Mutagenesis, Site-Directed
"Mutagenesis, Site-Directed" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Genetically engineered MUTAGENESIS at a specific site in the DNA molecule that introduces a base substitution, or an insertion or deletion.
Concept/Terms
Mutagenesis, Site-Directed- Mutagenesis, Site-Directed
- Mutagenesis, Site Directed
- Site-Directed Mutagenesis
- Mutageneses, Site-Directed
- Site Directed Mutagenesis
- Site-Directed Mutageneses
- Site-Specific Mutagenesis
- Site Specific Mutagenesis
- Mutagenesis, Site-Specific
- Mutageneses, Site-Specific
- Mutagenesis, Site Specific
- Site-Specific Mutageneses
Oligonucleotide-Directed Mutagenesis- Oligonucleotide-Directed Mutagenesis
- Oligonucleotide Directed Mutagenesis
- Mutagenesis, Oligonucleotide-Directed
- Mutageneses, Oligonucleotide-Directed
- Mutagenesis, Oligonucleotide Directed
- Oligonucleotide-Directed Mutageneses
Below are MeSH descriptors whose meaning is more general than "Mutagenesis, Site-Directed".
Below are MeSH descriptors whose meaning is more specific than "Mutagenesis, Site-Directed".
This graph shows the total number of publications written about "Mutagenesis, Site-Directed" by people in Harvard Catalyst Profiles by year, and whether "Mutagenesis, Site-Directed" was a major or minor topic of these publication.
To see the data from this visualization as text,
click here.
Year | Major Topic | Minor Topic | Total |
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1994 | 3 | 57 | 60 |
1995 | 4 | 68 | 72 |
1996 | 0 | 83 | 83 |
1997 | 4 | 62 | 66 |
1998 | 5 | 59 | 64 |
1999 | 5 | 66 | 71 |
2000 | 4 | 72 | 76 |
2001 | 4 | 66 | 70 |
2002 | 2 | 73 | 75 |
2003 | 4 | 67 | 71 |
2004 | 1 | 41 | 42 |
2005 | 4 | 53 | 57 |
2006 | 0 | 38 | 38 |
2007 | 3 | 46 | 49 |
2008 | 0 | 30 | 30 |
2009 | 7 | 32 | 39 |
2010 | 1 | 32 | 33 |
2011 | 3 | 24 | 27 |
2012 | 0 | 27 | 27 |
2013 | 1 | 30 | 31 |
2014 | 1 | 22 | 23 |
2015 | 0 | 19 | 19 |
2016 | 1 | 18 | 19 |
2017 | 2 | 13 | 15 |
2018 | 1 | 14 | 15 |
2019 | 0 | 13 | 13 |
2020 | 1 | 14 | 15 |
2021 | 0 | 10 | 10 |
2022 | 1 | 0 | 1 |
Below are the most recent publications written about "Mutagenesis, Site-Directed" by people in Profiles.
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Targeted editing and evolution of engineered ribosomes in vivo by filtered editing. Nat Commun. 2022 01 10; 13(1):180.
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Functional assessment of somatic STK11 variants identified in primary human non-small cell lung cancers. Carcinogenesis. 2021 12 31; 42(12):1428-1438.
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Ig Enhancers Increase RNA Polymerase II Stalling at Somatic Hypermutation Target Sequences. J Immunol. 2022 01 01; 208(1):143-154.
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Biallelic inheritance in a single Pakistani family with intellectual disability implicates new candidate gene RDH14. Sci Rep. 2021 11 30; 11(1):23113.
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Roadmap for the use of base editors to decipher drug mechanism of action. PLoS One. 2021; 16(9):e0257537.
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Modifying TIMER to generate a slow-folding DsRed derivative for optimal use in quickly-dividing bacteria. PLoS Pathog. 2021 07; 17(7):e1009284.
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Mutagenesis and homology modeling reveal a predicted pocket of lysophosphatidylcholine acyltransferase 2 to catch Acyl-CoA. FASEB J. 2021 06; 35(6):e21501.
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Optimized CRISPR tools and site-directed transgenesis towards gene drive development in Culex quinquefasciatus mosquitoes. Nat Commun. 2021 May 20; 12(1):2960.
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In vivo CRISPR base editing of PCSK9 durably lowers cholesterol in primates. Nature. 2021 05; 593(7859):429-434.
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Hematoxylin binds to mutant calreticulin and disrupts its abnormal interaction with thrombopoietin receptor. Blood. 2021 04 08; 137(14):1920-1931.