Hughes, Michael
eCommons Login: MDH6
first name: Michael
last name: Hughes
coauthor of: Shapiro, Roger
coauthor of: Li, Jonathan
coauthor of: Giganti, Mark
coauthor of: Lockman, Shahin
coauthor of: Powis, Kathleen
full name: Michael David Hughes, Ph.D.
has faculty rank: Full Professor
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photo: https://connects.catalyst.harvard.edu/Profiles/profile/Modules/CustomViewPersonGeneralInfo/PhotoHandler.ashx
Person ID: 13310
person in primary position: Professor of Biostatistics
physical neighbor: Betensky, Rebecca
physical neighbor: Dominici, Francesca
physical neighbor: Huttenhower, Curtis
physical neighbor: Laird, Nan
physical neighbor: Pagano, Marcello
similar to: Mayer, Kenneth
similar to: Sax, Paul
similar to: Kuritzkes, Daniel
similar to: Fawzi, Wafaie
similar to: Haberer, Jessica
type: Agent
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selected publications: Authorship 1816661
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Authorship 1045246
type: Authorship
author rank in publication: 8
linked author: Hughes, Michael
linked information resource: Lower pre-ART intra-participant HIV-1 pol diversity may not be associated with virologic failure in adults.

Lower pre-ART intra-participant HIV-1 pol diversity may not be associated with virologic failure in adults.
PubMed Identifier: 29370196
author list: Kearney MF, Spindler J, Wiegand A, Shao W, Haubrich R, Riddler S, Lalama CM, Hughes MD, Coffin JM, Mellors JW
published in: PloS one
information resource reference: Lower pre-ART intra-participant HIV-1 pol diversity may not be associated with virologic failure in adults. PLoS One. 2018; 13(1):e0190438.
journal title abbreviation: PLoS One
publication date: 2018-01-25T00:00:00
year: 2018
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 100849
type: Authorship
author rank in publication: 2
linked author: Hughes, Michael
linked information resource: https://connects.catalyst.harvard.edu/Profiles/profile/748678

Evaluating surrogate endpoints.
PubMed Identifier: 12505247
author list: Hughes MD
published in: Controlled clinical trials
information resource reference: Evaluating surrogate endpoints. Control Clin Trials. 2002 Dec; 23(6):703-7.
journal title abbreviation: Control Clin Trials
publication date: 2002-12-01T00:00:00
year: 2002
type: Academic Article
type: Article
type: Document
type: Information Resource

Pharmacokinetics of saquinavir plus low-dose ritonavir in human immunodeficiency virus-infected pregnant women.
PubMed Identifier: 14742191
author list: Acosta EP, Bardeguez A, Zorrilla CD, Van Dyke R, Hughes MD, Huang S, Pompeo L, Stek AM, Pitt J, Watts DH, Smith E, Jiménez E, Mofenson L
published in: Antimicrobial agents and chemotherapy
information resource reference: Pharmacokinetics of saquinavir plus low-dose ritonavir in human immunodeficiency virus-infected pregnant women. Antimicrob Agents Chemother. 2004 Feb; 48(2):430-6.
journal title abbreviation: Antimicrob Agents Chemother
publication date: 2004-02-01T00:00:00
year: 2004
type: Academic Article
type: Article
type: Document
type: Information Resource

Early initiation of lopinavir/ritonavir in infants less than 6 weeks of age: pharmacokinetics and 24-week safety and efficacy.
PubMed Identifier: 19209098
author list: Chadwick EG, Pinto J, Yogev R, Alvero CG, Hughes MD, Palumbo P, Robbins B, Hazra R, Serchuck L, Heckman BE, Purdue L, Browning R, Luzuriaga K, Rodman J, Capparelli E
published in: The Pediatric infectious disease journal
information resource reference: Early initiation of lopinavir/ritonavir in infants less than 6 weeks of age: pharmacokinetics and 24-week safety and efficacy. Pediatr Infect Dis J. 2009 Mar; 28(3):215-9.
journal title abbreviation: Pediatr Infect Dis J
publication date: 2009-03-01T00:00:00
year: 2009
type: Academic Article
type: Article
type: Document
type: Information Resource

The role of social networks and support in postpartum women's depression: a multiethnic urban sample.
PubMed Identifier: 16404681
author list: Surkan PJ, Peterson KE, Hughes MD, Gottlieb BR
published in: Maternal and child health journal
information resource reference: The role of social networks and support in postpartum women's depression: a multiethnic urban sample. Matern Child Health J. 2006 Jul; 10(4):375-83.
journal title abbreviation: Matern Child Health J
publication date: 2006-07-01T00:00:00
year: 2006
type: Academic Article
type: Article
type: Document
type: Information Resource

Stopping guidelines for clinical trials with multiple treatments.
PubMed Identifier: 8337547
author list: Hughes MD
published in: Statistics in medicine
information resource reference: Stopping guidelines for clinical trials with multiple treatments. Stat Med. 1993 May 30; 12(10):901-15.
journal title abbreviation: Stat Med
publication date: 1993-05-30T00:00:00
year: 1993
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 103967
type: Authorship
author rank in publication: 7
linked author: Hughes, Michael
linked information resource: Lymphoma diagnosis and plasma Epstein-Barr virus load during vicriviroc therapy: results of the AIDS Clinical Trials Group A5211.

Treatment-mediated changes in human immunodeficiency virus (HIV) type 1 RNA and CD4 cell counts as predictors of weight growth failure, cognitive decline, and survival in HIV-infected children.
PubMed Identifier: 11010839
author list: Lindsey JC, Hughes MD, McKinney RE, Cowles MK, Englund JA, Baker CJ, Burchett SK, Kline MW, Kovacs A, Moye J
published in: The Journal of infectious diseases
information resource reference: Treatment-mediated changes in human immunodeficiency virus (HIV) type 1 RNA and CD4 cell counts as predictors of weight growth failure, cognitive decline, and survival in HIV-infected children. J Infect Dis. 2000 Nov; 182(5):1385-93.
journal title abbreviation: J Infect Dis
publication date: 2000-09-22T00:00:00
year: 2000
type: Academic Article
type: Article
type: Document
type: Information Resource

Differences between women and men in adverse events and CD4+ responses to nucleoside analogue therapy for HIV infection. The Aids Clinical Trials Group 175 Team.
PubMed Identifier: 11015147
author list: Currier JS, Spino C, Grimes J, Wofsy CB, Katzenstein DA, Hughes MD, Hammer SM, Cotton DJ
published in: Journal of acquired immune deficiency syndromes (1999)
information resource reference: Differences between women and men in adverse events and CD4+ responses to nucleoside analogue therapy for HIV infection. The Aids Clinical Trials Group 175 Team. J Acquir Immune Defic Syndr. 2000 Aug 01; 24(4):316-24.
journal title abbreviation: J Acquir Immune Defic Syndr
publication date: 2000-08-01T00:00:00
year: 2000
type: Academic Article
type: Article
type: Document
type: Information Resource

Neurodevelopmental functioning in HIV-infected infants and young children before and after the introduction of protease inhibitor-based highly active antiretroviral therapy.
PubMed Identifier: 17296781
author list: Lindsey JC, Malee KM, Brouwers P, Hughes MD
published in: Pediatrics
information resource reference: Neurodevelopmental functioning in HIV-infected infants and young children before and after the introduction of protease inhibitor-based highly active antiretroviral therapy. Pediatrics. 2007 Mar; 119(3):e681-93.
journal title abbreviation: Pediatrics
publication date: 2007-02-12T00:00:00
year: 2007
type: Academic Article
type: Article
type: Document
type: Information Resource

A prospective, randomized trial of clear liquids versus low-fat solid diet as the initial meal in mild acute pancreatitis.
PubMed Identifier: 17613280
author list: Jacobson BC, Vander Vliet MB, Hughes MD, Maurer R, McManus K, Banks PA
published in: Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association
information resource reference: A prospective, randomized trial of clear liquids versus low-fat solid diet as the initial meal in mild acute pancreatitis. Clin Gastroenterol Hepatol. 2007 Aug; 5(8):946-51; quiz 886.
journal title abbreviation: Clin Gastroenterol Hepatol
publication date: 2007-07-05T00:00:00
year: 2007
type: Academic Article
type: Article
type: Document
type: Information Resource

Risk factors for detectable HIV-1 RNA at delivery among women receiving highly active antiretroviral therapy in the women and infants transmission study.
PubMed Identifier: 20065861
author list: Katz IT, Shapiro R, Li D, Govindarajulu U, Thompson B, Watts DH, Hughes MD, Tuomala R
published in: Journal of acquired immune deficiency syndromes (1999)
information resource reference: Risk factors for detectable HIV-1 RNA at delivery among women receiving highly active antiretroviral therapy in the women and infants transmission study. J Acquir Immune Defic Syndr. 2010 May 01; 54(1):27-34.
journal title abbreviation: J Acquir Immune Defic Syndr
publication date: 2010-05-01T00:00:00
year: 2010
type: Academic Article
type: Article
type: Document
type: Information Resource

Insulin-like growth factor-1 and lean body mass in HIV-infected children.
PubMed Identifier: 18614924
author list: Chantry CJ, Hughes MD, Alvero C, Cervia JS, Hodge J, Borum P, Moye J
published in: Journal of acquired immune deficiency syndromes (1999)
information resource reference: Insulin-like growth factor-1 and lean body mass in HIV-infected children. J Acquir Immune Defic Syndr. 2008 Aug 01; 48(4):437-43.
journal title abbreviation: J Acquir Immune Defic Syndr
publication date: 2008-08-01T00:00:00
year: 2008
type: Academic Article
type: Article
type: Document
type: Information Resource

Response to vicriviroc in treatment-experienced subjects, as determined by an enhanced-sensitivity coreceptor tropism assay: reanalysis of AIDS clinical trials group A5211.
PubMed Identifier: 19874179
author list: Su Z, Gulick RM, Krambrink A, Coakley E, Hughes MD, Han D, Flexner C, Wilkin TJ, Skolnik PR, Greaves WL, Kuritzkes DR, Reeves JD
published in: The Journal of infectious diseases
information resource reference: Response to vicriviroc in treatment-experienced subjects, as determined by an enhanced-sensitivity coreceptor tropism assay: reanalysis of AIDS clinical trials group A5211. J Infect Dis. 2009 Dec 01; 200(11):1724-8.
journal title abbreviation: J Infect Dis
publication date: 2009-12-01T00:00:00
year: 2009
type: Academic Article
type: Article
type: Document
type: Information Resource

Stability of autistic traits in the general population: further evidence for a continuum of impairment.
PubMed Identifier: 21421177
author list: Robinson EB, Munir K, Munafò MR, Hughes M, McCormick MC, Koenen KC
published in: Journal of the American Academy of Child and Adolescent Psychiatry
information resource reference: Stability of autistic traits in the general population: further evidence for a continuum of impairment. J Am Acad Child Adolesc Psychiatry. 2011 Apr; 50(4):376-84.
journal title abbreviation: J Am Acad Child Adolesc Psychiatry
publication date: 2011-02-25T00:00:00
year: 2011
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1062335
type: Authorship
author rank in publication: 4
linked author: Hughes, Michael
linked information resource: Similar HIV protection from four weeks of zidovudine versus nevirapine prophylaxis among formula-fed infants in Botswana.

Similar HIV protection from four weeks of zidovudine versus nevirapine prophylaxis among formula-fed infants in Botswana.
PubMed Identifier: 29707385
author list: Powis KM, Lockman S, Ajibola G, Hughes MD, Bennett K, Leidner J, Batlang O, Botebele K, Moyo S, van Widenfelt E, Makhema J, Petlo C, Jibril HB, McIntosh K, Essex M, Shapiro RL
published in: Southern African journal of HIV medicine
information resource reference: Similar HIV protection from four weeks of zidovudine versus nevirapine prophylaxis among formula-fed infants in Botswana. South Afr J HIV Med. 2018; 19(1):751.
journal title abbreviation: South Afr J HIV Med
publication date: 2018-03-28T00:00:00
year: 2018
type: Academic Article
type: Article
type: Document
type: Information Resource

Regression dilution in the proportional hazards model.
PubMed Identifier: 8117900
author list: Hughes MD
published in: Biometrics
information resource reference: Regression dilution in the proportional hazards model. Biometrics. 1993 Dec; 49(4):1056-66.
journal title abbreviation: Biometrics
publication date: 1993-12-01T00:00:00
year: 1993
type: Academic Article
type: Article
type: Document
type: Information Resource

Oxidant stress and peripheral neuropathy during antiretroviral therapy: an AIDS clinical trials group study.
PubMed Identifier: 16791116
author list: Hulgan T, Hughes M, Sun X, Smeaton LM, Terry E, Robbins GK, Shafer RW, Clifford DB, McComsey GA, Canter JA, Morrow JD, Haas DW
published in: Journal of acquired immune deficiency syndromes (1999)
information resource reference: Oxidant stress and peripheral neuropathy during antiretroviral therapy: an AIDS clinical trials group study. J Acquir Immune Defic Syndr. 2006 Aug 01; 42(4):450-4.
journal title abbreviation: J Acquir Immune Defic Syndr
publication date: 2006-08-01T00:00:00
year: 2006
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1064388
type: Authorship
author rank in publication: 6
linked author: Hughes, Michael
linked information resource: Effects of sofosbuvir-based hepatitis C treatment on the pharmacokinetics of tenofovir in HIV/HCV-coinfected individuals receiving tenofovir disoproxil fumarate.

Effects of sofosbuvir-based hepatitis C treatment on the pharmacokinetics of tenofovir in HIV/HCV-coinfected individuals receiving tenofovir disoproxil fumarate.
PubMed Identifier: 29746648
author list: MacBrayne CE, Marks KM, Fierer DS, Naggie S, Chung RT, Hughes MD, Kim AY, Peters MG, Brainard DM, Seifert SM, Castillo-Mancilla JR, Bushman LR, Anderson PL, Kiser JJ
published in: The Journal of antimicrobial chemotherapy
information resource reference: Effects of sofosbuvir-based hepatitis C treatment on the pharmacokinetics of tenofovir in HIV/HCV-coinfected individuals receiving tenofovir disoproxil fumarate. J Antimicrob Chemother. 2018 08 01; 73(8):2112-2119.
journal title abbreviation: J Antimicrob Chemother
publication date: 2018-08-01T00:00:00
year: 2018
type: Academic Article
type: Article
type: Document
type: Information Resource

HIV type 1 chemokine coreceptor use among antiretroviral-experienced patients screened for a clinical trial of a CCR5 inhibitor: AIDS Clinical Trial Group A5211.
PubMed Identifier: 17243065
author list: Wilkin TJ, Su Z, Kuritzkes DR, Hughes M, Flexner C, Gross R, Coakley E, Greaves W, Godfrey C, Skolnik PR, Timpone J, Rodriguez B, Gulick RM
published in: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
information resource reference: HIV type 1 chemokine coreceptor use among antiretroviral-experienced patients screened for a clinical trial of a CCR5 inhibitor: AIDS Clinical Trial Group A5211. Clin Infect Dis. 2007 Feb 15; 44(4):591-5.
journal title abbreviation: Clin Infect Dis
publication date: 2007-01-17T00:00:00
year: 2007
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1070316
type: Authorship
author rank in publication: 5
linked author: Hughes, Michael
linked information resource: Targeted HIV testing at birth supported by low and predictable mother-to-child transmission risk in Botswana.

Targeted HIV testing at birth supported by low and predictable mother-to-child transmission risk in Botswana.
PubMed Identifier: 29852062
author list: Ibrahim M, Maswabi K, Ajibola G, Moyo S, Hughes MD, Batlang O, Sakoi M, Auletta-Young C, Vaughan L, Lockman S, Jean-Philippe P, Yu X, Lichterfeld M, Kuritzkes DR, Makhema J, Shapiro RL
published in: Journal of the International AIDS Society
information resource reference: Targeted HIV testing at birth supported by low and predictable mother-to-child transmission risk in Botswana. J Int AIDS Soc. 2018 05; 21(5):e25111.
journal title abbreviation: J Int AIDS Soc
publication date: 2018-05-01T00:00:00
year: 2018
type: Academic Article
type: Article
type: Document
type: Information Resource

Detection of replication-competent human immunodeficiency virus type 1 (HIV-1) in cultures from patients with levels of HIV-1 RNA in plasma suppressed to less than 500 or 50 copies per milliliter.
PubMed Identifier: 12037070
author list: Demeter LM, Bosch RJ, Coombs RW, Fiscus S, Bremer J, Johnson VA, Erice A, Jackson JB, Spector SA, Squires KM, Fischl MA, Hughes MD, Hammer SM
published in: Journal of clinical microbiology
information resource reference: Detection of replication-competent human immunodeficiency virus type 1 (HIV-1) in cultures from patients with levels of HIV-1 RNA in plasma suppressed to less than 500 or 50 copies per milliliter. J Clin Microbiol. 2002 Jun; 40(6):2089-94.
journal title abbreviation: J Clin Microbiol
publication date: 2002-06-01T00:00:00
year: 2002
type: Academic Article
type: Article
type: Document
type: Information Resource

Can fluid resuscitation prevent pancreatic necrosis in severe acute pancreatitis?
PubMed Identifier: 12123089
author list: Brown A, Baillargeon JD, Hughes MD, Banks PA
published in: Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.]
information resource reference: Can fluid resuscitation prevent pancreatic necrosis in severe acute pancreatitis? Pancreatology. 2002; 2(2):104-7.
journal title abbreviation: Pancreatology
publication date: 2002-01-01T00:00:00
year: 2002
type: Academic Article
type: Article
type: Document
type: Information Resource

Evaluating surrogate markers.
PubMed Identifier: 7552506
author list: Hughes MD, DeGruttola V, Welles SL
published in: Journal of acquired immune deficiency syndromes and human retrovirology : official publication of the International Retrovirology Association
information resource reference: Evaluating surrogate markers. J Acquir Immune Defic Syndr Hum Retrovirol. 1995; 10 Suppl 2:S1-8.
journal title abbreviation: J Acquir Immune Defic Syndr Hum Retrovirol
publication date: 1995-01-01T00:00:00
year: 1995
type: Academic Article
type: Article
type: Document
type: Information Resource

Stopping rules and estimation problems in clinical trials.
PubMed Identifier: 3231947
author list: Hughes MD, Pocock SJ
published in: Statistics in medicine
information resource reference: Stopping rules and estimation problems in clinical trials. Stat Med. 1988 Dec; 7(12):1231-42.
journal title abbreviation: Stat Med
publication date: 1988-12-01T00:00:00
year: 1988
type: Academic Article
type: Article
type: Document
type: Information Resource

Statistical problems in the reporting of clinical trials. A survey of three medical journals.
PubMed Identifier: 3614286
author list: Pocock SJ, Hughes MD, Lee RJ
published in: The New England journal of medicine
information resource reference: Statistical problems in the reporting of clinical trials. A survey of three medical journals. N Engl J Med. 1987 Aug 13; 317(7):426-32.
journal title abbreviation: N Engl J Med
publication date: 1987-08-13T00:00:00
year: 1987
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 106687
type: Authorship
author rank in publication: 4
linked author: Hughes, Michael
linked information resource: Impact of protease inhibitor-containing combination antiretroviral therapies on height and weight growth in HIV-infected children.

Antiretroviral therapies in women after single-dose nevirapine exposure.
PubMed Identifier: 20942666
author list: Lockman S, Hughes MD, McIntyre J, Zheng Y, Chipato T, Conradie F, Sawe F, Asmelash A, Hosseinipour MC, Mohapi L, Stringer E, Mngqibisa R, Siika A, Atwine D, Hakim J, Shaffer D, Kanyama C, Wools-Kaloustian K, Salata RA, Hogg E, Alston-Smith B, Walawander A, Purcelle-Smith E, Eshleman S, Rooney J, Rahim S, Mellors JW, Schooley RT, Currier JS
published in: The New England journal of medicine
information resource reference: Antiretroviral therapies in women after single-dose nevirapine exposure. N Engl J Med. 2010 Oct 14; 363(16):1499-509.
journal title abbreviation: N Engl J Med
publication date: 2010-10-14T00:00:00
year: 2010
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1080927
type: Authorship
author rank in publication: 2
linked author: Hughes, Michael
linked information resource: A Challenging Case of Fibromuscular Dysplasia in a Transgender Patient: Is There a Hormonal Link?

A Challenging Case of Fibromuscular Dysplasia in a Transgender Patient: Is There a Hormonal Link?
PubMed Identifier: 29988870
author list: Shalan A, Hughes M, Nicholls M, Thompson A
published in: EJVES short reports
information resource reference: A Challenging Case of Fibromuscular Dysplasia in a Transgender Patient: Is There a Hormonal Link? EJVES Short Rep. 2018; 39:16-19.
journal title abbreviation: EJVES Short Rep
publication date: 2018-05-08T00:00:00
year: 2018
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 116035
type: Authorship
author rank in publication: 1
linked author: Hughes, Michael
linked information resource: CD4 cell count as a surrogate endpoint in HIV clinical trials: a meta-analysis of studies of the AIDS Clinical Trials Group.

Authorship 1087020
type: Authorship
author rank in publication: 4
linked author: Hughes, Michael
linked information resource: Resource utilization for multidrug-resistant tuberculosis household contact investigations (A5300/I2003).

Resource utilization for multidrug-resistant tuberculosis household contact investigations (A5300/I2003).
PubMed Identifier: 30092866
author list: Swindells S, Gupta A, Kim S, Hughes MD, Sanchez J, Mave V, Dawson R, Kumarasamy N, Comins K, Smith B, Rustomjee R, Naini L, Shah NS, Hesseling A, Churchyard G
published in: The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease
information resource reference: Resource utilization for multidrug-resistant tuberculosis household contact investigations (A5300/I2003). Int J Tuberc Lung Dis. 2018 09 01; 22(9):1016-1022.
journal title abbreviation: Int J Tuberc Lung Dis
publication date: 2018-09-01T00:00:00
year: 2018
type: Academic Article
type: Article
type: Document
type: Information Resource

Role of low-frequency HIV-1 variants in failure of nevirapine-containing antiviral therapy in women previously exposed to single-dose nevirapine.
PubMed Identifier: 21576473
author list: Boltz VF, Zheng Y, Lockman S, Hong F, Halvas EK, McIntyre J, Currier JS, Chibowa MC, Kanyama C, Nair A, Owino-Ong'or W, Hughes M, Coffin JM, Mellors JW
published in: Proceedings of the National Academy of Sciences of the United States of America
information resource reference: Role of low-frequency HIV-1 variants in failure of nevirapine-containing antiviral therapy in women previously exposed to single-dose nevirapine. Proc Natl Acad Sci U S A. 2011 May 31; 108(22):9202-7.
journal title abbreviation: Proc Natl Acad Sci U S A
publication date: 2011-05-16T00:00:00
year: 2011
type: Academic Article
type: Article
type: Document
type: Information Resource

https://connects.catalyst.harvard.edu/Profiles/profile/1099186
PubMed Identifier: 8633815
author list: D'Aquila RT, Hughes MD, Johnson VA, Fischl MA, Sommadossi JP, Liou SH, Timpone J, Myers M, Basgoz N, Niu M, Hirsch MS
published in: Annals of internal medicine
information resource reference: Nevirapine, zidovudine, and didanosine compared with zidovudine and didanosine in patients with HIV-1 infection. A randomized, double-blind, placebo-controlled trial. National Institute of Allergy and Infectious Diseases AIDS Clinical Trials Group Protocol 241 Investigators. Ann Intern Med. 1996 Jun 15; 124(12):1019-30.
journal title abbreviation: Ann Intern Med
publication date: 1996-06-15T00:00:00
year: 1996
type: Academic Article
type: Article
type: Document
type: Information Resource
label: Nevirapine, zidovudine, and didanosine compared with zidovudine and didanosine in patients with HIV-1 infection. A randomized, double-blind, placebo-controlled trial. National Institute of Allergy and Infectious Diseases AIDS Clinical Trials Group Protocol 241 Investigators.

Authorship 1094453
type: Authorship
author rank in publication: 1
linked author: Hughes, Michael
linked information resource: Exploring the patient experience of digital ulcers in systemic sclerosis.

Exploring the patient experience of digital ulcers in systemic sclerosis.
PubMed Identifier: 30205981
author list: Hughes M, Pauling JD
published in: Seminars in arthritis and rheumatism
information resource reference: Exploring the patient experience of digital ulcers in systemic sclerosis. Semin Arthritis Rheum. 2019 04; 48(5):888-894.
journal title abbreviation: Semin Arthritis Rheum
publication date: 2018-08-11T00:00:00
year: 2018
type: Academic Article
type: Article
type: Document
type: Information Resource

Giganti, Mark
eCommons Login: MJG38
first name: Mark
last name: Giganti
full name: Mark Giganti, Ph.D.
has faculty rank: Other Faculty
Person ID: 173214
person in primary position: Senior Research Scientist
type: Agent
type: Person
preferred title: Senior Research Scientist

Extensive diversity of Ig-superfamily proteins in the immune system of insects.
PubMed Identifier: 16109846
author list: Watson FL, Püttmann-Holgado R, Thomas F, Lamar DL, Hughes M, Kondo M, Rebel VI, Schmucker D
published in: Science (New York, N.Y.)
information resource reference: Extensive diversity of Ig-superfamily proteins in the immune system of insects. Science. 2005 Sep 16; 309(5742):1874-8.
journal title abbreviation: Science
publication date: 2005-08-18T00:00:00
year: 2005
type: Academic Article
type: Article
type: Document
type: Information Resource

Accelerated wound healing: multidisciplinary advances in the care of venous leg ulcers.
PubMed Identifier: 16518520
author list: Bongiovanni CM, Hughes MD, Bomengen RW
published in: Angiology
information resource reference: Accelerated wound healing: multidisciplinary advances in the care of venous leg ulcers. Angiology. 2006 Mar-Apr; 57(2):139-44.
journal title abbreviation: Angiology
publication date: 2006-03-01T00:00:00
year: 2006
type: Academic Article
type: Article
type: Document
type: Information Resource

https://connects.catalyst.harvard.edu/Profiles/profile/1115920
PubMed Identifier: 17646352
author list: McKinney RE, Rodman J, Hu C, Britto P, Hughes M, Smith ME, Serchuck LK, Kraimer J, Ortiz AA, Flynn P, Yogev R, Spector S, Draper L, Tran P, Scites M, Dickover R, Weinberg A, Cunningham C, Abrams E, Blum MR, Chittick GE, Reynolds L, Rathore M
published in: Pediatrics
information resource reference: Long-term safety and efficacy of a once-daily regimen of emtricitabine, didanosine, and efavirenz in HIV-infected, therapy-naive children and adolescents: Pediatric AIDS Clinical Trials Group Protocol P1021. Pediatrics. 2007 Aug; 120(2):e416-23.
journal title abbreviation: Pediatrics
publication date: 2007-07-23T00:00:00
year: 2007
type: Academic Article
type: Article
type: Document
type: Information Resource
label: Long-term safety and efficacy of a once-daily regimen of emtricitabine, didanosine, and efavirenz in HIV-infected, therapy-naive children and adolescents: Pediatric AIDS Clinical Trials Group Protocol P1021.

Lymphoma diagnosis and plasma Epstein-Barr virus load during vicriviroc therapy: results of the AIDS Clinical Trials Group A5211.
PubMed Identifier: 19191652
author list: Tsibris AM, Paredes R, Chadburn A, Su Z, Henrich TJ, Krambrink A, Hughes MD, Aberg JA, Currier JS, Tashima K, Godfrey C, Greaves W, Flexner C, Skolnik PR, Wilkin TJ, Gulick RM, Kuritzkes DR
published in: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
information resource reference: Lymphoma diagnosis and plasma Epstein-Barr virus load during vicriviroc therapy: results of the AIDS Clinical Trials Group A5211. Clin Infect Dis. 2009 Mar 01; 48(5):642-9.
journal title abbreviation: Clin Infect Dis
publication date: 2009-03-01T00:00:00
year: 2009
type: Academic Article
type: Article
type: Document
type: Information Resource

The impact of psoriasis on pregnancy outcomes.
PubMed Identifier: 21918537
author list: Lima XT, Janakiraman V, Hughes MD, Kimball AB
published in: The Journal of investigative dermatology
information resource reference: The impact of psoriasis on pregnancy outcomes. J Invest Dermatol. 2012 Jan; 132(1):85-91.
journal title abbreviation: J Invest Dermatol
publication date: 2011-09-15T00:00:00
year: 2011
type: Academic Article
type: Article
type: Document
type: Information Resource

Delayed onset of pubertal development in children and adolescents with perinatally acquired HIV infection.
PubMed Identifier: 12792356
author list: Buchacz K, Rogol AD, Lindsey JC, Wilson CM, Hughes MD, Seage GR, Oleske JM, Rogers AS
published in: Journal of acquired immune deficiency syndromes (1999)
information resource reference: Delayed onset of pubertal development in children and adolescents with perinatally acquired HIV infection. J Acquir Immune Defic Syndr. 2003 May 01; 33(1):56-65.
journal title abbreviation: J Acquir Immune Defic Syndr
publication date: 2003-05-01T00:00:00
year: 2003
type: Academic Article
type: Article
type: Document
type: Information Resource

Lack of protective effects of interleukin-4 -589-C/T polymorphism against HIV-1-related disease progression and central nervous system impairment, in children.
PubMed Identifier: 14767810
author list: Singh KK, Hughes MD, Chen J, Spector SA
published in: The Journal of infectious diseases
information resource reference: Lack of protective effects of interleukin-4 -589-C/T polymorphism against HIV-1-related disease progression and central nervous system impairment, in children. J Infect Dis. 2004 Feb 15; 189(4):587-92.
journal title abbreviation: J Infect Dis
publication date: 2004-01-29T00:00:00
year: 2004
type: Academic Article
type: Article
type: Document
type: Information Resource

The search for data on when to start treatment for HIV infection.
PubMed Identifier: 18462158
author list: Hughes MD, Ribaudo HR
published in: The Journal of infectious diseases
information resource reference: The search for data on when to start treatment for HIV infection. J Infect Dis. 2008 Apr 15; 197(8):1084-6.
journal title abbreviation: J Infect Dis
publication date: 2008-04-15T00:00:00
year: 2008
type: Academic Article
type: Article
type: Document
type: Information Resource

Randomized controlled trial of feeding a concentrated formula to infants born to women infected by human immunodeficiency virus.
PubMed Identifier: 19543114
author list: Winter HS, Oleske JM, Hughes MD, McKinney RE, Elgie C, Powell C, Purdue L, Puga AM, Jimenez E, Scott GB, Cruz ML, Moye J
published in: Journal of pediatric gastroenterology and nutrition
information resource reference: Randomized controlled trial of feeding a concentrated formula to infants born to women infected by human immunodeficiency virus. J Pediatr Gastroenterol Nutr. 2009 Aug; 49(2):222-32.
journal title abbreviation: J Pediatr Gastroenterol Nutr
publication date: 2009-08-01T00:00:00
year: 2009
type: Academic Article
type: Article
type: Document
type: Information Resource

Assessing the effects of interventions using longitudinal data with samples subject to selection.
PubMed Identifier: 9290223
author list: Lin HM, Hughes MD
published in: Biometrics
information resource reference: Assessing the effects of interventions using longitudinal data with samples subject to selection. Biometrics. 1997 Sep; 53(3):924-36.
journal title abbreviation: Biometrics
publication date: 1997-09-01T00:00:00
year: 1997
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1122854
type: Authorship
author rank in publication: 3
linked author: Hughes, Michael
linked information resource: HIV testing uptake among the household contacts of multidrug-resistant tuberculosis index cases in eight countries.

HIV testing uptake among the household contacts of multidrug-resistant tuberculosis index cases in eight countries.
PubMed Identifier: 30606316
author list: Opollo VS, Wu X, Hughes MD, Swindells S, Gupta A, Hesseling A, Churchyard G, Kim S, Lando R, Dawson R, Mave V, Mendoza A, Gonzales P, Kumarasamy N, von Groote-Bidlingmaier F, Conradie F, Shenje J, Fontain SN, Garcia-Prats A, Asmelash A, Nedsuwan S, Mohapi L, Mngqibisa R, Garcia Ferreira AC, Okeyo E, Naini L, Jones L, Smith B, Shah NS
published in: The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease
information resource reference: HIV testing uptake among the household contacts of multidrug-resistant tuberculosis index cases in eight countries. Int J Tuberc Lung Dis. 2018 12 01; 22(12):1443-1449.
journal title abbreviation: Int J Tuberc Lung Dis
publication date: 2018-12-01T00:00:00
year: 2018
type: Academic Article
type: Article
type: Document
type: Information Resource

Long term tolerability and safety of enfuvirtide for human immunodeficiency virus 1-infected children.
PubMed Identifier: 15295220
author list: Church JA, Hughes M, Chen J, Palumbo P, Mofenson LM, Delora P, Smith E, Wiznia A, Hawkins E, Sista P, Cunningham CK
published in: The Pediatric infectious disease journal
information resource reference: Long term tolerability and safety of enfuvirtide for human immunodeficiency virus 1-infected children. Pediatr Infect Dis J. 2004 Aug; 23(8):713-8.
journal title abbreviation: Pediatr Infect Dis J
publication date: 2004-08-01T00:00:00
year: 2004
type: Academic Article
type: Article
type: Document
type: Information Resource

HIF-2alpha downregulation in the absence of functional VHL is not sufficient for renal cell differentiation.
PubMed Identifier: 17598890
author list: Hughes MD, Kapllani E, Alexander AE, Burk RD, Schoenfeld AR
published in: Cancer cell international
information resource reference: HIF-2alpha downregulation in the absence of functional VHL is not sufficient for renal cell differentiation. Cancer Cell Int. 2007 Jun 28; 7:13.
journal title abbreviation: Cancer Cell Int
publication date: 2007-06-28T00:00:00
year: 2007
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1126236
type: Authorship
author rank in publication: 3
linked author: Hughes, Michael
linked information resource: Emergence of Extensively Drug-Resistant Salmonella Typhi Infections Among Travelers to or from Pakistan - United States, 2016-2018.

Emergence of Extensively Drug-Resistant Salmonella Typhi Infections Among Travelers to or from Pakistan - United States, 2016-2018.
PubMed Identifier: 30629573
author list: Chatham-Stephens K, Medalla F, Hughes M, Appiah GD, Aubert RD, Caidi H, Angelo KM, Walker AT, Hatley N, Masani S, Nash J, Belko J, Ryan ET, Mintz E, Friedman CR
published in: MMWR. Morbidity and mortality weekly report
information resource reference: Emergence of Extensively Drug-Resistant Salmonella Typhi Infections Among Travelers to or from Pakistan - United States, 2016-2018. MMWR Morb Mortal Wkly Rep. 2019 Jan 11; 68(1):11-13.
journal title abbreviation: MMWR Morb Mortal Wkly Rep
publication date: 2019-01-11T00:00:00
year: 2019
type: Academic Article
type: Article
type: Document
type: Information Resource

Nevirapine- versus lopinavir/ritonavir-based initial therapy for HIV-1 infection among women in Africa: a randomized trial.
PubMed Identifier: 22719231
author list: Lockman S, Hughes M, Sawe F, Zheng Y, McIntyre J, Chipato T, Asmelash A, Rassool M, Kimaiyo S, Shaffer D, Hosseinipour M, Mohapi L, Ssali F, Chibowa M, Amod F, Halvas E, Hogg E, Alston-Smith B, Smith L, Schooley R, Mellors J, Currier J
published in: PLoS medicine
information resource reference: Nevirapine- versus lopinavir/ritonavir-based initial therapy for HIV-1 infection among women in Africa: a randomized trial. PLoS Med. 2012; 9(6):e1001236.
journal title abbreviation: PLoS Med
publication date: 2012-06-12T00:00:00
year: 2012
type: Academic Article
type: Article
type: Document
type: Information Resource

Use of historical marker data for assessing treatment effects in phase I/II trials when subject selection is determined by baseline marker level.
PubMed Identifier: 7548690
author list: Lin HM, Hughes MD
published in: Biometrics
information resource reference: Use of historical marker data for assessing treatment effects in phase I/II trials when subject selection is determined by baseline marker level. Biometrics. 1995 Sep; 51(3):1053-63.
journal title abbreviation: Biometrics
publication date: 1995-09-01T00:00:00
year: 1995
type: Academic Article
type: Article
type: Document
type: Information Resource

Skin Ulcer
MeSH DescriptorUI: D012883
MeSH semantic group name: Disorders
number of authors: 90
number of publications: 128
uniqueness weight: 0.891
type: Concept

Scleroderma, Systemic
MeSH DescriptorUI: D012595
MeSH semantic group name: Disorders
number of authors: 191
number of publications: 369
uniqueness weight: 0.727234
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Authorship 1144848
type: Authorship
author rank in publication: 4
linked author: Hughes, Michael
linked information resource: Feasibility of Identifying Household Contacts of Rifampin-and Multidrug-resistant Tuberculosis Cases at High Risk of Progression to Tuberculosis Disease.

Authorship 1148040
type: Authorship
author rank in publication: 4
linked author: Hughes, Michael
linked information resource: Willingness to Take Multidrug-resistant Tuberculosis (MDR-TB) Preventive Therapy Among Adult and Adolescent Household Contacts of MDR-TB Index Cases: An International Multisite Cross-sectional Study.

Feasibility of Identifying Household Contacts of Rifampin-and Multidrug-resistant Tuberculosis Cases at High Risk of Progression to Tuberculosis Disease.
PubMed Identifier: 30942853
author list: Gupta A, Swindells S, Kim S, Hughes MD, Naini L, Wu X, Dawson R, Mave V, Sanchez J, Mendoza A, Gonzales P, Kumarasamy N, Comins K, Conradie F, Shenje J, Fontain SN, Garcia-Prats A, Asmelash A, Nedsuwan S, Mohapi L, Lalloo UG, Ferreira ACG, Mugah C, Harrington M, Jones L, Cox SR, Smith B, Shah NS, Hesseling AC, Churchyard G
published in: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
information resource reference: Feasibility of Identifying Household Contacts of Rifampin-and Multidrug-resistant Tuberculosis Cases at High Risk of Progression to Tuberculosis Disease. Clin Infect Dis. 2020 01 16; 70(3):425-435.
journal title abbreviation: Clin Infect Dis
publication date: 2020-01-16T00:00:00
year: 2020
type: Academic Article
type: Article
type: Document
type: Information Resource

Willingness to Take Multidrug-resistant Tuberculosis (MDR-TB) Preventive Therapy Among Adult and Adolescent Household Contacts of MDR-TB Index Cases: An International Multisite Cross-sectional Study.
PubMed Identifier: 30919881
author list: Suryavanshi N, Murrill M, Gupta A, Hughes M, Hesseling A, Kim S, Naini L, Jones L, Smith B, Gupte N, Dawson R, Mave V, Meshram S, Mendoza-Ticona A, Sanchez J, Kumarasamy N, Comins K, Conradie F, Shenje J, Nerette Fontain S, Garcia-Prats A, Asmelash A, Nedsuwan S, Mohapi L, Lalloo U, Cristina Garcia Ferreira A, Okeyo E, Swindells S, Churchyard G, Shah NS
published in: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
information resource reference: Willingness to Take Multidrug-resistant Tuberculosis (MDR-TB) Preventive Therapy Among Adult and Adolescent Household Contacts of MDR-TB Index Cases: An International Multisite Cross-sectional Study. Clin Infect Dis. 2020 01 16; 70(3):436-445.
journal title abbreviation: Clin Infect Dis
publication date: 2020-01-16T00:00:00
year: 2020
type: Academic Article
type: Article
type: Document
type: Information Resource

HIV Infections
MeSH DescriptorUI: D015658
MeSH semantic group name: Disorders
number of authors: 2074
number of publications: 18321
uniqueness weight: 0.15142
type: Concept

Anti-HIV Agents
MeSH DescriptorUI: D019380
MeSH semantic group name: Chemicals & Drugs
number of authors: 684
number of publications: 4736
uniqueness weight: 0.313161
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Raynaud Disease
MeSH DescriptorUI: D011928
MeSH semantic group name: Disorders
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number of publications: 87
uniqueness weight: 0.916908
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Authorship 116083
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author rank in publication: 2
linked author: Hughes, Michael
linked information resource: A statistical framework for quantile equivalence clinical trials with application to pharmacokinetic studies that bridge from HIV-infected adults to children.

Authorship 1149732
type: Authorship
author rank in publication: 7
linked author: Hughes, Michael
linked information resource: Flavanol supplementation protects against obesity-associated increases in systemic interleukin-6 levels without inhibiting body mass gain in mice fed a high-fat diet.

Authorship 1150203
type: Authorship
author rank in publication: 5
linked author: Hughes, Michael
linked information resource: Do Negative Changes in Worldview Mediate Links Between Mass Trauma and Reckless Behavior? A Longitudinal Exploratory Study.

Authorship 1150878
type: Authorship
author rank in publication: 4
linked author: Hughes, Michael
linked information resource: When seeking influences believing and promotes posttraumatic adaptation.

Do Negative Changes in Worldview Mediate Links Between Mass Trauma and Reckless Behavior? A Longitudinal Exploratory Study.
PubMed Identifier: 26148489
author list: Blevins CE, Wusik MF, Sullivan CP, Jones RT, Hughes M
published in: Community mental health journal
information resource reference: Do Negative Changes in Worldview Mediate Links Between Mass Trauma and Reckless Behavior? A Longitudinal Exploratory Study. Community Ment Health J. 2016 Jan; 52(1):10-7.
journal title abbreviation: Community Ment Health J
publication date: 2015-07-07T00:00:00
year: 2015
type: Academic Article
type: Article
type: Document
type: Information Resource

Flavanol supplementation protects against obesity-associated increases in systemic interleukin-6 levels without inhibiting body mass gain in mice fed a high-fat diet.
PubMed Identifier: 31051320
author list: Griffin LE, Fausnacht DW, Tuzo JL, Addington AK, Racine KC, Zhang H, Hughes MD, England KM, Bruno RS, O'Keefe SF, Neilson AP, Stewart AC
published in: Nutrition research (New York, N.Y.)
information resource reference: Flavanol supplementation protects against obesity-associated increases in systemic interleukin-6 levels without inhibiting body mass gain in mice fed a high-fat diet. Nutr Res. 2019 06; 66:32-47.
journal title abbreviation: Nutr Res
publication date: 2019-03-21T00:00:00
year: 2019
type: Academic Article
type: Article
type: Document
type: Information Resource

When seeking influences believing and promotes posttraumatic adaptation.
PubMed Identifier: 25264559
author list: Smith AJ, Donlon K, Anderson SR, Hughes M, Jones RT
published in: Anxiety, stress, and coping
information resource reference: When seeking influences believing and promotes posttraumatic adaptation. Anxiety Stress Coping. 2015; 28(3):340-56.
journal title abbreviation: Anxiety Stress Coping
publication date: 2014-10-27T00:00:00
year: 2014
type: Academic Article
type: Article
type: Document
type: Information Resource

Biostatistics
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Center for Biostatistics in AIDS Research
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type: Organization

Immunology and Infectious Diseases
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Medicine
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Pediatrics
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General Internal Medicine
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type: Organization

Infectious Disease
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Beth Israel Deaconess Medical Center
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Brigham and Women's Hospital
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Harvard T.H. Chan School of Public Health
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Massachusetts General Hospital
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Fawzi, Wafaie
eCommons Login: WWF1
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last name: Fawzi
full name: Wafaie W. Fawzi
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Mayer, Kenneth
eCommons Login: KHM2
first name: Kenneth
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Sax, Paul
eCommons Login: PES2
first name: Paul
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Authorship 1158133
type: Authorship
author rank in publication: 4
linked author: Hughes, Michael
linked information resource: Paradoxical New Diagnosis of Giant Cell Arteritis While Receiving Ustekinumab.

