Receptor, Interferon alpha-beta
"Receptor, Interferon alpha-beta" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A ubiquitously expressed heterodimeric receptor that is specific for both INTERFERON-ALPHA and INTERFERON-BETA. It is composed of two subunits referred to as IFNAR1 and IFNAR2. The IFNAR2 subunit is believed to serve as the ligand-binding chain; however both chains are required for signal transduction. The interferon alpha-beta receptor signals through the action of JANUS KINASES such as the TYK2 KINASE.
MeSH Number(s)
D12.776.543.750.705.852.400.500
Concept/Terms
Receptor, Interferon alpha-beta- Receptor, Interferon alpha-beta
- Receptor, Interferon alpha beta
- IFN-alphaR
- Interferon alpha Receptor
- alpha Receptor, Interferon
- Type I Interferon Receptor
- Interferon alpha-beta Receptor
- Interferon alpha beta Receptor
- Interferon alphabeta Receptors
- Receptors, Interferon alphabeta
- Receptor, Interferon alpha
- IFN-alphabetaR
- IFN alphabetaR
- Interferon alpha Receptors
- Receptors, Interferon alpha
- alpha Receptors, Interferon
Interferon alpha-beta Receptor Chain 2- Interferon alpha-beta Receptor Chain 2
- Interferon alpha beta Receptor Chain 2
- Interferon alpha-beta Receptor IFNAR2 Subunit
- Interferon alpha beta Receptor IFNAR2 Subunit
- Interferon alpha-beta Receptor-2
- Interferon alpha beta Receptor 2
- Receptor-2, Interferon alpha-beta
- alpha-beta Receptor-2, Interferon
- IFNAR2 Subunit, Interferon alpha-beta Receptor
- IFNAR2 Subunit, Interferon alpha beta Receptor
Interferon alpha-beta Receptor Chain 1- Interferon alpha-beta Receptor Chain 1
- Interferon alpha beta Receptor Chain 1
- Interferon alpha-beta Receptor IFNAR1 Subunit
- Interferon alpha beta Receptor IFNAR1 Subunit
- Interferon alpha-beta Receptor-1
- Interferon alpha beta Receptor 1
- Receptor-1, Interferon alpha-beta
- alpha-beta Receptor-1, Interferon
- IFNAR1 Subunit, Interferon alpha-beta Receptor
- IFNAR1 Subunit, Interferon alpha beta Receptor
Below are MeSH descriptors whose meaning is more general than "Receptor, Interferon alpha-beta".
Below are MeSH descriptors whose meaning is more specific than "Receptor, Interferon alpha-beta".
This graph shows the total number of publications written about "Receptor, Interferon alpha-beta" by people in Harvard Catalyst Profiles by year, and whether "Receptor, Interferon alpha-beta" was a major or minor topic of these publication.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2001 | 0 | 1 | 1 |
| 2002 | 0 | 1 | 1 |
| 2003 | 0 | 1 | 1 |
| 2004 | 0 | 2 | 2 |
| 2005 | 0 | 1 | 1 |
| 2007 | 2 | 0 | 2 |
| 2008 | 1 | 1 | 2 |
| 2009 | 0 | 4 | 4 |
| 2010 | 0 | 6 | 6 |
| 2011 | 1 | 4 | 5 |
| 2013 | 1 | 2 | 3 |
| 2014 | 1 | 1 | 2 |
| 2015 | 0 | 3 | 3 |
| 2016 | 4 | 5 | 9 |
| 2017 | 1 | 6 | 7 |
| 2018 | 1 | 3 | 4 |
| 2019 | 2 | 4 | 6 |
| 2020 | 0 | 4 | 4 |
| 2021 | 1 | 4 | 5 |
Below are the most recent publications written about "Receptor, Interferon alpha-beta" by people in Profiles.
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The Astrocyte Type I Interferon Response Is Essential for Protection against Herpes Simplex Encephalitis. J Virol. 2022 02 23; 96(4):e0178321.
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Self-reactivity controls functional diversity of naive CD8+ T cells by co-opting tonic type I interferon. Nat Commun. 2021 10 18; 12(1):6059.
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Functional genomics atlas of synovial fibroblasts defining rheumatoid arthritis heritability. Genome Biol. 2021 08 25; 22(1):247.
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Endothelial STING controls T cell transmigration in an IFNI-dependent manner. JCI Insight. 2021 08 09; 6(15).
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Actionable druggable genome-wide Mendelian randomization identifies repurposing opportunities for COVID-19. Nat Med. 2021 04; 27(4):668-676.
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Integrin Alpha E (CD103) Limits Virus-Induced IFN-I Production in Conventional Dendritic Cells. Front Immunol. 2020; 11:607889.
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Genetic mechanisms of critical illness in COVID-19. Nature. 2021 03; 591(7848):92-98.
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AdrA as a Potential Immunomodulatory Candidate for STING-Mediated Antiviral Therapy That Required Both Type I IFN and TNF-a Production. J Immunol. 2021 01 15; 206(2):376-385.
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Type I interferon remodels lysosome function and modifies intestinal epithelial defense. Proc Natl Acad Sci U S A. 2020 11 24; 117(47):29862-29871.
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The myeloid type I interferon response to myocardial infarction begins in bone marrow and is regulated by Nrf2-activated macrophages. Sci Immunol. 2020 09 25; 5(51).