"Genes, Homeobox" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Genes that encode highly conserved TRANSCRIPTION FACTORS that control positional identity of cells (BODY PATTERNING) and MORPHOGENESIS throughout development. Their sequences contain a 180 nucleotide sequence designated the homeobox, so called because mutations of these genes often results in homeotic transformations, in which one body structure replaces another. The proteins encoded by homeobox genes are called HOMEODOMAIN PROTEINS.
MeSH Number(s)
G05.360.340.024.340.230.500
Concept/Terms
Genes, Homeobox- Genes, Homeobox
- Gene, Homeobox
- Homeobox Gene
- Homeobox Genes
- Homeotic Genes
- Genes, Homeo Box
- Gene, Homeo Box
- Homeo Box Gene
- Homeo Box Genes
- Genes, Homeotic
- Gene, Homeotic
- Homeotic Gene
Homeo Box Sequence- Homeo Box Sequence
- Homeo Box Sequences
- Sequences, Homeo Box
- Homeo Boxes
- Homeobox
- Homeobox Sequence
- Homeobox Sequences
- Sequence, Homeobox
- Sequences, Homeobox
- Sequence, Homeo Box
- Homeo Box
- Homeoboxes
Below are MeSH descriptors whose meaning is more general than "Genes, Homeobox".
Below are MeSH descriptors whose meaning is more specific than "Genes, Homeobox".
This graph shows the total number of publications written about "Genes, Homeobox" by people in Harvard Catalyst Profiles by year, and whether "Genes, Homeobox" was a major or minor topic of these publication.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 7 | 5 | 12 |
| 1995 | 12 | 1 | 13 |
| 1996 | 6 | 8 | 14 |
| 1997 | 8 | 4 | 12 |
| 1998 | 5 | 5 | 10 |
| 1999 | 5 | 2 | 7 |
| 2000 | 5 | 3 | 8 |
| 2001 | 3 | 4 | 7 |
| 2002 | 3 | 3 | 6 |
| 2003 | 7 | 7 | 14 |
| 2004 | 6 | 3 | 9 |
| 2006 | 3 | 0 | 3 |
| 2007 | 1 | 3 | 4 |
| 2008 | 4 | 1 | 5 |
| 2009 | 3 | 1 | 4 |
| 2010 | 3 | 2 | 5 |
| 2011 | 3 | 2 | 5 |
| 2012 | 3 | 0 | 3 |
| 2013 | 3 | 2 | 5 |
| 2014 | 2 | 1 | 3 |
| 2015 | 0 | 2 | 2 |
| 2016 | 0 | 2 | 2 |
| 2017 | 3 | 1 | 4 |
| 2018 | 2 | 1 | 3 |
| 2019 | 1 | 2 | 3 |
| 2020 | 0 | 1 | 1 |
| 2021 | 0 | 2 | 2 |
| 2022 | 1 | 1 | 2 |
| 2023 | 0 | 2 | 2 |
| 2024 | 0 | 1 | 1 |
Below are the most recent publications written about "Genes, Homeobox" by people in Profiles.
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Animal and plant protein intake during infancy and childhood DNA methylation: a meta-analysis in the NutriPROGRAM consortium. Epigenetics. 2024 Dec; 19(1):2299045.
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Dominant frontonasal dysplasia with ectodermal defects results from increased activity of ALX4. Am J Med Genet A. 2023 12; 191(12):2806-2812.
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Spatial transcriptomics reveals a cnidarian segment polarity program in Nematostella vectensis. Curr Biol. 2023 07 10; 33(13):2678-2689.e5.
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Mitogen-activated protein kinase inhibition augments the T cell response against HOXB7-expressing tumor through human leukocyte antigen upregulation. Cancer Sci. 2023 Feb; 114(2):399-409.
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Generation of FLAG-tagged Arx knock-in mouse model. Genesis. 2022 07; 60(6-7):e23479.
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CHD4 is recruited by GATA4 and NKX2-5 to repress noncardiac gene programs in the developing heart. Genes Dev. 2022 04 01; 36(7-8):468-482.
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Comprehensive analysis of the homeobox family genes in breast cancer demonstrates their similar roles in cancer and development. Breast Cancer Res Treat. 2021 Apr; 186(2):353-361.
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Heritable pattern of oxidized DNA base repair coincides with pre-targeting of repair complexes to open chromatin. Nucleic Acids Res. 2021 01 11; 49(1):221-243.
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Requirement for LIM kinases in acute myeloid leukemia. Leukemia. 2020 12; 34(12):3173-3185.
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Hox genes maintain critical roles in the adult skeleton. Proc Natl Acad Sci U S A. 2020 03 31; 117(13):7296-7304.