Paradoxical New Diagnosis of Giant Cell Arteritis While Receiving Ustekinumab.
PubMed Identifier: 31145223
author list: Sandler RD, Smith R, Kitsanta P, Hughes M
published in: Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases
information resource reference: Paradoxical New Diagnosis of Giant Cell Arteritis While Receiving Ustekinumab. J Clin Rheumatol. 2020 Oct; 26(7):e215-e216.
journal title abbreviation: J Clin Rheumatol
publication date: 2020-10-01T00:00:00
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type: Academic Article
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Lockman, Shahin
eCommons Login: SL15
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Haberer, Jessica
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Li, Jonathan
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Shapiro, Roger
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Pagano, Marcello
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Laird, Nan
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Huttenhower, Curtis
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first name: Curtis
last name: Huttenhower
full name: Curtis Huttenhower, Ph.D.
has faculty rank: Full Professor
latitude: 42.33546850000000
longitude: -71.10151020000000
photo: https://connects.catalyst.harvard.edu/Profiles/profile/Modules/CustomViewPersonGeneralInfo/PhotoHandler.ashx
Person ID: 16016
person in primary position: Professor of Computational Biology and Bioinformatics
type: Agent
type: Person
preferred title: Professor of Computational Biology and Bioinformatics

Betensky, Rebecca
eCommons Login: RAB15
first name: Rebecca
last name: Betensky
full name: Rebecca Aubrey Betensky, Ph.D.
has faculty rank: Full Professor
latitude: 42.33546850000000
longitude: -71.10151020000000
photo: https://connects.catalyst.harvard.edu/Profiles/profile/Modules/CustomViewPersonGeneralInfo/PhotoHandler.ashx
Person ID: 15536
person in primary position: Adjunct Professor of Biostatistics
type: Agent
type: Person
preferred title: Adjunct Professor of Biostatistics

Authorship 1161376
type: Authorship
author rank in publication: 3
linked author: Hughes, Michael
linked information resource: https://connects.catalyst.harvard.edu/Profiles/profile/125095489

https://connects.catalyst.harvard.edu/Profiles/profile/125095489
PubMed Identifier: 31220220
author list: Naggie S, Fierer DS, Hughes MD, Kim AY, Luetkemeyer A, Vu V, Roa J, Rwema S, Brainard DM, McHutchison JG, Peters MG, Kiser JJ, Marks KM, Chung RT
published in: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
information resource reference: Ledipasvir/Sofosbuvir for 8 Weeks to Treat Acute Hepatitis C Virus Infections in Men With Human Immunodeficiency Virus Infections: Sofosbuvir-Containing Regimens Without Interferon for Treatment of Acute HCV in HIV-1 Infected Individuals. Clin Infect Dis. 2019 07 18; 69(3):514-522.
journal title abbreviation: Clin Infect Dis
publication date: 2019-07-18T00:00:00
year: 2019
type: Academic Article
type: Article
type: Document
type: Information Resource
label: Ledipasvir/Sofosbuvir for 8 Weeks to Treat Acute Hepatitis C Virus Infections in Men With Human Immunodeficiency Virus Infections: Sofosbuvir-Containing Regimens Without Interferon for Treatment of Acute HCV in HIV-1 Infected Individuals.

Powis, Kathleen
eCommons Login: KMP13
first name: Kathleen
last name: Powis
full name: Kathleen Marie Powis, M.D.
has faculty rank: Associate Professor
latitude: 42.36241700000000
longitude: -71.06893700000000
Person ID: 4364
person in primary position: Associate Professor of Pediatrics
type: Agent
type: Person
preferred title: Associate Professor of Pediatrics

Dominici, Francesca
eCommons Login: FD27
first name: Francesca
last name: Dominici
full name: Francesca Dominici, Ph.D.
has faculty rank: Full Professor
latitude: 42.33546850000000
longitude: -71.10151020000000
photo: https://connects.catalyst.harvard.edu/Profiles/profile/Modules/CustomViewPersonGeneralInfo/PhotoHandler.ashx
Person ID: 45147
person in primary position: Clarence James Gamble Professor of Biostatistics, Population, and Data Science
type: Agent
type: Person
preferred title: Clarence James Gamble Professor of Biostatistics, Population, and Data Science

Kuritzkes, Daniel
eCommons Login: DRK3
first name: Daniel
last name: Kuritzkes
full name: Daniel Robert Kuritzkes, M.D.
has faculty rank: Full Professor
latitude: 42.36070000000000
longitude: -71.10090000000000
Person ID: 62664
person in primary position: Harriet Ryan Albee Professor of Medicine
type: Agent
type: Person
preferred title: Harriet Ryan Albee Professor of Medicine

Principal Investigator
type: Researcher Role
researcher role of: Hughes, Michael
contributes to: Biostatistics/Epidemiology Training Grants in AIDS

Authorship 1170502
type: Authorship
author rank in publication: 1
linked author: Hughes, Michael
linked information resource: Effect of Season on Internet Searches for Information on Raynaud Phenomenon.

Effect of Season on Internet Searches for Information on Raynaud Phenomenon.
PubMed Identifier: 31308207
author list: Hughes M
published in: The Journal of rheumatology
information resource reference: Effect of Season on Internet Searches for Information on Raynaud Phenomenon. J Rheumatol. 2019 11; 46(11):1543-1544.
journal title abbreviation: J Rheumatol
publication date: 2019-07-15T00:00:00
year: 2019
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 139044
type: Authorship
author rank in publication: 2
linked author: Hughes, Michael
linked information resource: Assessing the effects of interventions using longitudinal data with samples subject to selection.

Authorship 1176584
type: Authorship
author rank in publication: 2
linked author: Hughes, Michael
linked information resource: Third-line antiretroviral therapy in low-income and middle-income countries (ACTG A5288): a prospective strategy study.

Third-line antiretroviral therapy in low-income and middle-income countries (ACTG A5288): a prospective strategy study.
PubMed Identifier: 31371262
author list: Grinsztejn B, Hughes MD, Ritz J, Salata R, Mugyenyi P, Hogg E, Wieclaw L, Gross R, Godfrey C, Cardoso SW, Bukuru A, Makanga M, Faesen S, Mave V, Wangari Ndege B, Nerette Fontain S, Samaneka W, Secours R, van Schalkwyk M, Mngqibisa R, Mohapi L, Valencia J, Sugandhavesa P, Montalban E, Avihingsanon A, Santos BR, Kumarasamy N, Kanyama C, Schooley RT, Mellors JW, Wallis CL, Collier AC
published in: The lancet. HIV
information resource reference: Third-line antiretroviral therapy in low-income and middle-income countries (ACTG A5288): a prospective strategy study. Lancet HIV. 2019 09; 6(9):e588-e600.
journal title abbreviation: Lancet HIV
publication date: 2019-07-29T00:00:00
year: 2019
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1185288
type: Authorship
author rank in publication: 2
linked author: Hughes, Michael
linked information resource: Inclusion of key populations in clinical trials of new antituberculosis treatments: Current barriers and recommendations for pregnant and lactating women, children, and HIV-infected persons.

Inclusion of key populations in clinical trials of new antituberculosis treatments: Current barriers and recommendations for pregnant and lactating women, children, and HIV-infected persons.
PubMed Identifier: 31415563
author list: Gupta A, Hughes MD, Garcia-Prats AJ, McIntire K, Hesseling AC
published in: PLoS medicine
information resource reference: Inclusion of key populations in clinical trials of new antituberculosis treatments: Current barriers and recommendations for pregnant and lactating women, children, and HIV-infected persons. PLoS Med. 2019 08; 16(8):e1002882.
journal title abbreviation: PLoS Med
publication date: 2019-08-15T00:00:00
year: 2019
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1186926
type: Authorship
author rank in publication: 12
linked author: Hughes, Michael
linked information resource: Linked dual-class HIV resistance mutations are associated with treatment failure.

Linked dual-class HIV resistance mutations are associated with treatment failure.
PubMed Identifier: 31487271
author list: Boltz VF, Shao W, Bale MJ, Halvas EK, Luke B, McIntyre JA, Schooley RT, Lockman S, Currier JS, Sawe F, Hogg E, Hughes MD, Kearney MF, Coffin JM, Mellors JW
published in: JCI insight
information resource reference: Linked dual-class HIV resistance mutations are associated with treatment failure. JCI Insight. 2019 10 03; 4(19).
journal title abbreviation: JCI Insight
publication date: 2019-10-03T00:00:00
year: 2019
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1191374
type: Authorship
author rank in publication: 3
linked author: Hughes, Michael
linked information resource: Two-way mobile phone intervention compared with standard-of-care adherence support after second-line antiretroviral therapy failure: a multinational, randomised controlled trial.

Authorship 1190999
type: Authorship
author rank in publication: 16
linked author: Hughes, Michael
linked information resource: Effect of Oral Oseltamivir on Virological Outcomes in Low-risk Adults With Influenza: A Randomized Clinical Trial.

Two-way mobile phone intervention compared with standard-of-care adherence support after second-line antiretroviral therapy failure: a multinational, randomised controlled trial.
PubMed Identifier: 31528850
author list: Gross R, Ritz J, Hughes MD, Salata R, Mugyenyi P, Hogg E, Wieclaw L, Godfrey C, Wallis CL, Mellors JW, Mudhune VO, Badal-Faesen S, Grinsztejn B, Collier AC
published in: The Lancet. Digital health
information resource reference: Two-way mobile phone intervention compared with standard-of-care adherence support after second-line antiretroviral therapy failure: a multinational, randomised controlled trial. Lancet Digit Health. 2019 05; 1(1):e26-e34.
journal title abbreviation: Lancet Digit Health
publication date: 2019-05-06T00:00:00
year: 2019
type: Academic Article
type: Article
type: Document
type: Information Resource

Effect of Oral Oseltamivir on Virological Outcomes in Low-risk Adults With Influenza: A Randomized Clinical Trial.
PubMed Identifier: 31541242
author list: Beigel JH, Manosuthi W, Beeler J, Bao Y, Hoppers M, Ruxrungtham K, Beasley RL, Ison M, Avihingsanon A, Losso MH, Langlois N, Hoopes J, Lane HC, Holley HP, Myers CA, Hughes MD, Davey RT
published in: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
information resource reference: Effect of Oral Oseltamivir on Virological Outcomes in Low-risk Adults With Influenza: A Randomized Clinical Trial. Clin Infect Dis. 2020 05 23; 70(11):2317-2324.
journal title abbreviation: Clin Infect Dis
publication date: 2020-05-23T00:00:00
year: 2020
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 151254
type: Authorship
author rank in publication: 3
linked author: Hughes, Michael
linked information resource: Safety and antiretroviral activity of chronic subcutaneous administration of T-20 in human immunodeficiency virus 1-infected children.

Authorship 1195004
type: Authorship
author rank in publication: 15
linked author: Hughes, Michael
linked information resource: Anti-influenza immune plasma for the treatment of patients with severe influenza A: a randomised, double-blind, phase 3 trial.

Anti-influenza immune plasma for the treatment of patients with severe influenza A: a randomised, double-blind, phase 3 trial.
PubMed Identifier: 31582360
author list: Beigel JH, Aga E, Elie-Turenne MC, Cho J, Tebas P, Clark CL, Metcalf JP, Ozment C, Raviprakash K, Beeler J, Holley HP, Warner S, Chorley C, Lane HC, Hughes MD, Davey RT
published in: The Lancet. Respiratory medicine
information resource reference: Anti-influenza immune plasma for the treatment of patients with severe influenza A: a randomised, double-blind, phase 3 trial. Lancet Respir Med. 2019 11; 7(11):941-950.
journal title abbreviation: Lancet Respir Med
publication date: 2019-09-30T00:00:00
year: 2019
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1205204
type: Authorship
author rank in publication: 2
linked author: Hughes, Michael
linked information resource: https://connects.catalyst.harvard.edu/Profiles/profile/136113982

https://connects.catalyst.harvard.edu/Profiles/profile/136113982
PubMed Identifier: 31724034
author list: Wallis CL, Hughes MD, Ritz J, Viana R, de Jesus CS, Saravanan S, van Schalkwyk M, Mngqibisa R, Salata R, Mugyenyi P, Hogg E, Hovind L, Wieclaw L, Gross R, Godfrey C, Collier AC, Grinsztejn B, Mellors JW
published in: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
information resource reference: Diverse Human Immunodeficiency Virus-1 Drug Resistance Profiles at Screening for ACTG A5288: A Study of People Experiencing Virologic Failure on Second-line Antiretroviral Therapy in Resource-limited Settings. Clin Infect Dis. 2020 10 23; 71(7):e170-e177.
journal title abbreviation: Clin Infect Dis
publication date: 2020-10-23T00:00:00
year: 2020
type: Academic Article
type: Article
type: Document
type: Information Resource
label: Diverse Human Immunodeficiency Virus-1 Drug Resistance Profiles at Screening for ACTG A5288: A Study of People Experiencing Virologic Failure on Second-line Antiretroviral Therapy in Resource-limited Settings.

Harriet Ryan Albee Professor of Medicine
is primary position: true
position in department: Medicine
position in division: Infectious Disease
sort order: 1
type: Position
HR job title: Harriet Ryan Albee Professor of Medicine
position in organization: Brigham and Women's Hospital

Authorship 1210557
type: Authorship
author rank in publication: 1
linked author: Hughes, Michael
linked information resource: Multicenter Qualitative Study Exploring the Patient Experience of Digital Ulcers in Systemic Sclerosis.

Multicenter Qualitative Study Exploring the Patient Experience of Digital Ulcers in Systemic Sclerosis.
PubMed Identifier: 31841265
author list: Hughes M, Pauling JD, Jones J, Denton CP, Domsic RT, Frech TM, Herrick AL, Khanna D, Matucci-Cerinic M, McKenzie L, Saketkoo LA, Gooberman-Hill R, Moore A
published in: Arthritis care & research
information resource reference: Multicenter Qualitative Study Exploring the Patient Experience of Digital Ulcers in Systemic Sclerosis. Arthritis Care Res (Hoboken). 2020 05; 72(5):723-733.
journal title abbreviation: Arthritis Care Res (Hoboken)
publication date: 2020-05-01T00:00:00
year: 2020
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1217690
type: Authorship
author rank in publication: 14
linked author: Hughes, Michael
linked information resource: Safety and Efficacy of Starting Antiretroviral Therapy in the First Week of Life.

Safety and Efficacy of Starting Antiretroviral Therapy in the First Week of Life.
PubMed Identifier: 31927562
author list: Maswabi K, Ajibola G, Bennett K, Capparelli EV, Jean-Philippe P, Moyo S, Mohammed T, Batlang O, Sakoi M, Lockman S, Makhema J, Lichterfeld M, Kuritzkes DR, Hughes MD, Shapiro RL
published in: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
information resource reference: Safety and Efficacy of Starting Antiretroviral Therapy in the First Week of Life. Clin Infect Dis. 2021 02 01; 72(3):388-393.
journal title abbreviation: Clin Infect Dis
publication date: 2021-02-01T00:00:00
year: 2021
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1219691
type: Authorship
author rank in publication: 2
linked author: Hughes, Michael
linked information resource: Osteomyelitis Complicating Digital Ulcer Disease.

Osteomyelitis Complicating Digital Ulcer Disease.
PubMed Identifier: 31977650
author list: Cox M, Hughes M
published in: Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases
information resource reference: Osteomyelitis Complicating Digital Ulcer Disease. J Clin Rheumatol. 2021 Sep 01; 27(6):e230-e231.
journal title abbreviation: J Clin Rheumatol
publication date: 2021-09-01T00:00:00
year: 2021
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1222416
type: Authorship
author rank in publication: 2
linked author: Hughes, Michael
linked information resource: Sample size estimation for stratified individual and cluster randomized trials with binary outcomes.

Sample size estimation for stratified individual and cluster randomized trials with binary outcomes.
PubMed Identifier: 32003492
author list: Kennedy-Shaffer L, Hughes MD
published in: Statistics in medicine
information resource reference: Sample size estimation for stratified individual and cluster randomized trials with binary outcomes. Stat Med. 2020 05 15; 39(10):1489-1513.
journal title abbreviation: Stat Med
publication date: 2020-01-31T00:00:00
year: 2020
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1223465
type: Authorship
author rank in publication: 11
linked author: Hughes, Michael
linked information resource: Generation of light-producing somatic-transgenic mice using adeno-associated virus vectors.

Authorship 1222902
type: Authorship
author rank in publication: 1
linked author: Hughes, Michael
linked information resource: Patient experiences of digital ulcer development and evolution in systemic sclerosis.

Patient experiences of digital ulcer development and evolution in systemic sclerosis.
PubMed Identifier: 32031630
author list: Hughes M, Pauling JD, Jones J, Denton CP, Domsic RT, Frech TM, Herrick AL, Khanna D, Matucci-Cerinic M, McKenzie L, Saketkoo LA, Gooberman-Hill R, Moore A
published in: Rheumatology (Oxford, England)
information resource reference: Patient experiences of digital ulcer development and evolution in systemic sclerosis. Rheumatology (Oxford). 2020 08 01; 59(8):2156-2158.
journal title abbreviation: Rheumatology (Oxford)
publication date: 2020-08-01T00:00:00
year: 2020
type: Academic Article
type: Article
type: Document
type: Information Resource

Generation of light-producing somatic-transgenic mice using adeno-associated virus vectors.
PubMed Identifier: 32034258
author list: Karda R, Rahim AA, Wong AMS, Suff N, Diaz JA, Perocheau DP, Tijani M, Ng J, Baruteau J, Martin NP, Hughes M, Delhove JMKM, Counsell JR, Cooper JD, Henckaerts E, Mckay TR, Buckley SMK, Waddington SN
published in: Scientific reports
information resource reference: Generation of light-producing somatic-transgenic mice using adeno-associated virus vectors. Sci Rep. 2020 02 07; 10(1):2121.
journal title abbreviation: Sci Rep
publication date: 2020-02-07T00:00:00
year: 2020
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 120918
type: Authorship
author rank in publication: 1
linked author: Hughes, Michael
linked information resource: The search for data on when to start treatment for HIV infection.

Authorship 1225918
type: Authorship
author rank in publication: 1
linked author: Hughes, Michael
linked information resource: Gender-related differences in systemic sclerosis.

Authorship 1225472
type: Authorship
author rank in publication: 2
linked author: Hughes, Michael
linked information resource: Brief Report: Sex Differences in Outcomes for Individuals Presenting for Third-Line Antiretroviral Therapy.

Gender-related differences in systemic sclerosis.
PubMed Identifier: 32062031
author list: Hughes M, Pauling JD, Armstrong-James L, Denton CP, Galdas P, Flurey C
published in: Autoimmunity reviews
information resource reference: Gender-related differences in systemic sclerosis. Autoimmun Rev. 2020 Apr; 19(4):102494.
journal title abbreviation: Autoimmun Rev
publication date: 2020-02-13T00:00:00
year: 2020
type: Academic Article
type: Article
type: Document
type: Information Resource

Brief Report: Sex Differences in Outcomes for Individuals Presenting for Third-Line Antiretroviral Therapy.
PubMed Identifier: 32049773
author list: Godfrey C, Hughes MD, Ritz J, Coelho L, Gross R, Salata R, Mngqibisa R, Wallis CL, Mumbi ME, Matoga M, Poongulali S, Van Schalkwyk M, Hogg E, Fletcher CV, Grinsztejn B, Collier AC
published in: Journal of acquired immune deficiency syndromes (1999)
information resource reference: Brief Report: Sex Differences in Outcomes for Individuals Presenting for Third-Line Antiretroviral Therapy. J Acquir Immune Defic Syndr. 2020 06 01; 84(2):203-207.
journal title abbreviation: J Acquir Immune Defic Syndr
publication date: 2020-06-01T00:00:00
year: 2020
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 121669
type: Authorship
author rank in publication: 5
linked author: Hughes, Michael
linked information resource: A case-crossover analysis of predictors of condom use by female bar and hotel workers in Moshi, Tanzania.

Authorship 1231616
type: Authorship
author rank in publication: 6
linked author: Hughes, Michael
linked information resource: Mother-to-Child HIV Transmission With In Utero Dolutegravir vs. Efavirenz in Botswana.

Mother-to-Child HIV Transmission With In Utero Dolutegravir vs. Efavirenz in Botswana.
PubMed Identifier: 32195745
author list: Davey S, Ajibola G, Maswabi K, Sakoi M, Bennett K, Hughes MD, Isaacson A, Diseko M, Zash R, Batlang O, Moyo S, Lockman S, Lichterfeld M, Kuritzkes DR, Makhema J, Shapiro R
published in: Journal of acquired immune deficiency syndromes (1999)
information resource reference: Mother-to-Child HIV Transmission With In Utero Dolutegravir vs. Efavirenz in Botswana. J Acquir Immune Defic Syndr. 2020 07 01; 84(3):235-241.
journal title abbreviation: J Acquir Immune Defic Syndr
publication date: 2020-07-01T00:00:00
year: 2020
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 178866
type: Authorship
author rank in publication: 1
linked author: Hughes, Michael
linked information resource: Analysis and design issues for studies using censored biomarker measurements with an example of viral load measurements in HIV clinical trials.

HIV diagnostic algorithm requires confirmatory testing for initial indeterminate or positive screens in the first week of life.
PubMed Identifier: 32287064
author list: Ajibola G, Moyo S, Mohammed T, Moseki S, Jack D, Sakoi M, Batlang O, Maswabi K, Bennett K, Hughes MD, Lockman S, Makhema JM, Lichterfeld M, Kuritzkes DR, Shapiro RL
published in: AIDS (London, England)
information resource reference: HIV diagnostic algorithm requires confirmatory testing for initial indeterminate or positive screens in the first week of life. AIDS. 2020 06 01; 34(7):1029-1035.
journal title abbreviation: AIDS
publication date: 2020-06-01T00:00:00
year: 2020
type: Academic Article
type: Article
type: Document
type: Information Resource

Trials of Tuberculosis-Preventive Therapy in People with HIV Infection.
PubMed Identifier: 32282226
author list: Swindells S, Hughes M, Chaisson RE
published in: American journal of respiratory and critical care medicine
information resource reference: Trials of Tuberculosis-Preventive Therapy in People with HIV Infection. Am J Respir Crit Care Med. 2020 07 15; 202(2):304-305.
journal title abbreviation: Am J Respir Crit Care Med
publication date: 2020-07-15T00:00:00
year: 2020
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1241502
type: Authorship
author rank in publication: 10
linked author: Hughes, Michael
linked information resource: HIV diagnostic algorithm requires confirmatory testing for initial indeterminate or positive screens in the first week of life.

Authorship 1242107
type: Authorship
author rank in publication: 2
linked author: Hughes, Michael
linked information resource: Trials of Tuberculosis-Preventive Therapy in People with HIV Infection.

Authorship 1244980
type: Authorship
author rank in publication: 2
linked author: Hughes, Michael
linked information resource: Forgetting "routine" deep venous thrombosis and stroke during COVID-19 is a parallel pandemic that will be costly if ignored.

Forgetting "routine" deep venous thrombosis and stroke during COVID-19 is a parallel pandemic that will be costly if ignored.
PubMed Identifier: 32360375
author list: Rogers SK, Hughes M
published in: Journal of vascular surgery
information resource reference: Forgetting "routine" deep venous thrombosis and stroke during COVID-19 is a parallel pandemic that will be costly if ignored. J Vasc Surg. 2020 Aug; 72(2):761-763.
journal title abbreviation: J Vasc Surg
publication date: 2020-04-30T00:00:00
year: 2020
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1248935
type: Authorship
author rank in publication: 5
linked author: Hughes, Michael
linked information resource: Gastric Electrical Stimulators Causing Erosion Through the Colonic Wall.

Gastric Electrical Stimulators Causing Erosion Through the Colonic Wall.
PubMed Identifier: 32440521
author list: Condon S, Patel A, Shah N, Stocker A, Hughes M, Farmer R, Abell T
published in: ACG case reports journal
information resource reference: Gastric Electrical Stimulators Causing Erosion Through the Colonic Wall. ACG Case Rep J. 2020 Feb; 7(2):e00313.
journal title abbreviation: ACG Case Rep J
publication date: 2020-03-02T00:00:00
year: 2020
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1256091
type: Authorship
author rank in publication: 2
linked author: Hughes, Michael
linked information resource: Digital artery vasospasm in primary Raynaud's phenomenon.

Digital artery vasospasm in primary Raynaud's phenomenon.
PubMed Identifier: 32525479
author list: Rogers S, Hughes M
published in: European journal of rheumatology
information resource reference: Digital artery vasospasm in primary Raynaud's phenomenon. Eur J Rheumatol. 2020 Jun 08.
journal title abbreviation: Eur J Rheumatol
publication date: 2020-06-08T00:00:00
year: 2020
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1265906
type: Authorship
author rank in publication: 6
linked author: Hughes, Michael
linked information resource: Immune donors can protect marrow-transplant recipients from severe cytomegalovirus infections.

Immune donors can protect marrow-transplant recipients from severe cytomegalovirus infections.
PubMed Identifier: 2882184
author list: Grob JP, Grundy JE, Prentice HG, Griffiths PD, Hoffbrand AV, Hughes MD, Tate T, Wimperis JZ, Brenner MK
published in: Lancet (London, England)
information resource reference: Immune donors can protect marrow-transplant recipients from severe cytomegalovirus infections. Lancet. 1987 Apr 04; 1(8536):774-6.
journal title abbreviation: Lancet
publication date: 1987-04-04T00:00:00
year: 1987
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 143953
type: Authorship
author rank in publication: 4
linked author: Hughes, Michael
linked information resource: The values of quantitative serum HIV-1 RNA levels and CD4 cell counts for predicting survival time among HIV-positive individuals with CD4 counts of < or = 50 x 10(6) cells/l.

Authorship 202321
type: Authorship
author rank in publication: 1
linked author: Hughes, Michael
linked information resource: Reporting Bayesian analyses of clinical trials.

Global Health and Population
type: Department
type: Organization

Authorship 1307394
type: Authorship
author rank in publication: 3
linked author: Hughes, Michael
linked information resource: Typhoid Fever in the US Pediatric Population, 1999-2015: Opportunities for Improvement.

Typhoid Fever in the US Pediatric Population, 1999-2015: Opportunities for Improvement.
PubMed Identifier: 33247585
author list: McAteer J, Derado G, Hughes M, Bhatnagar A, Medalla F, Chatham-Stevens K, Appiah GD, Mintz E
published in: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
information resource reference: Typhoid Fever in the US Pediatric Population, 1999-2015: Opportunities for Improvement. Clin Infect Dis. 2021 12 06; 73(11):e4581-e4589.
journal title abbreviation: Clin Infect Dis
publication date: 2021-12-06T00:00:00
year: 2021
type: Academic Article
type: Article
type: Document
type: Information Resource

Decreased diarrheal and respiratory disease in HIV exposed uninfected children following vaccination with rotavirus and pneumococcal conjugate vaccines.
PubMed Identifier: 33347474
author list: Ajibola G, Bennett K, Powis KM, Hughes MD, Leidner J, Kgole S, Batlang O, Mmalane M, Makhema J, Lockman S, Shapiro R
published in: PloS one
information resource reference: Decreased diarrheal and respiratory disease in HIV exposed uninfected children following vaccination with rotavirus and pneumococcal conjugate vaccines. PLoS One. 2020; 15(12):e0244100.
journal title abbreviation: PLoS One
publication date: 2020-12-21T00:00:00
year: 2020
type: Academic Article
type: Article
type: Document
type: Information Resource

Hand Osteomyelitis in Patients With Secondary Raynaud Phenomenon.
PubMed Identifier: 33337814
author list: Haque A, Wyman M, Dargan D, Hughes M, Musson R, Caddick J, Giblin V
published in: Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases
information resource reference: Hand Osteomyelitis in Patients With Secondary Raynaud Phenomenon. J Clin Rheumatol. 2021 Dec 01; 27(8S):S342-S345.
journal title abbreviation: J Clin Rheumatol
publication date: 2021-12-01T00:00:00
year: 2021
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1312030
type: Authorship
author rank in publication: 4
linked author: Hughes, Michael
linked information resource: Decreased diarrheal and respiratory disease in HIV exposed uninfected children following vaccination with rotavirus and pneumococcal conjugate vaccines.

Authorship 1313571
type: Authorship
author rank in publication: 4
linked author: Hughes, Michael
linked information resource: Hand Osteomyelitis in Patients With Secondary Raynaud Phenomenon.

Authorship 1323749
type: Authorship
author rank in publication: 10
linked author: Hughes, Michael
linked information resource: Poor quality of life and incomplete self-reported adherence predict second-line ART virological failure in resource-limited settings.

Authorship 1323747
type: Authorship
author rank in publication: 4
linked author: Hughes, Michael
linked information resource: How do patients define Raynaud's phenomenon? Differences between primary and secondary disease.

How do patients define Raynaud's phenomenon? Differences between primary and secondary disease.
PubMed Identifier: 33486597
author list: Murphy SL, Lescoat A, Alore M, Hughes M, Pauling JD, Sabbagh M, Khanna D
published in: Clinical rheumatology
information resource reference: How do patients define Raynaud's phenomenon? Differences between primary and secondary disease. Clin Rheumatol. 2021 Apr; 40(4):1611-1616.
journal title abbreviation: Clin Rheumatol
publication date: 2021-01-24T00:00:00
year: 2021
type: Academic Article
type: Article
type: Document
type: Information Resource

Poor quality of life and incomplete self-reported adherence predict second-line ART virological failure in resource-limited settings.
PubMed Identifier: 33487029
author list: Torres TS, Harrison LJ, La Rosa AM, Zheng L, Cardoso SW, Ulaya G, Akoojee N, Kadam D, Collier AC, Hughes MD
published in: AIDS care
information resource reference: Poor quality of life and incomplete self-reported adherence predict second-line ART virological failure in resource-limited settings. AIDS Care. 2021 10; 33(10):1340-1349.
journal title abbreviation: AIDS Care
publication date: 2021-01-23T00:00:00
year: 2021
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1326082
type: Authorship
author rank in publication: 4
linked author: Hughes, Michael
linked information resource: Correction to: How do patients define Raynaud's phenomenon? Differences between primary and secondary disease.

Correction to: How do patients define Raynaud's phenomenon? Differences between primary and secondary disease.
PubMed Identifier: 33547561
author list: Murphy SL, Lescoat A, Alore M, Hughes M, Pauling JD, Sabbagh M, Khanna D
published in: Clinical rheumatology
information resource reference: Correction to: How do patients define Raynaud's phenomenon? Differences between primary and secondary disease. Clin Rheumatol. 2021 Apr; 40(4):1617-1620.
journal title abbreviation: Clin Rheumatol
publication date: 2021-04-01T00:00:00
year: 2021
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1328999
type: Authorship
author rank in publication: 2
linked author: Hughes, Michael
linked information resource: Use of dietary phytochemicals for inhibition of trimethylamine N-oxide formation.

Use of dietary phytochemicals for inhibition of trimethylamine N-oxide formation.
PubMed Identifier: 33577949
author list: Iglesias-Carres L, Hughes MD, Steele CN, Ponder MA, Davy KP, Neilson AP
published in: The Journal of nutritional biochemistry
information resource reference: Use of dietary phytochemicals for inhibition of trimethylamine N-oxide formation. J Nutr Biochem. 2021 05; 91:108600.
journal title abbreviation: J Nutr Biochem
publication date: 2021-02-09T00:00:00
year: 2021
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1331391
type: Authorship
author rank in publication: 5
linked author: Hughes, Michael
linked information resource: Viral Reservoir in Early-Treated Human Immunodeficiency Virus-Infected Children and Markers for Sustained Viral Suppression.

Viral Reservoir in Early-Treated Human Immunodeficiency Virus-Infected Children and Markers for Sustained Viral Suppression.
PubMed Identifier: 33605999
author list: Ajibola G, Garcia-Broncano P, Maswabi K, Bennett K, Hughes MD, Moyo S, Mohammed T, Jean-Philippe P, Sakoi M, Batlang O, Lockman S, Makhema J, Kuritzkes DR, Lichterfeld M, Shapiro RL
published in: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
information resource reference: Viral Reservoir in Early-Treated Human Immunodeficiency Virus-Infected Children and Markers for Sustained Viral Suppression. Clin Infect Dis. 2021 08 16; 73(4):e997-e1003.
journal title abbreviation: Clin Infect Dis
publication date: 2021-08-16T00:00:00
year: 2021
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1333361
type: Authorship
author rank in publication: 5
linked author: Hughes, Michael
linked information resource: Drug susceptibility patterns of Mycobacterium tuberculosis from adults with multidrug-resistant tuberculosis and implications for a household contact preventive therapy trial.

Drug susceptibility patterns of Mycobacterium tuberculosis from adults with multidrug-resistant tuberculosis and implications for a household contact preventive therapy trial.
PubMed Identifier: 33627075
author list: Demers AM, Kim S, McCallum S, Eisenach K, Hughes M, Naini L, Mendoza-Ticona A, Pradhan N, Narunsky K, Poongulali S, Badal-Faesen S, Upton C, Smith E, Shah NS, Churchyard G, Gupta A, Hesseling A, Swindells S
published in: BMC infectious diseases
information resource reference: Drug susceptibility patterns of Mycobacterium tuberculosis from adults with multidrug-resistant tuberculosis and implications for a household contact preventive therapy trial. BMC Infect Dis. 2021 Feb 24; 21(1):205.
journal title abbreviation: BMC Infect Dis
publication date: 2021-02-24T00:00:00
year: 2021
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 247823
type: Authorship
author rank in publication: 4
linked author: Hughes, Michael
linked information resource: Treatment responses in antiretroviral treatment-naive premenopausal and postmenopausal HIV-1-infected women: an analysis from AIDS Clinical Trials Group Studies.

Authorship 1337003
type: Authorship
author rank in publication: 3
linked author: Hughes, Michael
linked information resource: Ultrasonographic imaging of systemic sclerosis digital ulcers: A systematic literature review and validation steps.

Ultrasonographic imaging of systemic sclerosis digital ulcers: A systematic literature review and validation steps.
PubMed Identifier: 33677309
author list: Suliman YA, Bruni C, Hughes M, Matucci-Cerinic M, Furst DE
published in: Seminars in arthritis and rheumatism
information resource reference: Ultrasonographic imaging of systemic sclerosis digital ulcers: A systematic literature review and validation steps. Semin Arthritis Rheum. 2021 04; 51(2):425-429.
journal title abbreviation: Semin Arthritis Rheum
publication date: 2021-02-19T00:00:00
year: 2021
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1342147
type: Authorship
author rank in publication: 4
linked author: Hughes, Michael
linked information resource: Resistance to Mycobacterium tuberculosis Infection Among Household Contacts: A Multinational Study.

Resistance to Mycobacterium tuberculosis Infection Among Household Contacts: A Multinational Study.
PubMed Identifier: 33772550
author list: Baliashvili D, Gandhi NR, Kim S, Hughes M, Mave V, Mendoza-Ticona A, Gonzales P, Narunsky K, Selvamuthu P, Badal-Faesen S, Upton C, Naini L, Smith E, Gupta A, Churchyard G, Swindells S, Hesseling A, Shah NS
published in: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
information resource reference: Resistance to Mycobacterium tuberculosis Infection Among Household Contacts: A Multinational Study. Clin Infect Dis. 2021 09 15; 73(6):1037-1045.
journal title abbreviation: Clin Infect Dis
publication date: 2021-09-15T00:00:00
year: 2021
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1343084
type: Authorship
author rank in publication: 3
linked author: Hughes, Michael
linked information resource: Antiretroviral hair levels, self-reported adherence, and virologic failure in second-line regimen patients in resource-limited settings.

Antiretroviral hair levels, self-reported adherence, and virologic failure in second-line regimen patients in resource-limited settings.
PubMed Identifier: 33831905
author list: Apornpong T, Grinsztejn B, Hughes M, Ritz J, Kerr SJ, Fletcher CV, Ruxrungtham K, Godfrey C, Gross R, Hogg E, Wallis CL, Badal-Faesen S, Hosseinipour MC, Mngqbisa R, Santos BR, Shah S, Hovind LJ, Mawlana S, Van Schalkwyk M, Chotirosniramit N, Kanyama C, Kumarasamy N, Salata R, Collier AC, Gandhi M
published in: AIDS (London, England)
information resource reference: Antiretroviral hair levels, self-reported adherence, and virologic failure in second-line regimen patients in resource-limited settings. AIDS. 2021 07 15; 35(9):1439-1449.
journal title abbreviation: AIDS
publication date: 2021-07-15T00:00:00
year: 2021
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1355063
type: Authorship
author rank in publication: 10
linked author: Hughes, Michael
linked information resource: Symmetry breaking of tissue mechanics in wound induced hair follicle regeneration of laboratory and spiny mice.

Symmetry breaking of tissue mechanics in wound induced hair follicle regeneration of laboratory and spiny mice.
PubMed Identifier: 33972536
author list: Harn HI, Wang SP, Lai YC, Van Handel B, Liang YC, Tsai S, Schiessl IM, Sarkar A, Xi H, Hughes M, Kaemmer S, Tang MJ, Peti-Peterdi J, Pyle AD, Woolley TE, Evseenko D, Jiang TX, Chuong CM
published in: Nature communications
information resource reference: Symmetry breaking of tissue mechanics in wound induced hair follicle regeneration of laboratory and spiny mice. Nat Commun. 2021 05 10; 12(1):2595.
journal title abbreviation: Nat Commun
publication date: 2021-05-10T00:00:00
year: 2021
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 256361
type: Authorship
author rank in publication: 2
linked author: Hughes, Michael
linked information resource: Effect of lamivudine in HIV-infected persons with prior exposure to zidovudine/didanosine or zidovudine/zalcitabine.

Authorship 1379217
type: Authorship
author rank in publication: 5
linked author: Hughes, Michael
linked information resource: Considerations for a combined index for limited cutaneous systemic sclerosis to support drug development and improve outcomes.

Considerations for a combined index for limited cutaneous systemic sclerosis to support drug development and improve outcomes.
PubMed Identifier: 34316516
author list: Lescoat A, Murphy SL, Roofeh D, Pauling JD, Hughes M, Sandler R, Zimmermann F, Wessel R, Townsend W, Chung L, Denton CP, Merkel PA, Steen V, Allanore Y, Del Galdo F, Godard D, Cella D, Farrington S, Buch MH, Khanna D
published in: Journal of scleroderma and related disorders
information resource reference: Considerations for a combined index for limited cutaneous systemic sclerosis to support drug development and improve outcomes. J Scleroderma Relat Disord. 2021 Feb 01; 6(1):66-76.
journal title abbreviation: J Scleroderma Relat Disord
publication date: 2020-10-05T00:00:00
year: 2020
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 160739
type: Authorship
author rank in publication: 6
linked author: Hughes, Michael
linked information resource: Clinical response and tolerability to and safety of saquinavir with low-dose ritonavir in human immunodeficiency virus type 1-infected mothers and their infants.

Authorship 1395817
type: Authorship
author rank in publication: 8
linked author: Hughes, Michael
linked information resource: Emergence of SARS-CoV-2 Resistance with Monoclonal Antibody Therapy.

Emergence of SARS-CoV-2 Resistance with Monoclonal Antibody Therapy.
PubMed Identifier: 34545376
author list: Choudhary MC, Chew KW, Deo R, Flynn JP, Regan J, Crain CR, Moser C, Hughes M, Ritz J, Ribeiro RM, Ke R, Dragavon JA, Javan AC, Nirula A, Klekotka P, Greninger AL, Fletcher CV, Daar ES, Wohl DA, Eron JJ, Currier JS, Parikh UM, Sieg SF, Perelson AS, Coombs RW, Smith DM, Li JZ
published in: medRxiv : the preprint server for health sciences
information resource reference: Emergence of SARS-CoV-2 Resistance with Monoclonal Antibody Therapy. medRxiv. 2021 Sep 15.
journal title abbreviation: medRxiv
publication date: 2021-09-15T00:00:00
year: 2021
type: Academic Article
type: Article
type: Document
type: Information Resource

Professor of Medicine
is primary position: true
position in department: Medicine
position in division: General Internal Medicine
sort order: 1
type: Position
HR job title: Professor of Medicine
position in organization: Massachusetts General Hospital

Authorship 1400634
type: Authorship
author rank in publication: 5
linked author: Hughes, Michael
linked information resource: Prebiotic Inulin Supplementation and Peripheral Insulin Sensitivity in adults at Elevated Risk for Type 2 Diabetes: A Pilot Randomized Controlled Trial.

Authorship 1401142
type: Authorship
author rank in publication: 2
linked author: Hughes, Michael
linked information resource: Racial identity and the quality of life among blacks and whites in the U.S.

Prebiotic Inulin Supplementation and Peripheral Insulin Sensitivity in adults at Elevated Risk for Type 2 Diabetes: A Pilot Randomized Controlled Trial.
PubMed Identifier: 34579112
author list: Mitchell CM, Davy BM, Ponder MA, McMillan RP, Hughes MD, Hulver MW, Neilson AP, Davy KP
published in: Nutrients
information resource reference: Prebiotic Inulin Supplementation and Peripheral Insulin Sensitivity in adults at Elevated Risk for Type 2 Diabetes: A Pilot Randomized Controlled Trial. Nutrients. 2021 Sep 17; 13(9).
journal title abbreviation: Nutrients
publication date: 2021-09-17T00:00:00
year: 2021
type: Academic Article
type: Article
type: Document
type: Information Resource

Racial identity and the quality of life among blacks and whites in the U.S.
PubMed Identifier: 28888292
author list: Jill Kiecolt K, Hughes M
published in: Social science research
information resource reference: Racial identity and the quality of life among blacks and whites in the U.S. Soc Sci Res. 2017 Sep; 67:59-71.
journal title abbreviation: Soc Sci Res
publication date: 2017-08-09T00:00:00
year: 2017
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1418169
type: Authorship
author rank in publication: 2
linked author: Hughes, Michael
linked information resource: Power and sample size calculations for cluster randomized trials with binary outcomes when intracluster correlation coefficients vary by treatment arm.

