Lupus Erythematosus, Systemic
"Lupus Erythematosus, Systemic" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A chronic, relapsing, inflammatory, and often febrile multisystemic disorder of connective tissue, characterized principally by involvement of the skin, joints, kidneys, and serosal membranes. It is of unknown etiology, but is thought to represent a failure of the regulatory mechanisms of the autoimmune system. The disease is marked by a wide range of system dysfunctions, an elevated erythrocyte sedimentation rate, and the formation of LE cells in the blood or bone marrow.
Below are MeSH descriptors whose meaning is more general than "Lupus Erythematosus, Systemic".
Below are MeSH descriptors whose meaning is more specific than "Lupus Erythematosus, Systemic".
This graph shows the total number of publications written about "Lupus Erythematosus, Systemic" by people in Harvard Catalyst Profiles by year, and whether "Lupus Erythematosus, Systemic" was a major or minor topic of these publication.
To see the data from this visualization as text,
click here.
Year | Major Topic | Minor Topic | Total |
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1994 | 11 | 4 | 15 |
1995 | 17 | 2 | 19 |
1996 | 24 | 2 | 26 |
1997 | 26 | 5 | 31 |
1998 | 18 | 2 | 20 |
1999 | 20 | 1 | 21 |
2000 | 14 | 4 | 18 |
2001 | 15 | 3 | 18 |
2002 | 21 | 5 | 26 |
2003 | 16 | 6 | 22 |
2004 | 23 | 5 | 28 |
2005 | 22 | 9 | 31 |
2006 | 23 | 7 | 30 |
2007 | 27 | 2 | 29 |
2008 | 28 | 8 | 36 |
2009 | 29 | 6 | 35 |
2010 | 32 | 8 | 40 |
2011 | 40 | 5 | 45 |
2012 | 32 | 8 | 40 |
2013 | 33 | 12 | 45 |
2014 | 33 | 6 | 39 |
2015 | 31 | 6 | 37 |
2016 | 50 | 5 | 55 |
2017 | 43 | 8 | 51 |
2018 | 45 | 7 | 52 |
2019 | 56 | 9 | 65 |
2020 | 64 | 10 | 74 |
2021 | 68 | 9 | 77 |
2022 | 72 | 1 | 73 |
2023 | 45 | 0 | 45 |
2024 | 12 | 0 | 12 |
Below are the most recent publications written about "Lupus Erythematosus, Systemic" by people in Profiles.
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Invasion of spontaneous germinal centers by naive B cells is rapid and persistent. Sci Immunol. 2024 Mar 22; 9(93):eadi8150.
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Unmet need in rheumatology: reports from the Advances in Targeted Therapies meeting, 2023. Ann Rheum Dis. 2024 Mar 12; 83(4):409-416.
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Effect of remission, clinical remission with active serology, and glucocorticoid dosage on the pregnancy outcome of pregnant patients with systemic lupus erythematosus. Arthritis Res Ther. 2024 Mar 09; 26(1):63.
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A Disintegrin and metalloproteinase carves T cell abnormalities and pathogenesis in systemic lupus erythematosus. Clin Immunol. 2024 May; 262:110168.
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Qualitative interviews to support development of a patient-reported companion measure to the Glucocorticoid Toxicity Index. J Neurol Sci. 2024 Mar 15; 458:122907.
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CaMK4 controls follicular helper T cell expansion and function during normal and autoimmune T-dependent B cell responses. Nat Commun. 2024 Jan 29; 15(1):840.
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Mycophenolate mofetil withdrawal in patients with systemic lupus erythematosus: a multicentre, open-label, randomised controlled trial. Lancet Rheumatol. 2024 Mar; 6(3):e168-e177.
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Implications of Inflammatory Processes on a Developing Central Nervous System in Childhood-Onset Systemic Lupus Erythematosus. Arthritis Rheumatol. 2024 Mar; 76(3):332-344.
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Expert Perspective on a Clinical Challenge: Lupus and Pregnancy. Arthritis Rheumatol. 2024 Mar; 76(3):321-331.
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Lupus Nephritis Biomarkers: A Critical Review. Int J Mol Sci. 2024 Jan 09; 25(2).