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Adrenoleukodystrophy

"Adrenoleukodystrophy" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information
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An X-linked recessive disorder characterized by the accumulation of saturated very long chain fatty acids in the LYSOSOMES of ADRENAL CORTEX and the white matter of CENTRAL NERVOUS SYSTEM. This disease occurs almost exclusively in the males. Clinical features include the childhood onset of ATAXIA; NEUROBEHAVIORAL MANIFESTATIONS; HYPERPIGMENTATION; ADRENAL INSUFFICIENCY; SEIZURES; MUSCLE SPASTICITY; and DEMENTIA. The slowly progressive adult form is called adrenomyeloneuropathy. The defective gene ABCD1 is located at Xq28, and encodes the adrenoleukodystrophy protein (ATP-BINDING CASSETTE TRANSPORTERS).


publications
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This graph shows the total number of publications written about "Adrenoleukodystrophy" by people in Harvard Catalyst Profiles by year, and whether "Adrenoleukodystrophy" was a major or minor topic of these publication.
Bar chart showing 57 publications over 19 distinct years, with a maximum of 7 publications in 2021 and 2022
To see the data from this visualization as text, click here.
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