Power and sample size calculations for cluster randomized trials with binary outcomes when intracluster correlation coefficients vary by treatment arm.
PubMed Identifier: 34879711
author list: Kennedy-Shaffer L, Hughes MD
published in: Clinical trials (London, England)
information resource reference: Power and sample size calculations for cluster randomized trials with binary outcomes when intracluster correlation coefficients vary by treatment arm. Clin Trials. 2022 02; 19(1):42-51.
journal title abbreviation: Clin Trials
publication date: 2021-12-08T00:00:00
year: 2021
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1421721
type: Authorship
author rank in publication: 22
linked author: Hughes, Michael
linked information resource: Bamlanivimab reduces nasopharyngeal SARS-CoV-2 RNA levels but not symptom duration in non-hospitalized adults with COVID-19: A Phase 2 Randomized Clinical Trial.

Bamlanivimab reduces nasopharyngeal SARS-CoV-2 RNA levels but not symptom duration in non-hospitalized adults with COVID-19: A Phase 2 Randomized Clinical Trial.
PubMed Identifier: 34981077
author list: Chew KW, Moser C, Daar ES, Wohl DA, Li JZ, Coombs R, Ritz J, Giganti M, Javan AC, Li Y, Malvestutto C, Klekotka P, Price K, Nirula A, Fischer W, Bala V, Ribeiro RM, Perelson AS, Fletcher CV, Eron JJ, Currier JS, Hughes MD, Smith DM
published in: medRxiv : the preprint server for health sciences
information resource reference: Bamlanivimab reduces nasopharyngeal SARS-CoV-2 RNA levels but not symptom duration in non-hospitalized adults with COVID-19: A Phase 2 Randomized Clinical Trial. medRxiv. 2021 Dec 21.
journal title abbreviation: medRxiv
publication date: 2021-12-21T00:00:00
year: 2021
type: Academic Article
type: Article
type: Document
type: Information Resource

Monoclonal antibody treatment drives rapid culture conversion in SARS-CoV-2 infection.
PubMed Identifier: 35018382
author list: Boucau J, Chew KW, Choudhary M, Deo R, Regan J, Flynn JP, Crain CR, Hughes MD, Ritz J, Moser C, Dragavon JA, Javan AC, Nirula A, Klekotka P, Greninger AL, Coombs RW, Fischer WA, Daar ES, Wohl DA, Eron JJ, Currier JS, Smith DM, Li JZ, Barczak AK
published in: medRxiv : the preprint server for health sciences
information resource reference: Monoclonal antibody treatment drives rapid culture conversion in SARS-CoV-2 infection. medRxiv. 2021 Dec 30.
journal title abbreviation: medRxiv
publication date: 2021-12-30T00:00:00
year: 2021
type: Academic Article
type: Article
type: Document
type: Information Resource

Perceptual Measures of Boychoir Voices During the Phases of Pubertal Voice Mutation.
PubMed Identifier: 32402661
author list: Weinrich B, Brehm SB, LeBorgne W, Eanes C, Zacharias S, Beckmeyer J, Hughes M, de Alarcon A
published in: Journal of voice : official journal of the Voice Foundation
information resource reference: Perceptual Measures of Boychoir Voices During the Phases of Pubertal Voice Mutation. J Voice. 2022 Jan; 36(1):142.e1-142.e8.
journal title abbreviation: J Voice
publication date: 2020-05-10T00:00:00
year: 2020
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1425149
type: Authorship
author rank in publication: 7
linked author: Hughes, Michael
linked information resource: Perceptual Measures of Boychoir Voices During the Phases of Pubertal Voice Mutation.

Authorship 1425583
type: Authorship
author rank in publication: 8
linked author: Hughes, Michael
linked information resource: Monoclonal antibody treatment drives rapid culture conversion in SARS-CoV-2 infection.

Authorship 229260
type: Authorship
author rank in publication: 2
linked author: Hughes, Michael
linked information resource: Lipid and glucose alterations in HIV-infected children beginning or changing antiretroviral therapy.

Authorship 1431799
type: Authorship
author rank in publication: 5
linked author: Hughes, Michael
linked information resource: Domains and outcome measures for the assessment of limited cutaneous systemic sclerosis: an international collaborative scoping review.

Domains and outcome measures for the assessment of limited cutaneous systemic sclerosis: an international collaborative scoping review.
PubMed Identifier: 35094049
author list: Lescoat A, Sandler RD, Zimmermann F, Roofeh D, Hughes M, Pauling JD, Murphy SL, Chen YT, Townsend W, Buch MH, Khanna D
published in: Rheumatology (Oxford, England)
information resource reference: Domains and outcome measures for the assessment of limited cutaneous systemic sclerosis: an international collaborative scoping review. Rheumatology (Oxford). 2022 08 03; 61(8):3132-3148.
journal title abbreviation: Rheumatology (Oxford)
publication date: 2022-08-03T00:00:00
year: 2022
type: Academic Article
type: Article
type: Document
type: Information Resource

The case for altruism in institutional diagnostic testing.
PubMed Identifier: 35115545
author list: Specht I, Sani K, Botti-Lodovico Y, Hughes M, Heumann K, Bronson A, Marshall J, Baron E, Parrie E, Glennon O, Fry B, Colubri A, Sabeti PC
published in: Scientific reports
information resource reference: The case for altruism in institutional diagnostic testing. Sci Rep. 2022 02 03; 12(1):1857.
journal title abbreviation: Sci Rep
publication date: 2022-02-03T00:00:00
year: 2022
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1441967
type: Authorship
author rank in publication: 1
linked author: Hughes, Michael
linked information resource: A pilot study using high-frequency ultrasound to measure digital ulcers: a possible outcome measure in systemic sclerosis clinical trials?

Authorship 1440835
type: Authorship
author rank in publication: 1
linked author: Hughes, Michael
linked information resource: Should all digital ulcers be included in future clinical trials of systemic sclerosis-related digital vasculopathy?

Authorship 1441476
type: Authorship
author rank in publication: 3
linked author: Hughes, Michael
linked information resource: High Prevalence of Tuberculosis Infection and Disease in Child Household Contacts of Adults With Rifampin-resistant Tuberculosis.

Authorship 1439845
type: Authorship
author rank in publication: 1
linked author: Hughes, Michael
linked information resource: Reliability of digital ulcer definitions as proposed by the UK Scleroderma Study Group: A challenge for clinical trial design.

Authorship 1440096
type: Authorship
author rank in publication: 2
linked author: Hughes, Michael
linked information resource: Similarities between COVID-19 and systemic sclerosis early vasculopathy: A "viral" challenge for future research in scleroderma.

Authorship 1440892
type: Authorship
author rank in publication: 1
linked author: Hughes, Michael
linked information resource: Digital ulcers in systemic sclerosis.

Authorship 1441783
type: Authorship
author rank in publication: 1
linked author: Hughes, Michael
linked information resource: Further evidence that calcinosis is associated with repetitive trauma in systemic sclerosis.

Authorship 1442614
type: Authorship
author rank in publication: 1
linked author: Hughes, Michael
linked information resource: Imaging calcinosis in patients with systemic sclerosis by radiography, computerised tomography and magnetic resonance imaging.

Authorship 1436960
type: Authorship
author rank in publication: 1
linked author: Hughes, Michael
linked information resource: Haemoglobinopathies and the rheumatologist.

Authorship 1439847
type: Authorship
author rank in publication: 1
linked author: Hughes, Michael
linked information resource: https://connects.catalyst.harvard.edu/Profiles/profile/194565592

Authorship 1442430
type: Authorship
author rank in publication: 2
linked author: Hughes, Michael
linked information resource: Force adaptive robotically assisted endomicroscopy for intraoperative tumour identification.

Authorship 1442738
type: Authorship
author rank in publication: 1
linked author: Hughes, Michael
linked information resource: Raynaud's phenomenon.

Similarities between COVID-19 and systemic sclerosis early vasculopathy: A "viral" challenge for future research in scleroderma.
PubMed Identifier: 34274540
author list: Matucci-Cerinic M, Hughes M, Taliani G, Kahaleh B
published in: Autoimmunity reviews
information resource reference: Similarities between COVID-19 and systemic sclerosis early vasculopathy: A "viral" challenge for future research in scleroderma. Autoimmun Rev. 2021 Oct; 20(10):102899.
journal title abbreviation: Autoimmun Rev
publication date: 2021-07-15T00:00:00
year: 2021
type: Academic Article
type: Article
type: Document
type: Information Resource

Reliability of digital ulcer definitions as proposed by the UK Scleroderma Study Group: A challenge for clinical trial design.
PubMed Identifier: 29876526
author list: Hughes M, Tracey A, Bhushan M, Chakravarty K, Denton CP, Dubey S, Guiducci S, Muir L, Ong V, Parker L, Pauling JD, Prabu A, Rogers C, Roberts C, Herrick AL
published in: Journal of scleroderma and related disorders
information resource reference: Reliability of digital ulcer definitions as proposed by the UK Scleroderma Study Group: A challenge for clinical trial design. J Scleroderma Relat Disord. 2018 Jun 01; 3(2):170-174.
journal title abbreviation: J Scleroderma Relat Disord
publication date: 2018-03-27T00:00:00
year: 2018
type: Academic Article
type: Article
type: Document
type: Information Resource

https://connects.catalyst.harvard.edu/Profiles/profile/194565592
PubMed Identifier: 25732174
author list: Hughes M, Lilleker JB, Herrick AL, Chinoy H
published in: Annals of the rheumatic diseases
information resource reference: Cardiac troponin testing in idiopathic inflammatory myopathies and systemic sclerosis-spectrum disorders: biomarkers to distinguish between primary cardiac involvement and low-grade skeletal muscle disease activity. Ann Rheum Dis. 2015 May; 74(5):795-8.
journal title abbreviation: Ann Rheum Dis
publication date: 2015-03-02T00:00:00
year: 2015
type: Academic Article
type: Article
type: Document
type: Information Resource
label: Cardiac troponin testing in idiopathic inflammatory myopathies and systemic sclerosis-spectrum disorders: biomarkers to distinguish between primary cardiac involvement and low-grade skeletal muscle disease activity.

Raynaud's phenomenon.
PubMed Identifier: 27421220
author list: Hughes M, Herrick AL
published in: Best practice & research. Clinical rheumatology
information resource reference: Raynaud's phenomenon. Best Pract Res Clin Rheumatol. 2016 02; 30(1):112-32.
journal title abbreviation: Best Pract Res Clin Rheumatol
publication date: 2016-05-11T00:00:00
year: 2016
type: Academic Article
type: Article
type: Document
type: Information Resource

Haemoglobinopathies and the rheumatologist.
PubMed Identifier: 27018056
author list: Hughes M, Akram Q, Rees DC, Jones AK
published in: Rheumatology (Oxford, England)
information resource reference: Haemoglobinopathies and the rheumatologist. Rheumatology (Oxford). 2016 Dec; 55(12):2109-2118.
journal title abbreviation: Rheumatology (Oxford)
publication date: 2016-03-27T00:00:00
year: 2016
type: Academic Article
type: Article
type: Document
type: Information Resource

Should all digital ulcers be included in future clinical trials of systemic sclerosis-related digital vasculopathy?
PubMed Identifier: 29857890
author list: Hughes M, Murray A, Denton CP, Herrick AL
published in: Medical hypotheses
information resource reference: Should all digital ulcers be included in future clinical trials of systemic sclerosis-related digital vasculopathy? Med Hypotheses. 2018 Jul; 116:101-104.
journal title abbreviation: Med Hypotheses
publication date: 2018-05-02T00:00:00
year: 2018
type: Academic Article
type: Article
type: Document
type: Information Resource

A pilot study using high-frequency ultrasound to measure digital ulcers: a possible outcome measure in systemic sclerosis clinical trials?
PubMed Identifier: 28598784
author list: Hughes M, Moore T, Manning J, Dinsdale G, Herrick AL, Murray A
published in: Clinical and experimental rheumatology
information resource reference: A pilot study using high-frequency ultrasound to measure digital ulcers: a possible outcome measure in systemic sclerosis clinical trials? Clin Exp Rheumatol. 2017 Sep-Oct; 35 Suppl 106(4):218-219.
journal title abbreviation: Clin Exp Rheumatol
publication date: 2017-06-07T00:00:00
year: 2017
type: Academic Article
type: Article
type: Document
type: Information Resource

Imaging calcinosis in patients with systemic sclerosis by radiography, computerised tomography and magnetic resonance imaging.
PubMed Identifier: 30981516
author list: Hughes M, Hodgson R, Harris J, Porter N, Jackson S, Kirwadi A, Manning J, Peytrignet S, Herrick AL
published in: Seminars in arthritis and rheumatism
information resource reference: Imaging calcinosis in patients with systemic sclerosis by radiography, computerised tomography and magnetic resonance imaging. Semin Arthritis Rheum. 2019 10; 49(2):279-282.
journal title abbreviation: Semin Arthritis Rheum
publication date: 2019-03-09T00:00:00
year: 2019
type: Academic Article
type: Article
type: Document
type: Information Resource

Further evidence that calcinosis is associated with repetitive trauma in systemic sclerosis.
PubMed Identifier: 31353058
author list: Hughes M, Hodgson R, Harris J, Porter N, Jackson S, Kirwadi A, Manning J, Peytrignet S, Herrick AL
published in: Seminars in arthritis and rheumatism
information resource reference: Further evidence that calcinosis is associated with repetitive trauma in systemic sclerosis. Semin Arthritis Rheum. 2020 02; 50(1):E4-E5.
journal title abbreviation: Semin Arthritis Rheum
publication date: 2019-07-08T00:00:00
year: 2019
type: Academic Article
type: Article
type: Document
type: Information Resource

Force adaptive robotically assisted endomicroscopy for intraoperative tumour identification.
PubMed Identifier: 25900339
author list: Giataganas P, Hughes M, Yang GZ
published in: International journal of computer assisted radiology and surgery
information resource reference: Force adaptive robotically assisted endomicroscopy for intraoperative tumour identification. Int J Comput Assist Radiol Surg. 2015 Jun; 10(6):825-32.
journal title abbreviation: Int J Comput Assist Radiol Surg
publication date: 2015-04-23T00:00:00
year: 2015
type: Academic Article
type: Article
type: Document
type: Information Resource

Digital ulcers in systemic sclerosis.
PubMed Identifier: 27094599
author list: Hughes M, Herrick AL
published in: Rheumatology (Oxford, England)
information resource reference: Digital ulcers in systemic sclerosis. Rheumatology (Oxford). 2017 01; 56(1):14-25.
journal title abbreviation: Rheumatology (Oxford)
publication date: 2016-04-19T00:00:00
year: 2016
type: Academic Article
type: Article
type: Document
type: Information Resource

High Prevalence of Tuberculosis Infection and Disease in Child Household Contacts of Adults With Rifampin-resistant Tuberculosis.
PubMed Identifier: 35239624
author list: Kim S, Wu X, Hughes MD, Upton C, Narunsky K, Mendoza-Ticona A, Khajenoori S, Gonzales P, Badal-Faesen S, Shenje J, Omoz-Oarhe A, Rouzier V, Garcia-Prats AJ, Demers AM, Naini L, Smith E, Churchyard G, Swindells S, Shah NS, Gupta A, Hesseling AC
published in: The Pediatric infectious disease journal
information resource reference: High Prevalence of Tuberculosis Infection and Disease in Child Household Contacts of Adults With Rifampin-resistant Tuberculosis. Pediatr Infect Dis J. 2022 05 01; 41(5):e194-e202.
journal title abbreviation: Pediatr Infect Dis J
publication date: 2022-05-01T00:00:00
year: 2022
type: Academic Article
type: Article
type: Document
type: Information Resource

Monoclonal antibody treatment drives rapid culture conversion in SARS-CoV-2 infection.
PubMed Identifier: 35793677
author list: Boucau J, Chew KW, Choudhary MC, Deo R, Regan J, Flynn JP, Crain CR, Hughes MD, Ritz J, Moser C, Dragavon JA, Javan AC, Nirula A, Klekotka P, Greninger AL, Coombs RW, Fischer WA, Daar ES, Wohl DA, Eron JJ, Currier JS, Smith DM, Li JZ, Barczak AK
published in: Cell reports. Medicine
information resource reference: Monoclonal antibody treatment drives rapid culture conversion in SARS-CoV-2 infection. Cell Rep Med. 2022 07 19; 3(7):100678.
journal title abbreviation: Cell Rep Med
publication date: 2022-06-20T00:00:00
year: 2022
type: Academic Article
type: Article
type: Document
type: Information Resource

Antiviral and clinical activity of bamlanivimab in a randomized trial of non-hospitalized adults with COVID-19.
PubMed Identifier: 35995785
author list: Chew KW, Moser C, Daar ES, Wohl DA, Li JZ, Coombs RW, Ritz J, Giganti M, Javan AC, Li Y, Choudhary MC, Deo R, Malvestutto C, Klekotka P, Price K, Nirula A, Fischer W, Bala V, Ribeiro RM, Perelson AS, Fletcher CV, Eron JJ, Currier JS, Hughes MD, Smith DM
published in: Nature communications
information resource reference: Antiviral and clinical activity of bamlanivimab in a randomized trial of non-hospitalized adults with COVID-19. Nat Commun. 2022 08 22; 13(1):4931.
journal title abbreviation: Nat Commun
publication date: 2022-08-22T00:00:00
year: 2022
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1468489
type: Authorship
author rank in publication: 7
linked author: Hughes, Michael
linked information resource: Comparative Pharmacokinetics of Tixagevimab/Cilgavimab (AZD7442) Administered Intravenously Versus Intramuscularly in Symptomatic SARS-CoV-2 Infection.

Authorship 1461749
type: Authorship
author rank in publication: 4
linked author: Hughes, Michael
linked information resource: The case for altruism in institutional diagnostic testing.

Authorship 1459550
type: Authorship
author rank in publication: 18
linked author: Hughes, Michael
linked information resource: Immune correlates of HIV-1 reservoir cell decline in early-treated infants.

Authorship 1468195
type: Authorship
author rank in publication: 8
linked author: Hughes, Michael
linked information resource: Monoclonal antibody treatment drives rapid culture conversion in SARS-CoV-2 infection.

Comparative Pharmacokinetics of Tixagevimab/Cilgavimab (AZD7442) Administered Intravenously Versus Intramuscularly in Symptomatic SARS-CoV-2 Infection.
PubMed Identifier: 35797235
author list: Bender Ignacio RA, Wohl DA, Arends R, Pilla Reddy V, Mu Y, Javan AC, Hughes MD, Eron JJ, Currier JS, Smith D, Chew KW, Gibbs M, Fletcher CV
published in: Clinical pharmacology and therapeutics
information resource reference: Comparative Pharmacokinetics of Tixagevimab/Cilgavimab (AZD7442) Administered Intravenously Versus Intramuscularly in Symptomatic SARS-CoV-2 Infection. Clin Pharmacol Ther. 2022 12; 112(6):1207-1213.
journal title abbreviation: Clin Pharmacol Ther
publication date: 2022-07-26T00:00:00
year: 2022
type: Academic Article
type: Article
type: Document
type: Information Resource

Immune correlates of HIV-1 reservoir cell decline in early-treated infants.
PubMed Identifier: 35858580
author list: Hartana CA, Garcia-Broncano P, Rassadkina Y, Lian X, Jiang C, Einkauf KB, Maswabi K, Ajibola G, Moyo S, Mohammed T, Maphorisa C, Makhema J, Yuki Y, Martin M, Bennett K, Jean-Philippe P, Viard M, Hughes MD, Powis KM, Carrington M, Lockman S, Gao C, Yu XG, Kuritzkes DR, Shapiro R, Lichterfeld M
published in: Cell reports
information resource reference: Immune correlates of HIV-1 reservoir cell decline in early-treated infants. Cell Rep. 2022 07 19; 40(3):111126.
journal title abbreviation: Cell Rep
publication date: 2022-07-19T00:00:00
year: 2022
type: Academic Article
type: Article
type: Document
type: Information Resource

Emergence of SARS-CoV-2 escape mutations during Bamlanivimab therapy in a phase II randomized clinical trial.
PubMed Identifier: 36289399
author list: Choudhary MC, Chew KW, Deo R, Flynn JP, Regan J, Crain CR, Moser C, Hughes MD, Ritz J, Ribeiro RM, Ke R, Dragavon JA, Javan AC, Nirula A, Klekotka P, Greninger AL, Fletcher CV, Daar ES, Wohl DA, Eron JJ, Currier JS, Parikh UM, Sieg SF, Perelson AS, Coombs RW, Smith DM, Li JZ
published in: Nature microbiology
information resource reference: Emergence of SARS-CoV-2 escape mutations during Bamlanivimab therapy in a phase II randomized clinical trial. Nat Microbiol. 2022 11; 7(11):1906-1917.
journal title abbreviation: Nat Microbiol
publication date: 2022-10-26T00:00:00
year: 2022
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1486660
type: Authorship
author rank in publication: 8
linked author: Hughes, Michael
linked information resource: 'I turned in my man card': a qualitative study of the experiences, coping styles and support needs of men with systemic sclerosis.

Authorship 1477294
type: Authorship
author rank in publication: 10
linked author: Hughes, Michael
linked information resource: Viral and Symptom Rebound in Untreated COVID-19 Infection.

Authorship 1501501
type: Authorship
author rank in publication: 1
linked author: Hughes, Michael
linked information resource: https://connects.catalyst.harvard.edu/Profiles/profile/203402765

Authorship 1480597
type: Authorship
author rank in publication: 10
linked author: Hughes, Michael
linked information resource: Safety and Pharmacokinetics of Intravenous 10-1074 and VRC01LS in Young Children.

Authorship 1498374
type: Authorship
author rank in publication: 4
linked author: Hughes, Michael
linked information resource: Hedgehog Signaling as a Therapeutic Target for Airway Remodeling and Inflammation in Allergic Asthma.

Authorship 1489590
type: Authorship
author rank in publication: 8
linked author: Hughes, Michael
linked information resource: Emergence of SARS-CoV-2 escape mutations during Bamlanivimab therapy in a phase II randomized clinical trial.

Authorship 1498795
type: Authorship
author rank in publication: 3
linked author: Hughes, Michael
linked information resource: Iron status among HIV-infected adults during the first year of antiretroviral therapy in Tanzania.

Authorship 1488057
type: Authorship
author rank in publication: 14
linked author: Hughes, Michael
linked information resource: https://connects.catalyst.harvard.edu/Profiles/profile/203406128

Authorship 1489093
type: Authorship
author rank in publication: 10
linked author: Hughes, Michael
linked information resource: Multimodal surveillance of SARS-CoV-2 at a university enables development of a robust outbreak response framework.

Authorship 1488827
type: Authorship
author rank in publication: 2
linked author: Hughes, Michael
linked information resource: Statistical methodologies for evaluation of the rate of persistence of Ebola virus in semen of male survivors in Sierra Leone.

Authorship 1490604
type: Authorship
author rank in publication: 7
linked author: Hughes, Michael
linked information resource: Recurrence of Symptoms Following a 2-Day Symptom Free Period in Patients With COVID-19.

Authorship 1473684
type: Authorship
author rank in publication: 4
linked author: Hughes, Michael
linked information resource: Evo-Devo of amniote integuments and appendages.

Authorship 1498363
type: Authorship
author rank in publication: 2
linked author: Hughes, Michael
linked information resource: https://connects.catalyst.harvard.edu/Profiles/profile/203405320

Authorship 1493147
type: Authorship
author rank in publication: 25
linked author: Hughes, Michael
linked information resource: Antiviral and clinical activity of bamlanivimab in a randomized trial of non-hospitalized adults with COVID-19.

Authorship 1500282
type: Authorship
author rank in publication: 2
linked author: Hughes, Michael
linked information resource: The effect of iron supplementation on maternal iron deficiency anemia does not differ by baseline anemia type among Tanzanian pregnant women without severe iron deficiency anemia.

Iron status among HIV-infected adults during the first year of antiretroviral therapy in Tanzania.
PubMed Identifier: 36075691
author list: Abioye AI, Sudfeld CR, Hughes MD, Aboud S, Muhihi A, Ulenga N, Nagu TJ, Wang M, Mugusi F, Fawzi WW
published in: HIV medicine
information resource reference: Iron status among HIV-infected adults during the first year of antiretroviral therapy in Tanzania. HIV Med. 2023 04; 24(4):398-410.
journal title abbreviation: HIV Med
publication date: 2022-09-08T00:00:00
year: 2022
type: Academic Article
type: Article
type: Document
type: Information Resource

Multimodal surveillance of SARS-CoV-2 at a university enables development of a robust outbreak response framework.
PubMed Identifier: 36198312
author list: Petros BA, Paull JS, Tomkins-Tinch CH, Loftness BC, DeRuff KC, Nair P, Gionet GL, Benz A, Brock-Fisher T, Hughes M, Yurkovetskiy L, Mulaudzi S, Leenerman E, Nyalile T, Moreno GK, Specht I, Sani K, Adams G, Babet SV, Baron E, Blank JT, Boehm C, Botti-Lodovico Y, Brown J, Buisker AR, Burcham T, Chylek L, Cronan P, Dauphin A, Desreumaux V, Doss M, Flynn B, Gladden-Young A, Glennon O, Harmon HD, Hook TV, Kary A, King C, Loreth C, Marrs L, McQuade KJ, Milton TT, Mulford JM, Oba K, Pearlman L, Schifferli M, Schmidt MJ, Tandus GM, Tyler A, Vodzak ME, Krohn Bevill K, Colubri A, MacInnis BL, Ozsoy AZ, Parrie E, Sholtes K, Siddle KJ, Fry B, Luban J, Park DJ, Marshall J, Bronson A, Schaffner SF, Sabeti PC
published in: Med (New York, N.Y.)
information resource reference: Multimodal surveillance of SARS-CoV-2 at a university enables development of a robust outbreak response framework. Med. 2022 Dec 09; 3(12):883-900.e13.
journal title abbreviation: Med
publication date: 2022-09-19T00:00:00
year: 2022
type: Academic Article
type: Article
type: Document
type: Information Resource

Viral and Symptom Rebound in Untreated COVID-19 Infection.
PubMed Identifier: 35982660
author list: Deo R, Choudhary MC, Moser C, Ritz J, Daar ES, Wohl DA, Greninger AL, Eron JJ, Currier JS, Hughes MD, Smith DM, Chew KW, Li JZ
published in: medRxiv : the preprint server for health sciences
information resource reference: Viral and Symptom Rebound in Untreated COVID-19 Infection. medRxiv. 2022 Aug 02.
journal title abbreviation: medRxiv
publication date: 2022-08-02T00:00:00
year: 2022
type: Academic Article
type: Article
type: Document
type: Information Resource

Hedgehog Signaling as a Therapeutic Target for Airway Remodeling and Inflammation in Allergic Asthma.
PubMed Identifier: 36230980
author list: Tam A, Osei ET, Cheung CY, Hughes M, Yang CX, McNagny KM, Dorscheid DR, Singhera GK, Hallstrand TS, Warner S, Hogg JC, Hackett TL, Lim CJ, Sin DD
published in: Cells
information resource reference: Hedgehog Signaling as a Therapeutic Target for Airway Remodeling and Inflammation in Allergic Asthma. Cells. 2022 09 27; 11(19).
journal title abbreviation: Cells
publication date: 2022-09-27T00:00:00
year: 2022
type: Academic Article
type: Article
type: Document
type: Information Resource

Evo-Devo of amniote integuments and appendages.
PubMed Identifier: 15272390
author list: Wu P, Hou L, Plikus M, Hughes M, Scehnet J, Suksaweang S, Widelitz R, Jiang TX, Chuong CM
published in: The International journal of developmental biology
information resource reference: Evo-Devo of amniote integuments and appendages. Int J Dev Biol. 2004; 48(2-3):249-70.
journal title abbreviation: Int J Dev Biol
publication date: 2004-01-01T00:00:00
year: 2004
type: Academic Article
type: Article
type: Document
type: Information Resource

Recurrence of Symptoms Following a 2-Day Symptom Free Period in Patients With COVID-19.
PubMed Identifier: 36301549
author list: Smith DM, Li JZ, Moser C, Yeh E, Currier JS, Chew KW, Hughes MD
published in: JAMA network open
information resource reference: Recurrence of Symptoms Following a 2-Day Symptom Free Period in Patients With COVID-19. JAMA Netw Open. 2022 10 03; 5(10):e2238867.
journal title abbreviation: JAMA Netw Open
publication date: 2022-10-03T00:00:00
year: 2022
type: Academic Article
type: Article
type: Document
type: Information Resource

https://connects.catalyst.harvard.edu/Profiles/profile/203402765
PubMed Identifier: 36356481
author list: Hughes M, Umair HM, Sandler RD, Alunno A, Matucci-Cerinic M
published in: Seminars in arthritis and rheumatism
information resource reference: Harnessing the therapeutic potential therapeutic efficacy of a-1 adrenergic blockers for Raynaud's phenomenon and digital ischaemia secondary to central nervous system stimulants used for attention deficit hyperactivity disorder. Semin Arthritis Rheum. 2022 12; 57:152114.
journal title abbreviation: Semin Arthritis Rheum
publication date: 2022-10-21T00:00:00
year: 2022
type: Academic Article
type: Article
type: Document
type: Information Resource
label: Harnessing the therapeutic potential therapeutic efficacy of a-1 adrenergic blockers for Raynaud's phenomenon and digital ischaemia secondary to central nervous system stimulants used for attention deficit hyperactivity disorder.

https://connects.catalyst.harvard.edu/Profiles/profile/203405320
PubMed Identifier: 36039892
author list: Avihingsanon A, Hughes MD, Salata R, Godfrey C, McCarthy C, Mugyenyi P, Hogg E, Gross R, Cardoso SW, Bukuru A, Makanga M, Badal-Aesen S, Mave V, Ndege BW, Fontain SN, Samaneka W, Secours R, Van Schalkwyk M, Mngqibisa R, Mohapi L, Valencia J, Sugandhavesa P, Montalban E, Munyanga C, Chagomerana M, Santos BR, Kumarasamy N, Kanyama C, Schooley RT, Mellors JW, Wallis CL, Collier AC, Grinsztejn B
published in: Journal of the International AIDS Society
information resource reference: Third-line antiretroviral therapy, including raltegravir (RAL), darunavir (DRV/r) and/or etravirine (ETR), is well tolerated and achieves durable virologic suppression over 144 weeks in resource-limited settings: ACTG A5288 strategy trial. J Int AIDS Soc. 2022 06; 25(6):e25905.
journal title abbreviation: J Int AIDS Soc
publication date: 2022-06-01T00:00:00
year: 2022
type: Academic Article
type: Article
type: Document
type: Information Resource
label: Third-line antiretroviral therapy, including raltegravir (RAL), darunavir (DRV/r) and/or etravirine (ETR), is well tolerated and achieves durable virologic suppression over 144 weeks in resource-limited settings: ACTG A5288 strategy trial.

https://connects.catalyst.harvard.edu/Profiles/profile/203406128
PubMed Identifier: 36210483
author list: Li Y, Harrison LJ, Chew KW, Currier JS, Wohl DA, Daar ES, Evering TH, Wu R, Giganti M, Ritz J, Javan AC, Coombs RW, Moser C, Hughes MD, Eron JJ, Smith DM, Li JZ
published in: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
information resource reference: Nasal and Plasma Severe Acute Respiratory Syndrome Coronavirus 2 RNA Levels Are Associated With Timing of Symptom Resolution in the ACTIV-2 Trial of Nonhospitalized Adults With Coronavirus Disease 2019. Clin Infect Dis. 2023 02 18; 76(4):734-737.
journal title abbreviation: Clin Infect Dis
publication date: 2023-02-18T00:00:00
year: 2023
type: Academic Article
type: Article
type: Document
type: Information Resource
label: Nasal and Plasma Severe Acute Respiratory Syndrome Coronavirus 2 RNA Levels Are Associated With Timing of Symptom Resolution in the ACTIV-2 Trial of Nonhospitalized Adults With Coronavirus Disease 2019.

The effect of iron supplementation on maternal iron deficiency anemia does not differ by baseline anemia type among Tanzanian pregnant women without severe iron deficiency anemia.
PubMed Identifier: 36344770
author list: Abioye AI, Hughes MD, Sudfeld CR, Premji Z, Aboud S, Hamer DH, Roberts DJ, Duggan CP, Fawzi WW
published in: European journal of nutrition
information resource reference: The effect of iron supplementation on maternal iron deficiency anemia does not differ by baseline anemia type among Tanzanian pregnant women without severe iron deficiency anemia. Eur J Nutr. 2023 Mar; 62(2):987-1001.
journal title abbreviation: Eur J Nutr
publication date: 2022-11-08T00:00:00
year: 2022
type: Academic Article
type: Article
type: Document
type: Information Resource

'I turned in my man card': a qualitative study of the experiences, coping styles and support needs of men with systemic sclerosis.
PubMed Identifier: 36205545
author list: Flurey CA, Pauling JD, Saketkoo LA, Denton CP, Galdas P, Khanna D, Williams A, Hughes M
published in: Rheumatology (Oxford, England)
information resource reference: 'I turned in my man card': a qualitative study of the experiences, coping styles and support needs of men with systemic sclerosis. Rheumatology (Oxford). 2023 06 01; 62(6):2160-2167.
journal title abbreviation: Rheumatology (Oxford)
publication date: 2023-06-01T00:00:00
year: 2023
type: Academic Article
type: Article
type: Document
type: Information Resource

Safety and Pharmacokinetics of Intravenous 10-1074 and VRC01LS in Young Children.
PubMed Identifier: 36094485
author list: Capparelli EV, Ajibola G, Maswabi K, Holme MP, Bennett K, Powis KM, Moyo S, Mohammed T, Maphorisa C, Hughes MD, Seaton KE, Tomaras GD, Mosher S, Taylor A, O'Connell S, Narpala S, Mcdermott A, Caskey M, Gama L, Lockman S, Jean-Philippe P, Makhema J, Kuritzkes DR, Lichterfeld M, Shapiro RL
published in: Journal of acquired immune deficiency syndromes (1999)
information resource reference: Safety and Pharmacokinetics of Intravenous 10-1074 and VRC01LS in Young Children. J Acquir Immune Defic Syndr. 2022 10 01; 91(2):182-188.
journal title abbreviation: J Acquir Immune Defic Syndr
publication date: 2022-10-01T00:00:00
year: 2022
type: Academic Article
type: Article
type: Document
type: Information Resource

Statistical methodologies for evaluation of the rate of persistence of Ebola virus in semen of male survivors in Sierra Leone.
PubMed Identifier: 36197875
author list: Habib N, Hughes MD, Broutet N, Thorson A, Gaillard P, Landoulsi S, McDonald SLR, Formenty P
published in: PloS one
information resource reference: Statistical methodologies for evaluation of the rate of persistence of Ebola virus in semen of male survivors in Sierra Leone. PLoS One. 2022; 17(10):e0274755.
journal title abbreviation: PLoS One
publication date: 2022-10-05T00:00:00
year: 2022
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1504875
type: Authorship
author rank in publication: 16
linked author: Hughes, Michael
linked information resource: Bamlanivimab therapy for acute COVID-19 does not blunt SARS-CoV-2-specific memory T cell responses.

Bamlanivimab therapy for acute COVID-19 does not blunt SARS-CoV-2-specific memory T cell responses.
PubMed Identifier: 36378539
author list: Ramirez SI, Grifoni A, Weiskopf D, Parikh UM, Heaps A, Faraji F, Sieg SF, Ritz J, Moser C, Eron JJ, Currier JS, Klekotka P, Sette A, Wohl DA, Daar ES, Hughes MD, Chew KW, Smith DM, Crotty S
published in: JCI insight
information resource reference: Bamlanivimab therapy for acute COVID-19 does not blunt SARS-CoV-2-specific memory T cell responses. JCI Insight. 2022 12 22; 7(24).
journal title abbreviation: JCI Insight
publication date: 2022-12-22T00:00:00
year: 2022
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1509100
type: Authorship
author rank in publication: 14
linked author: Hughes, Michael
linked information resource: Predictors of SARS-CoV-2 RNA From Nasopharyngeal Swabs and Concordance With Other Compartments in Nonhospitalized Adults With Mild to Moderate COVID-19.

Predictors of SARS-CoV-2 RNA From Nasopharyngeal Swabs and Concordance With Other Compartments in Nonhospitalized Adults With Mild to Moderate COVID-19.
PubMed Identifier: 36467293
author list: Moser C, Li JZ, Eron JJ, Aga E, Daar ES, Wohl DA, Coombs RW, Javan AC, Bender Ignacio RA, Jagannathan P, Ritz J, Sieg SF, Parikh UM, Hughes MD, Currier JS, Smith DM, Chew KW
published in: Open forum infectious diseases
information resource reference: Predictors of SARS-CoV-2 RNA From Nasopharyngeal Swabs and Concordance With Other Compartments in Nonhospitalized Adults With Mild to Moderate COVID-19. Open Forum Infect Dis. 2022 Nov; 9(11):ofac618.
journal title abbreviation: Open Forum Infect Dis
publication date: 2022-11-11T00:00:00
year: 2022
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1514660
type: Authorship
author rank in publication: 19
linked author: Hughes, Michael
linked information resource: Hydroxychloroquine for treatment of non-hospitalized adults with COVID-19: A meta-analysis of individual participant data of randomized trials.

Authorship 1514815
type: Authorship
author rank in publication: 12
linked author: Hughes, Michael
linked information resource: Predictors of virologic outcome among people living with HIV who continue a protease inhibitor-based antiretroviral regimen following virologic failure with no or limited resistance.

Hydroxychloroquine for treatment of non-hospitalized adults with COVID-19: A meta-analysis of individual participant data of randomized trials.
PubMed Identifier: 36601684
author list: Mitjà O, Reis G, Boulware DR, Spivak AM, Sarwar A, Johnston C, Webb B, Hill MD, Smith D, Kremsner P, Curran M, Carter D, Alexander J, Corbacho M, Lee TC, Hullsiek KH, McDonald EG, Hess R, Hughes M, Baeten JM, Schwartz I, Metz L, Richer L, Chew KW, Daar E, Wohl D, Dunne M
published in: Clinical and translational science
information resource reference: Hydroxychloroquine for treatment of non-hospitalized adults with COVID-19: A meta-analysis of individual participant data of randomized trials. Clin Transl Sci. 2023 03; 16(3):524-535.
journal title abbreviation: Clin Transl Sci
publication date: 2023-01-04T00:00:00
year: 2023
type: Academic Article
type: Article
type: Document
type: Information Resource

Predictors of virologic outcome among people living with HIV who continue a protease inhibitor-based antiretroviral regimen following virologic failure with no or limited resistance.
PubMed Identifier: 36604746
author list: Salata RA, Grinsztejn B, Ritz J, Collier AC, Hogg E, Gross R, Godfrey C, Kumarasamy N, Kanyama C, Mellors JW, Wallis CL, Hughes MD
published in: AIDS research and therapy
information resource reference: Predictors of virologic outcome among people living with HIV who continue a protease inhibitor-based antiretroviral regimen following virologic failure with no or limited resistance. AIDS Res Ther. 2023 01 05; 20(1):3.
journal title abbreviation: AIDS Res Ther
publication date: 2023-01-05T00:00:00
year: 2023
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1517614
type: Authorship
author rank in publication: 25
linked author: Hughes, Michael
linked information resource: Publisher Correction: Antiviral and clinical activity of bamlanivimab in a randomized trial of non-hospitalized adults with COVID-19.

Authorship 1516343
type: Authorship
author rank in publication: 18
linked author: Hughes, Michael
linked information resource: Phase 2 Safety and Antiviral Activity of SAB-185, a Novel Polyclonal Antibody Therapy for Nonhospitalized Adults With COVID-19.

Phase 2 Safety and Antiviral Activity of SAB-185, a Novel Polyclonal Antibody Therapy for Nonhospitalized Adults With COVID-19.
PubMed Identifier: 36661240
author list: Taiwo BO, Chew KW, Moser C, Wohl DA, Daar ES, Li JZ, Greninger AL, Bausch C, Luke T, Hoover K, Neytman G, Giganti MJ, Olefsky M, Javan AC, Fletcher CV, Eron JJ, Currier JS, Hughes MD, Smith DM
published in: The Journal of infectious diseases
information resource reference: Phase 2 Safety and Antiviral Activity of SAB-185, a Novel Polyclonal Antibody Therapy for Nonhospitalized Adults With COVID-19. J Infect Dis. 2023 07 14; 228(2):133-142.
journal title abbreviation: J Infect Dis
publication date: 2023-07-14T00:00:00
year: 2023
type: Academic Article
type: Article
type: Document
type: Information Resource

Publisher Correction: Antiviral and clinical activity of bamlanivimab in a randomized trial of non-hospitalized adults with COVID-19.
PubMed Identifier: 36658128
author list: Chew KW, Moser C, Daar ES, Wohl DA, Li JZ, Coombs RW, Ritz J, Giganti M, Javan AC, Li Y, Choudhary MC, Deo R, Malvestutto C, Klekotka P, Price K, Nirula A, Fischer W, Bala V, Ribeiro RM, Perelson AS, Fletcher CV, Eron JJ, Currier JS, Hughes MD, Smith DM
published in: Nature communications
information resource reference: Publisher Correction: Antiviral and clinical activity of bamlanivimab in a randomized trial of non-hospitalized adults with COVID-19. Nat Commun. 2023 Jan 19; 14(1):333.
journal title abbreviation: Nat Commun
publication date: 2023-01-19T00:00:00
year: 2023
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1521775
type: Authorship
author rank in publication: 3
linked author: Hughes, Michael
linked information resource: Brief Report: Long-Term Clinical, Immunologic, and Virologic Outcomes Among Early-Treated Children With HIV in Botswana: A Nonrandomized Controlled Clinical Trial.

Authorship 1522293
type: Authorship
author rank in publication: 7
linked author: Hughes, Michael
linked information resource: Qualitative interviews to evaluate content validity of the ACTIV-2 COVID-19 Symptom Diary (ACSD).

Brief Report: Long-Term Clinical, Immunologic, and Virologic Outcomes Among Early-Treated Children With HIV in Botswana: A Nonrandomized Controlled Clinical Trial.
PubMed Identifier: 36729692
author list: Ajibola G, Maswabi K, Hughes MD, Bennett K, Pretorius-Holme M, Capparelli EV, Jean-Philippe P, Moyo S, Mohammed T, Batlang O, Sakoi M, Ricci L, Lockman S, Makhema J, Kuritzkes DR, Lichterfeld M, Shapiro RL
published in: Journal of acquired immune deficiency syndromes (1999)
information resource reference: Brief Report: Long-Term Clinical, Immunologic, and Virologic Outcomes Among Early-Treated Children With HIV in Botswana: A Nonrandomized Controlled Clinical Trial. J Acquir Immune Defic Syndr. 2023 04 15; 92(5):393-398.
journal title abbreviation: J Acquir Immune Defic Syndr
publication date: 2023-04-15T00:00:00
year: 2023
type: Academic Article
type: Article
type: Document
type: Information Resource

Qualitative interviews to evaluate content validity of the ACTIV-2 COVID-19 Symptom Diary (ACSD).
PubMed Identifier: 36719546
author list: Matza LS, Stewart KD, Naegeli AN, Mills KM, Coyne KS, Chew KW, Hughes MD, Smith DM
published in: Journal of patient-reported outcomes
information resource reference: Qualitative interviews to evaluate content validity of the ACTIV-2 COVID-19 Symptom Diary (ACSD). J Patient Rep Outcomes. 2023 01 31; 7(1):8.
journal title abbreviation: J Patient Rep Outcomes
publication date: 2023-01-31T00:00:00
year: 2023
type: Academic Article
type: Article
type: Document
type: Information Resource

Differential associations of leptin with adiposity across early childhood.
PubMed Identifier: 23408391
author list: Boeke CE, Mantzoros CS, Hughes MD, L Rifas-Shiman S, Villamor E, Zera CA, Gillman MW
published in: Obesity (Silver Spring, Md.)
information resource reference: Differential associations of leptin with adiposity across early childhood. Obesity (Silver Spring). 2013 Jul; 21(7):1430-7.
journal title abbreviation: Obesity (Silver Spring)
publication date: 2013-05-25T00:00:00
year: 2013
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1524323
type: Authorship
author rank in publication: 10
linked author: Hughes, Michael
linked information resource: Symptom and Viral Rebound in Untreated SARS-CoV-2 Infection.

