS One. 2010 Aug 27; 5(8):e12404.
journal title abbreviation: PLoS One
publication date: 2010-08-27T00:00:00
year: 2010
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1043188
type: Authorship
author rank in publication: 2
linked author: McClatchey, Andrea
linked information resource: EGFR-induced cytoskeletal changes drive complex cell behaviors: The tip of the iceberg.

EGFR-induced cytoskeletal changes drive complex cell behaviors: The tip of the iceberg.
PubMed Identifier: 29382786
author list: Chiasson-MacKenzie C, McClatchey AI
published in: Science signaling
information resource reference: EGFR-induced cytoskeletal changes drive complex cell behaviors: The tip of the iceberg. Sci Signal. 2018 01 30; 11(515).
journal title abbreviation: Sci Signal
publication date: 2018-01-30T00:00:00
year: 2018
type: Academic Article
type: Article
type: Document
type: Information Resource

Temperature-sensitive mutations in the III-IV cytoplasmic loop region of the skeletal muscle sodium channel gene in paramyotonia congenita.
PubMed Identifier: 1310898
author list: McClatchey AI, Van den Bergh P, Pericak-Vance MA, Raskind W, Verellen C, McKenna-Yasek D, Rao K, Haines JL, Bird T, Brown RH
published in: Cell
information resource reference: Temperature-sensitive mutations in the III-IV cytoplasmic loop region of the skeletal muscle sodium channel gene in paramyotonia congenita. Cell. 1992 Feb 21; 68(4):769-74.
journal title abbreviation: Cell
publication date: 1992-02-21T00:00:00
year: 1992
type: Academic Article
type: Article
type: Document
type: Information Resource

Assay by polymerase chain reaction (PCR) of multi-allele polymorphisms in the Huntington's disease region of chromosome 4.
PubMed Identifier: 1480191
author list: Allitto BA, McClatchey AI, Barnes G, Altherr M, Wasmuth J, Frischauf AM, MacDonald ME, Gusella J
published in: Molecular and cellular probes
information resource reference: Assay by polymerase chain reaction (PCR) of multi-allele polymorphisms in the Huntington's disease region of chromosome 4. Mol Cell Probes. 1992 Dec; 6(6):513-20.
journal title abbreviation: Mol Cell Probes
publication date: 1992-12-01T00:00:00
year: 1992
type: Academic Article
type: Article
type: Document
type: Information Resource

The Nf2 tumor suppressor, merlin, functions in Rac-dependent signaling.
PubMed Identifier: 11703924
author list: Shaw RJ, Paez JG, Curto M, Yaktine A, Pruitt WM, Saotome I, O'Bryan JP, Gupta V, Ratner N, Der CJ, Jacks T, McClatchey AI
published in: Developmental cell
information resource reference: The Nf2 tumor suppressor, merlin, functions in Rac-dependent signaling. Dev Cell. 2001 Jul; 1(1):63-72.
journal title abbreviation: Dev Cell
publication date: 2001-07-01T00:00:00
year: 2001
type: Academic Article
type: Article
type: Document
type: Information Resource