Harvard Catalyst Profiles

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Caspase 1

"Caspase 1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information
Definition  |  Details  |  More General Concepts  |  Related Concepts  |  More Specific Concepts
A long pro-domain caspase that has specificity for the precursor form of INTERLEUKIN-1BETA. It plays a role in INFLAMMATION by catalytically converting the inactive forms of CYTOKINES such as interleukin-1beta to their active, secreted form. Caspase 1 is referred as interleukin-1beta converting enzyme and is frequently abbreviated ICE.


publications
Timeline   |   Most Recent
This graph shows the total number of publications written about "Caspase 1" by people in Harvard Catalyst Profiles by year, and whether "Caspase 1" was a major or minor topic of these publication.
Bar chart showing 142 publications over 29 distinct years, with a maximum of 11 publications in 2013 and 2022
To see the data from this visualization as text, click here.
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.