Symptom and Viral Rebound in Untreated SARS-CoV-2 Infection.
PubMed Identifier: 36802755
author list: Deo R, Choudhary MC, Moser C, Ritz J, Daar ES, Wohl DA, Greninger AL, Eron JJ, Currier JS, Hughes MD, Smith DM, Chew KW, Li JZ
published in: Annals of internal medicine
information resource reference: Symptom and Viral Rebound in Untreated SARS-CoV-2 Infection. Ann Intern Med. 2023 03; 176(3):348-354.
journal title abbreviation: Ann Intern Med
publication date: 2023-02-21T00:00:00
year: 2023
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1531171
type: Authorship
author rank in publication: 4
linked author: Hughes, Michael
linked information resource: Factors associated with prevalent Mycobacterium tuberculosis infection and disease among adolescents and adults exposed to rifampin-resistant tuberculosis in the household.

Factors associated with prevalent Mycobacterium tuberculosis infection and disease among adolescents and adults exposed to rifampin-resistant tuberculosis in the household.
PubMed Identifier: 36930628
author list: Kim S, Hesseling AC, Wu X, Hughes MD, Shah NS, Gaikwad S, Kumarasamy N, Mitchell E, Leon M, Gonzales P, Badal-Faesen S, Lourens M, Nerette S, Shenje J, de Koker P, Nedsuwan S, Mohapi L, Chakalisa UA, Mngqbisa R, Escada RODS, Ouma S, Heckman B, Naini L, Gupta A, Swindells S, Churchyard G
published in: PloS one
information resource reference: Factors associated with prevalent Mycobacterium tuberculosis infection and disease among adolescents and adults exposed to rifampin-resistant tuberculosis in the household. PLoS One. 2023; 18(3):e0283290.
journal title abbreviation: PLoS One
publication date: 2023-03-17T00:00:00
year: 2023
type: Academic Article
type: Article
type: Document
type: Information Resource

Safety and Efficacy of Combination SARS-CoV-2 Neutralizing Monoclonal Antibodies Amubarvimab Plus Romlusevimab in Nonhospitalized Patients With COVID-19.
PubMed Identifier: 37068272
author list: Evering TH, Chew KW, Giganti MJ, Moser C, Pinilla M, Wohl DA, Currier JS, Eron JJ, Javan AC, Bender Ignacio R, Margolis D, Zhu Q, Ma J, Zhong L, Yan L, D'Andrea Nores U, Hoover K, Mocherla B, Choudhary MC, Deo R, Ritz J, Fischer WA, Fletcher CV, Li JZ, Hughes MD, Smith D, Daar ES
published in: Annals of internal medicine
information resource reference: Safety and Efficacy of Combination SARS-CoV-2 Neutralizing Monoclonal Antibodies Amubarvimab Plus Romlusevimab in Nonhospitalized Patients With COVID-19. Ann Intern Med. 2023 05; 176(5):658-666.
journal title abbreviation: Ann Intern Med
publication date: 2023-04-18T00:00:00
year: 2023
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 192222
type: Authorship
author rank in publication: 2
linked author: Hughes, Michael
linked information resource: Subtle decreases in stavudine phenotypic susceptibility predict poor virologic response to stavudine monotherapy in zidovudine-experienced patients.

One Week of Oral Camostat Versus Placebo in Nonhospitalized Adults With Mild-to-Moderate Coronavirus Disease 2019: A Randomized Controlled Phase 2 Trial.
PubMed Identifier: 37279602
author list: Jilg N, Chew KW, Giganti MJ, Daar ES, Wohl DA, Javan AC, Kantor A, Moser C, Coombs RW, Neytman G, Hoover K, Jana A, Hart PA, Greninger AL, Szurgot B, Eron JJ, Currier JS, Hughes MD, Smith DM, Li JZ
published in: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
information resource reference: One Week of Oral Camostat Versus Placebo in Nonhospitalized Adults With Mild-to-Moderate Coronavirus Disease 2019: A Randomized Controlled Phase 2 Trial. Clin Infect Dis. 2023 10 05; 77(7):941-949.
journal title abbreviation: Clin Infect Dis
publication date: 2023-10-05T00:00:00
year: 2023
type: Academic Article
type: Article
type: Document
type: Information Resource

Statistical Challenges when Analyzing SARS-CoV-2 RNA Measurements Below the Assay Limit of Quantification in COVID-19 Clinical Trials.
PubMed Identifier: 36993419
author list: Moser CB, Chew KW, Giganti MJ, Li JZ, Aga E, Ritz J, Greninger AL, Javan AC, Daar ES, Currier JS, Eron JJ, Smith DM, Hughes MD
published in: medRxiv : the preprint server for health sciences
information resource reference: Statistical Challenges when Analyzing SARS-CoV-2 RNA Measurements Below the Assay Limit of Quantification in COVID-19 Clinical Trials. medRxiv. 2023 Mar 17.
journal title abbreviation: medRxiv
publication date: 2023-03-17T00:00:00
year: 2023
type: Academic Article
type: Article
type: Document
type: Information Resource

Safety and Efficacy of Combined Tixagevimab and Cilgavimab Administered Intramuscularly or Intravenously in Nonhospitalized Patients With COVID-19: 2 Randomized Clinical Trials.
PubMed Identifier: 37099295
author list: Bender Ignacio RA, Chew KW, Moser C, Currier JS, Eron JJ, Javan AC, Giganti MJ, Aga E, Gibbs M, Tchouakam Kouekam H, Johnsson E, Esser MT, Hoover K, Neytman G, Newell M, Daar ES, Fischer W, Fletcher CV, Li JZ, Greninger AL, Coombs RW, Hughes MD, Smith D, Wohl DA
published in: JAMA network open
information resource reference: Safety and Efficacy of Combined Tixagevimab and Cilgavimab Administered Intramuscularly or Intravenously in Nonhospitalized Patients With COVID-19: 2 Randomized Clinical Trials. JAMA Netw Open. 2023 04 03; 6(4):e2310039.
journal title abbreviation: JAMA Netw Open
publication date: 2023-04-03T00:00:00
year: 2023
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1552900
type: Authorship
author rank in publication: 22
linked author: Hughes, Michael
linked information resource: Safety and Efficacy of Combined Tixagevimab and Cilgavimab Administered Intramuscularly or Intravenously in Nonhospitalized Patients With COVID-19: 2 Randomized Clinical Trials.

Authorship 1553143
type: Authorship
author rank in publication: 13
linked author: Hughes, Michael
linked information resource: Statistical Challenges when Analyzing SARS-CoV-2 RNA Measurements Below the Assay Limit of Quantification in COVID-19 Clinical Trials.

Authorship 1565732
type: Authorship
author rank in publication: 25
linked author: Hughes, Michael
linked information resource: Safety and Efficacy of Combination SARS-CoV-2 Neutralizing Monoclonal Antibodies Amubarvimab Plus Romlusevimab in Nonhospitalized Patients With COVID-19.

Authorship 1571305
type: Authorship
author rank in publication: 6
linked author: Hughes, Michael
linked information resource: 1-Year Incidence of Tuberculosis Infection and Disease Among Household Contacts of Rifampin- and Multidrug-Resistant Tuberculosis.

Authorship 1564368
type: Authorship
author rank in publication: 2
linked author: Hughes, Michael
linked information resource: Dietary Iron Intake and HIV-Related Outcomes Among Adults Initiating Antiretroviral Therapy in Tanzania.

Authorship 1569807
type: Authorship
author rank in publication: 18
linked author: Hughes, Michael
linked information resource: One Week of Oral Camostat Versus Placebo in Nonhospitalized Adults With Mild-to-Moderate Coronavirus Disease 2019: A Randomized Controlled Phase 2 Trial.

Dietary Iron Intake and HIV-Related Outcomes Among Adults Initiating Antiretroviral Therapy in Tanzania.
PubMed Identifier: 37199401
author list: Abioye AI, Hughes MD, Sudfeld CR, Noor RA, Isanaka S, Lukmanji Z, Mugusi F, Fawzi WW
published in: Journal of acquired immune deficiency syndromes (1999)
information resource reference: Dietary Iron Intake and HIV-Related Outcomes Among Adults Initiating Antiretroviral Therapy in Tanzania. J Acquir Immune Defic Syndr. 2023 09 01; 94(1):57-65.
journal title abbreviation: J Acquir Immune Defic Syndr
publication date: 2023-09-01T00:00:00
year: 2023
type: Academic Article
type: Article
type: Document
type: Information Resource

1-Year Incidence of Tuberculosis Infection and Disease Among Household Contacts of Rifampin- and Multidrug-Resistant Tuberculosis.
PubMed Identifier: 37227925
author list: Krishnan S, Wu X, Kim S, McIntire K, Naini L, Hughes MD, Dawson R, Mave V, Gaikwad S, Sanchez J, Mendoza-Ticona A, Gonzales P, Comins K, Shenje J, Fontain SN, Omozoarhe A, Mohapi L, Lalloo UG, Garcia Ferreira AC, Mugah C, Harrington M, Shah NS, Hesseling AC, Churchyard G, Swindells S, Gupta A
published in: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
information resource reference: 1-Year Incidence of Tuberculosis Infection and Disease Among Household Contacts of Rifampin- and Multidrug-Resistant Tuberculosis. Clin Infect Dis. 2023 09 18; 77(6):892-900.
journal title abbreviation: Clin Infect Dis
publication date: 2023-09-18T00:00:00
year: 2023
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 293827
type: Authorship
author rank in publication: 3
linked author: Hughes, Michael
linked information resource: https://connects.catalyst.harvard.edu/Profiles/profile/799122

Statistical Challenges When Analyzing SARS-CoV-2 RNA Measurements Below the Assay Limit of Quantification in COVID-19 Clinical Trials.
PubMed Identifier: 37650235
author list: Moser CB, Chew KW, Giganti MJ, Li JZ, Aga E, Ritz J, Greninger AL, Javan AC, Bender Ignacio R, Daar ES, Wohl DA, Currier JS, Eron JJ, Smith DM, Hughes MD
published in: The Journal of infectious diseases
information resource reference: Statistical Challenges When Analyzing SARS-CoV-2 RNA Measurements Below the Assay Limit of Quantification in COVID-19 Clinical Trials. J Infect Dis. 2023 08 31; 228(Suppl 2):S101-S110.
journal title abbreviation: J Infect Dis
publication date: 2023-08-31T00:00:00
year: 2023
type: Academic Article
type: Article
type: Document
type: Information Resource

ACTIV-2: A Platform Trial for the Evaluation of Novel Therapeutics for the Treatment of Early COVID-19 in Outpatients.
PubMed Identifier: 37650231
author list: Currier JS, Moser C, Eron JJ, Chew KW, Smith DM, Javan AC, Wohl DA, Daar ES, Hughes MD
published in: The Journal of infectious diseases
information resource reference: ACTIV-2: A Platform Trial for the Evaluation of Novel Therapeutics for the Treatment of Early COVID-19 in Outpatients. J Infect Dis. 2023 08 31; 228(Suppl 2):S77-S82.
journal title abbreviation: J Infect Dis
publication date: 2023-08-31T00:00:00
year: 2023
type: Academic Article
type: Article
type: Document
type: Information Resource

Long COVID After Bamlanivimab Treatment.
PubMed Identifier: 37650236
author list: Evering TH, Moser CB, Jilg N, Yeh E, Sanusi B, Wohl DA, Daar ES, Li JZ, Klekotka P, Javan AC, Eron JJ, Currier JS, Hughes MD, Smith DM, Chew KW
published in: The Journal of infectious diseases
information resource reference: Long COVID After Bamlanivimab Treatment. J Infect Dis. 2023 08 31; 228(Suppl 2):S126-S135.
journal title abbreviation: J Infect Dis
publication date: 2023-08-31T00:00:00
year: 2023
type: Academic Article
type: Article
type: Document
type: Information Resource

Validity and Characterization of Time to Symptom Resolution Outcome Measures in the ACTIV-2/A5401 Outpatient COVID-19 Treatment Trial.
PubMed Identifier: 37650237
author list: Chew KW, Moser C, Yeh E, Wohl DA, Daar ES, Ritz J, Javan AC, Eron JJ, Currier JS, Smith DM, Hughes MD
published in: The Journal of infectious diseases
information resource reference: Validity and Characterization of Time to Symptom Resolution Outcome Measures in the ACTIV-2/A5401 Outpatient COVID-19 Treatment Trial. J Infect Dis. 2023 08 31; 228(Suppl 2):S83-S91.
journal title abbreviation: J Infect Dis
publication date: 2023-08-31T00:00:00
year: 2023
type: Academic Article
type: Article
type: Document
type: Information Resource

Association Between Anterior Nasal and Plasma SARS-CoV-2 RNA Levels and Hospitalization or Death in Nonhospitalized Adults With Mild-to-Moderate COVID-19.
PubMed Identifier: 37650230
author list: Giganti MJ, Chew KW, Eron JJ, Li JZ, Pinilla M, Moser C, Javan AC, Fischer WA, Klekotka P, Margolis D, Wohl DA, Coombs RW, Daar ES, Smith DM, Currier JS, Hughes MD
published in: The Journal of infectious diseases
information resource reference: Association Between Anterior Nasal and Plasma SARS-CoV-2 RNA Levels and Hospitalization or Death in Nonhospitalized Adults With Mild-to-Moderate COVID-19. J Infect Dis. 2023 08 31; 228(Suppl 2):S117-S125.
journal title abbreviation: J Infect Dis
publication date: 2023-08-31T00:00:00
year: 2023
type: Academic Article
type: Article
type: Document
type: Information Resource

Immune Status and SARS-CoV-2 Viral Dynamics.
PubMed Identifier: 37650232
author list: Li Y, Moser C, Aga E, Currier JS, Wohl DA, Daar ES, Ritz J, Greninger AL, Sieg S, Parikh UM, Coombs RW, Hughes MD, Eron JJ, Smith DM, Chew KW, Li JZ
published in: The Journal of infectious diseases
information resource reference: Immune Status and SARS-CoV-2 Viral Dynamics. J Infect Dis. 2023 08 31; 228(Suppl 2):S111-S116.
journal title abbreviation: J Infect Dis
publication date: 2023-08-31T00:00:00
year: 2023
type: Academic Article
type: Article
type: Document
type: Information Resource

Variant-Specific Viral Kinetics in Acute COVID-19.
PubMed Identifier: 37650233
author list: Ribeiro RM, Choudhary MC, Deo R, Giganti MJ, Moser C, Ritz J, Greninger AL, Regan J, Flynn JP, Wohl DA, Currier JS, Eron JJ, Hughes MD, Smith DM, Chew KW, Daar ES, Perelson AS, Li JZ
published in: The Journal of infectious diseases
information resource reference: Variant-Specific Viral Kinetics in Acute COVID-19. J Infect Dis. 2023 08 31; 228(Suppl 2):S136-S143.
journal title abbreviation: J Infect Dis
publication date: 2023-08-31T00:00:00
year: 2023
type: Academic Article
type: Article
type: Document
type: Information Resource

Pooling Different Placebos as a Control Group in a Randomized Platform Trial: Benefits and Challenges From Experience in the ACTIV-2 COVID-19 Trial.
PubMed Identifier: 37650234
author list: Moser CB, Chew KW, Ritz J, Newell M, Javan AC, Eron JJ, Daar ES, Wohl DA, Currier JS, Smith DM, Hughes MD
published in: The Journal of infectious diseases
information resource reference: Pooling Different Placebos as a Control Group in a Randomized Platform Trial: Benefits and Challenges From Experience in the ACTIV-2 COVID-19 Trial. J Infect Dis. 2023 08 31; 228(Suppl 2):S92-S100.
journal title abbreviation: J Infect Dis
publication date: 2023-08-31T00:00:00
year: 2023
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1590674
type: Authorship
author rank in publication: 11
linked author: Hughes, Michael
linked information resource: Pooling Different Placebos as a Control Group in a Randomized Platform Trial: Benefits and Challenges From Experience in the ACTIV-2 COVID-19 Trial.

Authorship 1590667
type: Authorship
author rank in publication: 9
linked author: Hughes, Michael
linked information resource: ACTIV-2: A Platform Trial for the Evaluation of Novel Therapeutics for the Treatment of Early COVID-19 in Outpatients.

Authorship 1590675
type: Authorship
author rank in publication: 15
linked author: Hughes, Michael
linked information resource: Statistical Challenges When Analyzing SARS-CoV-2 RNA Measurements Below the Assay Limit of Quantification in COVID-19 Clinical Trials.

Authorship 1590681
type: Authorship
author rank in publication: 11
linked author: Hughes, Michael
linked information resource: Validity and Characterization of Time to Symptom Resolution Outcome Measures in the ACTIV-2/A5401 Outpatient COVID-19 Treatment Trial.

Authorship 1590668
type: Authorship
author rank in publication: 12
linked author: Hughes, Michael
linked information resource: Immune Status and SARS-CoV-2 Viral Dynamics.

Authorship 1582729
type: Authorship
author rank in publication: 9
linked author: Hughes, Michael
linked information resource: Modeling the emergence of viral resistance for SARS-CoV-2 during treatment with an anti-spike monoclonal antibody.

Authorship 1590679
type: Authorship
author rank in publication: 13
linked author: Hughes, Michael
linked information resource: Long COVID After Bamlanivimab Treatment.

Authorship 1590670
type: Authorship
author rank in publication: 13
linked author: Hughes, Michael
linked information resource: Variant-Specific Viral Kinetics in Acute COVID-19.

Authorship 1583887
type: Authorship
author rank in publication: 2
linked author: Hughes, Michael
linked information resource: Adverse Pregnancy Outcomes Among Women with Human Immunodeficiency Virus Taking Isoniazid Preventive Therapy During the First Trimester.

Authorship 1590654
type: Authorship
author rank in publication: 16
linked author: Hughes, Michael
linked information resource: Association Between Anterior Nasal and Plasma SARS-CoV-2 RNA Levels and Hospitalization or Death in Nonhospitalized Adults With Mild-to-Moderate COVID-19.

Adverse Pregnancy Outcomes Among Women with Human Immunodeficiency Virus Taking Isoniazid Preventive Therapy During the First Trimester.
PubMed Identifier: 37768207
author list: Gupta A, Hughes MD, Cruz JL, Avihingsanon A, Mwelase N, Severe P, Omoz-Oarhe A, Masheto G, Moran L, Benson CA, Chaisson RE, Swindells S
published in: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
information resource reference: Adverse Pregnancy Outcomes Among Women with Human Immunodeficiency Virus Taking Isoniazid Preventive Therapy During the First Trimester. Clin Infect Dis. 2024 03 20; 78(3):667-673.
journal title abbreviation: Clin Infect Dis
publication date: 2024-03-20T00:00:00
year: 2024
type: Academic Article
type: Article
type: Document
type: Information Resource

Modeling the emergence of viral resistance for SARS-CoV-2 during treatment with an anti-spike monoclonal antibody.
PubMed Identifier: 37745410
author list: Phan T, Zitzmann C, Chew KW, Smith DM, Daar ES, Wohl DA, Eron JJ, Currier JS, Hughes MD, Choudhary MC, Deo R, Li JZ, Ribeiro RM, Ke R, Perelson AS
published in: bioRxiv : the preprint server for biology
information resource reference: Modeling the emergence of viral resistance for SARS-CoV-2 during treatment with an anti-spike monoclonal antibody. bioRxiv. 2023 Sep 17.
journal title abbreviation: bioRxiv
publication date: 2023-09-17T00:00:00
year: 2023
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1597107
type: Authorship
author rank in publication: 2
linked author: Hughes, Michael
linked information resource: Incidence and Predictors of Pregnancy in Women Enrolled in Large Multinational HIV Treatment Trials of the AIDS Clinical Trials Group.

Incidence and Predictors of Pregnancy in Women Enrolled in Large Multinational HIV Treatment Trials of the AIDS Clinical Trials Group.
PubMed Identifier: 37820116
author list: Omoz-Oarhe AE, Hughes MD, Yajing B, Short WR, Mngqibisa R, Cohn SE, Weinberg A, La Rosa A, Collier A, Samaneka W, Morroni C, Lockman S
published in: Journal of acquired immune deficiency syndromes (1999)
information resource reference: Incidence and Predictors of Pregnancy in Women Enrolled in Large Multinational HIV Treatment Trials of the AIDS Clinical Trials Group. J Acquir Immune Defic Syndr. 2023 12 15; 94(5):461-467.
journal title abbreviation: J Acquir Immune Defic Syndr
publication date: 2023-12-15T00:00:00
year: 2023
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 398870
type: Authorship
author rank in publication: 2
linked author: Hughes, Michael
linked information resource: Psychiatric hospitalizations among children and youths with human immunodeficiency virus infection.

Authorship 413042
type: Authorship
author rank in publication: 6
linked author: Hughes, Michael
linked information resource: Early archiving and predominance of nonnucleoside reverse transcriptase inhibitor-resistant HIV-1 among recently infected infants born in the United States.

Authorship 446116
type: Authorship
author rank in publication: 2
linked author: Hughes, Michael
linked information resource: Impact of MCP-1-2518-G allele on the HIV-1 disease of children in the United States.

Authorship 1601361
type: Authorship
author rank in publication: 4
linked author: Hughes, Michael
linked information resource: Safety and efficacy of inhaled interferon-ß1a (SNG001) in adults with mild-to-moderate COVID-19: a randomized, controlled, phase II trial.

Safety and efficacy of inhaled interferon-ß1a (SNG001) in adults with mild-to-moderate COVID-19: a randomized, controlled, phase II trial.
PubMed Identifier: 37855026
author list: Jagannathan P, Chew KW, Giganti MJ, Hughes MD, Moser C, Main MJ, Monk PD, Javan AC, Li JZ, Fletcher CV, McCarthy C, Wohl DA, Daar ES, Eron JJ, Currier JS, Singh U, Smith DM, Fischer W
published in: EClinicalMedicine
information resource reference: Safety and efficacy of inhaled interferon-ß1a (SNG001) in adults with mild-to-moderate COVID-19: a randomized, controlled, phase II trial. EClinicalMedicine. 2023 Nov; 65:102250.
journal title abbreviation: EClinicalMedicine
publication date: 2023-10-06T00:00:00
year: 2023
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 457701
type: Authorship
author rank in publication: 2
linked author: Hughes, Michael
linked information resource: https://connects.catalyst.harvard.edu/Profiles/profile/763589

Authorship 1608979
type: Authorship
author rank in publication: 16
linked author: Hughes, Michael
linked information resource: SARS-CoV-2 monoclonal antibody treatment followed by vaccination shifts human memory B cell epitope recognition suggesting antibody feedback.

Authorship 1610038
type: Authorship
author rank in publication: 18
linked author: Hughes, Michael
linked information resource: Early antiviral CD4 and CD8 T cell responses and antibodies are associated with upper respiratory tract clearance of SARS-CoV-2.

Early antiviral CD4 and CD8 T cell responses and antibodies are associated with upper respiratory tract clearance of SARS-CoV-2.
PubMed Identifier: 37961119
author list: Ramirez SI, Lopez PG, Faraji F, Parikh UM, Heaps A, Ritz J, Moser C, Eron JJ, Wohl DA, Currier JS, Daar ES, Greninger AL, Klekotka P, Grifoni A, Weiskopf D, Sette A, Peters B, Hughes MD, Chew KW, Smith DM, Crotty S
published in: bioRxiv : the preprint server for biology
information resource reference: Early antiviral CD4 and CD8 T cell responses and antibodies are associated with upper respiratory tract clearance of SARS-CoV-2. bioRxiv. 2024 Aug 19.
journal title abbreviation: bioRxiv
publication date: 2024-08-19T00:00:00
year: 2024
type: Academic Article
type: Article
type: Document
type: Information Resource

SARS-CoV-2 monoclonal antibody treatment followed by vaccination shifts human memory B cell epitope recognition suggesting antibody feedback.
PubMed Identifier: 38045374
author list: Coelho CH, Bloom N, Ramirez SI, Parikh UM, Heaps A, Sieg SF, Greninger A, Ritz J, Moser C, Eron JJ, Currier JS, Klekotka P, Wohl DA, Daar ES, Li J, Hughes MD, Chew KW, Smith DM, Crotty S
published in: bioRxiv : the preprint server for biology
information resource reference: SARS-CoV-2 monoclonal antibody treatment followed by vaccination shifts human memory B cell epitope recognition suggesting antibody feedback. bioRxiv. 2023 Nov 22.
journal title abbreviation: bioRxiv
publication date: 2023-11-22T00:00:00
year: 2023
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 494508
type: Authorship
author rank in publication: 2
linked author: Hughes, Michael
linked information resource: Treatment-mediated changes in human immunodeficiency virus (HIV) type 1 RNA and CD4 cell counts as predictors of weight growth failure, cognitive decline, and survival in HIV-infected children.

Authorship 496990
type: Authorship
author rank in publication: 3
linked author: Hughes, Michael
linked information resource: A prospective, randomized trial of clear liquids versus low-fat solid diet as the initial meal in mild acute pancreatitis.

Authorship 508196
type: Authorship
author rank in publication: 3
linked author: Hughes, Michael
linked information resource: Osteonecrosis of the hip (Legg-Calvé-Perthes disease) in human immunodeficiency virus-infected children.

Authorship 1618642
type: Authorship
author rank in publication: 3
linked author: Hughes, Michael
linked information resource: Discontinuation of tenofovir disoproxil fumarate from initial ART regimens because of renal adverse events: An analysis of data from four multi-country clinical trials.

Discontinuation of tenofovir disoproxil fumarate from initial ART regimens because of renal adverse events: An analysis of data from four multi-country clinical trials.
PubMed Identifier: 38175824
author list: Ngongondo M, Ritz J, Hughes MD, Matoga M, Hosseinipour MC
published in: PLOS global public health
information resource reference: Discontinuation of tenofovir disoproxil fumarate from initial ART regimens because of renal adverse events: An analysis of data from four multi-country clinical trials. PLOS Glob Public Health. 2024; 4(1):e0002648.
journal title abbreviation: PLOS Glob Public Health
publication date: 2024-01-04T00:00:00
year: 2024
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 575636
type: Authorship
author rank in publication: 1
linked author: Hughes, Michael
linked information resource: Evaluating surrogate endpoints.

Authorship 1627833
type: Authorship
author rank in publication: 6
linked author: Hughes, Michael
linked information resource: Response to Drs de Grooth and Parienti.

Response to Drs de Grooth and Parienti.
PubMed Identifier: 38324658
author list: Giganti MJ, Chew KW, Eron JJ, Smith DM, Currier JS, Hughes MD
published in: The Journal of infectious diseases
information resource reference: Response to Drs de Grooth and Parienti. J Infect Dis. 2024 May 15; 229(5):1596.
journal title abbreviation: J Infect Dis
publication date: 2024-05-15T00:00:00
year: 2024
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 524047
type: Authorship
author rank in publication: 6
linked author: Hughes, Michael
linked information resource: CT-guided aspiration of suspected pancreatic infection: bacteriology and clinical outcome.

Authorship 155164
type: Authorship
author rank in publication: 5
linked author: Hughes, Michael
linked information resource: Early initiation of lopinavir/ritonavir in infants less than 6 weeks of age: pharmacokinetics and 24-week safety and efficacy.

Authorship 1654156
type: Authorship
author rank in publication: 3
linked author: Hughes, Michael
linked information resource: Oral Simnotrelvir for Adult Patients with Mild-to-Moderate Covid-19.

Authorship 1646808
type: Authorship
author rank in publication: 19
linked author: Hughes, Michael
linked information resource: Characterization of Treatment Resistance and Viral Kinetics in the Setting of Single-Active Versus Dual-Active Monoclonal Antibodies Against Severe Acute Respiratory Syndrome Coronavirus 2.

Modeling the emergence of viral resistance for SARS-CoV-2 during treatment with an anti-spike monoclonal antibody.
PubMed Identifier: 38635853
author list: Phan T, Zitzmann C, Chew KW, Smith DM, Daar ES, Wohl DA, Eron JJ, Currier JS, Hughes MD, Choudhary MC, Deo R, Li JZ, Ribeiro RM, Ke R, Perelson AS
published in: PLoS pathogens
information resource reference: Modeling the emergence of viral resistance for SARS-CoV-2 during treatment with an anti-spike monoclonal antibody. PLoS Pathog. 2024 Apr; 20(4):e1011680.
journal title abbreviation: PLoS Pathog
publication date: 2024-04-18T00:00:00
year: 2024
type: Academic Article
type: Article
type: Document
type: Information Resource

Oral Simnotrelvir for Adult Patients with Mild-to-Moderate Covid-19.
PubMed Identifier: 38657253
author list: Moser CB, Li JZ, Hughes MD
published in: The New England journal of medicine
information resource reference: Oral Simnotrelvir for Adult Patients with Mild-to-Moderate Covid-19. N Engl J Med. 2024 04 25; 390(16):1533-1534.
journal title abbreviation: N Engl J Med
publication date: 2024-04-25T00:00:00
year: 2024
type: Academic Article
type: Article
type: Document
type: Information Resource

Characterization of Treatment Resistance and Viral Kinetics in the Setting of Single-Active Versus Dual-Active Monoclonal Antibodies Against Severe Acute Respiratory Syndrome Coronavirus 2.
PubMed Identifier: 38716969
author list: Choudhary MC, Deo R, Evering TH, Chew KW, Giganti MJ, Moser C, Ritz J, Regan J, Flynn JP, Crain CR, Wohl DA, Currier JS, Eron JJ, Margolis D, Zhu Q, Zhon L, Ya L, Greninger AL, Hughes MD, Smith D, Daar ES, Li JZ
published in: The Journal of infectious diseases
information resource reference: Characterization of Treatment Resistance and Viral Kinetics in the Setting of Single-Active Versus Dual-Active Monoclonal Antibodies Against Severe Acute Respiratory Syndrome Coronavirus 2. J Infect Dis. 2024 Aug 16; 230(2):394-402.
journal title abbreviation: J Infect Dis
publication date: 2024-08-16T00:00:00
year: 2024
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 374996
type: Authorship
author rank in publication: 2
linked author: Hughes, Michael
linked information resource: Statistical problems in the reporting of clinical trials. A survey of three medical journals.

Authorship 1667602
type: Authorship
author rank in publication: 11
linked author: Hughes, Michael
linked information resource: SARS-CoV-2 Plasma Antibody and Nucleocapsid Antigen Status Predict Outcomes in Outpatients With COVID-19.

SARS-CoV-2 Plasma Antibody and Nucleocapsid Antigen Status Predict Outcomes in Outpatients With COVID-19.
PubMed Identifier: 39018444
author list: Jilg N, Giganti MJ, Chew KW, Shaw-Saliba K, Ritz J, Moser C, Evering TH, Daar ES, Eron JJ, Currier JS, Hughes MD, Lane HC, Dewar R, Smith DM, Li JZ
published in: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
information resource reference: SARS-CoV-2 Plasma Antibody and Nucleocapsid Antigen Status Predict Outcomes in Outpatients With COVID-19. Clin Infect Dis. 2024 10 15; 79(4):920-927.
journal title abbreviation: Clin Infect Dis
publication date: 2024-10-15T00:00:00
year: 2024
type: Academic Article
type: Article
type: Document
type: Information Resource

Safety and Efficacy of SAB-185 for Nonhospitalized Adults With COVID-19: A Randomized Clinical Trial.
PubMed Identifier: 39028902
author list: Chew KW, Taiwo BO, Moser C, Daar ES, Wohl DA, Ritz J, Javan AC, Li JZ, Fischer W, Greninger AL, Bausch C, Luke T, Call R, Neytman G, Giganti MJ, Fletcher CV, Hughes MD, Eron JJ, Currier JS, Smith DM
published in: The Journal of infectious diseases
information resource reference: Safety and Efficacy of SAB-185 for Nonhospitalized Adults With COVID-19: A Randomized Clinical Trial. J Infect Dis. 2024 Nov 15; 230(5):1177-1186.
journal title abbreviation: J Infect Dis
publication date: 2024-11-15T00:00:00
year: 2024
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 418107
type: Authorship
author rank in publication: 3
linked author: Hughes, Michael
linked information resource: A trial comparing nucleoside monotherapy with combination therapy in HIV-infected adults with CD4 cell counts from 200 to 500 per cubic millimeter. AIDS Clinical Trials Group Study 175 Study Team.

Associate Professor of Medicine
is primary position: true
position in department: Medicine
position in division: Infectious Disease
sort order: 1
type: Position
HR job title: Associate Professor of Medicine
position in organization: Brigham and Women's Hospital

Authorship 447596
type: Authorship
author rank in publication: 2
linked author: Hughes, Michael
linked information resource: Long term tolerability and safety of enfuvirtide for human immunodeficiency virus 1-infected children.

Authorship 248683
type: Authorship
author rank in publication: 1
linked author: Hughes, Michael
linked information resource: Power considerations for clinical trials using multivariate time-to-event data.

Authorship 640616
type: Authorship
author rank in publication: 3
linked author: Hughes, Michael
linked information resource: Associations of proinflammatory cytokine levels with lipid profiles, growth, and body composition in HIV-infected children initiating or changing antiretroviral therapy.

Authorship 640710
type: Authorship
author rank in publication: 3
linked author: Hughes, Michael
linked information resource: Failure of initial therapy with two nucleosides and efavirenz is not associated with early emergence of mutations in the C-terminus of HIV-1 reverse transcriptase.

Authorship 632828
type: Authorship
author rank in publication: 1
linked author: Hughes, Michael
linked information resource: Within-subject diastolic blood pressure variability: implications for risk assessment and screening.

Authorship 636240
type: Authorship
author rank in publication: 3
linked author: Hughes, Michael
linked information resource: Randomized, double-blind, placebo-controlled trial of somatostatin for variceal bleeding. Emergency control and prevention of early variceal rebleeding.

Authorship 655292
type: Authorship
author rank in publication: 4
linked author: Hughes, Michael
linked information resource: Increased risk of preterm delivery among HIV-infected women randomized to protease versus nucleoside reverse transcriptase inhibitor-based HAART during pregnancy.

Authorship 641126
type: Authorship
author rank in publication: 13
linked author: Hughes, Michael
linked information resource: Greater suppression of nevirapine resistance with 21- vs 7-day antiretroviral regimens after intrapartum single-dose nevirapine for prevention of mother-to-child transmission of HIV.

Authorship 656785
type: Authorship
author rank in publication: 12
linked author: Hughes, Michael
linked information resource: Role of low-frequency HIV-1 variants in failure of nevirapine-containing antiviral therapy in women previously exposed to single-dose nevirapine.

Authorship 665954
type: Authorship
author rank in publication: 6
linked author: Hughes, Michael
linked information resource: The design of single-arm clinical trials of combination antiretroviral regimens for treatment-naive HIV-infected patients.

Authorship 660066
type: Authorship
author rank in publication: 2
linked author: Hughes, Michael
linked information resource: Factors affecting timing of antiretroviral treatment initiation based on monitoring CD4 counts.

Authorship 648122
type: Authorship
author rank in publication: 3
linked author: Hughes, Michael
linked information resource: Highly active antiretroviral therapy versus zidovudine for prevention of mother-to-child transmission in a programmatic setting, Botswana.

Authorship 662781
type: Authorship
author rank in publication: 3
linked author: Hughes, Michael
linked information resource: Nevirapine pharmacokinetics and risk of rash and hepatitis among HIV-infected sub-Saharan African women.

Authorship 639430
type: Authorship
author rank in publication: 10
linked author: Hughes, Michael
linked information resource: https://connects.catalyst.harvard.edu/Profiles/profile/25889019

Authorship 641675
type: Authorship
author rank in publication: 2
linked author: Hughes, Michael
linked information resource: Genotype assays and third-line ART in resource-limited settings: a simulation and cost-effectiveness analysis of a planned clinical trial.

Authorship 641148
type: Authorship
author rank in publication: 2
linked author: Hughes, Michael
linked information resource: https://connects.catalyst.harvard.edu/Profiles/profile/25895049

Authorship 653296
type: Authorship
author rank in publication: 3
linked author: Hughes, Michael
linked information resource: The impact of psoriasis on pregnancy outcomes.

Authorship 635512
type: Authorship
author rank in publication: 1
linked author: Hughes, Michael
linked information resource: Fetal omphalocele: prenatal US detection of concurrent anomalies and other predictors of outcome.

Authorship 645494
type: Authorship
author rank in publication: 3
linked author: Hughes, Michael
linked information resource: An internationally generalizable risk index for mortality after one year of antiretroviral therapy.

Authorship 643888
type: Authorship
author rank in publication: 6
linked author: Hughes, Michael
linked information resource: Vitamin D deficiency and anthropometric indicators of adiposity in school-age children: a prospective study.

Authorship 652247
type: Authorship
author rank in publication: 2
linked author: Hughes, Michael
linked information resource: Antiretroviral therapies in women after single-dose nevirapine exposure.

Authorship 662147
type: Authorship
author rank in publication: 4
linked author: Hughes, Michael
linked information resource: Changes in HIV-1 subtypes B and C genital tract RNA in women and men after initiation of antiretroviral therapy.

Authorship 640804
type: Authorship
author rank in publication: 4
linked author: Hughes, Michael
linked information resource: First-line antiretroviral therapy after single-dose nevirapine exposure in South Africa: a cost-effectiveness analysis of the OCTANE trial.

Authorship 653677
type: Authorship
author rank in publication: 4
linked author: Hughes, Michael
linked information resource: Dynamics of the resting CD4(+) T-cell latent HIV reservoir in infants initiating HAART less than 6 months of age.

Authorship 655580
type: Authorship
author rank in publication: 3
linked author: Hughes, Michael
linked information resource: Predictors of growth and body composition in HIV-infected children beginning or changing antiretroviral therapy.

Authorship 642329
type: Authorship
author rank in publication: 3
linked author: Hughes, Michael
linked information resource: Differential associations of leptin with adiposity across early childhood.

Authorship 647422
type: Authorship
author rank in publication: 2
linked author: Hughes, Michael
linked information resource: Nevirapine- versus lopinavir/ritonavir-based initial therapy for HIV-1 infection among women in Africa: a randomized trial.

Authorship 663168
type: Authorship
author rank in publication: 3
linked author: Hughes, Michael
linked information resource: High viral load and elevated angiogenic markers associated with increased risk of preeclampsia among women initiating highly active antiretroviral therapy in pregnancy in the Mma Bana study, Botswana.

Authorship 662366
type: Authorship
author rank in publication: 3
linked author: Hughes, Michael
linked information resource: Choline intake during pregnancy and child cognition at age 7 years.

Authorship 650927
type: Authorship
author rank in publication: 3
linked author: Hughes, Michael
linked information resource: Nevirapine versus ritonavir-boosted lopinavir for HIV-infected children.

Authorship 663974
type: Authorship
author rank in publication: 3
linked author: Hughes, Michael
linked information resource: Increased risk of severe infant anemia after exposure to maternal HAART, Botswana.

Authorship 652721
type: Authorship
author rank in publication: 3
linked author: Hughes, Michael
linked information resource: Antiretroviral treatment for children with peripartum nevirapine exposure.

Authorship 655634
type: Authorship
author rank in publication: 4
linked author: Hughes, Michael
linked information resource: Long-term outcomes for HIV-infected infants less than 6 months of age at initiation of lopinavir/ritonavir combination antiretroviral therapy.

Authorship 655448
type: Authorship
author rank in publication: 5
linked author: Hughes, Michael
linked information resource: HIV-1 protease inhibitors and clinical malaria: a secondary analysis of the AIDS Clinical Trials Group A5208 study.

Authorship 642512
type: Authorship
author rank in publication: 7
linked author: Hughes, Michael
linked information resource: Three-year safety and efficacy of vicriviroc, a CCR5 antagonist, in HIV-1-infected treatment-experienced patients.

Authorship 659967
type: Authorship
author rank in publication: 4
linked author: Hughes, Michael
linked information resource: Stability of autistic traits in the general population: further evidence for a continuum of impairment.

Fetal omphalocele: prenatal US detection of concurrent anomalies and other predictors of outcome.
PubMed Identifier: 2678251
author list: Hughes MD, Nyberg DA, Mack LA, Pretorius DH
published in: Radiology
information resource reference: Fetal omphalocele: prenatal US detection of concurrent anomalies and other predictors of outcome. Radiology. 1989 Nov; 173(2):371-6.
journal title abbreviation: Radiology
publication date: 1989-11-01T00:00:00
year: 1989
type: Academic Article
type: Article
type: Document
type: Information Resource

Randomized, double-blind, placebo-controlled trial of somatostatin for variceal bleeding. Emergency control and prevention of early variceal rebleeding.
PubMed Identifier: 1976563
author list: Burroughs AK, McCormick PA, Hughes MD, Sprengers D, D'Heygere F, McIntyre N
published in: Gastroenterology
information resource reference: Randomized, double-blind, placebo-controlled trial of somatostatin for variceal bleeding. Emergency control and prevention of early variceal rebleeding. Gastroenterology. 1990 Nov; 99(5):1388-95.
journal title abbreviation: Gastroenterology
publication date: 1990-11-01T00:00:00
year: 1990
type: Academic Article
type: Article
type: Document
type: Information Resource

Within-subject diastolic blood pressure variability: implications for risk assessment and screening.
PubMed Identifier: 1432027
author list: Hughes MD, Pocock SJ
published in: Journal of clinical epidemiology
information resource reference: Within-subject diastolic blood pressure variability: implications for risk assessment and screening. J Clin Epidemiol. 1992 Sep; 45(9):985-98.
journal title abbreviation: J Clin Epidemiol
publication date: 1992-09-01T00:00:00
year: 1992
type: Academic Article
type: Article
type: Document
type: Information Resource

https://connects.catalyst.harvard.edu/Profiles/profile/25889019
PubMed Identifier: 21288774
author list: Babiker A, Castro nee Green H, Compagnucci A, Fiscus S, Giaquinto C, Gibb DM, Harper L, Harrison L, Hughes M, McKinney R, Melvin A, Mofenson L, Saidi Y, Smith ME, Tudor-Williams G, Walker AS
published in: The Lancet. Infectious diseases
information resource reference: First-line antiretroviral therapy with a protease inhibitor versus non-nucleoside reverse transcriptase inhibitor and switch at higher versus low viral load in HIV-infected children: an open-label, randomised phase 2/3 trial. Lancet Infect Dis. 2011 Apr; 11(4):273-83.
journal title abbreviation: Lancet Infect Dis
publication date: 2011-01-31T00:00:00
year: 2011
type: Academic Article
type: Article
type: Document
type: Information Resource
label: First-line antiretroviral therapy with a protease inhibitor versus non-nucleoside reverse transcriptase inhibitor and switch at higher versus low viral load in HIV-infected children: an open-label, randomised phase 2/3 trial.

