Adaptor Proteins, Signal Transducing
"Adaptor Proteins, Signal Transducing" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A broad category of carrier proteins that play a role in SIGNAL TRANSDUCTION. They generally contain several modular domains, each of which having its own binding activity, and act by forming complexes with other intracellular-signaling molecules. Signal-transducing adaptor proteins lack enzyme activity, however their activity can be modulated by other signal-transducing enzymes
MeSH Number(s)
D12.644.360.024
D12.776.157.057
D12.776.476.024
Below are MeSH descriptors whose meaning is more general than "Adaptor Proteins, Signal Transducing".
Below are MeSH descriptors whose meaning is more specific than "Adaptor Proteins, Signal Transducing".
This graph shows the total number of publications written about "Adaptor Proteins, Signal Transducing" by people in Harvard Catalyst Profiles by year, and whether "Adaptor Proteins, Signal Transducing" was a major or minor topic of these publication.
To see the data from this visualization as text,
click here.
Year | Major Topic | Minor Topic | Total |
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1994 | 7 | 6 | 13 |
1995 | 20 | 2 | 22 |
1996 | 19 | 6 | 25 |
1997 | 17 | 8 | 25 |
1998 | 10 | 15 | 25 |
1999 | 13 | 23 | 36 |
2000 | 20 | 23 | 43 |
2001 | 19 | 32 | 51 |
2002 | 13 | 30 | 43 |
2003 | 11 | 29 | 40 |
2004 | 15 | 47 | 62 |
2005 | 12 | 39 | 51 |
2006 | 34 | 46 | 80 |
2007 | 24 | 38 | 62 |
2008 | 32 | 45 | 77 |
2009 | 29 | 40 | 69 |
2010 | 39 | 49 | 88 |
2011 | 38 | 35 | 73 |
2012 | 37 | 61 | 98 |
2013 | 41 | 46 | 87 |
2014 | 46 | 53 | 99 |
2015 | 53 | 61 | 114 |
2016 | 42 | 46 | 88 |
2017 | 44 | 48 | 92 |
2018 | 31 | 38 | 69 |
2019 | 47 | 32 | 79 |
2020 | 40 | 43 | 83 |
2021 | 39 | 29 | 68 |
2022 | 5 | 23 | 28 |
2023 | 7 | 20 | 27 |
2024 | 0 | 1 | 1 |
Below are the most recent publications written about "Adaptor Proteins, Signal Transducing" by people in Profiles.
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Induced protein degradation for therapeutics: past, present, and future. J Clin Invest. 2024 Jan 02; 134(1).
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All Roads Lead to Rome: YAP/TAZ Activity Influences Efficacy of KRASG12C Inhibitors. Cancer Res. 2023 12 15; 83(24):4005-4007.
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ChREBP is activated by reductive stress and mediates GCKR-associated metabolic traits. Cell Metab. 2024 Jan 02; 36(1):144-158.e7.
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CDK5R1, GSE1, HSPG2 and WDFY3 as indirect epigenetic-sensitive genes in atrial fibrillation. Eur J Clin Invest. 2024 Mar; 54(3):e14135.
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SQSTM1/p62 inhibition impairs pro-survival signaling in hypoxic human dendritic cells. Biochim Biophys Acta Mol Cell Res. 2024 02; 1871(2):119625.
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Multiscale genetic architecture of donor-recipient differences reveals intronic LIMS1 mismatches associated with kidney transplant survival. J Clin Invest. 2023 11 01; 133(21).
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Effects of HSP70 chaperones Ssa1 and Ssa2 on Ste5 scaffold and the mating mitogen-activated protein kinase (MAPK) pathway in Saccharomyces cerevisiae. PLoS One. 2023; 18(10):e0289339.
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Tissue-specific differences in the assembly of mitochondrial Complex I are revealed by a novel ENU mutation in ECSIT. Cardiovasc Res. 2023 10 16; 119(12):2213-2229.
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Genetic associations of TMEM154, PRC1 and ZFAND6 loci with type 2 diabetes in an endogamous business community of North India. PLoS One. 2023; 18(9):e0291339.
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DMD-Associated Dilated Cardiomyopathy: Genotypes, Phenotypes, and Phenocopies. Circ Genom Precis Med. 2023 10; 16(5):421-430.