Failure of initial therapy with two nucleosides and efavirenz is not associated with early emergence of mutations in the C-terminus of HIV-1 reverse transcriptase.
PubMed Identifier: 21350368
author list: Brehm JH, Lalama CM, Hughes MD, Haubrich R, Riddler SA, Sluis-Cremer N, Mellors JW
published in: Journal of acquired immune deficiency syndromes (1999)
information resource reference: Failure of initial therapy with two nucleosides and efavirenz is not associated with early emergence of mutations in the C-terminus of HIV-1 reverse transcriptase. J Acquir Immune Defic Syndr. 2011 Apr; 56(4):344-8.
journal title abbreviation: J Acquir Immune Defic Syndr
publication date: 2011-04-01T00:00:00
year: 2011
type: Academic Article
type: Article
type: Document
type: Information Resource

Associations of proinflammatory cytokine levels with lipid profiles, growth, and body composition in HIV-infected children initiating or changing antiretroviral therapy.
PubMed Identifier: 20631646
author list: Cervia JS, Chantry CJ, Hughes MD, Alvero C, Meyer WA, Hodge J, Borum P, Moye J, Spector SA
published in: The Pediatric infectious disease journal
information resource reference: Associations of proinflammatory cytokine levels with lipid profiles, growth, and body composition in HIV-infected children initiating or changing antiretroviral therapy. Pediatr Infect Dis J. 2010 Dec; 29(12):1118-22.
journal title abbreviation: Pediatr Infect Dis J
publication date: 2010-12-01T00:00:00
year: 2010
type: Academic Article
type: Article
type: Document
type: Information Resource

Changes in HIV-1 subtypes B and C genital tract RNA in women and men after initiation of antiretroviral therapy.
PubMed Identifier: 23532477
author list: Fiscus SA, Cu-Uvin S, Eshete AT, Hughes MD, Bao Y, Hosseinipour M, Grinsztejn B, Badal-Faesen S, Dragavon J, Coombs RW, Braun K, Moran L, Hakim J, Flanigan T, Kumarasamy N, Campbell TB
published in: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
information resource reference: Changes in HIV-1 subtypes B and C genital tract RNA in women and men after initiation of antiretroviral therapy. Clin Infect Dis. 2013 Jul; 57(2):290-7.
journal title abbreviation: Clin Infect Dis
publication date: 2013-03-26T00:00:00
year: 2013
type: Academic Article
type: Article
type: Document
type: Information Resource

https://connects.catalyst.harvard.edu/Profiles/profile/25895049
PubMed Identifier: 20680986
author list: Noubary F, Hughes MD
published in: Statistics in medicine
information resource reference: Assessing agreement in the timing of treatment initiation determined by repeated measurements of novel versus gold standard technologies with application to the monitoring of CD4 counts in HIV-infected patients. Stat Med. 2010 Aug 15; 29(18):1932-46.
journal title abbreviation: Stat Med
publication date: 2010-08-15T00:00:00
year: 2010
type: Academic Article
type: Article
type: Document
type: Information Resource
label: Assessing agreement in the timing of treatment initiation determined by repeated measurements of novel versus gold standard technologies with application to the monitoring of CD4 counts in HIV-infected patients.

Antiretroviral treatment for children with peripartum nevirapine exposure.
PubMed Identifier: 20942667
author list: Palumbo P, Lindsey JC, Hughes MD, Cotton MF, Bobat R, Meyers T, Bwakura-Dangarembizi M, Chi BH, Musoke P, Kamthunzi P, Schimana W, Purdue L, Eshleman SH, Abrams EJ, Millar L, Petzold E, Mofenson LM, Jean-Philippe P, Violari A
published in: The New England journal of medicine
information resource reference: Antiretroviral treatment for children with peripartum nevirapine exposure. N Engl J Med. 2010 Oct 14; 363(16):1510-20.
journal title abbreviation: N Engl J Med
publication date: 2010-10-14T00:00:00
year: 2010
type: Academic Article
type: Article
type: Document
type: Information Resource

Factors affecting timing of antiretroviral treatment initiation based on monitoring CD4 counts.
PubMed Identifier: 22878419
author list: Noubary F, Hughes MD
published in: Journal of acquired immune deficiency syndromes (1999)
information resource reference: Factors affecting timing of antiretroviral treatment initiation based on monitoring CD4 counts. J Acquir Immune Defic Syndr. 2012 Nov 01; 61(3):326-33.
journal title abbreviation: J Acquir Immune Defic Syndr
publication date: 2012-11-01T00:00:00
year: 2012
type: Academic Article
type: Article
type: Document
type: Information Resource

Dynamics of the resting CD4(+) T-cell latent HIV reservoir in infants initiating HAART less than 6 months of age.
PubMed Identifier: 22555165
author list: Persaud D, Palumbo PE, Ziemniak C, Hughes MD, Alvero CG, Luzuriaga K, Yogev R, Capparelli EV, Chadwick EG
published in: AIDS (London, England)
information resource reference: Dynamics of the resting CD4(+) T-cell latent HIV reservoir in infants initiating HAART less than 6 months of age. AIDS. 2012 Jul 31; 26(12):1483-90.
journal title abbreviation: AIDS
publication date: 2012-07-31T00:00:00
year: 2012
type: Academic Article
type: Article
type: Document
type: Information Resource

Predictors of growth and body composition in HIV-infected children beginning or changing antiretroviral therapy.
PubMed Identifier: 20345880
author list: Chantry CJ, Cervia JS, Hughes MD, Alvero C, Hodge J, Borum P, Moye J
published in: HIV medicine
information resource reference: Predictors of growth and body composition in HIV-infected children beginning or changing antiretroviral therapy. HIV Med. 2010 Oct 01; 11(9):573-83.
journal title abbreviation: HIV Med
publication date: 2010-03-21T00:00:00
year: 2010
type: Academic Article
type: Article
type: Document
type: Information Resource

Nevirapine versus ritonavir-boosted lopinavir for HIV-infected children.
PubMed Identifier: 22716976
author list: Violari A, Lindsey JC, Hughes MD, Mujuru HA, Barlow-Mosha L, Kamthunzi P, Chi BH, Cotton MF, Moultrie H, Khadse S, Schimana W, Bobat R, Purdue L, Eshleman SH, Abrams EJ, Millar L, Petzold E, Mofenson LM, Jean-Philippe P, Palumbo P
published in: The New England journal of medicine
information resource reference: Nevirapine versus ritonavir-boosted lopinavir for HIV-infected children. N Engl J Med. 2012 Jun 21; 366(25):2380-9.
journal title abbreviation: N Engl J Med
publication date: 2012-06-21T00:00:00
year: 2012
type: Academic Article
type: Article
type: Document
type: Information Resource

Long-term outcomes for HIV-infected infants less than 6 months of age at initiation of lopinavir/ritonavir combination antiretroviral therapy.
PubMed Identifier: 21297419
author list: Chadwick EG, Yogev R, Alvero CG, Hughes MD, Hazra R, Pinto JA, Robbins BL, Heckman BE, Palumbo PE, Capparelli EV
published in: AIDS (London, England)
information resource reference: Long-term outcomes for HIV-infected infants less than 6 months of age at initiation of lopinavir/ritonavir combination antiretroviral therapy. AIDS. 2011 Mar 13; 25(5):643-9.
journal title abbreviation: AIDS
publication date: 2011-03-13T00:00:00
year: 2011
type: Academic Article
type: Article
type: Document
type: Information Resource

An internationally generalizable risk index for mortality after one year of antiretroviral therapy.
PubMed Identifier: 23095314
author list: Tate JP, Justice AC, Hughes MD, Bonnet F, Reiss P, Mocroft A, Nattermann J, Lampe FC, Bucher HC, Sterling TR, Crane HM, Kitahata MM, May M, Sterne JA
published in: AIDS (London, England)
information resource reference: An internationally generalizable risk index for mortality after one year of antiretroviral therapy. AIDS. 2013 Feb 20; 27(4):563-72.
journal title abbreviation: AIDS
publication date: 2013-02-20T00:00:00
year: 2013
type: Academic Article
type: Article
type: Document
type: Information Resource

Choline intake during pregnancy and child cognition at age 7 years.
PubMed Identifier: 23425631
author list: Boeke CE, Gillman MW, Hughes MD, Rifas-Shiman SL, Villamor E, Oken E
published in: American journal of epidemiology
information resource reference: Choline intake during pregnancy and child cognition at age 7 years. Am J Epidemiol. 2013 Jun 15; 177(12):1338-47.
journal title abbreviation: Am J Epidemiol
publication date: 2013-02-20T00:00:00
year: 2013
type: Academic Article
type: Article
type: Document
type: Information Resource

Greater suppression of nevirapine resistance with 21- vs 7-day antiretroviral regimens after intrapartum single-dose nevirapine for prevention of mother-to-child transmission of HIV.
PubMed Identifier: 23300238
author list: McMahon DK, Zheng L, Hitti J, Chan ES, Halvas EK, Hong F, Kabanda J, Taulo F, Kumarasamy N, Bonhomme J, Wallis CL, Klingman KL, Hughes MD, Mellors JW
published in: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
information resource reference: Greater suppression of nevirapine resistance with 21- vs 7-day antiretroviral regimens after intrapartum single-dose nevirapine for prevention of mother-to-child transmission of HIV. Clin Infect Dis. 2013 Apr; 56(7):1044-51.
journal title abbreviation: Clin Infect Dis
publication date: 2013-01-08T00:00:00
year: 2013
type: Academic Article
type: Article
type: Document
type: Information Resource

The statistical design and analysis of pandemic platform trials: Implications for the future.
PubMed Identifier: 39540110
author list: Lindsell CJ, Shotwell M, Anstrom KJ, Berry S, Brittain E, Harrell FE, Geller N, Grund B, Hughes MD, Jagannathan P, Leifer E, Moser CB, Price KL, Proschan M, Stewart T, Thomas S, Touloumi G, LaVange L
published in: Journal of clinical and translational science
information resource reference: The statistical design and analysis of pandemic platform trials: Implications for the future. J Clin Transl Sci. 2024; 8(1):e155.
journal title abbreviation: J Clin Transl Sci
publication date: 2024-10-15T00:00:00
year: 2024
type: Academic Article
type: Article
type: Document
type: Information Resource

Erratum: The statistical design and analysis of pandemic platform trials: Implications for the future - CORRIGENDUM.
PubMed Identifier: 39619071
author list: Lindsell CJ, Shotwell M, Anstrom KJ, Berry S, Brittain E, Harrell FE, Geller N, Grund B, Hughes MD, Jagannathan P, Leifer E, Moser CB, Price KL, Proschan M, Stewart T, Thomas S, Touloumi G, LaVange L
published in: Journal of clinical and translational science
information resource reference: Erratum: The statistical design and analysis of pandemic platform trials: Implications for the future - CORRIGENDUM. J Clin Transl Sci. 2024; 8(1):e177.
journal title abbreviation: J Clin Transl Sci
publication date: 2024-10-28T00:00:00
year: 2024
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 197358
type: Authorship
author rank in publication: 5
linked author: Hughes, Michael
linked information resource: Is severity of necrotizing pancreatitis increased in extended necrosis and infected necrosis?

Authorship 680658
type: Authorship
author rank in publication: 3
linked author: Hughes, Michael
linked information resource: Cotrimoxazole prophylaxis and risk of severe anemia or severe neutropenia in HAART-exposed, HIV-uninfected infants.

Cotrimoxazole prophylaxis and risk of severe anemia or severe neutropenia in HAART-exposed, HIV-uninfected infants.
PubMed Identifier: 24086319
author list: Dryden-Peterson S, Jayeoba O, Hughes MD, Jibril H, McIntosh K, Modise TA, Asmelash A, Powis KM, Essex M, Shapiro RL, Lockman S
published in: PloS one
information resource reference: Cotrimoxazole prophylaxis and risk of severe anemia or severe neutropenia in HAART-exposed, HIV-uninfected infants. PLoS One. 2013; 8(9):e74171.
journal title abbreviation: PLoS One
publication date: 2013-09-23T00:00:00
year: 2013
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 687546
type: Authorship
author rank in publication: 4
linked author: Hughes, Michael
linked information resource: HIV transmission and 24-month survival in a randomized trial of HAART to prevent MTCT during pregnancy and breastfeeding in Botswana.

HIV transmission and 24-month survival in a randomized trial of HAART to prevent MTCT during pregnancy and breastfeeding in Botswana.
PubMed Identifier: 24180000
author list: Shapiro RL, Kitch D, Ogwu A, Hughes MD, Lockman S, Powis K, Souda S, Moffat C, Moyo S, McIntosh K, van Widenfelt E, Zwerski S, Mazhani L, Makhema J, Essex M
published in: AIDS (London, England)
information resource reference: HIV transmission and 24-month survival in a randomized trial of HAART to prevent MTCT during pregnancy and breastfeeding in Botswana. AIDS. 2013 Jul 31; 27(12):1911-20.
journal title abbreviation: AIDS
publication date: 2013-07-31T00:00:00
year: 2013
type: Academic Article
type: Article
type: Document
type: Information Resource

Ensitrelvir for the Treatment of Nonhospitalized Adults with COVID-19: Results from the SCORPIO-HR, Phase 3, Randomized, Double-blind, Placebo-Controlled Trial.
PubMed Identifier: 39960062
author list: Luetkemeyer AF, Chew KW, Lacey S, Hughes MD, Harrison LJ, Daar ES, Eron J, Fletcher CV, Greninger AL, Hessinger D, Li JZ, Mailhot D, Wohl D, Chayakulkeeree M, Mendoza JLA, Elistratova P, Makinde O, Morgan G, Portsmouth S, Uehara T, Smith D, Currier JS
published in: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
information resource reference: Ensitrelvir for the Treatment of Nonhospitalized Adults with COVID-19: Results from the SCORPIO-HR, Phase 3, Randomized, Double-blind, Placebo-Controlled Trial. Clin Infect Dis. 2025 Jul 18; 80(6):1235-1244.
journal title abbreviation: Clin Infect Dis
publication date: 2025-07-18T00:00:00
year: 2025
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 691752
type: Authorship
author rank in publication: 2
linked author: Hughes, Michael
linked information resource: Bone mineral density effects of randomized regimen and nucleoside reverse transcriptase inhibitor selection from ACTG A5142.

Bone mineral density effects of randomized regimen and nucleoside reverse transcriptase inhibitor selection from ACTG A5142.
PubMed Identifier: 24144899
author list: Huang JS, Hughes MD, Riddler SA, Haubrich RH
published in: HIV clinical trials
information resource reference: Bone mineral density effects of randomized regimen and nucleoside reverse transcriptase inhibitor selection from ACTG A5142. HIV Clin Trials. 2013 Sep-Oct; 14(5):224-34.
journal title abbreviation: HIV Clin Trials
publication date: 2013-09-01T00:00:00
year: 2013
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 208376
type: Authorship
author rank in publication: 5
linked author: Hughes, Michael
linked information resource: Pharmacokinetics of saquinavir plus low-dose ritonavir in human immunodeficiency virus-infected pregnant women.

Authorship 1751657
type: Authorship
author rank in publication: 13
linked author: Hughes, Michael
linked information resource: Implementation of a seamless phase 2/3 study design in the setting of an emergent infectious disease pandemic: Lessons learned from the ACTIV-2 platform COVID-19 treatment trial.

Authorship 1751521
type: Authorship
author rank in publication: 14
linked author: Hughes, Michael
linked information resource: Predictive markers for sustained viral suppression on dual bNAbs during ART interruption in children.

Implementation of a seamless phase 2/3 study design in the setting of an emergent infectious disease pandemic: Lessons learned from the ACTIV-2 platform COVID-19 treatment trial.
PubMed Identifier: 40147543
author list: Giganti MJ, Chew KW, Moser C, Eron JJ, Pinilla M, Li JZ, Ritz J, Javan AC, Wohl DA, Daar ES, Currier JS, Smith DM, Hughes MD
published in: Contemporary clinical trials
information resource reference: Implementation of a seamless phase 2/3 study design in the setting of an emergent infectious disease pandemic: Lessons learned from the ACTIV-2 platform COVID-19 treatment trial. Contemp Clin Trials. 2025 Jun; 153:107887.
journal title abbreviation: Contemp Clin Trials
publication date: 2025-03-25T00:00:00
year: 2025
type: Academic Article
type: Article
type: Document
type: Information Resource

Predictive markers for sustained viral suppression on dual bNAbs during ART interruption in children.
PubMed Identifier: 40136003
author list: Banga J, Nelson BS, Ajibola G, Mohammed T, Maphorisa C, Boleo C, Moyo S, Batlang O, Sakoi-Mosetlhi M, Maswabi K, Holme MP, Powis KM, Lockman S, Hughes MD, Makhema J, Kuritzkes DR, Litcherfeld M, Shapiro R
published in: Journal of acquired immune deficiency syndromes (1999)
information resource reference: Predictive markers for sustained viral suppression on dual bNAbs during ART interruption in children. J Acquir Immune Defic Syndr. 2025 Mar 26.
journal title abbreviation: J Acquir Immune Defic Syndr
publication date: 2025-03-26T00:00:00
year: 2025
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 695413
type: Authorship
author rank in publication: 3
linked author: Hughes, Michael
linked information resource: High hsCRP is associated with reduced lung function in structural firefighters.

High hsCRP is associated with reduced lung function in structural firefighters.
PubMed Identifier: 24115029
author list: Gaughan DM, Christiani DC, Hughes MD, Baur DM, Kobzik L, Wagner GR, Kales SN
published in: American journal of industrial medicine
information resource reference: High hsCRP is associated with reduced lung function in structural firefighters. Am J Ind Med. 2014 Jan; 57(1):31-7.
journal title abbreviation: Am J Ind Med
publication date: 2013-09-20T00:00:00
year: 2013
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 374491
type: Authorship
author rank in publication: 2
linked author: Hughes, Michael
linked information resource: Use of historical marker data for assessing treatment effects in phase I/II trials when subject selection is determined by baseline marker level.

Authorship 180863
type: Authorship
author rank in publication: 1
linked author: Hughes, Michael
linked information resource: Stopping rules and estimation problems in clinical trials.

Authorship 1753390
type: Authorship
author rank in publication: 3
linked author: Hughes, Michael
linked information resource: Precision medicine evaluation of heterogeneity of treatment effect for a time-to-event outcome with application in a trial of Initial treatment for people living with HIV.

Precision medicine evaluation of heterogeneity of treatment effect for a time-to-event outcome with application in a trial of Initial treatment for people living with HIV.
PubMed Identifier: 40400339
author list: Zheng Y, Currier JS, Hughes MD
published in: Clinical trials (London, England)
information resource reference: Precision medicine evaluation of heterogeneity of treatment effect for a time-to-event outcome with application in a trial of Initial treatment for people living with HIV. Clin Trials. 2025 Oct; 22(5):559-570.
journal title abbreviation: Clin Trials
publication date: 2025-05-22T00:00:00
year: 2025
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 702854
type: Authorship
author rank in publication: 16
linked author: Hughes, Michael
linked information resource: Outcomes among HIV-1 infected individuals first starting antiretroviral therapy with concurrent active TB or other AIDS-defining disease.

Authorship 701662
type: Authorship
author rank in publication: 6
linked author: Hughes, Michael
linked information resource: Identification and purification of a protein that induces production of the Lactobacillus acidophilus bacteriocin lactacin B.

Identification and purification of a protein that induces production of the Lactobacillus acidophilus bacteriocin lactacin B.
PubMed Identifier: 7986029
author list: Barefoot SF, Chen YR, Hughes TA, Bodine AB, Shearer MY, Hughes MD
published in: Applied and environmental microbiology
information resource reference: Identification and purification of a protein that induces production of the Lactobacillus acidophilus bacteriocin lactacin B. Appl Environ Microbiol. 1994 Oct; 60(10):3522-8.
journal title abbreviation: Appl Environ Microbiol
publication date: 1994-10-01T00:00:00
year: 1994
type: Academic Article
type: Article
type: Document
type: Information Resource

Outcomes among HIV-1 infected individuals first starting antiretroviral therapy with concurrent active TB or other AIDS-defining disease.
PubMed Identifier: 24391801
author list: Périssé AR, Smeaton L, Chen Y, La Rosa A, Walawander A, Nair A, Grinsztejn B, Santos B, Kanyama C, Hakim J, Nyirenda M, Kumarasamy N, Lalloo UG, Flanigan T, Campbell TB, Hughes MD
published in: PloS one
information resource reference: Outcomes among HIV-1 infected individuals first starting antiretroviral therapy with concurrent active TB or other AIDS-defining disease. PLoS One. 2013; 8(12):e83643.
journal title abbreviation: PLoS One
publication date: 2013-12-31T00:00:00
year: 2013
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 245248
type: Authorship
author rank in publication: 1
linked author: Hughes, Michael
linked information resource: HIF-2alpha downregulation in the absence of functional VHL is not sufficient for renal cell differentiation.

Authorship 301750
type: Authorship
author rank in publication: 1
linked author: Hughes, Michael
linked information resource: Evaluating surrogate markers.

Authorship 722051
type: Authorship
author rank in publication: 8
linked author: Hughes, Michael
linked information resource: Low-frequency nevirapine (NVP)-resistant HIV-1 variants are not associated with failure of antiretroviral therapy in women without prior exposure to single-dose NVP.

Authorship 722868
type: Authorship
author rank in publication: 2
linked author: Hughes, Michael
linked information resource: Within- and between-child variation in repeated urinary pesticide metabolite measurements over a 1-year period.

Authorship 721993
type: Authorship
author rank in publication: 17
linked author: Hughes, Michael
linked information resource: Definitions and validation criteria for biomarkers and surrogate endpoints: development and testing of a quantitative hierarchical levels of evidence schema.

Definitions and validation criteria for biomarkers and surrogate endpoints: development and testing of a quantitative hierarchical levels of evidence schema.
PubMed Identifier: 17343307
author list: Lassere MN, Johnson KR, Boers M, Tugwell P, Brooks P, Simon L, Strand V, Conaghan PG, Ostergaard M, Maksymowych WP, Landewe R, Bresnihan B, Tak PP, Wakefield R, Mease P, Bingham CO, Hughes M, Altman D, Buyse M, Galbraith S, Wells G
published in: The Journal of rheumatology
information resource reference: Definitions and validation criteria for biomarkers and surrogate endpoints: development and testing of a quantitative hierarchical levels of evidence schema. J Rheumatol. 2007 Mar; 34(3):607-15.
journal title abbreviation: J Rheumatol
publication date: 2007-03-01T00:00:00
year: 2007
type: Academic Article
type: Article
type: Document
type: Information Resource

Within- and between-child variation in repeated urinary pesticide metabolite measurements over a 1-year period.
PubMed Identifier: 24325925
author list: Attfield KR, Hughes MD, Spengler JD, Lu C
published in: Environmental health perspectives
information resource reference: Within- and between-child variation in repeated urinary pesticide metabolite measurements over a 1-year period. Environ Health Perspect. 2014 Feb; 122(2):201-6.
journal title abbreviation: Environ Health Perspect
publication date: 2013-12-10T00:00:00
year: 2013
type: Academic Article
type: Article
type: Document
type: Information Resource

Low-frequency nevirapine (NVP)-resistant HIV-1 variants are not associated with failure of antiretroviral therapy in women without prior exposure to single-dose NVP.
PubMed Identifier: 24443547
author list: Boltz VF, Bao Y, Lockman S, Halvas EK, Kearney MF, McIntyre JA, Schooley RT, Hughes MD, Coffin JM, Mellors JW
published in: The Journal of infectious diseases
information resource reference: Low-frequency nevirapine (NVP)-resistant HIV-1 variants are not associated with failure of antiretroviral therapy in women without prior exposure to single-dose NVP. J Infect Dis. 2014 Mar 01; 209(5):703-10.
journal title abbreviation: J Infect Dis
publication date: 2014-01-16T00:00:00
year: 2014
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 246898
type: Authorship
author rank in publication: 2
linked author: Hughes, Michael
linked information resource: Estimation issues in clinical trials and overviews.

Authorship 312878
type: Authorship
author rank in publication: 2
linked author: Hughes, Michael
linked information resource: Antiretroviral regimens in pregnancy and breast-feeding in Botswana.

Authorship 729451
type: Authorship
author rank in publication: 2
linked author: Hughes, Michael
linked information resource: Cardiovascular disease risk factors in HIV-infected women after initiation of lopinavir/ritonavir- and nevirapine-based antiretroviral therapy in Sub-Saharan Africa: A5208 (OCTANE).

Cardiovascular disease risk factors in HIV-infected women after initiation of lopinavir/ritonavir- and nevirapine-based antiretroviral therapy in Sub-Saharan Africa: A5208 (OCTANE).
PubMed Identifier: 24562349
author list: Shaffer D, Hughes MD, Sawe F, Bao Y, Moses A, Hogg E, Lockman S, Currier J
published in: Journal of acquired immune deficiency syndromes (1999)
information resource reference: Cardiovascular disease risk factors in HIV-infected women after initiation of lopinavir/ritonavir- and nevirapine-based antiretroviral therapy in Sub-Saharan Africa: A5208 (OCTANE). J Acquir Immune Defic Syndr. 2014 Jun 01; 66(2):155-63.
journal title abbreviation: J Acquir Immune Defic Syndr
publication date: 2014-06-01T00:00:00
year: 2014
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1779036
type: Authorship
author rank in publication: 9
linked author: Hughes, Michael
linked information resource: Modeling the emergence of viral resistance for SARS-CoV-2 during treatment with an anti-spike monoclonal antibody.

Authorship 1780895
type: Authorship
author rank in publication: 9
linked author: Hughes, Michael
linked information resource: The statistical design and analysis of pandemic platform trials: Implications for the future.

Authorship 1784487
type: Authorship
author rank in publication: 9
linked author: Hughes, Michael
linked information resource: Erratum: The statistical design and analysis of pandemic platform trials: Implications for the future - CORRIGENDUM.

Authorship 1772135
type: Authorship
author rank in publication: 4
linked author: Hughes, Michael
linked information resource: Ensitrelvir for the Treatment of Nonhospitalized Adults with COVID-19: Results from the SCORPIO-HR, Phase 3, Randomized, Double-blind, Placebo-Controlled Trial.

Authorship 1777776
type: Authorship
author rank in publication: 17
linked author: Hughes, Michael
linked information resource: Safety and Efficacy of SAB-185 for Nonhospitalized Adults With COVID-19: A Randomized Clinical Trial.

Authorship 1793117
type: Authorship
author rank in publication: 2
linked author: Hughes, Michael
linked information resource: Protecting households on exposure to newly diagnosed index multidrug-resistant tuberculosis patients: Study protocol for the PHOENIx phase 3 clinical trial.

Authorship 1811695
type: Authorship
author rank in publication: 9
linked author: Hughes, Michael
linked information resource: ACTIV trials: Lessons learned in trial design in the setting of an emergent pandemic.

Authorship 1816661
type: Authorship
author rank in publication: 7
linked author: Hughes, Michael
linked information resource: Long-Term Clinical, Immunologic, and Viral Reservoir Outcomes in Children Treated With VRC01LS and 10-1074 Monoclonal Antibodies in the Tatelo Study.

Authorship 1817248
type: Authorship
author rank in publication: 5
linked author: Hughes, Michael
linked information resource: Virological and drug-resistance outcomes for people living with HIV initiating or switching to tenofovir, lamivudine, and dolutegravir in six PEPFAR-supported countries: a prospective cohort study.

Authorship 1822380
type: Authorship
author rank in publication: 19
linked author: Hughes, Michael
linked information resource: The Choice of Viral Load End Point in Early Phase Trials of COVID-19 Treatments Aiming to Reduce 28-Day Hospitalization and/or Death.

Authorship 1832919
type: Authorship
author rank in publication: 6
linked author: Hughes, Michael
linked information resource: Evaluating Treatment Effects with Patient-Response-Related Outcomes in Comparative Clinical Trials.

Authorship 1847051
type: Authorship
author rank in publication: 19
linked author: Hughes, Michael
linked information resource: Evaluating Viral Load Sampling Schemes and Swabbing Methods for Optimal Surrogacy.

Authorship 1852712
type: Authorship
author rank in publication: 12
linked author: Hughes, Michael
linked information resource: Viral shedding and symptom severity across populations during acute COVID in the ACTIV-2 study.

Authorship 1853154
type: Authorship
author rank in publication: 3
linked author: Hughes, Michael
linked information resource: Effectiveness of Double-Dose Dolutegravir in People Receiving Rifampin-based Tuberculosis Treatment: An Observational, Cohort Study of People With HIV From 6 Countries.

Evaluating Treatment Effects with Patient-Response-Related Outcomes in Comparative Clinical Trials.
PubMed Identifier: 41288427
author list: Mao L, Tian L, Huang B, Richardson PG, Ludmir EB, Hughes MD, Wei LJ
published in: NEJM evidence
information resource reference: Evaluating Treatment Effects with Patient-Response-Related Outcomes in Comparative Clinical Trials. NEJM Evid. 2025 Dec; 4(12):EVIDctw2400349.
journal title abbreviation: NEJM Evid
publication date: 2025-11-25T00:00:00
year: 2025
type: Academic Article
type: Article
type: Document
type: Information Resource

Effectiveness of Double-Dose Dolutegravir in People Receiving Rifampin-based Tuberculosis Treatment: An Observational, Cohort Study of People With HIV From 6 Countries.
PubMed Identifier: 38739755
author list: Shah NS, Kityo C, Hughes MD, McCarthy C, Wallis CL, Hosseinipour MC, Langat D, Nyirenda M, Rassool M, Dawson R, Joseph Y, Some F, Mngqibisa R, Mukwekwerere PG, Woolley E, Godfrey C, Manabe YC, Mellors JW, Flexner C, Maartens G
published in: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
information resource reference: Effectiveness of Double-Dose Dolutegravir in People Receiving Rifampin-based Tuberculosis Treatment: An Observational, Cohort Study of People With HIV From 6 Countries. Clin Infect Dis. 2025 02 05; 80(1):137-143.
journal title abbreviation: Clin Infect Dis
publication date: 2025-02-05T00:00:00
year: 2025
type: Academic Article
type: Article
type: Document
type: Information Resource

ACTIV trials: Lessons learned in trial design in the setting of an emergent pandemic.
PubMed Identifier: 39478775
author list: Keshtkar-Jahromi M, Anstrom KJ, Barkauskas C, Brown SM, Daar ES, Fischer W, Gibbs KW, Higgs ES, Hughes MD, Jagannathan P, LaVange L, Lindsell CJ, Nayak SU, Paredes R, Parmar M, Peltan ID, Proschan M, Shotwell MS, Vock DM, Yokum T, Adam SJ
published in: Journal of clinical and translational science
information resource reference: ACTIV trials: Lessons learned in trial design in the setting of an emergent pandemic. J Clin Transl Sci. 2024; 8(1):e151.
journal title abbreviation: J Clin Transl Sci
publication date: 2024-10-15T00:00:00
year: 2024
type: Academic Article
type: Article
type: Document
type: Information Resource

Protecting households on exposure to newly diagnosed index multidrug-resistant tuberculosis patients: Study protocol for the PHOENIx phase 3 clinical trial.
PubMed Identifier: 40992540
author list: Kendall MA, Hughes MD, Kim S, Aaron LA, Naini L, Suryavanshi N, Shah NS, Rouzier V, Hafkin J, Sise T, Beck J, Heckman BE, Haberer JE, Harrington M, Scarsi KK, Hesseling AC, Swindells S, Churchyard GJ, Gupta A
published in: Contemporary clinical trials
information resource reference: Protecting households on exposure to newly diagnosed index multidrug-resistant tuberculosis patients: Study protocol for the PHOENIx phase 3 clinical trial. Contemp Clin Trials. 2025 Nov; 158:108084.
journal title abbreviation: Contemp Clin Trials
publication date: 2025-09-22T00:00:00
year: 2025
type: Academic Article
type: Article
type: Document
type: Information Resource

Evaluating Viral Load Sampling Schemes and Swabbing Methods for Optimal Surrogacy.
PubMed Identifier: 40832932
author list: Mateja A, Chu E, Murray TA, Bramante CT, Moser C, Givens N, Abdelghany M, Blair C, Chen S, Lat PK, Harari O, Kallewaard NL, Macpherson LF, Boulware DR, Suñer C, Mitjà O, Adam SJ, De Gruttola V, Hughes MD, Rubin D, Smith DM, Potter GE
published in: The Journal of infectious diseases
information resource reference: Evaluating Viral Load Sampling Schemes and Swabbing Methods for Optimal Surrogacy. J Infect Dis. 2026 Feb 18; 233(2):e585-e586.
journal title abbreviation: J Infect Dis
publication date: 2026-02-18T00:00:00
year: 2026
type: Academic Article
type: Article
type: Document
type: Information Resource

Viral shedding and symptom severity across populations during acute COVID in the ACTIV-2 study.
PubMed Identifier: 41674614
author list: Kung E, Deo R, Choudhary MC, Chew KW, Evering TH, Ignacio RB, Jagannathan P, Flynn JP, Regan J, Moser C, Giganti MJ, Hughes MD, Ritz J, Javan AC, Greninger AL, Singh U, Fischer W, Daar ES, Wohl DA, Eron JJ, Currier JS, Coombs RW, Smith DM, Li JZ
published in: medRxiv : the preprint server for health sciences
information resource reference: Viral shedding and symptom severity across populations during acute COVID in the ACTIV-2 study. medRxiv. 2026 Feb 03.
journal title abbreviation: medRxiv
publication date: 2026-02-03T00:00:00
year: 2026
type: Academic Article
type: Article
type: Document
type: Information Resource

The Choice of Viral Load End Point in Early Phase Trials of COVID-19 Treatments Aiming to Reduce 28-Day Hospitalization and/or Death.
PubMed Identifier: 40461945
author list: Mateja A, Chu E, Murray TA, Bramante CT, Moser C, Givens N, Abdelghany M, Blair C, Chen S, Lat PK, Harari O, Kallewaard NL, Macpherson LF, Boulware DR, Suñer C, Mitjà O, Adam SJ, De Gruttola V, Hughes MD, Rubin D, Smith DM, Potter GE
published in: The Journal of infectious diseases
information resource reference: The Choice of Viral Load End Point in Early Phase Trials of COVID-19 Treatments Aiming to Reduce 28-Day Hospitalization and/or Death. J Infect Dis. 2025 Jul 30; 232(1):60-68.
journal title abbreviation: J Infect Dis
publication date: 2025-07-30T00:00:00
year: 2025
type: Academic Article
type: Article
type: Document
type: Information Resource

Long-Term Clinical, Immunologic, and Viral Reservoir Outcomes in Children Treated With VRC01LS and 10-1074 Monoclonal Antibodies in the Tatelo Study.
PubMed Identifier: 41078080
author list: Ajibola G, Nelson BS, Niesar A, Hong S, Lancien M, Holme MP, Hughes MD, Yin DE, Jean-Philippe P, Moyo S, Batlang O, Sakoi M, Maphorisa C, Mohammed T, Lockman S, Makhema J, Kuritzkes DR, Lichterfeld M, Shapiro RL
published in: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
information resource reference: Long-Term Clinical, Immunologic, and Viral Reservoir Outcomes in Children Treated With VRC01LS and 10-1074 Monoclonal Antibodies in the Tatelo Study. Clin Infect Dis. 2026 Feb 25; 82(2):e278-e285.
journal title abbreviation: Clin Infect Dis
publication date: 2026-02-25T00:00:00
year: 2026
type: Academic Article
type: Article
type: Document
type: Information Resource

Virological and drug-resistance outcomes for people living with HIV initiating or switching to tenofovir, lamivudine, and dolutegravir in six PEPFAR-supported countries: a prospective cohort study.
PubMed Identifier: 41314742
author list: Marc JB, McCarthy C, Wallis CL, Kityo C, Hughes MD, Godfrey C, Shah NS, Parikh UM, Maartens G, Kanyike F, Van Schalkwyk M, Kihumuro RB, Asiimwe P, Tsikhutsu I, Munyanga C, Some FF, Joseph Y, Flowers T, Mohapi L, Samaneka WP, Mponda K, Rassool MS, Pierre S, Woolley E, Manabe YC, Mellors JW, Flexner C, Koenig SP, Mngqibisa R
published in: The lancet. HIV
information resource reference: Virological and drug-resistance outcomes for people living with HIV initiating or switching to tenofovir, lamivudine, and dolutegravir in six PEPFAR-supported countries: a prospective cohort study. Lancet HIV. 2025 Dec; 12(12):e836-e849.
journal title abbreviation: Lancet HIV
publication date: 2025-12-01T00:00:00
year: 2025
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 737328
type: Authorship
author rank in publication: 3
linked author: Hughes, Michael
linked information resource: Arterial stiffness, oxidative stress, and smoke exposure in wildland firefighters.

Arterial stiffness, oxidative stress, and smoke exposure in wildland firefighters.
PubMed Identifier: 24909863
author list: Gaughan DM, Siegel PD, Hughes MD, Chang CY, Law BF, Campbell CR, Richards JC, Kales SF, Chertok M, Kobzik L, Nguyen PS, O'Donnell CR, Kiefer M, Wagner GR, Christiani DC
published in: American journal of industrial medicine
information resource reference: Arterial stiffness, oxidative stress, and smoke exposure in wildland firefighters. Am J Ind Med. 2014 Jul; 57(7):748-56.
journal title abbreviation: Am J Ind Med
publication date: 2014-06-06T00:00:00
year: 2014
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 329587
type: Authorship
author rank in publication: 2
linked author: Hughes, Michael
linked information resource: Analysis of uncontrolled treatment changes in HIV clinical trails.

Vitamin D insufficiency in HIV-infected pregnant women receiving antiretroviral therapy is not associated with morbidity, mortality or growth impairment in their uninfected infants in Botswana.
PubMed Identifier: 25037041
author list: Powis K, Lockman S, Smeaton L, Hughes MD, Fawzi W, Ogwu A, Moyo S, van Widenfelt E, von Oettingen J, Makhema J, Essex M, Shapiro RL
published in: The Pediatric infectious disease journal
information resource reference: Vitamin D insufficiency in HIV-infected pregnant women receiving antiretroviral therapy is not associated with morbidity, mortality or growth impairment in their uninfected infants in Botswana. Pediatr Infect Dis J. 2014 Nov; 33(11):1141-7.
journal title abbreviation: Pediatr Infect Dis J
publication date: 2014-11-01T00:00:00
year: 2014
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 359882
type: Authorship
author rank in publication: 1
linked author: Hughes, Michael
linked information resource: Practical issues arising in an exploratory analysis evaluating progression-free survival as a surrogate endpoint for overall survival in advanced colorectal cancer.

Authorship 741610
type: Authorship
author rank in publication: 10
linked author: Hughes, Michael
linked information resource: Renal events among women treated with tenofovir/emtricitabine in combination with either lopinavir/ritonavir or nevirapine.

Authorship 743951
type: Authorship
author rank in publication: 9
linked author: Hughes, Michael
linked information resource: Predictors of suboptimal CD4 response among women achieving virologic suppression in a randomized antiretroviral treatment trial, Africa.

Renal events among women treated with tenofovir/emtricitabine in combination with either lopinavir/ritonavir or nevirapine.
PubMed Identifier: 24445367
author list: Mwafongo A, Nkanaunena K, Zheng Y, Hogg E, Samaneka W, Mulenga L, Siika A, Currier J, Lockman S, Hughes MD, Hosseinipour M
published in: AIDS (London, England)
information resource reference: Renal events among women treated with tenofovir/emtricitabine in combination with either lopinavir/ritonavir or nevirapine. AIDS. 2014 May 15; 28(8):1135-42.
journal title abbreviation: AIDS
publication date: 2014-05-15T00:00:00
year: 2014
type: Academic Article
type: Article
type: Document
type: Information Resource

Predictors of suboptimal CD4 response among women achieving virologic suppression in a randomized antiretroviral treatment trial, Africa.
PubMed Identifier: 24938526
author list: Asmelash A, Zheng Y, Kaloustian KW, Shaffer D, Sawe F, Ogwu A, Salata R, Currier J, Hughes MD, Lockman S
published in: BMC infectious diseases
information resource reference: Predictors of suboptimal CD4 response among women achieving virologic suppression in a randomized antiretroviral treatment trial, Africa. BMC Infect Dis. 2014 Jun 17; 14:331.
journal title abbreviation: BMC Infect Dis
publication date: 2014-06-17T00:00:00
year: 2014
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 401974
type: Authorship
author rank in publication: 6
linked author: Hughes, Michael
linked information resource: Assessing human immunodeficiency virus type 1 tropism: Comparison of assays using replication-competent virus versus plasma-derived pseudotyped virions.

Director of the Center for Biostatistics in AIDS Research
position in department: Biostatistics
position in division: https://connects.catalyst.harvard.edu/Profiles/profile/1229413
sort order: 2
type: Position
HR job title: Director of the Center for Biostatistics in AIDS Research
position in organization: Harvard T.H. Chan School of Public Health

Professor of Computational Biology and Bioinformatics
is primary position: true
position in department: Biostatistics
position in division: https://connects.catalyst.harvard.edu/Profiles/profile/1229413
sort order: 1
type: Position
HR job title: Professor of Computational Biology and Bioinformatics
position in organization: Harvard T.H. Chan School of Public Health

Senior Research Scientist
is primary position: true
position in department: Center for Biostatistics in AIDS Research
position in division: https://connects.catalyst.harvard.edu/Profiles/profile/1229413
sort order: 1
type: Position
HR job title: Senior Research Scientist
position in organization: Harvard T.H. Chan School of Public Health

Adjunct Professor of Biostatistics
is primary position: true
position in department: Biostatistics
position in division: https://connects.catalyst.harvard.edu/Profiles/profile/1229413
sort order: 1
type: Position
HR job title: Adjunct Professor of Biostatistics
position in organization: Harvard T.H. Chan School of Public Health

Clarence James Gamble Professor of Biostatistics, Population, and Data Science
is primary position: true
position in department: Biostatistics
position in division: https://connects.catalyst.harvard.edu/Profiles/profile/1229413
sort order: 1
type: Position
HR job title: Clarence James Gamble Professor of Biostatistics, Population, and Data Science
position in organization: Harvard T.H. Chan School of Public Health

Professor of Statistical Computing, Emeritus
is primary position: true
position in department: Biostatistics
position in division: https://connects.catalyst.harvard.edu/Profiles/profile/1229413
sort order: 1
type: Position
HR job title: Professor of Statistical Computing, Emeritus
position in organization: Harvard T.H. Chan School of Public Health

Professor of Immunology and Infectious Diseases
is primary position: true
position in department: Immunology and Infectious Diseases
position in division: https://connects.catalyst.harvard.edu/Profiles/profile/1229413
sort order: 1
type: Position
HR job title: Professor of Immunology and Infectious Diseases
position in organization: Harvard T.H. Chan School of Public Health

Professor of Biostatistics
is primary position: true
position in department: Biostatistics
position in division: https://connects.catalyst.harvard.edu/Profiles/profile/1229413
sort order: 1
type: Position
HR job title: Professor of Biostatistics
position in organization: Harvard T.H. Chan School of Public Health

Associate Professor of Medicine
is primary position: true
position in department: Medicine
position in division: Infectious Disease
sort order: 1
type: Position
HR job title: Associate Professor of Medicine
position in organization: Brigham and Women's Hospital

Professor of Medicine
is primary position: true
position in department: Medicine
position in division: Infectious Disease
sort order: 1
type: Position
HR job title: Professor of Medicine
position in organization: Brigham and Women's Hospital

Harvey V. Fineberg Professor of Public Health, Emerita
is primary position: true
position in department: Biostatistics
position in division: https://connects.catalyst.harvard.edu/Profiles/profile/1229413
sort order: 1
type: Position
HR job title: Harvey V. Fineberg Professor of Public Health, Emerita
position in organization: Harvard T.H. Chan School of Public Health

Professor of Medicine
is primary position: true
position in department: Medicine
position in division: Infectious Disease
sort order: 1
type: Position
HR job title: Professor of Medicine
position in organization: Beth Israel Deaconess Medical Center

Richard Saltonstall Professor of Population Sciences, and Professor of Nutrition, Epidemiology, and Global Health
is primary position: true
position in department: Global Health and Population
position in division: https://connects.catalyst.harvard.edu/Profiles/profile/1229413
sort order: 1
type: Position
HR job title: Richard Saltonstall Professor of Population Sciences, and Professor of Nutrition, Epidemiology, and Global Health
position in organization: Harvard T.H. Chan School of Public Health

Associate Professor of Pediatrics
is primary position: true
position in department: Pediatrics
position in division: Infectious Disease
sort order: 1
type: Position
HR job title: Associate Professor of Pediatrics
position in organization: Massachusetts General Hospital

Authorship 752590
type: Authorship
author rank in publication: 2
linked author: Hughes, Michael
linked information resource: Antiretroviral therapy and efficacy after virologic failure on first-line boosted protease inhibitor regimens.

Authorship 747203
type: Authorship
author rank in publication: 13
linked author: Hughes, Michael
linked information resource: Exposures and cross-shift lung function declines in wildland firefighters.

Authorship 749123
type: Authorship
author rank in publication: 14
linked author: Hughes, Michael
linked information resource: Moving beyond the hazard ratio in quantifying the between-group difference in survival analysis.

Antiretroviral therapy and efficacy after virologic failure on first-line boosted protease inhibitor regimens.
PubMed Identifier: 24842909
author list: Zheng Y, Hughes MD, Lockman S, Benson CA, Hosseinipour MC, Campbell TB, Gulick RM, Daar ES, Sax PE, Riddler SA, Haubrich R, Salata RA, Currier JS
published in: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
information resource reference: Antiretroviral therapy and efficacy after virologic failure on first-line boosted protease inhibitor regimens. Clin Infect Dis. 2014 Sep 15; 59(6):888-96.
journal title abbreviation: Clin Infect Dis
publication date: 2014-05-19T00:00:00
year: 2014
type: Academic Article
type: Article
type: Document
type: Information Resource

Moving beyond the hazard ratio in quantifying the between-group difference in survival analysis.
PubMed Identifier: 24982461
author list: Uno H, Claggett B, Tian L, Inoue E, Gallo P, Miyata T, Schrag D, Takeuchi M, Uyama Y, Zhao L, Skali H, Solomon S, Jacobus S, Hughes M, Packer M, Wei LJ
published in: Journal of clinical oncology : official journal of the American Society of Clinical Oncology
information resource reference: Moving beyond the hazard ratio in quantifying the between-group difference in survival analysis. J Clin Oncol. 2014 Aug 01; 32(22):2380-5.
journal title abbreviation: J Clin Oncol
publication date: 2014-06-30T00:00:00
year: 2014
type: Academic Article
type: Article
type: Document
type: Information Resource

Exposures and cross-shift lung function declines in wildland firefighters.
PubMed Identifier: 24568319
author list: Gaughan DM, Piacitelli CA, Chen BT, Law BF, Virji MA, Edwards NT, Enright PL, Schwegler-Berry DE, Leonard SS, Wagner GR, Kobzik L, Kales SN, Hughes MD, Christiani DC, Siegel PD, Cox-Ganser JM, Hoover MD
published in: Journal of occupational and environmental hygiene
information resource reference: Exposures and cross-shift lung function declines in wildland firefighters. J Occup Environ Hyg. 2014; 11(9):591-603.
journal title abbreviation: J Occup Environ Hyg
publication date: 2014-01-01T00:00:00
year: 2014
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 527292
type: Authorship
author rank in publication: 11
linked author: Hughes, Michael
linked information resource: Quantitative deep sequencing reveals dynamic HIV-1 escape and large population shifts during CCR5 antagonist therapy in vivo.

Authorship 53377
type: Authorship
author rank in publication: 7
linked author: Hughes, Michael
linked information resource: Relationship of plasma HIV-1 RNA dynamics to baseline factors and virological responses to highly active antiretroviral therapy in adolescents (aged 12-22 years) infected through high-risk behavior.

Authorship 757503
type: Authorship
author rank in publication: 2
linked author: Hughes, Michael
linked information resource: Laparoscopic-assisted small bowel resection for treatment of adult small bowel intussusception: a case report.

Authorship 757470
type: Authorship
author rank in publication: 5
linked author: Hughes, Michael
linked information resource: Analysis of diagnostic error in paid malpractice claims with substandard care in a large healthcare system.

Authorship 757640
type: Authorship
author rank in publication: 7
linked author: Hughes, Michael
linked information resource: Control of a two-decade endemic situation with carbapenem-resistant Acinetobacter baumannii: electronic dissemination of a bundle of interventions.

Authorship 757844
type: Authorship
author rank in publication: 1
linked author: Hughes, Michael
linked information resource: Stroke and thromboembolism in atrial fibrillation: a systematic review of stroke risk factors, risk stratification schema and cost effectiveness data.

Authorship 758445
type: Authorship
author rank in publication: 5
linked author: Hughes, Michael
linked information resource: Guidelines for data and safety monitoring for clinical trials not requiring traditional data monitoring committees.

Authorship 758453
type: Authorship
author rank in publication: 2
linked author: Hughes, Michael
linked information resource: https://connects.catalyst.harvard.edu/Profiles/profile/34665606

Analysis of diagnostic error in paid malpractice claims with substandard care in a large healthcare system.
PubMed Identifier: 16351028
author list: Holohan TV, Colestro J, Grippi J, Converse J, Hughes M
published in: Southern medical journal
information resource reference: Analysis of diagnostic error in paid malpractice claims with substandard care in a large healthcare system. South Med J. 2005 Nov; 98(11):1083-7.
journal title abbreviation: South Med J
publication date: 2005-11-01T00:00:00
year: 2005
type: Academic Article
type: Article
type: Document
type: Information Resource

Control of a two-decade endemic situation with carbapenem-resistant Acinetobacter baumannii: electronic dissemination of a bundle of interventions.
PubMed Identifier: 24773784
author list: Munoz-Price LS, Carling P, Cleary T, Fajardo-Aquino Y, DePascale D, Jimenez A, Hughes M, Namias N, Pizano L, Kett DH, Arheart K
published in: American journal of infection control
information resource reference: Control of a two-decade endemic situation with carbapenem-resistant Acinetobacter baumannii: electronic dissemination of a bundle of interventions. Am J Infect Control. 2014 May; 42(5):466-71.
journal title abbreviation: Am J Infect Control
publication date: 2014-05-01T00:00:00
year: 2014
type: Academic Article
type: Article
type: Document
type: Information Resource

Guidelines for data and safety monitoring for clinical trials not requiring traditional data monitoring committees.
PubMed Identifier: 16895048
author list: Dixon DO, Freedman RS, Herson J, Hughes M, Kim K, Silverman MH, Tangen CM
published in: Clinical trials (London, England)
information resource reference: Guidelines for data and safety monitoring for clinical trials not requiring traditional data monitoring committees. Clin Trials. 2006; 3(3):314-9.
journal title abbreviation: Clin Trials
publication date: 2006-01-01T00:00:00
year: 2006
type: Academic Article
type: Article
type: Document
type: Information Resource

https://connects.catalyst.harvard.edu/Profiles/profile/34665606
PubMed Identifier: 25222305
author list: Lindsey JC, Hughes MD, Violari A, Eshleman SH, Abrams EJ, Bwakura-Dangarembizi M, Barlow-Mosha L, Kamthunzi P, Sambo PM, Cotton MF, Moultrie H, Khadse S, Schimana W, Bobat R, Zimmer B, Petzold E, Mofenson LM, Jean-Philippe P, Palumbo P
published in: The Pediatric infectious disease journal
information resource reference: Predictors of virologic and clinical response to nevirapine versus lopinavir/ritonavir-based antiretroviral therapy in young children with and without prior nevirapine exposure for the prevention of mother-to-child HIV transmission. Pediatr Infect Dis J. 2014 Aug; 33(8):846-54.
journal title abbreviation: Pediatr Infect Dis J
publication date: 2014-08-01T00:00:00
year: 2014
type: Academic Article
type: Article
type: Document
type: Information Resource
label: Predictors of virologic and clinical response to nevirapine versus lopinavir/ritonavir-based antiretroviral therapy in young children with and without prior nevirapine exposure for the prevention of mother-to-child HIV transmission.

Stroke and thromboembolism in atrial fibrillation: a systematic review of stroke risk factors, risk stratification schema and cost effectiveness data.
PubMed Identifier: 18278178
author list: Hughes M, Lip GY
published in: Thrombosis and haemostasis
information resource reference: Stroke and thromboembolism in atrial fibrillation: a systematic review of stroke risk factors, risk stratification schema and cost effectiveness data. Thromb Haemost. 2008 Feb; 99(2):295-304.
journal title abbreviation: Thromb Haemost
publication date: 2008-02-01T00:00:00
year: 2008
type: Academic Article
type: Article
type: Document
type: Information Resource

Laparoscopic-assisted small bowel resection for treatment of adult small bowel intussusception: a case report.
PubMed Identifier: 19117512
author list: Stewart D, Hughes M, Hope WW
published in: Cases journal
information resource reference: Laparoscopic-assisted small bowel resection for treatment of adult small bowel intussusception: a case report. Cases J. 2008 Dec 31; 1(1):432.
journal title abbreviation: Cases J
publication date: 2008-12-31T00:00:00
year: 2008
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 385525
type: Authorship
author rank in publication: 13
linked author: Hughes, Michael
linked information resource: Virologic and immunologic outcomes after 24 weeks in HIV type 1-infected adolescents receiving highly active antiretroviral therapy.

Authorship 396422
type: Authorship
author rank in publication: 2
linked author: Hughes, Michael
linked information resource: Accelerated wound healing: multidisciplinary advances in the care of venous leg ulcers.

Authorship 768747
type: Authorship
author rank in publication: 4
linked author: Hughes, Michael
linked information resource: Vitamin D insufficiency in HIV-infected pregnant women receiving antiretroviral therapy is not associated with morbidity, mortality or growth impairment in their uninfected infants in Botswana.

Authorship 2318
type: Authorship
author rank in publication: 1
linked author: Hughes, Michael
linked information resource: Challenges in using observational studies to evaluate adverse effects of treatment.

Authorship 452886
type: Authorship
author rank in publication: 7
linked author: Hughes, Michael
linked information resource: Ritonavir-based highly active antiretroviral therapy in human immunodeficiency virus type 1-infected infants younger than 24 months of age.

Factors associated with lack of viral suppression at delivery among highly active antiretroviral therapy-naive women with HIV: a cohort study.
PubMed Identifier: 25599347
author list: Katz IT, Leister E, Kacanek D, Hughes MD, Bardeguez A, Livingston E, Stek A, Shapiro DE, Tuomala R
published in: Annals of internal medicine
information resource reference: Factors associated with lack of viral suppression at delivery among highly active antiretroviral therapy-naive women with HIV: a cohort study. Ann Intern Med. 2015 Jan 20; 162(2):90-9.
journal title abbreviation: Ann Intern Med
publication date: 2015-01-20T00:00:00
year: 2015
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 552303
type: Authorship
author rank in publication: 4
linked author: Hughes, Michael
linked information resource: https://connects.catalyst.harvard.edu/Profiles/profile/806563

An augmented SMS intervention to improve access to antenatal CD4 testing and ART initiation in HIV-infected pregnant women: a cluster randomized trial.
PubMed Identifier: 25693050
author list: Dryden-Peterson S, Bennett K, Hughes MD, Veres A, John O, Pradhananga R, Boyer M, Brown C, Sakyi B, van Widenfelt E, Keapoletswe K, Mine M, Moyo S, Asmelash A, Siedner M, Mmalane M, Shapiro RL, Lockman S
published in: PloS one
information resource reference: An augmented SMS intervention to improve access to antenatal CD4 testing and ART initiation in HIV-infected pregnant women: a cluster randomized trial. PLoS One. 2015; 10(2):e0117181.
journal title abbreviation: PLoS One
publication date: 2015-02-18T00:00:00
year: 2015
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 400521
type: Authorship
author rank in publication: 12
linked author: Hughes, Michael
linked information resource: Safety and efficacy of nevirapine- and efavirenz-based antiretroviral treatment in adults treated for TB-HIV co-infection in Botswana.

Authorship 428679
type: Authorship
author rank in publication: 4
linked author: Hughes, Michael
linked information resource: Neurodevelopmental functioning in HIV-infected infants and young children before and after the introduction of protease inhibitor-based highly active antiretroviral therapy.

Authorship 473836
type: Authorship
author rank in publication: 3
linked author: Hughes, Michael
linked information resource: Predictors and impact of patients lost to follow-up in a long-term randomized trial of immediate versus deferred antiretroviral treatment.

Authorship 45372
type: Authorship
author rank in publication: 9
linked author: Hughes, Michael
linked information resource: Meta-analysis of five randomized controlled trials comparing continuation of zidovudine versus switching to didanosine in HIV-infected individuals.

Authorship 502105
type: Authorship
author rank in publication: 4
linked author: Hughes, Michael
linked information resource: Intrahousehold allocation of energy intake among children under five years and their parents in rural Bangladesh.

Authorship 555647
type: Authorship
author rank in publication: 2
linked author: Hughes, Michael
linked information resource: Practical problems in interim analyses, with particular regard to estimation.

Authorship 429852
type: Authorship
author rank in publication: 3
linked author: Hughes, Michael
linked information resource: https://connects.catalyst.harvard.edu/Profiles/profile/745924

Authorship 285026
type: Authorship
author rank in publication: 5
linked author: Hughes, Michael
linked information resource: Response to vicriviroc in treatment-experienced subjects, as determined by an enhanced-sensitivity coreceptor tropism assay: reanalysis of AIDS clinical trials group A5211.

Authorship 469632
type: Authorship
author rank in publication: 2
linked author: Hughes, Michael
linked information resource: Adjusting for regression toward the mean when variables are normally distributed.

Authorship 521550
type: Authorship
author rank in publication: 10
linked author: Hughes, Michael
linked information resource: Statistical issues for HIV surrogate endpoints: point/counterpoint. An NIAID workshop.

Authorship 67686
type: Authorship
author rank in publication: 6
linked author: Hughes, Michael
linked information resource: Efficacy, tolerability and pharmacokinetics of two nelfinavir-based regimens in human immunodeficiency virus-infected children and adolescents: pediatric AIDS clinical trials group protocol 403.

Authorship 21387
type: Authorship
author rank in publication: 2
linked author: Hughes, Michael
linked information resource: https://connects.catalyst.harvard.edu/Profiles/profile/805857

Authorship 78872
type: Authorship
author rank in publication: 2
linked author: Hughes, Michael
linked information resource: Virologic and CD4 cell response to zidovudine or zidovudine and lamivudine following didanosine treatment of human immunodeficiency virus infection.

Authorship 29948
type: Authorship
author rank in publication: 3
linked author: Hughes, Michael
linked information resource: Neuromuscular function in HIV infection: analysis of a placebo-controlled combination antiretroviral trial. AIDS Clinical Group 175/801 Study Team.

Authorship 312808
type: Authorship
author rank in publication: 11
linked author: Hughes, Michael
linked information resource: Long-term effects of protease-inhibitor-based combination therapy on CD4 T-cell recovery in HIV-1-infected children and adolescents.

Authorship 312468
type: Authorship
author rank in publication: 3
linked author: Hughes, Michael
linked information resource: A comparison of bronchodilator therapy with or without inhaled corticosteroid therapy for obstructive airways disease. Dutch Chronic Non-Specific Lung Disease Study Group.

Authorship 215204
type: Authorship
author rank in publication: 2
linked author: Hughes, Michael
linked information resource: Dynamic calibration of pharmacokinetic parameters in dose-finding studies.

Authorship 214746
type: Authorship
author rank in publication: 1
linked author: Hughes, Michael
linked information resource: Prediction of short-term survival with an application in primary biliary cirrhosis.

Authorship 431305
type: Authorship
author rank in publication: 9
linked author: Hughes, Michael
linked information resource: Safety and pharmacokinetics of nelfinavir coadministered with zidovudine and lamivudine in infants during the first 6 weeks of life.

Authorship 272646
type: Authorship
author rank in publication: 2
linked author: Hughes, Michael
linked information resource: The prevalence of pain in pediatric human immunodeficiency virus/acquired immunodeficiency syndrome as reported by participants in the Pediatric Late Outcomes Study (PACTG 219).

Authorship 334457
type: Authorship
author rank in publication: 2
linked author: Hughes, Michael
linked information resource: Predictors of virologic and clinical outcomes in HIV-1-infected patients receiving concurrent treatment with indinavir, zidovudine, and lamivudine. AIDS Clinical Trials Group Protocol 320.

Authorship 400896
type: Authorship
author rank in publication: 7
linked author: Hughes, Michael
linked information resource: Long-term increase in CD4+ T-cell counts during combination antiretroviral therapy for HIV-1 infection.

Authorship 488795
type: Authorship
author rank in publication: 6
linked author: Hughes, Michael
linked information resource: Differences between women and men in adverse events and CD4+ responses to nucleoside analogue therapy for HIV infection. The Aids Clinical Trials Group 175 Team.

Authorship 231716
type: Authorship
author rank in publication: 4
linked author: Hughes, Michael
linked information resource: HIV type 1 chemokine coreceptor use among antiretroviral-experienced patients screened for a clinical trial of a CCR5 inhibitor: AIDS Clinical Trial Group A5211.

Authorship 387666
type: Authorship
author rank in publication: 3
linked author: Hughes, Michael
linked information resource: A sequential design to estimate sensitivity and specificity of a diagnostic or screening test.

Authorship 389761
type: Authorship
author rank in publication: 7
linked author: Hughes, Michael
linked information resource: Risk factors for detectable HIV-1 RNA at delivery among women receiving highly active antiretroviral therapy in the women and infants transmission study.

Authorship 238756
type: Authorship
author rank in publication: 1
linked author: Hughes, Michael
linked information resource: Monitoring plasma HIV-1 RNA levels in addition to CD4+ lymphocyte count improves assessment of antiretroviral therapeutic response. ACTG 241 Protocol Virology Substudy Team.

Authorship 244190
type: Authorship
author rank in publication: 2
linked author: Hughes, Michael
linked information resource: Associations of chemokine receptor polymorphisms With HIV-1 mother-to-child transmission in sub-Saharan Africa: possible modulation of genetic effects by antiretrovirals.

Authorship 337993
type: Authorship
author rank in publication: 12
linked author: Hughes, Michael
linked information resource: Detection of replication-competent human immunodeficiency virus type 1 (HIV-1) in cultures from patients with levels of HIV-1 RNA in plasma suppressed to less than 500 or 50 copies per milliliter.

Authorship 416534
type: Authorship
author rank in publication: 10
linked author: Hughes, Michael
linked information resource: In utero nucleoside reverse transcriptase inhibitor exposure and signs of possible mitochondrial dysfunction in HIV-uninfected children.

Authorship 440142
type: Authorship
author rank in publication: 11
linked author: Hughes, Michael
linked information resource: Pharmacokinetics, safety and efficacy of lopinavir/ritonavir in infants less than 6 months of age: 24 week results.

Authorship 470931
type: Authorship
author rank in publication: 6
linked author: Hughes, Michael
linked information resource: Antiretroviral therapy during pregnancy and the risk of an adverse outcome.

Authorship 162348
type: Authorship
author rank in publication: 5
linked author: Hughes, Michael
linked information resource: Delayed onset of pubertal development in children and adolescents with perinatally acquired HIV infection.

Authorship 403859
type: Authorship
author rank in publication: 1
linked author: Hughes, Michael
linked information resource: The impact of stopping rules on heterogeneity of results in overviews of clinical trials.

Authorship 403921
type: Authorship
author rank in publication: 8
linked author: Hughes, Michael
linked information resource: Use of changes in plasma levels of human immunodeficiency virus type 1 RNA to assess the clinical benefit of antiretroviral therapy.

Authorship 362771
type: Authorship
author rank in publication: 5
linked author: Hughes, Michael
linked information resource: https://connects.catalyst.harvard.edu/Profiles/profile/1115920

Authorship 331379
type: Authorship
author rank in publication: 1
linked author: Hughes, Michael
linked information resource: Initial treatment of HIV infection: randomized trials with clinical end points are still needed.

Authorship 411345
type: Authorship
author rank in publication: 2
linked author: Hughes, Michael
linked information resource: https://connects.catalyst.harvard.edu/Profiles/profile/1099186

Authorship 802345
type: Authorship
author rank in publication: 4
linked author: Hughes, Michael
linked information resource: Factors associated with lack of viral suppression at delivery among highly active antiretroviral therapy-naive women with HIV: a cohort study.

Authorship 802032
type: Authorship
author rank in publication: 4
linked author: Hughes, Michael
linked information resource: Comparison of methods to account for implausible reporting of energy intake in epidemiologic studies.

Authorship 797774
type: Authorship
author rank in publication: 3
linked author: Hughes, Michael
linked information resource: An augmented SMS intervention to improve access to antenatal CD4 testing and ART initiation in HIV-infected pregnant women: a cluster randomized trial.

Authorship 803266
type: Authorship
author rank in publication: 7
linked author: Hughes, Michael
linked information resource: Non-invasive evaluation of therapeutic response in keloid scar using diffuse reflectance spectroscopy.

Authorship 803455
type: Authorship
author rank in publication: 3
linked author: Hughes, Michael
linked information resource: Dietary diabetes risk reduction score, race and ethnicity, and risk of type 2 diabetes in women.

Non-invasive evaluation of therapeutic response in keloid scar using diffuse reflectance spectroscopy.
PubMed Identifier: 25780731
author list: Hsu CK, Tzeng SY, Yang CC, Lee JY, Huang LL, Chen WR, Hughes M, Chen YW, Liao YK, Tseng SH
published in: Biomedical optics express
information resource reference: Non-invasive evaluation of therapeutic response in keloid scar using diffuse reflectance spectroscopy. Biomed Opt Express. 2015 Feb 01; 6(2):390-404.
journal title abbreviation: Biomed Opt Express
publication date: 2015-01-08T00:00:00
year: 2015
type: Academic Article
type: Article
type: Document
type: Information Resource

Dietary diabetes risk reduction score, race and ethnicity, and risk of type 2 diabetes in women.
PubMed Identifier: 25592193
author list: Rhee JJ, Mattei J, Hughes MD, Hu FB, Willett WC
published in: Diabetes care
information resource reference: Dietary diabetes risk reduction score, race and ethnicity, and risk of type 2 diabetes in women. Diabetes Care. 2015 Apr; 38(4):596-603.
journal title abbreviation: Diabetes Care
publication date: 2015-01-15T00:00:00
year: 2015
type: Academic Article
type: Article
type: Document
type: Information Resource

Comparison of methods to account for implausible reporting of energy intake in epidemiologic studies.
PubMed Identifier: 25656533
author list: Rhee JJ, Sampson L, Cho E, Hughes MD, Hu FB, Willett WC
published in: American journal of epidemiology
information resource reference: Comparison of methods to account for implausible reporting of energy intake in epidemiologic studies. Am J Epidemiol. 2015 Feb 15; 181(4):225-33.
journal title abbreviation: Am J Epidemiol
publication date: 2015-02-05T00:00:00
year: 2015
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 327232
type: Authorship
author rank in publication: 2
linked author: Hughes, Michael
linked information resource: Genetic polymorphisms in CX3CR1 predict HIV-1 disease progression in children independently of CD4+ lymphocyte count and HIV-1 RNA load.

Authorship 368455
type: Authorship
author rank in publication: 14
linked author: Hughes, Michael
linked information resource: Long-term observation of adolescents initiating HAART therapy: three-year follow-up.

Authorship 381524
type: Authorship
author rank in publication: 2
linked author: Hughes, Michael
linked information resource: Dose-finding designs for HIV studies.

Authorship 53503
type: Authorship
author rank in publication: 9
linked author: Hughes, Michael
linked information resource: A comparison of two dosing regimens of zidovudine in Thai adults with early symptomatic HIV infection. Conducting clinical HIV trials in South-East Asia.

Authorship 486487
type: Authorship
author rank in publication: 10
linked author: Hughes, Michael
linked information resource: Predictors of herpes simplex virus type 2 prevalence and incidence among bar and hotel workers in Moshi, Tanzania.

Authorship 496762
type: Authorship
author rank in publication: 4
linked author: Hughes, Michael
linked information resource: Quality of life for children and adolescents: impact of HIV infection and antiretroviral treatment.

Authorship 471844
type: Authorship
author rank in publication: 2
linked author: Hughes, Michael
linked information resource: Insulin-like growth factor-1 and lean body mass in HIV-infected children.

Authorship 818436
type: Authorship
author rank in publication: 15
linked author: Hughes, Michael
linked information resource: A Randomized Comparison of Anthropomorphic Changes With Preferred and Alternative Efavirenz-Based Antiretroviral Regimens in Diverse Multinational Settings.

Authorship 819157
type: Authorship
author rank in publication: 1
linked author: Hughes, Michael
linked information resource: Abnormalities of selenium but not of copper homeostasis may drive tissue fibrosis in patients with systemic sclerosis.

Abnormalities of selenium but not of copper homeostasis may drive tissue fibrosis in patients with systemic sclerosis.
PubMed Identifier: 25602061
author list: Hughes M, Cooper GJ, Wilkinson J, New P, Guy JM, Herrick AL
published in: Rheumatology (Oxford, England)
information resource reference: Abnormalities of selenium but not of copper homeostasis may drive tissue fibrosis in patients with systemic sclerosis. Rheumatology (Oxford). 2015 Apr; 54(4):747-8.
journal title abbreviation: Rheumatology (Oxford)
publication date: 2015-01-18T00:00:00
year: 2015
type: Academic Article
type: Article
type: Document
type: Information Resource

A Randomized Comparison of Anthropomorphic Changes With Preferred and Alternative Efavirenz-Based Antiretroviral Regimens in Diverse Multinational Settings.
PubMed Identifier: 26213694
author list: Erlandson KM, Taejaroenkul S, Smeaton L, Gupta A, Singini IL, Lama JR, Mngqibisa R, Firnhaber C, Cardoso SW, Kanyama C, Machado da Silva AL, Hakim JG, Kumarasamy N, Campbell TB, Hughes MD
published in: Open forum infectious diseases
information resource reference: A Randomized Comparison of Anthropomorphic Changes With Preferred and Alternative Efavirenz-Based Antiretroviral Regimens in Diverse Multinational Settings. Open Forum Infect Dis. 2015 Sep; 2(3):ofv095.
journal title abbreviation: Open Forum Infect Dis
publication date: 2015-06-24T00:00:00
year: 2015
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 473143
type: Authorship
author rank in publication: 3
linked author: Hughes, Michael
linked information resource: Risk factors for opportunistic illnesses in children with human immunodeficiency virus in the era of highly active antiretroviral therapy.

Authorship 575359
type: Authorship
author rank in publication: 2
linked author: Hughes, Michael
linked information resource: Autoregressive models for describing non-linear changes in biological parameters fitted using BUGS.

Authorship 61817
type: Authorship
author rank in publication: 3
linked author: Hughes, Michael
linked information resource: Prevalence of chemokine and chemokine receptor polymorphisms in seroprevalent children with symptomatic HIV-1 infection in the United States.

Authorship 366218
type: Authorship
author rank in publication: 6
linked author: Hughes, Michael
linked information resource: Sexual behavior, psychosocial and knowledge differences between consistent, inconsistent and non-users of condoms: a study of female bar and hotel workers in Moshi, Tanzania.

Authorship 389119
type: Authorship
author rank in publication: 3
linked author: Hughes, Michael
linked information resource: Genetic influence of CCR5, CCR2, and SDF1 variants on human immunodeficiency virus 1 (HIV-1)-related disease progression and neurological impairment, in children with symptomatic HIV-1 infection.

Authorship 848309
type: Authorship
author rank in publication: 2
linked author: Hughes, Michael
linked information resource: Severe Disability in a Patient With Rheumatoid Arthritis and Sickle Cell Anemia: An Underreported, But Yet a Potentially Treatable Combination of Diseases.

Severe Disability in a Patient With Rheumatoid Arthritis and Sickle Cell Anemia: An Underreported, But Yet a Potentially Treatable Combination of Diseases.
PubMed Identifier: 26587862
author list: Leung MH, Hughes M, Lane J, Basu S, Ryan K, Jones AK
published in: Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases
information resource reference: Severe Disability in a Patient With Rheumatoid Arthritis and Sickle Cell Anemia: An Underreported, But Yet a Potentially Treatable Combination of Diseases. J Clin Rheumatol. 2015 Dec; 21(8):458-9.
journal title abbreviation: J Clin Rheumatol
publication date: 2015-12-01T00:00:00
year: 2015
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 853353
type: Authorship
author rank in publication: 3
linked author: Hughes, Michael
linked information resource: In-utero triple antiretroviral exposure associated with decreased growth among HIV-exposed uninfected infants in Botswana.

In-utero triple antiretroviral exposure associated with decreased growth among HIV-exposed uninfected infants in Botswana.
PubMed Identifier: 26684818
author list: Powis KM, Smeaton L, Hughes MD, Tumbare EA, Souda S, Jao J, Wirth KE, Makhema J, Lockman S, Fawzi W, Essex M, Shapiro RL
published in: AIDS (London, England)
information resource reference: In-utero triple antiretroviral exposure associated with decreased growth among HIV-exposed uninfected infants in Botswana. AIDS. 2016 Jan; 30(2):211-20.
journal title abbreviation: AIDS
publication date: 2016-01-01T00:00:00
year: 2016
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 462409
type: Authorship
author rank in publication: 1
linked author: Hughes, Michael
linked information resource: Within-subject variation in CD4 lymphocyte count in asymptomatic human immunodeficiency virus infection: implications for patient monitoring.

Authorship 505718
type: Authorship
author rank in publication: 2
linked author: Hughes, Michael
linked information resource: https://connects.catalyst.harvard.edu/Profiles/profile/748679

Authorship 858145
type: Authorship
author rank in publication: 4
linked author: Hughes, Michael
linked information resource: Prioritizing HIV comparative effectiveness trials based on value of information: generic versus brand-name ART in the US.

Prioritizing HIV comparative effectiveness trials based on value of information: generic versus brand-name ART in the US.
PubMed Identifier: 26651525
author list: Pei PP, Weinstein MC, Li XC, Hughes MD, Paltiel AD, Hou T, Parker RA, Gaynes MR, Sax PE, Freedberg KA, Schackman BR, Walensky RP
published in: HIV clinical trials
information resource reference: Prioritizing HIV comparative effectiveness trials based on value of information: generic versus brand-name ART in the US. HIV Clin Trials. 2015 Nov; 16(6):207-18.
journal title abbreviation: HIV Clin Trials
publication date: 2015-12-11T00:00:00
year: 2015
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 861933
type: Authorship
author rank in publication: 1
linked author: Hughes, Michael
linked information resource: Prediction and impact of attacks of Raynaud's phenomenon, as judged by patient perception.

Prediction and impact of attacks of Raynaud's phenomenon, as judged by patient perception.
PubMed Identifier: 25752312
author list: Hughes M, Snapir A, Wilkinson J, Snapir D, Wigley FM, Herrick AL
published in: Rheumatology (Oxford, England)
information resource reference: Prediction and impact of attacks of Raynaud's phenomenon, as judged by patient perception. Rheumatology (Oxford). 2015 Aug; 54(8):1443-7.
journal title abbreviation: Rheumatology (Oxford)
publication date: 2015-03-09T00:00:00
year: 2015
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 308486
type: Authorship
author rank in publication: 4
linked author: Hughes, Michael
linked information resource: Phase 2 study of the safety and efficacy of vicriviroc, a CCR5 inhibitor, in HIV-1-Infected, treatment-experienced patients: AIDS clinical trials group 5211.

Authorship 417002
type: Authorship
author rank in publication: 2
linked author: Hughes, Michael
linked information resource: Meta-analysis for the evaluation of potential surrogate markers.

Authorship 879921
type: Authorship
author rank in publication: 2
linked author: Hughes, Michael
linked information resource: Evaluating predictors of competing risk outcomes when censoring depends on time-dependent covariates, with application to safety and efficacy of HIV treatment.

Authorship 880338
type: Authorship
author rank in publication: 1
linked author: Hughes, Michael
linked information resource: Method for modeling radiative transport in luminescent particulate media.

Method for modeling radiative transport in luminescent particulate media.
PubMed Identifier: 27140095
author list: Hughes MD, Borca-Tasciuc DA, Kaminski DA
published in: Applied optics
information resource reference: Method for modeling radiative transport in luminescent particulate media. Appl Opt. 2016 Apr 20; 55(12):3251-60.
journal title abbreviation: Appl Opt
publication date: 2016-04-20T00:00:00
year: 2016
type: Academic Article
type: Article
type: Document
type: Information Resource

Evaluating predictors of competing risk outcomes when censoring depends on time-dependent covariates, with application to safety and efficacy of HIV treatment.
PubMed Identifier: 26763556
author list: Lok JJ, Hughes MD
published in: Statistics in medicine
information resource reference: Evaluating predictors of competing risk outcomes when censoring depends on time-dependent covariates, with application to safety and efficacy of HIV treatment. Stat Med. 2016 06 15; 35(13):2183-94.
journal title abbreviation: Stat Med
publication date: 2016-01-14T00:00:00
year: 2016
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 479755
type: Authorship
author rank in publication: 3
linked author: Hughes, Michael
linked information resource: Can fluid resuscitation prevent pancreatic necrosis in severe acute pancreatitis?

Authorship 502877
type: Authorship
author rank in publication: 2
linked author: Hughes, Michael
linked information resource: Methodological approach used by Skowron et al.

Authorship 507358
type: Authorship
author rank in publication: 5
linked author: Hughes, Michael
linked information resource: Pharmacokinetic/pharmacodynamic modeling of the antiretroviral activity of the CCR5 antagonist Vicriviroc in treatment experienced HIV-infected subjects (ACTG protocol 5211).

Authorship 5590
type: Authorship
author rank in publication: 3
linked author: Hughes, Michael
linked information resource: The role of social networks and support in postpartum women's depression: a multiethnic urban sample.

Authorship 560094
type: Authorship
author rank in publication: 9
linked author: Hughes, Michael
linked information resource: Pharmacokinetics and safety of nelfinavir when used in combination with zidovudine and lamivudine in HIV-infected pregnant women: Pediatric AIDS Clinical Trials Group (PACTG) Protocol 353.

Authorship 575659
type: Authorship
author rank in publication: 4
linked author: Hughes, Michael
linked information resource: CCR5/delta(ccr5) heterozygosity: a selective pressure for the syncytium-inducing human immunodeficiency virus type 1 phenotype. NIAID AIDS Clinical Trials Group Protocol 241 Virology Team.

Authorship 888717
type: Authorship
author rank in publication: 11
linked author: Hughes, Michael
linked information resource: Nonnucleoside Reverse-transcriptase Inhibitor- vs Ritonavir-boosted Protease Inhibitor-based Regimens for Initial Treatment of HIV Infection: A Systematic Review and Metaanalysis of Randomized Trials.

Nonnucleoside Reverse-transcriptase Inhibitor- vs Ritonavir-boosted Protease Inhibitor-based Regimens for Initial Treatment of HIV Infection: A Systematic Review and Metaanalysis of Randomized Trials.
PubMed Identifier: 27090986
author list: Borges ÁH, Lundh A, Tendal B, Bartlett JA, Clumeck N, Costagliola D, Daar ES, Echeverría P, Gisslén M, Huedo-Medina TB, Hughes MD, Huppler Hullsiek K, Khabo P, Komati S, Kumar P, Lockman S, MacArthur RD, Maggiolo F, Matteelli A, Miro JM, Oka S, Petoumenos K, Puls RL, Riddler SA, Sax PE, Sierra-Madero J, Torti C, Lundgren JD
published in: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
information resource reference: Nonnucleoside Reverse-transcriptase Inhibitor- vs Ritonavir-boosted Protease Inhibitor-based Regimens for Initial Treatment of HIV Infection: A Systematic Review and Metaanalysis of Randomized Trials. Clin Infect Dis. 2016 07 15; 63(2):268-80.
journal title abbreviation: Clin Infect Dis
publication date: 2016-04-18T00:00:00
year: 2016
type: Academic Article
type: Article
type: Document
type: Information Resource

Associate Professor
sort order: 1
type: Faculty Rank

Full Professor
sort order: 0
type: Faculty Rank

Other Faculty
sort order: 5
type: Faculty Rank

Authorship 66305
type: Authorship
author rank in publication: 2
linked author: Hughes, Michael
linked information resource: Oxidant stress and peripheral neuropathy during antiretroviral therapy: an AIDS clinical trials group study.

Authorship 895310
type: Authorship
author rank in publication: 1
linked author: Hughes, Michael
linked information resource: Thermographic Abnormalities are Associated with Future Digital Ulcers and Death in Patients with Systemic Sclerosis.

Thermographic Abnormalities are Associated with Future Digital Ulcers and Death in Patients with Systemic Sclerosis.
PubMed Identifier: 27307532
author list: Hughes M, Wilkinson J, Moore T, Manning J, New P, Dinsdale G, Murray A, Herrick AL
published in: The Journal of rheumatology
information resource reference: Thermographic Abnormalities are Associated with Future Digital Ulcers and Death in Patients with Systemic Sclerosis. J Rheumatol. 2016 08; 43(8):1519-22.
journal title abbreviation: J Rheumatol
publication date: 2016-06-15T00:00:00
year: 2016
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 562222
type: Authorship
author rank in publication: 5
linked author: Hughes, Michael
linked information resource: In vivo emergence of vicriviroc resistance in a human immunodeficiency virus type 1 subtype C-infected subject.

Authorship 97335
type: Authorship
author rank in publication: 5
linked author: Hughes, Michael
linked information resource: Extensive diversity of Ig-superfamily proteins in the immune system of insects.

Statistical and Data Management Center for the AIDS Clinical Trials Group
end date: 2013-05-31
principal investigator name: HUGHES, MICHAEL DAVID
start date: 2006-06-29
type: Grant
sponsor award id: U01AI068634

Statistical/Data Management Center-Pediatric AIDS CTG
end date: 2007-02-28
principal investigator name: FENTON, TERRENCE
start date: 1997-03-01
type: Grant
sponsor award id: U01AI041110

Statistical and Data Management Center (SDMC), Advancing Clinical Therapeutics Globally for HIV/AIDS and Other Infections (ACTG)
end date: 2027-11-30
principal investigator name: HUGHES, MICHAEL DAVID
start date: 2006-06-29
type: Grant
sponsor award id: UM1AI068634

Statistical Methods in AIDS Research
end date: 2016-06-30
principal investigator name: HUGHES, MICHAEL DAVID
start date: 1987-04-01
type: Grant
sponsor award id: R01AI024643

STATISTICAL AND DATA MANAGEMENT CENTER
end date: 2006-12-31
principal investigator name: HUGHES, MICHAEL DAVID
start date: 1996-01-01
type: Grant
sponsor award id: U01AI038855

STATISTICAL METHODS IN AIDS RESEARCH
end date: 2011-06-30
principal investigator name: HUGHES, MICHAEL DAVID
start date: 1987-04-01
type: Grant
sponsor award id: R37AI024643

Co-Principal Investigator
type: Researcher Role
researcher role of: Hughes, Michael
contributes to: Statistical/Data Management Center-Pediatric AIDS CTG

Principal Investigator
type: Researcher Role
researcher role of: Hughes, Michael
contributes to: STATISTICAL METHODS IN AIDS RESEARCH

Principal Investigator
type: Researcher Role
researcher role of: Hughes, Michael
contributes to: Statistical and Data Management Center (SDMC), Advancing Clinical Therapeutics Globally for HIV/AIDS and Other Infections (ACTG)

Principal Investigator
type: Researcher Role
researcher role of: Hughes, Michael
contributes to: STATISTICAL AND DATA MANAGEMENT CENTER

Principal Investigator
type: Researcher Role
researcher role of: Hughes, Michael
contributes to: Statistical and Data Management Center for the AIDS Clinical Trials Group

Principal Investigator
type: Researcher Role
researcher role of: Hughes, Michael
contributes to: Statistical Methods in AIDS Research

Biostatistics/Epidemiology Training Grants in AIDS
end date: 2029-06-30
principal investigator name: HUGHES, MICHAEL DAVID
start date: 1989-09-01
type: Grant
sponsor award id: T32AI007358

Authorship 915986
type: Authorship
author rank in publication: 19
linked author: Hughes, Michael
linked information resource: A randomized, double-blind, placebo-controlled trial evaluating the safety of early oseltamivir treatment among children 0-9 years of age hospitalized with influenza in El Salvador and Panama.

A randomized, double-blind, placebo-controlled trial evaluating the safety of early oseltamivir treatment among children 0-9 years of age hospitalized with influenza in El Salvador and Panama.
PubMed Identifier: 27451343
author list: Dawood FS, Jara J, Gonzalez R, Castillo JM, De León T, Estripeaut D, Luciani K, Sujey Brizuela Y, Barahona A, Cazares RA, Lawson AM, Rodriguez M, de Viana D, Franco D, Castillo M, Fry AM, Gubareva L, Tamura D, Hughes M, Gargiullo P, Clara W, Azziz-Baumgartner E, Widdowson MA
published in: Antiviral research
information resource reference: A randomized, double-blind, placebo-controlled trial evaluating the safety of early oseltamivir treatment among children 0-9 years of age hospitalized with influenza in El Salvador and Panama. Antiviral Res. 2016 09; 133:85-94.
journal title abbreviation: Antiviral Res
publication date: 2016-07-21T00:00:00
year: 2016
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 83191
type: Authorship
author rank in publication: 5
linked author: Hughes, Michael
linked information resource: Neurodevelopment and in utero antiretroviral exposure of HIV-exposed uninfected infants.

Authorship 922353
type: Authorship
author rank in publication: 10
linked author: Hughes, Michael
linked information resource: Predictors of late virologic failure after initial successful suppression of HIV replication on efavirenz-based antiretroviral therapy.

Authorship 927280
type: Authorship
author rank in publication: 7
linked author: Hughes, Michael
linked information resource: Hyperlipidaemia in HIV-infected patients on lopinavir/ritonavir monotherapy in resource-limited settings.

Predictors of late virologic failure after initial successful suppression of HIV replication on efavirenz-based antiretroviral therapy.
PubMed Identifier: 27472067
author list: Singini I, Campbell TB, Smeaton LM, Kumarasamy N, La Rosa A, Taejareonkul S, Safren SA, Flanigan TP, Hakim JG, Hughes MD
published in: HIV clinical trials
information resource reference: Predictors of late virologic failure after initial successful suppression of HIV replication on efavirenz-based antiretroviral therapy. HIV Clin Trials. 2016; 17(5):173-180.
journal title abbreviation: HIV Clin Trials
publication date: 2016-07-29T00:00:00
year: 2016
type: Academic Article
type: Article
type: Document
type: Information Resource

Hyperlipidaemia in HIV-infected patients on lopinavir/ritonavir monotherapy in resource-limited settings.
PubMed Identifier: 27740537
author list: Matoga MM, Hosseinipour MC, Aga E, Ribaudo HJ, Kumarasamy N, Bartlett J, Hughes MD
published in: Antiviral therapy
information resource reference: Hyperlipidaemia in HIV-infected patients on lopinavir/ritonavir monotherapy in resource-limited settings. Antivir Ther. 2017; 22(3):205-213.
journal title abbreviation: Antivir Ther
publication date: 2016-10-14T00:00:00
year: 2016
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 933929
type: Authorship
author rank in publication: 3
linked author: Hughes, Michael
linked information resource: Stratified Weibull Regression Model for Interval-Censored Data.

Stratified Weibull Regression Model for Interval-Censored Data.
PubMed Identifier: 26835159
author list: Gu X, Shapiro D, Hughes MD, Balasubramanian R
published in: The R journal
information resource reference: Stratified Weibull Regression Model for Interval-Censored Data. R J. 2014 Jun; 6(1):31-40.
journal title abbreviation: R J
publication date: 2014-06-01T00:00:00
year: 2014
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 97178
type: Authorship
author rank in publication: 1
linked author: Hughes, Michael
linked information resource: Stopping guidelines for clinical trials with multiple treatments.

Authorship 201090
type: Authorship
author rank in publication: 4
linked author: Hughes, Michael
linked information resource: Drug development strategies for salvage therapy: conflicts and solutions.

Authorship 207336
type: Authorship
author rank in publication: 3
linked author: Hughes, Michael
linked information resource: Randomized controlled trial of feeding a concentrated formula to infants born to women infected by human immunodeficiency virus.

Authorship 334677
type: Authorship
author rank in publication: 2
linked author: Hughes, Michael
linked information resource: Lack of protective effects of interleukin-4 -589-C/T polymorphism against HIV-1-related disease progression and central nervous system impairment, in children.

Authorship 497997
type: Authorship
author rank in publication: 3
linked author: Hughes, Michael
linked information resource: Pharmacokinetics and safety of indinavir in human immunodeficiency virus-infected pregnant women.

Authorship 522018
type: Authorship
author rank in publication: 1
linked author: Hughes, Michael
linked information resource: Regression dilution in the proportional hazards model.

https://connects.catalyst.harvard.edu/Profiles/profile/745924
PubMed Identifier: 8813039
author list: Katzenstein DA, Hammer SM, Hughes MD, Gundacker H, Jackson JB, Fiscus S, Rasheed S, Elbeik T, Reichman R, Japour A, Merigan TC, Hirsch MS
published in: The New England journal of medicine
information resource reference: The relation of virologic and immunologic markers to clinical outcomes after nucleoside therapy in HIV-infected adults with 200 to 500 CD4 cells per cubic millimeter. AIDS Clinical Trials Group Study 175 Virology Study Team. N Engl J Med. 1996 Oct 10; 335(15):1091-8.
journal title abbreviation: N Engl J Med
publication date: 1996-10-10T00:00:00
year: 1996
type: Academic Article
type: Article
type: Document
type: Information Resource
label: The relation of virologic and immunologic markers to clinical outcomes after nucleoside therapy in HIV-infected adults with 200 to 500 CD4 cells per cubic millimeter. AIDS Clinical Trials Group Study 175 Virology Study Team.

A trial comparing nucleoside monotherapy with combination therapy in HIV-infected adults with CD4 cell counts from 200 to 500 per cubic millimeter. AIDS Clinical Trials Group Study 175 Study Team.
PubMed Identifier: 8813038
author list: Hammer SM, Katzenstein DA, Hughes MD, Gundacker H, Schooley RT, Haubrich RH, Henry WK, Lederman MM, Phair JP, Niu M, Hirsch MS, Merigan TC
published in: The New England journal of medicine
information resource reference: A trial comparing nucleoside monotherapy with combination therapy in HIV-infected adults with CD4 cell counts from 200 to 500 per cubic millimeter. AIDS Clinical Trials Group Study 175 Study Team. N Engl J Med. 1996 Oct 10; 335(15):1081-90.
journal title abbreviation: N Engl J Med
publication date: 1996-10-10T00:00:00
year: 1996
type: Academic Article
type: Article
type: Document
type: Information Resource

https://connects.catalyst.harvard.edu/Profiles/profile/748678
PubMed Identifier: 9498440
author list: Lathey JL, Hughes MD, Fiscus SA, Pi T, Jackson JB, Rasheed S, Elbeik T, Reichman R, Japour A, D'Aquila RT, Scott W, Griffith BP, Hammer SM, Katzenstein DA
published in: The Journal of infectious diseases
information resource reference: Variability and prognostic values of virologic and CD4 cell measures in human immunodeficiency virus type 1-infected patients with 200-500 CD4 cells/mm(3) (ACTG 175). AIDS Clinical Trials Group Protocol 175 Team. J Infect Dis. 1998 Mar; 177(3):617-24.
journal title abbreviation: J Infect Dis
publication date: 1998-03-01T00:00:00
year: 1998
type: Academic Article
type: Article
type: Document
type: Information Resource
label: Variability and prognostic values of virologic and CD4 cell measures in human immunodeficiency virus type 1-infected patients with 200-500 CD4 cells/mm(3) (ACTG 175). AIDS Clinical Trials Group Protocol 175 Team.

https://connects.catalyst.harvard.edu/Profiles/profile/748679
PubMed Identifier: 9498441
author list: Fiscus SA, Hughes MD, Lathey JL, Pi T, Jackson B, Rasheed S, Elbeik T, Reichman R, Japour A, Byington R, Scott W, Griffith BP, Katzenstein DA, Hammer SM
published in: The Journal of infectious diseases
information resource reference: Changes in virologic markers as predictors of CD4 cell decline and progression of disease in human immunodeficiency virus type 1-infected adults treated with nucleosides. AIDS Clinical Trials Group Protocol 175 Team. J Infect Dis. 1998 Mar; 177(3):625-33.
journal title abbreviation: J Infect Dis
publication date: 1998-03-01T00:00:00
year: 1998
type: Academic Article
type: Article
type: Document
type: Information Resource
label: Changes in virologic markers as predictors of CD4 cell decline and progression of disease in human immunodeficiency virus type 1-infected adults treated with nucleosides. AIDS Clinical Trials Group Protocol 175 Team.

Impact of protease inhibitor-containing combination antiretroviral therapies on height and weight growth in HIV-infected children.
PubMed Identifier: 11581480
author list: Buchacz K, Cervia JS, Lindsey JC, Hughes MD, Seage GR, Dankner WM, Oleske JM, Moye J
published in: Pediatrics
information resource reference: Impact of protease inhibitor-containing combination antiretroviral therapies on height and weight growth in HIV-infected children. Pediatrics. 2001 Oct; 108(4):E72.
journal title abbreviation: Pediatrics
publication date: 2001-10-01T00:00:00
year: 2001
type: Academic Article
type: Article
type: Document
type: Information Resource

Antiretroviral therapy during pregnancy and the risk of an adverse outcome.
PubMed Identifier: 12063370
author list: Tuomala RE, Shapiro DE, Mofenson LM, Bryson Y, Culnane M, Hughes MD, O'Sullivan MJ, Scott G, Stek AM, Wara D, Bulterys M
published in: The New England journal of medicine
information resource reference: Antiretroviral therapy during pregnancy and the risk of an adverse outcome. N Engl J Med. 2002 Jun 13; 346(24):1863-70.
journal title abbreviation: N Engl J Med
publication date: 2002-06-13T00:00:00
year: 2002
type: Academic Article
type: Article
type: Document
type: Information Resource

A comparison of bronchodilator therapy with or without inhaled corticosteroid therapy for obstructive airways disease. Dutch Chronic Non-Specific Lung Disease Study Group.
PubMed Identifier: 1357553
author list: Kerstjens HA, Brand PL, Hughes MD, Robinson NJ, Postma DS, Sluiter HJ, Bleecker ER, Dekhuijzen PN, de Jong PM, Mengelers HJ
published in: The New England journal of medicine
information resource reference: A comparison of bronchodilator therapy with or without inhaled corticosteroid therapy for obstructive airways disease. Dutch Chronic Non-Specific Lung Disease Study Group. N Engl J Med. 1992 Nov 12; 327(20):1413-9.
journal title abbreviation: N Engl J Med
publication date: 1992-11-12T00:00:00
year: 1992
type: Academic Article
type: Article
type: Document
type: Information Resource

Initial treatment of HIV infection: randomized trials with clinical end points are still needed.
PubMed Identifier: 16897649
author list: Hughes MD
published in: The Journal of infectious diseases
information resource reference: Initial treatment of HIV infection: randomized trials with clinical end points are still needed. J Infect Dis. 2006 Sep 01; 194(5):542-4.
journal title abbreviation: J Infect Dis
publication date: 2006-07-31T00:00:00
year: 2006
type: Academic Article
type: Article
type: Document
type: Information Resource

Subtle decreases in stavudine phenotypic susceptibility predict poor virologic response to stavudine monotherapy in zidovudine-experienced patients.
PubMed Identifier: 12394789
author list: Shulman NS, Hughes MD, Winters MA, Shafer RW, Zolopa AR, Hellmann NS, Bates M, Whitcomb JM, Katzenstein DA
published in: Journal of acquired immune deficiency syndromes (1999)
information resource reference: Subtle decreases in stavudine phenotypic susceptibility predict poor virologic response to stavudine monotherapy in zidovudine-experienced patients. J Acquir Immune Defic Syndr. 2002 Oct 01; 31(2):121-7.
journal title abbreviation: J Acquir Immune Defic Syndr
publication date: 2002-10-01T00:00:00
year: 2002
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 968690
type: Authorship
author rank in publication: 4
linked author: Hughes, Michael
linked information resource: Estimation of the cumulative incidence function under multiple dependent and independent censoring mechanisms.

Estimation of the cumulative incidence function under multiple dependent and independent censoring mechanisms.
PubMed Identifier: 28238045
author list: Lok JJ, Yang S, Sharkey B, Hughes MD
published in: Lifetime data analysis
information resource reference: Estimation of the cumulative incidence function under multiple dependent and independent censoring mechanisms. Lifetime Data Anal. 2018 04; 24(2):201-223.
journal title abbreviation: Lifetime Data Anal
publication date: 2017-02-25T00:00:00
year: 2017
type: Academic Article
type: Article
type: Document
type: Information Resource

https://connects.catalyst.harvard.edu/Profiles/profile/763589
PubMed Identifier: 10791875
author list: Kim S, Hughes MD, Hammer SM, Jackson JB, DeGruttola V, Katzenstein DA
published in: AIDS research and human retroviruses
information resource reference: Both serum HIV type 1 RNA levels and CD4+ lymphocyte counts predict clinical outcome in HIV type 1-infected subjects with 200 to 500 CD4+ cells per cubic millimeter. AIDS Clinical Trials Group Study 175 Virology Study Team. AIDS Res Hum Retroviruses. 2000 May 01; 16(7):645-53.
journal title abbreviation: AIDS Res Hum Retroviruses
publication date: 2000-05-01T00:00:00
year: 2000
type: Academic Article
type: Article
type: Document
type: Information Resource
label: Both serum HIV type 1 RNA levels and CD4+ lymphocyte counts predict clinical outcome in HIV type 1-infected subjects with 200 to 500 CD4+ cells per cubic millimeter. AIDS Clinical Trials Group Study 175 Virology Study Team.

Sexual behavior, psychosocial and knowledge differences between consistent, inconsistent and non-users of condoms: a study of female bar and hotel workers in Moshi, Tanzania.
PubMed Identifier: 16752083
author list: Tassiopoulos KK, Seage GR, Sam NE, Ao TT, Masenga EJ, Hughes MD, Kapiga SH
published in: AIDS and behavior
information resource reference: Sexual behavior, psychosocial and knowledge differences between consistent, inconsistent and non-users of condoms: a study of female bar and hotel workers in Moshi, Tanzania. AIDS Behav. 2006 Jul; 10(4):405-13.
journal title abbreviation: AIDS Behav
publication date: 2006-07-01T00:00:00
year: 2006
type: Academic Article
type: Article
type: Document
type: Information Resource

Estimation issues in clinical trials and overviews.
PubMed Identifier: 2145623
author list: Pocock SJ, Hughes MD
published in: Statistics in medicine
information resource reference: Estimation issues in clinical trials and overviews. Stat Med. 1990 Jun; 9(6):657-71.
journal title abbreviation: Stat Med
publication date: 1990-06-01T00:00:00
year: 1990
type: Academic Article
type: Article
type: Document
type: Information Resource

Prediction of short-term survival with an application in primary biliary cirrhosis.
PubMed Identifier: 1485056
author list: Hughes MD, Raskino CL, Pocock SJ, Biagini MR, Burroughs AK
published in: Statistics in medicine
information resource reference: Prediction of short-term survival with an application in primary biliary cirrhosis. Stat Med. 1992 Sep 30; 11(13):1731-45.
journal title abbreviation: Stat Med
publication date: 1992-09-30T00:00:00
year: 1992
type: Academic Article
type: Article
type: Document
type: Information Resource

Pharmacokinetics, safety and efficacy of lopinavir/ritonavir in infants less than 6 months of age: 24 week results.
PubMed Identifier: 18097227
author list: Chadwick EG, Capparelli EV, Yogev R, Pinto JA, Robbins B, Rodman JH, Chen J, Palumbo P, Serchuck L, Smith E, Hughes M
published in: AIDS (London, England)
information resource reference: Pharmacokinetics, safety and efficacy of lopinavir/ritonavir in infants less than 6 months of age: 24 week results. AIDS. 2008 Jan 11; 22(2):249-55.
journal title abbreviation: AIDS
publication date: 2008-01-11T00:00:00
year: 2008
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 972156
type: Authorship
author rank in publication: 3
linked author: Hughes, Michael
linked information resource: Sofosbuvir Plus Ribavirin Without Interferon for Treatment of Acute Hepatitis C Virus Infection in HIV-1-Infected Individuals: SWIFT-C.

Sofosbuvir Plus Ribavirin Without Interferon for Treatment of Acute Hepatitis C Virus Infection in HIV-1-Infected Individuals: SWIFT-C.
PubMed Identifier: 28329053
author list: Naggie S, Marks KM, Hughes M, Fierer DS, Macbrayne C, Kim A, Hollabaugh K, Roa J, Symonds B, Brainard DM, McHutchison JG, Peters MG, Kiser JJ, Chung R
published in: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
information resource reference: Sofosbuvir Plus Ribavirin Without Interferon for Treatment of Acute Hepatitis C Virus Infection in HIV-1-Infected Individuals: SWIFT-C. Clin Infect Dis. 2017 04 15; 64(8):1035-1042.
journal title abbreviation: Clin Infect Dis
publication date: 2017-04-15T00:00:00
year: 2017
type: Academic Article
type: Article
type: Document
type: Information Resource

The prevalence of pain in pediatric human immunodeficiency virus/acquired immunodeficiency syndrome as reported by participants in the Pediatric Late Outcomes Study (PACTG 219).
PubMed Identifier: 12042556
author list: Gaughan DM, Hughes MD, Seage GR, Selwyn PA, Carey VJ, Gortmaker SL, Oleske JM
published in: Pediatrics
information resource reference: The prevalence of pain in pediatric human immunodeficiency virus/acquired immunodeficiency syndrome as reported by participants in the Pediatric Late Outcomes Study (PACTG 219). Pediatrics. 2002 Jun; 109(6):1144-52.
journal title abbreviation: Pediatrics
publication date: 2002-06-01T00:00:00
year: 2002
type: Academic Article
type: Article
type: Document
type: Information Resource

Power considerations for clinical trials using multivariate time-to-event data.
PubMed Identifier: 9160485
author list: Hughes MD
published in: Statistics in medicine
information resource reference: Power considerations for clinical trials using multivariate time-to-event data. Stat Med. 1997 Apr 30; 16(8):865-82.
journal title abbreviation: Stat Med
publication date: 1997-04-30T00:00:00
year: 1997
type: Academic Article
type: Article
type: Document
type: Information Resource

Adjusting for regression toward the mean when variables are normally distributed.
PubMed Identifier: 9261912
author list: Lin HM, Hughes MD
published in: Statistical methods in medical research
information resource reference: Adjusting for regression toward the mean when variables are normally distributed. Stat Methods Med Res. 1997 Jun; 6(2):129-46.
journal title abbreviation: Stat Methods Med Res
publication date: 1997-06-01T00:00:00
year: 1997
type: Academic Article
type: Article
type: Document
type: Information Resource

Effect of lamivudine in HIV-infected persons with prior exposure to zidovudine/didanosine or zidovudine/zalcitabine.
PubMed Identifier: 11018853
author list: Albrecht MA, Hughes MD, Liou SH, Katzenstein DA, Murphy R, Balfour HH, Para MF, Valdez H, Hammer SM
published in: AIDS research and human retroviruses
information resource reference: Effect of lamivudine in HIV-infected persons with prior exposure to zidovudine/didanosine or zidovudine/zalcitabine. AIDS Res Hum Retroviruses. 2000 Sep 20; 16(14):1337-44.
journal title abbreviation: AIDS Res Hum Retroviruses
publication date: 2000-09-20T00:00:00
year: 2000
type: Academic Article
type: Article
type: Document
type: Information Resource

Prevalence of chemokine and chemokine receptor polymorphisms in seroprevalent children with symptomatic HIV-1 infection in the United States.
PubMed Identifier: 15076247
author list: Singh KK, Barroga CF, Hughes MD, Chen J, Raskino C, McKinney RE, Spector SA
published in: Journal of acquired immune deficiency syndromes (1999)
information resource reference: Prevalence of chemokine and chemokine receptor polymorphisms in seroprevalent children with symptomatic HIV-1 infection in the United States. J Acquir Immune Defic Syndr. 2004 Mar 01; 35(3):309-13.
journal title abbreviation: J Acquir Immune Defic Syndr
publication date: 2004-03-01T00:00:00
year: 2004
type: Academic Article
type: Article
type: Document
type: Information Resource

Risk factors for opportunistic illnesses in children with human immunodeficiency virus in the era of highly active antiretroviral therapy.
PubMed Identifier: 16894075
author list: Ylitalo N, Brogly S, Hughes MD, Nachman S, Dankner W, Van Dyke R, Seage GR
published in: Archives of pediatrics & adolescent medicine
information resource reference: Risk factors for opportunistic illnesses in children with human immunodeficiency virus in the era of highly active antiretroviral therapy. Arch Pediatr Adolesc Med. 2006 Aug; 160(8):778-87.
journal title abbreviation: Arch Pediatr Adolesc Med
publication date: 2006-08-01T00:00:00
year: 2006
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 977454
type: Authorship
author rank in publication: 2
linked author: Hughes, Michael
linked information resource: Effect of co-trimoxazole on mortality in HIV-exposed but uninfected children in Botswana (the Mpepu Study): a double-blind, randomised, placebo-controlled trial.

Effect of co-trimoxazole on mortality in HIV-exposed but uninfected children in Botswana (the Mpepu Study): a double-blind, randomised, placebo-controlled trial.
PubMed Identifier: 28395844
author list: Lockman S, Hughes M, Powis K, Ajibola G, Bennett K, Moyo S, van Widenfelt E, Leidner J, McIntosh K, Mazhani L, Makhema J, Essex M, Shapiro R
published in: The Lancet. Global health
information resource reference: Effect of co-trimoxazole on mortality in HIV-exposed but uninfected children in Botswana (the Mpepu Study): a double-blind, randomised, placebo-controlled trial. Lancet Glob Health. 2017 05; 5(5):e491-e500.
journal title abbreviation: Lancet Glob Health
publication date: 2017-05-01T00:00:00
year: 2017
type: Academic Article
type: Article
type: Document
type: Information Resource

Analysis of uncontrolled treatment changes in HIV clinical trails.
PubMed Identifier: 8896139
author list: Lin HM, Hughes MD
published in: Statistics in medicine
information resource reference: Analysis of uncontrolled treatment changes in HIV clinical trails. Stat Med. 1996 Oct 15; 15(19):2053-67.
journal title abbreviation: Stat Med
publication date: 1996-10-15T00:00:00
year: 1996
type: Academic Article
type: Article
type: Document
type: Information Resource

Meta-analysis for the evaluation of potential surrogate markers.
PubMed Identifier: 9304767
author list: Daniels MJ, Hughes MD
published in: Statistics in medicine
information resource reference: Meta-analysis for the evaluation of potential surrogate markers. Stat Med. 1997 Sep 15; 16(17):1965-82.
journal title abbreviation: Stat Med
publication date: 1997-09-15T00:00:00
year: 1997
type: Academic Article
type: Article
type: Document
type: Information Resource

Is severity of necrotizing pancreatitis increased in extended necrosis and infected necrosis?
PubMed Identifier: 12370532
author list: Perez A, Whang EE, Brooks DC, Moore FD, Hughes MD, Sica GT, Zinner MJ, Ashley SW, Banks PA
published in: Pancreas
information resource reference: Is severity of necrotizing pancreatitis increased in extended necrosis and infected necrosis? Pancreas. 2002 Oct; 25(3):229-33.
journal title abbreviation: Pancreas
publication date: 2002-10-01T00:00:00
year: 2002
type: Academic Article
type: Article
type: Document
type: Information Resource

Genetic influence of CCR5, CCR2, and SDF1 variants on human immunodeficiency virus 1 (HIV-1)-related disease progression and neurological impairment, in children with symptomatic HIV-1 infection.
PubMed Identifier: 14624371
author list: Singh KK, Barroga CF, Hughes MD, Chen J, Raskino C, McKinney RE, Spector SA
published in: The Journal of infectious diseases
information resource reference: Genetic influence of CCR5, CCR2, and SDF1 variants on human immunodeficiency virus 1 (HIV-1)-related disease progression and neurological impairment, in children with symptomatic HIV-1 infection. J Infect Dis. 2003 Nov 15; 188(10):1461-72.
journal title abbreviation: J Infect Dis
publication date: 2003-11-15T00:00:00
year: 2003
type: Academic Article
type: Article
type: Document
type: Information Resource

Virologic and CD4 cell response to zidovudine or zidovudine and lamivudine following didanosine treatment of human immunodeficiency virus infection.
PubMed Identifier: 11177402
author list: Katzenstein DA, Hughes MD, Albrecht M, Liou SH, Murphy R, Balfour H, Para M, Hammer S
published in: AIDS research and human retroviruses
information resource reference: Virologic and CD4 cell response to zidovudine or zidovudine and lamivudine following didanosine treatment of human immunodeficiency virus infection. AIDS Res Hum Retroviruses. 2001 Feb 10; 17(3):203-10.
journal title abbreviation: AIDS Res Hum Retroviruses
publication date: 2001-02-10T00:00:00
year: 2001
type: Academic Article
type: Article
type: Document
type: Information Resource

Predictors of virologic and clinical outcomes in HIV-1-infected patients receiving concurrent treatment with indinavir, zidovudine, and lamivudine. AIDS Clinical Trials Group Protocol 320.
PubMed Identifier: 11730396
author list: Demeter LM, Hughes MD, Coombs RW, Jackson JB, Grimes JM, Bosch RJ, Fiscus SA, Spector SA, Squires KE, Fischl MA, Hammer SM
published in: Annals of internal medicine
information resource reference: Predictors of virologic and clinical outcomes in HIV-1-infected patients receiving concurrent treatment with indinavir, zidovudine, and lamivudine. AIDS Clinical Trials Group Protocol 320. Ann Intern Med. 2001 Dec 04; 135(11):954-64.
journal title abbreviation: Ann Intern Med
publication date: 2001-12-04T00:00:00
year: 2001
type: Academic Article
type: Article
type: Document
type: Information Resource

CCR5/delta(ccr5) heterozygosity: a selective pressure for the syncytium-inducing human immunodeficiency virus type 1 phenotype. NIAID AIDS Clinical Trials Group Protocol 241 Virology Team.
PubMed Identifier: 9607832
author list: D'Aquila RT, Sutton L, Savara A, Hughes MD, Johnson VA
published in: The Journal of infectious diseases
information resource reference: CCR5/delta(ccr5) heterozygosity: a selective pressure for the syncytium-inducing human immunodeficiency virus type 1 phenotype. NIAID AIDS Clinical Trials Group Protocol 241 Virology Team. J Infect Dis. 1998 Jun; 177(6):1549-53.
journal title abbreviation: J Infect Dis
publication date: 1998-06-01T00:00:00
year: 1998
type: Academic Article
type: Article
type: Document
type: Information Resource

Statistical issues for HIV surrogate endpoints: point/counterpoint. An NIAID workshop.
PubMed Identifier: 9819838
author list: Albert JM, Ioannidis JP, Reichelderfer P, Conway B, Coombs RW, Crane L, Demasi R, Dixon DO, Flandre P, Hughes MD, Kalish LA, Larntz K, Lin D, Marschner IC, Muñoz A, Murray J, Neaton J, Pettinelli C, Rida W, Taylor JM, Welles SL
published in: Statistics in medicine
information resource reference: Statistical issues for HIV surrogate endpoints: point/counterpoint. An NIAID workshop. Stat Med. 1998 Nov 15; 17(21):2435-62.
journal title abbreviation: Stat Med
publication date: 1998-11-15T00:00:00
year: 1998
type: Academic Article
type: Article
type: Document
type: Information Resource

Increased risk of preterm delivery among HIV-infected women randomized to protease versus nucleoside reverse transcriptase inhibitor-based HAART during pregnancy.
PubMed Identifier: 21791651
author list: Powis KM, Kitch D, Ogwu A, Hughes MD, Lockman S, Leidner J, van Widenfelt E, Moffat C, Moyo S, Makhema J, Essex M, Shapiro RL
published in: The Journal of infectious diseases
information resource reference: Increased risk of preterm delivery among HIV-infected women randomized to protease versus nucleoside reverse transcriptase inhibitor-based HAART during pregnancy. J Infect Dis. 2011 Aug 15; 204(4):506-14.
journal title abbreviation: J Infect Dis
publication date: 2011-08-15T00:00:00
year: 2011
type: Academic Article
type: Article
type: Document
type: Information Resource

Safety and antiretroviral activity of chronic subcutaneous administration of T-20 in human immunodeficiency virus 1-infected children.
PubMed Identifier: 12237598
author list: Church JA, Cunningham C, Hughes M, Palumbo P, Mofenson LM, Delora P, Smith E, Wiznia A, Purdue L, Hawkins E, Sista P
published in: The Pediatric infectious disease journal
information resource reference: Safety and antiretroviral activity of chronic subcutaneous administration of T-20 in human immunodeficiency virus 1-infected children. Pediatr Infect Dis J. 2002 Jul; 21(7):653-9.
journal title abbreviation: Pediatr Infect Dis J
publication date: 2002-07-01T00:00:00
year: 2002
type: Academic Article
type: Article
type: Document
type: Information Resource

https://connects.catalyst.harvard.edu/Profiles/profile/799122
PubMed Identifier: 9287227
author list: Hammer SM, Squires KE, Hughes MD, Grimes JM, Demeter LM, Currier JS, Eron JJ, Feinberg JE, Balfour HH, Deyton LR, Chodakewitz JA, Fischl MA
published in: The New England journal of medicine
information resource reference: A controlled trial of two nucleoside analogues plus indinavir in persons with human immunodeficiency virus infection and CD4 cell counts of 200 per cubic millimeter or less. AIDS Clinical Trials Group 320 Study Team. N Engl J Med. 1997 Sep 11; 337(11):725-33.
journal title abbreviation: N Engl J Med
publication date: 1997-09-11T00:00:00
year: 1997
type: Academic Article
type: Article
type: Document
type: Information Resource
label: A controlled trial of two nucleoside analogues plus indinavir in persons with human immunodeficiency virus infection and CD4 cell counts of 200 per cubic millimeter or less. AIDS Clinical Trials Group 320 Study Team.

Meta-analysis of five randomized controlled trials comparing continuation of zidovudine versus switching to didanosine in HIV-infected individuals.
PubMed Identifier: 11327443
author list: Raboud JM, Montaner JS, Rae S, Kahn J, Hammer SM, Katzenstein DA, Pavia A, Dolin R, Hughes MD, Cross A, Beltangady M, Gatell J, Dunkle L, Smaldone L
published in: Antiviral therapy
information resource reference: Meta-analysis of five randomized controlled trials comparing continuation of zidovudine versus switching to didanosine in HIV-infected individuals. Antivir Ther. 1997 Dec; 2(4):237-47.
journal title abbreviation: Antivir Ther
publication date: 1997-12-01T00:00:00
year: 1997
type: Academic Article
type: Article
type: Document
type: Information Resource

Ritonavir-based highly active antiretroviral therapy in human immunodeficiency virus type 1-infected infants younger than 24 months of age.
PubMed Identifier: 16148846
author list: Chadwick EG, Rodman JH, Britto P, Powell C, Palumbo P, Luzuriaga K, Hughes M, Abrams EJ, Flynn PM, Borkowsky W, Yogev R
published in: The Pediatric infectious disease journal
information resource reference: Ritonavir-based highly active antiretroviral therapy in human immunodeficiency virus type 1-infected infants younger than 24 months of age. Pediatr Infect Dis J. 2005 Sep; 24(9):793-800.
journal title abbreviation: Pediatr Infect Dis J
publication date: 2005-09-01T00:00:00
year: 2005
type: Academic Article
type: Article
type: Document
type: Information Resource

https://connects.catalyst.harvard.edu/Profiles/profile/805857
PubMed Identifier: 1355640
author list: van Essen-Zandvliet EE, Hughes MD, Waalkens HJ, Duiverman EJ, Pocock SJ, Kerrebijn KF
published in: The American review of respiratory disease
information resource reference: Effects of 22 months of treatment with inhaled corticosteroids and/or beta-2-agonists on lung function, airway responsiveness, and symptoms in children with asthma. The Dutch Chronic Non-specific Lung Disease Study Group. Am Rev Respir Dis. 1992 Sep; 146(3):547-54.
journal title abbreviation: Am Rev Respir Dis
publication date: 1992-09-01T00:00:00
year: 1992
type: Academic Article
type: Article
type: Document
type: Information Resource
label: Effects of 22 months of treatment with inhaled corticosteroids and/or beta-2-agonists on lung function, airway responsiveness, and symptoms in children with asthma. The Dutch Chronic Non-specific Lung Disease Study Group.

Predictors and impact of patients lost to follow-up in a long-term randomized trial of immediate versus deferred antiretroviral treatment.
PubMed Identifier: 9377121
author list: Ioannidis JP, Bassett R, Hughes MD, Volberding PA, Sacks HS, Lau J
published in: Journal of acquired immune deficiency syndromes and human retrovirology : official publication of the International Retrovirology Association
information resource reference: Predictors and impact of patients lost to follow-up in a long-term randomized trial of immediate versus deferred antiretroviral treatment. J Acquir Immune Defic Syndr Hum Retrovirol. 1997 Sep 01; 16(1):22-30.
journal title abbreviation: J Acquir Immune Defic Syndr Hum Retrovirol
publication date: 1997-09-01T00:00:00
year: 1997
type: Academic Article
type: Article
type: Document
type: Information Resource

Use of changes in plasma levels of human immunodeficiency virus type 1 RNA to assess the clinical benefit of antiretroviral therapy.
PubMed Identifier: 9419168
author list: Marschner IC, Collier AC, Coombs RW, D'Aquila RT, DeGruttola V, Fischl MA, Hammer SM, Hughes MD, Johnson VA, Katzenstein DA, Richman DD, Smeaton LM, Spector SA, Saag MS
published in: The Journal of infectious diseases
information resource reference: Use of changes in plasma levels of human immunodeficiency virus type 1 RNA to assess the clinical benefit of antiretroviral therapy. J Infect Dis. 1998 Jan; 177(1):40-7.
journal title abbreviation: J Infect Dis
publication date: 1998-01-01T00:00:00
year: 1998
type: Academic Article
type: Article
type: Document
type: Information Resource

https://connects.catalyst.harvard.edu/Profiles/profile/806563
PubMed Identifier: 9869576
author list: Zhou XJ, Sheiner LB, D'Aquila RT, Hughes MD, Hirsch MS, Fischl MA, Johnson VA, Myers M, Sommadossi JP
published in: Antimicrobial agents and chemotherapy
information resource reference: Population pharmacokinetics of nevirapine, zidovudine, and didanosine in human immunodeficiency virus-infected patients. The National Institute of Allergy and Infectious Diseases AIDS Clinical Trials Group Protocol 241 Investigators. Antimicrob Agents Chemother. 1999 Jan; 43(1):121-8.
journal title abbreviation: Antimicrob Agents Chemother
publication date: 1999-01-01T00:00:00
year: 1999
type: Academic Article
type: Article
type: Document
type: Information Resource
label: Population pharmacokinetics of nevirapine, zidovudine, and didanosine in human immunodeficiency virus-infected patients. The National Institute of Allergy and Infectious Diseases AIDS Clinical Trials Group Protocol 241 Investigators.

Dose-finding designs for HIV studies.
PubMed Identifier: 11764240
author list: O'Quigley J, Hughes MD, Fenton T
published in: Biometrics
information resource reference: Dose-finding designs for HIV studies. Biometrics. 2001 Dec; 57(4):1018-29.
journal title abbreviation: Biometrics
publication date: 2001-12-01T00:00:00
year: 2001
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 983158
type: Authorship
author rank in publication: 20
linked author: Hughes, Michael
linked information resource: Immune plasma for the treatment of severe influenza: an open-label, multicentre, phase 2 randomised study.

Immune plasma for the treatment of severe influenza: an open-label, multicentre, phase 2 randomised study.
PubMed Identifier: 28522352
author list: Beigel JH, Tebas P, Elie-Turenne MC, Bajwa E, Bell TE, Cairns CB, Shoham S, Deville JG, Feucht E, Feinberg J, Luke T, Raviprakash K, Danko J, O'Neil D, Metcalf JA, King K, Burgess TH, Aga E, Lane HC, Hughes MD, Davey RT
published in: The Lancet. Respiratory medicine
information resource reference: Immune plasma for the treatment of severe influenza: an open-label, multicentre, phase 2 randomised study. Lancet Respir Med. 2017 06; 5(6):500-511.
journal title abbreviation: Lancet Respir Med
publication date: 2017-05-15T00:00:00
year: 2017
type: Academic Article
type: Article
type: Document
type: Information Resource

Efficacy, tolerability and pharmacokinetics of two nelfinavir-based regimens in human immunodeficiency virus-infected children and adolescents: pediatric AIDS clinical trials group protocol 403.
PubMed Identifier: 16220085
author list: King JR, Nachman S, Yogev R, Hodge J, Aldrovandi G, Hughes MD, Chen J, Wiznia A, Damle B, Acosta EP
published in: The Pediatric infectious disease journal
information resource reference: Efficacy, tolerability and pharmacokinetics of two nelfinavir-based regimens in human immunodeficiency virus-infected children and adolescents: pediatric AIDS clinical trials group protocol 403. Pediatr Infect Dis J. 2005 Oct; 24(10):880-5.
journal title abbreviation: Pediatr Infect Dis J
publication date: 2005-10-01T00:00:00
year: 2005
type: Academic Article
type: Article
type: Document
type: Information Resource

Psychiatric hospitalizations among children and youths with human immunodeficiency virus infection.
PubMed Identifier: 15173535
author list: Gaughan DM, Hughes MD, Oleske JM, Malee K, Gore CA, Nachman S
published in: Pediatrics
information resource reference: Psychiatric hospitalizations among children and youths with human immunodeficiency virus infection. Pediatrics. 2004 Jun; 113(6):e544-51.
journal title abbreviation: Pediatrics
publication date: 2004-06-01T00:00:00
year: 2004
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 985237
type: Authorship
author rank in publication: 10
linked author: Hughes, Michael
linked information resource: Antithrombotic therapy for atrial fibrillation: Antithrombotic Therapy and Prevention of Thrombosis, 9th ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines.

Predictors of herpes simplex virus type 2 prevalence and incidence among bar and hotel workers in Moshi, Tanzania.
PubMed Identifier: 17230408
author list: Tassiopoulos KK, Seage G, Sam N, Kiwelu I, Shao J, Ao TT, Essex M, Coplan P, Rosenberg Z, Hughes M, Kapiga S
published in: The Journal of infectious diseases
information resource reference: Predictors of herpes simplex virus type 2 prevalence and incidence among bar and hotel workers in Moshi, Tanzania. J Infect Dis. 2007 Feb 15; 195(4):493-501.
journal title abbreviation: J Infect Dis
publication date: 2007-01-04T00:00:00
year: 2007
type: Academic Article
type: Article
type: Document
type: Information Resource

Challenges in using observational studies to evaluate adverse effects of treatment.
PubMed Identifier: 17460224
author list: Hughes MD, Williams PL
published in: The New England journal of medicine
information resource reference: Challenges in using observational studies to evaluate adverse effects of treatment. N Engl J Med. 2007 Apr 26; 356(17):1705-7.
journal title abbreviation: N Engl J Med
publication date: 2007-04-26T00:00:00
year: 2007
type: Academic Article
type: Article
type: Document
type: Information Resource

Associations of chemokine receptor polymorphisms With HIV-1 mother-to-child transmission in sub-Saharan Africa: possible modulation of genetic effects by antiretrovirals.
PubMed Identifier: 18845960
author list: Singh KK, Hughes MD, Chen J, Phiri K, Rousseau C, Kuhn L, Coutsoudis A, Jackson JB, Guay LA, Musoke P, Mmiro F, Semba RD, Spector SA
published in: Journal of acquired immune deficiency syndromes (1999)
information resource reference: Associations of chemokine receptor polymorphisms With HIV-1 mother-to-child transmission in sub-Saharan Africa: possible modulation of genetic effects by antiretrovirals. J Acquir Immune Defic Syndr. 2008 Nov 01; 49(3):259-65.
journal title abbreviation: J Acquir Immune Defic Syndr
publication date: 2008-11-01T00:00:00
year: 2008
type: Academic Article
type: Article
type: Document
type: Information Resource

Pharmacokinetics and safety of indinavir in human immunodeficiency virus-infected pregnant women.
PubMed Identifier: 17158945
author list: Unadkat JD, Wara DW, Hughes MD, Mathias AA, Holland DT, Paul ME, Connor J, Huang S, Nguyen BY, Watts DH, Mofenson LM, Smith E, Deutsch P, Kaiser KA, Tuomala RE
published in: Antimicrobial agents and chemotherapy
information resource reference: Pharmacokinetics and safety of indinavir in human immunodeficiency virus-infected pregnant women. Antimicrob Agents Chemother. 2007 Feb; 51(2):783-6.
journal title abbreviation: Antimicrob Agents Chemother
publication date: 2006-12-11T00:00:00
year: 2006
type: Academic Article
type: Article
type: Document
type: Information Resource

The values of quantitative serum HIV-1 RNA levels and CD4 cell counts for predicting survival time among HIV-positive individuals with CD4 counts of < or = 50 x 10(6) cells/l.
PubMed Identifier: 10894278
author list: Coakley EP, Samore MH, Gillis JM, Hughes MD, Hammer SM
published in: AIDS (London, England)
information resource reference: The values of quantitative serum HIV-1 RNA levels and CD4 cell counts for predicting survival time among HIV-positive individuals with CD4 counts of < or = 50 x 10(6) cells/l. AIDS. 2000 Jun 16; 14(9):1147-53.
journal title abbreviation: AIDS
publication date: 2000-06-16T00:00:00
year: 2000
type: Academic Article
type: Article
type: Document
type: Information Resource

Methodological approach used by Skowron et al.
PubMed Identifier: 12048374
author list: Bosch R, Hughes M
published in: Journal of acquired immune deficiency syndromes (1999)
information resource reference: Methodological approach used by Skowron et al. J Acquir Immune Defic Syndr. 2002 May 01; 30(1):130-1.
journal title abbreviation: J Acquir Immune Defic Syndr
publication date: 2002-05-01T00:00:00
year: 2002
type: Academic Article
type: Article
type: Document
type: Information Resource

Antiretroviral regimens in pregnancy and breast-feeding in Botswana.
PubMed Identifier: 20554983
author list: Shapiro RL, Hughes MD, Ogwu A, Kitch D, Lockman S, Moffat C, Makhema J, Moyo S, Thior I, McIntosh K, van Widenfelt E, Leidner J, Powis K, Asmelash A, Tumbare E, Zwerski S, Sharma U, Handelsman E, Mburu K, Jayeoba O, Moko E, Souda S, Lubega E, Akhtar M, Wester C, Tuomola R, Snowden W, Martinez-Tristani M, Mazhani L, Essex M
published in: The New England journal of medicine
information resource reference: Antiretroviral regimens in pregnancy and breast-feeding in Botswana. N Engl J Med. 2010 Jun 17; 362(24):2282-94.
journal title abbreviation: N Engl J Med
publication date: 2010-06-17T00:00:00
year: 2010
type: Academic Article
type: Article
type: Document
type: Information Resource

Three-year safety and efficacy of vicriviroc, a CCR5 antagonist, in HIV-1-infected treatment-experienced patients.
PubMed Identifier: 20672447
author list: Wilkin TJ, Su Z, Krambrink A, Long J, Greaves W, Gross R, Hughes MD, Flexner C, Skolnik PR, Coakley E, Godfrey C, Hirsch M, Kuritzkes DR, Gulick RM
published in: Journal of acquired immune deficiency syndromes (1999)
information resource reference: Three-year safety and efficacy of vicriviroc, a CCR5 antagonist, in HIV-1-infected treatment-experienced patients. J Acquir Immune Defic Syndr. 2010 Aug; 54(5):470-6.
journal title abbreviation: J Acquir Immune Defic Syndr
publication date: 2010-08-01T00:00:00
year: 2010
type: Academic Article
type: Article
type: Document
type: Information Resource

Safety and pharmacokinetics of nelfinavir coadministered with zidovudine and lamivudine in infants during the first 6 weeks of life.
PubMed Identifier: 15905735
author list: Mirochnick M, Stek A, Acevedo M, Keller M, Holland D, Capparelli E, Connor J, Huang S, Hughes M, Watts H, Mofenson L, Bryson Y
published in: Journal of acquired immune deficiency syndromes (1999)
information resource reference: Safety and pharmacokinetics of nelfinavir coadministered with zidovudine and lamivudine in infants during the first 6 weeks of life. J Acquir Immune Defic Syndr. 2005 Jun 01; 39(2):189-94.
journal title abbreviation: J Acquir Immune Defic Syndr
publication date: 2005-06-01T00:00:00
year: 2005
type: Academic Article
type: Article
type: Document
type: Information Resource

A sequential design to estimate sensitivity and specificity of a diagnostic or screening test.
PubMed Identifier: 16374904
author list: Wruck LM, Yiannoutsos CT, Hughes MD
published in: Statistics in medicine
information resource reference: A sequential design to estimate sensitivity and specificity of a diagnostic or screening test. Stat Med. 2006 Oct 30; 25(20):3458-73.
journal title abbreviation: Stat Med
publication date: 2006-10-30T00:00:00
year: 2006
type: Academic Article
type: Article
type: Document
type: Information Resource

Clinical response and tolerability to and safety of saquinavir with low-dose ritonavir in human immunodeficiency virus type 1-infected mothers and their infants.
PubMed Identifier: 17420209
author list: Zorrilla CD, Van Dyke R, Bardeguez A, Acosta EP, Smith B, Hughes MD, Huang S, Watts DH, Heckman B, Jiménez E, McSherry G, Mofenson L
published in: Antimicrobial agents and chemotherapy
information resource reference: Clinical response and tolerability to and safety of saquinavir with low-dose ritonavir in human immunodeficiency virus type 1-infected mothers and their infants. Antimicrob Agents Chemother. 2007 Jun; 51(6):2208-10.
journal title abbreviation: Antimicrob Agents Chemother
publication date: 2007-04-09T00:00:00
year: 2007
type: Academic Article
type: Article
type: Document
type: Information Resource

Treatment responses in antiretroviral treatment-naive premenopausal and postmenopausal HIV-1-infected women: an analysis from AIDS Clinical Trials Group Studies.
PubMed Identifier: 19555288
author list: Patterson KB, Cohn SE, Uyanik J, Hughes M, Smurzynski M, Eron JJ
published in: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
information resource reference: Treatment responses in antiretroviral treatment-naive premenopausal and postmenopausal HIV-1-infected women: an analysis from AIDS Clinical Trials Group Studies. Clin Infect Dis. 2009 Aug 01; 49(3):473-6.
journal title abbreviation: Clin Infect Dis
publication date: 2009-08-01T00:00:00
year: 2009
type: Academic Article
type: Article
type: Document
type: Information Resource

Pharmacokinetic/pharmacodynamic modeling of the antiretroviral activity of the CCR5 antagonist Vicriviroc in treatment experienced HIV-infected subjects (ACTG protocol 5211).
PubMed Identifier: 20071999
author list: Crawford KW, Li C, Keung A, Su Z, Hughes MD, Greaves W, Kuritzkes D, Gulick R, Flexner C
published in: Journal of acquired immune deficiency syndromes (1999)
information resource reference: Pharmacokinetic/pharmacodynamic modeling of the antiretroviral activity of the CCR5 antagonist Vicriviroc in treatment experienced HIV-infected subjects (ACTG protocol 5211). J Acquir Immune Defic Syndr. 2010 Apr; 53(5):598-605.
journal title abbreviation: J Acquir Immune Defic Syndr
publication date: 2010-04-01T00:00:00
year: 2010
type: Academic Article
type: Article
type: Document
type: Information Resource

Dynamic calibration of pharmacokinetic parameters in dose-finding studies.
PubMed Identifier: 20203258
author list: O'Quigley J, Hughes MD, Fenton T, Pei L
published in: Biostatistics (Oxford, England)
information resource reference: Dynamic calibration of pharmacokinetic parameters in dose-finding studies. Biostatistics. 2010 Jul; 11(3):537-45.
journal title abbreviation: Biostatistics
publication date: 2010-03-04T00:00:00
year: 2010
type: Academic Article
type: Article
type: Document
type: Information Resource

Within-subject variation in CD4 lymphocyte count in asymptomatic human immunodeficiency virus infection: implications for patient monitoring.
PubMed Identifier: 7903975
author list: Hughes MD, Stein DS, Gundacker HM, Valentine FT, Phair JP, Volberding PA
published in: The Journal of infectious diseases
information resource reference: Within-subject variation in CD4 lymphocyte count in asymptomatic human immunodeficiency virus infection: implications for patient monitoring. J Infect Dis. 1994 Jan; 169(1):28-36.
journal title abbreviation: J Infect Dis
publication date: 1994-01-01T00:00:00
year: 1994
type: Academic Article
type: Article
type: Document
type: Information Resource

Antithrombotic therapy for atrial fibrillation: Antithrombotic Therapy and Prevention of Thrombosis, 9th ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines.
PubMed Identifier: 22315271
author list: You JJ, Singer DE, Howard PA, Lane DA, Eckman MH, Fang MC, Hylek EM, Schulman S, Go AS, Hughes M, Spencer FA, Manning WJ, Halperin JL, Lip GYH
published in: Chest
information resource reference: Antithrombotic therapy for atrial fibrillation: Antithrombotic Therapy and Prevention of Thrombosis, 9th ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines. Chest. 2012 Feb; 141(2 Suppl):e531S-e575S.
journal title abbreviation: Chest
publication date: 2012-02-01T00:00:00
year: 2012
type: Academic Article
type: Article
type: Document
type: Information Resource

Neuromuscular function in HIV infection: analysis of a placebo-controlled combination antiretroviral trial. AIDS Clinical Group 175/801 Study Team.
PubMed Identifier: 9875580
author list: Simpson DM, Katzenstein DA, Hughes MD, Hammer SM, Williamson DL, Jiang Q, Pi JT
published in: AIDS (London, England)
information resource reference: Neuromuscular function in HIV infection: analysis of a placebo-controlled combination antiretroviral trial. AIDS Clinical Group 175/801 Study Team. AIDS. 1998 Dec 24; 12(18):2425-32.
journal title abbreviation: AIDS
publication date: 1998-12-24T00:00:00
year: 1998
type: Academic Article
type: Article
type: Document
type: Information Resource

Analysis and design issues for studies using censored biomarker measurements with an example of viral load measurements in HIV clinical trials.
PubMed Identifier: 11113952
author list: Hughes MD
published in: Statistics in medicine
information resource reference: Analysis and design issues for studies using censored biomarker measurements with an example of viral load measurements in HIV clinical trials. Stat Med. 2000 Dec 15; 19(23):3171-91.
journal title abbreviation: Stat Med
publication date: 2000-12-15T00:00:00
year: 2000
type: Academic Article
type: Article
type: Document
type: Information Resource

In utero nucleoside reverse transcriptase inhibitor exposure and signs of possible mitochondrial dysfunction in HIV-uninfected children.
PubMed Identifier: 17457086
author list: Brogly SB, Ylitalo N, Mofenson LM, Oleske J, Van Dyke R, Crain MJ, Abzug MJ, Brady M, Jean-Philippe P, Hughes MD, Seage GR
published in: AIDS (London, England)
information resource reference: In utero nucleoside reverse transcriptase inhibitor exposure and signs of possible mitochondrial dysfunction in HIV-uninfected children. AIDS. 2007 May 11; 21(8):929-38.
journal title abbreviation: AIDS
publication date: 2007-05-11T00:00:00
year: 2007
type: Academic Article
type: Article
type: Document
type: Information Resource

Safety and efficacy of nevirapine- and efavirenz-based antiretroviral treatment in adults treated for TB-HIV co-infection in Botswana.
PubMed Identifier: 19275797
author list: Shipton LK, Wester CW, Stock S, Ndwapi N, Gaolathe T, Thior I, Avalos A, Moffat HJ, Mboya JJ, Widenfelt E, Essex M, Hughes MD, Shapiro RL
published in: The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease
information resource reference: Safety and efficacy of nevirapine- and efavirenz-based antiretroviral treatment in adults treated for TB-HIV co-infection in Botswana. Int J Tuberc Lung Dis. 2009 Mar; 13(3):360-6.
journal title abbreviation: Int J Tuberc Lung Dis
publication date: 2009-03-01T00:00:00
year: 2009
type: Academic Article
type: Article
type: Document
type: Information Resource

Vitamin D deficiency and anthropometric indicators of adiposity in school-age children: a prospective study.
PubMed Identifier: 20926524
author list: Gilbert-Diamond D, Baylin A, Mora-Plazas M, Marin C, Arsenault JE, Hughes MD, Willett WC, Villamor E
published in: The American journal of clinical nutrition
information resource reference: Vitamin D deficiency and anthropometric indicators of adiposity in school-age children: a prospective study. Am J Clin Nutr. 2010 Dec; 92(6):1446-51.
journal title abbreviation: Am J Clin Nutr
publication date: 2010-10-06T00:00:00
year: 2010
type: Academic Article
type: Article
type: Document
type: Information Resource

Quantitative deep sequencing reveals dynamic HIV-1 escape and large population shifts during CCR5 antagonist therapy in vivo.
PubMed Identifier: 19479085
author list: Tsibris AM, Korber B, Arnaout R, Russ C, Lo CC, Leitner T, Gaschen B, Theiler J, Paredes R, Su Z, Hughes MD, Gulick RM, Greaves W, Coakley E, Flexner C, Nusbaum C, Kuritzkes DR
published in: PloS one
information resource reference: Quantitative deep sequencing reveals dynamic HIV-1 escape and large population shifts during CCR5 antagonist therapy in vivo. PLoS One. 2009 May 25; 4(5):e5683.
journal title abbreviation: PLoS One
publication date: 2009-05-25T00:00:00
year: 2009
type: Academic Article
type: Article
type: Document
type: Information Resource

The impact of stopping rules on heterogeneity of results in overviews of clinical trials.
PubMed Identifier: 1581492
author list: Hughes MD, Freedman LS, Pocock SJ
published in: Biometrics
information resource reference: The impact of stopping rules on heterogeneity of results in overviews of clinical trials. Biometrics. 1992 Mar; 48(1):41-53.
journal title abbreviation: Biometrics
publication date: 1992-03-01T00:00:00
year: 1992
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1012250
type: Authorship
author rank in publication: 8
linked author: Hughes, Michael
linked information resource: Time to first positive HIV-1 DNA PCR may differ with antiretroviral regimen in infants infected with non-B subtype HIV-1.

Time to first positive HIV-1 DNA PCR may differ with antiretroviral regimen in infants infected with non-B subtype HIV-1.
PubMed Identifier: 28926397
author list: Balasubramanian R, Fowler MG, Dominguez K, Lockman S, Tookey PA, Huong NNG, Nesheim S, Hughes MD, Lallemant M, Tosswill J, Shaffer N, Sherman G, Palumbo P, Shapiro DE
published in: AIDS (London, England)
information resource reference: Time to first positive HIV-1 DNA PCR may differ with antiretroviral regimen in infants infected with non-B subtype HIV-1. AIDS. 2017 11 28; 31(18):2465-2474.
journal title abbreviation: AIDS
publication date: 2017-11-28T00:00:00
year: 2017
type: Academic Article
type: Article
type: Document
type: Information Resource

Lipid and glucose alterations in HIV-infected children beginning or changing antiretroviral therapy.
PubMed Identifier: 18519448
author list: Chantry CJ, Hughes MD, Alvero C, Cervia JS, Meyer WA, Hodge J, Borum P, Moye J
published in: Pediatrics
information resource reference: Lipid and glucose alterations in HIV-infected children beginning or changing antiretroviral therapy. Pediatrics. 2008 Jul; 122(1):e129-38.
journal title abbreviation: Pediatrics
publication date: 2008-06-02T00:00:00
year: 2008
type: Academic Article
type: Article
type: Document
type: Information Resource

Increased risk of severe infant anemia after exposure to maternal HAART, Botswana.
PubMed Identifier: 21266910
author list: Dryden-Peterson S, Shapiro RL, Hughes MD, Powis K, Ogwu A, Moffat C, Moyo S, Makhema J, Essex M, Lockman S
published in: Journal of acquired immune deficiency syndromes (1999)
information resource reference: Increased risk of severe infant anemia after exposure to maternal HAART, Botswana. J Acquir Immune Defic Syndr. 2011 Apr 15; 56(5):428-36.
journal title abbreviation: J Acquir Immune Defic Syndr
publication date: 2011-04-15T00:00:00
year: 2011
type: Academic Article
type: Article
type: Document
type: Information Resource

HIV-1 protease inhibitors and clinical malaria: a secondary analysis of the AIDS Clinical Trials Group A5208 study.
PubMed Identifier: 22123685
author list: Porter KA, Cole SR, Eron JJ, Zheng Y, Hughes MD, Lockman S, Poole C, Skinner-Adams TS, Hosseinipour M, Shaffer D, D'Amico R, Sawe FK, Siika A, Stringer E, Currier JS, Chipato T, Salata R, McCarthy JS, Meshnick SR
published in: Antimicrobial agents and chemotherapy
information resource reference: HIV-1 protease inhibitors and clinical malaria: a secondary analysis of the AIDS Clinical Trials Group A5208 study. Antimicrob Agents Chemother. 2012 Feb; 56(2):995-1000.
journal title abbreviation: Antimicrob Agents Chemother
publication date: 2011-11-28T00:00:00
year: 2011
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1014486
type: Authorship
author rank in publication: 18
linked author: Hughes, Michael
linked information resource: Oseltamivir, amantadine, and ribavirin combination antiviral therapy versus oseltamivir monotherapy for the treatment of influenza: a multicentre, double-blind, randomised phase 2 trial.

Oseltamivir, amantadine, and ribavirin combination antiviral therapy versus oseltamivir monotherapy for the treatment of influenza: a multicentre, double-blind, randomised phase 2 trial.
PubMed Identifier: 28958678
author list: Beigel JH, Bao Y, Beeler J, Manosuthi W, Slandzicki A, Dar SM, Panuto J, Beasley RL, Perez-Patrigeon S, Suwanpimolkul G, Losso MH, McClure N, Bozzolo DR, Myers C, Holley HP, Hoopes J, Lane HC, Hughes MD, Davey RT
published in: The Lancet. Infectious diseases
information resource reference: Oseltamivir, amantadine, and ribavirin combination antiviral therapy versus oseltamivir monotherapy for the treatment of influenza: a multicentre, double-blind, randomised phase 2 trial. Lancet Infect Dis. 2017 12; 17(12):1255-1265.
journal title abbreviation: Lancet Infect Dis
publication date: 2017-09-22T00:00:00
year: 2017
type: Academic Article
type: Article
type: Document
type: Information Resource

CD4 cell count as a surrogate endpoint in HIV clinical trials: a meta-analysis of studies of the AIDS Clinical Trials Group.
PubMed Identifier: 9792383
author list: Hughes MD, Daniels MJ, Fischl MA, Kim S, Schooley RT
published in: AIDS (London, England)
information resource reference: CD4 cell count as a surrogate endpoint in HIV clinical trials: a meta-analysis of studies of the AIDS Clinical Trials Group. AIDS. 1998 Oct 01; 12(14):1823-32.
journal title abbreviation: AIDS
publication date: 1998-10-01T00:00:00
year: 1998
type: Academic Article
type: Article
type: Document
type: Information Resource

CT-guided aspiration of suspected pancreatic infection: bacteriology and clinical outcome.
PubMed Identifier: 8708399
author list: Banks PA, Gerzof SG, Langevin RE, Silverman SG, Sica GT, Hughes MD
published in: International journal of pancreatology : official journal of the International Association of Pancreatology
information resource reference: CT-guided aspiration of suspected pancreatic infection: bacteriology and clinical outcome. Int J Pancreatol. 1995 Dec; 18(3):265-70.
journal title abbreviation: Int J Pancreatol
publication date: 1995-12-01T00:00:00
year: 1995
type: Academic Article
type: Article
type: Document
type: Information Resource

A comparison of two dosing regimens of zidovudine in Thai adults with early symptomatic HIV infection. Conducting clinical HIV trials in South-East Asia.
PubMed Identifier: 10800872
author list: Phanuphak P, Grayson ML, Sirivichayakul S, Suwanagool S, Ruxrungtham K, Hanvanich M, Ratanasuwan W, Ubolyam S, Hughes MD, Wanke CA, Hammer SM
published in: Australian and New Zealand journal of medicine
information resource reference: A comparison of two dosing regimens of zidovudine in Thai adults with early symptomatic HIV infection. Conducting clinical HIV trials in South-East Asia. Aust N Z J Med. 2000 Feb; 30(1):11-20.
journal title abbreviation: Aust N Z J Med
publication date: 2000-02-01T00:00:00
year: 2000
type: Academic Article
type: Article
type: Document
type: Information Resource

Virologic and immunologic outcomes after 24 weeks in HIV type 1-infected adolescents receiving highly active antiretroviral therapy.
PubMed Identifier: 15216461
author list: Flynn PM, Rudy BJ, Douglas SD, Lathey J, Spector SA, Martinez J, Silio M, Belzer M, Friedman L, D'Angelo L, McNamara J, Hodge J, Hughes MD, Lindsey JC
published in: The Journal of infectious diseases
information resource reference: Virologic and immunologic outcomes after 24 weeks in HIV type 1-infected adolescents receiving highly active antiretroviral therapy. J Infect Dis. 2004 Jul 15; 190(2):271-9.
journal title abbreviation: J Infect Dis
publication date: 2004-06-18T00:00:00
year: 2004
type: Academic Article
type: Article
type: Document
type: Information Resource

Impact of MCP-1-2518-G allele on the HIV-1 disease of children in the United States.
PubMed Identifier: 16439891
author list: Singh KK, Hughes MD, Chen J, Spector SA
published in: AIDS (London, England)
information resource reference: Impact of MCP-1-2518-G allele on the HIV-1 disease of children in the United States. AIDS. 2006 Feb 14; 20(3):475-8.
journal title abbreviation: AIDS
publication date: 2006-02-14T00:00:00
year: 2006
type: Academic Article
type: Article
type: Document
type: Information Resource

Drug development strategies for salvage therapy: conflicts and solutions.
PubMed Identifier: 17147496
author list: De Gruttola V, Flexner C, Schapiro J, Hughes M, Van Der Laan M, Kuritzkes DR
published in: AIDS research and human retroviruses
information resource reference: Drug development strategies for salvage therapy: conflicts and solutions. AIDS Res Hum Retroviruses. 2006 Nov; 22(11):1106-9.
journal title abbreviation: AIDS Res Hum Retroviruses
publication date: 2006-11-01T00:00:00
year: 2006
type: Academic Article
type: Article
type: Document
type: Information Resource

Phase 2 study of the safety and efficacy of vicriviroc, a CCR5 inhibitor, in HIV-1-Infected, treatment-experienced patients: AIDS clinical trials group 5211.
PubMed Identifier: 17570119
author list: Gulick RM, Su Z, Flexner C, Hughes MD, Skolnik PR, Wilkin TJ, Gross R, Krambrink A, Coakley E, Greaves WL, Zolopa A, Reichman R, Godfrey C, Hirsch M, Kuritzkes DR
published in: The Journal of infectious diseases
information resource reference: Phase 2 study of the safety and efficacy of vicriviroc, a CCR5 inhibitor, in HIV-1-Infected, treatment-experienced patients: AIDS clinical trials group 5211. J Infect Dis. 2007 Jul 15; 196(2):304-12.
journal title abbreviation: J Infect Dis
publication date: 2007-06-05T00:00:00
year: 2007
type: Academic Article
type: Article
type: Document
type: Information Resource

Assessing human immunodeficiency virus type 1 tropism: Comparison of assays using replication-competent virus versus plasma-derived pseudotyped virions.
PubMed Identifier: 19494074
author list: Hosoya N, Su Z, Wilkin T, Gulick RM, Flexner C, Hughes MD, Skolnik PR, Giguel F, Greaves WL, Coakley E, Kuritzkes DR
published in: Journal of clinical microbiology
information resource reference: Assessing human immunodeficiency virus type 1 tropism: Comparison of assays using replication-competent virus versus plasma-derived pseudotyped virions. J Clin Microbiol. 2009 Aug; 47(8):2604-6.
journal title abbreviation: J Clin Microbiol
publication date: 2009-06-03T00:00:00
year: 2009
type: Academic Article
type: Article
type: Document
type: Information Resource

Practical problems in interim analyses, with particular regard to estimation.
PubMed Identifier: 2605969
author list: Pocock SJ, Hughes MD
published in: Controlled clinical trials
information resource reference: Practical problems in interim analyses, with particular regard to estimation. Control Clin Trials. 1989 Dec; 10(4 Suppl):209S-221S.
journal title abbreviation: Control Clin Trials
publication date: 1989-12-01T00:00:00
year: 1989
type: Academic Article
type: Article
type: Document
type: Information Resource

Pharmacokinetics and safety of nelfinavir when used in combination with zidovudine and lamivudine in HIV-infected pregnant women: Pediatric AIDS Clinical Trials Group (PACTG) Protocol 353.
PubMed Identifier: 18474496
author list: Bryson YJ, Mirochnick M, Stek A, Mofenson LM, Connor J, Capparelli E, Watts DH, Huang S, Hughes MD, Kaiser K, Purdue L, Asfaw Y, Keller M, Smith E
published in: HIV clinical trials
information resource reference: Pharmacokinetics and safety of nelfinavir when used in combination with zidovudine and lamivudine in HIV-infected pregnant women: Pediatric AIDS Clinical Trials Group (PACTG) Protocol 353. HIV Clin Trials. 2008 Mar-Apr; 9(2):115-25.
journal title abbreviation: HIV Clin Trials
publication date: 2008-03-01T00:00:00
year: 2008
type: Academic Article
type: Article
type: Document
type: Information Resource

655 Huntington Ave
type: Address
address line 1: Harvard School of Public Health
address line 2: Bldg 2, Rm 439A
address line 3: 655 Huntington Ave
city: Boston
postal code: 02115
state or province: MA

Authorship 1025623
type: Authorship
author rank in publication: 7
linked author: Hughes, Michael
linked information resource: Cotrimoxazole prophylaxis was associated with enteric commensal bacterial resistance among HIV-exposed infants in a randomized controlled trial, Botswana.

Cotrimoxazole prophylaxis was associated with enteric commensal bacterial resistance among HIV-exposed infants in a randomized controlled trial, Botswana.
PubMed Identifier: 29119726
author list: Powis KM, Souda S, Lockman S, Ajibola G, Bennett K, Leidner J, Hughes MD, Moyo S, van Widenfelt E, Jibril HB, Makhema J, Essex M, Shapiro RL
published in: Journal of the International AIDS Society
information resource reference: Cotrimoxazole prophylaxis was associated with enteric commensal bacterial resistance among HIV-exposed infants in a randomized controlled trial, Botswana. J Int AIDS Soc. 2017 11; 20(3).
journal title abbreviation: J Int AIDS Soc
publication date: 2017-11-01T00:00:00
year: 2017
type: Academic Article
type: Article
type: Document
type: Information Resource

Quality of life for children and adolescents: impact of HIV infection and antiretroviral treatment.
PubMed Identifier: 16452344
author list: Lee GM, Gortmaker SL, McIntosh K, Hughes MD, Oleske JM
published in: Pediatrics
information resource reference: Quality of life for children and adolescents: impact of HIV infection and antiretroviral treatment. Pediatrics. 2006 Feb; 117(2):273-83.
journal title abbreviation: Pediatrics
publication date: 2006-02-01T00:00:00
year: 2006
type: Academic Article
type: Article
type: Document
type: Information Resource

Early archiving and predominance of nonnucleoside reverse transcriptase inhibitor-resistant HIV-1 among recently infected infants born in the United States.
PubMed Identifier: 17436219
author list: Persaud D, Palumbo P, Ziemniak C, Chen J, Ray SC, Hughes M, Havens P, Purswani M, Gaur AH, Chadwick EG
published in: The Journal of infectious diseases
information resource reference: Early archiving and predominance of nonnucleoside reverse transcriptase inhibitor-resistant HIV-1 among recently infected infants born in the United States. J Infect Dis. 2007 May 15; 195(10):1402-10.
journal title abbreviation: J Infect Dis
publication date: 2007-04-05T00:00:00
year: 2007
type: Academic Article
type: Article
type: Document
type: Information Resource

Reporting Bayesian analyses of clinical trials.
PubMed Identifier: 7902601
author list: Hughes MD
published in: Statistics in medicine
information resource reference: Reporting Bayesian analyses of clinical trials. Stat Med. 1993 Sep 30; 12(18):1651-63.
journal title abbreviation: Stat Med
publication date: 1993-09-30T00:00:00
year: 1993
type: Academic Article
type: Article
type: Document
type: Information Resource

Long-term increase in CD4+ T-cell counts during combination antiretroviral therapy for HIV-1 infection.
PubMed Identifier: 20467286
author list: Lok JJ, Bosch RJ, Benson CA, Collier AC, Robbins GK, Shafer RW, Hughes MD
published in: AIDS (London, England)
information resource reference: Long-term increase in CD4+ T-cell counts during combination antiretroviral therapy for HIV-1 infection. AIDS. 2010 Jul 31; 24(12):1867-76.
journal title abbreviation: AIDS
publication date: 2010-07-31T00:00:00
year: 2010
type: Academic Article
type: Article
type: Document
type: Information Resource

First-line antiretroviral therapy after single-dose nevirapine exposure in South Africa: a cost-effectiveness analysis of the OCTANE trial.
PubMed Identifier: 21293199
author list: Ciaranello AL, Lockman S, Freedberg KA, Hughes M, Chu J, Currier J, Wood R, Holmes CB, Pillay S, Conradie F, McIntyre J, Losina E, Walensky RP
published in: AIDS (London, England)
information resource reference: First-line antiretroviral therapy after single-dose nevirapine exposure in South Africa: a cost-effectiveness analysis of the OCTANE trial. AIDS. 2011 Feb 20; 25(4):479-92.
journal title abbreviation: AIDS
publication date: 2011-02-20T00:00:00
year: 2011
type: Academic Article
type: Article
type: Document
type: Information Resource

Genetic polymorphisms in CX3CR1 predict HIV-1 disease progression in children independently of CD4+ lymphocyte count and HIV-1 RNA load.
PubMed Identifier: 15871132
author list: Singh KK, Hughes MD, Chen J, Spector SA
published in: The Journal of infectious diseases
information resource reference: Genetic polymorphisms in CX3CR1 predict HIV-1 disease progression in children independently of CD4+ lymphocyte count and HIV-1 RNA load. J Infect Dis. 2005 Jun 01; 191(11):1971-80.
journal title abbreviation: J Infect Dis
publication date: 2005-04-28T00:00:00
year: 2005
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1029221
type: Authorship
author rank in publication: 8
linked author: Hughes, Michael
linked information resource: Defining Study Outcomes That Better Reflect Individual Response to Treatment.

Defining Study Outcomes That Better Reflect Individual Response to Treatment.
PubMed Identifier: 29189677
author list: Angelidou K, Palumbo P, Lindsey J, Violary A, Archary M, Barlow L, Claggett B, Hughes M, Wei LJ
published in: The Pediatric infectious disease journal
information resource reference: Defining Study Outcomes That Better Reflect Individual Response to Treatment. Pediatr Infect Dis J. 2018 03; 37(3):258-262.
journal title abbreviation: Pediatr Infect Dis J
publication date: 2018-03-01T00:00:00
year: 2018
type: Academic Article
type: Article
type: Document
type: Information Resource

A case-crossover analysis of predictors of condom use by female bar and hotel workers in Moshi, Tanzania.
PubMed Identifier: 19147705
author list: Tassiopoulos K, Kapiga S, Sam N, Ao TT, Hughes M, Seage GR
published in: International journal of epidemiology
information resource reference: A case-crossover analysis of predictors of condom use by female bar and hotel workers in Moshi, Tanzania. Int J Epidemiol. 2009 Apr; 38(2):552-60.
journal title abbreviation: Int J Epidemiol
publication date: 2009-01-15T00:00:00
year: 2009
type: Academic Article
type: Article
type: Document
type: Information Resource

Neurodevelopment and in utero antiretroviral exposure of HIV-exposed uninfected infants.
PubMed Identifier: 20083530
author list: Williams PL, Marino M, Malee K, Brogly S, Hughes MD, Mofenson LM
published in: Pediatrics
information resource reference: Neurodevelopment and in utero antiretroviral exposure of HIV-exposed uninfected infants. Pediatrics. 2010 Feb; 125(2):e250-60.
journal title abbreviation: Pediatrics
publication date: 2010-01-18T00:00:00
year: 2010
type: Academic Article
type: Article
type: Document
type: Information Resource

Practical issues arising in an exploratory analysis evaluating progression-free survival as a surrogate endpoint for overall survival in advanced colorectal cancer.
PubMed Identifier: 18285440
author list: Hughes MD
published in: Statistical methods in medical research
information resource reference: Practical issues arising in an exploratory analysis evaluating progression-free survival as a surrogate endpoint for overall survival in advanced colorectal cancer. Stat Methods Med Res. 2008 Oct; 17(5):487-95.
journal title abbreviation: Stat Methods Med Res
publication date: 2008-02-19T00:00:00
year: 2008
type: Academic Article
type: Article
type: Document
type: Information Resource

In vivo emergence of vicriviroc resistance in a human immunodeficiency virus type 1 subtype C-infected subject.
PubMed Identifier: 18495779
author list: Tsibris AM, Sagar M, Gulick RM, Su Z, Hughes M, Greaves W, Subramanian M, Flexner C, Giguel F, Leopold KE, Coakley E, Kuritzkes DR
published in: Journal of virology
information resource reference: In vivo emergence of vicriviroc resistance in a human immunodeficiency virus type 1 subtype C-infected subject. J Virol. 2008 Aug; 82(16):8210-4.
journal title abbreviation: J Virol
publication date: 2008-05-21T00:00:00
year: 2008
type: Academic Article
type: Article
type: Document
type: Information Resource

The design of single-arm clinical trials of combination antiretroviral regimens for treatment-naive HIV-infected patients.
PubMed Identifier: 23228206
author list: Zheng L, Rosenkranz SL, Taiwo B, Para MF, Eron JJ, Hughes MD
published in: AIDS research and human retroviruses
information resource reference: The design of single-arm clinical trials of combination antiretroviral regimens for treatment-naive HIV-infected patients. AIDS Res Hum Retroviruses. 2013 Apr; 29(4):652-7.
journal title abbreviation: AIDS Res Hum Retroviruses
publication date: 2013-01-09T00:00:00
year: 2013
type: Academic Article
type: Article
type: Document
type: Information Resource

Genotype assays and third-line ART in resource-limited settings: a simulation and cost-effectiveness analysis of a planned clinical trial.
PubMed Identifier: 22343964
author list: Lorenzana SB, Hughes MD, Grinsztejn B, Collier AC, Luz PM, Freedberg KA, Wood R, Levison JH, Mugyenyi PN, Salata R, Wallis CL, Weinstein MC, Schooley RT, Walensky RP
published in: AIDS (London, England)
information resource reference: Genotype assays and third-line ART in resource-limited settings: a simulation and cost-effectiveness analysis of a planned clinical trial. AIDS. 2012 Jun 01; 26(9):1083-93.
journal title abbreviation: AIDS
publication date: 2012-06-01T00:00:00
year: 2012
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1038394
type: Authorship
author rank in publication: 11
linked author: Hughes, Michael
linked information resource: Quality of life improvement in resource-limited settings after one year of second-line antiretroviral therapy use among adult men and women.

Authorship 1038261
type: Authorship
author rank in publication: 1
linked author: Hughes, Michael
linked information resource: Line-scanning fiber bundle endomicroscopy with a virtual detector slit.

Authorship 1038970
type: Authorship
author rank in publication: 12
linked author: Hughes, Michael
linked information resource: Quality of life among HIV-infected individuals failing first-line antiretroviral therapy in resource-limited settings.

Quality of life among HIV-infected individuals failing first-line antiretroviral therapy in resource-limited settings.
PubMed Identifier: 29343078
author list: Torres TS, Harrison LJ, La Rosa AM, Lavenberg JA, Zheng L, Safren SA, Ngongondo M, Poongulali S, Matoga M, Samaneka W, Collier AC, Hughes MD
published in: AIDS care
information resource reference: Quality of life among HIV-infected individuals failing first-line antiretroviral therapy in resource-limited settings. AIDS Care. 2018 08; 30(8):954-962.
journal title abbreviation: AIDS Care
publication date: 2018-01-18T00:00:00
year: 2018
type: Academic Article
type: Article
type: Document
type: Information Resource

Quality of life improvement in resource-limited settings after one year of second-line antiretroviral therapy use among adult men and women.
PubMed Identifier: 29334547
author list: Torres TS, Harrison LJ, La Rosa AM, Cardoso SW, Zheng L, Ngongondo M, Some F, Lalloo UG, Mwelase T, Collier AC, Hughes MD
published in: AIDS (London, England)
information resource reference: Quality of life improvement in resource-limited settings after one year of second-line antiretroviral therapy use among adult men and women. AIDS. 2018 03 13; 32(5):583-593.
journal title abbreviation: AIDS
publication date: 2018-03-13T00:00:00
year: 2018
type: Academic Article
type: Article
type: Document
type: Information Resource

Line-scanning fiber bundle endomicroscopy with a virtual detector slit.
PubMed Identifier: 27375942
author list: Hughes M, Yang GZ
published in: Biomedical optics express
information resource reference: Line-scanning fiber bundle endomicroscopy with a virtual detector slit. Biomed Opt Express. 2016 Jun 01; 7(6):2257-68.
journal title abbreviation: Biomed Opt Express
publication date: 2016-05-18T00:00:00
year: 2016
type: Academic Article
type: Article
type: Document
type: Information Resource

Long-term observation of adolescents initiating HAART therapy: three-year follow-up.
PubMed Identifier: 17961106
author list: Flynn PM, Rudy BJ, Lindsey JC, Douglas SD, Lathey J, Spector SA, Martinez J, Silio M, Belzer M, Friedman L, D'Angelo L, Smith E, Hodge J, Hughes MD
published in: AIDS research and human retroviruses
information resource reference: Long-term observation of adolescents initiating HAART therapy: three-year follow-up. AIDS Res Hum Retroviruses. 2007 Oct; 23(10):1208-14.
journal title abbreviation: AIDS Res Hum Retroviruses
publication date: 2007-10-01T00:00:00
year: 2007
type: Academic Article
type: Article
type: Document
type: Information Resource

A statistical framework for quantile equivalence clinical trials with application to pharmacokinetic studies that bridge from HIV-infected adults to children.
PubMed Identifier: 18261161
author list: Pei L, Hughes MD
published in: Biometrics
information resource reference: A statistical framework for quantile equivalence clinical trials with application to pharmacokinetic studies that bridge from HIV-infected adults to children. Biometrics. 2008 Dec; 64(4):1117-25.
journal title abbreviation: Biometrics
publication date: 2008-02-07T00:00:00
year: 2008
type: Academic Article
type: Article
type: Document
type: Information Resource

Highly active antiretroviral therapy versus zidovudine for prevention of mother-to-child transmission in a programmatic setting, Botswana.
PubMed Identifier: 21792062
author list: Dryden-Peterson S, Jayeoba O, Hughes MD, Jibril H, Keapoletswe K, Tlale J, Modise TA, Asmelash A, Moyo S, van Widenfelt E, Makhema J, Essex M, Shapiro RL, Lockman S
published in: Journal of acquired immune deficiency syndromes (1999)
information resource reference: Highly active antiretroviral therapy versus zidovudine for prevention of mother-to-child transmission in a programmatic setting, Botswana. J Acquir Immune Defic Syndr. 2011 Nov 01; 58(3):353-7.
journal title abbreviation: J Acquir Immune Defic Syndr
publication date: 2011-11-01T00:00:00
year: 2011
type: Academic Article
type: Article
type: Document
type: Information Resource

Nevirapine pharmacokinetics and risk of rash and hepatitis among HIV-infected sub-Saharan African women.
PubMed Identifier: 22301417
author list: Dong BJ, Zheng Y, Hughes MD, Frymoyer A, Verotta D, Lizak P, Sawe F, Currier JS, Lockman S, Aweeka FT
published in: AIDS (London, England)
information resource reference: Nevirapine pharmacokinetics and risk of rash and hepatitis among HIV-infected sub-Saharan African women. AIDS. 2012 Apr 24; 26(7):833-41.
journal title abbreviation: AIDS
publication date: 2012-04-24T00:00:00
year: 2012
type: Academic Article
type: Article
type: Document
type: Information Resource

High viral load and elevated angiogenic markers associated with increased risk of preeclampsia among women initiating highly active antiretroviral therapy in pregnancy in the Mma Bana study, Botswana.
PubMed Identifier: 23344545
author list: Powis KM, McElrath TF, Hughes MD, Ogwu A, Souda S, Datwyler SA, von Widenfelt E, Moyo S, Nádas M, Makhema J, Machakaire E, Lockman S, Essex M, Shapiro RL
published in: Journal of acquired immune deficiency syndromes (1999)
information resource reference: High viral load and elevated angiogenic markers associated with increased risk of preeclampsia among women initiating highly active antiretroviral therapy in pregnancy in the Mma Bana study, Botswana. J Acquir Immune Defic Syndr. 2013 Apr 15; 62(5):517-24.
journal title abbreviation: J Acquir Immune Defic Syndr
publication date: 2013-04-15T00:00:00
year: 2013
type: Academic Article
type: Article
type: Document
type: Information Resource

Monitoring plasma HIV-1 RNA levels in addition to CD4+ lymphocyte count improves assessment of antiretroviral therapeutic response. ACTG 241 Protocol Virology Substudy Team.
PubMed Identifier: 9182469
author list: Hughes MD, Johnson VA, Hirsch MS, Bremer JW, Elbeik T, Erice A, Kuritzkes DR, Scott WA, Spector SA, Basgoz N, Fischl MA, D'Aquila RT
published in: Annals of internal medicine
information resource reference: Monitoring plasma HIV-1 RNA levels in addition to CD4+ lymphocyte count improves assessment of antiretroviral therapeutic response. ACTG 241 Protocol Virology Substudy Team. Ann Intern Med. 1997 Jun 15; 126(12):929-38.
journal title abbreviation: Ann Intern Med
publication date: 1997-06-15T00:00:00
year: 1997
type: Academic Article
type: Article
type: Document
type: Information Resource

Intrahousehold allocation of energy intake among children under five years and their parents in rural Bangladesh.
PubMed Identifier: 9368809
author list: Kramer EM, Peterson KE, Rogers BL, Hughes MD
published in: European journal of clinical nutrition
information resource reference: Intrahousehold allocation of energy intake among children under five years and their parents in rural Bangladesh. Eur J Clin Nutr. 1997 Nov; 51(11):750-6.
journal title abbreviation: Eur J Clin Nutr
publication date: 1997-11-01T00:00:00
year: 1997
type: Academic Article
type: Article
type: Document
type: Information Resource

Authorship 1044392
type: Authorship
author rank in publication: 3
linked author: Hughes, Michael
linked information resource: https://connects.catalyst.harvard.edu/Profiles/profile/98128624

https://connects.catalyst.harvard.edu/Profiles/profile/98128624
PubMed Identifier: 29406428
author list: Ngongondo M, Miyahara S, Hughes MD, Sun X, Bisson GP, Gupta A, Kumwenda J, Lavenberg JA, Torres TS, Nyirenda M, Kidonge KK, Hosseinipour MC
published in: Journal of acquired immune deficiency syndromes (1999)
information resource reference: Hepatotoxicity During Isoniazid Preventive Therapy and Antiretroviral Therapy in People Living With HIV With Severe Immunosuppression: A Secondary Analysis of a Multi-Country Open-Label Randomized Controlled Clinical Trial. J Acquir Immune Defic Syndr. 2018 05 01; 78(1):54-61.
journal title abbreviation: J Acquir Immune Defic Syndr
publication date: 2018-05-01T00:00:00
year: 2018
type: Academic Article
type: Article
type: Document
type: Information Resource
label: Hepatotoxicity During Isoniazid Preventive Therapy and Antiretroviral Therapy in People Living With HIV With Severe Immunosuppression: A Secondary Analysis of a Multi-Country Open-Label Randomized Controlled Clinical Trial.

Autoregressive models for describing non-linear changes in biological parameters fitted using BUGS.
PubMed Identifier: 10521861
author list: Mander AP, Hughes MD, Sharp SJ, Lamm CJ
published in: Statistics in medicine
information resource reference: Autoregressive models for describing non-linear changes in biological parameters fitted using BUGS. Stat Med. 1999 Oct 30; 18(20):2709-22.
journal title abbreviation: Stat Med
publication date: 1999-10-30T00:00:00
year: 1999
type: Academic Article
type: Article
type: Document
type: Information Resource

Osteonecrosis of the hip (Legg-Calvé-Perthes disease) in human immunodeficiency virus-infected children.
PubMed Identifier: 11986480
author list: Gaughan DM, Mofenson LM, Hughes MD, Seage GR, Ciupak GL, Oleske JM
published in: Pediatrics
information resource reference: Osteonecrosis of the hip (Legg-Calvé-Perthes disease) in human immunodeficiency virus-infected children. Pediatrics. 2002 May; 109(5):E74-4.
journal title abbreviation: Pediatrics
publication date: 2002-05-01T00:00:00
year: 2002
type: Academic Article
type: Article
type: Document
type: Information Resource

Long-term effects of protease-inhibitor-based combination therapy on CD4 T-cell recovery in HIV-1-infected children and adolescents.
PubMed Identifier: 14697803
author list: Soh CH, Oleske JM, Brady MT, Spector SA, Borkowsky W, Burchett SK, Foca MD, Handelsman E, Jiménez E, Dankner WM, Hughes MD
published in: Lancet (London, England)
information resource reference: Long-term effects of protease-inhibitor-based combination therapy on CD4 T-cell recovery in HIV-1-infected children and adolescents. Lancet. 2003 Dec 20; 362(9401):2045-51.
journal title abbreviation: Lancet
publication date: 2003-12-20T00:00:00
year: 2003
type: Academic Article
type: Article
type: Document
type: Information Resource

Relationship of plasma HIV-1 RNA dynamics to baseline factors and virological responses to highly active antiretroviral therapy in adolescents (aged 12-22 years) infected through high-risk behavior.
PubMed Identifier: 14767811
author list: Wu H, Lathey J, Ruan P, Douglas SD, Spector SA, Lindsey J, Hughes MD, Rudy BJ, Flynn PM
published in: The Journal of infectious diseases
information resource reference: Relationship of plasma HIV-1 RNA dynamics to baseline factors and virological responses to highly active antiretroviral therapy in adolescents (aged 12-22 years) infected through high-risk behavior. J Infect Dis. 2004 Feb 15; 189(4):593-601.
journal title abbreviation: J Infect Dis
publication date: 2004-01-29T00:00:00
year: 2004
type: Academic Article
type: Article
type: Document
type: Information Resource